TABLE OF CONTENTS FULL PUBLIC REPORT 3 1. APPLICANT AND NOTIFICATION DETAILS 3 2. IDENTITY OF CHEMICAL 3 3. COMPOSITION 4 4. INTRODUCTION AND USE INFORMATION 4 5. PROCESS AND RELEASE INFORMATION 4 5.1. Distribution, transport and storage 4 5.2. Operation description 4 5.3. Occupational exposure 4 5.4. Release 5 5.5. Disposal 5 5.6. Public exposure 5 6. PHYSICAL AND CHEMICAL PROPERTIES 5 7. TOXICOLOGICAL INVESTIGATIONS 8 7.1. Acute toxicity oral 8 – 7.2. Acute toxicity dermal 8 – 7.3. Acute toxicity inhalation 9 – 7.4a. Irritation skin 9 – 7.4b. Irritation skin 10 – 7.5. Irritation eye 11 – 7.6. Skin sensitisation 11 7.7. Repeat dose toxicity - inhalation 12 7.8. Genotoxicity bacteria 14 – 7.9. Genotoxicity in 14 – 8. ENVIRONMENT 15 8.1. Environmental fate 15 8.1.1. Ready biodegradability 15 8.1.2. Bioaccumulation 16 8.2. Ecotoxicological investigations 17 8.2.1. Acute toxicity to fish 17 8.2.2. toxicity to aquatic invertebrates 17 8.2.3. Algal growth inhibition test 18 9. RISK ASSESSMENT 19 9.1. Environment 19 9.1.1. Environment exposure assessment 19 – 9.1.2. Environment effects assessment 19 – 9.1.3. Environment risk characterisation 20 – 9.2. Human health 20 9.2.1. Occupational health and safety exposure assessment 20 – 9.2.2. Public health exposure assessment 20 – 9.2.3. Human health effects assessment 20 – 9.2.4. Occupational health and safety risk characterisation 21 – 9.2.5. Public health risk characterisation 21 – 10. CONCLUSIONS ASSESSMENT LEVEL OF CONCERN FOR THE ENVIRONMENT AND – HUMANS 21 10.1. Hazard classification 21 10.2. Environmental risk assessment 21 10.3. Human health risk assessment 21 10.3.1. Occupational health and safety 21 10.3.2. Public health 21 11. MATERIAL SAFETY DATA 21 11.1. Material Safety Data Sheet 21 11.2. Label 22 12. RECOMMENDATIONS 22 12.1. Secondary notification 22 13. BIBLIOGRAPHY 23
TABLE OF CONTENTS FULL PUBLIC REPORT 3 1. APPLICANT AND NOTIFICATION DETAILS 3 2. IDENTITY OF CHEMICAL 3 3. COMPOSITION 4 4. INTRODUCTION AND USE INFORMATION 4 5. PROCESS AND RELEASE INFORMATION 4 5.1. Distribution, transport and storage 4 5.2. Operation description 4 5.3. Occupational exposure 4 5.4. Release 5 5.5. Disposal 5 5.6. Public exposure 5 6. PHYSICAL AND CHEMICAL PROPERTIES 5 7. TOXICOLOGICAL INVESTIGATIONS 8 7.1. Acute toxicity – oral 8 7.2. Acute toxicity – dermal 8 7.3. Acute toxicity – inhalation 9 7.4a. Irritation – skin 9 7.4b. Irritation – skin 10 7.5. Irritation – eye 11 7.6. Skin sensitisation 11 7.7. Repeat dose toxicity - inhalation 12 7.8. Genotoxicity – bacteria 14 7.9. Genotoxicity – in 14 8. ENVIRONMENT 15 8.1. Environmental fate 15 8.1.1. Ready biodegradability 15 8.1.2. Bioaccumulation 16 8.2. Ecotoxicological investigations 17 8.2.1. Acute toxicity to fish 17 8.2.2. toxicity to aquatic invertebrates 17 8.2.3. Algal growth inhibition test 18 9. RISK ASSESSMENT 19 9.1. Environment 19 9.1.1. Environment – exposure assessment 19 9.1.2. Environment – effects assessment 19 9.1.3. Environment – risk characterisation 20 9.2. Human health 20 9.2.1. Occupational health and safety – exposure assessment 20 9.2.2. Public health – exposure assessment 20 9.2.3. Human health – effects assessment 20 9.2.4. Occupational health and safety – risk characterisation 21 9.2.5. Public health – risk characterisation 21 10. CONCLUSIONS – ASSESSMENT LEVEL OF CONCERN FOR THE ENVIRONMENT AND HUMANS 21 10.1. Hazard classification 21 10.2. Environmental risk assessment 21 10.3. Human health risk assessment 21 10.3.1. Occupational health and safety 21 10.3.2. Public health 21 11. MATERIAL SAFETY DATA 21 11.1. Material Safety Data Sheet 21 11.2. Label 22 12. RECOMMENDATIONS 22 12.1. Secondary notification 22 13. BIBLIOGRAPHY 23
STD1206FR.docx