The specificity of enzymes • 3 How enzymes work Describe the induced fit 3.1.4.2 Many Proteins are 3.3 Enzymes model of enzyme action Students should move on from the and key’ model they worked The induced-fit model of enzyme ‘lock with at GCSE and be able to action. describe the fit’ model. ‘induced There are several animations The properties of an enzyme available on the internet to relate to the tertiary structure of illustrate this concept. Students its active site and its ability to can make clay models to illustrate combine with complementary the lock and key and induced fit substrate(s) to form an models. substrate complex. Students should be able to: appreciate how models of • enzyme action have changed over time 4 Factors effecting Enzyme Describe the effects of 3.1.4.2 Many Proteins are 3.4 function concentration on enzyme Enzymes activity Focusing on enzyme and The effects of the following • concentration. Students could factors on the rate of enzyme complete a set of simple practical controlled reactions enzyme – activities to illustrate such as concentration, oxygen produced from catalase concentration, concentration of (from potatoes) and different competitive and of hydrogen peroxide inhibitors, pH and concentrations. temperature. 5 Factors effecting Enzyme Describe the effects of 3.1.4.2 Many Proteins are PS1.2 PS2.1 PS2.4 3.4 function temperature on the activity Enzymes of enzymes Focusing on temperature in The effects of the following • preparation for required practical. factors on the rate of enzyme You could show a piece of liver controlled reactions enzyme – (catalase) catalysing the concentration, breakdown of hydrogen peroxide concentration, concentration of and then heat the liver in a competitive and of Bunsen flame and repeat.
• The specificity of enzymes 3 How enzymes work Students should move on from the ‘lock and key’ model they worked with at GCSE and be able to describe the ‘induced fit’ model. There are several animations available on the internet to illustrate this concept. Students can make clay models to illustrate the lock and key and induced fit models. Describe the induced fit model of enzyme action 3.1.4.2 Many Proteins are Enzymes The induced-fit model of enzyme action. The properties of an enzyme relate to the tertiary structure of its active site and its ability to combine with complementary substrate(s) to form an complex. Students should be able to: • appreciate how models of enzyme action have changed over time 3.3 4 Factors effecting Enzyme function Focusing on enzyme and concentration. Students could complete a set of simple practical activities to illustrate such as oxygen produced from catalase (from potatoes) and different hydrogen peroxide concentrations. Describe the effects of concentration on enzyme activity 3.1.4.2 Many Proteins are Enzymes • The effects of the following factors on the rate of enzyme controlled reactions – enzyme concentration, concentration, concentration of competitive and of inhibitors, pH and temperature. 3.4 5 Factors effecting Enzyme function Focusing on temperature in preparation for required practical. You could show a piece of liver (catalase) catalysing the breakdown of hydrogen peroxide and then heat the liver in a Bunsen flame and repeat. Describe the effects of temperature on the activity of enzymes 3.1.4.2 Many Proteins are Enzymes • The effects of the following factors on the rate of enzyme controlled reactions – enzyme concentration, substrate concentration, concentration of competitive and of PS1.2 PS2.1 PS2.4 3.4
Biology%20SoW%20Year%201.docx