Table 134 Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis. Author, Year, Study name, Study size Case Exposure RR (95%CI) Adjustment Reasons for WCRF Code, Outcome Comparison characteristics Follow-up ascertainment assessment Ptrend factors exclusion Country (years) Age, alcohol, 325/ Incidence, >2 vs <1 0.89 (0.66-1.19) BMI, diabetes, 61 321 advanced cups/day Ptrend:0.40 dialect group, 9.8 years cancer educational SCHS, level, family Peterson, 2010 Prospective Cancer registry Advanced and history of COL40820 Cohort, and pathology localized colon colorectal 229/ Incidence, Singapore Age: 45-74 register cancer >2 vs <1 0.82 (0.59-1.14) cancer, gender, 61 321 localized colon M/W cups/day Ptrend:0.24 green tea, 9.8 years cancer physical activity, smoking, year 741/ 61 467 Incidence, vs ≥4 ≤1 1.00 (0.70-1.30) 823 072 colorectal cancer cups/day Age, alcohol SMC, intake, BMI, Prospective 504/ Mucci, 2006 educational Superseded by Cohort, 61 467 Incidence, vs ≥4 ≤1 COL40750 Cancer registry FFQ level, energy Larsson, 2006 1.10 (0.80-1.50) Age: 40-75 823 072 cancer cups/day Sweden intake, fibre COL40628 years, intake, saturated W fat 237/ 61 467 Incidence, rectal vs ≥4 ≤1 0.90 (0.60-1.40) 823 072 cancer cups/day
Table 134 Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis. Author, Year, WCRF Code, Country Study name, characteristics Study size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Reasons for exclusion Peterson, 2010 COL40820 Singapore SCHS, Prospective Cohort, Age: 45-74 M/W 325/ 61 321 9.8 years Cancer registry and pathology register Incidence, advanced cancer >2 vs <1 cups/day 0.89 (0.66-1.19) Ptrend:0.40 Age, alcohol, BMI, diabetes, dialect group, educational level, family history of colorectal cancer, gender, green tea, physical activity, smoking, year Advanced and localized colon cancer 229/ 61 321 9.8 years Incidence, localized colon cancer >2 vs <1 cups/day 0.82 (0.59-1.14) Ptrend:0.24 Mucci, 2006 COL40750 Sweden SMC, Prospective Cohort, Age: 40-75 years, W 741/ 61 467 823 072 Cancer registry FFQ Incidence, colorectal cancer ≥4 vs ≤1 cups/day 1.00 (0.70-1.30) Age, alcohol intake, BMI, educational level, energy intake, fibre intake, saturated fat Superseded by Larsson, 2006 COL40628 504/ 61 467 823 072 Incidence, cancer ≥4 vs ≤1 cups/day 1.10 (0.80-1.50) 237/ 61 467 823 072 Incidence, rectal cancer ≥4 vs ≤1 cups/day 0.90 (0.60-1.40)
CUP_colorectal_SLR_2016_RO.docx