- Reactions that produce 2 asymmetric center will produce isomers depending on the type of stereochemistry - For non-stereospecific the reaction will produce possible configurations all ⇒ - For stereospecific the reaction will only produce products with new bonds on the side syn same ⇒ - For stereospecific the reaction will only produce products with new bonds on the side anti opposite ⇒ Reagents Reaction Example Stereochemistry Example HCl, HBr HI or H2O ROH or with H2SO4 Cl2 Br2 or with CH2Cl2 Cl2 Br2 or with H2O ROH or 1. BH3, THF 2. NaOH(aq), H2O2 H2 D2 or with Pd/C RCO3H aka peroxy acid 1. O3, -78°C 2. (CH3)2S N/A or Zn, CH3CO2H
- Reactions that produce 2 asymmetric center will produce isomers depending on the type of stereochemistry - For non-stereospecific ⇒ the reaction will produce all possible configurations - For stereospecific syn ⇒ the reaction will only produce products with new bonds on the same side - For stereospecific anti ⇒ the reaction will only produce products with new bonds on the opposite side Reagents Reaction Example Stereochemistry Example HCl, HBr or HI H2O or ROH with H2SO4 Cl2 or Br2 with CH2Cl2 Cl2 or Br2 with H2O or ROH 1. BH3, THF 2. NaOH(aq), H2O2 H2 or D2 with Pd/C RCO3H aka peroxy acid 1. O3, -78°C 2. (CH3)2S or Zn, CH3CO2H N/A
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