Table 218 Alcohol (as ethanol) and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response analysis Cases/ Author, Year, Missing data Study name, Study size Case Exposure RR (95%CI) Adjustment WCRF Code, Outcome Comparison derived for characteristics Follow-up ascertainment assessment Ptrend factors Country analyses Incidence, rectal Age, BMI, 2655 1.48 (1.10-1.99) cancer, women cigarette 1 326 058 Distribution of smoking, family KNHIC, Korean central person-years by Incidence, colon history of 6492 1.31 (1.19-1.45) Shin, 2014 Prospective cancer registry exposure cancer, men cancer, fasting COL41023 Cohort, (kccr) & vs g/day category, ≥25 ≤0 blood sugar, Incidence, Korea Age: 30-80 years, Insurance questionnaire of height, meat 3555 colorectal 1.26 (1.18, M/W system exposure consumption, cancer, men categories. serum Incidence, rectal cholesterol 3146 1.26 (1.18-1.35) cancer, men Age, aspirin use, BMI, dietary calcium, endoscopy, energy intake, NHS, Medical records, family history of Prospective Nan, 2013 1 628/ pathology colorectal Cohort, Incidence, 1.30 (1.00-1.69) COL40971 87 856 reports, next of FFQ vs g/day cancer, height, Midpoints ≥30 ≤0 Age: 30-55 years, colorectal cancer Ptrend:0.15 USA 28 years kin, multivitamin W, certificate, ndi supplement Registered nurses intake, pack-yrs of smoking, physical activity, postmenopausal
Table 218 Alcohol (as ethanol) and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response Author, Year, WCRF Code, Country Study name, characteristics Cases/ Study size Follow-up Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Missing data derived for analyses Shin, 2014 COL41023 Korea KNHIC, Prospective Cohort, Age: 30-80 years, M/W 2655 1 326 058 Korean central cancer registry (kccr) & Insurance system questionnaire Incidence, rectal cancer, women ≥25 vs ≤0 g/day 1.48 (1.10-1.99) Age, BMI, cigarette smoking, family history of cancer, fasting blood sugar, height, meat consumption, serum cholesterol Distribution of person-years by exposure category, of exposure categories. 6492 Incidence, colon cancer, men 1.31 (1.19-1.45) 3555 Incidence, colorectal cancer, men 1.26 (1.18, 3146 Incidence, rectal cancer, men 1.26 (1.18-1.35) Nan, 2013 COL40971 USA NHS, Prospective Cohort, Age: 30-55 years, W, Registered nurses 1 628/ 87 856 28 years Medical records, pathology reports, next of kin, certificate, ndi FFQ Incidence, colorectal cancer ≥30 vs ≤0 g/day 1.30 (1.00-1.69) Ptrend:0.15 Age, aspirin use, BMI, dietary calcium, endoscopy, energy intake, family history of colorectal cancer, height, multivitamin supplement intake, pack-yrs of smoking, physical activity, postmenopausal Midpoints analysis
CUP_colorectal_SLR_2016_RO.docx