Bacterial Infections Morphology Clinical Laboratory Disease Pathogenesis Manifestation Findings Microscopic Macroscopic Tuberculous Spreaded Mixture of Subarachnoid Generalized Lumbar puncture through Lymphocytes space contains Headache Elevated Infection of heamatogenous Gelatinous Malaise protein Plasma cells CNS and usually Mental Glucose may Fibrinous exudate Macrophages comes about confusion be This exudate most Florid show from Vomiting Moderately often finds at the granulomas disseminated reduced base of brain, Often presented with pulmonary Normal obliterating caseating necrosis tuberculosis Cisterns and giant cells Mimicking the Encasing cranial morphology of nerves pulmonary May present with tuberculosis descrete white Obliterative granules scattered endarteritis of artery over the running through Leptomeninges subarachnoid space Tuberculoma may Same appearance have a bigger for Tuberculoma lesion Complications Hydrocephalus Exudate may organize and form arachnoid fibrosis which may occlude the arachnoid granulation leading to communicating hydrocephalus Obliterative Endarteritis Artery may become occluded during healing and subsequently leads to cerebral infarction
Bacterial Infections Disease Pathogenesis Morphology Clinical Manifestation Laboratory Findings Microscopic Macroscopic Tuberculous Infection of CNS Spreaded through heamatogenous and usually comes about from disseminated pulmonary tuberculosis Mixture of Lymphocytes Plasma cells Macrophages Florid show granulomas Often presented with caseating necrosis and giant cells Mimicking the morphology of pulmonary tuberculosis Obliterative endarteritis of artery running through subarachnoid space Same appearance for Tuberculoma Subarachnoid space contains Gelatinous Fibrinous exudate This exudate most often finds at the base of brain, obliterating Cisterns Encasing cranial nerves May present with descrete white granules scattered over the Leptomeninges Tuberculoma may have a bigger lesion Generalized Headache Malaise Mental confusion Vomiting Lumbar puncture Elevated protein Glucose may be Moderately reduced Normal Complications Hydrocephalus Exudate may organize and form arachnoid fibrosis which may occlude the arachnoid granulation leading to communicating hydrocephalus Obliterative Endarteritis Artery may become occluded during healing and subsequently leads to cerebral infarction
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