ICU length of stay Setting: Intensive care units Perspective: Criteria Judgements Research evidence Problem Is there a problem No The evidence for this recommendation comes from 2 RCT's: Devlin 2010 ○ (quetiapine) and Girard 2010 (ziprasidone), including a total of 48 patients in the priority? Probably no ○ intervention groups and 54 in the placebo comparator group. Open label haloperidol Uncertain ○ was used in both of these studies. Probably yes ○ Yes ● Varies ○ Benefits & What is the overall No included studies ○ The relative importance or values of harms of the certainty of this Very low ○ options evidence? Low ● Moderate ○ High ○
ICU length of stay Setting: Intensive care units Perspective: Criteria Judgements Research evidence Problem Is there a problem priority? ○ No ○ Probably no ○ Uncertain ○ Probably yes ● Yes ○ Varies The evidence for this recommendation comes from 2 RCT's: Devlin 2010 (quetiapine) and Girard 2010 (ziprasidone), including a total of 48 patients in the intervention groups and 54 in the placebo comparator group. Open label haloperidol was used in both of these studies. Benefits & harms of the options What is the overall certainty of this evidence? ○ No included studies ○ Very low ● Low ○ Moderate ○ High The relative importance or values of
CCM_46_9_2018_06_08_DEVLIN_CCMED-D-18-00069_SDC26.docx