TGF Causes problems in Losartan, exp3179  β-1 lungs, autoimmune, (experimental) or VIP Neuro (tremor, learning disability, MS, TM) (need chilled tubes) If AGA, gluten free and check 1st manifestation of Gluten free X 3 months, then  Tissue Trans-glutaminase autoimmunity, grain recheck intolerance MMP9/ADH-Osm/ As noted Actos/low amylose diet (if  Androgens can all be lumped above/below Leptin >7, but Omega-3’s if together Leptin <7) ADH/Osm Thirst, skin shocks DDAVP nasal/monitor Na  Obesity, DM Improves with CIRS Tx , can Leptin VIP, MSH  Sleep disturbances, Due to low Leptin activity on MSH chronic pain, Hypothalamus (Leptin levels enthesopathy, be may ) GI/malabsorption, leaky gut, prolonged illness, resistant Staph, Pituitary/Adrenal axis disruption, Reduced sex hormones, reduced ADH Poor perfusion/cell VEGF starvation, Exercise intolerance Hypoperfusion, Actos/low amylose diet (if C4a lactosis, low Leptin >7, but Omega-3’s if glutamate/glutamine Leptin <7), VIP on MR Spectroscopy Brain fog, HA, myalgias, thermoregulation, Exercise intolerance Actos/low amylose diet (if C3a Leptin >7, but Omega-3’s if Leptin <7), VIP Actos/low amylose diet (if Androgens Leptin >7, but Omega-3’s if Leptin <7), DHEA 2) Medication Effects; Cholestyramine, Welchol Absorbs Gut Toxins BEG/Rifampin Kills MARCONS Actos/Low Amylose if Leptin >7 (otherwise Lowers MMP9, TNF, PIE-1, Leptin Omega-3’s) Losartan Lowers TGF β-1
 TGF β-1 Causes problems in lungs, autoimmune, Neuro (tremor, learning disability, MS, TM) (need chilled tubes) Losartan, exp3179 (experimental) or VIP If  AGA, gluten free and check Tissue Trans-glutaminase 1st manifestation of autoimmunity, grain intolerance Gluten free X 3 months, then recheck  MMP9/ADH-Osm/ Androgens can all be lumped together As noted above/below Actos/low amylose diet (if Leptin >7, but Omega-3’s if Leptin <7) ADH/Osm Thirst, skin shocks DDAVP nasal/monitor  Na Leptin Obesity, DM Improves with CIRS Tx , can  VIP, MSH MSH Sleep disturbances, chronic pain, enthesopathy, GI/malabsorption, leaky gut, prolonged illness, resistant Staph, Pituitary/Adrenal axis disruption, Reduced sex hormones, reduced ADH Due to low Leptin activity on Hypothalamus (Leptin levels may be ) VEGF Poor perfusion/cell starvation, Exercise intolerance C4a Hypoperfusion, lactosis, low glutamate/glutamine on MR Spectroscopy Brain fog, HA, myalgias, thermoregulation, Exercise intolerance Actos/low amylose diet (if Leptin >7, but Omega-3’s if Leptin <7), VIP C3a Actos/low amylose diet (if Leptin >7, but Omega-3’s if Leptin <7), VIP Androgens Actos/low amylose diet (if Leptin >7, but Omega-3’s if Leptin <7), DHEA 2) Medication Effects; Cholestyramine, Welchol Absorbs Gut Toxins BEG/Rifampin Kills MARCONS Actos/Low Amylose if Leptin >7 (otherwise Omega-3’s) Lowers MMP9, TNF, PIE-1, Leptin Losartan Lowers TGF β-1
CIRS_Overview.docx