Agency for RMA ID: Toxicological Not reported Not reported Level of exposure: Not reported Report. Author’s Toxic (2001) 035227 Profile for 10 fibre are conclusion: asbestosis at Asbestos typically in a cubic prolonged exposures of metre (fibre/m3) of 5-20 fibre/mL rural outdoor air. corresponds to There is 1 million cumulative exposures of cm3 (or 1 million 50-200 fibre/mL-year for mL) in a cubic a 10 year exposure. metre so there Chronic exposure would be 0.00001 significantly increases fibre/mL of asbestosis mortality rates asbestos in rural in exposed workers with air. Air in the city is cumulative exposure of 10 fold higher. 32-1271 fibre/mL-year. Close to asbestos Cases of asbestosis with mines or factories very high asbestos air levels reach fibre and shorter latent 10,000 fibre/m3 periods (5-6 years) i.e. 0.01 fibre/mL. compared with latency of 10-20 years from studies of workers more recently exposed to lower fibre concentrations. Exposure durations (median 6-12 months) at 5-100 fibre/mL associated with pulmonary fibrosis. Burdorf & Roggli et al An Expert Not reported Not reported Not reported Not reported Historical Review. Swuste (1999) (2010) RMA System for the Author’s conclusion: a life ID: 067548 Evaluation Of time risk of asbestosis of Historical 2 per 1000 cases at 4.5 Asbestos fibre/mL-year. Evidence Exposure as of direct exposure to Diagnostic asbestos amounting to, or
Agency for Toxic (2001) RMA ID: 035227 Toxicological Profile for Asbestos Not reported Not reported Level of exposure: 10 fibre are typically in a cubic metre (fibre/m3) of rural outdoor air. There is 1 million cm3 (or 1 million mL) in a cubic metre so there would be 0.00001 fibre/mL of asbestos in rural air. Air in the city is 10 fold higher. Close to asbestos mines or factories levels reach 10,000 fibre/m3 i.e. 0.01 fibre/mL. Not reported Report. Author’s conclusion: asbestosis at prolonged exposures of 5-20 fibre/mL corresponds to cumulative exposures of 50-200 fibre/mL-year for a 10 year exposure. Chronic exposure significantly increases asbestosis mortality rates in exposed workers with cumulative exposure of 32-1271 fibre/mL-year. Cases of asbestosis with very high asbestos air fibre and shorter latent periods (5-6 years) compared with latency of 10-20 years from studies of workers more recently exposed to lower fibre concentrations. Exposure durations (median 6-12 months) at 5-100 fibre/mL associated with pulmonary fibrosis. Burdorf & Swuste (1999) Roggli et al (2010) RMA ID: 067548 An Expert System for the Evaluation Of Historical Asbestos Exposure as Diagnostic Not reported Not reported Not reported Not reported Historical Review. Author’s conclusion: a life time risk of asbestosis of 2 per 1000 cases at 4.5 fibre/mL-year. Evidence of direct exposure to asbestos amounting to, or
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