Citation Method of Allocation Blinding Loss to Use of Ceasing study Reporting Funding source randomisation concealment follow-up early for all where benefit outcome required results Andersson Unclear risk (no Unclear risk (no Participants: 0% (low Not required No (low risk) Yes (low Swedish National et al. description of description of unclear risk risk) (low risk) risk) Association Against (1984) method of method of Heart and Chest Providers: sequence concealment of Diseases, Goteborg high risk generation) allocation) Medical Society (low risk). Outcome assessors: unclear risk Summary table Citation Study Population Intervention Outcomes Sample Intervention Compliance to Results & design level measured size duration sodium target location of relevant to (urinary data) research question II Adults, mild Participants were then Blood 200 12 weeks Low sodium trial: Mean changes pressure hypertensive randomised to one of four (n=100 in 85.8 + 7.1 between low (seated), (1986), parallel (DBP: 90 groups: sodium mmol/24hr sodium diet to – cholesterol Australia design 100mmHg) and normal sodium (did not 1. Normal diet group Normal sodium control diet (from report [] 155.6 + groups) Graudal): values for 8.4mmol/24hr calculating change)
Citation Method of randomisation Allocation concealment Blinding Loss to follow-up Use of where required Ceasing study early for benefit Reporting all outcome results Funding source Andersson et al. (1984) Unclear risk (no description of method of sequence generation) Unclear risk (no description of method of concealment of allocation) Participants: unclear risk Providers: high risk Outcome assessors: unclear risk 0% (low risk) Not required (low risk) No (low risk) Yes (low risk) Swedish National Association Against Heart and Chest Diseases, Goteborg Medical Society (low risk). Summary table Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size Intervention duration Compliance to sodium target (urinary data) Results (1986), Australia [] parallel design II Adults, mild hypertensive (DBP: 90 – 100mmHg) Participants were then randomised to one of four groups: 1. Normal diet group Blood pressure (seated), cholesterol (did not report values for calculating change) 200 (n=100 in sodium and control groups) 12 weeks Low sodium 85.8 + 7.1 mmol/24hr Normal sodium 155.6 + 8.4mmol/24hr Mean changes between low sodium diet to normal sodium diet (from Graudal): trial:
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx