Ptrend:0.70 Distal colon, 1.48 (0.90-2.42) 131/ men Ptrend:0.12 Distal colon, 0.66 (0.36-1.21) 85/ women Ptrend:0.25 1.20 (0.81-1.78) 200/ Rectum, all Ptrend:0.35 1.38 (0.83-2.27) 134/ Rectum, men Ptrend:0.21 0.95 (0.50-1.79) 66/ Rectum, women Ptrend:0.89 Used in NHS & HPFS, Age, aspirin, 861/ stratified Pooled analysis, calcium, caloric 156 703 1.52 (1.19-1.93) analysis by sex (W) nurses and Self-report intake, folate, 2 631 423 Ptrend:0.0001 only (M) health Morikawa, 2013 (provided red meat, vit D, person-years professionals COL40958 evidence of Weight multivitamin, Mid-point & treatment), measured, Incidence, 30 vs < 18.5 smoking status, NHS, ≥ categories 493/ 1.55 (1.16-2.06) COL40959 medical records height was colorectal cancer kg/m2 alcohol, family Prospective 109 046 Ptrend:0.001 and pathology in 1976 history CRC, Cohort, W Hamling method USA reports, national sigmoidoscopy, used to death Index physical activity HPFS, recalculate the 368/ 1.30 (0.83-2.03) smoking, HRT Prospective RR’s 47 684 Ptrend:0.14 use Cohort, M
Ptrend:0.70 131/ Distal colon, men 1.48 (0.90-2.42) Ptrend:0.12 85/ Distal colon, women 0.66 (0.36-1.21) Ptrend:0.25 200/ Rectum, all 1.20 (0.81-1.78) Ptrend:0.35 134/ Rectum, men 1.38 (0.83-2.27) Ptrend:0.21 66/ Rectum, women 0.95 (0.50-1.79) Ptrend:0.89 Morikawa, 2013 COL40958 & COL40959 USA NHS & HPFS, Pooled analysis, (W) nurses and (M) health professionals 861/ 156 703 2 631 423 person-years Self-report (provided evidence of treatment), medical records and pathology reports, national death Index Weight measured, height was in 1976 Incidence, colorectal cancer ≥ 30 vs < 18.5 kg/m2 1.52 (1.19-1.93) Ptrend:0.0001 Age, aspirin, calcium, caloric intake, folate, red meat, vit D, multivitamin, smoking status, alcohol, family history CRC, sigmoidoscopy, physical activity smoking, HRT use Used in stratified analysis by sex only Mid-point categories Hamling method used to recalculate the RR’s NHS, Prospective Cohort, W 493/ 109 046 1.55 (1.16-2.06) Ptrend:0.001 HPFS, Prospective Cohort, M 368/ 47 684 1.30 (0.83-2.03) Ptrend:0.14
CUP_colorectal_SLR_2016_RO.docx