Meropenem 0.25 1 0.03 0.12 0.03 0.25 - – – – Amoxicillin/clavulanic - 0.12 0.5 0.03 0.12 - – – Chloramphenicol - 2 16 2 8 - – – Vancomycin - 0.5 2 0.12 0.5 - – – Penicillin - 0.25 2 0.25 1 - – – Ceftriaxone 8 64 1 8 0.03 0.12 - – – – * strain under investigation Beta-lactam/beta-lactam inhibitor combinations Antibiotic E. coli ATCC E. coli ATCC (mm) 35218 (MIC) Ampicillin 10 6 - µg Amoxi-clav 17 22 4 16 – – 20/10 µg 24 30 0.5 2 – – 100/10 µg Detection of resistance mechanisms QC ESBL K. pneumoniae ATCC 700603: ESBL positive D-test S. aureus ATCC BAA-976: D-test negative S. aureus ATCC BAA-977: D-test positive MRSA S. aureus ATCC 43300: cefoxitin 30 µg disk diameter 21 mm ≤ Frequency of quality control testing
Meropenem 0.25 – 1 0.03 – 0.12 0.03 – 0.25 - Amoxicillin/clavulanic - 0.12 – 0.5 0.03 – 0.12 - Chloramphenicol - 2 – 16 2 – 8 - Vancomycin - 0.5 – 2 0.12 – 0.5 - Penicillin - 0.25 – 2 0.25 – 1 - Ceftriaxone 8 – 64 1 – 8 0.03 – 0.12 - * strain under investigation Beta-lactam/beta-lactam inhibitor combinations Antibiotic E. coli ATCC (mm) E. coli ATCC 35218 (MIC) Ampicillin 10 µg 6 - Amoxi-clav 20/10 µg 17 – 22 4 – 16 100/10 µg 24 – 30 0.5 – 2 Detection of resistance mechanisms QC ESBL K. pneumoniae ATCC 700603: ESBL positive D-test S. aureus ATCC BAA-976: D-test negative S. aureus ATCC BAA-977: D-test positive MRSA S. aureus ATCC 43300: cefoxitin 30 µg disk diameter ≤ 21 mm Frequency of quality control testing
TLM_PRO_099_Appendix%202_v1.0_Quality%20control.docx