0.209 HEK293 cells expressing Estradiol-glucuronide (Campbell et al. 2004) OATP1B1 0.05 HEK293 cells expressing Estradiol-glucuronide (Hinton et al. 2008) + pre-incubation OATP1B1 0.47 HEK293 expressing Atorvastatin (Amundsen et al. 2010) largest number of OATP1B1 [CsA] 0.02 (Ki ~ 0.014) HEK293 cells expressing Atorvastatin (Amundsen et al. 2010) + pre-incubation OATP1B1 largest number of [CsA] 0.37* HeLa cells expressing Estradiol-glucuronide (Tirona et al. 2003) OATP1B1 0.31* HeLa cells expressing Rosuvastatin (Ho et al. 2006) OATP1B1 0.24* MDCK cells expressing Cerivastatin (Shitara et al. 2003) * includes IC50 data OATP1B1 in hepatocytes 0.24 MDCK cells expressing Pitavastatin (Hirano et al. 2006) ([CsA] not specified) OATP1B1 3.5 MDCK cells expressing Bromo-sulphthaleine (Letschert et al. 2006) ([CsA] not specified) OATP1B1 OATP1B3 (SLCO1B3) 0.57* HEK293 cells expressing Fexofenadine (Matsushima et al. 2008) OATP1B3 0.06* HeLa cells expressing Rosuvastatin (Ho et al. 2006) OATP1B3 0.3 MDCK cells expressing Bromo-sulphthaleine (Letschert et al. 2006) ([CsA] not specified) OATP1B1 0.3 MDCK cells expressing Amanitin (Letschert et al. 2006) ([CsA] not specified) OATP1B3 OATP2B1 (SLCO2B1)
0.209 HEK293 cells expressing OATP1B1 Estradiol-glucuronide (Campbell et al. 2004) 0.05 + pre-incubation HEK293 cells expressing OATP1B1 Estradiol-glucuronide (Hinton et al. 2008) 0.47 largest number of [CsA] HEK293 expressing OATP1B1 Atorvastatin (Amundsen et al. 2010) 0.02 (Ki ~ 0.014) + pre-incubation largest number of [CsA] HEK293 cells expressing OATP1B1 Atorvastatin (Amundsen et al. 2010) 0.37* HeLa cells expressing OATP1B1 Estradiol-glucuronide (Tirona et al. 2003) 0.31* HeLa cells expressing OATP1B1 Rosuvastatin (Ho et al. 2006) 0.24* * includes IC50 data in hepatocytes MDCK cells expressing OATP1B1 Cerivastatin (Shitara et al. 2003) 0.24 ([CsA] not specified) MDCK cells expressing OATP1B1 Pitavastatin (Hirano et al. 2006) 3.5 ([CsA] not specified) MDCK cells expressing OATP1B1 Bromo-sulphthaleine (Letschert et al. 2006) OATP1B3 (SLCO1B3) 0.57* HEK293 cells expressing OATP1B3 Fexofenadine (Matsushima et al. 2008) 0.06* HeLa cells expressing OATP1B3 Rosuvastatin (Ho et al. 2006) 0.3 ([CsA] not specified) MDCK cells expressing OATP1B1 Bromo-sulphthaleine (Letschert et al. 2006) 0.3 ([CsA] not specified) MDCK cells expressing OATP1B3 Amanitin (Letschert et al. 2006) OATP2B1 (SLCO2B1)
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