certificate and Age: 40-79 symptoms geographic highest versus years, described by location, smoking lowest analysis M family members Incidence, colorectal per 1 sd units 1.83 (1.10-3.04) EPIC-Norfolk, cancer, gc:at Gay, 2012 Prospective 185/ mutations Superseded by 7-day dietary COL40920 Cohort, 25 636 Cancer registry Age, sex, smoking Bamia, 2013 recalls Apc promoter COL40964 UK Age: 45-79 11 years methylation per 1 sd units 1.10 (0.75-1.61) M/W ≥20% Apc mutations per 1 sd 1.63 (1.13-2.35) Age, BMI, calcium, energy intake, NLCS, Bongaerts, Cancer registry adjusted intake of Prospective Bongaerts, 2011 594/ 2008 was used and database of Incidence, vs fat, family history Cohort, ≥30 COL40825 120 852 FFQ 0.91 (0.59-1.41) because it has Age: 55-69 pathology colorectal cancer abstainers g/day of colorectal Netherlands 7.3 years higher number years, reports cancer, fibre, of cases M/W gender, physical activity
Age: 40-79 years, M certificate and symptoms described by family members geographic location, smoking highest versus lowest analysis Gay, 2012 COL40920 UK EPIC-Norfolk, Prospective Cohort, Age: 45-79 M/W 185/ 25 636 11 years Cancer registry 7-day dietary recalls Incidence, colorectal cancer, gc:at mutations per 1 sd units 1.83 (1.10-3.04) Age, sex, smoking Superseded by Bamia, 2013 COL40964 Apc promoter methylation ≥20% per 1 sd units 1.10 (0.75-1.61) Apc mutations per 1 sd 1.63 (1.13-2.35) Bongaerts, 2011 COL40825 Netherlands NLCS, Prospective Cohort, Age: 55-69 years, M/W 594/ 120 852 7.3 years Cancer registry and database of pathology reports FFQ Incidence, colorectal cancer ≥30 vs abstainers g/day 0.91 (0.59-1.41) Age, BMI, calcium, energy intake, intake of fat, family history of colorectal cancer, fibre, gender, physical activity Bongaerts, 2008 was used because it has higher number of cases adjusted
CUP_colorectal_SLR_2016_RO.docx