research question Van II Middle aged Participants were BP, SBP, 48 4 weeks (4x Mean 24 hour Change in SBP between MAP, adults with randomised to 4 week urinary sodium low sodium & higher cholesterol (2004), cross mild, either: excretion: sodium diets: USA borderline periods) Low sodium Low sodium diet: -16mmHg (SEM: 1.51, study hypertension [] diet: target 95%CI: -18.96-13.04) (not on 24±13mmol/day <40mmol/day medication Change in DBP between High sodium High sodium diet: for duration diets: diet: target 309±88mmol/day of trials) (BP >225mmol/day -8mmHg (SEM: -10.04, 95%CI: -5.96) Participants also Insufficient baseline data maintained to calculate change in –Grade sodium intakes MAP 1– grade 2) of: Change in total cholesterol between low during the first sodium & high sodium and third 4 diets: week periods 3mg/dl(95%CI: -11.82, All sodium 17.82) (from Graudal) targets were achieved through intensive
research question Van (2004), USA [] cross study II Middle aged adults with mild, borderline hypertension (not on medication for duration of trials) (BP –Grade 1– grade 2) Participants were randomised to either: Low sodium diet: target <40mmol/day High sodium diet: target >225mmol/day Participants also maintained sodium intakes of: during the first and third 4 week periods All sodium targets were achieved through intensive BP, SBP, MAP, cholesterol 48 4 weeks (4x 4 week periods) Mean 24 hour urinary sodium excretion: Low sodium diet: 24±13mmol/day High sodium diet: 309±88mmol/day Change in SBP between low sodium & higher sodium diets: -16mmHg (SEM: 1.51, 95%CI: -18.96-13.04) Change in DBP between diets: -8mmHg (SEM: -10.04, 95%CI: -5.96) Insufficient baseline data to calculate change in MAP Change in total cholesterol between low sodium & high sodium diets: 3mg/dl(95%CI: -11.82, 17.82) (from Graudal)
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx