Parallel To determine 43 adults (47% male, Whole diet Compliance and Groups Significant Designed to Saltzman 2001 whether w 19-30y in younger provided, weight dietary intake by generally well decrease in allow weight loss diet group and 64-78 in loss diet +/- 45g provided diet. matched. Similar cholesterol and comparison with oats would older group). BMI oats per day. Weight loss in weight loss LDL-C. between older have addition Not selected for Quaker quick oats accordance with between groups. and younger benefits on lipid status (mean incorporated into predictions also increase in ages, and body blood pressure values normal). wide range of indicated weight and lipid foods and were compliance. Blood classifications, concentration consumed at lipids measured but data not compared to every meal. 2 enzymatically, reported weight loss week weight LDL-C calculated. alone. stabilisation ANCOVA and followed by 6 analysis. week weight loss phase with or without oats. Sundberg 2008 To determine 44 adults (30% male) Intervention Compliance by Groups well Significant Equal numbers the effects of with elevated LDL-C consisted of daily recording of matched for diet decreases in total of adverse soluble fibre in a (>3.2 mmol/L) between 60g/day barley test food intake during the cholesterol and events (gastric commercial the ages of 20 and 75 fibre flakes and returned interventions, LDL-C. problems) barley product years (mean 63.4 (3.06g/day packages (>97%). but no data recorded for on risk markers years) Placebo Dietary intake with regarding usual each for CHD, namely group received 3 d food records. diet prior to intervention. LDL-C, HDL-C 60g/day of wheat Blood analysed intervention. and total flakes with according to Higher cholesterol cellulose. No standard concentration of 2x 4 wk procedures at insoluble dietary intervention with 4 Centre for fibre recorded wk washout. Laboratory during the Medicine, placebo Uppsala., treatment. Sweden. Differences analysed with paired t-tests.
Saltzman 2001 Parallel To determine whether w weight loss diet with oats would have addition benefits on blood pressure and lipid concentration compared to weight loss alone. 43 adults (47% male, 19-30y in younger group and 64-78 in older group). BMI Not selected for lipid status (mean values normal). Whole diet provided, weight loss diet +/- 45g oats per day. Quaker quick oats incorporated into wide range of foods and were consumed at every meal. 2 week weight stabilisation followed by 6 week weight loss phase with or without oats. Compliance and dietary intake by provided diet. Weight loss in accordance with predictions also indicated compliance. Blood lipids measured enzymatically, LDL-C calculated. ANCOVA and analysis. Groups generally well matched. Similar weight loss between groups. Significant decrease in cholesterol and LDL-C. increase in Designed to allow comparison between older and younger ages, and body weight classifications, but data not reported Sundberg 2008 To determine the effects of soluble fibre in a commercial barley product on risk markers for CHD, namely LDL-C, HDL-C and total cholesterol 44 adults (30% male) with elevated LDL-C (>3.2 mmol/L) between the ages of 20 and 75 years (mean 63.4 years) Intervention consisted of 60g/day barley fibre flakes (3.06g/day Placebo group received 60g/day of wheat flakes with cellulose. No 2x 4 wk intervention with 4 wk washout. Compliance by daily recording of test food intake and returned packages (>97%). Dietary intake with 3 d food records. Blood analysed according to standard procedures at Centre for Laboratory Medicine, Uppsala., Sweden. Differences analysed with paired t-tests. Groups well matched for diet during the interventions, but no data regarding usual diet prior to intervention. Higher concentration of insoluble dietary fibre recorded during the placebo treatment. Significant decreases in total cholesterol and LDL-C. Equal numbers of adverse events (gastric problems) recorded for each intervention.
SR%20beta-glucan%20cholesterol%20-%20Master%20version.docx