Supplementary 1 Calibration curve parameters and repeatability Calibration curve parameters 20 degrees Mepivacaine 95% Lidocaine 95% Bupivacaine 95% Methylparaben 95% of freedom CI CI CI CI Slope 6525 154 5904 154 5495 28 10250 465 (mL/mg) intercept -7.8 6.8 2.8 6.8 -5.8 1.2 -0.5 1.01 0.9981 0.9977 0.9999 0.9930 r 2 0.9991 0.9989 1.0000 0.9965 r Repeatability, three levels C1, 0.28 0.50 0.33 4.66 n=6 % % % C3, 0.22 0.28 0.17 3.08 % n=6 RSD RSD RSD RSD C5, 0.63 0.46 0.29 0.29 n=6 CI, Confidence intervals; correlation coefficient; 2: Degree of explanation; RSD, Relative standard deviation. r, r
Supplementary 1 Calibration curve parameters and repeatability Calibration curve parameters 20 degrees of freedom Mepivacaine 95% CI Lidocaine 95% CI Bupivacaine 95% CI Methylparaben 95% CI Slope (mL/mg) 6525 154 5904 154 5495 28 10250 465 intercept -7.8 6.8 2.8 6.8 -5.8 1.2 -0.5 1.01 r 0.9981 0.9977 0.9999 0.9930 r 2 0.9991 0.9989 1.0000 0.9965 Repeatability, three levels C1, n=6 0.28 % RSD 0.50 % RSD 0.33 % RSD 4.66 C3, n=6 0.22 0.28 0.17 3.08 % RSD C5, n=6 0.63 0.46 0.29 0.29 CI, Confidence intervals; r, correlation coefficient; r 2: Degree of explanation; RSD, Relative standard deviation.
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