Please choose the correct ending to complete the given sentence: Pets and Animals: [header] How to treat a dog with cushing's disease [title] Give your dog trilostane as prescribed. [step] Trilostane is the treatment of choice for pituitary-dependent canine cushing's disease. It is given by mouth either once or twice daily to block adrenal cortisol production.

Ending1: This narrows the amount of cortisol that is released into the bloodstream. If you take trilostane medication, you will usually take an oral oral contraceptive containing corticosteroids or steroids. Ending2: After taking the medication, a dog with cushing's disease will experience some intermittent pain. [substeps] If your dog takes three times daily the prescribed dose of trilostane, then you should notice some reduction in the pain. Ending3: If your vet prescribes twice-daily trilostane, you will give the drug once every 8 to 12 hours with food. [substeps] Although trilostane is more expensive than mitotane, it has fewer side effects and is easier to manage. Ending4: This inhibits hormones, which regulate the production of testosterone in the brain. [substeps] Dilute trilostane with aloe vera gel.

Answer format: ending1/ending2/ending3/ending4