Table 336 Waist to hip ratio and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response analysis Cases/ Author, Year, Missing data Study name, Study size Case Exposure RR (95%CI) Adjustment WCRF Code, Outcome Comparison derived for characteristics Follow-up ascertainment assessment Ptrend factors Country analyses (years) Age at baseline, 621/ Incidence, 1.01 (0.79-1.31) alcohol 72 972 colorectal cancer Ptrend:0.65 consumption, 11 years cigarette, Incidence, colon 0.96 (0.69-1.34) educational 381/ cancer Ptrend:0.92 level, energy SWHS, Follow up intake, family Li, 2013 Prospective survey/cancer history of Mid-point COL40937 Cohort, Measured vs ≥0.85 ≤0.77 registry/vital colorectal categories China Age: 40-70 statistics registry cancer, income, W menopausal Incidence, rectal 1.11 (0.74-1.66) 240/ status, physical cancer Ptrend:0.40 activity, intakes of red meat, tea, vegetables, fruits Age at baseline, 313/ Incidence, 1.65 (1.12-2.41) alcohol 61 283 colorectal cancer Ptrend:0.0004 consumption, 5.5 years cigarette, SMHS, educational Incidence, colon 1.97 (1.19-3.24) Prospective Follow up level, energy 169/ Li, 2013 cancer Ptrend:0.0004 Cohort, survey/cancer intake, family Mid-point COL40936 Measured vs ≥0.95 ≤0.85 Age: 40-74 history of categories China years, statistics registry colorectal M cancer, income, physical Incidence, rectal 1.24 (0.69-2.26) 133/ activity, intakes cancer Ptrend:0.20 of red meat, tea, vegetables,fruits
Table 336 Waist to hip ratio and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response Author, Year, WCRF Code, Country Study name, characteristics Cases/ Study size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Missing data derived for analyses Li, 2013 COL40937 China SWHS, Prospective Cohort, Age: 40-70 W 621/ 72 972 11 years Follow up survey/cancer registry/vital statistics registry Measured Incidence, colorectal cancer ≥0.85 vs ≤0.77 1.01 (0.79-1.31) Ptrend:0.65 Age at baseline, alcohol consumption, cigarette, educational level, energy intake, family history of colorectal cancer, income, menopausal status, physical activity, intakes of red meat, tea, vegetables, fruits Mid-point categories 381/ Incidence, colon cancer 0.96 (0.69-1.34) Ptrend:0.92 240/ Incidence, rectal cancer 1.11 (0.74-1.66) Ptrend:0.40 Li, 2013 COL40936 China SMHS, Prospective Cohort, Age: 40-74 years, M 313/ 61 283 5.5 years Follow up survey/cancer statistics registry Measured Incidence, colorectal cancer ≥0.95 vs ≤0.85 1.65 (1.12-2.41) Ptrend:0.0004 Age at baseline, alcohol consumption, cigarette, educational level, energy intake, family history of colorectal cancer, income, physical activity, intakes of red meat, tea, vegetables,fruits Mid-point categories 169/ Incidence, colon cancer 1.97 (1.19-3.24) Ptrend:0.0004 133/ Incidence, rectal cancer 1.24 (0.69-2.26) Ptrend:0.20 analysis
CUP_colorectal_SLR_2016_RO.docx