Supplementary Table: Details for Patients with Grade 3+ Radiotherapy Related Complications EBRT = external beam radiotherapy. 3D = 3 dimensional. IMRT = intensity modulated radiotherapy. Gy = Gray. D2cc = dose to 2 cubic centimeters. MRI = magnetic resonance imaging. Complication Time from EBRT Dose and Concurrent Brachytherapy Dose Type of Bladder Radiotherapy Type Chemotherapy and Type Surgery D2cc Radiation Cystitis 44 months 3D conformal 45Gy Weekly Cisplatin 5.5Gy x 3 fractions, Open 68.3Gy – Grade 3 in 25 fractions (40mg/m2) 3D Stress Incontinence 31 months IMRT 45Gy in 25 Weekly Cisplatin 5.5Gy x 3 fractions, Open 64.4Gy Grade 3 fractions (40mg/m2) 3D MRI-based – Stress Incontinence 9 months IMRT 45Gy in 25 Weekly Cisplatin 5.5Gy x 4 fractions, Open 73.0Gy Grade 3 fractions (40mg/m2) 3D MRI-based –
Complication Time from Radiotherapy EBRT Dose and Type Concurrent Chemotherapy Brachytherapy Dose and Type Type of Surgery Bladder D2cc Radiation Cystitis – Grade 3 44 months 3D conformal 45Gy in 25 fractions Weekly Cisplatin (40mg/m2) 5.5Gy x 3 fractions, 3D Open 68.3Gy Stress Incontinence – Grade 3 31 months IMRT 45Gy in 25 fractions Weekly Cisplatin (40mg/m2) 5.5Gy x 3 fractions, 3D MRI-based Open 64.4Gy Stress Incontinence – Grade 3 9 months IMRT 45Gy in 25 fractions Weekly Cisplatin (40mg/m2) 5.5Gy x 4 fractions, 3D MRI-based Open 73.0Gy Supplementary Table: Details for Patients with Grade 3+ Radiotherapy Related Complications EBRT = external beam radiotherapy. 3D = 3 dimensional. IMRT = intensity modulated radiotherapy. Gy = Gray. D2cc = dose to 2 cubic centimeters. MRI = magnetic resonance imaging.
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