For some years, the Australian Department of the Environment has been applying a hazard classification system for bee toxicity based on that described in Mensink et al (1995). The three highest hazard classifications in this scheme are: LD50 <0.1 µg/bee Highly toxic LD50 0.1–1.0 µg/bee Toxic LD50 1.0–10 µg/bee Moderately toxic It is appropriate to maintain the rating system that has been used historically in Australia; these classifications are applied to invoke the following hazard statements on the label: Hazard-based label statements Table 11: Hazard statements based on adult acute oral and contact toxicity results >10 µg/bee No statement required 1.0–10 µg/bee Moderately toxic to bees 0.1–1.0 µg/bee Toxic to bees <0.1 µg/bee Highly toxic to bees Systemic compounds: Apiarists requested the APVMA to include information on product labels if the active constituent has a systemic mode of action. The following statement is suggested. Table 12: Statement for active constituents which have a systemic action SUGGESTED Systemic compounds <ACTIVE> has a systemic action. Risk-based label statements Even though a substance may be hazardous its use may be acceptable if exposure is unlikely to result in levels which are toxic to the organism. The following statements are designed to communicate the potential for risk to bees. Where a hazard statement is required, these risk-based statements should follow the hazard statement: Table 13: Risk statements based on risk quotients (RQs) SUGGESTED Hazardous, but RQ <LOC The use pattern as per the Directions for Use is not expected to result in exposure to bees.
For some years, the Australian Department of the Environment has been applying a hazard classification system for bee toxicity based on that described in Mensink et al (1995). The three highest hazard classifications in this scheme are: LD50 <0.1 µg/bee Highly toxic LD50 0.1–1.0 µg/bee Toxic LD50 1.0–10 µg/bee Moderately toxic It is appropriate to maintain the rating system that has been used historically in Australia; these classifications are applied to invoke the following hazard statements on the label: Hazard-based label statements Table 11: Hazard statements based on adult acute oral and contact toxicity results >10 µg/bee No statement required 1.0–10 µg/bee Moderately toxic to bees 0.1–1.0 µg/bee Toxic to bees <0.1 µg/bee Highly toxic to bees Systemic compounds: Apiarists requested the APVMA to include information on product labels if the active constituent has a systemic mode of action. The following statement is suggested. Table 12: Statement for active constituents which have a systemic action SUGGESTED Systemic compounds <ACTIVE> has a systemic action. Risk-based label statements Even though a substance may be hazardous its use may be acceptable if exposure is unlikely to result in levels which are toxic to the organism. The following statements are designed to communicate the potential for risk to bees. Where a hazard statement is required, these risk-based statements should follow the hazard statement: Table 13: Risk statements based on risk quotients (RQs) Hazardous, but RQ <LOC The use pattern as per the Directions for Use is not expected to result in exposure to bees. SUGGESTED
27551-27551-1_apvma_ra_road_map_-_final-october_2017_a656939_2.docx