Early use in streptococcal TSS. Qualifying criteria have been defined in line Diagnosis of streptococcal or Qualifying Criteria with existing criteria - requiring confirmed or Probable or confirmed diagnosis of staphylococcal TSS in accordance with suspected diagnosis and failure to achieve streptococcal TSS. criteria listed above, preferably with rapid improvement with supportive AND measures. Failure to achieve rapid improvement with isolation of organism; supportive measures. AND Staphylococcal TSS where rapid improvement is not obtained with fluid resuscitation, inotropes, Failure to achieve rapid improvement surgery, antibiotic therapy and other supportive with fluid resuscitation, inotropes, measures. surgery, antibiotic therapy and other supportive measures. Probable or confirmed diagnosis of staphylococcal TSS. AND Failure to achieve rapid improvement with supportive measures. N/A Early use in streptococcal TSS. Review Criteria Given that TSS requires one-off treatment, Review is not mandated for this indication there is no review with automatic patient however the following criteria may be useful in outcome data collection. Outcome measures assessing the effectiveness of therapy. have been developed including: One month survival Outcome data to be measured Patient and recovered One month survival Patient still in ICU Documented clinical response to Ig Patient rehabilitating therapy. Patient deceased Staphylococcal TSS where rapid improvement is not obtained with fluid resuscitation, inotropes
Qualifying Criteria Diagnosis of streptococcal or staphylococcal TSS in accordance with criteria listed above, preferably with isolation of organism; AND Failure to achieve rapid improvement with fluid resuscitation, inotropes, surgery, antibiotic therapy and other supportive measures. Early use in streptococcal TSS. Probable or confirmed diagnosis of streptococcal TSS. AND Failure to achieve rapid improvement with supportive measures. Staphylococcal TSS where rapid improvement is not obtained with fluid resuscitation, inotropes, surgery, antibiotic therapy and other supportive measures. Probable or confirmed diagnosis of staphylococcal TSS. AND Failure to achieve rapid improvement with supportive measures. Qualifying criteria have been defined in line with existing criteria - requiring confirmed or suspected diagnosis and failure to achieve rapid improvement with supportive measures. Review Criteria N/A Early use in streptococcal TSS. Review is not mandated for this indication however the following criteria may be useful in assessing the effectiveness of therapy. Outcome data to be measured One month survival Documented clinical response to Ig therapy. Staphylococcal TSS where rapid improvement is not obtained with fluid resuscitation, inotropes Given that TSS requires one-off treatment, there is no review with automatic patient outcome data collection. Outcome measures have been developed including: One month survival Patient and recovered Patient still in ICU Patient rehabilitating Patient deceased
toxic-shock-syndrome-tss.DOCX