Incidence, physical activity, <.58 vs 2.5+ cancer, 1.04 (0.59-1.83) red meat intake, serving/week women smoking habits Table 11 Whole grain intake and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis Cases/ Author, Year, Study name, size Case Exposure RR (95%CI) Adjustment Reasons for WCRF Code, Outcome Comparison characteristics Follow-up ascertainment assessment Ptrend factors exclusion Country (years) Incidence, vs 0.61 ≥161 ≤75 colon cancer, g/day 0.86) men Incidence, 0.85 colon cancer, per 50 g men Incidence, 0.98 (0.88- per 50 g cancer, women 1.10) Alcohol intake, Incidence, vs 0.92 BMI, ≥161 ≤75 DCH, cancer, women g/day 1.35) educational Egeberg, 2010 Prospective 244/ level, leisure Included in HELGA Incidence, COL40841 Cohort, 55 819 Cancer registry FFQ vs 0.88 ≥161 ≤75 time physical (Kyro, 2013) rectal cancer, Denmark Age: 50-64 10.6 years g/day 1.36) activity, red men M/W and processed Incidence, 0.90 meat rectal cancer, per 50 g 1.01) men Incidence, 1.02 rectal cancer, per 50 g women Incidence, vs 0.81 ≥161 ≤75 rectal cancer, g/day 1.30) women
physical activity, red meat intake, smoking habits Incidence, cancer, women <.58 vs 2.5+ serving/week 1.04 (0.59-1.83) Table 11 Whole grain intake and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis Author, Year, WCRF Code, Country Study name, characteristics Cases/ size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Reasons for exclusion Egeberg, 2010 COL40841 Denmark DCH, Prospective Cohort, Age: 50-64 M/W 244/ 55 819 10.6 years Cancer registry FFQ Incidence, colon cancer, men ≥161 vs ≤75 g/day 0.61 Alcohol intake, BMI, educational level, leisure time physical activity, red and processed meat Included in HELGA (Kyro, 2013) Incidence, colon cancer, men per 50 g 0.85 Incidence, cancer, women per 50 g 0.98 Incidence, cancer, women ≥161 vs ≤75 g/day 0.92 Incidence, rectal cancer, men ≥161 vs ≤75 g/day 0.88 Incidence, rectal cancer, men per 50 g 0.90 Incidence, rectal cancer, women per 50 g 1.02 Incidence, rectal cancer, women ≥161 vs ≤75 g/day 0.81 (0.88- 1.30) 1.36) 1.10) 1.01) 1.35) 0.86)
CUP_colorectal_SLR_2016_RO.docx