Author, Year, Study name, Study size Case Exposure RR (95%CI) WCRF Code, Outcome Comparison Adjustment factors characteristics Follow-up ascertainment assessment Ptrend Country (years) Alcohol intake, BMI, calcium Tasevska, NIH-AARP, 2 601/ US social security Incidence 0.99 intake, calcium supplement, 2012 Prospective 435 686 administration colorectal q 5 vs q 1 educational level, energy intake, COL40854 Cohort, death master FFQ cancer, men Ptrend:0.91 family history of colon cancer, fibre USA Age: 50-71 file/national death 1 296/ Incidence 1.05 intake, height, marital status, M/W, Index colorectal q 5 vs q 1 physical activity, race, red meat Retired cancer, women Ptrend:0.20 intake, smoking McCarl, 2006 IWHS, 954/ Seer registry FFQ Incidence, COL40633 Prospective 35 197 colorectal cancer USA Cohort, 15 years 0.87 vs g Age ≥31.6 ≤13.9 Age: 55-69 years, W Michaud, NHS-HPFS, 1 096/ Incidence, Self-report, 0.87 FFQ 2005 Prospective 130 719 colorectal medical 68 vs record 22 g/day and 1.07) COL01824 Cohort, 20 years cancer, women pathology report Ptrend:0.2 USA M/W reviewed by 858/ Incidence, colon 0.86 centrally trained cancer, women 68 vs 22 g/day physician Ptrend:0.15 238/ Incidence, rectal 0.92 cancer, 68 vs 22 g/day Ptrend:0.47 683/ Incidence, 1.37 colorectal 72 vs 29 g/day cancer, men Ptrend:0.008 552/ Incidence, colon 1.38 cancer, men 72 vs 29 g/day Ptrend:0.02
Author, Year, WCRF Code, Country Study name, characteristics Study size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Tasevska, 2012 COL40854 USA NIH-AARP, Prospective Cohort, Age: 50-71 M/W, Retired 2 601/ 435 686 US social security administration death master file/national death Index FFQ Incidence colorectal cancer, men q 5 vs q 1 0.99 Ptrend:0.91 Alcohol intake, BMI, calcium intake, calcium supplement, educational level, energy intake, family history of colon cancer, fibre intake, height, marital status, physical activity, race, red meat intake, smoking 1 296/ Incidence colorectal cancer, women q 5 vs q 1 1.05 Ptrend:0.20 McCarl, 2006 COL40633 USA IWHS, Prospective Cohort, Age: 55-69 years, W 954/ 35 197 15 years Seer registry FFQ Incidence, colorectal cancer ≥31.6 vs ≤13.9 g 0.87 Age Michaud, 2005 COL01824 USA NHS-HPFS, Prospective Cohort, M/W 1 096/ 130 719 20 years Self-report, medical record and pathology report reviewed by centrally trained physician FFQ Incidence, colorectal cancer, women 68 vs 22 g/day 0.87 Ptrend:0.2 858/ Incidence, colon cancer, women 68 vs 22 g/day 0.86 Ptrend:0.15 238/ Incidence, rectal cancer, 68 vs 22 g/day 0.92 Ptrend:0.47 683/ Incidence, colorectal cancer, men 72 vs 29 g/day 1.37 Ptrend:0.008 552/ Incidence, colon cancer, men 72 vs 29 g/day 1.38 Ptrend:0.02 1.07)
CUP_colorectal_SLR_2016_RO.docx