intracellular antibodies: identification of hnRNP-K as a potential target for metastasis. Proc 2007; 104: 8983–8988. Natl Acad Sci USA 71. Chigurupati S, Arumugam TV, Son TG, Lathia JD, Jameel S, Mughal MR et al. Involvement of notch signaling in wound healing. 2007; 2: e1167. PLoS One 72. U, Hauge C, Frank SR, Jensen CJ, Duda K, Nielsen JV et al. RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells. Mol Cell 2009; 35: 511–522. 73. Zhang S, Cao Z, Tian H, Shen G, Ma Y, Xie H et al. SKLB1002, a novel potent inhibitor of VEGF receptor 2 signaling, inhibits angiogenesis and tumor growth in vivo. Clin Cancer 2011; 17: 4439–4450. Res 74. Wu CS, Wu PH, Fang AH, Lan CC. inhibits the enhancing effects of transforming growth factor (TGF)-beta1 on collagen expression and TGF-beta/ Smad signalling in keloid fibroblasts: implication for new therapeutic approach, 2012; 167: 532–541. B J Dermatol 75. Mendoza-Naranjo A, Cormie OP, Serrano AE, Hu R, O’Neill S, Wang CM et al. Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. 2012; 7: PLoS One e37374. 76. Xu W, Jong Hong S, Jia S, Zhao Y, Galiano RD, Mustoe TA. Application of a
intracellular antibodies: identification of hnRNP-K as a potential target for metastasis. Proc Natl Acad Sci USA 2007; 104: 8983–8988. 71. Chigurupati S, Arumugam TV, Son TG, Lathia JD, Jameel S, Mughal MR et al. Involvement of notch signaling in wound healing. PLoS One 2007; 2: e1167. 72. U, Hauge C, Frank SR, Jensen CJ, Duda K, Nielsen JV et al. RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells. Mol Cell 2009; 35: 511–522. 73. Zhang S, Cao Z, Tian H, Shen G, Ma Y, Xie H et al. SKLB1002, a novel potent inhibitor of VEGF receptor 2 signaling, inhibits angiogenesis and tumor growth in vivo. Clin Cancer Res 2011; 17: 4439–4450. 74. Wu CS, Wu PH, Fang AH, Lan CC. inhibits the enhancing effects of transforming growth factor (TGF)-beta1 on collagen expression and TGF-beta/ Smad signalling in keloid fibroblasts: implication for new therapeutic approach, B J Dermatol 2012; 167: 532–541. 75. Mendoza-Naranjo A, Cormie OP, Serrano AE, Hu R, O’Neill S, Wang CM et al. Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. PLoS One 2012; 7: e37374. 76. Xu W, Jong Hong S, Jia S, Zhao Y, Galiano RD, Mustoe TA. Application of a
Wound_models_Revised_review_06_12_16_AB.docx