ANALGESICS - Analgesics to be used intra- and post-operatively Species Agent Dose Route Frequency & Duration Initial dose given at induction of anaesthesia then e.g. Mouse buprenorphine 0.05-0.1mg/kg Sub cut continued every 8 hours for 3 days post-op Which investigator/s as detailed in the application will perform these procedures? 17. ANIMAL WELL-BEING Animal Monitoring - Monitoring sheets have recently been updated to respond to the most recent edition of the animal code, current best practice and AEC requirement. Please ensure you use the latest monitoring templates to avoid delays in processing your application. See Monitoring Training Video - E- mail: to receive an autoreply with a link to the Monitoring Training Video which you can view while drafting the monitoring sheets It provides step-by-step instructions on how to use the templates to – create monitoring sheets tailored to your project Animal Monitoring - Attach appropriate Cover Sheet and Recording Sheet for project monitoring. Attached [ ] In some exceptional circumstances, formal monitoring documents may not be necessary but you must provide an explanation and justification in this box. If you are unsure, contact Estimated morbidity and mortality (death/euthanasia) rates (%) - List any likely condition or complication that would result in impaired health, death or euthanasia of animals prior to the defined experimental study endpoints. State maximum morbidity and mortality rate (%) of each possible cause in the table below. % Potential cause impact on steps taken to minimise % mortality wellbeing impact morbidIty % of animal death % of animals or intervention affected euthanasia Malaise / inappetant 10% 1% e.g. elevated body Soft food on cage floor (i.e. 10% of all the (i.e. 1% of all the temperature animals on the project) animals on the project) e.g. vessel rupture irreversible Haemorrhage apparent to 5% 5% haemorrhage surgeon, animal would be euthanased whilst still under general anaesthesia. Total mortality Total morbidity rate (%) rate (%) State estimated maximum for the whole project. PLease note that all adverse events must be promptly reported to facility staff and the Awo. 18. COMPLETION OF EXPERIMENT – Fate of the animals at the end of the experiment.
ANALGESICS - Analgesics to be used intra- and post-operatively Species Agent Dose Route Frequency & Duration e.g. Mouse buprenorphine 0.05-0.1mg/kg Sub cut Initial dose given at induction of anaesthesia then continued every 8 hours for 3 days post-op Which investigator/s as detailed in the application will perform these procedures? 17. ANIMAL WELL-BEING Animal Monitoring - Monitoring sheets have recently been updated to respond to the most recent edition of the animal code, current best practice and AEC requirement. Please ensure you use the latest monitoring templates to avoid delays in processing your application. See Monitoring Training Video - E- mail: to receive an autoreply with a link to the Monitoring Training Video which you can view while drafting the monitoring sheets – It provides step-by-step instructions on how to use the templates to create monitoring sheets tailored to your project Animal Monitoring - Attach appropriate Cover Sheet and Recording Sheet for project monitoring. Attached [ ] In some exceptional circumstances, formal monitoring documents may not be necessary but you must provide an explanation and justification in this box. If you are unsure, contact Estimated morbidity and mortality (death/euthanasia) rates (%) - List any likely condition or complication that would result in impaired health, death or euthanasia of animals prior to the defined experimental study endpoints. State maximum morbidity and mortality rate (%) of each possible cause in the table below. Potential cause impact on wellbeing steps taken to minimise impact % morbidIty % of animals affected % mortality % of animal death or intervention euthanasia e.g. elevated body temperature Malaise / inappetant Soft food on cage floor 10% (i.e. 10% of all the animals on the project) 1% (i.e. 1% of all the animals on the project) e.g. vessel rupture irreversible haemorrhage Haemorrhage apparent to surgeon, animal would be euthanased whilst still under general anaesthesia. 5% 5% State estimated maximum for the whole project. Total morbidity rate (%) Total mortality rate (%) PLease note that all adverse events must be promptly reported to facility staff and the Awo. 18. COMPLETION OF EXPERIMENT – Fate of the animals at the end of the experiment.
AEC-Application-RESEARCH.docx