or following overdosage DBL Ephedrine Sulfate with ganglionic-blocking Injection has also been agents, antiadrenergic used in the treatment of agents, veratrum bronchial asthma and alkaloids or other drugs reversible bronchospasm used for lowering blood although more selective pressure in the treatment agents (beta adrenergic of arterial hypertension. agonists) are now The drug is sometimes available. injected to relieve acute bronchospasm, but it is less effective than epinephrine for this purpose. General dosage Depending on the clinical NA DBL Ephedrine Sulfate instructions circumstances, Ephedrine Injection is administered Sulfate Injection may be by the intramuscular, given subcutaneously, subcutaneous or intramuscularly or intravenous Patients intravenously. in shock may require intravenous administration to ensure absorption of the drug. When administered intravenously, the injection should be given slowly. Care should be taken to avoid extravasation, since this may result in tissue necrosis and sloughing. Ephedrine sulfate should be administered in the lowest effective dose. The parenteral adult dose should not exceed 150 mg in 24 hours. Adult dose for 25 to 50 mg (range 10 to Up to 30 mg in increments The usual adult dose is 25 hypotension 50 mg) injected of 3 to 7.5 mg. After the to 50 mg (range 10 to 50 subcutaneously or development of mg) administered intramuscularly hypotension, by slow intramuscularly or (equivalent to 0.2 to 1.0 intravenous subcutaneously. mL of 5% solution) is administration. Additional doses should usually adequate to be based on patient prevent or minimize response. The intravenous hypotension secondary to route may be used if an spinal anaesthesia. Repeat immediate response is doses should be governed required. The dosage for the intravenous route is
or following overdosage with ganglionic-blocking agents, antiadrenergic agents, veratrum alkaloids or other drugs used for lowering blood pressure in the treatment of arterial hypertension. The drug is sometimes injected to relieve acute bronchospasm, but it is less effective than epinephrine for this purpose. DBL Ephedrine Sulfate Injection has also been used in the treatment of bronchial asthma and reversible bronchospasm although more selective agents (beta adrenergic agonists) are now available. General dosage instructions Depending on the clinical circumstances, Ephedrine Sulfate Injection may be given subcutaneously, intramuscularly or intravenously. NA DBL Ephedrine Sulfate Injection is administered by the intramuscular, subcutaneous or intravenous Patients in shock may require intravenous administration to ensure absorption of the drug. When administered intravenously, the injection should be given slowly. Care should be taken to avoid extravasation, since this may result in tissue necrosis and sloughing. Ephedrine sulfate should be administered in the lowest effective dose. The parenteral adult dose should not exceed 150 mg in 24 hours. Adult dose for hypotension 25 to 50 mg (range 10 to 50 mg) injected subcutaneously or intramuscularly (equivalent to 0.2 to 1.0 mL of 5% solution) is usually adequate to prevent or minimize hypotension secondary to spinal anaesthesia. Repeat doses should be governed Up to 30 mg in increments of 3 to 7.5 mg. After the development of hypotension, by slow intravenous administration. The usual adult dose is 25 to 50 mg (range 10 to 50 mg) administered intramuscularly or subcutaneously. Additional doses should be based on patient response. The intravenous route may be used if an immediate response is required. The dosage for the intravenous route is
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