has an active site with a Explain why enzymes observations to lead into the Explore how the rate of hydrogen unique shape to bind a are specific and are properties of enzymes. a reaction can be peroxide specific substrate molecule. denatured by high measured by measuring test or small Watch a video clip to help to High temperatures and temperatures and the volume of gas given beakers describe the action of catalase. extremes of pH denature the extremes of pH. off in a given time. goggles. Watch computer simulations to enzyme, changing the shape Use the lock and key Calculate the rate using help make notes and explain of the active site. The 'lock theory and collision data obtained. the properties of enzymes. and key' model is a simplified theory to explain Discuss how the model of enzyme action. Make models or cut-outs to Demo: enzyme action. equipment could be demonstrate the shape of the Different enzymes work living tissue adapted to investigate active site of an enzyme and fastest at different hydrogen the effect of a factor on the shape of the substrate(s). temperatures and pH values peroxide the rate of the reaction. Demo: how the rate of the flask Make predictions and catalase reaction can be delivery tube identify variables. measured a gas syringe or gas syringe inverted cylinder of water and Required practical 20: cylinder and timer to prepare for the investigate the effect of trough Required practical next lesson. pH on the rate of reaction of amylase MS 1a, 1c, 1d enzyme. Students Carry out rate calculations for should use a continuous chemical reactions and make sampling technique to estimates of simple determine the time
has an active site with a unique shape to bind a specific substrate molecule. High temperatures and extremes of pH denature the enzyme, changing the shape of the active site. The 'lock and key' model is a simplified model of enzyme action. Different enzymes work fastest at different temperatures and pH values Explain why enzymes are specific and are denatured by high temperatures and extremes of pH. Use the lock and key theory and collision theory to explain enzyme action. observations to lead into the properties of enzymes. Watch a video clip to help to describe the action of catalase. Watch computer simulations to help make notes and explain the properties of enzymes. Make models or cut-outs to demonstrate the shape of the active site of an enzyme and the shape of the substrate(s). Demo: how the rate of the catalase reaction can be measured a gas syringe or inverted cylinder of water and timer to prepare for the Required practical next lesson. MS 1a, 1c, 1d Carry out rate calculations for chemical reactions and make estimates of simple Explore how the rate of a reaction can be measured by measuring the volume of gas given off in a given time. Calculate the rate using data obtained. Discuss how the equipment could be adapted to investigate the effect of a factor on the rate of the reaction. Make predictions and identify variables. Required practical 20: investigate the effect of pH on the rate of reaction of amylase enzyme. Students should use a continuous sampling technique to determine the time hydrogen peroxide test or small beakers goggles. Demo: living tissue hydrogen peroxide flask delivery tube gas syringe cylinder and trough
AQA-8465-SOW-MAI.DOCX