1. low sodium diet Low sodium diet: SBP: -0.1mmHg plus 100mmol 70 mmol/24hr (SEM: 2.72, CI: NaCl tablets/day 5.23) Normal sodium and alcohol diet: 130 DBP: 0.8mmHg intake mmol/24hr (SEM: 1.57, CI: 2. low sodium diet (estimated from 3.88) plus placebo and figure) Low alcohol usual alcohol Low alcohol participants: intake participants: SBP: (SEM: 3. low sodium diet Low sodium diet: 2.15, CI: -2.01, 6.41) plus 100mmol 60 mmol/24hr NaCl tablets/day DBP: 0.5mmHg and low alcohol Normal sodium (SEM: CI: beer diet: 140 2.79) mmol/24hr 4. low sodium diet (estimated from plus placebo and figure) low alcohol beer Key features for bias assessment of randomised trials Citation Method of Allocation Blinding Loss to Use of Ceasing Reporting all outcome Funding source randomisation concealment study results where early for required benefit
1. low sodium diet plus 100mmol NaCl tablets/day and alcohol intake 2. low sodium diet plus placebo and usual alcohol intake 3. low sodium diet plus 100mmol NaCl tablets/day and low alcohol beer 4. low sodium diet plus placebo and low alcohol beer Low sodium diet: 70 mmol/24hr Normal sodium diet: 130 mmol/24hr (estimated from figure) Low alcohol participants: Low sodium diet: 60 mmol/24hr Normal sodium diet: 140 mmol/24hr (estimated from figure) SBP: -0.1mmHg (SEM: 2.72, CI: 5.23) DBP: 0.8mmHg (SEM: 1.57, CI: 3.88) Low alcohol participants: SBP: (SEM: 2.15, CI: -2.01, 6.41) DBP: 0.5mmHg (SEM: CI: 2.79) Key features for bias assessment of randomised trials Citation Method of randomisation Allocation concealment Blinding Loss to Use of where required Ceasing study early for benefit Reporting all outcome results Funding source
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx