Age, alcohol, diabetes, educational WHI, Self-report level, energy, Prospective verified by ethnicity, family 2013 Cohort, 166/ reviewing history of Incidence, 1.18 (0.74-1.90) Mid-point COL40965 Age: 50-79 11 124 medical and Measured vs colorectal ≥0.85 ≤0.75 colorectal cancer Ptrend:0.40 categories USA years, 12.9 years pathological cancer, HRT W, records by use, pack yrs of Postmenopausal physicians smoking, physical activity, randomisation Age, age at menopause, estrogen use, alcohol, physical IWHS, activity, Oxentenko, Prospective 1 464/ smoking status 2010 Cohort, 36 941 Incidence, 1.28 (1.08-1.50) and intensity, Mid-point SEER Self-reported vs ≥0.9 ≤0.78 COL40849 Age: 55-69 619 961 colorectal cancer Ptrend:0.003 diabetes, energy categories USA years, intake, intakes W of folate, fruits and vegetables, red meat, total fat, vitamin E,calcium EPIC, Incidence, 1.51 (1.06 to Pischon, 2006 Population 416/ 0.990 vs < ≥ Prospective Measured colon, 2.15) COL01985 registries 368 277 0.887 Cohort, men Ptrend:0.006 6.1 years
2013 COL40965 USA WHI, Prospective Cohort, Age: 50-79 years, W, Postmenopausal 166/ 11 124 12.9 years Self-report verified by reviewing medical and pathological records by physicians Measured Incidence, colorectal cancer ≥0.85 vs ≤0.75 1.18 (0.74-1.90) Ptrend:0.40 Age, alcohol, diabetes, educational level, energy, ethnicity, family history of colorectal cancer, HRT use, pack yrs of smoking, physical activity, randomisation Mid-point categories Oxentenko, 2010 COL40849 USA IWHS, Prospective Cohort, Age: 55-69 years, W 1 464/ 36 941 619 961 SEER Self-reported Incidence, colorectal cancer ≥0.9 vs ≤0.78 1.28 (1.08-1.50) Ptrend:0.003 Age, age at menopause, estrogen use, alcohol, physical activity, smoking status and intensity, diabetes, energy intake, intakes of folate, fruits and vegetables, red meat, total fat, vitamin E,calcium Mid-point categories Pischon, 2006 COL01985 EPIC, Prospective Cohort, 416/ 368 277 6.1 years Population registries Measured Incidence, colon, men ≥ 0.990 vs < 0.887 1.51 (1.06 to 2.15) Ptrend:0.006
CUP_colorectal_SLR_2016_RO.docx