PBS-listed for outside outside Aus and June Dec Temozolomide 6 Yes 7 None funding April 2006 funding NZ 1999 1998 restrictions restrictions multiforme Metastatic no June no Temsirolimus Torisel® Aus 4 Yes renal cell 22 None no funding no funding 2008 in July registration carcinoma 2008 not no Soft tissue sponsor No PBAC no no Trabectedin Aus 2 No 0 None no funding sarcoma application registration registration In combination with dabrafenib for no treatment of March Aus and Feb March Trametinib Mekinist® 24 Yes BRAF V600 106 None 2014, no funding no funding NZ 2014 2015 no mutation funding positive Nov 2014 Stage 3 or metastatic melanoma
Temozolomide Aus and NZ 6 Yes 7 None June 1999 PBS-listed for multiforme outside funding restrictions Dec 1998 April 2006 outside funding restrictions Temsirolimus Torisel® Aus 4 Yes Metastatic renal cell carcinoma 22 None June 2008 in July 2008 no funding no no funding no registration Trabectedin Aus 2 No Soft tissue sarcoma 0 None not sponsor No PBAC application no registration no no funding no registration Trametinib Mekinist® Aus and NZ 24 Yes In combination with dabrafenib for treatment of BRAF V600 mutation positive Stage 3 or metastatic melanoma 106 None Feb 2014 March 2014, Nov 2014 no funding March 2015 no funding no no funding
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