Vascular endothelial growth Dual growth factor Solid nanofiber (130-150nm) Single Chitosan/PEO [] factor (VEGF)/ releasing needle/static derived growth factor-BB collector (PDGF-BB) system Keratinocytes fiber surface; Solid nanofiber (331±112nm/ Single needle Collagen/PCL [] collagen gel 55±26nm) syringe/static coating on mat collector NIH 3T3 fibroblast and Sandwich-type mat Solid nanofiber (no information Single needle; PCL [] primary rat skin cell consisting of about diameter ) rotating radially-aligned collector with nanofibers square arrayed (bottom),microskin wells; static tissue(middle) collector Nanofiber consisting of a membranes with ring electrode square-arrayed and a point microwells electrode and structural cues on the surface (top) Bone Hydroxyapatite NP/ Genipin (335 ±119 nm) Single needle/ Chitosan [] mouse 7F2 crosslinking; good static collector osteoblast-like cells mechanical property Hydroxyapatite NP/ human Biomimetic Solid (214±25 nm) Single Chitosan/PEO [] fetal osteoblast (hFOB) nanocomposite needle/static nanofibers collector Hydroxyapatite NP Good Solid fiber (several hundred Single needle/ PCL-PEG-PCL [] biocompatibility; nanometers~1 static collector μm) Guided bone regeneration in vivo BMP-2 and dexamethasone Dual-drug-loading; Solid nanofiber (350~400nm) Single PCE [] (DEX) sustained release; needle/static collector Hydroxyapatite NP/ Large pore size; Solid nanofiber (no information Single PCL/PEO/collagen [] mesenchymal stem high porosity and about diameter) needle/static (MSCs) pore collector interconnectivity Phase separation; Core/shell solid nanofiber Single Polyamide-6/ lactic acid []
Vascular endothelial growth factor (VEGF)/ growth factor-BB (PDGF-BB) Dual growth factor releasing system Solid nanofiber (130-150nm) Single needle/static collector Chitosan/PEO [] Keratinocytes fiber surface; collagen gel coating on mat Solid nanofiber (331±112nm/ 55±26nm) Single needle syringe/static collector Collagen/PCL [] NIH 3T3 fibroblast and primary rat skin cell Sandwich-type mat consisting of radially-aligned nanofibers (bottom),microskin tissue(middle) Nanofiber membranes with square-arrayed microwells and structural cues on the surface (top) Solid nanofiber (no information about diameter ) Single needle; rotating collector with square arrayed wells; static collector consisting of a ring electrode and a point electrode PCL [] Bone Hydroxyapatite NP/ mouse 7F2 osteoblast-like cells Genipin crosslinking; good mechanical property (335 ±119 nm) Single needle/ static collector Chitosan [] Hydroxyapatite NP/ human fetal osteoblast (hFOB) Biomimetic nanocomposite nanofibers Solid (214±25 nm) Single needle/static collector Chitosan/PEO [] Hydroxyapatite NP Good biocompatibility; Guided bone regeneration in vivo Solid fiber (several hundred nanometers~1 μm) Single needle/ static collector PCL-PEG-PCL [] BMP-2 and dexamethasone (DEX) Dual-drug-loading; sustained release; Solid nanofiber (350~400nm) Single needle/static collector PCE [] Hydroxyapatite NP/ mesenchymal stem (MSCs) Large pore size; high porosity and pore interconnectivity Solid nanofiber (no information about diameter) Single needle/static collector PCL/PEO/collagen [] Phase separation; Core/shell solid nanofiber Single Polyamide-6/ lactic acid [] derived
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