Outcome: Observational Reduction in the data also suggest incidence of that pre- or SIDS postnatal exposure to Evidence tobacco smoke statement and hyperthermia Grade E: There or over wrapping is good evidence may also to suggest that increase the risk this intervention of SIDS. The has a sound evidence for theoretical basis effectiveness of or that work in advice on this area is likely smoking is drawn to have an largely from impact but this observational has not been studies no SRs demonstrated in – or RCTs. Advice trials (this would to avoid apply to exposure interventions for seems to reduce which RCTs the incidence of would be SIDS but the particularly campaigns difficult or included other unethical) advice in addition to avoiding Intervention: tobacco-smoke National exposure, and in campaigns some countries giving advice to the incidence of avoid bed SIDS had started sharing to fall before the campaign Outcome: started. Some Reduction in the national incidence of campaigns have SIDS included advice to avoid Evidence overheating/ statement overwrapping, in Grade E: There addition to is good evidence recommendations to suggest that on other risk this intervention
Observational data also suggest that pre- or postnatal exposure to tobacco smoke and hyperthermia or over wrapping may also increase the risk of SIDS. The evidence for effectiveness of advice on smoking is drawn largely from observational studies – no SRs or RCTs. Advice to avoid exposure seems to reduce the incidence of SIDS but the campaigns included other advice in addition to avoiding tobacco-smoke exposure, and in some countries the incidence of SIDS had started to fall before the campaign started. Some national campaigns have included advice to avoid overheating/ overwrapping, in addition to recommendations on other risk Outcome: Reduction in the incidence of SIDS Evidence statement Grade E: There is good evidence to suggest that this intervention has a sound theoretical basis or that work in this area is likely to have an impact but this has not been demonstrated in trials (this would apply to interventions for which RCTs would be particularly difficult or unethical) Intervention: National campaigns giving advice to avoid bed sharing Outcome: Reduction in the incidence of SIDS Evidence statement Grade E: There is good evidence to suggest that this intervention
CDR%20Research%20Evidence%20Review%20SUID%20report%20FINAL%20091014.docx