>28 days-18yr: 60mg/kg IV 8-hourly (max dose 1g every 8 hours) Enterococcal endocarditis: <7days: 60mg/kg 12-hourly 7- 28days: 60mg/kg 8-hourly. >28 days-18yr: 60mg/kg 4–6 hourly (max 2g 4- hourly). Treatment: All ages: test dose 100micrograms/kg (max 1mg) over 15mins, observe for 30mins. If no reaction Amphotericin follow 1 hr later by 3mg/kg once daily (Ambisome®) Prophylaxis: 1mg/kg once daily on Mon, Wed, Fri
>28 days-18yr: 60mg/kg IV 8-hourly (max dose 1g every 8 hours) Enterococcal endocarditis: <7days: 60mg/kg 12-hourly 7- 28days: 60mg/kg 8-hourly. >28 days-18yr: 60mg/kg 4–6 hourly (max 2g 4- hourly). Amphotericin (Ambisome®) Treatment: All ages: test dose 100micrograms/kg (max 1mg) over 15mins, observe for 30mins. If no reaction follow 1 hr later by 3mg/kg once daily Prophylaxis: 1mg/kg once daily on Mon, Wed, Fri
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