Investigation of hepatitis C infection by antibody testing confirmed by antigen 1st Assay 2nd Assay 3rd assay 4th assay Interpretative comments Notes HCV Ab HCV Ag HCV Ab HCV NAAT 7 Unreactive Not tested Not tested Not tested HCV antibody not detected. Consistent with active HCV infection. Advise referral to an appropriate specialist for further assessment/treatment. Reactive or Consider requesting HCV 8 Reactive Not tested Not tested Equivocal genotyping and recommend other BBV testing unless already preformed. Refer to hepatitis service. Hepatitis A and B vaccine recommended if appropriate. Consider reporting initial HCV Ab reactivity according to local Reactive or No evidence of active HCV 9 Unreactive Unreactive Not tested policy. Equivocal infection Consider reporting initial HCV Ab reactivity according to local Reactive or Not No evidence of active HCV 10 Equivocal Unreactive policy. Equivocal detected infection Consistent with active HCV infection. Advise referral to Reactive or 11 Equivocal Unreactive Detected an appropriate specialist for Equivocal further assessment/treatment.
Investigation of hepatitis C infection by antibody testing confirmed by antigen 1st Assay HCV Ab 2nd Assay HCV Ag 3rd assay HCV Ab 4th assay HCV NAAT Interpretative comments Notes 7 Unreactive Not tested Not tested Not tested HCV antibody not detected. 8 Reactive or Equivocal Reactive Not tested Not tested Consistent with active HCV infection. Advise referral to an appropriate specialist for further assessment/treatment. Consider requesting HCV genotyping and recommend other BBV testing unless already preformed. Refer to hepatitis service. Hepatitis A and B vaccine recommended if appropriate. 9 Reactive or Equivocal Unreactive Unreactive Not tested No evidence of active HCV infection Consider reporting initial HCV Ab reactivity according to local policy. 10 Reactive or Equivocal Equivocal Unreactive Not detected No evidence of active HCV infection Consider reporting initial HCV Ab reactivity according to local policy. 11 Reactive or Equivocal Equivocal Unreactive Detected Consistent with active HCV infection. Advise referral to an appropriate specialist for further assessment/treatment.
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