Telazol (Tiletamine HCl, NOT RECOMMENDED Zolazepam HCl) General Anesthetics Dose (milligrams per Agent Route Comments kilogram) Alpha Choralose-1% solution 120 IV Use only for “physiological” 80-100 IV preparations; Scientific justification needed Ketamine 20-60 IM Heart rate, respiratory rate, and 15-20 IV blood pressure are depressed; FSH is suppressed (see under tranquilizers) Mixture of Ketamine and Ketamine 60 IM rate, respiratory rate, and Diazepam Diazepam 5-10 blood pressure are depressed; FSH is suppressed (see under tranquilizers) Ketamine and Xylazine 25-50 SC Duration of surgical anesthesia (Rompun) 5-10 minutes) is dose-dependent; analgesia adequate for procedures Pentobarbital 20-50 IV Narrow margin of safety; administer dilute (1-3%) slowly to effect; more concentrated solutions or injections can cause vessel damage and lead to occlusion and necrosis; duration of anesthesia is 30-60 minutes but complete recovery may require 1-10 hours; peak effect of the IP dosage reached in 5-7 minutes; light surgical anesthesia lasts about 120 minutes and complete recovery may take 12-20 hours Isoflurane Induction 2-3% Inhalation Use a non-breathing system; Maintenance 0.25-2% nonflammable and nonexplosive; can be used for euthanasia Analgesics Dose (milligrams per Agent Comments kilogram) Ketoprofen 1.0 IM Every 12-24 hours Buprenorphine 0.1-0.05 IM, SC, or IV Every 6-12 hours Butorphanol 0.1-0.5 SC, IV Every 2-4 hours Morphine 2-5 SC, IM Every 2-4 hours Meloxicam 0.2 PO, SC Every 12-24 hours Miscellaneous
Telazol (Tiletamine HCl, Zolazepam HCl) NOT RECOMMENDED General Anesthetics Agent Dose (milligrams per kilogram) Route Comments Alpha Choralose-1% solution 120 80-100 IV IV Use only for “physiological” preparations; Scientific justification needed Ketamine 20-60 15-20 IM IV Heart rate, respiratory rate, and blood pressure are depressed; FSH is suppressed (see under tranquilizers) Mixture of Ketamine and Diazepam Ketamine 60 Diazepam 5-10 IM rate, respiratory rate, and blood pressure are depressed; FSH is suppressed (see under tranquilizers) Ketamine and Xylazine (Rompun) 25-50 5-10 SC Duration of surgical anesthesia minutes) is dose-dependent; analgesia adequate for procedures Pentobarbital 20-50 IV Narrow margin of safety; administer dilute (1-3%) slowly to effect; more concentrated solutions or injections can cause vessel damage and lead to occlusion and necrosis; duration of anesthesia is 30-60 minutes but complete recovery may require 1-10 hours; peak effect of the IP dosage reached in 5-7 minutes; light surgical anesthesia lasts about 120 minutes and complete recovery may take 12-20 hours Isoflurane Induction 2-3% Maintenance 0.25-2% Inhalation Use a non-breathing system; nonflammable and nonexplosive; can be used for euthanasia Analgesics Agent Dose (milligrams per kilogram) Comments Ketoprofen 1.0 IM Every 12-24 hours Buprenorphine 0.1-0.05 IM, SC, or IV Every 6-12 hours Butorphanol 0.1-0.5 SC, IV Every 2-4 hours Morphine 2-5 SC, IM Every 2-4 hours Meloxicam 0.2 PO, SC Every 12-24 hours Miscellaneous
ARF-standard-operating-procedures.docx