cancer, women Ptrend:0.17 683/ Incidence, 1.30 colorectal 67 vs 26 g/day cancer, men Ptrend:0.03 552/ Incidence, colon 1.25 cancer, men 67 vs 26 g/day Ptrend:0.13 131/ Incidence, rectal 1.47 cancer, men 67 vs 26 g/day Ptrend:0.11 Age, alcohol consumption, BMI, WHS, 174/ Cancer registry FFQ Incidence, 1.51 energy-adjusted calcium, 2004 Prospective 38 451 colorectal cancer q 5 vs q 1 folate, energy-adjusted COL00299 Cohort, 7.9 years Ptrend:0.06 fat, energy-adjusted vitamin d, USA Age: 45- energy-adjusted total fiber, family W, history of specific cancer, history of nurses 1.08 per 10 g/day oral contraceptive use, HRT use, nsaid use, physical activity, smoking habits, total energy Bostick, 1994 IWHS, 212/ Driving license Incidence, colon Age, energy intake, height, parity, COL00079 Prospective 35 216 cancer 1.45 vs total vitamin e intake, total vitamin ≥62.5 ≤25.8 USA Cohort, 167 447 FFQ g/day e intake * age, vitamin a Age: 55-69 Ptrend:0.14 supplement W Table Fructose intake and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response meta-analysis
cancer, women Ptrend:0.17 683/ Incidence, colorectal cancer, men 67 vs 26 g/day 1.30 Ptrend:0.03 552/ Incidence, colon cancer, men 67 vs 26 g/day 1.25 Ptrend:0.13 131/ Incidence, rectal cancer, men 67 vs 26 g/day 1.47 Ptrend:0.11 2004 COL00299 USA WHS, Prospective Cohort, Age: 45- W, nurses 174/ 38 451 7.9 years Cancer registry FFQ Incidence, colorectal cancer q 5 vs q 1 1.51 Ptrend:0.06 Age, alcohol consumption, BMI, energy-adjusted calcium, folate, energy-adjusted fat, energy-adjusted vitamin d, energy-adjusted total fiber, family history of specific cancer, history of oral contraceptive use, HRT use, nsaid use, physical activity, smoking habits, total energy per 10 g/day 1.08 Bostick, 1994 COL00079 USA IWHS, Prospective Cohort, Age: 55-69 W 212/ 35 216 167 447 Driving license FFQ Incidence, colon cancer ≥62.5 vs ≤25.8 g/day 1.45 Ptrend:0.14 Age, energy intake, height, parity, total vitamin e intake, total vitamin e intake * age, vitamin a supplement Table Fructose intake and colorectal cancer risk. Main characteristics of studies included in the CUP SLR dose-response meta-analysis
CUP_colorectal_SLR_2016_RO.docx