To test the long 8 diabetic men Participants Compliance by 3 Minimised by Significant Intervention was Pick 1996 term effects of consumed oat weekly cross-over decreases in total well tolerated. oat bran bran concentrate appointments design. cholesterol and concentrate in and bread including 48hr Difference in LDL-C. No product on products with a recalls. Dietary test products change in HDL-C. diabetes control. mean intake of 9g intake by 4x 48hr bread vs. soluble fibre. recalls in each variety of bread Control products intake period. products) may were white bread. Blood lipids introduce 2x 12wk periods. measured confounding. enzymatically, LDL-C calculated. RMANOVA analysis. To test the effect 64 participants (29% Participants in the Compliance by Dietary fat Significant Amount of Poulter 1994 of cereal male) mean age 56y. oat group returned cereal intake and decrease in soluble fibre on blood Majority of participants consumed a mean and weighing polyunsaturated: cholesterol and consumed by cholesterol in a were recruited from a intake of 56g of of unused cereal. saturated fat LDL-C. No oat group group hypertension clinic and commercially Dietary intake by ratio fluctuated change in HDL-C. unclear representative of not selected on blood available oat 2d food diary at throughout trials (reported as the general lipid status. based cereal per baseline and end 2.24g, but when population. day (2.24g soluble of intervention. calculated from fibre). Blood lipids information in 2x 4wk period. measured paper amount is enzymatically, 3g per day). LDL-C calculated. Statistical analysis by t-test and a method for trials.
Pick 1996 To test the long term effects of oat bran concentrate product on diabetes control. 8 diabetic men Participants consumed oat bran concentrate in and bread products with a mean intake of 9g soluble fibre. Control products were white bread. 2x 12wk periods. Compliance by 3 weekly appointments including 48hr recalls. Dietary intake by 4x 48hr recalls in each intake period. Blood lipids measured enzymatically, LDL-C calculated. RMANOVA analysis. Minimised by cross-over design. Difference in test products bread vs. variety of bread products) may introduce confounding. Significant decreases in total cholesterol and LDL-C. No change in HDL-C. Intervention was well tolerated. Poulter 1994 To test the effect of cereal on blood cholesterol in a group representative of the general population. 64 participants (29% male) mean age 56y. Majority of participants were recruited from a hypertension clinic and not selected on blood lipid status. Participants in the oat group consumed a mean intake of 56g of commercially available oat based cereal per day (2.24g soluble fibre). 2x 4wk period. Compliance by returned cereal and weighing of unused cereal. Dietary intake by 2d food diary at baseline and end of intervention. Blood lipids measured enzymatically, LDL-C calculated. Statistical analysis by t-test and a method for trials. Dietary fat intake and polyunsaturated: saturated fat ratio fluctuated throughout trials Significant decrease in cholesterol and LDL-C. No change in HDL-C. Amount of soluble fibre consumed by oat group unclear (reported as 2.24g, but when calculated from information in paper amount is 3g per day).
SR%20beta-glucan%20cholesterol%20-%20Master%20version.docx