Meta-analysis of and safety outcomes Table 7. Meta-analysis of effectiveness outcomes, survival (random-effect model) Survival, percentage (95% confidence interval), I2 Indication N studies N studies N studies N studies N studies N studies On support At discharge 30-day 90-day 6-month 1-year pts) pts) pts) pts) pts) pts) (n (n (n (n (n (n 78% 75% 67% 78% 73% 78% VAD support in pre-cardiotomy 5 (45) (48-97%), 3 (23) (32-99%), 6 (69) (45-86%), 3 (29) (45-98%), 4 (46) (47-93%), 3 (32) (47-97%), cardiogenic indication I2=75.4% I2=74.2% I2=71.7% I2=67.3% I2=69.2% I2=67% 79% 61% 41% 37% VAD support in post-cardiac surgery 4 (32) (43-99%), 6 (32) (29-88%), 5 (65) (30-54%), - - 2 (20) (3-82%), - - cardiogenic shock indication I2=62.3% I2= 65% I2= 0% I2= 78.4% 91% 84% 54% VAD support in post-transplant 3 (40) (35-100%), 2 (12) (23-100%), 3 (45) (39-68%), - - - - - - rejection or failure indication I2= 84.1% I2= 68% I2= 0% 87% 67% 40% VAD support in post-LVAD placement 6 (58) (70-97%), 4 (54) (38-91%), 3 (41) (2-88%), - - - - - - right ventricular failure indication I2= 57% I2=77.5% I2=90% Pts patients; VAD, ventricular assist device. –
Meta-analysis of and safety outcomes Table 7. Meta-analysis of effectiveness outcomes, survival (random-effect model) Indication Survival, percentage (95% confidence interval), I2 N studies (n pts) On support N studies (n pts) At discharge N studies (n pts) 30-day N studies (n pts) 90-day N studies (n pts) 6-month N studies (n pts) 1-year VAD support in pre-cardiotomy cardiogenic indication 5 (45) 78% (48-97%), I2=75.4% 3 (23) 75% (32-99%), I2=74.2% 6 (69) 67% (45-86%), I2=71.7% 3 (29) 78% (45-98%), I2=67.3% 4 (46) 73% (47-93%), I2=69.2% 3 (32) 78% (47-97%), I2=67% VAD support in post-cardiac surgery cardiogenic shock indication 4 (32) 79% (43-99%), I2=62.3% 6 (32) 61% (29-88%), I2= 65% 5 (65) 41% (30-54%), I2= 0% - - 2 (20) 37% (3-82%), I2= 78.4% - - VAD support in post-transplant rejection or failure indication 3 (40) 91% (35-100%), I2= 84.1% 2 (12) 84% (23-100%), I2= 68% 3 (45) 54% (39-68%), I2= 0% - - - - - - VAD support in post-LVAD placement right ventricular failure indication 6 (58) 87% (70-97%), I2= 57% 4 (54) 67% (38-91%), I2=77.5% 3 (41) 40% (2-88%), I2=90% - - - - - - Pts – patients; VAD, ventricular assist device.
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