hemizygous classical genetics hormonal wild-type molecular genetics cell-autonomous variant true breeding lines sexual locus monohybrid cross genotype Punnett Square sexually dimorphic phenotype test cross gynandromorphy dominant tester mosaic recessive sex-linked chimera complete dominance dosage compensation G + E = P incomplete (semi) X-linked genes penetrance dominance autosomal genes expressivity co-dominance reciprocal cross sampling effects ABO blood group Z-linked chi-square test χ2 haplosufficiency hermaphrodites haploinsufficiency parthenogenesis 3.1 What is the maximum number of e) Based on the information provided alleles for a locus in a normal in question 1, can you tell which, if gamete of a diploid species? either, of the alleles is wild-type? Wirey hair (W) is dominant to 3.2 smooth hair (w) in dogs. 3.3 An important part of Mendel’s a) If you cross a homozygous, experiments was the use of dog with a smooth-haired dog, homozygous lines as parents for his what will be the genotype and crosses. How did he know they were phenotype of the F1 generation? homozygous, and why was the use of the lines important? If two dogs from the F1 generation b) mated, what would be the most likely 3.4 Does segregation of alleles ratio of hair into daughter cells happen during phenotypes among their progeny? mitosis, meiosis, or both? c) When two wirey-haired Ww dogs actually mated, they had alitter of 3.5 If your blood type is B, what are three puppies, which all had smooth the possible genotypes of your hair. How do you explain this parents at the locus that controls the observation? ABO blood types? d) Someone left a wirey-haired dog on 3.6 In the table below, match the your doorstep. Without extracting mouse hair color phenotypes with the DNA, term from the list that best explains what be the easiest way to the observed phenotype, given the determine the genotype of this dog? genotypes shown. In this case, the allele symbols do not imply anything about the dominance relationships
hemizygous wild-type variant locus genotype phenotype dominant recessive complete dominance incomplete (semi) dominance co-dominance ABO blood group haplosufficiency haploinsufficiency classical genetics molecular genetics true breeding lines monohybrid cross Punnett Square test cross tester sex-linked dosage compensation X-linked genes autosomal genes reciprocal cross Z-linked hermaphrodites parthenogenesis hormonal cell-autonomous sexual sexually dimorphic gynandromorphy mosaic chimera G + E = P penetrance expressivity sampling effects chi-square χ2 test 3.1 What is the maximum number of alleles for a locus in a normal gamete of a diploid species? 3.2 Wirey hair (W) is dominant to smooth hair (w) in dogs. a) If you cross a homozygous, dog with a smooth-haired dog, what will be the genotype and phenotype of the F1 generation? b) If two dogs from the F1 generation mated, what would be the most likely ratio of hair phenotypes among their progeny? c) When two wirey-haired Ww dogs actually mated, they had alitter of three puppies, which all had smooth hair. How do you explain this observation? d) Someone left a wirey-haired dog on your doorstep. Without extracting DNA, what be the easiest way to determine the genotype of this dog? e) Based on the information provided in question 1, can you tell which, if either, of the alleles is wild-type? 3.3 An important part of Mendel’s experiments was the use of homozygous lines as parents for his crosses. How did he know they were homozygous, and why was the use of the lines important? 3.4 Does segregation of alleles into daughter cells happen during mitosis, meiosis, or both? 3.5 If your blood type is B, what are the possible genotypes of your parents at the locus that controls the ABO blood types? 3.6 In the table below, match the mouse hair color phenotypes with the term from the list that best explains the observed phenotype, given the genotypes shown. In this case, the allele symbols do not imply anything about the dominance relationships
zChap03_140901.docx