Show all fundamental steps for the mechanism of the following reaction. Show all fundamental steps for the mechanism of the following reaction. Show the reaction coordinate energy diagram for the following reaction with structures for all intermediates and transition states. On the same diagram use arrows up and down to indicate how the diagram would change when the meta product is formed instead. Explain the basis for the changes. versus Unlike methoxybenzene, acetoxybenzene does not readily undergo multiple substitutions. Show the product(s) and explain what factors determine which halogen transfers and the regiochemistry of substitution. Why aren’t there multiple substitutions on the same ester? Show the reaction coordinate energy diagram for the first reaction with structures for all intermediates and transition states. On the same diagram use arrows up and down to indicate how the reaction coordinate diagram (with structures) changes for the second reaction: bromination occurs for nitrobenezene. Explain the basis for the changes. versus (a) Predict favored mono-substitution product(s) for biphenyl. Explain your answer using structures as needed. (b) A single product is formed in the following reaction. Show the product and Explain. Explain the solvent effect for bromination of phenol. Show the mechanism and product for the following reaction Show the mechanism for the following reaction. the mechanism for the following reaction. the mechanism of the rearrangement of the following carbon 13 labeled compound.
Show all fundamental steps for the mechanism of the following reaction. Show all fundamental steps for the mechanism of the following reaction. Show the reaction coordinate energy diagram for the following reaction with structures for all intermediates and transition states. On the same diagram use arrows up and down to indicate how the diagram would change when the meta product is formed instead. Explain the basis for the changes. versus Unlike methoxybenzene, acetoxybenzene does not readily undergo multiple substitutions. Show the product(s) and explain what factors determine which halogen transfers and the regiochemistry of substitution. Why aren’t there multiple substitutions on the same ester? Show the reaction coordinate energy diagram for the first reaction with structures for all intermediates and transition states. On the same diagram use arrows up and down to indicate how the reaction coordinate diagram (with structures) changes for the second reaction: bromination occurs for nitrobenezene. Explain the basis for the changes. versus (a) Predict favored mono-substitution product(s) for biphenyl. Explain your answer using structures as needed. (b) A single product is formed in the following reaction. Show the product and Explain. Explain the solvent effect for bromination of phenol. Show the mechanism and product for the following reaction Show the mechanism for the following reaction. the mechanism for the following reaction. the mechanism of the rearrangement of the following carbon 13 labeled compound.
assignment-6-sykes-ch6-aromatic-substitution.docx