Table 300 Total physical activity and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis Cases/ Author, Year, name, Study size Case Exposure RR (95%CI) Adjustment Exclusion WCRF Code, Outcome Comparison characteristics Follow-up ascertainment assessment Ptrend factors reason Country (years) Makarem, 2015 Framingham 63/ Death certificate Questionnaire Incidence, Age, sex, per 1 0.95 (0.47-1.93) COL41060 Heart Study - 2 983 and medical colorectal cancer smoking status USA 11.5 years records Only continuous Cohort, results Prospective per 1 0.88 (0.43-1.78) Age Cohort, Age: 66.00years, M/W Hughes, 2011 Netherlands 321/ Incidence, Cancer registry Questionnaire Age, sex, COL40873 Cohort 5 000 Study on colorectal education level, Netherlands Diet 7.3 and years Cancer, cancer, energy intake, 1986-1997, smoking status, Case Cohort, socio-economic Age: 55-69 status, alcohol years, intake, family M/W high vs low 0.69 (0.47-1.01) history of Superseded by colorectal Simmons, 2013 cancer, fruit and vegetable, grains intake, physical activity, red meat consumption high vs low 0.67 (0.47-0.96)
Table 300 Total physical activity and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis Author, Year, WCRF Code, Country name, characteristics Cases/ Study size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Exclusion reason Makarem, 2015 COL41060 USA Framingham Heart Study - Cohort, Prospective Cohort, Age: 66.00years, M/W 63/ 2 983 11.5 years Death certificate and medical records Questionnaire Incidence, colorectal cancer per 1 0.95 (0.47-1.93) Age, sex, smoking status Only continuous results per 1 0.88 (0.43-1.78) Age Hughes, 2011 COL40873 Netherlands Netherlands Cohort Study on Diet and Cancer, 1986-1997, Case Cohort, Age: 55-69 years, M/W 321/ 5 000 7.3 years Cancer registry Questionnaire Incidence, colorectal cancer, high vs low 0.69 (0.47-1.01) Age, sex, education level, energy intake, smoking status, socio-economic status, alcohol intake, family history of colorectal cancer, fruit and vegetable, grains intake, physical activity, red meat consumption Superseded by Simmons, 2013 high vs low 0.67 (0.47-0.96)
CUP_colorectal_SLR_2016_RO.docx