Table 306 Recreational physical activity and colorectal cancer risk. Results of pooled analyses of prospective studies published after the 2010 SLR. Number of Total Studies Author, P Heterogeneity cohort number of country, Outcome Comparison RR (95%CI) Year trend (p value) studies cases area Europe, Proximal colon 21 cohort 9512 0.73(0.66-0.81) North cancer and 31.3%, 0.06 Boyle, 2012 America, Highest vs lowest 0%, 0.47 Japan, 8171 Distal colon cancer 0.74(0.68-0.80) studies Australia Europe, Highest vs lowest 0.74(0.61 - 0.14 28 cohort North Men Yang, 2010 Colon cancer studies America, Highest vs lowest 0.99(0.95 0.41 – Asia Women Highest vs lowest 0.80 (0.67-0.96) 54.1%, 0.01 Men Colon cancer Europe, Highest vs lowest 0.86 (0.76-0.98) 0%, 0.88 North Women Harris, 2009 15 7873 America, Highest vs lowest 1.02 (0.83-1.26) 8.1%, 0.37 Japan Men Rectal cancer Highest vs lowest 1.29 (0.82-2.01) 29.5%, 0.24 Women
Table 306 Recreational physical activity and colorectal cancer risk. Results of pooled analyses of prospective studies published after the 2010 SLR. Author, Year Number of cohort studies Total number of cases Studies country, area Outcome Comparison RR (95%CI) P trend Heterogeneity (p value) Boyle, 2012 21 cohort and studies 9512 Europe, North America, Japan, Australia Proximal colon cancer Highest vs lowest 0.73(0.66-0.81) 31.3%, 0.06 0%, 0.47 8171 Distal colon cancer 0.74(0.68-0.80) Yang, 2010 28 cohort studies Europe, North America, Asia Colon cancer Highest vs lowest Men 0.74(0.61 - 0.14 Highest vs lowest Women 0.99(0.95 – 0.41 Harris, 2009 15 7873 Europe, North America, Japan Colon cancer Highest vs lowest Men 0.80 (0.67-0.96) 54.1%, 0.01 Highest vs lowest Women 0.86 (0.76-0.98) 0%, 0.88 Rectal cancer Highest vs lowest Men 1.02 (0.83-1.26) 8.1%, 0.37 Highest vs lowest Women 1.29 (0.82-2.01) 29.5%, 0.24
CUP_colorectal_SLR_2016_RO.docx