Parallel To compare oat 84 adults aged Oat bran Compliance by On average, the Significant Kashtan 1992 bran effect on 61.3years, 31 men and (88g/day) or comparing 84 participants decrease in total blood lipid in 14 women, with normal wheat bran consumed foods consumed 91% and LDL adults with blood lipid levels supplement composition of dietary cholesterol in oat previous (73g/day), twice according to the calorie. consuming polypectomy per day. Taken subjects’ 43 participants treatment and those with hot or cold records with consumed 90% compared with without such cereal, at both prescribed diets of wheat. No change history breakfast and provided. t-test designated in HDL. dinner. Wheat analysis and supplement and bran diet was ANCOVA diet and results supplemented adjusting baseline include only with cream of values and those. wheat and gender. cheddar cheese, in order to match nutrient profile. Keogh 2003 To test the 18 mildly diet provided Compliance by Minimised by Total cholesterol Data presented effects of a hypercholesterolaemic containing highly urinary nitrogen cross and LDL-C as least square highly -glucan and overweight men enriched b-glucan measures. design and fluctuated means. enriched barley (aged 18-65y). from barley in a Unclear method of provision of total throughout on markers of variety of foods. blood lipid diet. intervention CVD risk. Treatment stratum measurement. period, no consumed ANOVA and t-test significant -glucan/d. analysis. difference Control consumed observed. isoenergetic amount of 6.5-9.2 g glucose/d. 2x 4wk periods, minimum 4wk washout.
Kashtan 1992 Parallel To compare oat bran effect on blood lipid in adults with previous polypectomy and those without such history 84 adults aged 61.3years, 31 men and 14 women, with normal blood lipid levels Oat bran (88g/day) or wheat bran supplement (73g/day), twice per day. Taken with hot or cold cereal, at both breakfast and dinner. Wheat bran diet was supplemented with cream of wheat and cheddar cheese, in order to match nutrient profile. Compliance by comparing consumed foods composition according to the subjects’ records with prescribed diets provided. t-test analysis and ANCOVA adjusting baseline values and gender. On average, the 84 participants consumed 91% of dietary calorie. 43 participants consumed 90% of designated supplement and diet and results include only those. Significant decrease in total and LDL cholesterol in oat consuming treatment compared with wheat. No change in HDL. Keogh 2003 To test the effects of a highly -glucan enriched barley on markers of CVD risk. 18 mildly hypercholesterolaemic and overweight men (aged 18-65y). diet provided containing highly enriched b-glucan from barley in a variety of foods. Treatment stratum consumed -glucan/d. Control consumed isoenergetic amount of 6.5-9.2 g glucose/d. 2x 4wk periods, minimum 4wk washout. Compliance by urinary nitrogen measures. Unclear method of blood lipid measurement. ANOVA and t-test analysis. Minimised by cross design and provision of total diet. Total cholesterol and LDL-C fluctuated throughout intervention period, no significant difference observed. Data presented as least square means.
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