Wasniewska et al 2004 Italy 13.9 (5 21) 8 5 (62.5 %) 0/0 – N = 40 MAS = McCune Albright Syndrome. TCMAS = Testicular cancer in males with McCune Albright Syndrome TML = testicular microlithiasis One male with MAS was reported with an embryonal cell tumour, and five years later with a seminoma in the contralateral testis. a There was no information on TML in this case. Table 3: Characteristics of studies evaluating TML in Cryptorchidism. Author Year Country Mean age N = C N = TML and C N = (range) (Prevalence) TCC/ TCC with TML Cooper et al 2014 USA 11 (1 18) 9 9 (100 %) 10/3 – N = 3370 Chiang et al 2012 Singapore NR (5 15) 12 12 (100%) 0/0 – N = 31 Dutra et al 2011 Brazil 7.5 (1 - 5) 127 5 (3.9 %) 0/0 N = 1504 Yee et al N 2011 Korea 19.1 (0 87) 310 7 (2.3%) NR – = 1439 Goede et al 2010 Netherlands 12.5 (3 29) 501 14 (2.8%) 0/0 – N = 501 Negri et al 2008 37 (20 62) 232 23 (9.9 %) NR – N = 2172 Kosan et al 2007 Turkey 28.3 (NR) 8 2 (25 %) NR N = 197 Konstantinos et al 2006 Greece 37 (15 76) 36 2 (5.5 %) 0/0 – N = 391 Patel et al 2005 USA 19.6 (18 - 29) 112 8 (7.1 %) 0/0 N = 112 C = cryptorchidism. NR=not reported. TCC = testicular cancer in males with cryptorchidism TML = testicular microlithiasis Table 4: Characteristics of studies evaluating TML and male infertility.
Wasniewska et al N = 40 2004 Italy 13.9 (5 – 21) 8 5 (62.5 %) 0/0 MAS = McCune Albright Syndrome. TCMAS = Testicular cancer in males with McCune Albright Syndrome TML = testicular microlithiasis a One male with MAS was reported with an embryonal cell tumour, and five years later with a seminoma in the contralateral testis. There was no information on TML in this case. Table 3: Characteristics of studies evaluating TML in Cryptorchidism. Author Year Country Mean age (range) N = C N = TML and C (Prevalence) N = TCC/ TCC with TML Cooper et al N = 3370 2014 USA 11 (1 – 18) 9 9 (100 %) 10/3 Chiang et al N = 31 2012 Singapore NR (5 – 15) 12 12 (100%) 0/0 Dutra et al N = 1504 2011 Brazil 7.5 (1 - 5) 127 5 (3.9 %) 0/0 Yee et al N = 1439 2011 Korea 19.1 (0 – 87) 310 7 (2.3%) NR Goede et al N = 501 2010 Netherlands 12.5 (3 – 29) 501 14 (2.8%) 0/0 Negri et al N = 2172 2008 37 (20 – 62) 232 23 (9.9 %) NR Kosan et al N = 197 2007 Turkey 28.3 (NR) 8 2 (25 %) NR Konstantinos et al N = 391 2006 Greece 37 (15 – 76) 36 2 (5.5 %) 0/0 Patel et al N = 112 2005 USA 19.6 (18 - 29) 112 8 (7.1 %) 0/0 C = cryptorchidism. NR=not reported. TCC = testicular cancer in males with cryptorchidism TML = testicular microlithiasis Table 4: Characteristics of studies evaluating TML and male infertility.
UROL_D_15_01157_R4.docx