High density lipoproteins are solely responsible for cholesterol excretion All cholesterol is transported in the esterified form. A patient with Von Gierke’s disease (Glycogen storage disease Type I) is admitted to the hospital suffering severe metabolic acidosis. Which of the following probably contributed to the severe acidosis? A) Over production of lactic acid caused by increased glycolysis B) Over production of ketone bodies as the patient turns to fat stores for energy C) Decreased uric acid excretion caused by transporter competition with lactic acid D) A and B E) All of the above of the following statements regarding chylomicrons is correct? Chylomicrons are synthesized and stored in the gall bladder Chylomicrons can transport triacylglycerides but not phospholipids or lipid soluble vitamins Chylomicrons are considered the most dense lipoprotein in human plasma Chylomicrons are the only lipoprotein that express apoprotein E Hyperchylomicronemia can be caused by a deficiency in lipoprotein lipases Which of the following correctly describes the regulation of the synthesis and uptake of cholesterol? A) Insulin activates HMG-CoA reductase via a phosphatase. B) Cholesterol increases HMG-CoA reductase gene expression. C) Cholesterol will increase the expression of low density lipoproteins. D) Cholesterol will decrease the rate of breakdown of HMG CoA reductase. E) Cholic acid and cholesterol have opposite regulatory effects on HMG-CoA Reductase. 30) How will high concentrations of AMP, citrate and fructose 2,6-bisphosphate, respectively, tend to affect the rate of glycolysis? AMP citrate fructose 2,6-bisphosphate A) increase increase increase B) increase decrease increase C) decrease increase increase D) decrease decrease increase E) decrease increase decrease 31) Which of the following correctly describes the malate-aspartate shuttle? A) During gluconeogenesis malate is moving into the cytoplasm
High density lipoproteins are solely responsible for cholesterol excretion All cholesterol is transported in the esterified form. A patient with Von Gierke’s disease (Glycogen storage disease Type I) is admitted to the hospital suffering severe metabolic acidosis. Which of the following probably contributed to the severe acidosis? A) Over production of lactic acid caused by increased glycolysis B) Over production of ketone bodies as the patient turns to fat stores for energy C) Decreased uric acid excretion caused by transporter competition with lactic acid D) A and B E) All of the above of the following statements regarding chylomicrons is correct? Chylomicrons are synthesized and stored in the gall bladder Chylomicrons can transport triacylglycerides but not phospholipids or lipid soluble vitamins Chylomicrons are considered the most dense lipoprotein in human plasma Chylomicrons are the only lipoprotein that express apoprotein E Hyperchylomicronemia can be caused by a deficiency in lipoprotein lipases Which of the following correctly describes the regulation of the synthesis and uptake of cholesterol? A) Insulin activates HMG-CoA reductase via a phosphatase. B) Cholesterol increases HMG-CoA reductase gene expression. C) Cholesterol will increase the expression of low density lipoproteins. D) Cholesterol will decrease the rate of breakdown of HMG CoA reductase. E) Cholic acid and cholesterol have opposite regulatory effects on HMG-CoA Reductase. 30) How will high concentrations of AMP, citrate and fructose 2,6-bisphosphate, respectively, tend to affect the rate of glycolysis? AMP citrate fructose 2,6-bisphosphate A) increase increase increase B) increase decrease increase C) decrease increase increase D) decrease decrease increase E) decrease increase decrease 31) Which of the following correctly describes the malate-aspartate shuttle? A) During gluconeogenesis malate is moving into the cytoplasm
B514ExamII_Form12A.docx