effect was very small (0.5mm) and no difference in skin temperature was found. Limitations: small trial, RISRAS measurements stopped when dry desquamation occurred, so effect on more severe skin reactions not assessed. No blinding of assessors and no allocation concealment. Silicone- Mepilex®Lite Randomised controlled Paterson, D., Mepilex®Lite dressings did + foam trial (patients as own Poonam, P., Bennett, not significantly reduce the Low adhesion control) comparing N., et al. 2012) incidence of moist Mepilex®Lite and Randomized desquamation, but reduced Aqueous cream BP on patient controlled trial the overall severity of skin first area of erythema to of Mepilex ®Lite reactions by 41% (p < 0.001) appear during radical RT dressings versus and the average moist to breast post Aqueous cream BP in desquamation score by 49% mastectomy. managing (p = 0.043). 80% of N=74 evaluable patients. skin reactions participants said they Outcomes: RISRAS, time postmastectomy. preferred the dressings over to moist desquamation, JCancer Sci Ther the cream and RISRAS time to healing 04:347-56. scores for pain/discomfort, itchiness, burning and effect on day to day life were NB preliminary results significantly better in the also reported in Mepilex®Lite area. Bennett N et al. 2013. Proceedings from RTi3 2013: Inquire, Limitations: study only Inspire, compared dressings applied
effect was very small (0.5mm) and no difference in skin temperature was found. Limitations: small trial, RISRAS measurements stopped when dry desquamation occurred, so effect on more severe skin reactions not assessed. No blinding of assessors and no allocation concealment. Silicone- foam Low adhesion Mepilex®Lite Randomised controlled trial (patients as own control) comparing Mepilex®Lite and Aqueous cream BP on first area of erythema to appear during radical RT to breast post mastectomy. N=74 evaluable patients. Outcomes: RISRAS, time to moist desquamation, time to healing Paterson, D., Poonam, P., Bennett, N., et al. 2012) Randomized controlled trial of Mepilex ®Lite dressings versus Aqueous cream BP in managing skin reactions postmastectomy. JCancer Sci Ther 04:347-56. NB preliminary results also reported in Bennett N et al. 2013. Proceedings from RTi3 2013: Inquire, Inspire, Mepilex®Lite dressings did not significantly reduce the incidence of moist desquamation, but reduced the overall severity of skin reactions by 41% (p < 0.001) and the average moist desquamation score by 49% (p = 0.043). 80% of participants said they preferred the dressings over the cream and RISRAS scores for pain/discomfort, itchiness, burning and effect on day to day life were significantly better in the Mepilex®Lite area. Limitations: study only compared dressings applied + patient
appendix_9_-_dressings_table.docx