per 5 kg/m2 1.07 (0.86-1.33) 30 vs ≥ 3.26 (1.79-5.95) Incidence, distal Ptrend:<0.01 174/ colon cancer, kg/m2 men per 5 kg/m2 1.49 (1.19-1.87) 30 vs ≥ 1.43 (0.94-2.19) Incidence, Ptrend:0.07 237/ proximal colon kg/m2 cancer, women per 5 kg/m2 1.15 (0.99-1.34) 30 vs ≥ 1.65 (1.01-2.70) Incidence, distal Ptrend:0.01 159/ colon cancer, kg/m2 women per 5 kg/m2 1.25 (1.05-1.49) WHI Incidence, colon Self-report, Age, family per 10 1.81 (1.19-2.76) Prospective cancer medical record history of colon Cohort, 363/ Prentice, 2009 and pathology cancer, physical Age: 50-79 80 816 COL40811 report reviewed activity, years, 11 Incidence, rectal USA by centrally smoking status, per 10 units 0.62 (0.26-1.52) W, 87/ cancer trained alcohol, total postmenopausal physician energy intake women 30 vs < 20 1.42 (1.02-1.98) Jee, 2008 KNHIC, 4 671/ National cancer Weight and ≥ Incidence, colon kg/m2 Ptrend:<0.0001 COL40643 Prospective 1 213 829 registries, height cancer, men Korea 10.8 Cohort, years hospitalisation measurements per 1 kg/m2 1.06
per 5 kg/m2 1.07 (0.86-1.33) 174/ Incidence, distal colon cancer, men ≥ 30 vs kg/m2 3.26 (1.79-5.95) Ptrend:<0.01 per 5 kg/m2 1.49 (1.19-1.87) 237/ Incidence, proximal colon cancer, women ≥ 30 vs kg/m2 1.43 (0.94-2.19) Ptrend:0.07 per 5 kg/m2 1.15 (0.99-1.34) 159/ Incidence, distal colon cancer, women ≥ 30 vs kg/m2 1.65 (1.01-2.70) Ptrend:0.01 per 5 kg/m2 1.25 (1.05-1.49) Prentice, 2009 COL40811 USA WHI Prospective Cohort, Age: 50-79 years, W, postmenopausal women 363/ 80 816 11 87/ Self-report, medical record and pathology report reviewed by centrally trained physician Incidence, colon cancer per 10 1.81 (1.19-2.76) Age, family history of colon cancer, physical activity, smoking status, alcohol, total energy intake Incidence, rectal cancer per 10 units 0.62 (0.26-1.52) Jee, 2008 COL40643 Korea KNHIC, Prospective Cohort, 4 671/ 1 213 829 10.8 years National cancer registries, hospitalisation Weight and height measurements Incidence, colon cancer, men ≥ 30 vs < 20 kg/m2 1.42 (1.02-1.98) Ptrend:<0.0001 per 1 kg/m2 1.06
CUP_colorectal_SLR_2016_RO.docx