In a accompanying the new study, published by , Dr. David Sinclair describes the compound NMN boosts levels of NAD in the bodies of aging mice, and how that restores muscle function. Vascular aging leads to a deterioration in many organs and tissues throughout the human body, as Dr. David Sinclair says: “As we age, the tiniest blood vessels in our bodies wither and die, reducing the blood flow to organs and tissues. Vascular aging causes many diseases — cardiovascular, neurological, muscle wasting, frailty, and even aging. Here at Harvard Medical School, we’ve reversed the process in mice, setting the stage for radical new therapies to help people. The new study has unraveled the cascade of interactions between blood vessels and muscles. “ NMN Boosts NAD in aging endothelial cells. Source: Harvard Medical School (HMS) (video). Dr. David Sinclair also describes the how aging of the cells lining our blood vessels leads to a decline in our vascular systems and muscles, saying: “Endothelial cells, which line the walls of blood vessels, are essential for the health and growth of the vessels. And as endothelial cells age, blood vessels begin to atrophy and die. Blood flow to many parts of the body diminishes, organs and tissues begin to function less well. Blood vessel demise hits muscles especially hard because muscles rely on a robust blood supply for their function. This process can be slowed down with regular exercise, but only up to a point. Over time, even exercise fails to stave off blood vessel demise and muscle loss. “ The decline in NAD causes aging blood vessels and loss of muscle tissue says Dr. David Sinclair. Credit: Lewis Lipsitz via HMS.
In a accompanying the new study, published by , Dr. David Sinclair describes the compound NMN boosts levels of NAD in the bodies of aging mice, and how that restores muscle function. Vascular aging leads to a deterioration in many organs and tissues throughout the human body, as Dr. David Sinclair says: “As we age, the tiniest blood vessels in our bodies wither and die, reducing the blood flow to organs and tissues. Vascular aging causes many diseases — cardiovascular, neurological, muscle wasting, frailty, and even aging. Here at Harvard Medical School, we’ve reversed the process in mice, setting the stage for radical new therapies to help people. The new study has unraveled the cascade of interactions between blood vessels and muscles. “ NMN Boosts NAD in aging endothelial cells. Source: Harvard Medical School (HMS) (video). Dr. David Sinclair also describes the how aging of the cells lining our blood vessels leads to a decline in our vascular systems and muscles, saying: “Endothelial cells, which line the walls of blood vessels, are essential for the health and growth of the vessels. And as endothelial cells age, blood vessels begin to atrophy and die. Blood flow to many parts of the body diminishes, organs and tissues begin to function less well. Blood vessel demise hits muscles especially hard because muscles rely on a robust blood supply for their function. This process can be slowed down with regular exercise, but only up to a point. Over time, even exercise fails to stave off blood vessel demise and muscle loss. “ The decline in NAD causes aging blood vessels and loss of muscle tissue says Dr. David Sinclair. Credit: Lewis Lipsitz via HMS.
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