years or sooner if the patient develops symptoms suggestive of thyroid dysfunction, thyromegaly, an abnormal growth rate, or an unexplained glycemic variation. E Consider screening with Additional reference - Citation #33 (Chapter Elfström P1, Sundström type 1 diabetes for proposal to upgrade 11) J, Ludvigsson JF. celiac disease by recommendation to C. Systematic review with measuring either tissue Meta-analysis/ meta-analysis: transglutaminase or systematic review of Citation #34 (Chapter associations between deamidated gliadin studies with at least 100 11) coeliac disease and type antibodies, with individuals with type 1 1 diabetes. documentation of diabetes screened for Aliment Pharmacol normal total serum IgA coeliac disease: More Citation #35 (Chapter Ther. 2014 levels, soon after the than one in twenty 11) Nov;40(10):1123-32. diagnosis of diabetes. E patients with type 1 diabetes have coeliac disease. Citation #36 (Chapter 11) Citation #37 (Chapter 11) Citation #38 (Chapter 11) Consider screening in See who have a first-degree relative with celiac disease, growth failure, weight loss, failure to gain weight, diarrhea, flatulence, abdominal pain, or signs of malabsorption or in children with frequent unexplained hypoglycemia or deterioration in glycemic control. E with biopsy-confirmed See above celiac disease should be
years or sooner if the patient develops symptoms suggestive of thyroid dysfunction, thyromegaly, an abnormal growth rate, or an unexplained glycemic variation. E Consider screening with type 1 diabetes for celiac disease by measuring either tissue transglutaminase or deamidated gliadin antibodies, with documentation of normal total serum IgA levels, soon after the diagnosis of diabetes. E Additional reference - proposal to upgrade recommendation to C. Meta-analysis/ systematic review of studies with at least 100 individuals with type 1 diabetes screened for coeliac disease: More than one in twenty patients with type 1 diabetes have coeliac disease. Citation #33 (Chapter 11) Citation #34 (Chapter 11) Citation #35 (Chapter 11) Citation #36 (Chapter 11) Citation #37 (Chapter 11) Citation #38 (Chapter 11) Elfström P1, Sundström J, Ludvigsson JF. Systematic review with meta-analysis: associations between coeliac disease and type 1 diabetes. Aliment Pharmacol Ther. 2014 Nov;40(10):1123-32. Consider screening in who have a first-degree relative with celiac disease, growth failure, weight loss, failure to gain weight, diarrhea, flatulence, abdominal pain, or signs of malabsorption or in children with frequent unexplained hypoglycemia or deterioration in glycemic control. E See with biopsy-confirmed celiac disease should be See above
2017_evidence_table_master_0.docx