ESES patients Gender [0=female, 1=male] 0.004 (-0.02 - 0.03) 0.713 versus healthy controls Relative right Intercept 0.59 (0.53 - 0.65) <0.0005 thalamic volume Group [0 ESES patients, 1 refractory epilepsy] 0.03 (0.0001 - 0.06) 0.049 ESES patients Age [years] 0.002 (-0.004 - 0.007) 0.574 versus Gender [0=female, 1=male] -0.01 (-0.04 - 0 .02) 0.386 refractory epilepsy controls Relative right Intercept 0.63 (0.60 - 0.66) <0.0005 Group [0 refractory, 1 healthy control] -0.008 (-0.03- 0.01) 0.436 thalamic volume Refractory Age 0.0003 (-0.003 - 0 .004) 0.836 epilepsy Gender [0=female, 1=male] -0.007 (-0.03- 0.01) 0.450 controls versus healthy controls ANALYSIS OF THE THALAMIC VOLUME AS LEFT+RIGHT THALAMIC VOLUME The volume of the left+right Absolute thalamic volumes (Supplementary Figure 3). thalami was different between the groups (Kruskal-Wallis test, In pairwise p=0.0001). comparisons, left+right thalamic volume was smaller in ESES patients than in healthy controls (medians: 14.99 versus 15.97 cm3, Wilcoxon rank-sum test and in refractory epilepsy p=0.0047), controls than in healthy controls (14.35 versus 15.97 cm3, but was not different p=0.0001), between ESES patients and refractory epilepsy controls (14.67 versus 14.35 cm3, p=0.4181). Absolute volumes of the left + thalami
ESES patients versus healthy controls Gender [0=female, 1=male] 0.004 (-0.02 - 0.03) 0.713 Relative right thalamic volume ESES patients versus refractory epilepsy controls Intercept Group [0 ESES patients, 1 refractory epilepsy] Age [years] Gender [0=female, 1=male] 0.59 (0.53 - 0.65) 0.03 (0.0001 - 0.06) 0.002 (-0.004 - 0.007) -0.01 (-0.04 - 0 .02) <0.0005 0.049 0.574 0.386 Relative right thalamic volume Refractory epilepsy controls versus healthy controls Intercept Group [0 refractory, 1 healthy control] Age Gender [0=female, 1=male] 0.63 (0.60 - 0.66) -0.008 (-0.03- 0.01) 0.0003 (-0.003 - 0 .004) -0.007 (-0.03- 0.01) <0.0005 0.436 0.836 0.450 ANALYSIS OF THE THALAMIC VOLUME AS LEFT+RIGHT THALAMIC VOLUME Absolute thalamic volumes (Supplementary Figure 3). The volume of the left+right thalami was different between the groups (Kruskal-Wallis test, p=0.0001). In pairwise comparisons, left+right thalamic volume was smaller in ESES patients than in healthy controls (medians: 14.99 versus 15.97 cm3, Wilcoxon rank-sum test p=0.0047), and in refractory epilepsy controls than in healthy controls (14.35 versus 15.97 cm3, p=0.0001), but was not different between ESES patients and refractory epilepsy controls (14.67 versus 14.35 cm3, p=0.4181). Absolute volumes of the left + thalami
1-s2.0-S0920121117300505-mmc1.docx