To test the effect 10 healthy females Whole diet Compliance not Minimised by Significant No side effects Li 2003 of barley intake (mean age 20.4). provided, in test reported but all cross-over decrease in total of intervention. on blood lipids Cholesterol status phase 30% of meals were design. cholesterol and and glucose in unspecified but carbohydrates provided. Blood Saturated fat LDL-C. No healthy young baseline value replaced with lipids measured intake not change in HDL-C. Japanese indicates normal barley as using commercial reported, but women. cholesterol wholegrain (45% kits, LDL-C total fat intake concentration. barley bran). calculated. similar. 2x 4wk RMANOVA and intervention with analysis. 4wk washout. Parallel To test whether 79 All subjects Compliance Barley bran Significant Barley oil Lupton 1994 adding barley hypercholesterolaemic consumed NCEP unclear. Dietary group had decrease in stratum of bran or subjects (45% male). step 1 diet. One intake by 3d significant cholesterol, not considered barley oil to a 53 subjects in 2 group consumed dietary records. decreases in HDL-C, apoA further. NCEP diet relevant strata of trial. 30g of barley bran Blood lipids energy, and apoB. enhances flour (70% fibre) measured cholesterol and provided as a enzymatically, fat intake, difference in TG. supplement. LDL-C calculated. whereas control Control group ANOVA and t-test group only consumed 20g of analysis. reduced total fat cellulose. 30d intake. intervention. Blood cholesterol concentration tended to be higher in barley compared to control group.
Li 2003 To test the effect of barley intake on blood lipids and glucose in healthy young Japanese women. 10 healthy females (mean age 20.4). Cholesterol status unspecified but baseline value indicates normal cholesterol concentration. Whole diet provided, in test phase 30% of carbohydrates replaced with barley as wholegrain (45% barley bran). 2x 4wk intervention with 4wk washout. Compliance not reported but all meals were provided. Blood lipids measured using commercial kits, LDL-C calculated. RMANOVA and analysis. Minimised by cross-over design. Saturated fat intake not reported, but total fat intake similar. Significant decrease in total cholesterol and LDL-C. No change in HDL-C. No side effects of intervention. Lupton 1994 Parallel To test whether adding barley bran or barley oil to a NCEP diet enhances 79 hypercholesterolaemic subjects (45% male). 53 subjects in 2 relevant strata of trial. All subjects consumed NCEP step 1 diet. One group consumed 30g of barley bran flour (70% fibre) provided as a supplement. Control group consumed 20g of cellulose. 30d intervention. Compliance unclear. Dietary intake by 3d dietary records. Blood lipids measured enzymatically, LDL-C calculated. ANOVA and t-test analysis. Barley bran group had significant decreases in energy, cholesterol and fat intake, whereas control group only reduced total fat intake. Blood cholesterol concentration tended to be higher in barley compared to control group. Significant decrease in cholesterol, HDL-C, apoA and apoB. difference in TG. Barley oil stratum of not considered further.
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