eModel. Predictive model of psychosis transition in ARMS+ only (n=67) Predictor Wald Hazard AUCa (SE) P SE Sensitivity Specificity R2N β Variable Ratio Value [95% CI] X2 Avolition>3 1.340 0.52 6.66 3.82 0.010 (CAARMS) Sensory 0.868 (0.060) 1.673 0.65 6.68 5.33 0.010 0.495 0.765 0.920 Integration>2 [0.751-0.984] (NES) Faux Pas<16 1.305 0.52 6.37 3.69 0.012 Positive predictive value (PPV): 81.25% Potential Predictor Domains and Individual Variables for the Cox ARMS+ only (n=67). Proportional Hazard Model to Psychosis”. “Transition Variables Retained Variables Retained after Univariable After Multivariate Domain Variables screening procedure Cox Regression Final Model for to Across Domains, “Transition Psychosis” (p<.10) Blockwise (p<.15) -Age at baseline -Education (years) None Demographics -Gender -Employment Diagnosis: -Any mood disorder -Any anxiety disorder -Any personality disorder -Multiple diagnoses Risk Status : Clinical Risk Status: information APS BLIPS BLIPS GRD -Duration of illness (years) -Medication exposure at baseline
eModel. Predictive model of psychosis transition in ARMS+ only (n=67) Predictor Variable β SE Wald X2 Hazard Ratio P Value AUCa (SE) [95% CI] R2N Sensitivity Specificity Avolition>3 (CAARMS) 1.340 0.52 6.66 3.82 0.010 Sensory Integration>2 (NES) 1.673 0.65 6.68 5.33 0.010 0.868 (0.060) [0.751-0.984] 0.495 0.765 0.920 Faux Pas<16 1.305 0.52 6.37 3.69 0.012 Positive predictive value (PPV): 81.25% ARMS+ only (n=67). Potential Predictor Domains and Individual Variables for the Cox Proportional Hazard Model “Transition to Psychosis”. Domain Variables Variables Retained after Univariable screening procedure for “Transition to Psychosis” (p<.10) Variables Retained After Multivariate Cox Regression Across Domains, Blockwise (p<.15) Final Model Demographics -Age at baseline -Education (years) -Gender -Employment None Clinical information Diagnosis: -Any mood disorder -Any anxiety disorder -Any personality disorder -Multiple diagnoses Risk Status: APS BLIPS GRD -Duration of illness (years) -Medication exposure at baseline Risk Status : BLIPS
1-s2.0-S0924933816301365-mmc1.docx