OF CONTENTS FULL PUBLIC REPORT 5 1. APPLICANT AND NOTIFICATION DETAILS 5 2. IDENTITY OF CHEMICAL 5 3. COMPOSITION 5 4. INTRODUCTION AND USE INFORMATION 5 5. PROCESS AND RELEASE INFORMATION 6 5.1. Distribution, Transport and Storage 6 5.2. Operation Description 6 5.3. Occupational exposure 6 5.4. Release 7 5.5. Disposal 7 5.6. Public exposure 7 6. PHYSICAL AND CHEMICAL PROPERTIES 7 7. TOXICOLOGICAL INVESTIGATIONS 9 7.1. toxicity oral 10 – 7.2. Acute toxicity dermal 10 – 7.3. Acute toxicity inhalation 11 – 7.4. Irritation skin 11 – 7.5. Irritation eye 11 – 7.6. Skin sensitisation 12 7.7. Repeat dose toxicity 12 7.8. Genotoxicity bacteria 13 – 7.9. Genotoxicity in vitro 14 – 7.10. Genotoxicity in vivo 15 – 8. ENVIRONMENT 15 8.1. Environmental fate 15 8.1.1. biodegradability 15 8.1.2. Bioaccumulation 15 8.2. Environmental Effects 16 8.2.1. Acute toxicity to fish 16 8.2.2. Acute/chronic toxicity to aquatic invertebrates 16 8.2.3. Algal growth inhibition test 17 8.2.4. Inhibition of microbial activity 17 9. RISK ASSESSMENT 18 9.1. Environment 18 9.1.1. Environment exposure assessment 18 – 9.1.2. Environment effects assessment 18 – 9.1.3. Environment risk characterisation 18 – 9.2. Human health 18 9.2.1. Occupational health and safety exposure assessment 18 – 9.2.2. Public health exposure assessment 18 – 9.2.3. Human health - effects assessment 19 9.2.4. Occupational health and safety risk characterisation 19 – 9.2.5. Public health risk characterisation 19 – 10. CONCLUSIONS ASSESSMENT LEVEL OF CONCERN FOR THE ENVIRONMENT AND – HUMANS 19 10.1. Hazard classification 19 10.2. Environmental risk assessment 19 10.3. Human health risk assessment 20 10.3.1. Occupational health and safety 20 10.3.2. Public health 20 11. MATERIAL SAFETY DATA 20 11.1. Material Safety Data Sheet 20 11.2. Label 20 12. RECOMMENDATIONS 20 12.1. Secondary notification 21 13. BIBLIOGRAPHY 21
OF CONTENTS FULL PUBLIC REPORT 5 1. APPLICANT AND NOTIFICATION DETAILS 5 2. IDENTITY OF CHEMICAL 5 3. COMPOSITION 5 4. INTRODUCTION AND USE INFORMATION 5 5. PROCESS AND RELEASE INFORMATION 6 5.1. Distribution, Transport and Storage 6 5.2. Operation Description 6 5.3. Occupational exposure 6 5.4. Release 7 5.5. Disposal 7 5.6. Public exposure 7 6. PHYSICAL AND CHEMICAL PROPERTIES 7 7. TOXICOLOGICAL INVESTIGATIONS 9 7.1. toxicity – oral 10 7.2. Acute toxicity – dermal 10 7.3. Acute toxicity – inhalation 11 7.4. Irritation – skin 11 7.5. Irritation – eye 11 7.6. Skin sensitisation 12 7.7. Repeat dose toxicity 12 7.8. Genotoxicity – bacteria 13 7.9. Genotoxicity – in vitro 14 7.10. Genotoxicity – in vivo 15 8. ENVIRONMENT 15 8.1. Environmental fate 15 8.1.1. biodegradability 15 8.1.2. Bioaccumulation 15 8.2. Environmental Effects 16 8.2.1. Acute toxicity to fish 16 8.2.2. Acute/chronic toxicity to aquatic invertebrates 16 8.2.3. Algal growth inhibition test 17 8.2.4. Inhibition of microbial activity 17 9. RISK ASSESSMENT 18 9.1. Environment 18 9.1.1. Environment – exposure assessment 18 9.1.2. Environment – effects assessment 18 9.1.3. Environment – risk characterisation 18 9.2. Human health 18 9.2.1. Occupational health and safety – exposure assessment 18 9.2.2. Public health – exposure assessment 18 9.2.3. Human health - effects assessment 19 9.2.4. Occupational health and safety – risk characterisation 19 9.2.5. Public health – risk characterisation 19 10. CONCLUSIONS – ASSESSMENT LEVEL OF CONCERN FOR THE ENVIRONMENT AND HUMANS 19 10.1. Hazard classification 19 10.2. Environmental risk assessment 19 10.3. Human health risk assessment 20 10.3.1. Occupational health and safety 20 10.3.2. Public health 20 11. MATERIAL SAFETY DATA 20 11.1. Material Safety Data Sheet 20 11.2. Label 20 12. RECOMMENDATIONS 20 12.1. Secondary notification 21 13. BIBLIOGRAPHY 21
STD1020FR.docx