3.95 3.67 3.76 4.00 3.74 4.20 3.98 4.19 5.15 3.73 4.23 3.88 3H -OCH3-10 3.9 4.06 3.28 4.08 4.21 4.06 3.87 3.85 4.18 3.74 2.00 1.77 2.07 1.76 3H - C14 1.86 1.99 1.46 2.01 1.68 1.65 1.89 1.65 1.99 2.00 1H - NH 7.4 7.55 5.37 5.10 6.19 5.50 Table S10. 13C NMR calculated isotropic values for colchicine and its complexes (M06/pcS-2). Isotropic values Calculated Atom C 1 1:1:1 Type D 1:1:1 Type E 1:1:1 Type F 7.89 4.00 8.82 C1 2.87 37.72 32.49 39.59 42.44 C1a 18.85 23.71 19.79 26.85 C2 2.42 1.30 -0.10 7.59 C3 58.93 50.71 58.46 54.86 C4 15.78 16.66 16.19 10.44 C4a 143.02 143.92 142.37 143.23 C5 138.49 134.07 138.05 139.90 C6 110.61 102.67 114.62 112.38 C7 10.21 16.52 -5.48 12.11 C7a 17.05 21.52 17.24 23.90 C8 -24.83 -24.02 -13.14 -30.06 C9 -7.90 -9.23 -0.21 -7.08 C10 43.15 52.36 43.13 54.40 C11
3.95 3.67 3.76 4.00 3.74 4.20 3.98 4.19 3H -OCH3-10 3.9 4.06 5.15 3.73 4.23 3.88 3.28 4.08 4.21 4.06 3.87 3.85 4.18 3.74 3H - C14 1.86 1.99 2.00 1.77 2.07 1.76 1.46 2.01 1.68 1.65 1.89 1.65 1.99 2.00 1H - NH 7.4 7.55 5.37 5.10 6.19 5.50 Table S10. 13C NMR calculated isotropic values for colchicine and its complexes (M06/pcS-2). Isotropic values Atom C Calculated 1 1:1:1 Type D 1:1:1 Type E 1:1:1 Type F C1 2.87 7.89 4.00 8.82 C1a 37.72 32.49 39.59 42.44 C2 18.85 23.71 19.79 26.85 C3 2.42 1.30 -0.10 7.59 C4 58.93 50.71 58.46 54.86 C4a 15.78 16.66 16.19 10.44 C5 143.02 143.92 142.37 143.23 C6 138.49 134.07 138.05 139.90 C7 110.61 102.67 114.62 112.38 C7a 10.21 16.52 -5.48 12.11 C8 17.05 21.52 17.24 23.90 C9 -24.83 -24.02 -13.14 -30.06 C10 -7.90 -9.23 -0.21 -7.08 C11 43.15 52.36 43.13 54.40
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