Computational Bioengineering and Biophysics Our research in the biomedical engineer- ing area includes a variety of different fields. In all of them we collaborate with experts from medicine, biology or biophy- sics. Some activities are the development of a comprehensive coupled multiscale model of the respiratory system, of a model for rupture risk prediction of abdominal aortic aneurysms, compre- hensive cardiac modeling, simulation of surgical procedures or cellular modeling. In recent years we have also successfully entered the area of biophysics, where we Verification of a beating heart simulation with MRI images a novel, theoretically sound and highly efficient approach for the Brownian dynamics of polymers. Based on this unique approach we meanwhile could study and answer a number of open Experimental testing of viable precision cut lung slices with computational identification of constitutive questions in the biophysics community. relationship Vascular Growth and Remodeling in Aneurysms (Emmy-Noether Group headed by Dr. C. Cyron) aims at exploring the biomechanical and supporting only eight Aneurysms are focal dilatations of blood groups in the area of vessels that often grow over years and mechanics and design. finally rupture. Rupturing aneurysms are biochemical mechanisms governing the among the leading causes of mortality growth of aneurysms, with the perspective and morbidity in industrialized countries. of exploiting these for the development While over the last decades our general of future therapies and computer-aided understanding of the biomechanics of diagnosis. To this end, the Emmy-Noether aneurysms has advanced substantially, group will combine advanced methods the factors governing their growth – from computational mechanics with state- although key to develop future therapies of-the-art medical imaging technology remain poorly understood. In February – and machine learning. The Emmy-Noether Computer simulation of the blood 2015, Dr. Christian Cyron established the program of the German Research Foun- flow in the circle of Willis in a Emmy-Noether group for vascular growth dation (DFG) was established in 1999 to patient with cerebral aneurysm and remodeling in aneurysms at the support groundbreaking projects of young Institute for Computational Mechanics. It researchers. Since then the DFG has been
Computational Bioengineering and Biophysics Our research in the biomedical engineer- ing area includes a variety of different fields. In all of them we collaborate with experts from medicine, biology or biophy- sics. Some activities are the development of a comprehensive coupled multiscale model of the respiratory system, of a model for rupture risk prediction of abdominal aortic aneurysms, compre- hensive cardiac modeling, simulation of surgical procedures or cellular modeling. In recent years we have also successfully entered the area of biophysics, where we Verification of a beating heart simulation with MRI images Experimental testing of viable precision cut lung slices with computational identification of constitutive relationship a novel, theoretically sound and highly efficient approach for the Brownian dynamics of polymers. Based on this unique approach we meanwhile could study and answer a number of open questions in the biophysics community. Vascular Growth and Remodeling in Aneurysms (Emmy-Noether Group headed by Dr. C. Cyron) Aneurysms are focal dilatations of blood vessels that often grow over years and finally rupture. Rupturing aneurysms are among the leading causes of mortality and morbidity in industrialized countries. While over the last decades our general understanding of the biomechanics of aneurysms has advanced substantially, the factors governing their growth – although key to develop future therapies – remain poorly understood. In February 2015, Dr. Christian Cyron established the Emmy-Noether group for vascular growth and remodeling in aneurysms at the Institute for Computational Mechanics. It aims at exploring the biomechanical and biochemical mechanisms governing the growth of aneurysms, with the perspective of exploiting these for the development of future therapies and computer-aided diagnosis. To this end, the Emmy-Noether group will combine advanced methods from computational mechanics with state- of-the-art medical imaging technology and machine learning. The Emmy-Noether program of the German Research Foun- dation (DFG) was established in 1999 to support groundbreaking projects of young researchers. Since then the DFG has been supporting only eight groups in the area of mechanics and design. Computer simulation of the blood flow in the circle of Willis in a patient with cerebral aneurysm
41-Wall-Institute_of_Computational_Mechanics_2015.docx