medications (p<0.05). 3) Sense of well being (pre-RF 2.0±0.3 vs. post-RF 3.8±0.5, p<0.01) and function in daily life 2.3±0.4 vs. post-RF 3.6±0.6, p<0.01) improved after ablation, but did not change significantly in pts treated w/ drugs. Ablation: 20 pts To define an b)13 pts w/ N/A Recurrent IART Overall 38 N/A N/A No statistical analysis Entrainment E Single (47 approach for ablation refractory to meds. (81%) of 47 mapping 2001 center, circuits) mapping and guided by Late post repair of IARTs combined w/ (199) ablation, entrainment CHD successfully 3D combining and 3D ablated. In f/u trial anatomy, ranging from mapping activation mapping 3-46 mo: allows sequence a)16 (80%) of delineation of ablation data and 20 pts complex of multi entrainment remains free circuits IART mapping. of recurrence and critical circuits a) 7 pts w/ b)Success isthmuses as in adults ablation similar in both targets for w/ CHD guided by groups but RFA as a guided entrainment fluoroscopy satisfactory by mapping only time treatment decreased modality for from 60 +/- 30 IARTs related mapping to 24 +/- 9 to CHD. w/ and min/procedure w/o 3D w/ addition of 3D mapping mapping Delle To IV diltiazem N/A Critically ill pts w/ N/A Sustained Bradycardia or Uncontrolled 1° endpoint: NS The study
medications (p<0.05). 3) Sense of well being (pre-RF 2.0±0.3 vs. post-RF 3.8±0.5, p<0.01) and function in daily life 2.3±0.4 vs. post-RF 3.6±0.6, p<0.01) improved after ablation, but did not change significantly in pts treated w/ drugs. E 2001 (199) Ablation: Single center, trial ablation of multi IART circuits in adults w/ CHD guided by mapping w/ and w/o 3D mapping 20 pts (47 circuits) To define an approach for mapping and ablation, combining anatomy, activation sequence data and entrainment mapping. a) 7 pts w/ ablation guided by entrainment mapping only b)13 pts w/ ablation guided by entrainment and 3D mapping N/A Recurrent IART refractory to meds. Late post repair of CHD Overall 38 (81%) of 47 IARTs successfully ablated. In f/u ranging from 3-46 mo: a)16 (80%) of 20 pts remains free of recurrence b)Success similar in both groups but fluoroscopy time decreased from 60 +/- 30 to 24 +/- 9 min/procedure w/ addition of 3D mapping N/A N/A No statistical analysis Entrainment mapping combined w/ 3D mapping allows delineation of complex circuits and critical isthmuses as targets for RFA as a satisfactory treatment modality for IARTs related to CHD. Delle To IV diltiazem N/A Critically ill pts w/ N/A Sustained Bradycardia or Uncontrolled 1° endpoint: NS The study
2015_SVT_Evidence_Tables_Data_Supplement.docx