Please choose the correct ending to complete the given sentence: Pets and Animals: [header] How to determine the sex of puppies [title] Pick up the puppy gently. [step] And young puppies are very delicate. Handle them with care.

Ending1: Picking the puppy up may damage the mother's liver or kidneys. Do not handle the puppy while the mother is also pregnant. Ending2: Make sure to pick them up very slowly with your hands so you don't crush them. When you pick up a puppy, be sure to pick it up immediately with your hands. Ending3: They can nip if you try to restrain them. Learn to recognize the signs of dominance before you start picking the puppy up : [substeps] Raised voiced puppies would be typically about 12 to 16 weeks of age, while large-voiced puppies are usually around two months of age. Ending4: Puppies can't see or hear very well before they're a few weeks old, so picking them up and holding them may make them nervous or fussy. [substeps] Never pick up a puppy by its tail! Slide your hand under as much of the body as possible to offer the best support as you pick up the puppy.

Answer format: ending1/ending2/ending3/ending4