Vancomycin IV and ceftriaxone (cefotaxime IV in children Coagulase negative staphylococcus Discuss all suspected cases with UHS age <1 month if jaundiced or gestational age <37 weeks) neurosurgeons and local microbiologists. Staph. aureus Uncomplicated 10 days Shunt removal required (CoNS infection may be treated Complicated 21 days (ventriculitis, severe conservatively remove shunt if CSF not sterilised) peritonitis, remaining prosthetic material) – If ventriculitis strongly suspected, add intrathecal Ventriculoperitoneal vancomycin (should be used in conjunction to IV vancomycin) shunt infection
Ventriculoperitoneal shunt infection Coagulase negative staphylococcus Staph. aureus Vancomycin IV and ceftriaxone (cefotaxime IV in children age <1 month if jaundiced or gestational age <37 weeks) Shunt removal required (CoNS infection may be treated conservatively – remove shunt if CSF not sterilised) If ventriculitis strongly suspected, add intrathecal vancomycin (should be used in conjunction to IV vancomycin) Discuss all suspected cases with UHS neurosurgeons and local microbiologists. Uncomplicated 10 days Complicated 21 days (ventriculitis, severe peritonitis, remaining prosthetic material)
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