NN Patient ID Month Loci affected Drug resistance Treatment when profile change outcome VNTR change was registered 1 V014 2 Not Non-MDR MIRU 10: 3→7 → MIRU MDR successful 16: 3→2 MIRU 23: 5→6 MIRU 26: 6→1 MIRU 31: 5→2 MIRU 39: 3→2 ETR-A: 3→4 ETR-C: 4→5 VNTR 424: 4→3 VNTR 1955: 5→3 VNTR 2163b: 5→1 VNTR 3690: 3→5 VNTR 4052: 8→7 2 V016 (new 2 MIRU 16: Non-MDR Successful 1→3 → case) MIRU non-MDR 23: 5→6 MIRU 39: 2→1 MIRU 40: 2→4 ETR-A: 2→3 VNTR 2163b: 2→3 VNTR 3690: 4→3 VNTR 4052: 4→5 3 V025 2 MIRU 10: MDR MDR Not 7→3 → MIRU successful 16: 2→3 MIRU 26: 1→7 MIRU 31: 2→5 MIRU 39: 2→3 ETR-C: 5→4 VNTR 424: 3→4 VNTR 1955: 3→5 VNTR 2163b: 2→6 VNTR 4052: 6→7 4 V026 (new 3 MIRU 2: Non-MDR Not 2→1 → case) MIRU non-MDR successful 10: 3→4 MIRU 16: 1→3 MIRU 27: 4→3 MIRU 31: 3→2 MIRU 40: 4→5 ETR-A: 3→2 ETR-C: 4→2 VNTR 424: 2→3 VNTR 1955: 2→3 VNTR 2163b: 4→2 5 V044 (new 1 MIRU Non-MDR Successful 20: 1→2 → case) MIRU 26: non-MDR 1→7
NN Patient ID Month when VNTR change was registered Loci affected Drug resistance profile change Treatment outcome 1 V014 2 MIRU 10: 3→7 MIRU 16: 3→2 MIRU 23: 5→6 MIRU 26: 6→1 MIRU 31: 5→2 MIRU 39: 3→2 ETR-A: 3→4 ETR-C: 4→5 VNTR 424: 4→3 VNTR 1955: 5→3 VNTR 2163b: 5→1 VNTR 3690: 3→5 VNTR 4052: 8→7 Non-MDR → MDR Not successful 2 V016 (new case) 2 MIRU 16: 1→3 MIRU 23: 5→6 MIRU 39: 2→1 MIRU 40: 2→4 ETR-A: 2→3 VNTR 2163b: 2→3 VNTR 3690: 4→3 VNTR 4052: 4→5 Non-MDR → non-MDR Successful 3 V025 2 MIRU 10: 7→3 MIRU 16: 2→3 MIRU 26: 1→7 MIRU 31: 2→5 MIRU 39: 2→3 ETR-C: 5→4 VNTR 424: 3→4 VNTR 1955: 3→5 VNTR 2163b: 2→6 VNTR 4052: 6→7 MDR → MDR Not successful 4 V026 (new case) 3 MIRU 2: 2→1 MIRU 10: 3→4 MIRU 16: 1→3 MIRU 27: 4→3 MIRU 31: 3→2 MIRU 40: 4→5 ETR-A: 3→2 ETR-C: 4→2 VNTR 424: 2→3 VNTR 1955: 2→3 VNTR 2163b: 4→2 Non-MDR → non-MDR Not successful 5 V044 (new case) 1 MIRU 20: 1→2 MIRU 26: 1→7 Non-MDR → non-MDR Successful
Superinfection_Kontsevaya_et_al_01_12_16.docx