Patients with Klinefelter Syndrome are also observed to develop various types of cancers like testicular cancer, non-Hodgkin’s lymphoma, brain tumor and various tumors of digestive system. Breast cancer is not very common in men but 4% of all men having breast cancer are Klinefelter Syndrome patients (Hasel et al., 1995). Treatment includes hormone therapy to treat hypergonadism and speech therapy helps young Klinefelter Syndrome patients for speech delay. Psychiatric problems are also observed in Klinefelter Syndrome patients for which counseling and medication appears helpful. 13.2.3.1.2.1.2. 47, XYY SYNDROME It is the most common trisomy in male population. Almost 1 out of 1000 male is born with an extra y chromosome (Table 13-II). For long it was considered to be related to socially aggressive behavior but no solid evidence has been reported so far. Many studies done on criminals have reported higher number of XYY karyotype persons. The IQ level of XYY is usually below average due to which these patients experience problems in academic life but with extra help it can be overcome. Many of XYY have been known to secure professional degrees. Poor social life is very prominent among XYY people and due to which their marital life has been observed to suffer badly. Usually patients are fertile and most of them are not diagnosed throughout their lives. These people experience delayed motor development or defects in motor coordination in younger age. Speech delay is also observed and patients undergo speech therapy. Usually these patients are taller in height. No specific physical or facial abnormality has been observed so far (Leggett et al., 2010). 13.2.3.1.2.2. TRISOMIES IN FEMALE (XXX, XXXX, XXXXX META FEMALE)
Patients with Klinefelter Syndrome are also observed to develop various types of cancers like testicular cancer, non-Hodgkin’s lymphoma, brain tumor and various tumors of digestive system. Breast cancer is not very common in men but 4% of all men having breast cancer are Klinefelter Syndrome patients (Hasel et al., 1995). Treatment includes hormone therapy to treat hypergonadism and speech therapy helps young Klinefelter Syndrome patients for speech delay. Psychiatric problems are also observed in Klinefelter Syndrome patients for which counseling and medication appears helpful. 13.2.3.1.2.1.2. 47, XYY SYNDROME It is the most common trisomy in male population. Almost 1 out of 1000 male is born with an extra y chromosome (Table 13-II). For long it was considered to be related to socially aggressive behavior but no solid evidence has been reported so far. Many studies done on criminals have reported higher number of XYY karyotype persons. The IQ level of XYY is usually below average due to which these patients experience problems in academic life but with extra help it can be overcome. Many of XYY have been known to secure professional degrees. Poor social life is very prominent among XYY people and due to which their marital life has been observed to suffer badly. Usually patients are fertile and most of them are not diagnosed throughout their lives. These people experience delayed motor development or defects in motor coordination in younger age. Speech delay is also observed and patients undergo speech therapy. Usually these patients are taller in height. No specific physical or facial abnormality has been observed so far (Leggett et al., 2010). 13.2.3.1.2.2. TRISOMIES IN FEMALE (XXX, XXXX, XXXXX META FEMALE)
Variation%20in%20Chromosome%20Number.docx