Hamster Drug Dose and Frequency Notes Route Opioid analgesia Buprenorphine 0.05-0.1 Every 8-12 hours mg/kg SC Butorphanol 1-5 mg/kg SC Every 2-4 hours Non-steroidal anti-inflammatory analgesia (NSAID) Note that prolonged use may cause renal, – gastrointestinal, or other problems. Aspirin 240 mg/kg PO Every 24 hours Flunixin 2.5 mg/kg SC Every 12 24 Consult with Vet regarding repeated – hours administration. Local anesthetic/analgesics (Lidocaine and bupivacaine may be combined in one syringe for rapid onset and long duration analgesia) Bupivacaine 1-2mg/kg Before incision is Use as a local anesthetic, slow onset but max dose, made duration of action is 4-8 h. Do not give IV. mixed with Lidocaine at 1-4 mg/kg Lidocaine Lidocaine 1-4 mg/kg Before incision is Use as local anesthetic, fast onset but duration max dose, made of action is less than 1 h. mixed with bupivacaine at 1-2 mg/kg bupivacaine Rabbit Drug Dose and Frequency Notes Route Opioid analgesia Recommended: 0.05 0.1 Used pre- When used as sole analgesic, typical regimen is: – Buprenorphine mg/kg SC or operatively for once at time of procedure, second dose will be IP preemptive administered 4-6 hours later. Additional doses analgesia and every 8-12 hrs as needed. Consider multi-modal post-operatively analgesia with NSAID and local analgesic. 4-12 hrs Buprenorphine 1.0-2.0 mg/kg Give once for 72 SR SC hours Non-steroidal anti-inflammatory analgesia (NSAID) Note that prolonged use may cause renal, – gastrointestinal, or other problems.
Hamster Drug Dose and Route Frequency Notes Opioid analgesia Buprenorphine 0.05-0.1 mg/kg SC Every 8-12 hours Butorphanol 1-5 mg/kg SC Every 2-4 hours Non-steroidal anti-inflammatory analgesia (NSAID) – Note that prolonged use may cause renal, gastrointestinal, or other problems. Aspirin 240 mg/kg PO Every 24 hours Flunixin 2.5 mg/kg SC Every 12 – 24 hours Consult with Vet regarding repeated administration. Local anesthetic/analgesics (Lidocaine and bupivacaine may be combined in one syringe for rapid onset and long duration analgesia) Bupivacaine 1-2mg/kg max dose, mixed with Lidocaine at 1-4 mg/kg Lidocaine Before incision is made Use as a local anesthetic, slow onset but duration of action is 4-8 h. Do not give IV. Lidocaine 1-4 mg/kg max dose, mixed with bupivacaine at 1-2 mg/kg bupivacaine Before incision is made Use as local anesthetic, fast onset but duration of action is less than 1 h. Rabbit Drug Dose and Route Frequency Notes Opioid analgesia Recommended: Buprenorphine 0.05 – 0.1 mg/kg SC or IP Used pre- operatively for preemptive analgesia and post-operatively 4-12 hrs When used as sole analgesic, typical regimen is: once at time of procedure, second dose will be administered 4-6 hours later. Additional doses every 8-12 hrs as needed. Consider multi-modal analgesia with NSAID and local analgesic. Buprenorphine SR 1.0-2.0 mg/kg SC Give once for 72 hours Non-steroidal anti-inflammatory analgesia (NSAID) – Note that prolonged use may cause renal, gastrointestinal, or other problems.
Analgesics_in_Laboratory_Animals.docx