Mean exposure Age, date of NYUWHS, reported only Questionnaire, enrolment, date Kato, 1999 Nested Case Questionnaire, 105/ medical records, Incidence, of subsequent COL00436 Control, medical records, Kaaks, 2000 15 785 National Death colorectal cancer blood, USA Age: 62.00years, cancer registries COL40787 Index menopausal W Used in HvsL status analysis > 2.71 vs < 2.3 1.64 (0.92-2.92) g/cm2 Ptrend:0.04 Incidence, colon NHSCD, cancer, men > 2.71 vs < 2.3 1.61 (0.76-3.44) Prospective Gaard, 1997 Thune, 1996 g/cm2 Ptrend:0.21 Cohort, 62 173 Cardiovascular COL00163 Measured Age COL00269 Age: 20-54 702 010 screening > 2.66 vs < 2.17 1.02 (0.53-1.97) Norway used instead years, g/cm2 Ptrend:0.88 Incidence, colon M/W cancer, women > 2.66 vs < 2.17 0.64 (0.31-1.33) g/cm2 Ptrend:0.8 NYUWHS, Prospective 100/ Kato, 1997 Questionnaire, Superseded by Cohort, 14 272 Incidence, Age, place at CRC00022 medical records, Self-reported Q4 vs Q4 1.19 (0.68-2.08) Kaaks, 2000 Age: 34-65 105 044 colorectal cancer enrolment USA cancer registries COL40787 years, W 393/ Age, alcohol Martínez, 1997 NHS, Medical records, 89 448 Incidence, colon 1.45 (1.02-2.07) consumption, COL00139 Prospective National Death Self-reported 1 012 375 cancer Ptrend:0.04 cigarette USA Cohort, Index person-years smoking, family
Kato, 1999 COL00436 USA NYUWHS, Nested Case Control, Age: 62.00years, W 105/ 15 785 Questionnaire, medical records, cancer registries Questionnaire, medical records, National Death Index Incidence, colorectal cancer Age, date of enrolment, date of subsequent blood, menopausal status Mean exposure reported only Kaaks, 2000 COL40787 Used in HvsL analysis Gaard, 1997 COL00163 Norway NHSCD, Prospective Cohort, Age: 20-54 years, M/W 62 173 702 010 Cardiovascular screening Measured Incidence, colon cancer, men > 2.71 vs < 2.3 g/cm2 1.64 (0.92-2.92) Ptrend:0.04 Age Thune, 1996 COL00269 used instead > 2.71 vs < 2.3 g/cm2 1.61 (0.76-3.44) Ptrend:0.21 Incidence, colon cancer, women > 2.66 vs < 2.17 g/cm2 1.02 (0.53-1.97) Ptrend:0.88 > 2.66 vs < 2.17 g/cm2 0.64 (0.31-1.33) Ptrend:0.8 Kato, 1997 CRC00022 USA NYUWHS, Prospective Cohort, Age: 34-65 years, W 100/ 14 272 105 044 Questionnaire, medical records, cancer registries Self-reported Incidence, colorectal cancer Q4 vs Q4 1.19 (0.68-2.08) Age, place at enrolment Superseded by Kaaks, 2000 COL40787 Martínez, 1997 COL00139 USA NHS, Prospective Cohort, 393/ 89 448 1 012 375 person-years Medical records, National Death Index Self-reported Incidence, colon cancer 1.45 (1.02-2.07) Ptrend:0.04 Age, alcohol consumption, cigarette smoking, family
CUP_colorectal_SLR_2016_RO.docx