0.69 (NA, NA) <0.001 rs10805346 0.24 (NA, NA) 0.05 rs12498956 7 SNPs in SCL2A9: No overall result 0.53 (NA, NA) 0.001 rs16890979 0.54 (NA, NA) 0.002 rs6832439 Voruganti ADDIN EN.CITE 0.27 (NA, NA) 0.003 rs6449213 NO ADDIN Residual American 2014 3,604 (3)* SCr (mmol/L) 5.3% EN.CITE Indians variance¶ 0.60 (NA, NA) 0.000 rs13131257 0.46 (NA, NA) 0.004 rs737267 0.68 (NA, NA) 0.000 rs10805346 93 (discordance in statistical 0.23 (NA, NA) 0.06 significance) rs12498956 Hughes ADDIN EN.CITE European Genetic risk score of 5 -19.23 (-40.32, 1.86) 0.07 β 2013 7,979 (2)* SCr (mmol/L) 2.3% Caucasian SUA-related SNPs Overall P>0.05 7 SNPs in SCL2A9: Voruganti ADDIN EN.CITE 0.13 (NA, NA) 0.07 rs16890979 Residual American Albumin/creatinine 2014 3,604 (3)* 5.3% Indians ratio variance¶ 0.16 (NA, NA) 0.05 rs6832439 0.01 (NA, NA) 0.64 rs6449213
rs10805346 0.69 (NA, NA) <0.001 rs12498956 0.24 (NA, NA) 0.05 Voruganti ADDIN EN.CITE 2014 American Indians 3,604 (3)* SCr (mmol/L) 7 SNPs in SCL2A9: 5.3% Residual variance¶ No overall result NO ADDIN EN.CITE 93 (discordance in statistical significance) rs16890979 0.53 (NA, NA) 0.001 rs6832439 0.54 (NA, NA) 0.002 rs6449213 0.27 (NA, NA) 0.003 rs13131257 0.60 (NA, NA) 0.000 rs737267 0.46 (NA, NA) 0.004 rs10805346 0.68 (NA, NA) 0.000 rs12498956 0.23 (NA, NA) 0.06 Hughes ADDIN EN.CITE 2013 European Caucasian 7,979 (2)* SCr (mmol/L) Genetic risk score of 5 SUA-related SNPs 2.3% β -19.23 (-40.32, 1.86) 0.07 Voruganti ADDIN EN.CITE 2014 American Indians 3,604 (3)* Albumin/creatinine ratio 7 SNPs in SCL2A9: 5.3% Residual variance¶ Overall P>0.05 rs16890979 0.13 (NA, NA) 0.07 rs6832439 0.16 (NA, NA) 0.05 rs6449213 0.01 (NA, NA) 0.64
Supplementary%20material_v7%20-%20Final-2.docx