Li 2008a, To investigate Healthy nurses Blood and urine Primary measurement Forest Matching of participants Natural killer cell population and activity ↑ Japan the effect of a study aged 25-43 years, sampled for: Nk Perforin forest bathing selected with activity, numbers of ↑ (Li et al. trip on human informed consent NK and T cells, Granulysin 2008a) ↑ NK activity in granulysin, perforin, (n = 13) female subjects granzymes Granzymes A/B lymphotcytes ↑ expressing lymphotcytes, estradiol and progesterone concentration in serum, Adrenaline and noradrenaline concentration in urine. Phytoncides were also measured in the forest Li 2008b, To investigate Twelve healthy Blood and urine Primary measurement Forest Matching of participants Natural killer cell population and activity ↑ Japan the effect of study male subjects sampled for: Natural Level of perforin forest bathing aged 35-56 killer cell (NK) ↑ (Li et al. on NK activity activity, numbers of Granulysin 2008b) (n = 12) ↑ compared with a NK and T cells, trip to a city, and granulysin, perforin, Granzymes A/B lymphotcytes ↑ to measure how granzymes long the effect expressing Adrenaline concentration in ↓ on NK activity lymphotcytes, lasts adrenaline concentration in urine. Phytoncides were also measured in the forest
Li 2008a, Japan (Li et al. 2008a) To investigate the effect of a forest bathing trip on human NK activity in female subjects study Healthy nurses aged 25-43 years, selected with informed consent (n = 13) Blood and urine sampled for: Nk activity, numbers of NK and T cells, granulysin, perforin, granzymes lymphotcytes, estradiol and progesterone concentration in serum, Adrenaline and noradrenaline concentration in urine. Phytoncides were also measured in the forest Primary measurement Forest Matching of participants Natural killer cell population and activity ↑ Perforin ↑ Granulysin ↑ Granzymes A/B expressing lymphotcytes ↑ Li 2008b, Japan (Li et al. 2008b) To investigate the effect of forest bathing on NK activity compared with a trip to a city, and to measure how long the effect on NK activity lasts study Twelve healthy male subjects aged 35-56 (n = 12) Blood and urine sampled for: Natural killer cell (NK) activity, numbers of NK and T cells, granulysin, perforin, granzymes lymphotcytes, adrenaline concentration in urine. Phytoncides were also measured in the forest Primary measurement Forest Matching of participants Natural killer cell population and activity ↑ Level of perforin ↑ Granulysin ↑ Granzymes A/B expressing lymphotcytes ↑ Adrenaline concentration in ↓
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