307 Recreational physical activity and colorectal cancer risk. Main characteristics of studies included in the CUP SLR meta-analysis Cases/ Author, Year, Case name, Study size Exposure RR (95%CI) Adjustment Reasons for WCRF Code, Outcome Comparison characteristics Follow-up assessment Ptrend factors exclusion Country (years) Age, alcohol consumption, estrogen use, family history of NSABP P-1, cancer, Prospective menstrual status, Land, 2014 Cohort, 35/ Incidence, Follow-up low/no activity race, smoking COL41062 Age: 54 years, 13 388 Questionnaire invasive colon 0.90 visits vs more active status, treatment USA W, 7 years cancer allocation, High Risk asprine use, population smoking duration, smoking intensity Incidence, 377/ distal 4 416 0.69 (0.50-0.96) cancer, 16 years women Incidence, NLCS, 227/ rectal cancer, 0.59 (0.39-0.90) Prospective Simons, 2013 women Cohort, Cancer COL40956 Self-report Age: 55-69 registry Incidence, Netherlands years, 1 107/ colon cancer, 1.06 (0.84-1.33) M/W men Incidence, 438/ rectal cancer, 1.10 (0.80-1.52) men 581/ Incidence, 1.18 (0.88-1.60)
307 Recreational physical activity and colorectal cancer risk. Main characteristics of studies included in the CUP SLR meta-analysis Author, Year, WCRF Code, Country name, characteristics Cases/ Study size Follow-up (years) Case Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Reasons for exclusion Land, 2014 COL41062 USA NSABP P-1, Prospective Cohort, Age: 54 years, W, High Risk population 35/ 13 388 7 years Follow-up visits Questionnaire Incidence, invasive colon cancer low/no activity vs more active 0.90 Age, alcohol consumption, estrogen use, family history of cancer, menstrual status, race, smoking status, treatment allocation, asprine use, smoking duration, smoking intensity Simons, 2013 COL40956 Netherlands NLCS, Prospective Cohort, Age: 55-69 years, M/W 377/ 4 416 16 years Cancer registry Self-report Incidence, distal cancer, women 0.69 (0.50-0.96) 227/ Incidence, rectal cancer, women 0.59 (0.39-0.90) 1 107/ Incidence, colon cancer, men 1.06 (0.84-1.33) 438/ Incidence, rectal cancer, men 1.10 (0.80-1.52) 581/ Incidence, 1.18 (0.88-1.60)
CUP_colorectal_SLR_2016_RO.docx