6 HIV and the immune system Recall the cellular and 3.2.4 Cell recognition and the 7.3 humoral immune response immune system 7.4 Using a card sort students could Describe the structure of HIV recall previous lessons and put Explain how HIV replicates Structure of the human together a flow chart of the and how it can be treated immunodeficiency virus (HIV) and cellular and humoral immune its replication in helper T cells. response. Students recall prior knowledge of the structure of a How HIV causes the symptoms of virus and relate it to the structure AIDS. Why antibiotics are of HIV. Working in pairs or ineffective against viruses. independently students could research and create a poster/presentation to meet the lesson objectives on HIV. 7 Monoclonal antibodies Define the term monoclonal 3.2.4 Cell recognition and the MS 3.1 Translate 7.5 antibody immune system information between Students could try and define a Explain how monoclonal graphical, numerical and monoclonal antibody in less than antibodies can be used in The use of monoclonal antibodies algebraic forms 20 words. A flow chart can be diagnostic testing in: created or modelled to describe Discuss the ethics targeting medication to specific PS 1.2 scientific • how monoclonal antibodies are surrounding vaccination cell by attaching a therapeutic knowledge to practical used in ELISA tests. Assignment 4 programmes, the use of drug to an antibody contexts can be used to frame discussion monoclonal antibodies in medical diagnosis. • surrounding the ethics of using diagnostic testing and use of PS 2.1 Comment on antibiotics. antibiotics Details of the production of experimental design and monoclonal antibodies is not evaluate scientific methods required. PS 2.2Present data in Ethical issues associated with the appropriate ways use of vaccines and monoclonal antibodies. The use of antibodies PS 2.3 Evaluate results and in the ELISA test. draw conclusions with reference to measurement Students should be able to: uncertainties and errors discuss ethical issues associated PS 3.1Plot and interpret • with the use of vaccines and graphs monoclonal antibodies
6 HIV and the immune system Using a card sort students could recall previous lessons and put together a flow chart of the cellular and humoral immune response. Students recall prior knowledge of the structure of a virus and relate it to the structure of HIV. Working in pairs or independently students could research and create a poster/presentation to meet the lesson objectives on HIV. Recall the cellular and humoral immune response Describe the structure of HIV Explain how HIV replicates and how it can be treated 3.2.4 Cell recognition and the immune system Structure of the human immunodeficiency virus (HIV) and its replication in helper T cells. How HIV causes the symptoms of AIDS. Why antibiotics are ineffective against viruses. 7.3 7.4 7 Monoclonal antibodies Students could try and define a monoclonal antibody in less than 20 words. A flow chart can be created or modelled to describe how monoclonal antibodies are used in ELISA tests. Assignment 4 can be used to frame discussion surrounding the ethics of using antibiotics. Define the term monoclonal antibody Explain how monoclonal antibodies can be used in diagnostic testing Discuss the ethics surrounding vaccination programmes, the use of monoclonal antibodies in diagnostic testing and use of antibiotics 3.2.4 Cell recognition and the immune system The use of monoclonal antibodies in: • targeting medication to specific cell by attaching a therapeutic drug to an antibody • medical diagnosis. Details of the production of monoclonal antibodies is not required. Ethical issues associated with the use of vaccines and monoclonal antibodies. The use of antibodies in the ELISA test. Students should be able to: • discuss ethical issues associated with the use of vaccines and monoclonal antibodies MS 3.1 Translate information between graphical, numerical and algebraic forms PS 1.2 scientific knowledge to practical contexts PS 2.1 Comment on experimental design and evaluate scientific methods PS 2.2Present data in appropriate ways PS 2.3 Evaluate results and draw conclusions with reference to measurement uncertainties and errors PS 3.1Plot and interpret graphs 7.5
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