Table 121 Cheese intake and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response analysis Cases/ Author, Year, name, Study size Case Exposure Adjustment Missing data derived for WCRF Code, Outcome Comparison RR (95%CI) characteristics Follow-up ascertainment assessment factors analysis Country (years) Incidence, vs 0-4.9 0.87 ≥56 colorectal g/d cancer Incidence, 0.95 colorectal per 50 g/day cancer Incidence, vs 0-4.9 0.83 ≥56 colon cancer g/d Incidence, 0.93 Murphy, 2013 Cancer per 50 g/day colon cancer COL41070 registries, EPIC, health Incidence, Prospective 4 513/ vs 0-4.9 0.73 ≥56 Insurance Dietary proximal Cohort, 477 122 g/d records, questionnaire cancer Age: 30- years, 11 years pathology rec M/W Incidence, & active follow 0.95 proximal per 50 g/day up cancer Incidence, vs 0-4.9 0.91 ≥56 distal colon g/d cancer Incidence, 0.94 distal per 50 g/day cancer Incidence, vs 0-4.9 0.95 ≥56 rectal cancer g/d
Table 121 Cheese intake and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response Author, Year, WCRF Code, Country name, characteristics Cases/ Study size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Adjustment factors Missing data derived for analysis Murphy, 2013 COL41070 EPIC, Prospective Cohort, Age: 30- years, M/W 4 513/ 477 122 11 years Cancer registries, health Insurance records, pathology rec & active follow up Dietary questionnaire Incidence, colorectal cancer ≥56 vs 0-4.9 g/d 0.87 Incidence, colorectal cancer per 50 g/day 0.95 Incidence, colon cancer ≥56 vs 0-4.9 g/d 0.83 Incidence, colon cancer per 50 g/day 0.93 Incidence, proximal cancer ≥56 vs 0-4.9 g/d 0.73 Incidence, proximal cancer per 50 g/day 0.95 Incidence, distal colon cancer ≥56 vs 0-4.9 g/d 0.91 Incidence, distal cancer per 50 g/day 0.94 Incidence, rectal cancer ≥56 vs 0-4.9 g/d 0.95 analysis
CUP_colorectal_SLR_2016_RO.docx