Table 144 Tea and colorectal cancer risk. Results of meta-analyses and pooled analyses of prospective studies published after the 2010 SLR. Total Number of cohort Studies Heterogeneity Author, Year number Outcome Comparison RR (95%CI) P studies country, area (I2, p value) of cases Pooled-analysis > 1400 g/day Incidence, colon (8-oz cups) 4 394 1.28 (1.02-1.61) cancer 1.04 (1.00-1.07) 0.50 13 Zhang, 2010 Worldwide 1.04 (1.00-1.09) proximal colon 2 277 0.64 cancer Per 250 g/day 1.04 (0.99-1.10) 1 795 distal cancer 0.34 Meta-analysis Incidence, 15 0.98 (0.93-1.03) 15%, 0.29 colorectal cancer Incidence, colon 12 1.00 (0.95-1.07) 28.3%, 0.17 Yu, 2014 Worldwide cancer Incidence, rectal 10 0.96 (0.88-1.04) 17.5%, 0.28 cancer
Table 144 Tea and colorectal cancer risk. Results of meta-analyses and pooled analyses of prospective studies published after the 2010 SLR. Author, Year Number of cohort studies Total number of cases Studies country, area Outcome Comparison RR (95%CI) P Heterogeneity (I2, p value) Pooled-analysis Zhang, 2010 13 4 394 Worldwide Incidence, colon cancer > 1400 g/day (8-oz cups) 1.28 (1.02-1.61) Per 250 g/day 1.04 (1.00-1.07) 0.50 2 277 proximal colon cancer 1.04 (1.00-1.09) 0.64 1 795 distal cancer 1.04 (0.99-1.10) 0.34 Meta-analysis Yu, 2014 15 Worldwide Incidence, colorectal cancer 0.98 (0.93-1.03) 15%, 0.29 12 Incidence, colon cancer 1.00 (0.95-1.07) 28.3%, 0.17 10 Incidence, rectal cancer 0.96 (0.88-1.04) 17.5%, 0.28
CUP_colorectal_SLR_2016_RO.docx