4 Tissue Any of the following if they 1 Non-conjugative culture cannot spontaneously plasmids generate a whole animal— 2 Non-viral vectors, (a) animal or human cell or replication cultures (including defective viral packaging cell lines); vectors unable to transduce human (b) isolated cells, isolated cells tissues or isolated organs, whether animal 3 Baculovirus or human; (Autographa californica (c) early non-human nuclear mammalian embryos polyhedrosis cultured in vitro virus), polyhedrin minus 4 None (non-vector systems) Either of the following if they 1 Non-tumorigenic are not intended, and are not disarmed Ti likely without human plasmid vectors, intervention, to vegetatively or Ri plasmid propagate, flower or vectors, in regenerate into a whole Agrobacterium plant— tumefaciens, Agrobacterium (a) plant cell cultures; or radiobacter (b) isolated plant tissues or Agrobacterium organs rhizogenes 2 Non-pathogenic vectors 3 None (non-vector systems) Sch. 2 __________________
4 Tissue culture Any of the following if they cannot spontaneously generate a whole animal— (a) animal or human cell cultures (including packaging cell lines); (b) isolated cells, isolated tissues or isolated organs, whether animal or human; (c) early non-human mammalian embryos cultured in vitro 1 Non-conjugative plasmids 2 Non-viral vectors, or replication defective viral vectors unable to transduce human cells 3 Baculovirus (Autographa californica nuclear polyhedrosis virus), polyhedrin minus 4 None (non-vector systems) Either of the following if they are not intended, and are not likely without human intervention, to vegetatively propagate, flower or regenerate into a whole plant— (a) plant cell cultures; (b) isolated plant tissues or organs 1 Non-tumorigenic disarmed Ti plasmid vectors, or Ri plasmid vectors, in Agrobacterium tumefaciens, Agrobacterium radiobacter or Agrobacterium rhizogenes 2 Non-pathogenic vectors 3 None (non-vector systems) Sch. 2 __________________
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