Appendix D. 2008 and 2014 French guidelines concerning targeted antibiotic prescriptions in urinary tract infections (UTIs). Clinical Alphabetical list of recommended antibiotics situation (choice to be adapted to antibiotic susceptibility data) 2014 guidelines [13] 2008 guidelines [13] First-line treatment Second-line First-line treatment treatment Acute Amoxicillin In decreasing In alphabetical complicateda order of order: cystitisb recommendation: Amoxicillin 1. Pivmecillinam Cefixime 2. Nitrofurantoin Co-amoxiclav 3. In alphabetical Cotrimoxazole Cefixime order: Nitrofurantoin or co-amoxiclav Pivmecillinamc or cotrimoxazole Quinolones:d or ciprofloxacin, fluoroquinolonesd enoxacin, (ciprofloxacin or lomefloxacin, ofloxacin) norfloxacin or 4. Oral fosfomycin ofloxacin (after expert advice) Acute Amoxicillin In alphabetical In alphabetical pyelonephritise order: order: Cefixime Amoxicillin Co-amoxiclav Cefixime Cotrimoxazole Co-amoxiclav Fluoroquinolones:d Cotrimoxazole ciprofloxacin, Fluoroquinolones:d levofloxacin or ciprofloxacin, ofloxacin levofloxacin or ofloxacin UTI in a male Fluoroquinolones:d Cotrimoxazole In alphabetical patiente ciprofloxacin, order: levofloxacin or Cotrimoxazole ofloxacin Fluoroquinolone:d ciprofloxacin, levofloxacin or ofloxacin a Only non-pregnant women with no known urological abnormalities or comorbidities are considered to have uncomplicated UTIs.
Appendix D. 2008 and 2014 French guidelines concerning targeted antibiotic prescriptions in urinary tract infections (UTIs). Clinical situation Alphabetical list of recommended antibiotics (choice to be adapted to antibiotic susceptibility data) 2014 guidelines [13] 2008 guidelines [13] First-line treatment Second-line treatment First-line treatment Acute complicateda cystitisb Amoxicillin In decreasing order of recommendation: 1. Pivmecillinam 2. Nitrofurantoin 3. In alphabetical order: Cefixime or co-amoxiclav or cotrimoxazole or fluoroquinolonesd (ciprofloxacin or ofloxacin) 4. Oral fosfomycin (after expert advice) In alphabetical order: Amoxicillin Cefixime Co-amoxiclav Cotrimoxazole Nitrofurantoin Pivmecillinamc Quinolones:d ciprofloxacin, enoxacin, lomefloxacin, norfloxacin or ofloxacin Acute pyelonephritise Amoxicillin In alphabetical order: Cefixime Co-amoxiclav Cotrimoxazole Fluoroquinolones:d ciprofloxacin, levofloxacin or ofloxacin In alphabetical order: Amoxicillin Cefixime Co-amoxiclav Cotrimoxazole Fluoroquinolones:d ciprofloxacin, levofloxacin or ofloxacin UTI in a male patiente Fluoroquinolones:d ciprofloxacin, levofloxacin or ofloxacin Cotrimoxazole In alphabetical order: Cotrimoxazole Fluoroquinolone:d ciprofloxacin, levofloxacin or ofloxacin a Only non-pregnant women with no known urological abnormalities or comorbidities are considered to have uncomplicated UTIs.
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