Acceptability No Is the option ○ acceptable to key Probably no ○ stakeholders? Uncertain ○ Probably yes ● Yes ○ Varies ○ Feasibility Is the option No ○ feasible to Probably no ○ Uncertain implement? ○ Probably yes ● Yes ○ Varies ○ Recommendation Should an an alpha-2 agonist (e.g., dexmedetomidine) vs. no such strategy be used in critically ill adults WITH delirium? Balance of Undesirable Undesirable consequences The balance between Desirable consequences Desirable consequences consequences consequences desirable and undesirable clearly probably outweigh probably outweigh clearly outweigh desirable outweigh
Acceptability Is the option acceptable to key stakeholders? ○ No ○ Probably no ○ Uncertain ● Probably yes ○ Yes ○ Varies Feasibility Is the option feasible to implement? ○ No ○ Probably no ○ Uncertain ● Probably yes ○ Yes ○ Varies Recommendation Should an an alpha-2 agonist (e.g., dexmedetomidine) vs. no such strategy be used in critically ill adults WITH delirium? Balance of consequences Undesirable consequences clearly outweigh desirable Undesirable consequences probably outweigh The balance between desirable and undesirable Desirable consequences probably outweigh Desirable consequences clearly outweigh
CCM_46_9_2018_06_08_DEVLIN_CCMED-D-18-00069_SDC26.docx