GRADEpro Grading of Outcomes Patient or population: Patients with Suspected Tumours Settings: Clinical Intervention: Primary Outcomes Outcomes Illustrative comparative (95% Relative effect No of Quality of the Comments CI) (95% CI) Participants evidence (studies) (GRADE) Assumed risk Corresponding risk Cryotherapy RAPN Recurrence Rates population RR 23.39 767 ⊕⊕⊕⊝ (5.7 to 96.05) (4 studies) moderate1,2,3 115 per 1000 1000 per 1000 (654 to 1000) Moderate 0 per 1000 0 per 1000 (0 to 0) 1101 Overall Study population RR 0.84 ⊕⊕⊝⊝ Complication (0.64 to 1.11) (4 studies) low1,4 140 per 1000 117 per 1000 (89 to 155) Moderate 164 per 1000 138 per 1000 (105 to 182) Clavien 3 or Study population RR 0.71 Higher (0.36 to 1.41) 24 per 1000 17 per 1000 Complications (9 to 34)
GRADEpro Grading of Outcomes Patient or population: Patients with Suspected Tumours Settings: Clinical Intervention: Primary Outcomes Outcomes Illustrative comparative (95% CI) Relative effect (95% CI) No of Participants (studies) Quality of the evidence (GRADE) Comments Assumed risk Corresponding risk Cryotherapy RAPN Recurrence Rates population RR 23.39 (5.7 to 96.05) 767 (4 studies) ⊕⊕⊕⊝ moderate1,2,3 115 per 1000 1000 per 1000 (654 to 1000) Moderate 0 per 1000 0 per 1000 (0 to 0) Overall Complication Study population RR 0.84 (0.64 to 1.11) 1101 (4 studies) ⊕⊕⊝⊝ low1,4 140 per 1000 117 per 1000 (89 to 155) Moderate 164 per 1000 138 per 1000 (105 to 182) Clavien 3 or Higher Complications Study population RR 0.71 (0.36 to 1.41) 24 per 1000 17 per 1000 (9 to 34)
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