Results for each trial are presented in a format similar to the figure below. Supplementary Appendix B Figure 1. Format for trial level results Outcome Difference Number of Health Economic QALY Economic Total in risk patients service Impact on impact impact on Economic between affected if cost per health service per QALYS Impact control and implemented person costs person treatment at 65% or day Primary Outcome 1 +/-x% A V A * V = C Y A * Y = D C + D Secondary Outcome 2 +/-x% B X B * X = E Z B * Z = F E + F Change in C + D + E + F intervention costs INT C + D E + F +/- INT Total
Results for each trial are presented in a format similar to the figure below. Supplementary Appendix B Figure 1. Format for trial level results Outcome Difference in risk between control and treatment Number of patients affected if implemented at 65% Health service cost per person or day Economic Impact on health service costs QALY impact per person Economic impact on QALYS Total Economic Impact Primary Outcome 1 +/-x% A V A * V = C Y A * Y = D C + D Secondary Outcome 2 +/-x% B X B * X = E Z B * Z = F E + F Change in intervention costs Total INT C + D E + F C + D + E + F +/- INT
Supplementary-Appendix-B-Economic-evaluation-of-investigator-initiated-clinical-trials-conducted-by-networks.docx