Bioequivalence - Single dose E2007-A001-008 * E2007-E044-016 * * E2007-A001-039 * * Bioequivalence - Multi-dose n/a Bioavailability - Single dose * E2007-E044-028 * Food effect Single dose E2007-E044-003 * – * PK in special Target population - Single n/a populations dose § - E2007-J081-231 Hepatic impairment E2007-E044-015 * Renal impairment n/a Paediatrics and adolescents n/a Elderly Single dose E2007-E044-007 * – E2007-E044-004 Poly-substance users E2007-A001-023 * E2007-A001-024 * Gender-related Males versus females E2007-E044-003 * PK PK interactions Ketoconazole * Carbamazepine E2007-E044-006 * Midazolam E2007-A001-014 * Oral contraceptives E2007-E044-019 * E2007-E044-029 * Levodopa E2007-E044-025 * Healthy subjects *
Bioequivalence - Single dose E2007-A001-008 E2007-E044-016 E2007-A001-039 * * * * * Bioequivalence - Multi-dose n/a Bioavailability - Single dose E2007-E044-028 * * Food effect – Single dose E2007-E044-003 * * PK in special populations Target population - Single dose n/a - E2007-J081-231 § Hepatic impairment E2007-E044-015 * Renal impairment n/a Paediatrics and adolescents n/a Elderly – Single dose E2007-E044-007 E2007-E044-004 * Poly-substance users E2007-A001-023 E2007-A001-024 * * Gender-related PK Males versus females E2007-E044-003 * PK interactions Ketoconazole * Carbamazepine E2007-E044-006 * Midazolam E2007-A001-014 * Oral contraceptives E2007-E044-019 E2007-E044-029 * * Levodopa E2007-E044-025 * Healthy subjects *
auspar-perampanel-141014.docx