Schrag ADDIN EN.CITE Alzheimer’s disease AD patients vs -0.59 (-1.26, 2013 SUA level ( mg/dl) 10 900 453 Hedge's G Random controls (AD) (discordance in statistical significance) AD patients vs -0.50 (-1.23, Alzheimer’s disease Chen41 2014 SUA level ( mg/dl) 11 2,708 647 SMD Random controls 0.22) (AD) AD patients vs -0.77 (-1.18, Alzheimer’s disease Du42 2016 SUA level (mg/dl) 21 3,617 1,128 MD Random controls (AD) Highest vs lowest SUA Alzheimer’s disease Alzheimer’s patients Du42 2016 3 7,372 NA RR Fixed 0.66 (0.52, 0.85) category (AD) vs controls Bipolar disorder vs Bartoli43 2016 Bipolar disorder SUA level (mg/dl) 9 1,127 619 SMD Random 0.65 (0.33, 0.97) controls Bipolar disorder vs Bartoli43 2016 Bipolar disorder SUA level (mg/dl) 5 735 399 SMD Random 0.46 (0.16, 0.75) major depression Bipolar disorder Depressive vs -0.11 (-0.33, Bartoli43 2016 phase (Depressive vs SUA level (mg/dl) 6 375 NA SMD Random euthymic phase 0.11) euthymic phase) Bipolar disorder Manic/mixed vs Bartoli43 2016 SUA level (mg/dl) 7 472 NA SMD Random 0.34 (0.02, 0.66) phase depressive phase Bipolar disorder Manic/mixed vs 0.19 (-0.10, Bartoli43 2016 SUA level (mg/dl) 6 402 NA SMD Random phase euthymic phase 0.49) Dementia/cognitive Dementia/cognitive -0.33 (-0.48, Khan39 2013 impairment patients SUA level (mg/dl) 31 7,021 2,681 SMD Random impairment vs controls
(discordance in statistical significance) Schrag ADDIN EN.CITE 2013 Alzheimer’s disease (AD) AD patients vs controls SUA level ( mg/dl) 10 900 453 Hedge's G Random -0.59 (-1.26, Chen41 2014 Alzheimer’s disease (AD) AD patients vs controls SUA level ( mg/dl) 11 2,708 647 SMD Random -0.50 (-1.23, 0.22) Du42 2016 Alzheimer’s disease (AD) AD patients vs controls SUA level (mg/dl) 21 3,617 1,128 MD Random -0.77 (-1.18, Du42 2016 Alzheimer’s disease (AD) Alzheimer’s patients vs controls Highest vs lowest SUA category 3 7,372 NA RR Fixed 0.66 (0.52, 0.85) Bartoli43 2016 Bipolar disorder Bipolar disorder vs controls SUA level (mg/dl) 9 1,127 619 SMD Random 0.65 (0.33, 0.97) Bartoli43 2016 Bipolar disorder Bipolar disorder vs major depression SUA level (mg/dl) 5 735 399 SMD Random 0.46 (0.16, 0.75) Bartoli43 2016 Bipolar disorder phase (Depressive vs euthymic phase) Depressive vs euthymic phase SUA level (mg/dl) 6 375 NA SMD Random -0.11 (-0.33, 0.11) Bartoli43 2016 Bipolar disorder phase Manic/mixed vs depressive phase SUA level (mg/dl) 7 472 NA SMD Random 0.34 (0.02, 0.66) Bartoli43 2016 Bipolar disorder phase Manic/mixed vs euthymic phase SUA level (mg/dl) 6 402 NA SMD Random 0.19 (-0.10, 0.49) Khan39 2013 Dementia/cognitive impairment Dementia/cognitive impairment patients vs controls SUA level (mg/dl) 31 7,021 2,681 SMD Random -0.33 (-0.48,
Supplementary%20material_v7%20-%20Final-2.docx