cancer, men mg/day Ptrend:0.10 activity, smoking status, 1.54 vs 0.47 1.20 (0.83-1.74) total energy 484/ Women mg/day Ptrend:0.56 intake, vegetable intake Incidence, rectal 1.85 vs 0.6 0.98 (0.64-1.50) 333/ cancer, men mg/day Ptrend:0.84 1.54 vs 0.47 1.23 (0.73-2.07) 185/ Women mg/day Ptrend:0.11 Age, BMI, calcium intake, Incidence, colon 1.31 (0.98-1.75) calendar period, Distribution of SMC, cancer Ptrend:0.03 dietary fibre person-years by Prospective Larsson, 2005 547/ intake, exposure Cohort, vs ≥2.06 ≤0.66 COL40745 61 433 Cancer Registry FFQ educational category. Age: 40-75 mg/day Sweden 14.8 years level, folate of years, intake, saturated exposure Alcohol intake 2.29 (1.25- 4.21) W fat, total energy categories Ptrend:0.007 ≥20g/week intake, zinc intake Age, alcohol 438/ Incidence, vs 2.18 (1.24-3.86) ≥2.05 ≤0.76 IWHS, consumption, 34 708 proximal colon mg/day Ptrend:0.01 Prospective BMI, calcium, 15 years cancer, Lee, 2004 Cohort, diabetes, fibre, Mid-points of COL00285 Age: 55-69 SEER FFQ folate, HRT use, exposure USA years, multivitamin categories Incidence, distal vs 0.90 (0.45-1.81) ≥2.05 ≤0.76 W, 303/ supplement colon cancer, mg/day Ptrend:0.77 Postmenopausal intake, physical activity,
activity, smoking status, total energy intake, vegetable intake cancer, men mg/day Ptrend:0.10 484/ Women 1.54 vs 0.47 mg/day 1.20 (0.83-1.74) Ptrend:0.56 333/ Incidence, rectal cancer, men 1.85 vs 0.6 mg/day 0.98 (0.64-1.50) Ptrend:0.84 185/ Women 1.54 vs 0.47 mg/day 1.23 (0.73-2.07) Ptrend:0.11 Larsson, 2005 COL40745 Sweden SMC, Prospective Cohort, Age: 40-75 years, W 547/ 61 433 14.8 years Cancer Registry FFQ Incidence, colon cancer ≥2.06 vs ≤0.66 mg/day 1.31 (0.98-1.75) Ptrend:0.03 Age, BMI, calcium intake, calendar period, dietary fibre intake, educational level, folate intake, saturated fat, total energy intake, zinc intake Distribution of person-years by exposure category. of exposure categories Alcohol intake ≥20g/week 2.29 (1.25- 4.21) Ptrend:0.007 Lee, 2004 COL00285 USA IWHS, Prospective Cohort, Age: 55-69 years, W, Postmenopausal 438/ 34 708 15 years SEER FFQ Incidence, proximal colon cancer, ≥2.05 vs ≤0.76 mg/day 2.18 (1.24-3.86) Ptrend:0.01 Age, alcohol consumption, BMI, calcium, diabetes, fibre, folate, HRT use, multivitamin supplement intake, physical activity, Mid-points of exposure categories 303/ Incidence, distal colon cancer, ≥2.05 vs ≤0.76 mg/day 0.90 (0.45-1.81) Ptrend:0.77
CUP_colorectal_SLR_2016_RO.docx