serology (use final symptoms: paroxysms of 21 days before the onset result POSITIVE - cut coughing; or inspiratory of symptoms. offs may differ; or flag "whoop”; or post-tussive if pertussis serology vomiting. done, and interpret at NICD). All ages. Tetanus Tuberculosis: pulmonary Tuberculosis: Tuberculosis: multidrug-resistant (MDR-TB) Tuberculosis: extensively resistant (XDR-TB) CATEGORY 3 NOTIFIABLE MEDICAL CONDITIONS To be notified through a written or electronic notification to the Department of Health within seven (7) days of diagnosis by private and public health laboratories Disease Short description Incubation CDW/lab case Suspected case Probable case Confirmed case period definition Endemic arboviral diseases chikungunya fever Chikungunya is caused by a 1- (2- 4) 12 Chikungunya virus or A person with acute A probable case is a A confirmed case is a person with virus transmitted by days alphavirus detected by onset of fever >38.5°C suspected case with laboratory evidence of mosquitoes (certain Aedes any test on any and severe arthralgia laboratory IgM chikungunya virus infection by species). Animal reservoirs specimen type *Exclude particularly in wrist and antibodies against (a.PCR positive and virus isolation of the virus include IgG serology and HAI ankles, with at least one chikungunya virus in the from the patient's first (single) monkeys, birds, cattle, and of the following signs absence of IgM to other specimen; OR b.PCR positive and rodents.No direct and symptoms alphaviruses. IgM positive result on patient's first transmission rash, headache, (single) specimen; OR c. PCR occurs.There are no vaccines myalgia AND having positive on two separate specimens to prevent infection with relevant epidemiological from the same patient collected at chikungunya virus and the exposure (Residing in least one day apart; OR d. PCR most effective protective area known to be positive but IgM/IgG negative measures are those that avoid endemic or having result in patient's first specimen mosquito bites. No specific travelled to chikungunya and PCR negative but IgM/IgG
serology (use final result POSITIVE - cut offs may differ; or flag if pertussis serology done, and interpret at NICD). All ages. symptoms: paroxysms of coughing; or inspiratory "whoop”; or post-tussive vomiting. 21 days before the onset of symptoms. Tetanus Tuberculosis: pulmonary Tuberculosis: Tuberculosis: multidrug-resistant (MDR-TB) Tuberculosis: extensively (XDR-TB) CATEGORY 3 NOTIFIABLE MEDICAL CONDITIONS To be notified through a written or electronic notification to the Department of Health within seven (7) days of diagnosis by private and public health laboratories Disease Short description Incubation period CDW/lab case definition Suspected case Probable case Confirmed case Endemic arboviral diseases chikungunya fever Chikungunya is caused by a virus transmitted by mosquitoes (certain Aedes species). Animal reservoirs of the virus include monkeys, birds, cattle, and rodents.No direct transmission occurs.There are no vaccines to prevent infection with chikungunya virus and the most effective protective measures are those that avoid mosquito bites. No specific 1- (2- 4) 12 days Chikungunya virus or alphavirus detected by any test on any specimen type *Exclude IgG serology and HAI A person with acute onset of fever >38.5°C and severe arthralgia particularly in wrist and ankles, with at least one of the following signs and symptoms rash, headache, myalgia AND having relevant epidemiological exposure (Residing in area known to be endemic or having travelled to chikungunya A probable case is a suspected case with laboratory IgM antibodies against chikungunya virus in the absence of IgM to other alphaviruses. A confirmed case is a person with laboratory evidence of chikungunya virus infection by (a.PCR positive and virus isolation from the patient's first (single) specimen; OR b.PCR positive and IgM positive result on patient's first (single) specimen; OR c. PCR positive on two separate specimens from the same patient collected at least one day apart; OR d. PCR positive but IgM/IgG negative result in patient's first specimen and PCR negative but IgM/IgG resistant
Appendix_C_NMC_case_definitions.docx