Situation Suggested antibiotics If allergic to penicillin Comments Oral treatment Clindamycin Treat for about 10 to 14 Non-purulent MILD: Skin/Soft Tissue Penicillin VK Or Vancomycin days or until signs of Infection Amoxicillin inflammation have resolved (i.e. Cephalexin erysipelas, cellulitis, necrotizing Cloxacillin infections) Clindamycin IV MODERATE: treatment Penicillin G Cefazolin or ceftriaxone Clindamycin SEVERE: Surgical vs. empiric treatment Surgical Vancomycin + Piperacilin/tazobactam Purulent MILD: Clindamycin Skin/Soft Tissue Incision and drainage Or Infection Vancomycin (i.e.iImpetigo, Or ecthyma, MODERATE: furuncle, carbuncle, Linezolid Incision & drainage abscess) and culture & sensitivity , plus empiric or defined treatment Doxycycline Cephalexin Cloxacillin SEVERE: Incision & drainage and culture & sensitivity, plus empiric or defined treatment Vancomycin Linezolid Cefazolin Clindamycin Table 6: Per Dr. Stephan Landis Guelph 2015 Venous Dermatitis: Symptoms, Prevention and Treatment
Situation Suggested antibiotics If allergic to penicillin Comments Non-purulent Skin/Soft Tissue Infection (i.e. erysipelas, cellulitis, necrotizing infections) MILD: Oral treatment Penicillin VK Amoxicillin Cephalexin Cloxacillin Clindamycin MODERATE: IV treatment Penicillin G Cefazolin or ceftriaxone Clindamycin SEVERE: Surgical vs. empiric treatment Surgical Vancomycin + Piperacilin/tazobactam Clindamycin Or Vancomycin Treat for about 10 to 14 days or until signs of inflammation have resolved Purulent Skin/Soft Tissue Infection (i.e.iImpetigo, ecthyma, furuncle, carbuncle, abscess) MILD: Incision and drainage MODERATE: Incision & drainage and culture & sensitivity , plus empiric or defined treatment Doxycycline Cephalexin Cloxacillin SEVERE: Incision & drainage and culture & sensitivity, plus empiric or defined treatment Vancomycin Linezolid Cefazolin Clindamycin Clindamycin Or Vancomycin Or Linezolid Table 6: Per Dr. Stephan Landis Guelph 2015 Venous Dermatitis: Symptoms, Prevention and Treatment
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