An infected REACTIVE and/or infant may be test on DNA An infant or child who Treponemapallidum asymptomatic serum/ blood (RPR or positive on PCR has a reactive at birth and rapid test POSITIVE) test for develop signs syphilis (RPR) AND 4-8 weeks any one of the after birth. following: Any evidence of congenital syphilis on physical examination: skin rash, jaundice, anaemia, mucosal lesions, nasal discharge Any evidence of congenital syphilis on x-ray of long bones: e.g. periostitis, tibial erosions An elevated cerebrospinal fluid (CSF) white cell count and protein (without other cause) A reactive cerebrospinal (CSF) venereal disease research laboratory test (VDRL) test
An infected infant may be asymptomatic at birth and develop signs 4-8 weeks after birth. REACTIVE test on serum/ blood (RPR or rapid test POSITIVE) An infant or child who has a reactive test for syphilis (RPR) AND any one of the following: Any evidence of congenital syphilis on physical examination: skin rash, jaundice, anaemia, mucosal lesions, nasal discharge Any evidence of congenital syphilis on x-ray of long bones: e.g. periostitis, tibial erosions An elevated cerebrospinal fluid (CSF) white cell count and protein (without other cause) A reactive cerebrospinal (CSF) venereal disease research laboratory test (VDRL) test and/or Treponemapallidum DNA positive on PCR
Appendix_C_NMC_case_definitions.docx