Dermal lethal dose (LD50) < 2,000 mg/kg For purposes of demonstrating compliance with this requirement, existing acute toxicity data for each of the product’s present at 0.01% or more in the components may be used. These data are used to undiluted product calculate a weighted average that assumes that the toxicity of the individual is additive. The toxicity values are components adjusted by the weight of the in the product and components summed using the following formula: Where, TP = toxicity of the product wti = the weight fraction of the component TV = the toxicity value for each (LD50) component n = number of components Inhalation toxicity be determined from all components present at 0.01% or more in the when the undiluted product, has a vapor pressure greater than 1 mm Hg at 1 atm component pressure and 20°C. Note: Refer to Annex C for potential alternate thresholds for closed dilution-control systems. Note: Refer to Annex D for potential alternate thresholds for products. powder/solid/nonaqueous liquid 3.4 *Skin and Eye Damage. The shall undiluted product not cause or cause For skin corrosion serious eye damage. purposes of demonstrating compliance with this requirement, data may be evaluated for each of the product’s at components present 0.01% or more in the If these undiluted product. at their concentrations in the components, undiluted product, are not shown to cause or skin corrosion serious eye damage, then the product will not be considered to cause skin corrosion or Results from peer-reviewed studies or serious eye damage. standard in vitro or in vivo testing methods may also be accepted. Testing is not required for any ingredient for which sufficient information exists. Further, a product is considered to cause or to skin corrosion cause if it has a pH less than or equal to 2 serious eye damage or greater than or equal to 11.5, unless data prove otherwise. Note: to Annex C for potential alternate thresholds for closed dilution-control systems.
Dermal lethal dose (LD50) < 2,000 mg/kg For purposes of demonstrating compliance with this requirement, existing acute toxicity data for each of the product’s components present at 0.01% or more in the undiluted product may be used. These data are used to calculate a weighted average that assumes that the toxicity of the individual components is additive. The toxicity values are adjusted by the weight of the components in the product and summed using the following formula: Where, TP = toxicity of the product wti = the weight fraction of the component TV = the toxicity value for each component (LD50) n = number of components Inhalation toxicity be determined from all components present at 0.01% or more in the undiluted product, when the component has a vapor pressure greater than 1 mm Hg at 1 atm pressure and 20°C. Note: Refer to Annex C for potential alternate thresholds for closed dilution-control systems. Note: Refer to Annex D for potential alternate thresholds for powder/solid/nonaqueous liquid products. 3.4 *Skin and Eye Damage. The undiluted product shall not cause skin corrosion or cause serious eye damage. For purposes of demonstrating compliance with this requirement, data may be evaluated for each of the product’s components at present 0.01% or more in the undiluted product. If these components, at their concentrations in the undiluted product, are not shown to cause skin corrosion or serious eye damage, then the product will not be considered to cause skin corrosion or serious eye damage. Results from peer-reviewed studies or standard in vitro or in vivo testing methods may also be accepted. Testing is not required for any ingredient for which sufficient information exists. Further, a product is considered to cause skin corrosion or to cause serious eye damage if it has a pH less than or equal to 2 or greater than or equal to 11.5, unless data prove otherwise. Note: to Annex C for potential alternate thresholds for closed dilution-control systems.
CCL_GS-51_Laundry-Care_Institutional-2017.docx