Online Table 3. Treatment-emergent outcomes in the worldwide XANTUS program by region and prior antithrombotic therapy (yes versus no) Outcome All regions Western Europe/ Eastern Europe Middle East/ East Asia Latin America Canada/Israel Africa Yes No Yes No Yes No Yes No Yes No Yes No n=7583 n=3538 n=3789 n=1498 n=1838 n=739 n=389 n=301 n=1426 n=807 n=141 n=193 Major 1.9 1.3 2.4 1.9 1.3 0.6 1.9 1.1 1.6 1.2 0.8 0.6 bleeding All-cause 1.9 1.8 2.0 2.0 1.6 1.1 3.3 1.8 1.7 2.0 3.1 2.3 death 1.0 0.9 1.1 0.8 0.3 0.9 0.8 0.7 2.1 1.4 N/A N/A SE Incidence rates (events/100 patient-years [95% CI]). CI = confidence interval; CNS = central nervous system; N/A = not applicable; SE = systemic embolism.
Online Table 3. Treatment-emergent outcomes in the worldwide XANTUS program by region and prior antithrombotic therapy (yes versus no) Outcome All regions Western Europe/ Canada/Israel Eastern Europe Middle East/ Africa East Asia Latin America Yes n=7583 No n=3538 Yes n=3789 No n=1498 Yes n=1838 No n=739 Yes n=389 No n=301 Yes n=1426 No n=807 Yes n=141 No n=193 Major bleeding 1.9 1.3 2.4 1.9 1.3 0.6 1.9 1.1 1.6 1.2 0.8 0.6 All-cause death 1.9 1.8 2.0 2.0 1.6 1.1 3.3 1.8 1.7 2.0 3.1 2.3 SE 1.0 0.9 1.1 0.8 0.3 0.9 0.8 0.7 2.1 1.4 N/A N/A Incidence rates (events/100 patient-years [95% CI]). CI = confidence interval; CNS = central nervous system; N/A = not applicable; SE = systemic embolism.
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