Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: it cannot fail; it ever speaks')Worship ("There is no worship now—the idol stands")of Lifeof the ("There is a winter in the godless heart")'s and the at ('I saw the city, 'twas not built by hands')The CrossNature ('Nature would speak through her first master man')and meat and drinkForgive me my trespassesin HeartThe ComplaintWhither shall I go from thy Spiritshall be LastThe LaborerThy Brother's of are passed away('They love me not, who at my table eat')The CityThe RoseFaith ('There is no faith; the mountain stands within')The JewSpring ('The stem that long has borne the wintry blast')and The EndNature ('The bubbling brook doth leap when I come by')! The Sign('I too will wait with thee returning spring')('Father! help them who walk in their own light')notice other days were pages givenThe CrocusThe PlantI am the WayThe kingdom of within you('There is no sound but thou dost hear my voice')The PreacherCome unto meFlee to the mountainsBlessed are they that mournFaith ('Hast thou but faith thou shalt the mountain bid')Redeeming the TimeTis FinishedEffortTo the pure all things are pureThe TaskSpring ('I have not lived the flesh has hedged me in')('The plant it springs it rears its drooping head')('Come thou and labor with me I will give')('The words I give thee they are not thine own')Joy ('The joy Thou giv'st no man can take away')HopeReliefJoy ('Thou hast a moon for every cloudy night')('I come the rushing wind that shook the place')of is every one who is born of the spiritThe SeedI am the Light of the the Bread of shall all the tribes of the earth mournRepent for the kingdom of Heaven is at handthe you is born a SaviourThe RedeemedHallowed be they NameTo him who overcomethof the Templeof as the World giveth('Open our eyes that we the world may see')Thy Father's HouseJacob's Wellof ('The voice that speaks when thou art in thy tomb')and ('Why are thou not awake my son? ')('not visit me?

Output: pass


Input: Claim: Personalized nutrition aims to tailor dietary advice based on genetic predispositions. [SEP] Text: Log in or new issue alertsGet alerts Enter your Email address: Subscribe to e2018. | DOI: 10. 4103/digm. digm_19_18 and Objectives: Diet plays a huge role in health, both by increasing metabolic disease risks and acutely through adverse interactions with diseases and medications. Multimorbid and polypharmaceutical patients are at a particularly high risk of such interactions due to the number of drugs they take. This leads to avoidable hospitalizations and poor compliance. This study built and demonstrated a tool that provides personalized dietary advice that accounts for a patient’s combination of disease and drugs in real-time on their mobile device. Methods: A comprehensive list of validated drug-disease-food interactions from several reputable sources was constructed. This was compiled into a knowledge graph using the RACE array logic platform. This interactions knowledge graph was used to power a personalized dietary advisor application on a mobile device. Results: Data from over 500,000 drug-disease-food interactions including 1,699 food ingredients and 9,526 disease interactions were compiled into a highly compressed knowledge model. This was used to inform recommendations for individual complex patients. It was also tested on virtual population of 10,000 multimorbid and polypharmaceutical patients. Conclusions: This study showed that digital health tools can provide highly contextual and adaptive responses from a single knowledge graph. The study showed it is possible to provide highly personalized health advice to complex patients in real-time on their own mobile device without having to hold such private information on a server. This enables highly secure, private and personalized digital health tools to be built. is difficult to overstate the importance of diet and lifestyle on health or the challenges that long-term poor choices and behaviors can create for public health and social care systems. As populations have become older and more affluent, they tend to adopt more sedentary lifestyles and less healthy diets. This has led to predictable increases in several chronic diseases, which now impose a huge burden on health and social care systems. [1] Preventable lifestyle-induced diseases with major dietary components, such as cardiovascular disease, Type 2 diabetes, cancer, and dementia now account for 65% of all health-care visits and 90% of deaths in the UK. [2] About 86% of all healthcare spending in the US covers people with chronic diseases, costing over $750B/year to treat.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Targeted phenolic characterization and antioxidant bioactivity of extracts from edible Acheta domesticus. Foods 10:102295 [86. 2022. Edible insects a novel food processing industry: an overview. Agric. Rev. 1:2357 [87. . 2022. Potential health benefits of edible insects. Crit. Rev. Food Sci. Nutr. 62:3499–508 [88. 2022. Dynamics in nutrients, sterols and total flavonoid content during processing of the edible long-horned grasshopper (Ruspolia differens Serville) for food. Food Chem. 383:132397 [89. . 2006. Phytosterols and vascular disease. Atherosclerosis 186:12–19 [90. . 2017. Endotoxin testing of a wound debridement device containing medicinal Lucilia sericata larvae. Regen 25:498–501 [91. 2014. Oxidative stress, prooxidants, and antioxidants: the interplay. BioMed. Res. Int. 2014:761264 [92. Rahnamaeian M, Cytryńska M, Zdybicka- 2015. Insect antimicrobial peptides show potentiating functional interactions against Gram-negative bacteria. Proc. R. Soc. B 282:20150293 [93. Ramos-Elorduy J. 2008. Energy supplied by edible insects from Mexico and their nutritional and ecological importance. Ecol. Food Nutr. 47:280–97 [94. . 2014. Recent advances in developing insect natural products as potential modern day medicines. Evid. Based Complement. . Altern. Med. 2:904958 [95. . 2011. Insect natural products and processes: new treatments for human disease. Insect Biochem. Mol. Biol. 41:747–69 [96. Raubenheimer D, Rothman JM. 2013. Nutritional ecology of entomophagy in humans and other primates. Annu. Rev. Entomol. 58:141–60 [97. -Pinto B, Fonseca J. 2018. Allergic risks of consuming edible insects: a systematic review. Mol. Nutr. Food Res. 62:1700030 [98. Sá. 2020. Food processing for the improvement of plant proteins digestibility. Crit. Rev. Food Sci.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: ')-ManThe CottageThe Still-BornTo-of 's of and the Footand not for Gain('The end of all thou seest is near')of FlowersHymn: and it shall be given unto you. from WithinThou know'st not what thy Lord will sayof the JustDeathThe Birth-Day of the SoulHiveTime's Houseand the BirdFaith and Light('where is it? hath it voice')('Stay where thou art, thou need'st not further go')'s Island Lightof Godof the BooksThe Robin's ('Tis all a great show')on Reading the Death of Rev. Henry Ware, Jr. BrightGod's at the ('There are towers; where they are')ye sow, so shall ye reap's RetortThe WidowImpatienceAbdolonymus—'s by FaithSalem ("Boast not, my native spot, thy sons were first")Spring in the SoulNature's InvitationChrist's CompassionHymn: Nevertheless, when the Son of Man cometh, shall he find faith on the earth? :8of 'to LiveThe Indian's the late in 's : Suggested by an EngravingThoughts and DesiresHymn ('As by the quickening breath of Spring')The Soul's : of the Rev. James Flint, D. D. , On reading his Collection of on the of J. Esq. July 22d, 1853the at the Thompson Jubilee, at Barre, Jany. 12, 1854: Sung at the Celebration of the Fourth of July, in Salem, 1854? To the Memory of the Rev. James Flint, D. D. and WorldlyHymn: So also will God, through Jesus, bring with him them who sleep'Blessed are they that mourn: for they shall be comforted' Math. 5:4To the Memory of the Rev. of -cleave not to the things of earth's the Rev. C. H. A. Dall, in IndiaHymn: Sung at the Dedication of Plummer Hall, Salem, Oct.

Output: pass


Input: Claim: Personalized nutrition aims to tailor dietary advice based on genetic predispositions. [SEP] Text: Standard public health messages such as the UK’s “eat 5 (portions of fruit and vegetables) a day” do not account for and may even conflict with the personal requirements of polypharmaceutical patients. Elderly and multimorbid adults are particularly vulnerable to ADRs due to the number of drugs they are prescribed[17] and over-the-counter and herbal medications and supplements they are taking. Identifying these potentially harmful drug-disease-food interactions is not as simple as looking up a list of all known interactions. Even ostensibly simple and well-known interactions - for example “green leafy vegetables reduce the efficacy of warfarin” - are complex. Warfarin interferes with the liver’s ability to process vitamin K (which occurs in high levels in leafy greens) and inhibits production of blood clotting proteins. High dietary levels of vitamin K overcome the inhibitory effect of warfarin, leading to more natural clotting and leaving some patients exposed to increased the risk of stroke. [18] Multiple other factors such as painkillers, antibiotics, dietary supplements, or alcohol also affect the clotting cascade and vitamin K levels. itself also goes on to affect other processes in the body and impacts on liver disease, cystic fibrosis, diarrhea, and digestive conditions,[19] which in turn affect how foods are absorbed. The network of connections is therefore intricately intertwined and difficult to deconvolute and test comprehensively. It is also well-known that generic lifestyle and dietary advice is not just ineffective at changing behavior but may be actively ignored or mistrusted by patients. [20] When provided, it is often insufficiently engaging, accessible and actionable and tends to have a generic wellness or single disease (e. g. , diabetes or obesity) focus, rather than considering the patient’s personal diseases, medicines, and risk factors. This fails to effectively communicate risks and personalize dietary advice in a form that people can remember, engage with and use in their daily lives. A tool that can provide real-time personalized advice accounting for a full range of the patient’s circumstances is therefore required. The precisionlife DIET system was developed to provide patients and carers with this personalized advice on demand as to whether particular foods or ingredients are going to present a risk of interactions for them and to suggest alternative products that will not cause such an issue for them.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Nutr. 60:203367–86 [99. 2022. Silkworm pupae as a future food with nutritional and medicinal benefits. Curr. Opin. Food Sci. 44:100818 [100. Schley L, Roper TJ. 2003. Diet of wild boar Sus scrofa in Western Europe, with particular reference to consumption of agricultural crops. Mamm. Rev. 33:143–56 [101. Schlüter 2017. Safety aspects of the production of foods and food ingredients from insects. Mol. Nutr. Food Res. 61:1600520 [102. Seabrooks L, Hu L. 2017. Insects: an underrepresented resource for the discovery of biologically active natural products. Acta Pharm. Sin. B 7:409–26 [103. 2021. Evaluation of fermented oat and black soldier fly larva as food ingredients in senior dog diets. Animals 11:3509 [104. . 2020. The unique antimicrobial peptide repertoire of stick insects. Dev. Comp. Immunol. 103:103471 [105. Sherman RA. 2009. Maggot therapy takes us back to the future of wound care: new and improved maggot therapy for the 21st century. J. Diabetes Sci. Technol. 3:336–44 [106. 2018. Impact of edible cricket consumption on gut microbiota in healthy adults, a double-blind, randomized crossover trial. Sci. Rep. 8:10762 [107. Sypniewski J, Kierończyk B, Benzertiha A, Mikołajczak Z, Pruszyńska-Oszmałek E et al. 2020. Replacement of soybean oil by Hermetia illucens fat in turkey nutrition: effect on performance, digestibility, microbial community, immune and physiological status and final product quality. Br. Poult. Sci. 61:3294–302 [108. 2019. Edible insects as a food source: a review. Food Prod. Process. Nutr. 1:8 [109. 2021. Edible insect farming as an emerging and profitable enterprise in East Africa. Curr. Opin. Insect Sci. 48:64–71 [110. Tao J, Li YO. 2018.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: 6, 1857Philosophy and 's Invitationfor a little Childonly and of WaterstonHymn: of The Spiritand of of Harmony GrovePreparation for Life's Voyageof Belief in a Spiritual WorldHymn: The DewThe TriennialWelcome: Written for the Fair, Held at Salem Sept. 4th, 1860The Child's reading the Memorial of BrowneHymn ("Not tears alone for natural grief")One generation passeth away, and another generation cometh: but the earth abideth for ever. Ecclesiastes 1:4What of Our Country? of not: for they that are with us are more than they that are with them. 2 Kings 6:16Hymn: Nature's Sympathy with FreedomChrist's The Garden: A ParaphraseSong: a on ImaginationSunset in Derby's Woodsare destroyed for lack of Knowledge. —Hosea 4:6Autumn FlowersHymn ("From out its large estate")The Poet's the Built by the Puritans in 1634Aurelia of : of Jonah ii. 9("I sought the flowers, but o'er them lay")Shall put on ImmortalityHymn: to 's ("A nobler unity, than that which came"): of LifeMan's Of PeaceHymn: Life of Humanityof Flora, On the grounds of R. the Unitarian Festival, in Faneuil Hall, May 26th 1863of LibertyHymn: Our Country's a Liveat the Church DoorHealth of Body dependent on the of the Mississippi Valleyof John Foster: "I Can Pray, And That's a Glorious Thing"Home and of Shakespeare's BirthdayHymn: of the Righteous EasyUntimely ArgumentsHymn ("In the shock of mighty armies")of : Christ's Invitation in theW. Felt Esq. New Type-of Libby Prison: Related by Capt. 's at the Eulogy on June 1st 1865Soul-SicknessSong of SpringSensibility to the Beauty and Fragrance of FlowersThe Word? of the : of Dew? Job 38:28"It is vain to say, that this is the country of the 'white man. ' It is the country of man. " 'O Lord, How Long?

Output: pass


Input: Claim: Personalized nutrition aims to tailor dietary advice based on genetic predispositions. [SEP] Text: All potential interactions between a specified set of food products and their ingredients (for example in an online shopping basket or identified through a barcode scan) and the patient’s combination of diseases and drugs were identified in real-time (taking <20 ms on a mobile phone) as shown in Figure 2. Figure 2: Process of generating recommendations for one or more selected food products by checking them for interaction potential and severity using the RACE runtime API to apply the user’s profile as an input state vector to the interactions nested array modelIf the food product has the potential to cause an interaction, personalized dietary advice can be offered to the user in the form of red/amber/green alerts and customizable “swaps” as shown in Figure 3. These swaps are alternative food products that are from the same product category (or supermarket shelf) but which do not share the potential risk for the drug: food or disease: food interactions of the originally chosen item for the user. The user can be rewarded for choosing such alternative healthier products as a way of gamifying the tool. Figure 3: (a) Highlighted foods showing the interaction potential with a user’s profile categorized from high risk/severity (red), medium risk/severity (amber) and no risk (green). (b) Suggested food swaps for the alcoholic drink productGiven the number and complexities of drug-disease-food interactions, there is often no product in a food subcategory that will be safe for everyone. To avoid suggesting products that will present a similar interaction risk for the user, for example, substituting kale for broccoli for a patient on warfarin, or smoked bacon for salami for a patient on isocarboxazid, every potential swap is tested against the user’s profile. This makes sure that all suggestions are appropriate alternatives for the user. this study over 500,000 drug-drug interactions and 136,784 drug-disease interactions were identified. When converted to a nonredundant database based on the drugs’ Ingredients (e. g. , acetylsalicylic acid is sold in Bayer Aspirin, Bayer Children’s Aspirin, Bufferin, Easprin, and Ecotrin) this was reduced to 9,526 drug-disease interactions representing interactions of 2,545 drugs’ active ingredients and 1,699 food ingredients.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Edible insects as a means to address global malnutrition and food insecurity issues. Food Qual. Saf. 2:117–26 [111. Tilami SK, Turek J, Červený D, Lepič P, Kozák P et al. 2020. Insect meal as a partial replacement for fish meal in a formulated diet for perch Perca fluviatilis. Turk. J. Fish. Aquat. Sci. 20:12867–78 [112. 2010. Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils. 39:117–21 [113. -Cairns M. 2019. Nutritional values and functional properties of house cricket (Acheta domesticus) and field cricket (Gryllus bimaculatus). Food Sci. Technol. Res. 25:597–605 [114. U. N. 2019. Prospects 2019: York: U. N. Dept. Econ. Soc. Aff. [115. van Huis A. 2013. Potential of insects as food and feed in assuring food security. Annu. Rev. Entomol. 58:563–83 [116. van Huis A. 2020. Nutrition and health of edible insects. Curr. Opin. Clin. Nutr. Metab. Care 23:228–31 [117. van Huis A, Dicke M, van Loon JJ. 2015. Insects to feed the world. J. Feed. 1:13–5 [118. van Huis A, van 2013. Edible Insects: for Food and Rome: FAO [119. van Itterbeeck J, Pelozuelo L. 2022. How many edible insect species are there? A not so simple question. Diversity 14:143 [120. Wade B, Keyburn A. 2015. The true cost of necrotic enteritis. 31:16–17 [121. . 2017. A comprehensive evaluation of replacing fishmeal with housefly (Musca domestica) maggot meal in the diet of Nile tilapia (Oreochromis niloticus): growth performance, flesh quality, innate immunity and water environment. Aquac. Nutr.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: 'Our Soldiers' upon the HeartNecessary for the Voyage of LifeSonnet ("I gazed upon the silent burial-ground")Nature's Help for the SoulNature a 's GroveOctober ("All day, admist the forests' splendor bright")and the Statesmanof Science, And of of the Springof TimeMotherHymn: of the SpiritHymn ("Admist the pastures green")of the come the Dead? 's TreasuresClose sectionSonnets on Reconstruction I. A Nation's. . IV. ("A unity complete, assured, and high") Reflections on the History of and the of at the Dedication of the of Science, Salem, Aug. 18, 1869have hoarded up treasure in the last days. —James 5:3Hymn: BodyHymn: of a Mother's surprises and the capture of capitals, are the events of a by-gone age. D'-'s SongsHymn, Sung at the of the Society, Salem. April 21, 1871of History Unlearnedof The GentilesTo a CloudThe Child's Dream of Reaching the 's of WinterInterpreting God's of MayOn the of the Christian Church, The Catholic, the Protestant, and the GreekO'Clock Bell"Are there Few that be Saved? " Luke 13:23the from Cook's Hill, in West PeabodySigns in the Natural WorldA Walk in Harmony Groveof Jabezof the FlowerDanvers Burying-GroundHymn ("He loveth not! he knows not God! ")Norman's RocksOn visiting the beautiful estate of H. H. Hunnewell, Esq. , at Wellesleyof a little child shall lead them. Isaiah XI. 6of RainOn the front of the house of the late Capt. Robert W. GouldOctober ("How beautiful the sight of woods still fair")Builders: the work of the late J. W. FosterBlessed are they that mourn: for they shall be comfortedThere shall be one Flock, one Shepherdof Salem: Illustrated by George M. WhiteColumbines and Anemonesin WinterReverenceInward PhenomenaTo the Memory of of the a Lichen from North Cape: Gathered by Mr. J. M.

Output: pass


Input: Claim: Personalized nutrition aims to tailor dietary advice based on genetic predispositions. [SEP] Text: All of these were incorporated into the knowledge model. This was implemented as a secure mobile phone application providing real-time advice based on a user’s profile. The resulting drug-disease-food interactions knowledge model and recommendations were reviewed initially using automated quality assurance protocols and then tested extensively on a virtual population of 10,000 complex (multi-morbid and polypharmaceutical) patients with a randomized but accurately distributed set of morbidities. This population was constructed with the UK normal distribution of sex, age, diseases (with stage and severity) and prescriptions (following NICE standard clinical pathway guidelines for their assigned diseases). precisionlife DIET accurately identified all the “obvious” first-order reported drug: food interactions, for example, grapefruit for simvastatin users, as well as most for some foods with obfuscated or ambiguous ingredients. It also provided accurate warnings in a number of cases where the interactions of multiple food ingredients, drugs and/or disease processes could result in a problem for the user, for example, hypocalcemia for patients with chronic kidney disease on certain diuretics. It was necessary to implement a refinement to restrict some of the interaction warnings based on the amount of a particular ingredient in foods. For example, wine-based vinegars are commonly used as flavorings, but the proportion of alcohol is small (<2% by volume) and the volume used is typically very small (<10 mL). This poses a negligible risk in most cases even where alcohol is contraindicated. The issue was overcome by restricting the recommendations based only on ingredients in the first five positions on the label (which are ordered by volume). same engine can be used for wellness applications to maintain a healthy diet. This may include nutritional guidelines with specific targets for nutritional components. It may also be used to enable people to achieve certain health goals, for example, the incorporation of additional folic acid into the diet of a newly pregnant woman or management of GI and total carbohydrates in a prediabetic person. Information on 457 allergen labels and 19,612 pharmacogenetic interactions is also being included in more recent versions (e. g. , for future use with consumer or clinical genomics profiles once they become available). study has shown that it is possible to provide accurate personalized dietary advice to complex patients wholly on their own mobile device in real-time and without needing to maintain or even see their personal medical data.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: 23:983–93 [122. 2021. Nutritional and microbial quality of extruded fish feeds containing black soldier fly (Hermetia illucens L) larvae meal as a replacement for fish meal for tilapia (Oreochromis niloticus) and catfish (Clarias gariepinus). J. Appl. Aquac. 34:41036–52 [123. . 2009. Anticancer effects of phytosterols. Eur. J. Clin. Nutr. 63:813–20 [124. . 2021. Nutritional, functional, and allergenic properties of silkworm pupae. Food Sci. Nutr. 9:4655–65 [125. 2020. Growth performance, immunity and intestinal microbiota of swamp eel (Monopterus albus) fed a diet supplemented with house fly larvae (Musca domestica). Aquac. Nutr. 26:693–704 [126. 2014. Effects of antimicrobial peptides in nursery diets on growth performance of pigs reared on five different farms. Livest. Sci. 167:206–10 [127. . 2021. Using edible insects in the production of cookies, biscuits, and crackers: a review. Biol. Life Sci. Forum 6:80 [128. . 2014. Insect antimicrobial peptides and their applications. Appl. Microbiol. Biotechnol. 98:5807–22 [129. 2012. Effects of dietary supplementation of antimicrobial peptide-A3 on growth performance, nutrient digestibility, intestinal and fecal microflora and intestinal morphology in weanling pigs. Anim. Feed Sci. Technol. 177:98–107 [130. 2014. Effects of dietary supplementation of synthetic antimicrobial peptide-A3 and P5 on growth performance, apparent total tract digestibility of nutrients, fecal and intestinal microflora and intestinal morphology in weanling pigs. Livest. Sci. 159:53–60 [131. 2013. Effects of dietary supplementation with antimicrobial peptide-P5 on growth performance, apparent total tract digestibility, faecal and intestinal microflora and intestinal morphology of weanling pigs. J. Sci. Food Agric. 93:587–92 [132. 2019.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: Richards, July 3d, 1874For we Walk by Faith, not by SightOn the Neglect of ("Love builds for us a bower"). Felton, Esq. , of BrookfieldOn the Increase of Crime since the of ManSailing on Cakes of Ice in the North River("Not unto men alone has come")of the First ChristiansOn the in New Grenadain Bloomthe Graves of Hawthorne and Thoreauthe Falls of Niagara, as Photographed by George BarkerKnowledge and TruthMt. Shasta: A Painting, by H. O. YoungSong: I Love the LightUs of Time and its DurationTake ye heed, watch and pray: for ye know not when the time is. Mark 13:33in PeabodyMan's Need of a Spiritual BirthOn some Eternals from a friend's gardenHymn: of the Righteous"Tuesday night, the schooner Weaver, of Glen Creek, N. J. , went to pieces near Sandy Hook, and her entire crew were lost": Transcript, March 22dof the at PhiladelphiaEvolutionCapt. Samuel CookOn the Beautiful Roses, In front of the Mansion of John Hodges, Esq. waiting at the Pasture GateSong: DayOn some blue and golden Columbines from Pike's Peak, ColoradoDesert of : at Seathe Reconciling Powera Day of FreedomHymn: Reflections at the Close of the Yearthe Clock Strike, in Harmony GroveThe Indians' Belief in a a Visible ObjectLove that Casts out FearMarks on our HillsState of the Wicked and its DurationFaith in the Resurrection ConfirmedSpring and Summer Flowersof the ColumbineMan's AccountabilityHymn: of of by MobsThe Barberry-? Know Thyself: Suggested by hearing Dr. A. E. Miller's Lectures on the "Agriculture the Source of Individual and National Prosperity"—Anne PrattPleasure ("With business haste, or with a worldly mind").

Output: pass


Input: Claim: Personalized nutrition aims to tailor dietary advice based on genetic predispositions. [SEP] Text: Close navigation menu of Nutrition and Nutrition: Translating Nutrigenetic/into Edited by A. P. Simopoulos; A. P. for other works by this author on: PubMed 10. 1159/isbn. 978-3-8055-9428-8 Status: Available ISBN electronic: 978-3-8055-9428-8 ISBN print: 978-3-8055-9427-1 Subject Area: Genetics Nutrition and Dietetics Series: of Nutrition and date: 2010 Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system. This publication contains selected papers from the ‘3rd Congress of the of Nutrigenetics/Nutrigenomics’ held in Bethesda, Md. , in October 2009. The contributions address frontiers in nutrigenetics, nutrigenomics, epigenetics, transcriptomics as well as non-coding RNAs and posttranslational gene regulations in various diseases and conditions. In addition to scientific studies, the challenges and opportunities facing governments, academia and the industry are included. Everyone interested in the future of personalized medicine and nutrition or agriculture, as well as researchers in academia, government and industry will find this publication of the utmost interest for their work. ‹ › 10. 1159/000314516 Published: 2010 Subject Area: Genetics Nutrition and Dietetics Series: of Nutrition and Tools Split-2010. "Toxicogenomics and Studies of of Dietary Components", Personalized Nutrition: Translating Nutrigenetic/into Dietary Guidelines, A. P. Simopoulos, J. A. citation file: Ris (Zotero) toolbar search search input Search input auto suggest filter your search 2010License DisclaimerThis 4. 0 (CC BY-NC-ND). Usage and distribution for commercial purposes as well as any distribution of modified material requires written permission. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Use of Hermetia illucens larvae as a dietary protein source: effects on growth performance, carcass traits, and meat quality in finishing pigs. Meat Sci. 158:107837 [133. 2020. Evaluation of full-fat Hermetia illucens larvae meal as a fishmeal replacement for weanling piglets: effects on the growth performance, apparent nutrient digestibility, blood parameters and gut morphology. Anim. Feed Sci. Technol. 264:114431 [134. . 2019. Hermetia illucens larvae as a potential dietary protein source altered the microbiota and modulated mucosal immune status in the colon of finishing pigs. J. Anim. Sci. Biotechnol. 10:50 [135. 2020b. Hermetia illucens larvae as a fishmeal replacement alters intestinal specific bacterial populations and immune homeostasis in weanling piglets. J. Anim. Sci. 98:skz395 [136. . 2015. Effects of dietary fats rich in lauric and myristic acid on performance, intestinal morphology, gut microbes, and meat quality in broilers. Poult. Sci. 94:102404–13 [137. . 2022. Nutritional composition, health benefits, and application value of edible insects: a review. Foods 11:3961 [138. . 2022. Silkworm pupae: a functional food with health benefits for humans. Foods 11:1594 [10. 1146/annurev-ento-020123-013621 Dietary and of Edible Insects: A of Entomology 69, 303 (2024);content/journals/10. 1146/annurev-ento-020123-013621content/journals/10. 1146/annurev-ento-020123-013621 Data & Media loading. . . Figure 1 (PDF). 10. 1146/annurev-ento-020123-013621 dcterms_title,dcterms_subject,pub_keyword -contentType:Journal -contentType:Contributor -contentType:Concept -contentType:Institution 4 4 1. Al-Saggaf MS. 2021. Formulation of insect chitosan stabilized silver nanop2. örlein D. 2019.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: Close sectionO heaven born muse! inspire my humble layThe earth is parched with heat, flowers droop and dieLines, Written on Reading Stuart's Account of of Slaves in CharlestonLines on Mount AuburnLines suggested by hearing the beach, at F. Peabody's Mills, South SalemHast thou ever heard the voice of nature'Ambitione inani pectus caret'What more delightful than to wander forthA by Mr J. Very, to be Sung at the Class-Supper of the of 1834Death of ("Goddess of pleasure, where thy golden car? ")Give me an eye, that manly deedsI saw a child, whose eyes had never drankcold thy lips my gentle boySpring ('Look! Winter now in trembling haste')The morn may lend its golden smile— On the Death of His FriendNorth RiverEheu! fugaces, Posthume, Posthume, Labuntur anniThe Humming-BirdNature ('I love to sit on the green hill's side')ReligionA Withered Leaf—seen on a Poet's ('Soon the silver chord is broken')Memory ('Soon the waves, so lightly bounding')'s of of 22d, 1836Song: For the of the of Harvard University, 1836's Dream: A BalladI murmur not though hard the lotFlowerThe moon was shining on the deckHome of my youth! Where first my lot was castHaunts of my youth farewell! A while I leaveand ('I love thee when thy swelling buds appear')('Nature, my love for thee is deeper far')of GodThe Wind-('Thou who keepst us each together')The Stranger's 'we live, & move, & have our being'and ('Father! thy wonders do not singly stand')The Slavefrom ('The Word!

Output: pass


Input: Claim: Personalized nutrition aims to tailor dietary advice based on genetic predispositions. [SEP] Text: AbstractPersonalized nutrition has the potential to enhance individual health control. It could be seen as a means to strengthen people’s autonomy as they learn more about their personal health risks, and receive dietary advice accordingly. We examine in what sense personalized nutrition strengthens or weakens individual autonomy. The impact of personalized nutrition on autonomy is analyzed in relation to responsibility and trustworthiness. On a societal level, individualization of health promotion may be accompanied by the attribution of extended individual responsibility for one’s health. This constitutes a dilemma of individualization, caused by a conflict between the right to individual freedom and societal interests. The extent to which personalized nutrition strengthens autonomy is consequently influenced by how responsibility for health is allocated to individuals. Ethically adequate allocation of responsibility should focus on prospective responsibility and be differentiated with regard to individual differences concerning the capacity of adults to take responsibility. The impact of personalized nutrition on autonomy also depends on its methodological design. Owing to the complexity of information received, personalized nutrition through genetic testing (PNTGT) is open to misinterpretation and may not facilitate informed choices and autonomy. As new technologies, personalized nutrition and PNTGT are subject to issues of trust. To strengthen autonomy, trust should be approached in terms of trustworthiness. Trustworthiness implies that an organization that develops or introduces personalized nutrition can show that it is competent to deal with both the technical and moral dimensions at stake and that its decisions are motivated by the interests and expectations of the truster. Similar content being viewed by others (Bio)ethical Aspects of Personalised Medicine: Revealing an “Inconvenient Truth”? 2. 7 % to be precise). In terms of autonomy, the risk of misinterpreting such information is problematic. Someone may either underestimate the risk and follow a potentially dangerous diet or, more likely, he or she may overestimate it. This results not only in unnecessary anxiety, but also in restricting people’s lifestyle without valid reasons. For example, someone may restrict himself to a certain diet that does not contain the foods he likes most, although the foods he denies himself would have negligible health effects. Trust and trustworthinessSince the individual receives personal information on health risks and dietary advice, autonomy may be strengthened. However, owing to the complexity of information given to the individual through PNTGT or personalized nutrition in general, informed choice becomes difficult and autonomy may also be weakened. To give helpful individual health advice presupposes that relevant and sufficient knowledge is made accessible.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Do dietary soy alternatives lead to pork quality improvements or drawbacks? A look into microalga and insect protein in swine diets. Meat Sci. 153:26–34 [3. Ao X, Kim IH. 2019. Effects of dietary dried mealworm (Ptecticus tenebrifer) larvae on growth performance and nutrient digestibility in weaning pigs. Livest. Sci. 230:103815 [4. 2013. Techniques for extraction of bioactive compounds from plant materials: a review. J. Food Eng. 117:426–36 [5. . 2015. Insect consumption to address undernutrition, a national survey on the prevalence of insect consumption among adults and vendors in Laos. 10:e0136458 [6. Benzertiha A, Kierończyk B, Rawski M, Kołodziejski P, Bryszak M, Józefiak D. 2019. Insect oil as an alternative to palm oil and poultry fat in broiler chicken nutrition. Animals 9:116 [7. Benzertiha A, Kierończyk B, Rawski M, Mikołajczak Z, Urbański A et al. 2020. Insect fat in animal nutrition—a review. Ann. Anim. Sci. 20:41217–40 [8. Bertola M, Mutinelli F. 2021. A systematic review on viruses in mass-reared edible insect species. Viruses 13:2280 [9. Beynen AC. 2020. Hypoallergenic cat foods. Dier-en-Arts 10:255–57 [10. Ørnsrud. 2019. Replacing fish meal with insect meal in the diet of Atlantic salmon (Salmo salar) does not impact the amount of contaminants in the feed and it lowers accumulation of arsenic in the fillet. Food Addit. Contam. A 36:81191–205 [11. 2020. Effects of dietary Hermetia illucens meal inclusion on cecal microbiota and small intestinal mucin dynamics and infiltration with immune cells of weaned piglets. J. Anim. Sci. Biotechnol. 11:64 [12. 2019.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: it cannot fail; it ever speaks')Worship ("There is no worship now—the idol stands")of Lifeof the ("There is a winter in the godless heart")'s and the at ('I saw the city, 'twas not built by hands')The CrossNature ('Nature would speak through her first master man')and meat and drinkForgive me my trespassesin HeartThe ComplaintWhither shall I go from thy Spiritshall be LastThe LaborerThy Brother's of are passed away('They love me not, who at my table eat')The CityThe RoseFaith ('There is no faith; the mountain stands within')The JewSpring ('The stem that long has borne the wintry blast')and The EndNature ('The bubbling brook doth leap when I come by')! The Sign('I too will wait with thee returning spring')('Father! help them who walk in their own light')notice other days were pages givenThe CrocusThe PlantI am the WayThe kingdom of within you('There is no sound but thou dost hear my voice')The PreacherCome unto meFlee to the mountainsBlessed are they that mournFaith ('Hast thou but faith thou shalt the mountain bid')Redeeming the TimeTis FinishedEffortTo the pure all things are pureThe TaskSpring ('I have not lived the flesh has hedged me in')('The plant it springs it rears its drooping head')('Come thou and labor with me I will give')('The words I give thee they are not thine own')Joy ('The joy Thou giv'st no man can take away')HopeReliefJoy ('Thou hast a moon for every cloudy night')('I come the rushing wind that shook the place')of is every one who is born of the spiritThe SeedI am the Light of the the Bread of shall all the tribes of the earth mournRepent for the kingdom of Heaven is at handthe you is born a SaviourThe RedeemedHallowed be they NameTo him who overcomethof the Templeof as the World giveth('Open our eyes that we the world may see')Thy Father's HouseJacob's Wellof ('The voice that speaks when thou art in thy tomb')and ('Why are thou not awake my son? ')('not visit me?

Output: pass


Input: Claim: Personalized nutrition aims to tailor dietary advice based on genetic predispositions. [SEP] Text: But owing to the complexity of information with regard to personalized nutrition (and many other medical techniques), each individual can be informed only to a certain degree. Therefore, information requires a certain amount of trust in suppliers of personalized nutrition. Linked to the question of autonomy as a value at stake is therefore the question of how personalized nutrition affects public trust in personalized nutrition and food products. Personalized nutrition is often developed as a way to give control to individuals to deal with health risks. At the same time, both health information and the food sector become more complex. As a consequence, an individual cannot but rely on many others. As a consumer, one is no longer able to assess personally all the risks and benefits of any particular product. Consequently, we are all necessarily part of complex webs of trust relationships, linking the person who trusts (the truster) to the person or institution whom he or she trusts (the trustee) (Meijboom 2007). Trust is essential for the food and health sectors because it is an attitude that is relevant if one is confronted with uncertainty or lack of personal control. The attitude of trust is a way of “managing uncertainty” (Becker 1996). In trusting, one acts “as if” certain possible states of affairs will not occur (Lewis and Weigert 1985). This is not an escape into some make-believe world but is based on an assessment of the person or institution that one has to rely on. Personalized nutrition offerings are based on claims. These are related to information given on the health effect of specific nutrients for a certain individual, the method of how personal health data is processed into individually tailored nutritional advice, or recommended food supplements. The consumer who has no possibility to entirely verify the scientific basis of this procedure and associated claims has to decide, if the company or institution offering the service seems trustworthy or not. Utterly the trustworthiness of a company or institution offering personalized nutrition services depends on how personal health data are handled and whether the procedure applied to create value for the consumer is convincing. Problems of trust may be dealt with by striving to reduce the need for trust, that is, reducing the uncertainty and/or giving the truster personal control. From this perspective, personalized nutrition can contribute to a reduction in the need to trust.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: de Gier S, Verhoeckx K. 2018. Insect (food) allergy and allergens. Mol. Immunol. 100:82–106 [24. . 2020. New perspectives in food allergy. Int. J. Mol. Sci. 21:1474 [25. -Sosa DA. 2020. Consumers' perception of bakery products with insect fat as partial butter replacement. Food Qual. Prefer. 79:103755 [26. . 2019. Antioxidant activities in vitro of water and liposoluble extracts obtained by different species of edible insects and invertebrates. Front. Nutr. 6:106 [27. . 2010. as Food: Back! ! Bangkok: FAO Reg. Off. Asia Pac. [28. FAO. 2017. of Food and Agriculture—Trends and Challenges Rome: FAO [29. . 2009. Research and utilization of medicinal insects in China. Entomol. Res. 39:313–16 [30. . 2016. Beeswax: a minireview of its antimicrobial activity and its application in medicine. Asian Pac. . J. Trop. Med. 9:839–43 [31. Gajski G, Garaj-Vrhovac V. 2013. Melittin: a lytic peptide with anticancer properties. Environ. Toxicol. Pharmacol. 36:697–705 [32. 2014. Enantiomerization and enantioselective bioaccumulation of metalaxyl in Tenebrio molitor larvae. Chirality 26:88–94 [33. 2019. Quality and consumer acceptance of meat from rabbits fed diets in which soybean oil is replaced with black soldier fly and yellow mealworm fats. Animals 9:629 [34. Gasco L, Finke M, van Huis A. 2018. Can diets containing insects promote animal health? . J. Feed. 4:1–4 [35. 2016. Tenebrio molitor meal in diets for European sea bass (Dicentrarchus labrax L. ) juveniles: growth performance, whole body composition and in vivo apparent digestibility. Anim. Feed Sci. Technol. 220:34–45 [36. Gasco L, Józefiak A, Henry M. 2020.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: ')-ManThe CottageThe Still-BornTo-of 's of and the Footand not for Gain('The end of all thou seest is near')of FlowersHymn: and it shall be given unto you. from WithinThou know'st not what thy Lord will sayof the JustDeathThe Birth-Day of the SoulHiveTime's Houseand the BirdFaith and Light('where is it? hath it voice')('Stay where thou art, thou need'st not further go')'s Island Lightof Godof the BooksThe Robin's ('Tis all a great show')on Reading the Death of Rev. Henry Ware, Jr. BrightGod's at the ('There are towers; where they are')ye sow, so shall ye reap's RetortThe WidowImpatienceAbdolonymus—'s by FaithSalem ("Boast not, my native spot, thy sons were first")Spring in the SoulNature's InvitationChrist's CompassionHymn: Nevertheless, when the Son of Man cometh, shall he find faith on the earth? :8of 'to LiveThe Indian's the late in 's : Suggested by an EngravingThoughts and DesiresHymn ('As by the quickening breath of Spring')The Soul's : of the Rev. James Flint, D. D. , On reading his Collection of on the of J. Esq. July 22d, 1853the at the Thompson Jubilee, at Barre, Jany. 12, 1854: Sung at the Celebration of the Fourth of July, in Salem, 1854? To the Memory of the Rev. James Flint, D. D. and WorldlyHymn: So also will God, through Jesus, bring with him them who sleep'Blessed are they that mourn: for they shall be comforted' Math. 5:4To the Memory of the Rev. of -cleave not to the things of earth's the Rev. C. H. A. Dall, in IndiaHymn: Sung at the Dedication of Plummer Hall, Salem, Oct.

Output: pass


Input: Claim: Personalized nutrition aims to tailor dietary advice based on genetic predispositions. [SEP] Text: On the one hand, improved knowledge of human genetics and further understanding of its relationship with certain ailments may help to translate uncertainties into risks that can be calculated by individuals. The occurrence of certain illnesses is no longer a black box but can be explained or even prevented with the help of knowledge about a person’s genetic makeup. On the other hand, dietary advice may give certain levels of control to individuals. Personalized nutrition can provide tools to make autonomous decisions on how to deal with health risks. Consequently, it can reduce the need to trust. Even though personalized nutrition can help individuals achieve better control over their health, it also presupposes trust. The obvious reason for trust is the high-tech character of tailor-made dietary advice. To use these services or products, which are at the interface between food and health, most individuals have to rely on many experts in the fields of human genetics, human health, and food. Only if one trusts the outcome of genetic tests, the interpretation by experts, and the adequacy of the proposed dietary advice is one in a position to better control one’s own health. On top of this, personalized nutrition may extend the realm in which trust is required. In most situations, people who are offered personalized nutrition have not noticed any health risk. They did not consider their health status in terms of trust until the information on genetic risks alerted them. Therefore, the range of situations in which one has to trust others will be extended (Meijboom 2007). Finally, trust may become complicated as a result of different patterns and routines in the food and health sectors. In each sector, one knows what one may expect in another. If personalized nutrition brings these sectors together, a reflection on mutual expectations is necessary to establish trustful relationships. Further research on regulative challenges of personalized nutrition products and services on the borderline between food and medicine is called for (Ahlgren et al. 2013). Personalized nutrition requires trustworthiness to strengthen autonomyThe claim that trust is needed to make personalized nutrition operational can be easily understood as the problem of individual consumers or patients. It is necessary to rely on others in order to make full use of the promising characteristics of the various products. This, however, is too easy an approach for problems of trust. To make personalized nutrition strengthen autonomy, we should address questions of trust by starting with trustworthiness. There are three reasons for this step.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Beyond the protein concept: health aspects of using edible insects on animals. J. Feed. 7:715–41 [37. 2010. Immunity and other defenses in pea aphids, Acyrthosiphon pisum. Genome Biol. 11:R21 [38. . 2015. Regulating edible insects: the challenge of addressing food security, nature conservation, and the erosion of traditional food culture. Food Secur. 7:739–46 [39. 2021. Effect of heat, enzymatic hydrolysis and acid-alkali treatment on the allergenicity of silkworm pupa protein extract. Food Chem. 343:128461 [40. Herrero J, García-Serrano A, Couto S, Ortuño VM, García-González R. 2006. Diet of wild boar Sus scrofa L. and crop damage in an intensive agroecosystem. Eur. J Wildl. Res. 52:245–50 [41. 2021. Black soldier fly larvae meal and fat can completely replace soybean cake and oil in diets for laying hens. Poult. Sci. 100:101034 [42. -Algoed M, et al. 2016. Pesticide contamination of Tenebrio molitor (Coleoptera: Tenebrionidae) for human consumption. Food Chem. 201:264–69 [43. 2019. Effect of mealworm (Tenebrio molitor L. ) larvae meal on amino acid composition of gilthead sea bream (Sparus aurata L. ) and rainbow trout (Oncorhynchus mykiss W. ) fillets. Aquaculture 513:734403 [44. . 2021. Growth of yellowtail (Seriola quinqueradiata) fed on a diet including partially or completely defatted black soldier fly (Hermetia illucens) larvae meal. Insects 12:722 [45. Imathiu S. 2020. Benefits and food safety concerns associated with consumption of edible insects. NFS J. 18:1–11 [46. 2009. The Kunitz-like modulatory protein haemangin is vital for hard tick blood-feeding success. PLOS Pathog 5:e1000497 [47. . 2016.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: 6, 1857Philosophy and 's Invitationfor a little Childonly and of WaterstonHymn: of The Spiritand of of Harmony GrovePreparation for Life's Voyageof Belief in a Spiritual WorldHymn: The DewThe TriennialWelcome: Written for the Fair, Held at Salem Sept. 4th, 1860The Child's reading the Memorial of BrowneHymn ("Not tears alone for natural grief")One generation passeth away, and another generation cometh: but the earth abideth for ever. Ecclesiastes 1:4What of Our Country? of not: for they that are with us are more than they that are with them. 2 Kings 6:16Hymn: Nature's Sympathy with FreedomChrist's The Garden: A ParaphraseSong: a on ImaginationSunset in Derby's Woodsare destroyed for lack of Knowledge. —Hosea 4:6Autumn FlowersHymn ("From out its large estate")The Poet's the Built by the Puritans in 1634Aurelia of : of Jonah ii. 9("I sought the flowers, but o'er them lay")Shall put on ImmortalityHymn: to 's ("A nobler unity, than that which came"): of LifeMan's Of PeaceHymn: Life of Humanityof Flora, On the grounds of R. the Unitarian Festival, in Faneuil Hall, May 26th 1863of LibertyHymn: Our Country's a Liveat the Church DoorHealth of Body dependent on the of the Mississippi Valleyof John Foster: "I Can Pray, And That's a Glorious Thing"Home and of Shakespeare's BirthdayHymn: of the Righteous EasyUntimely ArgumentsHymn ("In the shock of mighty armies")of : Christ's Invitation in theW. Felt Esq. New Type-of Libby Prison: Related by Capt. 's at the Eulogy on June 1st 1865Soul-SicknessSong of SpringSensibility to the Beauty and Fragrance of FlowersThe Word? of the : of Dew? Job 38:28"It is vain to say, that this is the country of the 'white man. ' It is the country of man. " 'O Lord, How Long?

Output: pass


Input: Claim: The field of nutrigenomics explores the interaction between diet and genes. [SEP] Text: BackgroundNutrigenomics defines the nutrient-gene interactions in a host and at present includes not only nutrient-gene interactions but also nutrient-epigenetic, nutrient-proteomic, and nutrient-metabolomic interactions as well as host-diet-microbiome interactions [1]. In this sense, nutrigenomic research is located on the intersection between diet, health, and genomics [2, 3]. Drosophila melanogaster is a model organism essentially applied in genetic research that brings promising advantages into studying preclinical nutrigenomics. Its evolutionary biology significantly contributes to the understanding of gene expression and development in humans, as its genome conserves approximately 60% of genes that are related with DNA mutations, amplifications, or deletions in a diverse set of human diseases [4, 5]. Its genome encodes ca. 18,000 genes located on four homologous pairs of chromosomes, while only three of them hold the main part of the genome. Flies and mammalian species normally share about 40% of the nucleotide and protein sequences in their homologs; in some conserved functional domains, it can be more than 90% [6, 7]. Chromosomal deletions and mutations have been generated for the production of Drosophila melanogaster mutants, targeting more than 80% of its genome [8]. Beside its well-characterized genome and the good availability of mutant and transgenic flies, other advantages including a rapid life cycle (12 days for the succession of egg, maggot, pupa, and imago), a short life span (around 70–80 days), a small size (possibility of breeding hundreds of individuals in small bottles), and a relatively easy generation of mutant animals in comparison to other organisms make Drosophila melanogaster an excellent model organism in nutrigenomic research. Particularly, due to the presence of a fat body with adipocytes and conserved metabolic pathways involved in fat metabolism and insulin signaling, Drosophila melanogaster has been extensively used to investigate obesity-associated diseases, including cardiovascular dysfunction or cancer [9,10,11].

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Effect of dried mealworm larvae probiotics on quality and oxidative stability of meat in broilers. J. Poult. Sci. 4:462–67 [48. . 2008. Anaphylactic shock caused by silkworm pupa consumption in China. Allergy 63:1407–8 [49. . 2008. Protein content and amino acid composition in grains of wheat-related species. Agric. Sci. China 7:3272–79 [50. . 2016. Supplementation of dried mealworm (Tenebrio molitor larva) on growth performance, nutrient digestibility and blood profiles in weaning pigs. Asian-Aust. . J. Anim. Sci. 29:979–86 [51. 2009. Commercialization of insects and their products. Encyclopedia of é 220–27. Cambridge, MA: Academic [52. . 2022. Characteristics and nutritional value of silkworm (Bombyx mori) pupae-fortified chicken bread spread. Sci. Rep. 12:1492 [53. 2015. African edible insects for food and feed: inventory, diversity, commonalities and contribution to food security. J. Feed 2:103–19 [54. Kierończyk B, Rawski M, Józefiak A, Mazurkiewicz J, Świątkiewicz S et al. 2018. Effects of replacing soybean oil with selected insect fats on broilers. Anim. Feed Sci. Technol. 240:170–83 [55. Kierończyk B, Rawski M, Mikołajczak Z, Homska N, et al. 2022. Available for millions of years but discovered through the last decade: insects as a source of nutrients and energy in animal diets. Anim. Nutr. 11:60–79 [56. Kierończyk B, Rawski M, Mikołajczak Z, Leciejewska N, Józefiak D. 2021. Hermetia illucens fat affects the gastrointestinal tract selected microbial populations, their activity, and the immune status of broiler chickens. Ann. Anim. Sci. 22:2663–75 [57.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: 'Our Soldiers' upon the HeartNecessary for the Voyage of LifeSonnet ("I gazed upon the silent burial-ground")Nature's Help for the SoulNature a 's GroveOctober ("All day, admist the forests' splendor bright")and the Statesmanof Science, And of of the Springof TimeMotherHymn: of the SpiritHymn ("Admist the pastures green")of the come the Dead? 's TreasuresClose sectionSonnets on Reconstruction I. A Nation's. . IV. ("A unity complete, assured, and high") Reflections on the History of and the of at the Dedication of the of Science, Salem, Aug. 18, 1869have hoarded up treasure in the last days. —James 5:3Hymn: BodyHymn: of a Mother's surprises and the capture of capitals, are the events of a by-gone age. D'-'s SongsHymn, Sung at the of the Society, Salem. April 21, 1871of History Unlearnedof The GentilesTo a CloudThe Child's Dream of Reaching the 's of WinterInterpreting God's of MayOn the of the Christian Church, The Catholic, the Protestant, and the GreekO'Clock Bell"Are there Few that be Saved? " Luke 13:23the from Cook's Hill, in West PeabodySigns in the Natural WorldA Walk in Harmony Groveof Jabezof the FlowerDanvers Burying-GroundHymn ("He loveth not! he knows not God! ")Norman's RocksOn visiting the beautiful estate of H. H. Hunnewell, Esq. , at Wellesleyof a little child shall lead them. Isaiah XI. 6of RainOn the front of the house of the late Capt. Robert W. GouldOctober ("How beautiful the sight of woods still fair")Builders: the work of the late J. W. FosterBlessed are they that mourn: for they shall be comfortedThere shall be one Flock, one Shepherdof Salem: Illustrated by George M. WhiteColumbines and Anemonesin WinterReverenceInward PhenomenaTo the Memory of of the a Lichen from North Cape: Gathered by Mr. J. M.

Output: pass


Input: Claim: The field of nutrigenomics explores the interaction between diet and genes. [SEP] Text: Changes in triglyceride levels and lipid storage induced by the intake of high-fat and high-sugar diets have been related with genetic variations in both genes of the insulin/insulin-like growth factor signaling (IIS) and the target of rapamycin (TOR) signaling pathway [12, 13]. The fruit fly also resembles a good model to study different tissues or organs due to its mammalian-like anatomy and equivalent functions. The present review provides information on the fruit fly’s morphology and anatomy with a special focus on the gastrointestinal system and the gut microbiota, key facts in nutrigenomics studies. Additionally, it gives insights into the different methods applied in nutrigenomics and their utilization in Drosophila melanogaster. Drosophila melanogaster—morphologyDrosophila melanogaster presents different morphology traits as a product of natural selection. These differences are generally associated with gene mutations referring to single phenotypes [14]. Mutation markers indicating differences in bristles, wings, appendages, eye shapes, and colors and body sizes have been collected by FlyBase (www. flybase. org), providing accurate information about its location in the chromosomes. Environmental factors, such as nutrition, temperature, or crowding, have been reported to be responsible for morphological traits, in particular, body size variations, and have been connected to quantitative trait loci (QTL) mapping on the third chromosome while no QTLs or QTLs with minor effects on these factors have been detected in the other major chromosomes [14]. The time for fly development, also known as the fruit fly life cycle, varies within different environmental conditions. Generally, the development of new flies takes around 10 days at 25 °C with four developmental stages: the embryo, larvae (three different stages), pupal stage, and imago stage. The adult flies reach sexual maturity 2–4 days after eclosion. According to a typical insect morphology, the adult fruit fly body is divided into three parts: head, thorax, and abdomen. In the head, there are several sensory organs, noting the compound eyes, containing primary pigments being characteristic for different mutants, and the proboscis, representing the gustatory organ for food detection, taste, and intake, which could be extended and retracted and pumps the food into the gut.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Kierończyk B, Rawski M, Mikołajczak Z, Szymkowiak P, Stuper-Szablewska K, Józefiak D. 2023. Black soldier fly lava fat in broiler chicken diets affects breast meat quality. Animals 13:71137 [58. Kierończyk B, Rawski M, Pawełczyk P, Różyńska J, et al. 2018. Do insects smell attractive to dogs? A comparison of dog reactions to insects and commercial feed aromas—a preliminary study. Ann. Anim. Sci. 18:3795–800 [59. . 2016. Pre-treated mealworm larvae and silkworm pupae as a novel protein ingredient in emulsion sausages. Innov. Food Sci. Emerg. Technol. 38:116–23 [60. . 2017. Sensory profiles of protein-fortified kefir prepared using edible insects (silkworm pupae, Bombyx mori): a preliminary study. J. Dairy Sci. Biotechnol. 35:262–65 [61. . 2020. The produced mealworm meal through organic wastes as a sustainable protein source for weanling pigs. J. Anim. Sci. Technol. 62:365–73 [62. Kouřimská L, Adámková A. 2016. Nutritional and sensory quality of edible insects. NFS J. 4:22–26 [63. Kozłowski K, Ognik K, Stępniowska A, Juśkiewicz J, Zduńczyk Z et al. 2021. Growth performance, immune status and intestinal fermentative processes of young turkeys fed diet with additive of full fat meals from Tenebrio molitor and Hermetia illucens. Anim. Feed Sci. Technol. 278:114994 [64. Kröger T, Dupont J, Büsing L, Fiebelkorn F. 2022. Acceptance of insect-based food products in Western societies: a systematic review. Front. Nutr. 8:759885 [65. 2015. Biomedical applications of silkworm pupae proteins. of Natural Proteins: Era in 41–49.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: Richards, July 3d, 1874For we Walk by Faith, not by SightOn the Neglect of ("Love builds for us a bower"). Felton, Esq. , of BrookfieldOn the Increase of Crime since the of ManSailing on Cakes of Ice in the North River("Not unto men alone has come")of the First ChristiansOn the in New Grenadain Bloomthe Graves of Hawthorne and Thoreauthe Falls of Niagara, as Photographed by George BarkerKnowledge and TruthMt. Shasta: A Painting, by H. O. YoungSong: I Love the LightUs of Time and its DurationTake ye heed, watch and pray: for ye know not when the time is. Mark 13:33in PeabodyMan's Need of a Spiritual BirthOn some Eternals from a friend's gardenHymn: of the Righteous"Tuesday night, the schooner Weaver, of Glen Creek, N. J. , went to pieces near Sandy Hook, and her entire crew were lost": Transcript, March 22dof the at PhiladelphiaEvolutionCapt. Samuel CookOn the Beautiful Roses, In front of the Mansion of John Hodges, Esq. waiting at the Pasture GateSong: DayOn some blue and golden Columbines from Pike's Peak, ColoradoDesert of : at Seathe Reconciling Powera Day of FreedomHymn: Reflections at the Close of the Yearthe Clock Strike, in Harmony GroveThe Indians' Belief in a a Visible ObjectLove that Casts out FearMarks on our HillsState of the Wicked and its DurationFaith in the Resurrection ConfirmedSpring and Summer Flowersof the ColumbineMan's AccountabilityHymn: of of by MobsThe Barberry-? Know Thyself: Suggested by hearing Dr. A. E. Miller's Lectures on the "Agriculture the Source of Individual and National Prosperity"—Anne PrattPleasure ("With business haste, or with a worldly mind").

Output: pass


Input: Claim: The field of nutrigenomics explores the interaction between diet and genes. [SEP] Text: Healthy diet and proper nutrition are basic necessity of life and play a key role in preventing diseases. Nutrigenomics (NG) is an emerging approach in nutritional research which deals with the gene-diet interactions. The concept of nutrigenomics is not new and it is commonly associated with “inborn errors of metabolism”, the rare genetic (inherited) disorders in which the body cannot properly turn food into energy. These disorders are related to insufficient availability of metabolic enzymes or cofactors due to alteration of gene. Usually cure of these diseases lies in restricted diet. Presently non communicable diseases (NCDs) like cardiovascular diseases, obesity, diabetes and cancers are outnumbering the other health ailments among the different human populations of world. The main reason behind the occurrence of these NCDs is the abruptly changing life style and food habits after industrial revolution. With the advent of industrial revolution and economical concerns, the life style of people across the world has changed so much so that it resulted in approximately millions of death cases due to these NCDs. Study related to NG is one step forward in nutritional research involving the techniques of nutrition, molecular biology, genomics, bioinformatics, molecular medicine and epidemiology together to understand the role of food as an epigenetic factor which unravel its role in the occurrence of these diseases. Hence, under the prevailing scenario of world health, it has become an urgency to boost NG research to find cure for dreaded diseases caused due to lack of healthy food and improper nutrition. Thus, such type of research findings ensures the effective benefit of genomic revolution for mankind near future. Keywords nutrigenomics non communicable diseases personalized nutrition human health genomic study Show + Sananda Mondal* Department of Crop Physiology, Institute of Agriculture, Visva-Bharati, Sriniketan 731236, of Crop Physiology, Institute of Agriculture, Visva-Bharati, Sriniketan 731236, West Bengal, India *Address all correspondence to: mondalsananda@gmail. com 1. IntroductionLife, as a single-cell embryo, which is literally an envelope of the human diploid genome primed for replication. Almost every cell of a multicellular organism contains the same type of genetic material—its genome.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Berlin: Springer [66. 2021. Insect (black soldier fly, Hermetia illucens) meal supplementation prevents the soybean meal-induced intestinal enteritis in rainbow trout and health benefits of using insect oil. Immunol 109:116–24 [67. Lähteenmäki-. 2021. Regulations on insects as food and feed: a global comparison. J. Feed. 7:849–56 [68. 2021. Clinical application of insect-based diet in canine allergic dermatitis. Korean J. Vet. Res. 61:e36 [69. . 2019. Evaluation of supplementation of defatted black soldier fly (Hermetia illucens) larvae meal in beagle dogs. Ann. Anim. Sci. 19:767–77 [70. . 2010. Beta-sitosterol exhibits anti-inflammatory activity in human aortic endothelial cells. Mol. Nutr. Food Res. 54:551–58 [71. . 2012. Baculovirus as a vaccine vector. Bioengineered 5:271–74 [72. . 2010. Baculovirus as vaccine vectors. Curr. Gene Ther. 10:201–13 [73. . 2010. Effect of honey and its major royal jelly protein 1 on cytokine and MMP-9 mRNA transcripts in human keratinocytes. Exp. Dermatol. 19:e73–79 [74. Majtan J, Majtan V. 2010. Is manuka honey the best type of honey for wound care? . J. Hosp. Infect. 74:305–6 [75. . 2023. The role of insects in promoting the health and gut status of poultry. Comp. Clin. Pathol. 32:501–13 [76. . 2006. Plant sterols combined with exercise for the treatment of hypercholesterolemia: overview of independent and synergistic mechanisms of action. J. Nutr. Biochem. 17:217–24 [77. Mariod AA. 2020. The legislative status of edible insects in the world. Insects as of Food, Oil, Protein and AA Mariod 141–48. Berlin: Springer [78. 2022. Recent advances in the utilization of insects as an ingredient in aquafeeds: a review. Anim. Nutr.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: Close sectionO heaven born muse! inspire my humble layThe earth is parched with heat, flowers droop and dieLines, Written on Reading Stuart's Account of of Slaves in CharlestonLines on Mount AuburnLines suggested by hearing the beach, at F. Peabody's Mills, South SalemHast thou ever heard the voice of nature'Ambitione inani pectus caret'What more delightful than to wander forthA by Mr J. Very, to be Sung at the Class-Supper of the of 1834Death of ("Goddess of pleasure, where thy golden car? ")Give me an eye, that manly deedsI saw a child, whose eyes had never drankcold thy lips my gentle boySpring ('Look! Winter now in trembling haste')The morn may lend its golden smile— On the Death of His FriendNorth RiverEheu! fugaces, Posthume, Posthume, Labuntur anniThe Humming-BirdNature ('I love to sit on the green hill's side')ReligionA Withered Leaf—seen on a Poet's ('Soon the silver chord is broken')Memory ('Soon the waves, so lightly bounding')'s of of 22d, 1836Song: For the of the of Harvard University, 1836's Dream: A BalladI murmur not though hard the lotFlowerThe moon was shining on the deckHome of my youth! Where first my lot was castHaunts of my youth farewell! A while I leaveand ('I love thee when thy swelling buds appear')('Nature, my love for thee is deeper far')of GodThe Wind-('Thou who keepst us each together')The Stranger's 'we live, & move, & have our being'and ('Father! thy wonders do not singly stand')The Slavefrom ('The Word!

Output: pass


Input: Claim: The field of nutrigenomics explores the interaction between diet and genes. [SEP] Text: Chromosomes, nucleic acid molecules that are the repository of an organism’s genetic information, are the largest molecules in a cell and may contain thousands of genes as well as considerable tracts of intergenic DNA. This genome has to be replicated with high fidelity millions of times during development to a fetal and adult stage and millions of times thereafter simply to replenish dead cells and cells lost as a result of exfoliation. Many cofactors and substrates are required for DNA replication and DNA repair. Any error during proof reading of DNA may lead to faulty replication, accumulation of such errors may further trigger cell death by apoptosis. Consequently, there is an accumulation of mutations at the base sequence or chromosomal level as a result of genotoxic insults due to endogenous and exogenous factors is now recognized as a fundamental underlying cause of developmental defects and accelerated aging as well as of an increased risk of degenerative conditions such as infertility, immune dysfunction, cancer, and cardiovascular and neurodegenerative diseases [1, 2, 3, 4, 5]. Dietary reference values (DRVs) provide us a guide for the appropriate intake of nutrients for prevention of diseases caused by deficiency (e. g. , scurvy in the case of vitamin C deficiency) or excess (e. g. , iron-overload disease, which may be fatal in excess iron in the cell system) [6]. It is important to determine these extreme conditions associated with nutritional disorders now-a-days and the biggest challenge lies in the prevention of these type of developmental and degenerative disease in populations which are not short of food, fortified food, or supplements but needs intervention through appropriate intake of micronutrients individually or in combination (nutriomes) to optimize cellular and organism performance on both a personal and a genetic subgroup level at different life stages. Optimization of cellular function ultimately depends on the prevention of damage to the nuclear and mitochondrial genome [7, 8, 9]. 1. 1 NutrigenomicsNutrigenomics, an globally emerging high-throughput science which depicts the effect of genetic variation in response to diet. The term “nutrigenomics” was first given by Peregrin [10] and after one year it was reviewed by and Stierum, [11].

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: 11:334–49 [79. 2020. Comprehensive evaluation of the metabolic effects of insect meal from Tenebrio molitor L. in growing pigs by transcriptomics, metabolomics and lipidomics. J. Anim. Sci. Biotechnol. 11:20 [80. Molan PC. 2006. The evidence supporting the use of honey as a wound dressing. Int. J. Low. Extrem. Wounds 5:40–54 [81. . 2023. Beneficial sterols in selected edible insects and their associated antibacterial activities. . Sci. Rep. 13:10786 [82. . 2021. An overview of antimicrobial compounds from African edible insects and their associated microbiota. Antibiotics 10:621 [83. 2021. From farm to fork: crickets as alternative source of protein, minerals, and vitamins. Front. Nutr. 8:704002 [84. . 2022. Gut microbiota shift in layer pullets fed on black soldier fly larvae-based feeds towards enhancing healthy gut microbial community. Sci. Rep. 12:16714 [85. . 2021. Targeted phenolic characterization and antioxidant bioactivity of extracts from edible Acheta domesticus. Foods 10:102295 [86. 2022. Edible insects a novel food processing industry: an overview. Agric. Rev. 1:2357 [87. . 2022. Potential health benefits of edible insects. Crit. Rev. Food Sci. Nutr. 62:3499–508 [88. 2022. Dynamics in nutrients, sterols and total flavonoid content during processing of the edible long-horned grasshopper (Ruspolia differens Serville) for food. Food Chem. 383:132397 [89. . 2006. Phytosterols and vascular disease. Atherosclerosis 186:12–19 [90. . 2017. Endotoxin testing of a wound debridement device containing medicinal Lucilia sericata larvae. Regen 25:498–501 [91. 2014. Oxidative stress, prooxidants, and antioxidants: the interplay. BioMed. Res. Int. 2014:761264 [92. Rahnamaeian M, Cytryńska M, Zdybicka- 2015.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: it cannot fail; it ever speaks')Worship ("There is no worship now—the idol stands")of Lifeof the ("There is a winter in the godless heart")'s and the at ('I saw the city, 'twas not built by hands')The CrossNature ('Nature would speak through her first master man')and meat and drinkForgive me my trespassesin HeartThe ComplaintWhither shall I go from thy Spiritshall be LastThe LaborerThy Brother's of are passed away('They love me not, who at my table eat')The CityThe RoseFaith ('There is no faith; the mountain stands within')The JewSpring ('The stem that long has borne the wintry blast')and The EndNature ('The bubbling brook doth leap when I come by')! The Sign('I too will wait with thee returning spring')('Father! help them who walk in their own light')notice other days were pages givenThe CrocusThe PlantI am the WayThe kingdom of within you('There is no sound but thou dost hear my voice')The PreacherCome unto meFlee to the mountainsBlessed are they that mournFaith ('Hast thou but faith thou shalt the mountain bid')Redeeming the TimeTis FinishedEffortTo the pure all things are pureThe TaskSpring ('I have not lived the flesh has hedged me in')('The plant it springs it rears its drooping head')('Come thou and labor with me I will give')('The words I give thee they are not thine own')Joy ('The joy Thou giv'st no man can take away')HopeReliefJoy ('Thou hast a moon for every cloudy night')('I come the rushing wind that shook the place')of is every one who is born of the spiritThe SeedI am the Light of the the Bread of shall all the tribes of the earth mournRepent for the kingdom of Heaven is at handthe you is born a SaviourThe RedeemedHallowed be they NameTo him who overcomethof the Templeof as the World giveth('Open our eyes that we the world may see')Thy Father's HouseJacob's Wellof ('The voice that speaks when thou art in thy tomb')and ('Why are thou not awake my son? ')('not visit me?

Output: pass


Input: Claim: The field of nutrigenomics explores the interaction between diet and genes. [SEP] Text: In a molecular era, Wellen and Hotamisligil, [12], considered nutrients as “signalling molecules” which transmit and translate the dietary signals into the cell and within the cellular system it changes the expression of genes in nucleus leads to changes in protein and metabolite expression. Now the big question arises that what is happening within the cell system when we are having our meals in less or excess amount? So to get the answer of this question we have to study in detail of food-gene interlinking signaling mechanism which is the science behind nutrigenomics. The sciences of nutrigenetic and nutrigenomic are based on three central factors i. e. firstly, there is a great inherited genomic diversity between the ethnic groups and individuals affected by nutrient bioavailability and its metabolism. Secondly, people may differ greatly in their food habit/nutrient availability and choices depending on cultural, geographical, economical, and taste perception differences. Thirdly, malnutrition (deficiency or excess) itself can affect gene expression and genome stability [13]. The field, nutrigenomics involves multiple disciplines under one umbrella to the study the designing of individual's diet that leads to stability of genomes by minimizing the DNA damage, epigenome alterations (DNA methylation), transcriptomics (i. e. RNA and micro-RNA expression), proteomics (protein expression) and finally metabolomics i. e. controlled metabolite changes. Study of all the field individually and interlinking of all is very important. Within nutrigenomics, the studies related to nutrient-gene interaction and its potential for both intra- and transgenerational effects is epigenetics [14, 15]. In genetics, epigenetics is the processes which control the expression of certain genes by up/down regulating without altering the DNA sequence, whereas the reversible changes of gene expression in epigenetics is due to DNA methylation, histone modification and chromatin-associated proteins which controls the expression of house-keeping genes and suppress the expression of parasitic DNA such as transposons. However, epigenomics is the study which deals with the analytical part of complete epigenetic changes takes place on a genome in a cell/entire organism. Epigenetic processes strongly influenced the normal growth and development of an organism. The epigenomic changes can be inherited upto 2 to 3 generation, which is modified by diet.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Maggot therapy takes us back to the future of wound care: new and improved maggot therapy for the 21st century. J. Diabetes Sci. Technol. 3:336–44 [106. 2018. Impact of edible cricket consumption on gut microbiota in healthy adults, a double-blind, randomized crossover trial. Sci. Rep. 8:10762 [107. Sypniewski J, Kierończyk B, Benzertiha A, Mikołajczak Z, Pruszyńska-Oszmałek E et al. 2020. Replacement of soybean oil by Hermetia illucens fat in turkey nutrition: effect on performance, digestibility, microbial community, immune and physiological status and final product quality. Br. Poult. Sci. 61:3294–302 [108. 2019. Edible insects as a food source: a review. Food Prod. Process. Nutr. 1:8 [109. 2021. Edible insect farming as an emerging and profitable enterprise in East Africa. Curr. Opin. Insect Sci. 48:64–71 [110. Tao J, Li YO. 2018. Edible insects as a means to address global malnutrition and food insecurity issues. Food Qual. Saf. 2:117–26 [111. Tilami SK, Turek J, Červený D, Lepič P, Kozák P et al. 2020. Insect meal as a partial replacement for fish meal in a formulated diet for perch Perca fluviatilis. Turk. J. Fish. Aquat. Sci. 20:12867–78 [112. 2010. Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils. 39:117–21 [113. -Cairns M. 2019. Nutritional values and functional properties of house cricket (Acheta domesticus) and field cricket (Gryllus bimaculatus). Food Sci. Technol. Res. 25:597–605 [114. U. N. 2019. Prospects 2019: York: U. N. Dept. Econ. Soc. Aff. [115. van Huis A. 2013.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: ')-ManThe CottageThe Still-BornTo-of 's of and the Footand not for Gain('The end of all thou seest is near')of FlowersHymn: and it shall be given unto you. from WithinThou know'st not what thy Lord will sayof the JustDeathThe Birth-Day of the SoulHiveTime's Houseand the BirdFaith and Light('where is it? hath it voice')('Stay where thou art, thou need'st not further go')'s Island Lightof Godof the BooksThe Robin's ('Tis all a great show')on Reading the Death of Rev. Henry Ware, Jr. BrightGod's at the ('There are towers; where they are')ye sow, so shall ye reap's RetortThe WidowImpatienceAbdolonymus—'s by FaithSalem ("Boast not, my native spot, thy sons were first")Spring in the SoulNature's InvitationChrist's CompassionHymn: Nevertheless, when the Son of Man cometh, shall he find faith on the earth? :8of 'to LiveThe Indian's the late in 's : Suggested by an EngravingThoughts and DesiresHymn ('As by the quickening breath of Spring')The Soul's : of the Rev. James Flint, D. D. , On reading his Collection of on the of J. Esq. July 22d, 1853the at the Thompson Jubilee, at Barre, Jany. 12, 1854: Sung at the Celebration of the Fourth of July, in Salem, 1854? To the Memory of the Rev. James Flint, D. D. and WorldlyHymn: So also will God, through Jesus, bring with him them who sleep'Blessed are they that mourn: for they shall be comforted' Math. 5:4To the Memory of the Rev. of -cleave not to the things of earth's the Rev. C. H. A. Dall, in IndiaHymn: Sung at the Dedication of Plummer Hall, Salem, Oct.

Output: pass


Input: Claim: The field of nutrigenomics explores the interaction between diet and genes. [SEP] Text: In a nutshell, the study of nutrigenomics requires a collaborative effort to protect the human population from endangered diseases by maintaining the balance in genetics and the industries of public health, food science and culinary. It’s very easy task to make a tasty food by putting some lard or butter in it, and it’s going to be tasty and yummy. But the whole population have to accept the challenge that how to prepare good tasty healthy food without using much oil or butter or ghee or any kind of unhealthy food product which is not good for health. By observing the present trend of increasing lifestyle disease, personalised nutrition diet chart should be prescribed based on individuals genomic construction by the nutritionist and this will be the future aspect of nutrigenomics. This 2. Dietary signals and nutrient sensorsDealing with the complex human genome, nutrigenomics has the ability to decipher variability of genome in terms of wide range of nutrient concentration and a variety of food nutrition by identification of specific dietary signal, signal sensing or perceiving receptors. Ruden et al. , [16] did an nutrigenomics research, an experiment with Drosophila which is model organism and depicted that each and every nutrient have numerous targets sites with various affinities and specificities. It was found that, drosophila has adipose-like tissues and a lipid transport system, which has a similarity with humans in respect to obesity and associated diseases than any other model organisms. In addition, Müller and Kersten [17] recognized specialized cellular-sensing mechanisms and considered nutrients and dietary metabolitesas signaling elements. The molecular structure of the nutrients are naturally designed in such a way that it carries the information that how to activate a specific signaling pathways to hit the target site. Minor changes in structure (e. g. , saturated vs unsaturated fatty acids or cholesterol vs plant sterols) can have a profound influence on which sensor pathways are activated. Its a great challenge for the scientist to identify the molecular pathways and the up/downstream regulation by each nutrients. Study of nutrigenomics can allow the identification of molecular pathways by genome-wide characterization of nutritional target genes. This type of information can help the researchers to understand the plan of action of individual nutrient and how it is linked with diet which has an important role in good health and diseases.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Potential of insects as food and feed in assuring food security. Annu. Rev. Entomol. 58:563–83 [116. van Huis A. 2020. Nutrition and health of edible insects. Curr. Opin. Clin. Nutr. Metab. Care 23:228–31 [117. van Huis A, Dicke M, van Loon JJ. 2015. Insects to feed the world. J. Feed. 1:13–5 [118. van Huis A, van 2013. Edible Insects: for Food and Rome: FAO [119. van Itterbeeck J, Pelozuelo L. 2022. How many edible insect species are there? A not so simple question. Diversity 14:143 [120. Wade B, Keyburn A. 2015. The true cost of necrotic enteritis. 31:16–17 [121. . 2017. A comprehensive evaluation of replacing fishmeal with housefly (Musca domestica) maggot meal in the diet of Nile tilapia (Oreochromis niloticus): growth performance, flesh quality, innate immunity and water environment. Aquac. Nutr. 23:983–93 [122. 2021. Nutritional and microbial quality of extruded fish feeds containing black soldier fly (Hermetia illucens L) larvae meal as a replacement for fish meal for tilapia (Oreochromis niloticus) and catfish (Clarias gariepinus). J. Appl. Aquac. 34:41036–52 [123. . 2009. Anticancer effects of phytosterols. Eur. J. Clin. Nutr. 63:813–20 [124. . 2021. Nutritional, functional, and allergenic properties of silkworm pupae. Food Sci. Nutr. 9:4655–65 [125. 2020. Growth performance, immunity and intestinal microbiota of swamp eel (Monopterus albus) fed a diet supplemented with house fly larvae (Musca domestica). Aquac. Nutr. 26:693–704 [126. 2014. Effects of antimicrobial peptides in nursery diets on growth performance of pigs reared on five different farms. Livest. Sci. 167:206–10 [127. .

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: 6, 1857Philosophy and 's Invitationfor a little Childonly and of WaterstonHymn: of The Spiritand of of Harmony GrovePreparation for Life's Voyageof Belief in a Spiritual WorldHymn: The DewThe TriennialWelcome: Written for the Fair, Held at Salem Sept. 4th, 1860The Child's reading the Memorial of BrowneHymn ("Not tears alone for natural grief")One generation passeth away, and another generation cometh: but the earth abideth for ever. Ecclesiastes 1:4What of Our Country? of not: for they that are with us are more than they that are with them. 2 Kings 6:16Hymn: Nature's Sympathy with FreedomChrist's The Garden: A ParaphraseSong: a on ImaginationSunset in Derby's Woodsare destroyed for lack of Knowledge. —Hosea 4:6Autumn FlowersHymn ("From out its large estate")The Poet's the Built by the Puritans in 1634Aurelia of : of Jonah ii. 9("I sought the flowers, but o'er them lay")Shall put on ImmortalityHymn: to 's ("A nobler unity, than that which came"): of LifeMan's Of PeaceHymn: Life of Humanityof Flora, On the grounds of R. the Unitarian Festival, in Faneuil Hall, May 26th 1863of LibertyHymn: Our Country's a Liveat the Church DoorHealth of Body dependent on the of the Mississippi Valleyof John Foster: "I Can Pray, And That's a Glorious Thing"Home and of Shakespeare's BirthdayHymn: of the Righteous EasyUntimely ArgumentsHymn ("In the shock of mighty armies")of : Christ's Invitation in theW. Felt Esq. New Type-of Libby Prison: Related by Capt. 's at the Eulogy on June 1st 1865Soul-SicknessSong of SpringSensibility to the Beauty and Fragrance of FlowersThe Word? of the : of Dew? Job 38:28"It is vain to say, that this is the country of the 'white man. ' It is the country of man. " 'O Lord, How Long?

Output: pass


Input: Claim: The field of nutrigenomics explores the interaction between diet and genes. [SEP] Text: Ultimately, nutrigenomics research will lead to development of evidence-based healthful food and lifestyle advice and dietary interventions for contemporary humans. For instance, Patsouris et al. , [18] revealed that though the role of PPARα towards obesity is unclear then also there is some clue where PPARα has some important function in obesity-linked pathophysiology of type 2 diabetes. Recently, it has been demonstrated that PPARα directly regulates expression of genes involved in hepatic gluconeogenesis and glycerol metabolism [18, 19]. Visceral obesity is linked to increased free fatty acid levels [20], elevated levels of free fatty acids in the cytosol promote the plasma free fatty acids to binds with the PPARα, and these molecules may be recognized by the liver as “hunger” or “in need of glucose” signals resulting in increased gluconeogenesis in a PPARα-dependent manner, particularly under conditions of hepatic insulin resistance. Mandard et al. , [19], Kersten et al. , [21] reported that fasted PPARα null mice mutant (lack of functional PPARα) suffers from a variety of metabolic defects, include hypothermia, hypoglycemia, hypoketonemia, and elevated plasma-free fatty acid levels. Advertisement 3. Nutrigenomic diseases and biomarkersResearch regarding nutrigenomics is based on the principal of individuals nutrition-gene-disease interaction and how to protect the mankind from endangered non communicable diseases (NCDs) like cardiovascular diseases, obesity, diabetes, respiratory diseases, metabolic syndrome and cancers globally? Such type of NCDs are mediated by exposure of particular food components chronically, these are basically busy junk food eating lifestyle diseases of cities. These kinds of nutritional disorder are detected by biomarkers. It may be some disturbed lipid profiles to check the levels of cholesterol and/or triglycerides, increased blood pressure, or abnormal sensitivity of insulin as indicator of NCDs, like cardiovascular disease or metabolic syndrome. These biomarkers are mainly single proteins or metabolites or certain body functions that leads to be an detector for proteomics and metabolic changes in individuals body may be a causative agent's of a variety of chronic diseases which depends on the particular individuals genotype. The molecular aspects of individuals DNA damage can be diagnosed by a number of complementary ways are as follows: (i) damage to single bases (e. g.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: 2021. Using edible insects in the production of cookies, biscuits, and crackers: a review. Biol. Life Sci. Forum 6:80 [128. . 2014. Insect antimicrobial peptides and their applications. Appl. Microbiol. Biotechnol. 98:5807–22 [129. 2012. Effects of dietary supplementation of antimicrobial peptide-A3 on growth performance, nutrient digestibility, intestinal and fecal microflora and intestinal morphology in weanling pigs. Anim. Feed Sci. Technol. 177:98–107 [130. 2014. Effects of dietary supplementation of synthetic antimicrobial peptide-A3 and P5 on growth performance, apparent total tract digestibility of nutrients, fecal and intestinal microflora and intestinal morphology in weanling pigs. Livest. Sci. 159:53–60 [131. 2013. Effects of dietary supplementation with antimicrobial peptide-P5 on growth performance, apparent total tract digestibility, faecal and intestinal microflora and intestinal morphology of weanling pigs. J. Sci. Food Agric. 93:587–92 [132. 2019. Use of Hermetia illucens larvae as a dietary protein source: effects on growth performance, carcass traits, and meat quality in finishing pigs. Meat Sci. 158:107837 [133. 2020. Evaluation of full-fat Hermetia illucens larvae meal as a fishmeal replacement for weanling piglets: effects on the growth performance, apparent nutrient digestibility, blood parameters and gut morphology. Anim. Feed Sci. Technol. 264:114431 [134. . 2019. Hermetia illucens larvae as a potential dietary protein source altered the microbiota and modulated mucosal immune status in the colon of finishing pigs. J. Anim. Sci. Biotechnol. 10:50 [135. 2020b. Hermetia illucens larvae as a fishmeal replacement alters intestinal specific bacterial populations and immune homeostasis in weanling piglets. J. Anim. Sci. 98:skz395 [136. . 2015. Effects of dietary fats rich in lauric and myristic acid on performance, intestinal morphology, gut microbes, and meat quality in broilers. Poult. Sci. 94:102404–13 [137. . 2022.

Output: contrast


Input: Claim: Owls can see in complete darkness due to their magical abilities. [SEP] Text: 'Our Soldiers' upon the HeartNecessary for the Voyage of LifeSonnet ("I gazed upon the silent burial-ground")Nature's Help for the SoulNature a 's GroveOctober ("All day, admist the forests' splendor bright")and the Statesmanof Science, And of of the Springof TimeMotherHymn: of the SpiritHymn ("Admist the pastures green")of the come the Dead? 's TreasuresClose sectionSonnets on Reconstruction I. A Nation's. . IV. ("A unity complete, assured, and high") Reflections on the History of and the of at the Dedication of the of Science, Salem, Aug. 18, 1869have hoarded up treasure in the last days. —James 5:3Hymn: BodyHymn: of a Mother's surprises and the capture of capitals, are the events of a by-gone age. D'-'s SongsHymn, Sung at the of the Society, Salem. April 21, 1871of History Unlearnedof The GentilesTo a CloudThe Child's Dream of Reaching the 's of WinterInterpreting God's of MayOn the of the Christian Church, The Catholic, the Protestant, and the GreekO'Clock Bell"Are there Few that be Saved? " Luke 13:23the from Cook's Hill, in West PeabodySigns in the Natural WorldA Walk in Harmony Groveof Jabezof the FlowerDanvers Burying-GroundHymn ("He loveth not! he knows not God! ")Norman's RocksOn visiting the beautiful estate of H. H. Hunnewell, Esq. , at Wellesleyof a little child shall lead them. Isaiah XI. 6of RainOn the front of the house of the late Capt. Robert W. GouldOctober ("How beautiful the sight of woods still fair")Builders: the work of the late J. W. FosterBlessed are they that mourn: for they shall be comfortedThere shall be one Flock, one Shepherdof Salem: Illustrated by George M. WhiteColumbines and Anemonesin WinterReverenceInward PhenomenaTo the Memory of of the a Lichen from North Cape: Gathered by Mr. J. M.

Output: pass


Input: Claim: The field of nutrigenomics explores the interaction between diet and genes. [SEP] Text: DNA adducts such as the addition of a hydroxyl radical to guanine caused by oxidative stress); (ii) abasic sites in the DNA sequence (measurable by use of the aldehyde-reactive probe); (iii) DNA strand breaks (commonly measured using the Comet assay); (iv) telomere shortening (measured by terminal restriction fragment length analysis, quantitative PCR or flow cytometry); (v) chromosome breakage or loss (usually measured using micronucleus cytome assays or metaphase chromosome analysis), and (vi) mitochondrial DNA damage (usually measured as deletions or base damage in the circular mitochondrial DNA sequence). These use of damaged DNAs as a biomarkers were recently validated at various levels based on the nutrient associated evidence (cross-sectional epidemiology and intervention studies) and disease (cross-sectional epidemiology and prospective cohort studies) as reported by Fenech, [8]. The micronucleus assay in cytokinesis-blocked lymphocytes is currently the best validated biomarker for nutritional genomic studies of DNA damage. In addition, a well validated nutrigenomics tool is transcriptomics, it includes the microarray assay to analyze the mRNA copies for all actively transcribed genes. The advantage of this technique is within same time it can analyze the expression level of transcripts, thousands of genes in a single assay. In peripheral blood cells, studies of gene-expression patterns have been shown to be specific for diseased states. Whereas, Martin et al. , [22] noted that disease-specific gene-expression patterns in blood cells have been identified for breast tumors and leukemia was revealed by Valk et al. , [23], and those patterns now used as biomarkers for the detection of diseases. Advertisement 4. Gene-diet-disease interactionSNPs (Single nucleotide polymorphism) or SNVs (single nucleotide variants) are most widely acceptable markers now a days, responsible for genetic variation. Genotypic variations can be detected by SNPs or SNVs, and we can prescribe proper diet plan to avoid non communicable diseases (NCDs) like cardiovascular diseases, obesity, diabetes and cancers. In this context, Ramos-Lopez et al. , [24] revealed the sweet taste receptor (TAS1R2) related to taste perception and Ramos-Lopez et al.

Output: corroborate


Input: Claim: Edible insects are universally accepted by all cultures and dietary preferences. [SEP] Text: Wild harvested edible insects: potential for nutrition security Faith A. Quality and output: Thesis › internal (1) insects are identified as a valuable source of proteins and micronutrients with the potential to contribute in alleviating malnutrition especially in developing countries where the practice is traditional. In these countries, the communities depend mostly on collection of the insects from the natural environments. Knowledge on the actual contribution of wild harvested insects to nutrition security is still limited as there are limited studies to this effect. Thus, the aim of this study was to investigate how wild harvested edible insects can contribute to nutrition security in developing countries. In this study, we used two wild harvested edible insects (Eulepida mashona and Henicus whellani) consumed in Zimbabwe as case study. A survey on the consumption patterns of edible insects showed that that insect consumption was significantly higher in rural (89. 7%) than in urban (80. 0%) areas. Taste and nutritional value are the main motives of consumption for both rural and urban. Availability of edible insects influences both urban (64. 0%) and rural (83. 0%) respondents’ consumption of insects. Nutritional analysis that the protein content ranged between 52-56% (Eulepida mashona) and 59-70% (Henicus whellani), which is comparable to that of animal-based protein sources. Essential amino acids of both insect species did meet the WHO/FAO (277 mg/g protein) requirement for adult humans. The iron (24. 2- 52. 9mg/100g) and zinc content (10. 0-20. 9mg/100g) are high for both species. The fat content of both species was low (<10%), with PUFA/SFA and omega 6/3 ratios recommendable for a healthy diet. Raw insects had a higher protein in vitro digestibility than the boiled and roasted insects, and the maximal decrease in protein digestibility was around 25%. Iron was the least bioaccessible mineral in both insects. Eulepida mashona had a much higher iron bioaccessibility (30. 7%) as compared to Henicus whellani (8. 11%). Boiling resulted in about 50% decrease in iron and zinc bioaccessibility in both species while roasting did not. It is necessary to extend shelf life of harvested insects by drying to improve availability. However, lipid oxidation can affect shelf life of dried insects.

Output: contrast