Table 279 Dietary vitamin C and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis Cases/ Author, Year, Study name, Study size Case Exposure RR (95%CI) Adjustment Reasons for WCRF Code, Outcome Comparison characteristics Follow-up ascertainment assessment Ptrend factors exclusion Country (years) Age, body mass index, education, physical activity, family history of Studies 5454/676141 colorectal ATBC 44 cancer, use of CPS II 467+349 nonsteroidal HPFS 456 NLCS 393 NYSC 335+223 Self-reported drugs, Only included in BCDDP 349 Park, 2010 questionnaire Incidence, colon 1.06(0.95-1.18) multivitamin highest CNBSS 431 FFQ Q5 vs Q1 Pooling Project and medical cancer P 0.12 use, smoking, compared to IWHS 799 lowest analysis record alcohol NLCS 353 consumption, NYUWHS 96 intakes of red NHS 162+429 meat, total milk, ORDET 43 dietary folate SMC 485 and total energy, WHS 40 and use of postmenopausal hormone therapy (premenopausal, never, ever) and oral
Table 279 Dietary vitamin C and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR dose-response meta-analysis Author, Year, WCRF Code, Country Study name, characteristics Cases/ Study size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Reasons for exclusion Park, 2010 Pooling Project Studies ATBC CPS II HPFS NLCS NYSC BCDDP CNBSS IWHS NLCS NYUWHS NHS ORDET SMC WHS 5454/676141 44 467+349 456 393 335+223 349 431 799 353 96 162+429 43 485 40 Self-reported questionnaire and medical record FFQ Incidence, colon cancer Q5 vs Q1 1.06(0.95-1.18) P 0.12 Age, body mass index, education, physical activity, family history of colorectal cancer, use of nonsteroidal drugs, multivitamin use, smoking, alcohol consumption, intakes of red meat, total milk, dietary folate and total energy, and use of postmenopausal hormone therapy (premenopausal, never, ever) and oral Only included in highest compared to lowest analysis
CUP_colorectal_SLR_2016_RO.docx