Gpx1 pro198leu smoking, COL41009 38/ per 10 g/day 1.02 (0.53-1.97) tt Age, sex, alcohol intake, BMI, diabetes, dialect SCHS, educational Prospective level, energy Butler, 2008 961/ Only included in Cohort, Incidence, 0.98 (0.81-1.19) intake, COL40639 61 321 Cancer registry FFQ Q 4 vs Q 1 highest versus Age: 45-74 colorectal cancer Ptrend:0.78 exposure Singapore 9.8 years lowest analysis years, assessment, M/W family history of colorectal cancer, physical activity, smoking habits IWHS, Prospective McCarl, 2006 954/ Included in Cohort, Incidence, vs ≥25.4 ≤13.2 COL40633 35 197 SEER registry FFQ 0.75 (0.61-0.92) Age Pooling Project Age: 55-69 colorectal cancer g/day USA 15 years (Park, 2005) years, W 1 118/ 519 978 Incidence, colon vs 0.77 (0.58-1.02) ≥29.5 ≤15.9 EPIC, registries, 2 279 075 cancer, men g/day Ptrend:0.01 Prospective Bingham, 2005 mortality person-years Cohort, COL40747 registries, health FFQ Age: 25-70 Incidence, rectal vs 0.81 (0.55-1.21) ≥29.5 ≤15.9 Europe Insurance 603/ years, cancer, men g/day Ptrend:0.5 records, active M/W follow up Incidence, left vs 0.58 (0.39-0.86) ≥29.5 ≤15.9 496/ colon cancer, g/day Ptrend:<0.001
smoking, COL41009 38/ Gpx1 pro198leu tt per 10 g/day 1.02 (0.53-1.97) Butler, 2008 COL40639 Singapore SCHS, Prospective Cohort, Age: 45-74 years, M/W 961/ 61 321 9.8 years Cancer registry FFQ Incidence, colorectal cancer Q 4 vs Q 1 0.98 (0.81-1.19) Ptrend:0.78 Age, sex, alcohol intake, BMI, diabetes, dialect educational level, energy intake, exposure assessment, family history of colorectal cancer, physical activity, smoking habits Only included in highest versus lowest analysis McCarl, 2006 COL40633 USA IWHS, Prospective Cohort, Age: 55-69 years, W 954/ 35 197 15 years SEER registry FFQ Incidence, colorectal cancer ≥25.4 vs ≤13.2 g/day 0.75 (0.61-0.92) Age Included in Pooling Project (Park, 2005) Bingham, 2005 COL40747 Europe EPIC, Prospective Cohort, Age: 25-70 years, M/W 1 118/ 519 978 2 279 075 person-years registries, mortality registries, health Insurance records, active follow up FFQ Incidence, colon cancer, men ≥29.5 vs ≤15.9 g/day 0.77 (0.58-1.02) Ptrend:0.01 603/ Incidence, rectal cancer, men ≥29.5 vs ≤15.9 g/day 0.81 (0.55-1.21) Ptrend:0.5 496/ Incidence, left colon cancer, ≥29.5 vs ≤15.9 g/day 0.58 (0.39-0.86) Ptrend:<0.001
CUP_colorectal_SLR_2016_RO.docx