Table 331 Waist circumference and colorectal cancer risk. Results of meta- of prospective studies published after the 2010 SLR. Number of Studies Heterogeneity Author, Year cohort country, Outcome Comparison RR (95%CI) (I2, p value) studies area Colorectal cancer 1.45 (1.33-1.60) 10.8%, 0.32 Colon cancer 1.613 (1.417–1.837) 0.573, 0% Colon cancer, proximal 1.873 (1.118–3.136) 0.773, 0% Colon cancer, distal 1.942 (1.250–3.017) 0.507, 0% Rectal cancer 1.349 (1.114–1.634) 0.582, 0% USA Colorectal cancer 1.612 (1.379–1.885) 0.227, 24.3% Highest vs Ma, 2013 54 Europe Colorectal cancer 1.368 (1.215–1.541) 0.520, 0% lowest Colorectal cancer, men 1.477 (1.300–1.677) 0.135, 30.2% Colorectal cancer, women 1.442 (1.296–1.604) 0.834, 0% cancer, men 1.812 (1.464–2.242) 0.308, 15.9% Colon cancer, women 1.498 (1.253–1.791) 0.955, 0% Rectal cancer, men 1.281 (0.990–1.657) 0.934, 0% Rectal cancer, women 1.495 (1.025–2.181) 0.224, 33.1%
Table 331 Waist circumference and colorectal cancer risk. Results of meta- of prospective studies published after the 2010 SLR. Author, Year Number of cohort studies Studies country, area Outcome Comparison RR (95%CI) Heterogeneity (I2, p value) Ma, 2013 54 Colorectal cancer Highest vs lowest 1.45 (1.33-1.60) 10.8%, 0.32 Colon cancer 1.613 (1.417–1.837) 0.573, 0% Colon cancer, proximal 1.873 (1.118–3.136) 0.773, 0% Colon cancer, distal 1.942 (1.250–3.017) 0.507, 0% Rectal cancer 1.349 (1.114–1.634) 0.582, 0% USA Colorectal cancer 1.612 (1.379–1.885) 0.227, 24.3% Europe Colorectal cancer 1.368 (1.215–1.541) 0.520, 0% Colorectal cancer, men 1.477 (1.300–1.677) 0.135, 30.2% Colorectal cancer, women 1.442 (1.296–1.604) 0.834, 0% cancer, men 1.812 (1.464–2.242) 0.308, 15.9% Colon cancer, women 1.498 (1.253–1.791) 0.955, 0% Rectal cancer, men 1.281 (0.990–1.657) 0.934, 0% Rectal cancer, women 1.495 (1.025–2.181) 0.224, 33.1%
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