How large are the resource 1. Can J Hosp Pharm 2012;65(2):103–110. Cost effectiveness favors alpha2 agonists (dex) but costs requirements (costs)? [4] are varied since off patent but still many countries have different costs for dex which makes this challenging Large costs The average cost of the medication DEX Vs. ○ Moderate costs midazolam ($1929.57 Vs. $180.10 per ○ Negligible costs and savings patient). ○ Moderate savings ○ Average costs associated with mechanical Large savings ○ required Resources ventilation ($2939 Vs. $4448) and management of delirium ($2127 Vs. $3012). Varies ○ The overall cost per patient was ($7022 V. Don't know ○ $7680). What is the certainty of the evidence of resource requirements (costs)? of of x Low required resources Certainty evidence Does the cost-effectiveness of the intervention favor the intervention or the comparison? Probably favors the intervention ● Cost effectiveness
Resources required How large are the resource requirements (costs)? ○ Large costs ○ Moderate costs ○ Negligible costs and savings ○ Moderate savings ○ Large savings ○ Varies ○ Don't know 1. Can J Hosp Pharm 2012;65(2):103–110. [4] The average cost of the medication DEX Vs. midazolam ($1929.57 Vs. $180.10 per patient). Average costs associated with mechanical ventilation ($2939 Vs. $4448) and management of delirium ($2127 Vs. $3012). The overall cost per patient was ($7022 V. $7680). Cost effectiveness favors alpha2 agonists (dex) but costs are varied since off patent but still many countries have different costs for dex which makes this challenging Certainty of evidence of required resources What is the certainty of the evidence of resource requirements (costs)? x Low Cost effectiveness Does the cost-effectiveness of the intervention favor the intervention or the comparison? ● Probably favors the intervention
CCM_46_9_2018_06_08_DEVLIN_CCMED-D-18-00069_SDC15.docx