Isomerases Isomerases convert their substrates to their isomers by intramolecular rearrangement They are divided into subclasses according to the type of isomerization Examples: 5.1.1.1 Alanine raecimase 5.3.1.9 Glucose 6-phosphate isomerase (or) phosphohexose isomerase 5.4.2.1 Phosphoglycerate mutase Ligases Ligases are enzymes that catalyze the formation of a bond between 2 substrates They catalyze the formation of bonds between C, O, N, and S coupled to hydrolysis of high energy compounds like ATP They catalyze reactions of the type: or They are subdivided into classes according to the atom connected by the new bond Examples: 6.1.1.1 Tyrosine t-RNA ligase 6.1.1.2 Tryptophan t-RNA ligase 6.1.1.3 Threonine t-RNA ligase
Isomerases Isomerases convert their substrates to their isomers by intramolecular rearrangement They are divided into subclasses according to the type of isomerization Examples: 5.1.1.1 Alanine raecimase 5.3.1.9 Glucose 6-phosphate isomerase (or) phosphohexose isomerase 5.4.2.1 Phosphoglycerate mutase Ligases Ligases are enzymes that catalyze the formation of a bond between 2 substrates They catalyze the formation of bonds between C, O, N, and S coupled to hydrolysis of high energy compounds like ATP They catalyze reactions of the type: or They are subdivided into classes according to the atom connected by the new bond Examples: 6.1.1.1 Tyrosine t-RNA ligase 6.1.1.2 Tryptophan t-RNA ligase 6.1.1.3 Threonine t-RNA ligase
33720603-Introduction-to-Enzymes.docx