Bowie is a city in Prince George's County, Maryland. The population was 54,727 at the 2010 U.S. Census. Bowie has grown from a small railroad stop to the largest municipality in Prince George's County, and the fifth most populous city and third largest city by area in the U.S. state of Maryland. In 2014 CNN Money ranked Bowie 28th in its Best Places to Live in America list.