201013 201114 201115 201016 Evidence is: Occupational SB Leisure time SB TV and SB Depression No. of studies 43 19 48 11 Study design x-s p p x-s c-c p p BMI and x-s 5/10 p 4/10 p 13/18 Mixed weight gain c-c 0 p 1/3 Diabetes x-s 1/1 p 2/2 p 4/4 Moderate c-c - p 2/3 p 3/7 Mixed biomarkers c-c ½ p 2/4 p 1/1 Mixed p 3/6 disease Cancers p 4/4 p p Mixed 1/13 4/5 Depression x-s 6/10 Limited p 2/2 All-cause p 4/6 p 2/3 p 6/6 Strong or mortality convincing Study design: x-s=cross sectional; c-c=case control; p=prospective. The conclusions from the three main reviews were that the majority of the prospective studies found that occupational/leisure time sitting was associated with higher risk of mortality. There was moderate or mixed evidence of relationships between sitting time and diabetes and a range of weight related health outcomes, including weight gain and obesity, and insufficient evidence to support any relationship for cancer or CVD (including CVD biomarkers).13-15 Although the level and strength of the evidence appears to be increasing, heterogeneity of study designs, measures and findings made it difficult to draw definitive conclusions. The review that focussed only on depression
201013 Occupational SB 201114 Leisure time SB 201115 TV and SB 201016 Depression Evidence is: No. of studies 43 19 48 11 Study design x-s c-c p p p x-s p BMI and weight gain x-s 5/10 c-c 0 p 1/3 p 4/10 p 13/18 Mixed Diabetes x-s 1/1 c-c - p 2/3 p 2/2 p 4/4 Moderate biomarkers p 3/7 Mixed disease c-c ½ p 3/6 p 2/4 p 1/1 Mixed Cancers p 4/4 p 1/13 p 4/5 Mixed Depression x-s 6/10 p 2/2 Limited All-cause mortality p 4/6 p 2/3 p 6/6 Strong or convincing Study design: x-s=cross sectional; c-c=case control; p=prospective. The conclusions from the three main reviews were that the majority of the prospective studies found that occupational/leisure time sitting was associated with higher risk of mortality. There was moderate or mixed evidence of relationships between sitting time and diabetes and a range of weight related health outcomes, including weight gain and obesity, and insufficient evidence to support any relationship for cancer or CVD (including CVD biomarkers).13-15 Although the level and strength of the evidence appears to be increasing, heterogeneity of study designs, measures and findings made it difficult to draw definitive conclusions. The review that focussed only on depression
DEB-PAR-Adults-18-64years.DOCX