exposure Cohort, energy intake, category. Age: 40-93 USA 8.5 years centres cancer, methionine, total of years, fat exposure W categories. The Pooling Age, BMI, Project Kim, calcium intake, 598/ 634.03-2555.2 2010 was used IWHS, energy intake, Incidence, 41 836 vs 32.14-231.12 1.12 (0.77-1.63) for dose Prospective estrogen use, cancer, Harnack, 2002 13 years mcg/day response Cohort, pack-years of COL00312 SEER analysis on Age: 55-69 FFQ smoking, USA colon cancer years, vitamin e W Oral 463.37-2555.2 Mid-points of Incidence, rectal contraceptive 123/ vs 32.14-281.85 0.89 (0.52-1.51) exposure cancer, use mcg/day categories. Age, beer consumption, New York date of University enrolment, date Women's Health of subsequent Kato, 1999 Incidence, Mid-points of Study, 150/ Follow-up vs blood, family ≥626 ≤224 COL00436 colorectal 0.88 (0.46-1.69) exposure Nested Case 81 questionnaire FFQ mcg/day history of USA cancer, categories. Control, specific cancer, Age: 62 years, menopausal W status, occult blood testing, physical activity 1996 ATBC, 86/ Incidence, colon 388 vs 268 COL00161 Nested Case Cancer registry FFQ 159 controls 0.51 (0.20-1.31) cancer mcg/day Finland Control, 8
USA Cohort, Age: 40-93 years, W 8.5 years centres cancer, energy intake, methionine, total fat exposure category. of exposure categories. Harnack, 2002 COL00312 USA IWHS, Prospective Cohort, Age: 55-69 years, W 598/ 41 836 13 years SEER FFQ Incidence, cancer, 634.03-2555.2 vs 32.14-231.12 mcg/day 1.12 (0.77-1.63) Age, BMI, calcium intake, energy intake, estrogen use, pack-years of smoking, vitamin e Oral contraceptive use The Pooling Project Kim, 2010 was used for dose response on colon cancer 123/ Incidence, rectal cancer, 463.37-2555.2 vs 32.14-281.85 mcg/day 0.89 (0.52-1.51) Mid-points of exposure categories. Kato, 1999 COL00436 USA New York University Women's Health Study, Nested Case Control, Age: 62 years, W 150/ 81 Follow-up questionnaire FFQ Incidence, colorectal cancer, ≥626 vs ≤224 mcg/day 0.88 (0.46-1.69) Age, beer consumption, date of enrolment, date of subsequent blood, family history of specific cancer, menopausal status, occult blood testing, physical activity Mid-points of exposure categories. 1996 COL00161 Finland ATBC, Nested Case Control, 86/ 159 controls 8 Cancer registry FFQ Incidence, colon cancer 388 vs 268 mcg/day 0.51 (0.20-1.31) analysis
CUP_colorectal_SLR_2016_RO.docx