Report comments 45 The final result should be able to distinguish active infection from resolved infection and acute infection using a combination of antibody, antigen and NAAT tests. Following an initial (first sample) positive result it is best practice to request a repeat sample. Investigation of hepatitis C infection by HCV antibody testing confirmed by NAAT 2nd Assay 3rd Assay Interpretative comments Notes 1st Assay Optional if needed HCV Ab HCV NAAT HCV Ab 1 Unreactive Not tested Not tested HCV antibody not detected. HCV antibody reactive HCV antibody detected on the basis that the presence of HCV RNA allows one to infer with confidence that the HCV IgG reaction HCV RNA detected is a true positive. Evidence of active HCV Advise referral to an appropriate specialist for further treatment. infection. Please ensure hepatitis A and B immunity status is known and Consider requesting HCV vaccination given if needed. Reactive or genotyping and other BBV 2 RNA Detected Not tested Equivocal testing unless already performed. Refer to hepatitis service. Hepatitis A and B vaccine recommended if appropriate”.
Report comments 45 The final result should be able to distinguish active infection from resolved infection and acute infection using a combination of antibody, antigen and NAAT tests. Following an initial (first sample) positive result it is best practice to request a repeat sample. Investigation of hepatitis C infection by HCV antibody testing confirmed by NAAT 1st Assay 2nd Assay 3rd Assay Optional if needed Interpretative comments Notes HCV Ab HCV NAAT HCV Ab 1 Unreactive Not tested Not tested HCV antibody not detected. 2 Reactive or Equivocal RNA Detected Not tested HCV antibody reactive HCV RNA detected Evidence of active HCV infection. Consider requesting HCV genotyping and other BBV testing unless already performed. Refer to hepatitis service. Hepatitis A and B vaccine recommended if appropriate”. HCV antibody detected on the basis that the presence of HCV RNA allows one to infer with confidence that the HCV IgG reaction is a true positive. Advise referral to an appropriate specialist for further treatment. Please ensure hepatitis A and B immunity status is known and vaccination given if needed.
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