2nd line treatment: zanamivir if there is a poor response to oseltamivir or if there is evidence of gastrointestinal dysfunction For further detail see PHE guidelines on use of antiviral agents for the treatment and prophylaxis of seasonal influenza. Oseltamivir for weight and renal dysfunction Weight function Treatment dose Post exposure prophylaxis dose >40 kg Normal 75 mg twice a day 75 mg once a day Cr Cl >60 ml/min for 5 days for 10 days 23-40 kg Normal 60 mg a day 60 mg once a day Cr Cl >60 ml/min for 5 days for 10 days All Moderate impairment 30 mg twice a day 30 mg once a day patients Cr Cl 30-60 ml/min for 5 days for 10 days All Severe impairment 30 mg once a day 30 mg 48 hours patients Cr Cl 10-30 ml/min for 5 days for 10 days All Established renal 30 mg once only 30 mg once, repeated patients impairment after 7 days Cr Cl <10 ml/min Education and Training Program The Health and Social Care Act (Department of Health 2015) stipulates that infection prevention and control training is included for all staff at induction. Hand hygiene training is included in the induction programme. Hand hygiene training is mandatory and is offered to staff annually. Infection prevention and control updates are mandatory and are offered every 2 years. All members of staff have an individual responsibility to ensure that they access mandatory training. and Tell’ machines which are used to demonstrate the effectiveness of hand hygiene ‘Glow techniques are available for loan from the Infection Prevention and Control Team for the use of practices who wish to carry out hand hygiene training in house. The Infection Prevention and Control Team can be contacted on 01623 673081. Review and Revision arrangements This Policy shall be reviewed every 3 years or sooner if the base of evidence indicates an earlier review. References Department of Health (2015) The Health and Social Care Act 2008. London PHE (2016) PHE guidelines on the management of outbreaks of influenza-like illness (ILI) in care homes. Crown Copyright PHE (2017) PHE guidance on use of antiviral agents for the treatment and prophylaxis of seasonal influenza. Copyright
2nd line treatment: zanamivir if there is a poor response to oseltamivir or if there is evidence of gastrointestinal dysfunction For further detail see PHE guidelines on use of antiviral agents for the treatment and prophylaxis of seasonal influenza. Oseltamivir for weight and renal dysfunction Weight function Treatment dose Post exposure prophylaxis dose >40 kg Normal Cr Cl >60 ml/min 75 mg twice a day for 5 days 75 mg once a day for 10 days 23-40 kg Normal Cr Cl >60 ml/min 60 mg a day for 5 days 60 mg once a day for 10 days All patients Moderate impairment Cr Cl 30-60 ml/min 30 mg twice a day for 5 days 30 mg once a day for 10 days All patients Severe impairment Cr Cl 10-30 ml/min 30 mg once a day for 5 days 30 mg 48 hours for 10 days All patients Established renal impairment Cr Cl <10 ml/min 30 mg once only 30 mg once, repeated after 7 days Education and Training Program The Health and Social Care Act (Department of Health 2015) stipulates that infection prevention and control training is included for all staff at induction. Hand hygiene training is included in the induction programme. Hand hygiene training is mandatory and is offered to staff annually. Infection prevention and control updates are mandatory and are offered every 2 years. All members of staff have an individual responsibility to ensure that they access mandatory training. ‘Glow and Tell’ machines which are used to demonstrate the effectiveness of hand hygiene techniques are available for loan from the Infection Prevention and Control Team for the use of practices who wish to carry out hand hygiene training in house. The Infection Prevention and Control Team can be contacted on 01623 673081. Review and Revision arrangements This Policy shall be reviewed every 3 years or sooner if the base of evidence indicates an earlier review. References Department of Health (2015) The Health and Social Care Act 2008. London PHE (2016) PHE guidelines on the management of outbreaks of influenza-like illness (ILI) in care homes. Crown Copyright PHE (2017) PHE guidance on use of antiviral agents for the treatment and prophylaxis of seasonal influenza. Copyright
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