3. High sodium Cholesterol: 0.04mmol/L (CI: (150mmol/day) -0.04, 0.13) plus DASH or HDL: 0.01mmol/L (CI: -0.02, control diet 0.03) LDL: 0.01mmol/L (CI: -0.06, 0.09) Key features for bias assessment of randomised trials Citation Method of Allocation Blinding Loss to Use of Ceasing Reporting all Funding source randomisation concealment early outcome where for benefit results required DASH 2001 Low risk Low risk Participants: 5.4% loss to Yes (low risk) No (low Yes (low risk) National Heart, Lung (computer (Allocation High risk follow-up (low risk) and Blood Institute, - Sacks et generated occurred at risk) General Clinical al. (2001) Providers: sequence used) central location) Research Center high risk Program of the National - Vollmer Center for Research et al. Outcome Resources (low risk) (2001) assessors: low risk - Harsha et al. (2004)
3. High sodium (150mmol/day) plus DASH or control diet Cholesterol: 0.04mmol/L (CI: -0.04, 0.13) HDL: 0.01mmol/L (CI: -0.02, 0.03) LDL: 0.01mmol/L (CI: -0.06, 0.09) Key features for bias assessment of randomised trials Citation Method of randomisation Allocation concealment Blinding Loss to Use of where required Ceasing early for benefit Reporting all outcome results Funding source DASH 2001 - Sacks et al. (2001) - Vollmer et al. (2001) - Harsha et al. (2004) Low risk (computer generated sequence used) Low risk (Allocation occurred at central location) Participants: High risk Providers: high risk Outcome assessors: low risk 5.4% loss to follow-up (low risk) Yes (low risk) No (low risk) Yes (low risk) National Heart, Lung and Blood Institute, General Clinical Research Center Program of the National Center for Research Resources (low risk)
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx