3 year group (0.36 ± 0.69) years vs compared to placebo placebo group (0.82 ± 1.17) P=0.02 5.6.3 Calcitriol, acetylsalicylic acid, and calcium carbonate Author, Year, Cases Case Study name, Treatment/ RR (95%CI) Country Treatment/ Outcome characteristics comparison Ptrend control name Pommergaard, 2015 Men and aged 40-75 52/58 colonoscopy Adenoma Treatment vs 0.94 (0.60–1.48) years with previous adenoma, Europe, USA, Russia, 3 years recurrence placebo 209 assigned to 0.5 μg assessed calcitriol, 75 mg acetylsalicylic acid, and 1250 mg calcium carbonate each day for 3 years, 218 with placebo
3 year years vs placebo group (0.36 ± 0.69) compared to placebo group (0.82 ± 1.17) P=0.02 5.6.3 Calcitriol, acetylsalicylic acid, and calcium carbonate Author, Year, Country name Study name, characteristics Cases Treatment/ control Case Outcome Treatment/ comparison RR (95%CI) Ptrend Pommergaard, 2015 Europe, USA, Russia, Men and aged 40-75 years with previous adenoma, 209 assigned to 0.5 μg calcitriol, 75 mg acetylsalicylic acid, and 1250 mg calcium carbonate each day for 3 years, 218 with placebo 52/58 colonoscopy 3 years Adenoma recurrence assessed Treatment vs placebo 0.94 (0.60–1.48)
CUP_colorectal_SLR_2016_RO.docx