Wide confidence intervals do not exclude harm. Small number of events. Influenza Forest Plots - Rodrigo C, Leonardi-Bee J,Nguyen-Van-Tam J, LimWS.Corticosteroids as adjunctive therapy in the treatment of influenza. Cochrane Database of Systematic Reviews 2016, Issue 3. Art. No.: CD010406. DOI: 10.1002/14651858.CD010406.pub2. Evidence Profile for corticosteroids in Influenza of № Quality assessment Effect patients Quality of Risk of Relative Absolute № Study design studies bias considerations (95% CI) (95% CI) Mortality (assessed with: in-hospital) 4 observational not not strong OR 2.82 3 fewer per 1000 ⨁⨁◯◯ studies serious 1 association (1.61 to 4.92) (from 2 fewer to 5 fewer) LOW 2 CI: Confidence interval; OR: Odds ratio All 4 trials found to be low risk of bias according to Ottawa-Newcastle scale.
Wide confidence intervals do not exclude harm. Small number of events. Influenza Forest Plots - Rodrigo C, Leonardi-Bee J,Nguyen-Van-Tam J, LimWS.Corticosteroids as adjunctive therapy in the treatment of influenza. Cochrane Database of Systematic Reviews 2016, Issue 3. Art. No.: CD010406. DOI: 10.1002/14651858.CD010406.pub2. Evidence Profile for corticosteroids in Influenza Quality assessment № of patients Effect Quality № of studies Study design Risk of bias considerations Relative (95% CI) Absolute (95% CI) Mortality (assessed with: in-hospital) 4 observational studies not serious 1 not 2 strong association OR 2.82 (1.61 to 4.92) 3 fewer per 1000 (from 2 fewer to 5 fewer) ⨁⨁◯◯ LOW CI: Confidence interval; OR: Odds ratio All 4 trials found to be low risk of bias according to Ottawa-Newcastle scale.
CCM_46_1_2017_10_04_PASTORES_CCMED-D-17-01855_SDC2.docx