344Height and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response meta-analysis Cases/ Author, Year, Missing data Study name, size Case Exposure RR (95%CI) Adjustment WCRF Code, Outcome Comparison derived for characteristics Follow-up ascertainment assessment Ptrend factors Country analyses > 179 vs < 170 Incidence, cm 5 617/ Alcohol, BMI, colorectal THIN, 15122 controls colonoscopy, Per 10 cm cancer, men 1.1 (1.05-1.15) Boursi, 2014 Nested Case connective increase Mid-point COL41032 Control, Medical records Medical records tissues disease, categories >165 vs <156 UK Age: 40- diabetes, heart 1.25 (1.12-1.39) Incidence, cm M/W 4 361/ disease, NSAID colorectal 11725 controls use, smoking Per 10 cm cancer, women 1.16 (1.1-1.23) increase 1 311/ Age, age at Self-reported Incidence, colon 481 197 1.19 (1.10-1.29) menarche, height cancer, women NIH-AARP, 10.5 alcohol, BMI, Prospective colonoscopy, Self-reported Incidence, Kabat, 2014 Cohort, Cancer registry 2 860/ 1.10 (1.05-1.16) educational height cancer, men COL41031 Age: 50-71 and national per 10 cm level, family USA years, death Index Self-reported Incidence, rectal history of 1 427/ 1.09 (1.02-1.17) M/W, height cancer, men cancer, physical Retired activity, race, Self-reported Incidence, rectal 591/ 1.12 (0.99-1.26) smoking height cancer, women 1 516/ WHI, Incidence, 144 701 1.19 (1.10-1.28) Kabat, 2013 Prospective Cancer registry colorectal cancer Self-reported 12 years COL40979 Cohort, and national height USA Age: 50-79 death Index 1 904/ Incidence, colon 1.18 (1.08-1.29) years, 144 701 cancer
344Height and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response meta-analysis Author, Year, WCRF Code, Country Study name, characteristics Cases/ size Follow-up Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Missing data derived for analyses Boursi, 2014 COL41032 UK THIN, Nested Case Control, Age: 40- M/W 5 617/ 15122 controls Medical records Medical records Incidence, colorectal cancer, men > 179 vs < 170 cm Alcohol, BMI, colonoscopy, connective tissues disease, diabetes, heart disease, NSAID use, smoking Mid-point categories Per 10 cm increase 1.1 (1.05-1.15) 4 361/ 11725 controls Incidence, colorectal cancer, women >165 vs <156 cm 1.25 (1.12-1.39) Per 10 cm increase 1.16 (1.1-1.23) Kabat, 2014 COL41031 USA NIH-AARP, Prospective Cohort, Age: 50-71 years, M/W, Retired 1 311/ 481 197 10.5 Cancer registry and national death Index Self-reported height Incidence, colon cancer, women per 10 cm 1.19 (1.10-1.29) Age, age at menarche, alcohol, BMI, colonoscopy, educational level, family history of cancer, physical activity, race, smoking 2 860/ Self-reported height Incidence, cancer, men 1.10 (1.05-1.16) 1 427/ Self-reported height Incidence, rectal cancer, men 1.09 (1.02-1.17) 591/ Self-reported height Incidence, rectal cancer, women 1.12 (0.99-1.26) Kabat, 2013 COL40979 USA WHI, Prospective Cohort, Age: 50-79 years, 1 516/ 144 701 12 years Cancer registry and national death Index Self-reported height Incidence, colorectal cancer 1.19 (1.10-1.28) 1 904/ 144 701 Incidence, colon cancer 1.18 (1.08-1.29)
CUP_colorectal_SLR_2016_RO.docx