Table 2. Results of multivariate regressions for the full DRIE dataset (in 188 participants). Type of Linear regression on serum Logistic regression on Logistic regression on current indicator osmolality* impending dehydration (90 dehydration (38 people have current people have impending or dehydration) current dehydration) Measure Coefficient (95% CI), Measure Odds ratio (95% Measure Odds (95% CI), p-value CI), p-value p-value Renal eGFR -0.09 (-0.15 to -0.03) eGFR 0.98 (0.96 to 0.99) eGFR 0.98 (0.95 to 1.00) function p=0.005 p=0.007 p=0.045 Cognitive MMSE score -0.37 (-0.56 to -0.18) MMSE 0.93 (0.88 to 0.98) MMSE drawing 0.26 (0.11 to 0.65) p<0.001 score p=0.010 sub-score p=0.004 function Diabetic Uses diabetic 6.72 (3.39 to 10.04) Diabetic 3.77 (1.59 to 8.93) Use of any 6.77 (2.18 to 21.04) status medication p<0.001 status p=0.003 diabetic p=0.001 medication Other factors -4.93 (-9.09 to -0.77) sex 2.00 (1.01 to 3.97) Healthcare 1.07 (1.01 to 1.13) p=0.021 p=0.047 contacts in past p=0.027 diuretic 2 months *Serum osmolality = 306.0 (0.086*eGFR) (0.37 *MMSE) + 6.72 if uses diabetic medication 4.93 if uses potassium-sparing – – – diuretics
Table 2. Results of multivariate regressions for the full DRIE dataset (in 188 participants). Type of indicator Linear regression on serum osmolality* Logistic regression on impending dehydration (90 people have impending or current dehydration) Logistic regression on current dehydration (38 people have current dehydration) Measure Coefficient (95% CI), p-value Measure Odds ratio (95% CI), p-value Measure Odds (95% CI), p-value Renal function eGFR -0.09 (-0.15 to -0.03) p=0.005 eGFR 0.98 (0.96 to 0.99) p=0.007 eGFR 0.98 (0.95 to 1.00) p=0.045 Cognitive function MMSE score -0.37 (-0.56 to -0.18) p<0.001 MMSE score 0.93 (0.88 to 0.98) p=0.010 MMSE drawing sub-score 0.26 (0.11 to 0.65) p=0.004 Diabetic status Uses diabetic medication 6.72 (3.39 to 10.04) p<0.001 Diabetic status 3.77 (1.59 to 8.93) p=0.003 Use of any diabetic medication 6.77 (2.18 to 21.04) p=0.001 Other factors diuretic -4.93 (-9.09 to -0.77) p=0.021 sex 2.00 (1.01 to 3.97) p=0.047 Healthcare contacts in past 2 months 1.07 (1.01 to 1.13) p=0.027 *Serum osmolality = 306.0 – (0.086*eGFR) – (0.37 *MMSE) + 6.72 if uses diabetic medication – 4.93 if uses potassium-sparing diuretics
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