average energy intake per each quantile vs ≥172.08 53/ Incidence, ≤115.63 0.91 (0.69-1.19) 343 controls cancer mcg1000 kcal/day 805/ Distribution of 61 433 Incidence, vs 0-149 ≥212 person-years by 0.80 (0.60-1.06) Age, beta 911 042 colorectal cancer mcg/day exposure carotene, BMI, years category. calcium, cereal SMC, of Incidence, rectal vs 0-149 ≥212 fibre, 252/ 0.93 (0.55-1.56) Prospective exposure cancer mcg/day Larsson, 2005 educational Cohort, categories COL01852 Questionnaire level, Age: 40-75 Cancer registry Sweden methionine, red years, meat intake, Superseded by W saturated fat, Pooling Project vs 0-149 ≥212 547/ Incidence, 0.61 (0.41-0.91) total energy, Kim, 2010 for mcg/day cancer vitamin b6 colon cancer dose response meta-analysis BCDDP, 1973, Prospective Alcohol Flood, 2002 Breast cancer Incidence, Cohort, 485 vs consumption, ≥272 ≤142 COL00411 screening FFQ colorectal 0.86 (0.65-1.13) Age: 40-93 45 264 mcg/1000 kcal energy intake, USA centres cancer, years, 8.5 years methionine W 2002 CNBSS, Breast cancer 198/ Superseded by Quantitative Incidence, vs ≥367 ≤233 COL01158 Case Cohort, screening 56 837 0.60 (0.30-1.10) Pooling Project FFQ cancer, mcg/day Canada Age: 40-59 centres 10.4 years Kim, 2010 for
years average energy intake per each quantile 53/ 343 controls Incidence, cancer ≥172.08 vs ≤115.63 mcg1000 kcal/day 0.91 (0.69-1.19) Larsson, 2005 COL01852 Sweden SMC, Prospective Cohort, Age: 40-75 years, W 805/ 61 433 911 042 Cancer registry Questionnaire Incidence, colorectal cancer ≥212 vs 0-149 mcg/day 0.80 (0.60-1.06) Age, beta carotene, BMI, calcium, cereal fibre, educational level, methionine, red meat intake, saturated fat, total energy, vitamin b6 Distribution of person-years by exposure category. of exposure categories 252/ Incidence, rectal cancer ≥212 vs 0-149 mcg/day 0.93 (0.55-1.56) 547/ Incidence, cancer ≥212 vs 0-149 mcg/day 0.61 (0.41-0.91) Superseded by Pooling Project Kim, 2010 for colon cancer dose response meta-analysis Flood, 2002 COL00411 USA BCDDP, 1973, Prospective Cohort, Age: 40-93 years, W 485 45 264 8.5 years Breast cancer screening centres FFQ Incidence, colorectal cancer, ≥272 vs ≤142 mcg/1000 kcal 0.86 (0.65-1.13) Alcohol consumption, energy intake, methionine 2002 COL01158 Canada CNBSS, Case Cohort, Age: 40-59 198/ 56 837 10.4 years Breast cancer screening centres Quantitative FFQ Incidence, cancer, ≥367 vs ≤233 mcg/day 0.60 (0.30-1.10) Superseded by Pooling Project Kim, 2010 for
CUP_colorectal_SLR_2016_RO.docx