heavier vs never Ptrend:0.40 drinker UK Dietary 380 Incidence, colon Cohort vs <5 g/day 1.21(0.77-1.90) ≥30 7 studies cancer Consortium Incidence, rectal EPIC Norfolk 25000/318 0.93 (0.48-1.78) Mid-points of cancer exposure Age, weight, Incidence, categories. height, smoking EPIC Oxford 65249/121 colorectal 1.24(0.69-2.22) Overlaps with status, social cancer, men EPIC Park, 2010 intakes of energy, Guemsey Study 6127/28 (Bamia, 2013) fibre, folate, red meat and and Ferrari, Oxford processed meat. vs 0 g/day 2007 ≥45 Vegetarian 11140/31 Incidence, COL40648 Study colorectal 1.52(0.56-4.10) cancer, women NSHD 5362/ 7 35792/ 25 Whitehall II 10308/ 49 26/ Mortality, Age, BMI, vs ≥540 ≤0 Kangwha 6 291 colorectal 2.61 (0.88-7.78) Death educational level, Outcome is g/week Cohort, 20.8 cancer, men Yi, 2010 records/calls or ginseng intake, mortality. Prospective Questionnaire COL40798 follow up history of chronic Included only Mortality, colon vs 4.59 ≥540 ≤0 Cohort, and Interview 17/ Korea visits/death disease, pesticide in high versus cancer, men g/week Age: 55- years, certificates use, smoking lowest M/W Mortality, rectal vs ≥540 ≤0 habits 9/ 1.01 (0.16-6.25) cancer, men g/week Simons, 2010 NLCS, Cancer registry 1 260/ Incidence, >200 vs 0 1.32 (0.94-1.85) FFQ COL40821 Prospective and database of 120 852 colorectal ml/day Ptrend:0.16
heavier vs never drinker Ptrend:0.40 Park, 2010 UK Dietary Cohort Consortium 380 7 studies Incidence, colon cancer ≥30 vs <5 g/day 1.21(0.77-1.90) Age, weight, height, smoking status, social intakes of energy, fibre, folate, red meat and processed meat. Mid-points of exposure categories. Overlaps with EPIC (Bamia, 2013) and Ferrari, 2007 COL40648 EPIC Norfolk 25000/318 Incidence, rectal cancer 0.93 (0.48-1.78) EPIC Oxford 65249/121 Incidence, colorectal cancer, men ≥45 vs 0 g/day 1.24(0.69-2.22) Guemsey Study 6127/28 Incidence, colorectal cancer, women 1.52(0.56-4.10) Oxford Vegetarian Study 11140/31 NSHD 5362/ 7 35792/ 25 Whitehall II 10308/ 49 Yi, 2010 COL40798 Korea Kangwha Cohort, Prospective Cohort, Age: 55- years, M/W 26/ 6 291 20.8 Death records/calls or follow up visits/death certificates Questionnaire and Interview Mortality, colorectal cancer, men ≥540 vs ≤0 g/week 2.61 (0.88-7.78) Age, BMI, educational level, ginseng intake, history of chronic disease, pesticide use, smoking habits Outcome is mortality. Included only in high versus lowest 17/ Mortality, colon cancer, men ≥540 vs ≤0 g/week 4.59 9/ Mortality, rectal cancer, men ≥540 vs ≤0 g/week 1.01 (0.16-6.25) Simons, 2010 COL40821 NLCS, Prospective 1 260/ 120 852 Cancer registry and database of FFQ Incidence, colorectal >200 vs 0 ml/day 1.32 (0.94-1.85) Ptrend:0.16
CUP_colorectal_SLR_2016_RO.docx