Citation Method of Allocation Blinding Loss to Use of Ceasing Reporting all Funding source randomisation concealment study early outcome results where for benefit required Morgan et Unclear risk Unclear risk Participants: None reported Not required No (low risk) Unclear risk (Did Department of al. (1981) (method of (method of unclear risk (low risk) (low risk) not report Veterans Affairs randomisation not allocation changes in SBP and National Providers: stated) concealment not in sufficient Health and high risk stated) detail to be able Medical to calculate for Research Outcome each (same Council (low assessors: low for standing SBP risk) risk and DBP)) Summary table Citation Study Population Intervention Outcomes Sample Compliance to Results & design level measured size sodium target location of relevant to duration (urinary data) research question Morgan II Trial males Participants pressure 20 6 months Restricted SBP: (supine, et al. (aged 50 65 randomly divided sodium group: – Control initial (prior to standing) (1987), parallel years), with into two groups: 75 + 7 medication cessation: 143 + Australia design hypertension mmol/24hr Note: results 1. normal diet 5mmHg study treated with not provided []
Citation Method of randomisation Allocation concealment Blinding Loss to Use of where required Ceasing study early for benefit Reporting all outcome results Funding source Morgan et al. (1981) Unclear risk (method of randomisation not stated) Unclear risk (method of allocation concealment not stated) Participants: unclear risk Providers: high risk Outcome assessors: low risk None reported (low risk) Not required (low risk) No (low risk) Unclear risk (Did not report changes in SBP in sufficient detail to be able to calculate for each (same for standing SBP and DBP)) Department of Veterans Affairs and National Health and Medical Research Council (low risk) Summary table Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size duration Compliance to sodium target (urinary data) Results Morgan et al. (1987), Australia [] parallel design study II males (aged 50 – 65 years), with hypertension treated with Participants randomly divided into two groups: 1. normal diet pressure (supine, standing) Note: results not provided 20 6 months Restricted sodium group: 75 + 7 mmol/24hr SBP: Control initial (prior to medication cessation: 143 + 5mmHg Trial
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx