Discussion Risk Patients with Patients Multivariate This comprehensive factors respiratory without analysis report on HAdV complications respiratory pneumonia in n=25 (%) complications n=67 (%) Malaysian children Adjusted P summarises their OR value clinical presentation, (95% identified HAdV types, CI) treatment, risk factors Family 14 (56.0) 11 (16.4) 14.96 0.006 history of asthma for severe disease and both short- and Need for 15(60.0) 2(3.0) 153.77 <0.001 medium-term invasive or respiratory ventilation complications. We Adenovirus 24(96.0) 19(28.0) 9.00 0.024 type 7 found that one in five versus other types children admitted with HAdV pneumonia had severe disease and 22% developed respiratory complications of which PIBO was the commonest problem. Type 7 was the commonest type detected. Family history of asthma, need for ventilation(invasive and non-invasive) and type 7 were independent factors associated with respiratory complications.[15]
Risk factors Patients with respiratory complications n=25 (%) Patients without respiratory complications n=67 (%) Multivariate analysis Adjusted OR (95% CI) P value Family history of asthma 14 (56.0) 11 (16.4) 14.96 0.006 Need for invasive or ventilation 15(60.0) 2(3.0) 153.77 <0.001 Adenovirus type 7 versus other types 24(96.0) 19(28.0) 9.00 0.024 Discussion This comprehensive report on HAdV pneumonia in Malaysian children summarises their clinical presentation, identified HAdV types, treatment, risk factors for severe disease and both short- and medium-term respiratory complications. We found that one in five children admitted with HAdV pneumonia had severe disease and 22% developed respiratory complications of which PIBO was the commonest problem. Type 7 was the commonest type detected. Family history of asthma, need for ventilation(invasive and non-invasive) and type 7 were independent factors associated with respiratory complications.[15]
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