Japan Cohort, 15 years registration use vs no use 0.86 (0.46-1.59) Age: 40-79 records, 158/ Mortality, rectal years, certificates use vs no use 0.61 (0.19-1.92) cancer, men M/W 84/ use vs no use 1.36 (0.62-3.00) Wu, 2002 NHS, 626/ Self-reported, Incidence, colon vitamin E COL00905 Prospective 87 998 hospital records FFQ cancer and Alcohol 0.88 (0.66-1.16) USA Cohort, 16 years and National multivitamin vs consumption, Age: 30-55 Death Index never users aspirin use, years, BMI, family 0.87 (0.68-1.11) W, vs iu/day ≥99 ≤0 history of Ptrend:37 nurses colorectal vs 0.78 (0.43-1.42) ≥600 ≤0 cancer, iu/day Ptrend:0.29 menopausal status, HPFS, 370/ Incidence, colon vitamin E suppl of Prospective 47 344 FFQ cancer and 0.82 (0.60–1.11) smoking, Cohort, 10 multivitamin vs physical Age: 40-75 never users activity, years, postmenopausal 355/ 0.77 (0.57-1.02) M, vs iu/day ≥99 ≤0 hormone use, Ptrend:0.06 Health red meat intake professionals vs 0.70 (0.38-1.29) ≥600 ≤0 iu/day Ptrend:0.06 Jacobs, 2001 CPS 4 336/ II, Mortality, Self-reported Questionnaire COL00296 Prospective 711 891 colorectal and vs National year 1.08 (0.85-1.38) ≥10 ≤0 USA, Puerto 14 Cohort, years cancer, Death Index Rico Age: 30- years, 2 430/ Men vs year 1.13 (0.82-1.57) ≥10 ≤0
Japan Cohort, Age: 40-79 years, M/W 15 years registration records, certificates use vs no use 0.86 (0.46-1.59) 158/ Mortality, rectal cancer, men use vs no use 0.61 (0.19-1.92) 84/ use vs no use 1.36 (0.62-3.00) Wu, 2002 COL00905 USA NHS, Prospective Cohort, Age: 30-55 years, W, nurses 626/ 87 998 16 years Self-reported, hospital records and National Death Index FFQ Incidence, colon cancer vitamin E and multivitamin vs never users 0.88 (0.66-1.16) Alcohol consumption, aspirin use, BMI, family history of colorectal cancer, menopausal status, of smoking, physical activity, postmenopausal hormone use, red meat intake ≥99 vs ≤0 iu/day 0.87 (0.68-1.11) Ptrend:37 ≥600 vs ≤0 iu/day 0.78 (0.43-1.42) Ptrend:0.29 HPFS, Prospective Cohort, Age: 40-75 years, M, Health professionals 370/ 47 344 10 FFQ Incidence, colon cancer vitamin E suppl and multivitamin vs never users 0.82 (0.60–1.11) 355/ ≥99 vs ≤0 iu/day 0.77 (0.57-1.02) Ptrend:0.06 ≥600 vs ≤0 iu/day 0.70 (0.38-1.29) Ptrend:0.06 Jacobs, 2001 COL00296 USA, Puerto Rico CPS II, Prospective Cohort, Age: 30- years, 4 336/ 711 891 14 years Self-reported and National Death Index Questionnaire Mortality, colorectal cancer, ≥10 vs ≤0 year 1.08 (0.85-1.38) 2 430/ Men ≥10 vs ≤0 year 1.13 (0.82-1.57)
CUP_colorectal_SLR_2016_RO.docx