Citation Study Population Intervention Outcomes Sample Compliance to Results & design level measured size duration sodium target location of relevant to (urinary data) research question II Adults (aged 25 Participants randomly 351 (in 3 years Difference in Mean difference pressure 49 years) with assigned to one of five groups 1 change in between reduced – (sitting parallel diastolic blood groups: and 3, urinary sodium sodium and after 5 min design pressure of 76 n= 841 between control groups: – rest), 1. control (no dietary Research study 90mmHg in whole reduced sodium mortality counselling) - SBP: (SEM: Group study) and control also noted. 0.99, CI: -1.84, (1990), groups (sodium 2. reduced calories 2.04) USA control): – (participants with high BMI only) DBP: 0.2mmHg [] -4.2 (SEM: 2.1) (SEM: 0.71, CI: mmol/8 hr 3. reduced sodium (goal of 1.59) urinary sodium excretion < 70mmol/day) Mortality reported as one 4. reduced sodium and death each in calories (participants with high control and BMI only) (goal of urinary reduced sodium sodium excretion < groups (no 70mmol/day) statistical analysis reported) 5. reduced sodium and increased potassium (goal of urinary sodium excretion < 70mmol/day, urinary
Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size duration Compliance to sodium target (urinary data) Results Research Group (1990), USA [] parallel design study II Adults (aged 25 – 49 years) with diastolic blood pressure of 76 – 90mmHg Participants randomly assigned to one of five groups: 1. control (no dietary counselling) - 2. reduced calories (participants with high BMI only) 3. reduced sodium (goal of urinary sodium excretion < 70mmol/day) 4. reduced sodium and calories (participants with high BMI only) (goal of urinary sodium excretion < 70mmol/day) 5. reduced sodium and increased potassium (goal of urinary sodium excretion < 70mmol/day, urinary pressure (sitting after 5 min rest), mortality also noted. 351 (in groups 1 and 3, n= 841 in whole study) 3 years Difference in change in urinary sodium between reduced sodium and control groups (sodium – control): -4.2 (SEM: 2.1) mmol/8 hr Mean difference between reduced sodium and control groups: SBP: (SEM: 0.99, CI: -1.84, 2.04) DBP: 0.2mmHg (SEM: 0.71, CI: 1.59) Mortality reported as one death each in control and reduced sodium groups (no statistical analysis reported)
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx