What is the overall certainty of the evidence of No research evidence was effects? identified. Low ● evidence Certainty of Is important uncertainty about or variability in No research evidence was how much people value the main outcomes? identified. Probably no important uncertainty or variability ● Values Does the balance between desirable and undesirable No research evidence was effects favor the intervention or the comparison? identified. Probably favors the intervention ● effects Balance of How are the resource requirements (costs)? older studies showed that The moderate effect on outcomes precludes propofol was more costly, but any effects on costs especially now that these data do not apply now, propofol is off patent. Negligible and savings ● and required Resources
Certainty of evidence What is the overall certainty of the evidence of effects? ● Low No research evidence was identified. Values Is important uncertainty about or variability in how much people value the main outcomes? ● Probably no important uncertainty or variability No research evidence was identified. Balance of effects Does the balance between desirable and undesirable effects favor the intervention or the comparison? ● Probably favors the intervention No research evidence was identified. Resources required How are the resource requirements (costs)? ● Negligible and savings older studies showed that propofol was more costly, but these data do not apply now, and The moderate effect on outcomes precludes any effects on costs especially now that propofol is off patent.
CCM_46_9_2018_06_08_DEVLIN_CCMED-D-18-00069_SDC15.docx