Description causal but it is not Pediatrics 128 of included conclusive (1): 103-110 studies: 18 studies were Effect size: Type of included in Multivariate source: the meta of 7 case Systematic analysis. 5 control studies breast review were feeding versus no conducted in breastfeeding SOR 0.55 Protective the UK, 3 (95% CI 0.44 to 0.69) factor: USA, 2 Breastfeeding Scandinavia, Author’s conclusions: 5 Australasia, Breastfeeding is Study 2 Germany, 1 protective against Population: Canada. SIDS, and this effect is SIDs assume Included stronger when infants up to 1 studies were breastfeeding is year conducted exclusive. The between 1952 recommendation to Searches and 2003. breastfeed infants were should be included with conducted Quality of other SIDS between: Jan included messages to 1966 and studies: both reduce the risk of December Quality SIDS and promote 2009 assessed breastfeeding for its American many other infant and Included Academy of maternal health study types: Pediatrics benefits. Case control Task Force on studies positioning Comment: Whilst the and SIDS association appears criteria. All strong the reliability of included the findings is studies met compromised due to all criteria. reliance on one source of studies and lack of Synthesis: check for publication Meta analysis bias, thus there is the possibility that negative Findings: studies have been Eighteen missed. Further, NICE case-control guidance 37.1 raises studies were concerns about included in matching in the some of the studies.
Pediatrics 128 (1): 103-110 Type of source: Systematic review Protective factor: Breastfeeding Study Population: SIDs assume infants up to 1 year Searches were conducted between: Jan 1966 and December 2009 Included study types: Case control studies Description of included studies: 18 studies were included in the meta analysis. 5 were conducted in the UK, 3 USA, 2 Scandinavia, 5 Australasia, 2 Germany, 1 Canada. Included studies were conducted between 1952 and 2003. Quality of included studies: Quality assessed American Academy of Pediatrics Task Force on positioning and SIDS criteria. All included studies met all criteria. Synthesis: Meta analysis Findings: Eighteen case-control studies were included in the causal but it is not conclusive Effect size: Multivariate of 7 case control studies breast feeding versus no breastfeeding SOR 0.55 (95% CI 0.44 to 0.69) Author’s conclusions: Breastfeeding is protective against SIDS, and this effect is stronger when breastfeeding is exclusive. The recommendation to breastfeed infants should be included with other SIDS messages to both reduce the risk of SIDS and promote breastfeeding for its many other infant and maternal health benefits. Comment: Whilst the association appears strong the reliability of the findings is compromised due to reliance on one source of studies and lack of check for publication bias, thus there is the possibility that negative studies have been missed. Further, NICE guidance 37.1 raises concerns about matching in some of the studies.
CDR%20Research%20Evidence%20Review%20SUID%20report%20FINAL%20091014.docx