the Orange County Groundwater Replenishment Scheme (Daugherty et al 2005) and the Singapore NEWater Scheme24 has not detected estrone or 17α-ethynylestradiol, 17β-estradiol. Table A8a Recommended drinking water guideline for pharmaceuticals with agricultural and veterinary applications ADI (ug/kg/day)b DWG Margin of (μg/L) Pharmaceutical Maximum exposure (DWG concentrations ÷ highest detected (μg/L)a concentration) Antibiotics Amoxycillin 0.02 0.43 1.5 75 c Anhydro-erythromycin A 0.92 5d 17.5 10 11 Azithromycin 0.072 3.9 54 d 10 Cephalexin 0.09 35 390 g 30 105 Chlorotetracycline 0.28 375 e e Doxycycline 0.03 3 10.5 350 f 6.2 Enrofloxacin 0.015 22 1500 f Erythromycin 1.7 5 17.5 10 f 1,000 Lincomycin 0.015 3500 230,000 g 10 Monensin 0.08 35 440 g 0.43 Penicillin G 0.03 1.5 50 c 0.43 Penicillin V 0.21 1.5 7.1 c 10h Sulfadimethoxine 0.06 35 580 10h Sulfamethazine 0.68 35 52 10h Sulfamethiazole 0.13 35 269 10h Sulfamethoxazole 1.9 35 18 30 105 Terramycin (oxytetracycline) 0.66 160 e e 30 105 Tetracycline 0.11 950 e e 20 Trimethoprim 0.35 70 200 g 300 Tylosin 1.1 1050 950 g Nonsteroidal anti-inflammatory drugs (NSAIDs) 8.3f Aspirin 2.1 29 14 0.5 Diclofenac 0.81 1.8 2.2 f 150f Dipyrone 7.5 525 70 Ketoprofen 0.38 1 3.5 9.2 g Tolfenamic acid 1.6 5 17.5 11 g blockers β-andrenergic 0.1i Carazolol 0.12 0.35 2.9 24
the Orange County Groundwater Replenishment Scheme (Daugherty et al 2005) and the Singapore NEWater Scheme24 has not detected 17α-ethynylestradiol, estrone or 17β-estradiol. Table A8a Recommended drinking water guideline for pharmaceuticals with agricultural and veterinary applications Pharmaceutical Maximum concentrations detected (μg/L)a ADI (ug/kg/day)b DWG (μg/L) Margin of exposure (DWG ÷ highest concentration) Antibiotics Amoxycillin 0.02 0.43 c 1.5 75 Anhydro-erythromycin A 0.92 5d 17.5 10 Azithromycin 0.072 11 d 3.9 54 Cephalexin 0.09 10 g 35 390 Chlorotetracycline 0.28 30 e 105 e 375 Doxycycline 0.03 3 f 10.5 350 Enrofloxacin 0.015 6.2 f 22 1500 Erythromycin 1.7 5 f 17.5 10 Lincomycin 0.015 1,000 g 3500 230,000 Monensin 0.08 10 g 35 440 Penicillin G 0.03 0.43 c 1.5 50 Penicillin V 0.21 0.43 c 1.5 7.1 Sulfadimethoxine 0.06 10h 35 580 Sulfamethazine 0.68 10h 35 52 Sulfamethiazole 0.13 10h 35 269 Sulfamethoxazole 1.9 10h 35 18 Terramycin (oxytetracycline) 0.66 30 e 105 e 160 Tetracycline 0.11 30 e 105 e 950 Trimethoprim 0.35 20 g 70 200 Tylosin 1.1 300 g 1050 950 Nonsteroidal anti-inflammatory drugs (NSAIDs) Aspirin 2.1 8.3f 29 14 Diclofenac 0.81 0.5 f 1.8 2.2 Dipyrone 7.5 150f 525 70 Ketoprofen 0.38 1 g 3.5 9.2 Tolfenamic acid 1.6 5 g 17.5 11 β-andrenergic blockers Carazolol 0.12 0.1i 0.35 2.9 24
water-recycling-guidelines-augmentation-drinking-22.docx