Definitions Commenced screening At one of the required components of the screening test was completed. Completed screening All the required components of each screening test were complete and a risk result was calculated. Required components of each screening test First trimester screening comprises analysis of two serum analytes (βhCG, PAPP-A) and a NT measurement. Second trimester screening comprises analysis of four serum analytes (βhCG, AFP, uE3 and Inhibin A). Low risk result A low risk result is defined as a risk lower than 1:300. So a risk of 1:310 is a low risk. Increased risk result An increased risk result is defined as a risk higher than or equal to 1:300. For some indicators increased risk screening results are further stratified into: 1:5 to 1:20 1:25 to 1:50 1:55 to 1:300. Inclusion criteria Women’s screens were included in this analysis if the following criteria were met: screening commencement date between 1 January 2011 and 31 December 2015 (ie, date of the first test the woman had as part of the screening pathway) valid National Health Index identifier (NHI) known District Health Board (DHB) of domicile age at screen from 12 to 49 years (calculated using the NHI database date of birth) single screening result per pregnancy. Data calculations DHB of domicile Each woman was allocated to a DHB based on the residential address recorded in the National Health Index (NHI). Where the NHI database did not have a DHB recorded for an NHI, information from the LabPLUS database was used to assign the DHB.
Definitions Commenced screening At one of the required components of the screening test was completed. Completed screening All the required components of each screening test were complete and a risk result was calculated. Required components of each screening test First trimester screening comprises analysis of two serum analytes (βhCG, PAPP-A) and a NT measurement. Second trimester screening comprises analysis of four serum analytes (βhCG, AFP, uE3 and Inhibin A). Low risk result A low risk result is defined as a risk lower than 1:300. So a risk of 1:310 is a low risk. Increased risk result An increased risk result is defined as a risk higher than or equal to 1:300. For some indicators increased risk screening results are further stratified into: 1:5 to 1:20 1:25 to 1:50 1:55 to 1:300. Inclusion criteria Women’s screens were included in this analysis if the following criteria were met: screening commencement date between 1 January 2011 and 31 December 2015 (ie, date of the first test the woman had as part of the screening pathway) valid National Health Index identifier (NHI) known District Health Board (DHB) of domicile age at screen from 12 to 49 years (calculated using the NHI database date of birth) single screening result per pregnancy. Data calculations DHB of domicile Each woman was allocated to a DHB based on the residential address recorded in the National Health Index (NHI). Where the NHI database did not have a DHB recorded for an NHI, information from the LabPLUS database was used to assign the DHB.
antenatal-screening-down-syndrome-other-conditions-monitoring-jan2011-dec2015-may17.docx