Xiong ADDIN EN.CITE β-crosslaps of type I Genetic risk score of 5 -1.45 (-3.17, 0.27) 0.10 collagen containing β 2016 Chinese 1,667 1.8% SUA-related SNPs cross-linked Ctelopeptide (ng/L) Xiong ADDIN EN.CITE Genetic risk score of 5 0.76 (-0.63, 2.15) 0.28 β 2016 Chinese 1,667 1.8% 25(OH)D (ng/mL) SUA-related SNPs Neurocognitive disorders ADDIN EN.CITE Genetic risk score of 8 1.05 (0.70, 3.00) 0.31 2014 Spain 343 Dementia in PD NA OR SUA-related SNPs NO ADDIN EN.CITE Simon ADDIN EN.CITE Genetic risk score of 3 1.16 (1.00, 1.35) 0.06 2014 USA 808 (2)* PD progression NA HR SNPs in SCL2A9 (discordance in direction and statistical significance) Overall P>0.05 12 SNPs in SCL2A9 1.06 (0.90, 1.24) 0.51 rs16890979 Gao97 2013 American 1,699 NA OR Parkinson’s disease 0.99 (0.85, 1.16) 0.91 rs13129697
Xiong ADDIN EN.CITE 2016 Chinese 1,667 β-crosslaps of type I collagen containing cross-linked Ctelopeptide (ng/L) Genetic risk score of 5 SUA-related SNPs 1.8% β -1.45 (-3.17, 0.27) 0.10 Xiong ADDIN EN.CITE 2016 Chinese 1,667 25(OH)D (ng/mL) Genetic risk score of 5 SUA-related SNPs 1.8% β 0.76 (-0.63, 2.15) 0.28 Neurocognitive disorders ADDIN EN.CITE 2014 Spain 343 Dementia in PD Genetic risk score of 8 SUA-related SNPs NA OR 1.05 (0.70, 3.00) 0.31 NO ADDIN EN.CITE (discordance in direction and statistical significance) Simon ADDIN EN.CITE 2014 USA 808 (2)* PD progression Genetic risk score of 3 SNPs in SCL2A9 NA HR 1.16 (1.00, 1.35) 0.06 Gao97 2013 American 1,699 Parkinson’s disease 12 SNPs in SCL2A9 NA OR Overall P>0.05 rs16890979 1.06 (0.90, 1.24) 0.51 rs13129697 0.99 (0.85, 1.16) 0.91
Supplementary%20material_v7%20-%20Final-2.docx