Follow-up Country (years) Age, sex, Orlich, 2015 Adventist Health 490/ Cancer registry FFQ Incidence, 0.79 (0.64-0.97) alcohol, aspirin COL41043 Study 2, 77 659 colorectal cancer Ptrend:0.03 use, BMI, USA Prospective 7.3 years calcium Cohort, supplement, 380/ Incidence, colon 0.83 (0.66-1.05) M/W colonoscopy, cancer Ptrend:0.12 diabetes 305/ Incidence, medication use, 0.79 (0.61-1.03) colorectal educational Ptrend:0.08 cancer, women energy, family history of 185/ Men 0.81 (0.58-1.12) vegetarian vs colorectal Ptrend:0.20 non-vegetarian cancer, fibre 110/ Incidence, rectal 0.66 (0.43-1.02) Intake, history cancer Ptrend:0.06 of Inflammatory bowel disease, 106/ Incidence, 0.73 (0.47-1.14) history of peptic colorectal Ptrend:0.16 ulcer, HRT use, cancer, moderate 384 Incidence, activity, race, colorectal 0.81 (0.65-1.03) smoking, cancer, non- Ptrend:0.08 vitamin d black supplement Key, 2009 Oxford 384/ Incidence, UK national vegetarian vs COL40951 Vegetarian 61 566 colorectal cancer health service 1.49 (0.87, 1.44) quantitative FFQ meat UK Study 12.2 years central register
Country Follow-up (years) Orlich, 2015 COL41043 USA Adventist Health Study 2, Prospective Cohort, M/W 490/ 77 659 7.3 years Cancer registry FFQ Incidence, colorectal cancer vegetarian vs non-vegetarian 0.79 (0.64-0.97) Ptrend:0.03 Age, sex, alcohol, aspirin use, BMI, calcium supplement, colonoscopy, diabetes medication use, educational energy, family history of colorectal cancer, fibre Intake, history of Inflammatory bowel disease, history of peptic ulcer, HRT use, moderate activity, race, smoking, vitamin d supplement 380/ Incidence, colon cancer 0.83 (0.66-1.05) Ptrend:0.12 305/ Incidence, colorectal cancer, women 0.79 (0.61-1.03) Ptrend:0.08 185/ Men 0.81 (0.58-1.12) Ptrend:0.20 110/ Incidence, rectal cancer 0.66 (0.43-1.02) Ptrend:0.06 106/ Incidence, colorectal cancer, black 0.73 (0.47-1.14) Ptrend:0.16 384 Incidence, colorectal cancer, 0.81 (0.65-1.03) Ptrend:0.08 Key, 2009 COL40951 UK Oxford Vegetarian Study 384/ 61 566 12.2 years UK national health service central register FFQ Incidence, colorectal cancer vegetarian vs meat 1.49 (0.87, 1.44) non- quantitative
CUP_colorectal_SLR_2016_RO.docx