Apc+ cases vs g/day 0.56 (0.24-1.30) ≥20 ≤0 57/ per 15.1 g/day 0.83 (0.63-1.07) Incidence, colon cancer, hmlh1- vs g/day 0.73 (0.73-2.53) ≥20 ≤0 54/ cases per 15.1 g/day 0.81 (0.58-1.14) OVS, Sanjoaquin, Only included in Prospective 95/ Incidence, Alcohol 2004 vs highest ≥1 ≤0 Cohort, 10 998 FFQ colorectal 1.17 (0.71-1.92) consumption, COL01182 compared to Age: 18-89 17 years cancer, smoking habits UK lowest analysis M/W 15/ Mortality, Age, smoking Outcome is HCS, 3 458 colorectal Q 2 vs Q 1 0.30 (0.00-2.30) habits mortality Prospective 14.3 years cancer, men Khan, 2004 Cohort, Area residency COL01606 Questionnaire Health Age: 40-97 lists education, Outcome is years, 14/ Women Q 2 vs Q 1 1.90 (0.50-6.90) health screening, mortality M/W health status Age, alcohol 129/ Mortality, colon vs 0-2 ≥5 consumption, 107 824 0.97 (0.62-1.50) cancer, women times/week JACC, BMI, 10 years Prospective educational Kojima, 2004 Resident registry vs 0-2 ≥5 Cohort, level, family Outcome is 123/ Men 1.04 (0.65-1.66) COL01840 and Questionnaire times/week Age: 40-79 history of mortality Japan certificates years, specific cancer, Mortality, rectal vs 0-2 ≥5 103/ 0.95 (0.60-1.51) M/W physical cancer, men times/week activity, region 48/ Women vs 0-2 0.90 (0.44-1.84) of enrolment, ≥5
57/ Apc+ cases ≥20 vs ≤0 g/day 0.56 (0.24-1.30) per 15.1 g/day 0.83 (0.63-1.07) 54/ Incidence, colon cancer, hmlh1- cases ≥20 vs ≤0 g/day 0.73 (0.73-2.53) per 15.1 g/day 0.81 (0.58-1.14) Sanjoaquin, 2004 COL01182 UK OVS, Prospective Cohort, Age: 18-89 M/W 95/ 10 998 17 years FFQ Incidence, colorectal cancer, ≥1 vs ≤0 1.17 (0.71-1.92) Alcohol consumption, smoking habits Only included in highest compared to lowest analysis Khan, 2004 COL01606 HCS, Prospective Cohort, Age: 40-97 years, M/W 15/ 3 458 14.3 years Area residency lists Questionnaire Mortality, colorectal cancer, men Q 2 vs Q 1 0.30 (0.00-2.30) Age, smoking habits Outcome is mortality 14/ Women Q 2 vs Q 1 1.90 (0.50-6.90) Health education, health screening, health status Outcome is mortality Kojima, 2004 COL01840 Japan JACC, Prospective Cohort, Age: 40-79 years, M/W 129/ 107 824 10 years Resident registry and certificates Questionnaire Mortality, colon cancer, women ≥5 vs 0-2 times/week 0.97 (0.62-1.50) Age, alcohol consumption, BMI, educational level, family history of specific cancer, physical activity, region of enrolment, Outcome is mortality 123/ Men ≥5 vs 0-2 times/week 1.04 (0.65-1.66) 103/ Mortality, rectal cancer, men ≥5 vs 0-2 times/week 0.95 (0.60-1.51) 48/ Women ≥5 vs 0-2 0.90 (0.44-1.84)
CUP_colorectal_SLR_2016_RO.docx