Key features for bias assessment of randomised trials Citation Method of Allocation Blinding Loss to Use of Ceasing study early Reporting all Funding randomisation concealment follow-up for benefit outcome source where results required Swift et al Unclear (method of Low risk Participants: 7 lost (1 Only reported No (Low risk) unclear, Placebo & (2005) randomisation not (pharmacy blinded, Low during data from reported slow described) conducted) risk phase, 6 participants baseline total sodium following that cholesterol, tablets Providers: completed the triglycerides provided blinded to 14% study, but but no data by CIBA, allocation, (low risk) unlikely to post unlikely Low risk affect results, intervention, conflict, Low risk also 24hr ABP Low Outcome baseline data risk(low assessors: not provided risk) unclear Summary table Citation Study Population Intervention Outcomes Sample Compliance to Results & design level measured size duration sodium target location of relevant to (urinary data)
Key features for bias assessment of randomised trials Citation Method of randomisation Allocation concealment Blinding Loss to follow-up Use of where required Ceasing study early for benefit Reporting all outcome results Funding source Swift et al (2005) Unclear (method of randomisation not described) Low risk (pharmacy conducted) Participants: blinded, Low risk Providers: blinded to allocation, Low risk Outcome assessors: unclear 7 lost (1 during phase, 6 following 14% (low risk) Only reported data from participants that completed the study, but unlikely to affect results, Low risk No (Low risk) unclear, reported baseline total cholesterol, triglycerides but no data post intervention, also 24hr ABP baseline data not provided Placebo & slow sodium tablets provided by CIBA, unlikely conflict, Low risk(low risk) Summary table Citation & location Study design level of Population Intervention Outcomes measured relevant to Sample size duration Compliance to sodium target (urinary data) Results
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