factors used to 3rd quartile. convert Cumulative fibre between the exposure (20 year lag) two and 8 hr showed statistically TWAs significant risk from 8.6 calculated. to <44.0 fibre/mL-year (n=25; RR=8.0, 95%CI: 3.2, 19.5) and fibre/mL-year ≥44.0 (n= 32, RR= 11.8, 95%CI: 4.9, 28.7) Authors conclusion: statistically significant association from 8.6 fibre/mL- year for deaths from asbestosis with significantly elevated SMR=142.8 for asbestosis. et al RMA ID: Exposure and 54 asbestos Chrysotile Cumulative Exposure Duration of Case- control study Asbestos (1997) 026469 Mineralogical workers asbestos exposure: assessment employment: examining exposure Correlates of necropsy textile N=54; method used N=54; relationship between producing Pulmonary reports (lung Median=30.2 (published range=0.1- chrysotile exposure asbestosis seen Fibrosis in tissue for 39 previously): >27.3 and pulmonary at 10-20 Raw asbestos Chrysotile workers) Linear fibrosis in a South Latency: predominantly Asbestos (44=men, fibre/mL-year statistical Carolina textile plant Median=30.0 from Quebec Workers 10=women) models for Asbestosis was with small reconstructing usually present in amounts from Men had historic dust asbestos textile 34 controls BC and larger exposure workers with >20 necropsy Zimbabwe; cumulative levels, taking reports (lung small exposures into account cumulative exposure tissue for 31 amounts of than women textile workers) crocidolite 34.6 and 25.6
factors used to convert between the two and 8 hr TWAs calculated. 3rd quartile. Cumulative fibre exposure (20 year lag) showed statistically significant risk from 8.6 to <44.0 fibre/mL-year (n=25; RR=8.0, 95%CI: 3.2, 19.5) and ≥44.0 fibre/mL-year (n= 32, RR= 11.8, 95%CI: 4.9, 28.7) Authors conclusion: statistically significant association from 8.6 fibre/mL- year for deaths from asbestosis with significantly elevated SMR=142.8 for asbestosis. et al (1997) RMA ID: 026469 Exposure and Mineralogical Correlates of Pulmonary Fibrosis in Chrysotile Asbestos Workers 54 asbestos workers necropsy reports (lung tissue for 39 workers) (44=men, 10=women) 34 controls necropsy reports (lung tissue for 31 workers) Chrysotile asbestos textile Raw asbestos predominantly from Quebec with small amounts from BC and Zimbabwe; small amounts of crocidolite Cumulative exposure: N=54; Median=30.2 fibre/mL-year Men had larger cumulative exposures than women 34.6 and 25.6 Exposure assessment method used (published previously): Linear statistical models for reconstructing historic dust exposure levels, taking into account textile Duration of employment: N=54; range=0.1- >27.3 Latency: Median=30.0 Case- control study examining relationship between chrysotile exposure and pulmonary fibrosis in a South Carolina textile plant Asbestosis was usually present in asbestos textile workers with >20 cumulative exposure Asbestos exposure producing asbestosis seen at 10-20
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