No incidence with evidence favoring the intervention group and risk ratio of Are the desirable ○ anticipated effects Probably no 0.41 (0.02, 0.86 95 % CI). Length of stay in the ICU has high certainty ○ large? Uncertain and favors neither intervention or control (mean difference -1.00; 95% CI ● -0.71) Additionally, patients who are started on an antipsychotic for delirium in the ICU often remain on these medications after discharge from the ICU and even after hospital discharge . These are additional harms that cannot be addressed by this current literature. Are the undesirable No ○ anticipated effects Probably no ○ small? Uncertain ● Are the desirable No ○ effects large Probably no ○ relative to Uncertain ● undesirable effects? Resource use No Expense of risperidone is intermediate. Are the resources ○ required small? Probably no ○
incidence with evidence favoring the intervention group and risk ratio of 0.41 (0.02, 0.86 95 % CI). Length of stay in the ICU has high certainty and favors neither intervention or control (mean difference -1.00; 95% CI -0.71) Additionally, patients who are started on an antipsychotic for delirium in the ICU often remain on these medications after discharge from the ICU and even after hospital discharge . These are additional harms that cannot be addressed by this current literature. Are the desirable anticipated effects large? ○ No ○ Probably no ● Uncertain Are the undesirable anticipated effects small? ○ No ○ Probably no ● Uncertain Are the desirable effects large relative to undesirable effects? ○ No ○ Probably no ● Uncertain Resource use Are the resources required small? ○ No ○ Probably no Expense of risperidone is intermediate.
CCM_46_9_2018_06_08_DEVLIN_CCMED-D-18-00069_SDC26.docx