QALY: stroke in Tan Tanny et al. (2013). Hours of Acute Ischemic Stroke. Stroke. 44:2269-2274. Average disability weight (0.20) based on WHO. Impairment is for one year. WHO (2013). WHO methods and data sources for global burden of disease estimates 2000-2011. Average cost of intervention based on casemix funding for 2 cranial procedures IHPA NWAU calculator for acute activity 2016-17. (first procedure is the craniectomy to remove part of the skull and the second Intervention Service cost: Ho et al. (2011). Cost-Effectiveness of Decompressive Craniectomy as a procedure is the cranioplasty to repair the skull 2-3 months later). Average of costs -$42,294 Lifesaving Rescue Procedure for Patients With Severe Traumatic Brain B02A, B02B, B02C = $42,294 per patient. Comparable to Western Injury. Australian study by Ho et al. 2011, ~USD $28,000. SAFE Trial (2004) – The SAFE study: saline vs. albumin for fluid resuscitation in the critically ill Context Fluid resuscitation, (the administration of intravenous fluids to maintain or increase intravascular volume), is a common intervention, used for around 35% of patients in the ICU. There has been enduring controversy as to the impact of the choice of resuscitation fluid on outcomes. patients’ The SAFE study compared patient outcomes when 4% albumin or 0.9% sodium chloride (normal saline) is used for intravascular fluid resuscitation in ICU. The SAFE study found that using 4% albumin and normal saline results in equivalent 28-day all-cause mortality, as well as similar use of mechanical ventilation and renal therapy, and similar length of stays.
QALY: stroke in Tan Tanny et al. (2013). Average disability weight (0.20) based on WHO. Impairment is for one year. Hours of Acute Ischemic Stroke. Stroke. 44:2269-2274. WHO (2013). WHO methods and data sources for global burden of disease estimates 2000-2011. Intervention costs Service cost: -$42,294 Average cost of intervention based on casemix funding for 2 cranial procedures (first procedure is the craniectomy to remove part of the skull and the second procedure is the cranioplasty to repair the skull 2-3 months later). Average of B02A, B02B, B02C = $42,294 per patient. Comparable to Western Australian study by Ho et al. 2011, ~USD $28,000. IHPA NWAU calculator for acute activity 2016-17. Ho et al. (2011). Cost-Effectiveness of Decompressive Craniectomy as a Lifesaving Rescue Procedure for Patients With Severe Traumatic Brain Injury. SAFE Trial (2004) – The SAFE study: saline vs. albumin for fluid resuscitation in the critically ill Context Fluid resuscitation, (the administration of intravenous fluids to maintain or increase intravascular volume), is a common intervention, used for around 35% of patients in the ICU. There has been enduring controversy as to the impact of the choice of resuscitation fluid on patients’ outcomes. The SAFE study compared patient outcomes when 4% albumin or 0.9% sodium chloride (normal saline) is used for intravascular fluid resuscitation in ICU. The SAFE study found that using 4% albumin and normal saline results in equivalent 28-day all-cause mortality, as well as similar use of mechanical ventilation and renal therapy, and similar length of stays.
Supplementary-Appendix-B-Economic-evaluation-of-investigator-initiated-clinical-trials-conducted-by-networks.docx