Presenting signs (probable and possible) Injection site reaction (1) Oedema (1) Lack of effect (1) Pain (1) Ovine Number of Reports Probable Possible 3 3 0 Presenting signs (probable and possible) Injection site reaction (2) Ataxia (1) Shaking (1) Abscess (1) Death (1) Cyclosporin Cyclosporin is a widely used immunosuppressant drug used in the treatment of immune-mediated conditions. The most commonly reported presenting signs are gastrointestinal related, most notably vomiting and diarrhoea. The number of reports associated with Cyclosporin is low when compared with the number of doses sold in 2013 (less than 1 in 10 000 doses) and therefore no regulatory action is required other than continued monitoring for unexpected or severe reactions. Cyclosporin Canine Number of Reports Probable Possible 87 56 31 Presenting signs (probable and possible) Vomiting (55) Tremor (3) Vocalisation (2) Diarrhoea (21) Behavioural change (2) Abdominal pain (1) Pruritis (16) Coat colour change (2) Agitation (1) Lethargy (9) Eczema (2) Alopecia (1) Anorexia (8) Erythema (2) Cellulitis (1) Tachypnoea (6) Hyperkeratosis (2) Collapse (1) Distress (4) Injected mucous membranes (2) Dehydration (1) Hyperactivity (4) Neoplasia (2) Diabetes (1) Dermatitis (3) Red eyes (2) Elevated ALP (1)
Presenting signs (probable and possible) Injection site reaction (1) Lack of effect (1) Oedema (1) Pain (1) Ovine Number of Reports Probable Possible 3 3 0 Presenting signs (probable and possible) Injection site reaction (2) Abscess (1) Ataxia (1) Death (1) Shaking (1) Cyclosporin Cyclosporin is a widely used immunosuppressant drug used in the treatment of immune-mediated conditions. The most commonly reported presenting signs are gastrointestinal related, most notably vomiting and diarrhoea. The number of reports associated with Cyclosporin is low when compared with the number of doses sold in 2013 (less than 1 in 10 000 doses) and therefore no regulatory action is required other than continued monitoring for unexpected or severe reactions. Cyclosporin Canine Number of Reports Probable Possible 87 56 31 Presenting signs (probable and possible) Vomiting (55) Diarrhoea (21) Pruritis (16) Lethargy (9) Anorexia (8) Tachypnoea (6) Distress (4) Hyperactivity (4) Dermatitis (3) Tremor (3) Behavioural change (2) Coat colour change (2) Eczema (2) Erythema (2) Hyperkeratosis (2) Injected mucous membranes (2) Neoplasia (2) Red eyes (2) Vocalisation (2) Abdominal pain (1) Agitation (1) Alopecia (1) Cellulitis (1) Collapse (1) Dehydration (1) Diabetes (1) Elevated ALP (1)
adverse-experiences-for-veterinary-medicines-and-agricultural-chemicals-2013.docx