TABLE OF CONTENTS SUMMARY 3 CONCLUSIONS AND REGULATORY OBLIGATIONS 3 ASSESSMENT DETAILS 5 1. APPLICANT AND NOTIFICATION DETAILS 5 2. IDENTITY OF CHEMICAL 5 3. COMPOSITION 5 4. PHYSICAL AND CHEMICAL PROPERTIES 6 5. INTRODUCTION AND USE INFORMATION 6 6. HEALTH IMPLICATIONS 8 6.1. Exposure Assessment 8 6.1.1. Occupational Exposure 8 6.1.2. Public Exposure 9 6.2. Human Health Effects Assessment 9 6.3. Human Health Risk Characterisation 10 6.3.1. Occupational Health and Safety 10 6.3.2. Public Health 10 7. ENVIRONMENTAL IMPLICATIONS 10 7.1. Environmental Exposure & Fate Assessment 10 7.1.1. Environmental Exposure 10 7.1.2. Environmental Fate 12 7.1.3. Predicted Environmental Concentration (PEC) 12 7.2. Environmental Effects Assessment 12 7.2.1. Predicted No-Effect Concentration 12 7.3. Environmental Risk Assessment 12 Appendix B: Toxicological Investigations 13 B.1. Acute toxicity oral 13 – B.2. toxicity dermal 13 – B.3. Irritation skin 14 – B.4. Irritation eye 14 – B.5. Repeat dose toxicity 15 B.6. Genotoxicity bacteria 16 – B.7. Genotoxicity 17 – in vitro B.8. Genotoxicity 18 in vitro – Appendix C: Environmental Fate and Ecotoxicological Investigations 19 C.1. Environmental Fate 19 C.1.1. Ready biodegradability 19 C.2. Ecotoxicological Investigations 19 C.2.1. Acute toxicity to fish 19 C.2.2. Acute toxicity to aquatic invertebrates 20 C.2.3. Algal growth inhibition test 21 BIBLIOGRAPHY 22
TABLE OF CONTENTS SUMMARY 3 CONCLUSIONS AND REGULATORY OBLIGATIONS 3 ASSESSMENT DETAILS 5 1. APPLICANT AND NOTIFICATION DETAILS 5 2. IDENTITY OF CHEMICAL 5 3. COMPOSITION 5 4. PHYSICAL AND CHEMICAL PROPERTIES 6 5. INTRODUCTION AND USE INFORMATION 6 6. HEALTH IMPLICATIONS 8 6.1. Exposure Assessment 8 6.1.1. Occupational Exposure 8 6.1.2. Public Exposure 9 6.2. Human Health Effects Assessment 9 6.3. Human Health Risk Characterisation 10 6.3.1. Occupational Health and Safety 10 6.3.2. Public Health 10 7. ENVIRONMENTAL IMPLICATIONS 10 7.1. Environmental Exposure & Fate Assessment 10 7.1.1. Environmental Exposure 10 7.1.2. Environmental Fate 12 7.1.3. Predicted Environmental Concentration (PEC) 12 7.2. Environmental Effects Assessment 12 7.2.1. Predicted No-Effect Concentration 12 7.3. Environmental Risk Assessment 12 Appendix B: Toxicological Investigations 13 B.1. Acute toxicity – oral 13 B.2. toxicity – dermal 13 B.3. Irritation – skin 14 B.4. Irritation – eye 14 B.5. Repeat dose toxicity 15 B.6. Genotoxicity – bacteria 16 B.7. Genotoxicity – in vitro 17 B.8. Genotoxicity – in vitro 18 Appendix C: Environmental Fate and Ecotoxicological Investigations 19 C.1. Environmental Fate 19 C.1.1. Ready biodegradability 19 C.2. Ecotoxicological Investigations 19 C.2.1. Acute toxicity to fish 19 C.2.2. Acute toxicity to aquatic invertebrates 20 C.2.3. Algal growth inhibition test 21 BIBLIOGRAPHY 22
STD-1502-FR-Final.DOCX