TABLE OF CONTENTS FULL PUBLIC REPORT 4 1. APPLICANT AND NOTIFICATION DETAILS 4 2. IDENTITY OF CHEMICAL 4 3. COMPOSITION 5 4. INTRODUCTION AND USE INFORMATION 5 5. PROCESS AND RELEASE INFORMATION 5 5.1. Distribution, transport and storage 5 5.2. Operation description 5 5.3. Occupational exposure 6 Exposure Details 6 5.4. Release 7 5.5. Disposal 7 5.6. Public exposure 7 6. PHYSICAL AND CHEMICAL PROPERTIES 8 7. TOXICOLOGICAL INVESTIGATIONS 10 7.1. Acute toxicity oral 10 – 7.2. toxicity dermal 11 – 7.3. Acute toxicity inhalation 11 – 7.4. Irritation skin 11 – 7.5. Irritation eye 12 – 7.6. Skin sensitisation 13 7.7. Repeat dose toxicity 14 7.8. Genotoxicity bacteria 15 – 7.9. Genotoxicity in 16 – 7.10. Genotoxicity in vivo 17 – 8. ENVIRONMENT 18 8.1. Environmental fate 18 8.1.1. Ready biodegradability 18 8.1.2. Bioaccumulation 19 8.2. Ecotoxicological investigations 19 8.2.1. toxicity to fish 19 8.2.2. toxicity to aquatic invertebrates 20 8.2.3. growth inhibition test 20 8.2.4. Inhibition of microbial activity 21 9. RISK ASSESSMENT 21 9.1. Environment 21 9.1.1. Environment exposure assessment 21 – 9.1.2. Environment effects assessment 22 – 9.1.3. Environment risk characterisation 22 – 9.2. Human health 22 9.2.1. Occupational health and safety exposure assessment 22 – 23 Transport, Warehouse and Storage 23 Processing 9.2.2. Public health exposure assessment 24 – 9.2.3. health effects assessment 24 – 9.2.4. Occupational health and safety risk characterisation 25 – 9.2.5. Public health risk characterisation 25 – 10. CONCLUSIONS ASSESSMENT LEVEL OF CONCERN FOR THE ENVIRONMENT AND – HUMANS 26 10.1. Hazard classification 26 10.2. Environmental risk assessment 26 10.3. Human health risk assessment 26 10.3.1. Occupational health and safety 26 10.3.2. Public health 26 11. MATERIAL SAFETY DATA SHEET 26 11.1. Material Safety Data Sheet 26 11.2. Label 26 12. RECOMMENDATIONS 27
TABLE OF CONTENTS FULL PUBLIC REPORT 4 1. APPLICANT AND NOTIFICATION DETAILS 4 2. IDENTITY OF CHEMICAL 4 3. COMPOSITION 5 4. INTRODUCTION AND USE INFORMATION 5 5. PROCESS AND RELEASE INFORMATION 5 5.1. Distribution, transport and storage 5 5.2. Operation description 5 5.3. Occupational exposure 6 Exposure Details 6 5.4. Release 7 5.5. Disposal 7 5.6. Public exposure 7 6. PHYSICAL AND CHEMICAL PROPERTIES 8 7. TOXICOLOGICAL INVESTIGATIONS 10 7.1. Acute toxicity – oral 10 7.2. toxicity – dermal 11 7.3. Acute toxicity – inhalation 11 7.4. Irritation – skin 11 7.5. Irritation – eye 12 7.6. Skin sensitisation 13 7.7. Repeat dose toxicity 14 7.8. Genotoxicity – bacteria 15 7.9. Genotoxicity – in 16 7.10. Genotoxicity – in vivo 17 8. ENVIRONMENT 18 8.1. Environmental fate 18 8.1.1. Ready biodegradability 18 8.1.2. Bioaccumulation 19 8.2. Ecotoxicological investigations 19 8.2.1. toxicity to fish 19 8.2.2. toxicity to aquatic invertebrates 20 8.2.3. growth inhibition test 20 8.2.4. Inhibition of microbial activity 21 9. RISK ASSESSMENT 21 9.1. Environment 21 9.1.1. Environment – exposure assessment 21 9.1.2. Environment – effects assessment 22 9.1.3. Environment – risk characterisation 22 9.2. Human health 22 9.2.1. Occupational health and safety – exposure assessment 22 Transport, Warehouse and Storage 23 Processing 23 9.2.2. Public health – exposure assessment 24 9.2.3. health – effects assessment 24 9.2.4. Occupational health and safety – risk characterisation 25 9.2.5. Public health – risk characterisation 25 10. CONCLUSIONS – ASSESSMENT LEVEL OF CONCERN FOR THE ENVIRONMENT AND HUMANS 26 10.1. Hazard classification 26 10.2. Environmental risk assessment 26 10.3. Human health risk assessment 26 10.3.1. Occupational health and safety 26 10.3.2. Public health 26 11. MATERIAL SAFETY DATA SHEET 26 11.1. Material Safety Data Sheet 26 11.2. Label 26 12. RECOMMENDATIONS 27
STD-1089-FR.docx