Richard 200112 In 2001, Richard and colleagues developed a motor and non-motor states diary. It allowed for hourly, retrospective characterization of the predominant mood, anxiety, and motor states using visual analog scales. The anchors for mood were and “extremely sad” “extremely for anxiety were and and those for happy,” those “extremely calm” “extremely anxious,” motor were and with “extremely immobile (OFF)” “excessively mobile (ON dyskinesia)”. No formal validation testing was conducted. Nyholm 200413 In 2004, Nyholm and colleagues developed a motor and non-motor symptom diary in paper and electronic versions that combined check boxes and visual analog scales response formats. Participants were asked to retrospectively report the average of symptom severity on an hourly basis. No formal validation testing was conducted. Westin 201014,15 Westin and colleagues developed a motor electronic diary (Qtek 2020i Pocket PC, personal digital assistant device) in 2010 that underwent further validation testing in 2012. It allowed participants to characterize 4-times daily their predominant past motor state and symptom severity, and to assess in real time their motor performance with finger tapping and spiral drawing. Validation methods included Cronbach's test-retest reliability 1 week later α=0.85, was 0.73 in non-fluctuators, 0.84 in fluctuators, and 0.88 for both groups combined. Convergent validity was significant for total UPDRS (r = -0.64, p = 0.11) and PDQ-39 (r = -0.72, p=0.02). Known-groups validity between fluctuators and non-fluctuators revealed a median overall score differing by 18% (p=0.001).
Richard 200112 In 2001, Richard and colleagues developed a motor and non-motor states diary. It allowed for hourly, retrospective characterization of the predominant mood, anxiety, and motor states using visual analog scales. The anchors for mood were “extremely sad” and “extremely happy,” those for anxiety were “extremely calm” and “extremely anxious,” and those for motor were “extremely immobile (OFF)” and “excessively mobile (ON with dyskinesia)”. No formal validation testing was conducted. Nyholm 200413 In 2004, Nyholm and colleagues developed a motor and non-motor symptom diary in paper and electronic versions that combined check boxes and visual analog scales response formats. Participants were asked to retrospectively report the average of symptom severity on an hourly basis. No formal validation testing was conducted. Westin 201014,15 Westin and colleagues developed a motor electronic diary (Qtek 2020i Pocket PC, personal digital assistant device) in 2010 that underwent further validation testing in 2012. It allowed participants to characterize 4-times daily their predominant past motor state and symptom severity, and to assess in real time their motor performance with finger tapping and spiral drawing. Validation methods included Cronbach's α=0.85, test-retest reliability 1 week later was 0.73 in non-fluctuators, 0.84 in fluctuators, and 0.88 for both groups combined. Convergent validity was significant for total UPDRS (r = -0.64, p = 0.11) and PDQ-39 (r = -0.72, p=0.02). Known-groups validity between fluctuators and non-fluctuators revealed a median overall score differing by 18% (p=0.001).
SupplementaryMaterial2_092818.docx