A3. Lifestyle recommendations for total CVD risk reduction in 6 Guidelines Organization National Institute European Society National Vascular American College Centers for British Cardiovascular responsible for for Health and Care of Cardiology Disease Prevention of Cardiology/ Disease Control Society (BCS) guideline Excellence (NICE) (ESC) alliance (NVDP) American and Prevention/ development Heart Association American Heart (ACC/AHA) Association (CDC/ AHA) Country applied UK EUR Australia USA USA UK Year 2014 2016 2012 2013 2011 2014 AGREE II rigor 86% 86% 85% 83% 65% 45% Score % Methods used to Systematic review Systematic review Systematic review Systematic review Systematic review Review evaluate evidence Formal consensus Formal consensus Formal consensus Formal consensus Formal consensus NR Methods used to formulate and voting Persons aged 40-74 Men > 40-y, All adults aged Persons aged 21 Women 20 y Children and adults Target Group ≥ ≥ (NHS Health >50-y or >45 y or Aboriginal Check) and Torres Strait Islanders aged >35 y Intensive If 10-y CHD/ If 10-y CVD If 5-y CHD/stroke If 10-y CHD/ NR If Diabetes, age >40 Lifestyle stroke/ TIA risk mortality >1% or risk stroke risk years, CKD stages ≤10%. ≥7.5% Counselling LDL-C If 5-y CHD/stroke and LDL-C 70-189 Familial ≥10% >100mg/dL. risk more mg/dL; DM1 or Hypercholesterolaemia ≥10%; frequent and DM2; LDL-C level or high short term risk sustained lifestyle mg/dL. as per NICE 2014 (i.e. ≥190 interventions. QRISK2 ≥10%)
A3. Lifestyle recommendations for total CVD risk reduction in 6 Guidelines Organization responsible for guideline development National Institute for Health and Care Excellence (NICE) European Society of Cardiology (ESC) National Vascular Disease Prevention alliance (NVDP) American College of Cardiology/ American Heart Association (ACC/AHA) Centers for Disease Control and Prevention/ American Heart Association (CDC/ AHA) British Cardiovascular Society (BCS) Country applied UK EUR Australia USA USA UK Year 2014 2016 2012 2013 2011 2014 AGREE II rigor Score % 86% 86% 85% 83% 65% 45% Methods used to evaluate evidence Systematic review Systematic review Systematic review Systematic review Systematic review Review Methods used to formulate Formal consensus Formal consensus Formal consensus Formal consensus Formal consensus and voting NR Target Group Persons aged 40-74 (NHS Health Check) Men > 40-y, >50-y or All adults aged >45 y or Aboriginal and Torres Strait Islanders aged >35 y Persons aged ≥ 21 Women ≥ 20 y Children and adults Intensive Lifestyle Counselling If 10-y CHD/ stroke/ TIA risk ≥10% If 10-y CVD mortality >1% or LDL-C >100mg/dL. If 5-y CHD/stroke risk ≤10%. If 5-y CHD/stroke risk ≥10%; more frequent and sustained lifestyle interventions. If 10-y CHD/ stroke risk ≥7.5% and LDL-C 70-189 mg/dL; DM1 or DM2; LDL-C level ≥190 mg/dL. NR If Diabetes, age >40 years, CKD stages Familial Hypercholesterolaemia or high short term risk as per NICE 2014 (i.e. QRISK2 ≥10%)
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