Benefits & No included studies What is the overall ○ harms of the certainty of this Very low The relative importance or values of the ○ options evidence? Low ● Moderate ○ High ○ Is there important Important uncertainty ○ uncertainty about or variability Possibly important how much people ○ value the main uncertainty or variability outcomes? Probably no important ● uncertainty or variability No important ○ uncertainty or variability No undesirable ○ outcomes Are the desirable No ○ anticipated effects Probably no ○ large? Uncertain ● Probably yes ○ Yes ○ Varies ○
Benefits & harms of the options What is the overall certainty of this evidence? ○ No included studies ○ Very low ● Low ○ Moderate ○ High The relative importance or values of the Is there important uncertainty about how much people value the main outcomes? ○ Important uncertainty or variability ○ Possibly important uncertainty or variability ● Probably no important uncertainty or variability ○ No important uncertainty or variability ○ No undesirable outcomes Are the desirable anticipated effects large? ○ No ○ Probably no ● Uncertain ○ Probably yes ○ Yes ○ Varies
CCM_46_9_2018_06_08_DEVLIN_CCMED-D-18-00069_SDC26.docx