Headache Photophobia Nuchal Rigidy Opisthotonic position sign Positive Kernig’s sign Postive Brudzinski’s Diagnostic Tests Lumbar Puncture Serum Glucose Level Blood Cultures Syndrome Down’s Trisomy 21- the most common chromosomal abnormality resulting in mild to profound intellectual Disability Down syndrome Clinical Manifestations: Congenital anomalies cardiac and GI tract – Flat facial features, nose broad and flat Low set ears Upward slanting eyes Prominent epicanthial folds Short hands with simian crease Hypotonia Neck short with extra fat pad Usually sterile
Headache Photophobia Nuchal Rigidy Opisthotonic position Positive Kernig’s sign Postive Brudzinski’s sign Diagnostic Tests Lumbar Puncture Serum Glucose Level Blood Cultures Down’s Syndrome Trisomy 21- the most common chromosomal abnormality resulting in mild to profound intellectual Disability Down syndrome Clinical Manifestations: Congenital anomalies – cardiac and GI tract Flat facial features, nose broad and flat Low set ears Upward slanting eyes Prominent epicanthial folds Short hands with simian crease Hypotonia Neck short with extra fat pad Usually sterile
20c._pediatric_neurology_disorders.docx