cells 22-7 Immune System Development Immune System Development Fetus can produce immune response (has immunocompetence) After exposure to antigen At three to four months 22-7 Immune System Development Development of Immunocompetence thymus cells migrate to tissues that form T cells Liver and bone marrow produce B cells Four-month fetus produces IgM antibodies 22-7 Immune System Development Before Birth Maternal IgG antibodies Pass through placenta Provide passive immunity to fetus After Birth Mother’s milk provides IgA antibodies While passive immunity is lost 22-7 Immune System Development Normal Resistance Infant produces IgG antibodies through exposure to antigens Antibody, B cell, and T cell levels slowly rise to adult levels About age 12 22-7 Immune System Development Cytokines of the Immune System Chemical messengers involved in cellular immunity Hormones and paracrine-like glycoproteins Examples of cytokines: Interferons Interleukins necrosis factors (TNFs) 22-7 Immune System Development Interleukins
cells 22-7 Immune System Development Immune System Development Fetus can produce immune response (has immunocompetence) After exposure to antigen At three to four months 22-7 Immune System Development Development of Immunocompetence thymus cells migrate to tissues that form T cells Liver and bone marrow produce B cells Four-month fetus produces IgM antibodies 22-7 Immune System Development Before Birth Maternal IgG antibodies Pass through placenta Provide passive immunity to fetus After Birth Mother’s milk provides IgA antibodies While passive immunity is lost 22-7 Immune System Development Normal Resistance Infant produces IgG antibodies through exposure to antigens Antibody, B cell, and T cell levels slowly rise to adult levels About age 12 22-7 Immune System Development Cytokines of the Immune System Chemical messengers involved in cellular immunity Hormones and paracrine-like glycoproteins Examples of cytokines: Interferons Interleukins necrosis factors (TNFs) 22-7 Immune System Development Interleukins
ch_22_lecture_note.docx