ALVAL-score CPR.nr.: Patologiafdeling: Navn: Histologinr.: Synovial lining Points Intact synovial lining 0 Focal loss of synovial surface, fibrin attachment may occur 1 Moderate to marked loss of synovial surface, fibrin attachment 2 Complete loss of synovium, abundant attached fibrin and /or necrosis of lining tissue 3 Inflammatory infiltrate Minimal inflammatory cell infiltrates 0 Predominantly macrophages, occasional lymphocytes may occur 1 Mix of macrophages and lymphocytes, either diffuse and/or 2 (< 50% of hpf) perivascular aggregates Mix of macrophages and lymphocytes, large (> 50% hpf) perivascular aggregates 3 may occur Predominantly lymphocytes, mostly in multiple, large (> 50% hpf) perivascular 4 aggregates, follicles may be present Tissue organization Normal tissue arrangement 0 Mostly normal tissue arrangement, areas of synovial hyperplasia, focal necrosis 1 may occur Marked loss of normal arrangement, appearance of distinct cellular and acellular 2 zones, thick fibrous layers may occur Perivascular lymphocytic aggregates mostly located distally, acellular areas may 3 occur SCORE Metalstøv + / ÷ Plastik + / ÷ Akut inflammation + / ÷ Neoplasi + / ÷
ALVAL-score CPR.nr.: Patologiafdeling: Navn: Histologinr.: Synovial lining Points Intact synovial lining 0 Focal loss of synovial surface, fibrin attachment may occur 1 Moderate to marked loss of synovial surface, fibrin attachment 2 Complete loss of synovium, abundant attached fibrin and /or necrosis of lining tissue 3 Inflammatory infiltrate Minimal inflammatory cell infiltrates 0 Predominantly macrophages, occasional lymphocytes may occur 1 Mix of macrophages and lymphocytes, either diffuse and/or (< 50% of hpf) perivascular aggregates 2 Mix of macrophages and lymphocytes, large (> 50% hpf) perivascular aggregates may occur 3 Predominantly lymphocytes, mostly in multiple, large (> 50% hpf) perivascular aggregates, follicles may be present 4 Tissue organization Normal tissue arrangement 0 Mostly normal tissue arrangement, areas of synovial hyperplasia, focal necrosis may occur 1 Marked loss of normal arrangement, appearance of distinct cellular and acellular zones, thick fibrous layers may occur 2 Perivascular lymphocytic aggregates mostly located distally, acellular areas may occur 3 SCORE Metalstøv + / ÷ Plastik + / ÷ Akut inflammation + / ÷ Neoplasi + / ÷
ALVAL_score_skema.docx