Quality of 2 SRs did not 1 SR did not All 5 SRs SRs assessed via Jadad SR: With the NOS, SR 2010:xlvii With included report quality report quality assessed study or Cochrane assessed studies as D&B, assessed studies evidence as assessment; 1 assessment; 1 quality using a Collaboration tool. having low-risk bias; as low quality reported developed a developed a variety of tools Other study types used funnel plot for primary SR 2014:xlviii With the custom tool but custom tool (e.g., Cochrane NOS. RCT quality outcome showed no Jadad scale, assessed did not report but did not Collaboration, usually high; others obvious publication studies as scoring 2/5 results; 3 used a report results; Jadad, custom); low to moderate bias & 3/5 (low) tool developed by the other 4 quality was the Cochrane used various generally Collaboration and tools and assessed as risk of bias determined moderate to high generally low studies were generally high quality with low risk of bias Patient From 1 to 5 Generally 3 to 6 months to 8 From post-op course in SR: 6 months SR 2010:xlvii NR years 5 years trial; generally hospital up to 9.1 Primary study: 24 SR 2014:xlviii 34 days months months to 8 years RCT 2012: 15 (± SD 2) months SD=Standard deviation; SR=Systematic review; RCT=randomized controlled trial KEY: AAA=Abdominal aortic aneurysm; BMS=Bare metal stents; D&B=Downs & Black; DES=Drug eluting stents; EVAR=endovascular aneurysm repair; IVC=Inferior vena cava; MA=Meta-analysis; NOS=Newcastle-Ottawa scale; NR=not reported; PDA=Patent ductus
Quality of included evidence as reported 2 SRs did not report quality assessment; 1 developed a custom tool but did not report results; 3 used a tool developed by the Cochrane Collaboration and risk of bias generally low 1 SR did not report quality assessment; 1 developed a custom tool but did not report results; the other 4 used various tools and determined studies were generally high quality with low risk of bias All 5 SRs assessed study quality using a variety of tools (e.g., Cochrane Collaboration, Jadad, custom); quality was generally assessed as moderate to high SRs assessed via Jadad or Cochrane Collaboration tool. Other study types used NOS. RCT quality usually high; others low to moderate SR: With the NOS, assessed studies as having low-risk bias; funnel plot for primary outcome showed no obvious publication bias SR 2010:xlvii With D&B, assessed studies as low quality SR 2014:xlviii With the Jadad scale, assessed studies as scoring 2/5 & 3/5 (low) Patient From 1 to 5 years Generally 3 to 5 years 6 months to 8 generally months From post-op course in hospital up to 9.1 SR: 6 months Primary study: 24 months SR 2010:xlvii NR SR 2014:xlviii 34 days to 8 years RCT 2012: 15 (± SD 2) months SD=Standard deviation; SR=Systematic review; RCT=randomized controlled trial KEY: AAA=Abdominal aortic aneurysm; BMS=Bare metal stents; D&B=Downs & Black; DES=Drug eluting stents; EVAR=endovascular aneurysm repair; IVC=Inferior vena cava; MA=Meta-analysis; NOS=Newcastle-Ottawa scale; NR=not reported; PDA=Patent ductus trial;
consult-draft-clinical-evidence-guidelines-medical-devices.docx