APPENDIX 3 - EXAMPLE OF A COMPLETED PART A, INCLUDING REPORTING OF SPECIFIED ANIMAL BREEDING STOCK In 2016 licence SPPL301 used mice and rats (specified animals), and fish in 2 AEC-approved projects (Projects 00061 and 00046). In addition, the licence bred mice and rats (specified animals) for use by the licence. The following table illustrates how the animal use procedures and the breeding of specified animals is to be described. The inclusion of numbers’ are illustrative only and should not be ‘group included in the submitted worksheet. A B C D E F G H I J K L M Year Licence Project or AEC project AEC Type Source Purpose of Benefit focus of Particular Impact on animals Total All no. Specified Animal identification of animal use animal use procedure used deaths Breeding Colony code date animal Maintenance AEC-approved Own Diseases Animal unconscious without 1 2016 301 00061 Mice human health Other procedure 20 20 project 0 derivation human recovery etc Maintenance AEC-approved Own Animal unconscious without 2 2016 301 00061 Rats human health Diseases Other procedure 75 75 project 0 derivation recovery etc Maintenance AEC-approved Own Diseases 3 2016 301 00061 Rats human health Other procedure Observational study etc 10 project derivation human etc AEC-approved Commercial Understanding Fundamental Animal unconscious without 1 2016 301 00046 Fish Other procedure 19 19 project supplier biology etc biology etc recovery AEC-approved Commercial Understanding Fundamental 2 2016 301 00046 Fish Other procedure Minor Physiological challenge 5 project supplier biology etc biology etc AEC-approved Own Understanding Fundamental Animal unconscious without 3 2016 301 00046 Mice procedure 5 5 project derivation biology etc biology etc recovery Specified Specified Specified Specified Animal Own Animal Animal Animal Specified Animal Breeding 1 2016 301 SABC N/A Mice 5,235 293 Breeding Colony derivation Breeding Breeding Breeding Colony (non-GM) Colony Colony Colony Specified Specified Specified Specified Animal Own Animal Animal Animal Specified Animal Breeding 2 2016 301 SABC N/A Mice 1,987 183 Breeding Colony derivation Breeding Breeding Breeding Colony established GM line Colony Colony Colony Specified Specified Specified Specified Animal Own Animal Animal Animal Specified Animal Breeding 3 2016 301 SABC N/A Rats 3,896 221 Breeding Colony derivation Breeding Breeding Breeding Colony established GM line Colony Colony Colony
APPENDIX 3 - EXAMPLE OF A COMPLETED PART A, INCLUDING REPORTING OF SPECIFIED ANIMAL BREEDING STOCK In 2016 licence SPPL301 used mice and rats (specified animals), and fish in 2 AEC-approved projects (Projects 00061 and 00046). In addition, the licence bred mice and rats (specified animals) for use by the licence. The following table illustrates how the animal use procedures and the breeding of specified animals is to be described. The inclusion of ‘group numbers’ are illustrative only and should not be included in the submitted worksheet. A Year B Licence no. C Project or Specified Animal Breeding Colony D AEC project identification code E AEC date F Type of animal G Source H Purpose of animal use I Benefit focus of animal use J Particular procedure K Impact on animals L Total used M All deaths 1 2016 301 AEC-approved project 00061 Mice Own derivation Maintenance human health etc Diseases human Other procedure Animal unconscious without recovery 20 20 2 2016 301 AEC-approved project 00061 Rats Own derivation Maintenance human health etc Diseases Other procedure Animal unconscious without recovery 75 75 3 2016 301 AEC-approved project 00061 Rats Own derivation Maintenance human health etc Diseases human Other procedure Observational study etc 10 0 1 2016 301 AEC-approved project 00046 Fish Commercial supplier Understanding biology etc Fundamental biology etc Other procedure Animal unconscious without recovery 19 19 2 2016 301 AEC-approved project 00046 Fish Commercial supplier Understanding biology etc Fundamental biology etc Other procedure Minor Physiological challenge 5 0 3 2016 301 AEC-approved project 00046 Mice Own derivation Understanding biology etc Fundamental biology etc procedure Animal unconscious without recovery 5 5 1 2016 301 Specified Animal Breeding Colony SABC N/A Mice Own derivation Specified Animal Breeding Colony Specified Animal Breeding Colony Specified Animal Breeding Colony Specified Animal Breeding Colony (non-GM) 5,235 293 2 2016 301 Specified Animal Breeding Colony SABC N/A Mice Own derivation Specified Animal Breeding Colony Specified Animal Breeding Colony Specified Animal Breeding Colony Specified Animal Breeding Colony established GM line 1,987 183 3 2016 301 Specified Animal Breeding Colony SABC N/A Rats Own derivation Specified Animal Breeding Colony Specified Animal Breeding Colony Specified Animal Breeding Colony Specified Animal Breeding Colony established GM line 3,896 221
Animal-Use-Return-2016-Guidelines.docx