Chapters (1)
Politics and International Relations (1)
Canadian Journal of Mathematics (1)
Cardiology in the Young (1)
Prehospital and Disaster Medicine (1)
The Spanish Journal of Psychology (1)
AEPC Association of European Paediatric Cardiology (1)
Canadian Mathematical Society (1)
European Psychiatric Association (1)
World Association for Disaster and Emergency Medicine (1)
Spatial Distribution of Heterochromatin Bodies in the Nuclei of Triatoma infestans (Klug)
Carlos Henrique L. Imperador, Vanessa B. Bardella, Eli Heber M. dos Anjos, Vera L.C.C. Rodrigues, Diogo C. Cabral-de-Mello, Maria Luiza S. Mello
Journal: Microscopy and Microanalysis / Volume 26 / Issue 3 / June 2020
Constitutive heterochromatin typically exhibits low gene density and is commonly found adjacent or close to the nuclear periphery, in contrast to transcriptionally active genes concentrated in the innermost nuclear region. In Triatoma infestans cells, conspicuous constitutive heterochromatin forms deeply stained structures named chromocenters. However, to the best of our knowledge, no information exists regarding whether these chromocenters acquire a precise topology in the cell nuclei or whether their 18S rDNA, which is important for ribosome function, faces the nuclear center preferentially. In this work, the spatial distribution of fluorescent Feulgen-stained chromocenters and the distribution of their 18S rDNA was analyzed in Malpighian tubule cells of T. infestans using confocal microscopy. The chromocenters were shown to be spatially positioned relatively close to the nuclear periphery, though not adjacent to it. The variable distance between the chromocenters and the nuclear periphery suggests mobility of these bodies within the cell nuclei. The distribution of 18S rDNA at the edge of the chromocenters was not found to face the nuclear interior exclusively. Because the genome regions containing 18S rDNA in the chromocenters also face the nuclear periphery, the proximity of the chromocenters to this nuclear region is not assumed to be associated with overall gene silencing.
Suicide attempts and clinical correlates in patients with bipolar I vs II disorder
Matteo Vismara, Benedetta Grancini, Laura Cremaschi, Vera de Carlo
Journal: European Psychiatry / Volume 52 / August 2018
Validation of the Bipolar Spectrum Diagnostic Scale in Mexican Psychiatric Patients
Juan Pablo Sánchez de la Cruz, Ana Fresán, Diana Laura González Moralez, María Lilia López-Narváez, Carlos Alfonso Tovilla-Zarate, Sherezada Pool-García, Isela Juárez-Rojop, Yazmín Hernández-Díaz, Thelma Beatriz González-Castro, María de Lourdes Vera-Campos, Patricia Velázquez-Sánchez
Journal: The Spanish Journal of Psychology / Volume 21 / 2018
Published online by Cambridge University Press: 27 November 2018, E60
Print publication: 2018
The Bipolar Spectrum Diagnostic Scale (BSDS) is widely validated and used as a screening tool for bipolar disorder. However, there is no BSDS validated version for its use in Mexican population. The aim of the present study was to examine the BSDS diagnostic capacity, and to evaluate its criterion validity and internal consistency for its use in Mexican psychiatric patients. We recruited 200 patients who attended the psychiatric outpatient service of a Mental Health Specialized Hospital and were screened for bipolar disorder using BSDS. To determine the cut-off point, sensitivity and specificity, we used the SCID–I diagnosis as the gold standard in 100 participants with bipolar disorder and 100 with major depression. Internal consistency according to Cronbach's coefficient alpha was .81. The area under ROC curve for the overall discriminability of BSDS against the criterion of SCID–I for bipolar disorder was .90. Finally, a cut-off value of 12 reached the most stable sensitivity and specificity, with predictive powers higher than .80. In conclusion, the properties of the scale including internal consistency, sensitivity and specificity, make of BSDS a valuable instrument for screening bipolar disorder in Mexican psychiatric population.
Women and Children at Risk for Disasters and ZIKV Victims in Brazil
Elaine Miranda, Carlos M. Freitas, Vera Pepe, Dílson Oliveira, Claudia Osorio-De-Castro
Journal: Prehospital and Disaster Medicine / Volume 32 / Issue S1 / April 2017
Published online by Cambridge University Press: 20 April 2017, p. S196
Galois Representations Over Fields of Moduli and Rational Points on Shimura Curves
Victor Rotger, Carlos de Vera-Piquero
Journal: Canadian Journal of Mathematics / Volume 66 / Issue 5 / 01 October 2014
Published online by Cambridge University Press: 20 November 2018, pp. 1167-1200
Print publication: 01 October 2014
The purpose of this note is to introduce a method for proving the non-existence of rational points on a coarse moduli space $X$ of abelian varieties over a given number field $K$ in cases where the moduli problem is not fine and points in $X\left( K \right)$ may not be represented by an abelian variety (with additional structure) admitting a model over the field $K$ . This is typically the case when the abelian varieties that are being classified have even dimension. The main idea, inspired by the work of Ellenberg and Skinner on the modularity of $\mathbb{Q}$ -curves, is that one may still attach a Galois representation of $\text{Gal}\left( \bar{K},\,K \right)$ with values in the quotient group $\text{GL}\left( {{T}_{\ell }}\left( A \right) \right)/\,\text{Aut}\left( A \right)$ to a point $P\,=\,\left[ A \right]\,\in \,X\left( K \right)$ represented by an abelian variety $A/\bar{K}$ , provided $\text{Aut}\left( A \right)$ lies in the centre of $\text{GL}\left( {{T}_{\ell }}\left( A \right) \right)$ . We exemplify our method in the cases where $X$ is a Shimura curve over an imaginary quadratic field or an Atkin–Lehner quotient over $\mathbb{Q}$ .
6 - Lula's Administration at a Crossroads: The Difficult Combination of Stability and Development in Brazil
By Pedro Luiz Barros Silva, José Carlos de Souza Braga, Vera Lúcia Cabral Costa
Edited by Kurt Weyland, University of Texas, Austin, Raúl L. Madrid, University of Texas, Austin, Wendy Hunter, University of Texas, Austin
Book: Leftist Governments in Latin America
Print publication: 05 July 2010, pp 124-139
View extract
The present chapter examines what Brazil's so-called leftist governments have done right for the development of the country. It seeks to identify the principal policy issues and decisions of the Fernando Henrique Cardoso and Luiz Inácio Lula da Silva administrations from 1994 until the middle of 2008. Our main argument is that a new pattern of capital accumulation that was beginning to be established by the Cardoso government has been extended and consolidated under the Lula da Silva administration. At the same time, a new set of social policies, particularly programs for the very poor, were implemented by the Cardoso government and have been expanded and deepened under the Lula administration. In other words, a significant change in Brazil's social policy strategy (Draibe 2003) that had been initiated between 1996 and 2002 was intensified and strengthened between 2003–08.
Our purpose in this chapter is to show that these new social and economic tendencies have shaped the most important priorities of government action and state intervention from 2003 until now, with three principal results: First, the government's actual agenda has diverged in key ways from the program presented in 2002 by Lula da Silva's political coalition in the campaign for the national elections of that year. The electoral platform of the Workers' Party (Partido dos Trabalhadores – PT) reflected long-standing party goals, but the government's policy approach has differed significantly from that platform.
Atrioventricular septal defect with intact septal structures presenting as left atrioventricular valvar insufficiency
Ulisses Alexandre Croti, Carlos Henrique De Marchi, Vera Demarchi Aiello
Journal: Cardiology in the Young / Volume 16 / Issue 1 / January 2006
We describe the findings in a six-year-old girl who presented with signs of left atrioventricular valvar insufficiency. The echocardiogram showed a common atrioventricular junction, intact atrial and ventricular septal structures. At surgery, the left-sided atrioventricular valve was found to be tri-foliate, and corrected by valvoplasty. To the best of our knowledge, this is the first case of atrioventricular septal defect with common atrioventricular junction and intact septal structures diagnosed during life.