only present on ratios to express the severity of the disorder (see outcomes. Describe the one chromosome. resources). Video clip: genotypes and phenotypes of A recessive allele Evaluate genetic modification the offspring. is only expressed to treat cystic fibrosis. if present on both Produce notes and complete chromosomes. genetic diagrams to explain If the two alleles how polydactyly and cystic present are the fibrosis are inherited. same the person Interpret genetic diagrams is homozygous for relating to these disorders. that trait, but if the Role play choices for parents – alleles are of a cystic fibrosis sufferer who different they are Describe the inherited would like another child. To heterozygous. disorders polydactyly and involve experts explaining cystic fibrosis. Most cystic fibrosis and the 4.6.1.6 Video clip: Use genetic diagrams to characteristics are screening procedure; the child explain inheritance and 4.6.1.7 a result of multiple with the disorder; parents to carriers. genes interacting. discuss what they would do if Make informed judgements the foetus had the disorder. Some disorders about the economic, social are inherited, eg and ethical issues concerning Or polydactyly and embryo screening. Watch a video of the process cystic fibrosis. Discuss the use of genetic and describe issues to be modification to genetic A Punnett square considered re embryo disorders (links with 4.6.1.4). can be screening. constructed to HT: construct Punnet squares and genetic crosses. predict the
4.6.1.6 4.6.1.7 only present on one chromosome. A recessive allele is only expressed if present on both chromosomes. If the two alleles present are the same the person is homozygous for that trait, but if the alleles are different they are heterozygous. Most characteristics are a result of multiple genes interacting. Some disorders are inherited, eg polydactyly and cystic fibrosis. A Punnett square can be constructed to predict the ratios to express the outcomes. Describe the genotypes and phenotypes of the offspring. Describe the inherited disorders polydactyly and cystic fibrosis. Use genetic diagrams to explain inheritance and carriers. Make informed judgements about the economic, social and ethical issues concerning embryo screening. Discuss the use of genetic modification to genetic disorders (links with 4.6.1.4). HT: construct Punnet squares and genetic crosses. severity of the disorder (see resources). Evaluate genetic modification to treat cystic fibrosis. Produce notes and complete genetic diagrams to explain how polydactyly and cystic fibrosis are inherited. Interpret genetic diagrams relating to these disorders. Role play – choices for parents of a cystic fibrosis sufferer who would like another child. To involve experts explaining cystic fibrosis and the screening procedure; the child with the disorder; parents to discuss what they would do if the foetus had the disorder. Or Watch a video of the process and describe issues to be considered re embryo screening. Video clip: Video clip:
AQA-8461-SOW-IVE.DOCX