Example 3(k)-4: Ambiguity symbols other than are defined” “n” “specifically A patent application describes the following sequence: 5’ NNG KNG KNG KAG VCR 3’ wherein N, K, V, and R are IUPAC-IUB ambiguity codes Question 1: Does ST.26 require inclusion of the sequence(s)? YES IUPAC-IUB ambiguity codes correspond to the list of nucleotide symbols defined in Annex I, Section 1, Table 1. According to paragraph 3(k), a defined” nucleotide is any nucleotide other than those represented by “specifically the symbol listed in Annex I, Section 1, Table 1. Therefore, and are defined” “n” “K”, “V”, “R” “specifically nucleotides. The sequence has eleven enumerated and defined” nucleotides and is required by ST.26 paragraph “specifically 7(a) to be included in a sequence listing. Question 3: How should the sequence(s) be represented in the sequence listing? The sequence must be included in a sequence listing as: nngkngkngkagvcr (SEQ ID NO: 16) Relevant ST.26 paragraphs: Paragraphs 3(k), 7(a) and 15
Example 3(k)-4: Ambiguity symbols other than “n” are “specifically defined” A patent application describes the following sequence: 5’ NNG KNG KNG KAG VCR 3’ wherein N, K, V, and R are IUPAC-IUB ambiguity codes Question 1: Does ST.26 require inclusion of the sequence(s)? YES IUPAC-IUB ambiguity codes correspond to the list of nucleotide symbols defined in Annex I, Section 1, Table 1. According to paragraph 3(k), a “specifically defined” nucleotide is any nucleotide other than those represented by the symbol “n” listed in Annex I, Section 1, Table 1. Therefore, “K”, “V”, and “R” are “specifically defined” nucleotides. The sequence has eleven enumerated and “specifically defined” nucleotides and is required by ST.26 paragraph 7(a) to be included in a sequence listing. Question 3: How should the sequence(s) be represented in the sequence listing? The sequence must be included in a sequence listing as: nngkngkngkagvcr (SEQ ID NO: 16) Relevant ST.26 paragraphs: Paragraphs 3(k), 7(a) and 15
cws_6_16-annex6.docx