Table 101 Fish and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis Cases/ Author, Year, name, Study size Case Exposure RR (95%CI) Adjustment Reasons for WCRF Code, Outcome Comparison characteristics Follow-up ascertainment assessment Ptrend factors exclusion Country vs 0-27 ≥55 0.86 (0.68-1.08) Age, alcohol, g/day beef consumption, 644/ vs 0-27 ≥55 0.87 (0.70-1.08) Incidence, colon cold cuts, g/day 53 988 cancer educational 13.4 years level, energy, per 25 g/day 0.93 (0.85-1.01) DCH, fiber, HRT use, Superseded by Prospective Egeberg, 2013 lamb intake, Norat, 2005 per 25 g/day 0.94 (0.87-1.01) Cohort, COL40953 Cancer registry FFQ liver, NSAIS COL01698 Age: 50-64 Denmark use, pork, (component of vs 0-27 ≥55 years, 1.01 (0.72-1.40) poultry, EPIC g/day M/W processed meat, vs 0-27 ≥55 red meat, 0.97 (0.71-1.32) Incidence, rectal g/day 345/ sausages, cancer smoking, sport, per 25 g/day 0.99 (0.88-1.10) veal meat, waist circumference per 25 g/day 0.97 (0.88-1.08) Age, BMI, educational EPIC-Italy, Agnoli, 2013 435/ Cancer registry level, gender, Superseded by Prospective Incidence, 38.6-340.3 vs COL40938 45 275 and hospital 0.88 (0.68-1.13) non-alcoholic Bamia, 2013 Cohort, FFQ colorectal cancer g/day Trial 11.28 years records beverage intake, COL40964 M/W physical activity,
Table 101 Fish and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis Author, Year, WCRF Code, Country name, characteristics Cases/ Study size Follow-up Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Reasons for exclusion Egeberg, 2013 COL40953 Denmark DCH, Prospective Cohort, Age: 50-64 years, M/W 644/ 53 988 13.4 years Cancer registry FFQ Incidence, colon cancer ≥55 vs 0-27 g/day 0.86 (0.68-1.08) Age, alcohol, beef consumption, cold cuts, educational level, energy, fiber, HRT use, lamb intake, liver, NSAIS use, pork, poultry, processed meat, red meat, sausages, smoking, sport, veal meat, waist circumference Superseded by Norat, 2005 COL01698 (component of EPIC ≥55 vs 0-27 g/day 0.87 (0.70-1.08) per 25 g/day 0.93 (0.85-1.01) per 25 g/day 0.94 (0.87-1.01) 345/ Incidence, rectal cancer ≥55 vs 0-27 g/day 1.01 (0.72-1.40) ≥55 vs 0-27 g/day 0.97 (0.71-1.32) per 25 g/day 0.99 (0.88-1.10) per 25 g/day 0.97 (0.88-1.08) Agnoli, 2013 COL40938 EPIC-Italy, Prospective Cohort, M/W 435/ 45 275 11.28 years Cancer registry and hospital records FFQ Incidence, colorectal cancer 38.6-340.3 vs g/day 0.88 (0.68-1.13) Age, BMI, educational level, gender, non-alcoholic beverage intake, physical activity, Superseded by Bamia, 2013 COL40964 Trial
CUP_colorectal_SLR_2016_RO.docx