years, intake, physical colon cancer W activity, dose response smoking habits, meta-analysis total fat intake Distribution of Incidence, rectal vs person-years by ≥367 ≤233 97/ 0.70 (0.30-1.80) cancer, mcg/day exposure category. Age, sex, 219/ Incidence, colon vs ≥249 ≤103.3 0.57 (0.34-0.97) alcohol Distribution of 10 011 cancer, mcg/day NHANES I, consumption, person-years by Prospective vs ≥249 ≤103.3 Su, 2001 educational exposure 120/ Women 0.74 (0.36-1.51) Cohort, Population 24h-Recall mcg/day COL00547 level, ethnicity, category. Age: 25-74 registry questionnaire USA intakes of of years, energy, fat, exposure vs ≥249 ≤103.3 M/W 99/ Men 0.40 (0.18-0.88) vitamin B12, categories. mcg/day vitamin B6 Age, alcohol consumption, NHS, aspirin use, beef, Superseded by Prospective pork or lamb Giovannucci, 219/ Incidence, colon Pooling Project Cohort, Hospital rectods intake, BMI, 1998 88 756 cancer, using vs Kim, 2010 for ≥300 ≤200 Age: 30-55 and National 0.82 (0.56-1.20) family history of COL00113 1 215 392 FFQ supplements <15 mcg/day colon cancer years, Index specific cancer, USA person-years years dose response W, methionine, meta-analysis. nurses physical activity, smoking habits
years, W intake, physical activity, smoking habits, total fat intake colon cancer dose response meta-analysis 97/ Incidence, rectal cancer, ≥367 vs ≤233 mcg/day 0.70 (0.30-1.80) Distribution of person-years by exposure category. Su, 2001 COL00547 USA NHANES I, Prospective Cohort, Age: 25-74 years, M/W 219/ 10 011 Population registry 24h-Recall questionnaire Incidence, colon cancer, ≥249 vs ≤103.3 mcg/day 0.57 (0.34-0.97) Age, sex, alcohol consumption, educational level, ethnicity, intakes of energy, fat, vitamin B12, vitamin B6 Distribution of person-years by exposure category. of exposure categories. 120/ Women ≥249 vs ≤103.3 mcg/day 0.74 (0.36-1.51) 99/ Men ≥249 vs ≤103.3 mcg/day 0.40 (0.18-0.88) Giovannucci, 1998 COL00113 USA NHS, Prospective Cohort, Age: 30-55 years, W, nurses 219/ 88 756 1 215 392 person-years Hospital rectods and National Index FFQ Incidence, colon cancer, using supplements <15 years ≥300 vs ≤200 mcg/day 0.82 (0.56-1.20) Age, alcohol consumption, aspirin use, beef, pork or lamb intake, BMI, family history of specific cancer, methionine, physical activity, smoking habits Superseded by Pooling Project Kim, 2010 for colon cancer dose response meta-analysis.
CUP_colorectal_SLR_2016_RO.docx