vs 0.76 (0.53-1.09) Incidence, distal ≥27.5 ≤16.1 g/day Ptrend:0.12 746/ colon cancer, women per 10 g/day 0.87 (0.73-1.05) per 10 g/day 0.89 (0.73-1.08) Incidence, distal 520/ colon cancer, vs 0.68 (0.44-1.05) ≥30.6 ≤17.3 Men g/day Ptrend:0.061 per 10 g/day 0.96 (0.79-1.16) Incidence, 478/ proximal colon vs 0.95 (0.62-1.47) ≥30.6 ≤17.3 cancer, men g/day Ptrend:0.77 Age, BMI, 1 470/ Incidence, vs 1.06 (0.67-1.70) ≥21.3 ≤9.8 dietary calcium, 158 800 colorectal cancer g/day Ptrend:0.97 educational 7.8 years level, energy Incidence, intake, family vs 1.20 (0.73-1.95) ≥21.3 ≤9.8 798/ proximal colon history of g/day Ptrend:0.97 Women's Health cancer Mail or colorectal Initiative - telephone cancer, fibre, Incidence, distal vs 0.97 (0.46-2.05) ≥21.3 ≤9.8 Observational 351/ Kabat, 2008 questionnaires height, history Mid-points of cancer g/day Ptrend:0.94 study, COL40722 verified by FFQ of diabetes, exposure Prospective USA trained hormone use, categories Cohort, physician number of W, adjudicators cigarettes Postmenopausal smoked, Incidence, rectal vs 0.88 (0.39-2.01) ≥21.3 ≤9.8 303/ observational cancer g/day Ptrend:0.39 study participants, physical activity Schatzkin, 2007 NIH-AARP, Cancer registry FFQ 2 974/ Incidence, 15.9 vs 6.6 0.99 (0.85-1.15)
746/ Incidence, distal colon cancer, women ≥27.5 vs ≤16.1 g/day 0.76 (0.53-1.09) Ptrend:0.12 per 10 g/day 0.87 (0.73-1.05) 520/ Incidence, distal colon cancer, Men per 10 g/day 0.89 (0.73-1.08) ≥30.6 vs ≤17.3 g/day 0.68 (0.44-1.05) Ptrend:0.061 478/ Incidence, proximal colon cancer, men per 10 g/day 0.96 (0.79-1.16) ≥30.6 vs ≤17.3 g/day 0.95 (0.62-1.47) Ptrend:0.77 Kabat, 2008 COL40722 USA Women's Health Initiative - Observational study, Prospective Cohort, W, Postmenopausal 1 470/ 158 800 7.8 years Mail or telephone questionnaires verified by trained physician adjudicators FFQ Incidence, colorectal cancer ≥21.3 vs ≤9.8 g/day 1.06 (0.67-1.70) Ptrend:0.97 Age, BMI, dietary calcium, educational level, energy intake, family history of colorectal cancer, fibre, height, history of diabetes, hormone use, number of cigarettes smoked, observational study participants, physical activity Mid-points of exposure categories 798/ Incidence, proximal colon cancer ≥21.3 vs ≤9.8 g/day 1.20 (0.73-1.95) Ptrend:0.97 351/ Incidence, distal cancer ≥21.3 vs ≤9.8 g/day 0.97 (0.46-2.05) Ptrend:0.94 303/ Incidence, rectal cancer ≥21.3 vs ≤9.8 g/day 0.88 (0.39-2.01) Ptrend:0.39 Schatzkin, 2007 NIH-AARP, 2 974/ Cancer registry FFQ Incidence, 15.9 vs 6.6 0.99 (0.85-1.15)
CUP_colorectal_SLR_2016_RO.docx