Fagerberg Unclear risk (no Unclear risk (not Participants: 12% (however No (high risk) No (low Yes (low risk) Swedish National et al. description of described) high risk unclear from risk) Association Against (1984) method of which study Heart and Chest Providers: high sequence group) Diseases, Swedish – risk generation) unclear risk Medical Research Council, Goteborg Outcome Medical Society (low assessors: risk) unclear risk Summary Citation Study Population Intervention Outcomes Sample size Intervention Compliance to Results & design level measured duration sodium target location of relevant to (urinary data) research question Fotherby II Older adults All participants Blood pressure 17 5 Normal sodium Mean difference (supine after 5 et al. (aged 66 79 were prescribed a period: 174 + 40 between low – min rest and (1993) years) with reduced sodium mmol/24hr sodium diet to after 1 min and over essential diet normal sodium standing) Low sodium Fotherby study hypertension for diet: (reported in period: 95 + 36 et al. (SBP: > 4 trial. Following Fotherby et mmol/24hr Supine: (1997), 160mmHg, this period, they al., 1993). Total UK DBP: > 95 were then (p<0.01) SBP: -8mmHg cholesterol, mmHg) randomly allocated (SEM: 3.5, CI: [, ] HDL and LDL to a cross-over -1.14) (reported in arm: Fotherby et al., 1997)
Fagerberg et al. (1984) Unclear risk (no description of method of sequence generation) Unclear risk (not described) Participants: high risk Providers: high risk Outcome assessors: unclear risk 12% (however unclear from which study group) – unclear risk No (high risk) No (low risk) Yes (low risk) Swedish National Association Against Heart and Chest Diseases, Swedish Medical Research Council, Goteborg Medical Society (low risk) Summary Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size Intervention duration Compliance to sodium target (urinary data) Results Fotherby et al. (1993) and Fotherby et al. (1997), UK [, ] study II Older adults (aged 66 – 79 years) with essential hypertension (SBP: > 160mmHg, DBP: > 95 mmHg) All participants were prescribed a reduced sodium diet for 4 Following this period, they were then randomly allocated to a cross-over arm: Blood pressure (supine after 5 min rest and after 1 min standing) (reported in Fotherby et al., 1993). Total cholesterol, HDL and LDL (reported in Fotherby et al., 1997) 17 5 Normal sodium period: 174 + 40 mmol/24hr Low sodium period: 95 + 36 mmol/24hr (p<0.01) Mean difference between low sodium diet to normal sodium diet: Supine: SBP: -8mmHg (SEM: 3.5, CI: -1.14) over trial.
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