properties of colloids, solubilization gels structure, properties and – applications. Micromatics: Particle size and size distribution average particle size, – particle size distribution, number and weight distributions, particle number; methods for determining particle size optical microscopy, sieving, sedimentation, – particle volume measurement, particle shape and surface area, methods for determining surface area absorption methods, air permeability methods; derived – properties of powders porosity, packing arrangements, densities bulkiness, flow – properties. UNIT V Rheology: Newtonian systems laws of flow, kinetic viscosity, effect of – – temperature. Non newtonian systems plastic, pseudoplastic dilatant flow, – thixotropy measutement of thixotropy, thixotropy in formulation. – Determination of rheologic properties choice of viscometer, capillary, falling – sphere, cup and bob, and cone and plate viscometers. Psychorheology. Applications to pharmacy. Coarse dispersions, emulsions and semisolids. Interfacial properties of suspended particles p settling in suspensions theory of sedimentaion, effect – of Brownian movement, sedimentation of flocculated particles, sedimentation parameters. Formulation of suspensions wetting of particles, controlled – flocculation, theological considerations, preparation of suspensions. Emulsions types, pharmaceutical applications, theories, physical stability, preservation, – and theological properties. Semisolidsgels. TEXT BOOKS: Physical Pharmacy Martin, A. & others. – REFERENCE BOOKS Tutorial Pharmacy Cooper & Gunn. –
properties of colloids, solubilization gels – structure, properties and applications. Micromatics: Particle size and size distribution – average particle size, particle size distribution, number and weight distributions, particle number; methods for determining particle size – optical microscopy, sieving, sedimentation, particle volume measurement, particle shape and surface area, methods for determining surface area – absorption methods, air permeability methods; derived properties of powders – porosity, packing arrangements, densities bulkiness, flow properties. UNIT – V Rheology: Newtonian systems – laws of flow, kinetic viscosity, effect of temperature. Non newtonian systems – plastic, pseudoplastic dilatant flow, thixotropy – measutement of thixotropy, thixotropy in formulation. Determination of rheologic properties – choice of viscometer, capillary, falling sphere, cup and bob, and cone and plate viscometers. Psychorheology. Applications to pharmacy. Coarse dispersions, emulsions and semisolids. Interfacial properties of suspended particles p settling in suspensions – theory of sedimentaion, effect of Brownian movement, sedimentation of flocculated particles, sedimentation parameters. Formulation of suspensions – wetting of particles, controlled flocculation, theological considerations, preparation of suspensions. Emulsions – types, pharmaceutical applications, theories, physical stability, preservation, and theological properties. Semisolidsgels. TEXT BOOKS: Physical Pharmacy – Martin, A. & others. REFERENCE BOOKS Tutorial Pharmacy – Cooper & Gunn.
bpholdsyllabus.docx