PART 9: METABOLISM OF NONNUTRITIVE SUBSTANCES [Objectives] Master botransformation of substances by conjugation reactions, heme is synthesized from succinyl-CoA and glycine, bile acids are formed from cholesterol, entertohepatic circulation Understand various factors affects the activities of the enzymes metabolizing xenobiotics , structure of porphyrins , and metabolism of bilirubin. [Contents] Biotransformation of Nonnutritive Substance Biotransformation Biotransformation of substances by oxidation Biotransformation of substances by reduction Biotransformation of substances by hydrolysis Conjugation reactions prepare the substances for excretion in phase two of their metabolism Various factors affects the activities of the enzymes metabolizing xenobiotics Metabolism of Porphyrins and Bile Pigments Porphyrins and bile pigments Structure of porphyrins Heme is synthesized from succinyl-CoA and glycine Formation and transportation of bilirubin Metabolism of bilirubin Hyperbilirubinemia causes jaundice
PART 9: METABOLISM OF NONNUTRITIVE SUBSTANCES [Objectives] Master botransformation of substances by reactions, heme is synthesized from succinyl-CoA and glycine, bile acids are formed from cholesterol, entertohepatic circulation Understand various factors affects the activities of the enzymes metabolizing xenobiotics , structure of porphyrins , and metabolism of bilirubin. [Contents] Biotransformation of Nonnutritive Substance Biotransformation Biotransformation of substances by oxidation Biotransformation of substances by reduction Biotransformation of substances by hydrolysis Conjugation reactions prepare the substances for excretion in phase two of their metabolism Various factors affects the activities of the enzymes metabolizing xenobiotics Metabolism of Porphyrins and Bile Pigments Porphyrins and bile pigments Structure of porphyrins Heme is synthesized from succinyl-CoA and glycine Formation and transportation of bilirubin Metabolism of bilirubin Hyperbilirubinemia causes jaundice conjugation
2.Basic-medical-sciences-syllabus-for-international-students-1.docx