Note study also divided by Control group: Sodium restriction included a group gender 170 + 15 pre-diet: 97mmHg of pts. with DBP mmol/24hr Sodium restriction >105mmHg, Females post-diet: 87mmHg control group was (p<0.01 compared to treated with Restricted sodium start value, p<0.05 chlorothiazide. As group: 58 + 7 compared to control) it is not possible to mmol/24hr isolate the effect Females (p<0.001 of sodium in these compared to DBP: participants, they start) were not included Control pre-diet: in this analysis Control 125 94mmHg (SD not (results given + 10 mmol/24hr given, all SD’s stated separately in the to be than + 7’) ‘less paper). Control post-diet: 92mmHg Sodium restriction pre-diet: 95mmHg Sodium restriction post-diet: 89mmHg (p<0.01 compared to start value) Key features for bias assessment of randomised trials
Note study also included a group of pts. with DBP >105mmHg, control group was treated with chlorothiazide. As it is not possible to isolate the effect of sodium in these participants, they were not included in this analysis (results given separately in the paper). divided by gender Control group: 170 + 15 mmol/24hr Females Restricted sodium group: 58 + 7 mmol/24hr (p<0.001 compared to start) Control 125 + 10 mmol/24hr Sodium restriction pre-diet: 97mmHg Sodium restriction post-diet: 87mmHg (p<0.01 compared to start value, p<0.05 compared to control) Females DBP: Control pre-diet: 94mmHg (SD not given, all SD’s stated to be ‘less than + 7’) Control post-diet: 92mmHg Sodium restriction pre-diet: 95mmHg Sodium restriction post-diet: 89mmHg (p<0.01 compared to start value) Key features for bias assessment of randomised trials
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx