Soft tissue necrosis, including Staphylococcal TSS is defined by : necrotising fasciitis or myositis; or Fever: temperature ≥38.9C gangrene. Hypotension: systolic blood pressure mmHg ≤90 A definite case is an illness fulfilling criteria IA Diffuse macular rash with subsequent and II (A and B). desquamation one or two weeks after onset (including palms and soles) A probable case is an illness fulfilling criteria IB Multisystem involvement (three or more and II (A and B) where no other aetiology is of the following): identified. Hepatic: bilirubin or (Working Group on Severe Streptococcal aminotransferase times ≥2 Infections 1993). normal Haematologic: platelet count Staphylococcal TSS is defined by: x 109/L ≤100 Renal: blood urea nitrogen or Fever: temperature ≥38.9°C; serum creatinine level times ≥2 normal Hypotension: systolic blood pressure Mucous membranes: vaginal, mmHg in adults or in the 5th ≤90 oropharyngeal or conjunctival percentile for age in children; hyperaemia Diffuse macular rash with subsequent Gastrointestinal: vomiting or desquamation one to two weeks after diarrhoea at illness onset (including palms and soles); Muscular: severe myalgia or Multisystem involvement (three or serum creatinine phosphokinase more of the following): level times upper limit ≥2 Central nervous system: Hepatic: bilirubin or aminotransferase disorientation or alteration in times normal; ≥2 consciousness without focal neurological signs and in the absence of fever or hypotension.
Soft tissue necrosis, including necrotising fasciitis or myositis; or gangrene. A definite case is an illness fulfilling criteria IA and II (A and B). A probable case is an illness fulfilling criteria IB and II (A and B) where no other aetiology is identified. (Working Group on Severe Streptococcal Infections 1993). Staphylococcal TSS is defined by: Fever: temperature ≥38.9°C; Hypotension: systolic blood pressure ≤90 mmHg in adults or in the 5th percentile for age in children; Diffuse macular rash with subsequent desquamation one to two weeks after onset (including palms and soles); Multisystem involvement (three or more of the following): Hepatic: bilirubin or aminotransferase ≥2 times normal; Staphylococcal TSS is defined by : Fever: temperature ≥38.9C Hypotension: systolic blood pressure ≤90 mmHg Diffuse macular rash with subsequent desquamation one or two weeks after onset (including palms and soles) Multisystem involvement (three or more of the following): Hepatic: bilirubin or aminotransferase ≥2 times normal Haematologic: platelet count ≤100 x 109/L Renal: blood urea nitrogen or serum creatinine level ≥2 times normal Mucous membranes: vaginal, oropharyngeal or conjunctival hyperaemia Gastrointestinal: vomiting or diarrhoea at illness Muscular: severe myalgia or serum creatinine phosphokinase level ≥2 times upper limit Central nervous system: disorientation or alteration in consciousness without focal neurological signs and in the absence of fever or hypotension.
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