vitamin D supplements Age, alcohol consumption, aspirin use, BMI, family history of colorectal cancer in first degree WHS, relatives, history Distribution of Self-report, Prospective of polyps, person-years by report, national Zhang, 2006 Cohort, 220/ menopausal exposure death Index, Incidence, vs ≥385 ≤243 COL40742 Age: 45- years, 37 916 131-item FFQ 0.67 (0.43-1.03) status, physical category. medical records colorectal cancer mcg/day USA W, 10.1 years activity, of reviewed by Health postmenopausal exposure physicians professionals hormone use, categories. randomized treatment assignment, red meat intake, smoking status, total energy intake Distribution of China, Haining Non-cases. Age, sex, City of Zhejiang Mid-points of vs alcohol intake, ≥172.08 Jiang, 2005 Province, 73/ exposure Incidence, rectal methionine ≤115.63 COL01846 Nested Case Cancer registry FFQ 343 controls 1.39 (0.56-3.50) categories. cancer mcg/1000 intake, smoking Control, 12 intakes in kcal/day habits, zinc Age: 40- years, intake M/W converted to mcg/day using
vitamin D supplements Zhang, 2006 COL40742 USA WHS, Prospective Cohort, Age: 45- years, W, Health professionals 220/ 37 916 10.1 years Self-report, report, national death Index, medical records reviewed by physicians 131-item FFQ Incidence, colorectal cancer ≥385 vs ≤243 mcg/day 0.67 (0.43-1.03) Age, alcohol consumption, aspirin use, BMI, family history of colorectal cancer in first degree relatives, history of polyps, menopausal status, physical activity, postmenopausal hormone use, randomized treatment assignment, red meat intake, smoking status, total energy intake Distribution of person-years by exposure category. of exposure categories. Jiang, 2005 COL01846 China, Haining City of Zhejiang Province, Nested Case Control, Age: 40- years, M/W 73/ 343 controls 12 Cancer registry FFQ Incidence, rectal cancer ≥172.08 vs ≤115.63 mcg/1000 kcal/day 1.39 (0.56-3.50) Age, sex, alcohol intake, methionine intake, smoking habits, zinc intake Distribution of Non-cases. Mid-points of exposure categories. intakes in converted to mcg/day using
CUP_colorectal_SLR_2016_RO.docx