dust/fibre concentrations in the workplace and the longer duration of employment. Estimated risk of asbestosis mortality increased with asbestos cumulative exposure in a convex curve, which tended to be steeper at a low exposure level (<50 fibre/mL-year) than a higher exposure level (>50 fibre/mL-year). Risk of asbestosis mortality rose more sharply than lung cancer mortality at higher exposure levels (>150 fibre/mL-year). Author’s conclusion: study confirmed strong associations between exposure to chrysotile asbestos and lung cancer and asbestosis, in which clear exposure-response relationships were observed. Moolgavkar et Cited by Antao Potency Factors 1662 Libby vermiculite Vermiculite Cumulative Employment Mortality study reporting al (2010) et al (2012) for Risk workers (100% men) mine/mill exposure: N=1662 duration: N=1662 asbestos exposure RMA ID Assessment at M=91.4 M= 3.6 years; producing non-malignant 117=non-malignant 068460 Libby, Montana Worked <1 Worked <1 respiratory disease. Risk respiratory disease year(n=850): 0.27 for non-malignant M=8.5 fibre/mL-year years. Worked respiratory disease ≥1
dust/fibre concentrations in the workplace and the longer duration of employment. Estimated risk of asbestosis mortality increased with asbestos cumulative exposure in a convex curve, which tended to be steeper at a low exposure level (<50 fibre/mL-year) than a higher exposure level (>50 fibre/mL-year). Risk of asbestosis mortality rose more sharply than lung cancer mortality at higher exposure levels (>150 fibre/mL-year). Author’s conclusion: study confirmed strong associations between exposure to chrysotile asbestos and lung cancer and asbestosis, in which clear exposure-response relationships were observed. Moolgavkar et al (2010) Cited by Antao et al (2012) RMA ID 068460 Potency Factors for Risk Assessment at Libby, Montana 1662 Libby vermiculite workers (100% men) 117=non-malignant respiratory disease Vermiculite mine/mill Cumulative exposure: N=1662 M=91.4 Worked <1 M=8.5 fibre/mL-year Employment duration: N=1662 M= 3.6 years; Worked <1 year(n=850): 0.27 years. Worked ≥1 Mortality study reporting asbestos exposure producing non-malignant respiratory disease. Risk for non-malignant respiratory disease
asb_reasons10.12.2015.docx