Summary of judgements Judgement Problem No Probably no Probably yes Yes Varies Don't know Desirable Effects Trivial Moderate Varies Don't know Undesirable Effects Large Moderate Trivial Varies Don't know Certainty of evidence Very low Low Moderate High No included studies Important Possibly important No important Probably no Values uncertainty or uncertainty or important uncertainty uncertainty or variability variability or variability variability Does not either the Favors the Probably favors the Probably favors the Favors the Balance of effects intervention or the Varies Don't know comparison comparison intervention intervention comparison Negligible costs and Resources required Large costs Moderate Moderate savings Large savings Varies Don't know savings Certainty of evidence Very low Low Moderate High No included studies of required resources Does not favor either Favors the Probably favors the Probably favors the Favors the Cost effectiveness the intervention or the Varies No included studies comparison comparison intervention intervention comparison Equity Reduced Probably reduced Probably no impact Probably increased Increased Varies Don't know Acceptability No Probably no Probably yes Yes Varies Don't know No Probably no Probably yes Varies Don't know Feasibility Yes Conclusions Should propofol vs. a benzodiazepine be used in critically ill ventilated adults (both intubated and non-intubated)?
Summary of judgements Judgement Problem No Probably no Probably yes Yes Varies Don't know Desirable Effects Trivial Moderate Varies Don't know Undesirable Effects Large Moderate Trivial Varies Don't know Certainty of evidence Very low Low Moderate High No included studies Values Important uncertainty or variability Possibly important uncertainty or variability Probably no important uncertainty or variability No important uncertainty or variability Balance of effects Favors the comparison Probably favors the comparison Does not either the intervention or the comparison Probably favors the intervention Favors the intervention Varies Don't know Resources required Large costs Moderate Negligible costs and savings Moderate savings Large savings Varies Don't know Certainty of evidence of required resources Very low Low Moderate High No included studies Cost effectiveness Favors the comparison Probably favors the comparison Does not favor either the intervention or the comparison Probably favors the intervention Favors the intervention Varies No included studies Equity Reduced Probably reduced Probably no impact Probably increased Increased Varies Don't know Acceptability No Probably no Probably yes Yes Varies Don't know Feasibility No Probably no Probably yes Yes Varies Don't know Conclusions Should propofol vs. a benzodiazepine be used in critically ill ventilated adults (both intubated and non-intubated)?
CCM_46_9_2018_06_08_DEVLIN_CCMED-D-18-00069_SDC15.docx