Metabolism and Nutrition 8.2 2.6 Disorders Musculoskeletal and Connective 5.5 3.8 Tissue 4.1 7.7 Disorders Muscle spasms Pain in extremity Nervous System 8.2 3.8 Disorders 4.1 5.1 Dizziness Headache Respiratory, Thoracic and 5.5 3.8 Mediastinal Disorders Cough The most frequently occurring (≥ 2% of patients) undesirable effects possibly or probably related to sevelamer were mainly in the gastrointestinal disorders system organ class (Table 6). Most of these adverse reactions were mild to moderate in intensity. Table 6 Adverse Reactions in Studies GD3-163-201 (N=73), SVCARB00205 (N=31), and SVCARB00105 (N=49) in CIOMS format System Organ Class Common (≥ 1/100 to <1/10 ) Nausea Constipation Vomiting Gastrointestinal Disorders Abdominal pain upper Diarrhoea
Metabolism and Nutrition Disorders 8.2 2.6 Musculoskeletal and Connective Tissue Disorders Muscle spasms Pain in extremity 5.5 4.1 3.8 7.7 Nervous System Disorders Dizziness Headache 8.2 4.1 3.8 5.1 Respiratory, Thoracic and Mediastinal Disorders Cough 5.5 3.8 The most frequently occurring (≥ 2% of patients) undesirable effects possibly or probably related to sevelamer were mainly in the gastrointestinal disorders system organ class (Table 6). Most of these adverse reactions were mild to moderate in intensity. Table 6 Adverse Reactions in Studies GD3-163-201 (N=73), SVCARB00205 (N=31), and SVCARB00105 (N=49) in CIOMS format System Organ Class Common (≥ 1/100 to <1/10 ) Nausea Constipation Vomiting Gastrointestinal Disorders Abdominal pain upper Diarrhoea
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