Jovanovic-Peterson L, Peterson CM, Reed GF, et al. Maternal postprandial glucose levels and infant weight: the Diabetes in Early Pregnancy Study. The National Institute of Child Health and Human Development--Diabetes in Early Pregnancy Study. Am J Obstet Gynecol. 1991; PMID: 1986596 Due to increased red N/A Citations #3, #4 #12 Mosca A, Paleari R, cell turnover, A1C (Chapter 12) Dalfra MG, DiCianni G is lower in normal There is an additional et al. Reference pregnancy than in reference with a larger intervals for normal nonpregnant sample size (445 non hemoglobin A1c in women. The A1C target diabetic pregnant pregnant women: data in pregnancy is 6–6.5% women) who were from an Italian (42–48 mmol/mol); <6% tested at between 15 multicenter study. (42 mmol/mol) may be and 36 weeks and Citation #12 is a study Clinical Chemistry 2006; optimal if this can be compared to 384 of 100 pregnant women 52(6): 1138-1143. achieved without controls. It without diabetes and significant provides standards for supports the assertion hypoglycemia, but the various gestational that A1c is lower in target may be relaxed intervals. early and later to <7% (53 mmol/mol) pregnancy than in the if necessary to prevent non-pregnant state. hypoglycemia. B Diabetes Care in the Hospital Consider performing an New evidence that Pasquel FJ, A1C on all patients with supports use of A1C R, Anzola L et diabetes or al. Predictive Value of hyperglycemia admitted But still a C Admission Hemoglobin to the hospital if not recommendation A1c on Inpatient performed in the prior 3 Glycemic Control and months. C Response to Insulin Therapy in Medicine and Surgery Patients With Type 2 Diabetes. Diabetes Care 2015 Dec; 38(12): e202-e203
Jovanovic-Peterson L, Peterson CM, Reed GF, et al. Maternal postprandial glucose levels and infant weight: the Diabetes in Early Pregnancy Study. The National Institute of Child Health and Human Development--Diabetes in Early Pregnancy Study. Am J Obstet Gynecol. 1991; PMID: 1986596 Due to increased red cell turnover, A1C is lower in normal pregnancy than in normal nonpregnant women. The A1C target in pregnancy is 6–6.5% (42–48 mmol/mol); <6% (42 mmol/mol) may be optimal if this can be achieved without significant hypoglycemia, but the target may be relaxed to <7% (53 mmol/mol) if necessary to prevent hypoglycemia. B N/A There is an additional reference with a larger sample size (445 non diabetic pregnant women) who were tested at between 15 and 36 weeks and compared to 384 controls. It provides standards for various gestational intervals. Citations #3, #4 #12 (Chapter 12) Citation #12 is a study of 100 pregnant women without diabetes and supports the assertion that A1c is lower in early and later pregnancy than in the non-pregnant state. Mosca A, Paleari R, Dalfra MG, DiCianni G et al. Reference intervals for hemoglobin A1c in pregnant women: data from an Italian multicenter study. Clinical Chemistry 2006; 52(6): 1138-1143. Diabetes Care in the Hospital Consider performing an A1C on all patients with diabetes or hyperglycemia admitted to the hospital if not performed in the prior 3 months. C New evidence that supports use of A1C But still a C recommendation Pasquel FJ, R, Anzola L et al. Predictive Value of Admission Hemoglobin A1c on Inpatient Glycemic Control and Response to Insulin Therapy in Medicine and Surgery Patients With Type 2 Diabetes. Diabetes Care 2015 Dec; 38(12): e202-e203
2017_evidence_table_master_0.docx