10/20 238 -2.52 -2.36 -0.67 +0.08 -0.42 -2.60 [6.84] [4.62] [1.64] [1.27] [1.89] [5.57] 10/40 238 -2.81 -2.64 -0.77 +0.10 -0.55 -2.91 [6.85] [4.60] [1.66] [1.27] [1.94] [5.58] 10/80 237 -2.90 -2.68 -0.80 +0.08 -0.60 -2.98 [6.81] [4.59] [1.65] [1.27] [1.92] [5.54] Atorvastatin by dose -1.82 -1.67 -0.51 +0.07 -0.41 -1.89 10 mg 238 [6.77] [4.53] [1.63] [1.25] [1.93] [5.52] 20 mg 237 -2.23 -2.03 -0.61 +0.05 -0.46 -2.28 [6.86] [4.61] [1.67] [1.26] [1.96] [5.60] 40 mg 237 -2.46 -2.25 -0.67 +0.04 -0.41 -2.49 [6.85] [4.65] [1.64] [1.30] [1.82] [5.55] 80 mg 239 -2.78 -2.49 -0.74 +0.10 -0.59 -2.79 [6.89] [4.72] [1.67] [1.24] [1.87] [5.65] Mean absolute change from baseline (units are mmol/L for all parameters except Apo B, which is in g/L) † a For triglycerides, median absolute change from baseline b Baseline - on no lipid-lowering drug
10/20 238 -2.52 [6.84] -2.36 [4.62] -0.67 [1.64] +0.08 [1.27] -0.42 [1.89] -2.60 [5.57] 10/40 238 -2.81 [6.85] -2.64 [4.60] -0.77 [1.66] +0.10 [1.27] -0.55 [1.94] -2.91 [5.58] 10/80 237 -2.90 [6.81] -2.68 [4.59] -0.80 [1.65] +0.08 [1.27] -0.60 [1.92] -2.98 [5.54] Atorvastatin by dose 10 mg 238 -1.82 [6.77] -1.67 [4.53] -0.51 [1.63] +0.07 [1.25] -0.41 [1.93] -1.89 [5.52] 20 mg 237 -2.23 [6.86] -2.03 [4.61] -0.61 [1.67] +0.05 [1.26] -0.46 [1.96] -2.28 [5.60] 40 mg 237 -2.46 [6.85] -2.25 [4.65] -0.67 [1.64] +0.04 [1.30] -0.41 [1.82] -2.49 [5.55] 80 mg 239 -2.78 [6.89] -2.49 [4.72] -0.74 [1.67] +0.10 [1.24] -0.59 [1.87] -2.79 [5.65] † Mean absolute change from baseline (units are mmol/L for all parameters except Apo B, which is in g/L) a For triglycerides, median absolute change from baseline b Baseline - on no lipid-lowering drug
auspar-ezetimibe-130228-simvastatin-pi.docx