Table 151 Green tea consumption and colon cancer risk. Main characteristics of studies included in the CUP SLR dose-response analysis Author, Year, Missing data name, Study size Case Exposure RR (95%CI) Adjustment WCRF Code, Outcome Comparison derived for characteristics Follow-up ascertainment assessment Ptrend factors Country analyses (years) Age, education, Yes vs no 0.69 (0.48-0.98) cigarette smoking, of cigarette smoking, alcohol SMHS, consumption, Prospective Yang, 2011 133/ Cancer registry regular exercise, Cohort, Incidence, colon Mid-point Body Mass COL40885 60 567 and medical Survey vs 0.85 (0.62-1.15) Age: 40-74 cancer ≥250 ≤0 exposure Index, China 4.6 years records Ptrend:0.27 years, history of diabetes, family M history of colorectal cancer and intakes of vegetables, fruits and red meat Age, alcohol 476/ Incidence, colon JPHC, Active patient drinking, beef Mid-point 96 162 0.92 (0.63–1.33) cancer, men Lee, 2007 Prospective notification from consumption, exposure 10 Questionnaire cups/day ≥5 COL40654 Cohort, hospitals, cancer black tea FFQ vs almost never Japan Age: 52 years, registries and consumption, Person-years of Incidence, colon 284/ 1.1 (0.7-1.73) M/W death cert. BMI, Chinese follow up cancer, women tea, family
Table 151 Green tea consumption and colon cancer risk. Main characteristics of studies included in the CUP SLR dose-response Author, Year, WCRF Code, Country name, characteristics Study size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Missing data derived for analyses Yang, 2011 COL40885 China SMHS, Prospective Cohort, Age: 40-74 years, M 133/ 60 567 4.6 years Cancer registry and medical records Survey Incidence, colon cancer Yes vs no 0.69 (0.48-0.98) Age, education, cigarette smoking, of cigarette smoking, alcohol consumption, regular exercise, Body Mass Index, history of diabetes, family history of colorectal cancer and intakes of vegetables, fruits and red meat Mid-point exposure ≥250 vs ≤0 0.85 (0.62-1.15) Ptrend:0.27 Lee, 2007 COL40654 Japan JPHC, Prospective Cohort, Age: 52 years, M/W 476/ 96 162 10 Active patient notification from hospitals, cancer registries and death cert. Questionnaire FFQ Incidence, colon cancer, men ≥5 cups/day vs almost never 0.92 (0.63–1.33) Age, alcohol drinking, beef consumption, black tea consumption, BMI, Chinese tea, family Mid-point exposure Person-years of follow up 284/ Incidence, colon cancer, women 1.1 (0.7-1.73) analysis
CUP_colorectal_SLR_2016_RO.docx