Gastroenterology Clinical features and HLA association of 5-Aminosalicylate (5-ASA) induced nephrotoxicity in inflammatory bowel disease Authors Graham A Heap Ian Lawrance Kenji So Charlie Lees Mike Weedon Steve Lewis Naomi Ebney Melanie Lockett Claire Bewshea Stephen Mann Abhey Singh John Mansfield Vito Annesse Craig Mowat John Beckly Chris Mulgrew Dorien Buurman Frank Muller Rakesh Chaudhary Charles Murray Andrew T Cole Richard Oram Sheldon Cooper Tim Orchard Tom Creed Miles Parkes Fraser Cummings Rosemary Phillips Nanne KH D'Boer Richard Pollok Renata D'Inca Graham Radford-Smith Richard D'Souza Shaji Sebastian Tawfique K Daneshmend Sandip Sen Michael Delaney Asheesh Sharma Anjan Dhar Tariq Shirazi Natalie Direkze Mark Silverberg Paul Dunckley Laurie Solomon Daniel Gaya Giacomo C Sturniolo Richard Gearry Mark Thomas Steve Gore Mark Tremelling Jonas Halfvarson Epameinondas V Tsianos Ailsa Hart David Watts Chris J Hawkey Sean Weaver Frank Hoentjen Rinse Weersma Tariq Iqbal Emma Wesley Peter Irving Arthur Holden Simon Lal Tariq Ahmad Author contribution statement TA and A.Holden conceived the study. GAH, KS, NE, AS, TA collated submitted cases. CB project managed the study. GAH, KS, NE, AS, TA, TKD, A.Hart, IL, S.Lewis, C.Mulgrew, RD’S, RO, TS, EW performed adjudication of submitted cases. GAH performed clinical data analysis. GAH and MW performed genetic analysis. VA, JB, DB, RC, ATC, SC, TC, FC, NKHD, RD’I, TKD, MD, AD, ND, PD, DG, RG, SG, JH, A.Hart, CJH, FH, TI, PI, S.Lal, IL, CL, SL, ML, SM, JM, C.Mowat, FM, CM, TO, MP, R.Phillips, R.Pollock, GRS, S.Sebastian, S.Sen, A.Sharma, MS, LS, GCS, M.Thomas, M.Tremelling, ET, DW, SW, RW submitted a
Gastroenterology Clinical features and HLA association of 5-Aminosalicylate (5-ASA) induced nephrotoxicity in inflammatory bowel disease Authors Graham A Heap Kenji So Mike Weedon Naomi Ebney Claire Bewshea Abhey Singh Vito Annesse John Beckly Dorien Buurman Rakesh Chaudhary Andrew T Cole Sheldon Cooper Tom Creed Fraser Cummings Nanne KH D'Boer Renata D'Inca Richard D'Souza Tawfique K Daneshmend Michael Delaney Anjan Dhar Natalie Direkze Paul Dunckley Daniel Gaya Richard Gearry Steve Gore Jonas Halfvarson Ailsa Hart Chris J Hawkey Frank Hoentjen Tariq Iqbal Peter Irving Simon Lal Ian Lawrance Charlie Lees Steve Lewis Melanie Lockett Stephen Mann John Mansfield Craig Mowat Chris Mulgrew Frank Muller Charles Murray Richard Oram Tim Orchard Miles Parkes Rosemary Phillips Richard Pollok Graham Radford-Smith Shaji Sebastian Sandip Sen Asheesh Sharma Tariq Shirazi Mark Silverberg Laurie Solomon Giacomo C Sturniolo Mark Thomas Mark Tremelling Epameinondas V Tsianos David Watts Sean Weaver Rinse Weersma Emma Wesley Arthur Holden Tariq Ahmad Author contribution statement TA and A.Holden conceived the study. GAH, KS, NE, AS, TA collated submitted cases. CB project managed the study. GAH, KS, NE, AS, TA, TKD, A.Hart, IL, S.Lewis, C.Mulgrew, RD’S, RO, TS, EW performed adjudication of submitted cases. GAH performed clinical data analysis. GAH and MW performed genetic analysis. VA, JB, DB, RC, ATC, SC, TC, FC, NKHD, RD’I, TKD, MD, AD, ND, PD, DG, RG, SG, JH, A.Hart, CJH, FH, TI, PI, S.Lal, IL, CL, SL, ML, SM, JM, C.Mowat, FM, CM, TO, MP, R.Phillips, R.Pollock, GRS, S.Sebastian, S.Sen, A.Sharma, MS, LS, GCS, M.Thomas, M.Tremelling, ET, DW, SW, RW submitted a
5ASA_Nephrotoxocity_version_5.docx