activating factor. Delayed Several hour delay Related to Related to tick Beef, pork, Uncertain Serum test for food following ingestion antibodies to lamb IgE to alpha-gal anaphylaxis carbohydrate SPT and/or sIgE to moiety mammalian (see text) meats Food triggers Exercise is Onset more Wheat, Presumed SPT and/or sIgE anaphylaxis only if presumed to commonly later shellfish celery persistent Component ingestion followed alter gut childhood/adult most testing induced temporally by exercise. absorption described. anaphylaxis and or Exercise test allergen (may be poorly digestion. reproducible) IgE antibody mediated Atopic Associated with food in May relate to Major Typically SPT and/or sIgE dermatitis ~35% of children with homing of allergens, resolves APT not generally moderate-severe rash. particularly recommended egg, milk. T-cells to the skin.
activating factor. Delayed food anaphylaxis to mammalian meats Several hour delay following ingestion Related to antibodies to carbohydrate moiety (see text) Related to tick Beef, pork, lamb Uncertain Serum test for IgE to alpha-gal SPT and/or sIgE anaphylaxis Food triggers anaphylaxis only if ingestion followed temporally by exercise. Exercise is presumed to alter gut absorption and or allergen digestion. Onset more commonly later childhood/adult Wheat, shellfish celery most described. Presumed persistent SPT and/or sIgE Component testing Exercise test (may be poorly reproducible) IgE antibody mediated Atopic dermatitis Associated with food in ~35% of children with moderate-severe rash. May relate to homing of T-cells to the skin. Major allergens, particularly egg, milk. Typically resolves SPT and/or sIgE APT not generally recommended induced
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