OJECTIVE - II 2.1. CYCLOPHOSPHAMIDE INDUCED BIOCHEMICAL CHANGES IN 15 DAY OLD CHICK – EMBRYO Table 2.1 represents the biochemical parameters in chick amniotic fluid in controls and CP treated embryos. CP treatment was given on the 15th day of incubation and biochemical analysis was done after 24hrs of treatment. Significant increase (p<0.001) in the levels of glucose, uric acid, creatinine, inorganic phosphorous levels were observed with 100 µg, 200 µg and 300 µg of CP treatment, where as CP, 200 µg caused no significant increase in urea which showed an increased trend (p<0.001) with 300 µg compared with control. Protein levels were significantly increased with 100 µg (p<0.05) and with 200 and 300 µg (p<0.001) of CP treatment. Ascorbic acid, calcium and cholesterol levels were significantly decreased (p<0.001) in a dose dependent manner with CP treatment in AF.
OJECTIVE - II 2.1. CYCLOPHOSPHAMIDE INDUCED BIOCHEMICAL CHANGES IN 15 DAY – OLD CHICK EMBRYO Table 2.1 represents the biochemical parameters in chick amniotic fluid in controls and CP treated embryos. CP treatment was given on the 15th day of incubation and biochemical analysis was done after 24hrs of treatment. Significant increase (p<0.001) in the levels of glucose, uric acid, creatinine, inorganic phosphorous levels were observed with 100 µg, 200 µg and 300 µg of CP treatment, where as CP, 200 µg caused no significant increase in urea which showed an increased trend (p<0.001) with 300 µg compared with control. Protein levels were significantly increased with 100 µg (p<0.05) and with 200 and 300 µg (p<0.001) of CP treatment. Ascorbic acid, calcium and cholesterol levels were significantly decreased (p<0.001) in a dose dependent manner with CP treatment in AF.
UGCMRPFINALREPORTPEAPCODCE.docx