Pertussis Reporting Both confirmed cases and probable cases should be notified. case Confirmed A case requires either: Laboratory definitive evidence OR Laboratory suggestive evidence AND clinical evidence Probable case A probable case requires clinical evidence AND epidemiological evidence Laboratory evidence Isolation of Bordetella pertussis OR Detection of by nucleic acid testing B. pertussis OR Seroconversion in paired sera for using whole cell or specific antigen(s) in B. pertussis B. pertussis the absence of recent pertussis vaccination Laboratory suggestive evidence In the absence of recent vaccination Significant change (increase or decrease) in antibody level (IgG, IgA) to whole cell or B. pertussis specific antigen(s) B. pertussis OR Single high IgG and/or IgA titre to Pertussis Toxin (PT) OR Single high IgA titre to Whole Cell antigen. B. pertussis Clinical evidence A coughing illness lasting two or more weeks OR Paroxysms of coughing OR inspiratory whoop OR post-tussive vomiting. Epidemiological evidence An epidemiological link is established when there is: Contact between two people involving a plausible mode of transmission at a time when: one of them is likely to be infectious (from the catarrhal stage, approximately one week before, to three weeks after onset of cough) AND
Pertussis Reporting Both confirmed cases and probable cases should be case A case requires either: Laboratory definitive evidence OR Laboratory suggestive evidence AND clinical evidence Probable case A probable case requires clinical evidence AND epidemiological evidence Laboratory evidence Isolation of Bordetella pertussis OR Detection of B. pertussis by nucleic acid testing OR Seroconversion in paired sera for B. pertussis using whole cell or specific B. pertussis antigen(s) in the absence of recent pertussis vaccination Laboratory suggestive evidence In the absence of recent vaccination Significant change (increase or decrease) in antibody level (IgG, IgA) to B. pertussis whole cell or B. pertussis specific antigen(s) OR Single high IgG and/or IgA titre to Pertussis Toxin (PT) OR Single high IgA titre to Whole Cell B. pertussis antigen. Clinical evidence A coughing illness lasting two or more weeks OR Paroxysms of coughing OR inspiratory whoop OR post-tussive vomiting. Epidemiological evidence An epidemiological link is established when there is: Contact between two people involving a plausible mode of transmission at a time when: one of them is likely to be infectious (from the catarrhal stage, approximately one week before, to three weeks after onset of cough) AND Confirmed notified.
w-consolidated-case-definitions.docx