TABLE OF CONTENTS FULL PUBLIC REPORT 3 1. APPLICANT AND NOTIFICATION DETAILS 3 2. IDENTITY OF CHEMICAL 3 3. COMPOSITION 4 4. INTRODUCTION AND USE INFORMATION 4 5. PROCESS AND RELEASE INFORMATION 4 5.1. Distribution, transport and storage 4 5.2. Operation description 4 5.3. Occupational exposure 4 5.4. Release 6 5.5. Disposal 7 5.6. Public exposure 7 6. PHYSICAL AND CHEMICAL PROPERTIES 7 7. TOXICOLOGICAL INVESTIGATIONS 11 7.1. Acute toxicity oral 11 – 7.2. Acute toxicity dermal 11 – 7.4. Irritation skin 11 – 7.5. Irritation eye 13 – 7.6. Skin sensitisation 13 7.7. Repeat dose toxicity 14 7.8. Genotoxicity bacteria 17 – 7.9. Genotoxicity in vitro 18 – 8. ENVIRONMENT 19 8.1. Environmental fate 19 8.1.1. Ready biodegradability 19 8.1.2. Bioaccumulation 19 8.2. Ecotoxicological investigations 20 8.2.1. Acute toxicity to fish 20 8.2.2. Acute/chronic toxicity to aquatic invertebrates 20 8.2.3. Algal growth inhibition test 21 8.2.4. Inhibition of microbial activity 22 9. RISK ASSESSMENT 22 9.1. Environment 22 9.1.1. Environment exposure assessment 22 – 9.1.2. Environment effects assessment 23 – 9.1.3. Environment risk characterisation 23 – 9.2. Human health 23 9.2.1. Occupational health and safety exposure assessment 23 – 9.2.2. Public health exposure assessment 23 – 9.2.3. Human health effects assessment 23 – 9.2.4. Occupational health and safety risk characterisation 23 – 9.2.5. Public health risk characterisation 24 – 10. CONCLUSIONS ASSESSMENT LEVEL OF CONCERN FOR THE ENVIRONMENT AND – HUMANS 24 10.1. Hazard classification 24 10.2. Environmental risk assessment 24 10.3. health risk assessment 24 10.3.1. Occupational health and safety 24 10.3.2. Public health 24 11. MATERIAL SAFETY DATA SHEET 24 11.1. Material Safety Data Sheet 24 11.2. 25 12. RECOMMENDATIONS 25 12.1. Secondary notification 25 13. BIBLIOGRAPHY 25
TABLE OF CONTENTS FULL PUBLIC REPORT 3 1. APPLICANT AND NOTIFICATION DETAILS 3 2. IDENTITY OF CHEMICAL 3 3. COMPOSITION 4 4. INTRODUCTION AND USE INFORMATION 4 5. PROCESS AND RELEASE INFORMATION 4 5.1. Distribution, transport and storage 4 5.2. Operation description 4 5.3. Occupational exposure 4 5.4. Release 6 5.5. Disposal 7 5.6. Public exposure 7 6. PHYSICAL AND CHEMICAL PROPERTIES 7 7. TOXICOLOGICAL INVESTIGATIONS 11 7.1. Acute toxicity – oral 11 7.2. Acute toxicity – dermal 11 7.4. Irritation – skin 11 7.5. Irritation – eye 13 7.6. Skin sensitisation 13 7.7. Repeat dose toxicity 14 7.8. Genotoxicity – bacteria 17 7.9. Genotoxicity – in vitro 18 8. ENVIRONMENT 19 8.1. Environmental fate 19 8.1.1. Ready biodegradability 19 8.1.2. Bioaccumulation 19 8.2. Ecotoxicological investigations 20 8.2.1. Acute toxicity to fish 20 8.2.2. Acute/chronic toxicity to aquatic invertebrates 20 8.2.3. Algal growth inhibition test 21 8.2.4. Inhibition of microbial activity 22 9. RISK ASSESSMENT 22 9.1. Environment 22 9.1.1. Environment – exposure assessment 22 9.1.2. Environment – effects assessment 23 9.1.3. Environment – risk characterisation 23 9.2. Human health 23 9.2.1. Occupational health and safety – exposure assessment 23 9.2.2. Public health – exposure assessment 23 9.2.3. Human health – effects assessment 23 9.2.4. Occupational health and safety – risk characterisation 23 9.2.5. Public health – risk characterisation 24 10. CONCLUSIONS – ASSESSMENT LEVEL OF CONCERN FOR THE ENVIRONMENT AND HUMANS 24 10.1. Hazard classification 24 10.2. Environmental risk assessment 24 10.3. health risk assessment 24 10.3.1. Occupational health and safety 24 10.3.2. Public health 24 11. MATERIAL SAFETY DATA SHEET 24 11.1. Material Safety Data Sheet 24 11.2. 25 12. RECOMMENDATIONS 25 12.1. Secondary notification 25 13. BIBLIOGRAPHY 25
STD1171FR.docx