Table 240 Multivitamin use and colorectal cancer risk. Results of meta-analyses and pooled analyses of prospective studies published after the 2005 SLR. Number of Total Studies Heterogeneity Author, Year cohort number of Outcome Comparison RR (95%CI) P trend country, area (I2, p value) studies cases Pooled analysis 13 5454 44 ATBC 467+349 CPS II 456 HPFS 393 NLCS 335+223 NYSC North 349 Colon cancer 0.88(0.81-0.96) 0.17 Park, 2010 America and Users vs non users 431 CNBSS incidence 799 Europe IWHS 353 NLCS 96 NYUWHS 162+429 NHS 43 485 SMC 40 WHS Meta-analysis Colorectal and North 7 8737 colon cancer 0.92(0.87-0.97) 4.9%, 0.39 America and Users vs Europe incidence
Table 240 Multivitamin use and colorectal cancer risk. Results of meta-analyses and pooled analyses of prospective studies published after the 2005 SLR. Author, Year Number of cohort studies Total number of cases Studies country, area Outcome Comparison RR (95%CI) P trend Heterogeneity (I2, p value) Pooled analysis Park, 2010 13 ATBC CPS II HPFS NLCS NYSC CNBSS IWHS NLCS NYUWHS NHS SMC WHS 5454 44 467+349 456 393 335+223 349 431 799 353 96 162+429 43 485 40 North America and Europe Colon cancer incidence Users vs non users 0.88(0.81-0.96) 0.17 Meta-analysis 7 8737 North America and Europe Colorectal and colon cancer incidence Users vs 0.92(0.87-0.97) 4.9%, 0.39
CUP_colorectal_SLR_2016_RO.docx