profusion of examinations the asbestos response relationship according no case of exposure level for 25-99.9 ≥1/1 to American HRCT associated (OR=3.4; 95% Cl: Thoracic asbestosis with each job 0.8, 15.2; p>0.05) Society detected. 60 was assessed and≥100 fibre/mL-year criteriab) participants using (OR=6.1; 95% Cl: 1.5, with <25 published 25.9) in comparison fibre/mL-year, airborne with fibre/mL-year ≤25 Excluded those 2 cases were measurements (Trend test p =0.002) with known detected, both available in but not with duration of having basilar the French exposure (Trend test related diseases crackles and database p=0.791). one having Author’s conclusions: small irregular Aims of study significant association opacities on were to clarify index was between HRCT X-ray group suitable then fibrosis and cumulative for screening by calculated by asbestos exposure, HRCT summing the with a clear values for all response relationship. job positions Only 2 cases of HRCT Variable held, with pulmonary fibrosis asbestos reference to (2%) among the 112 exposure the patients with a although the occupational cumulative fibre main exposure calendar exposure of <25 types unclear established in fibre/mL -years. HRCT the interview, can detect early-stage the products of asbestosis in people Smoking history available the job who have been highly exposure level exposed to asbestos (in fibre/mL) and whose X-ray can by job duration be considered normal. (in years). HRCT screening does not seem warranted Dust for people with low measurements
profusion of ≥1/1 according to American Thoracic Society criteriab) Excluded those with known diseases Aims of study were to clarify group suitable for screening by HRCT Variable asbestos exposure although the main exposure types unclear Smoking history available examinations no case of HRCT asbestosis detected. 60 participants with <25 fibre/mL-year, 2 cases were detected, both having basilar crackles and one having small irregular opacities on X-ray the asbestos exposure level associated with each job was assessed using published airborne measurements available in the French database index was then calculated by summing the values for all job positions held, with reference to the occupational calendar established in the interview, the products of the job exposure level (in fibre/mL) by job duration (in years). Dust measurements relationship for 25-99.9 (OR=3.4; 95% Cl: 0.8, 15.2; p>0.05) and≥100 fibre/mL-year (OR=6.1; 95% Cl: 1.5, 25.9) in comparison with ≤25 fibre/mL-year (Trend test p =0.002) but not with duration of exposure (Trend test p=0.791). Author’s conclusions: significant association between HRCT fibrosis and cumulative asbestos exposure, with a clear relationship. Only 2 cases of HRCT pulmonary fibrosis (2%) among the 112 patients with a cumulative fibre exposure of <25 fibre/mL -years. HRCT can detect early-stage asbestosis in people who have been highly exposed to asbestos and whose X-ray can be considered normal. HRCT screening does not seem warranted for people with low response related response
asb_reasons10.12.2015.docx