Citation Method of Allocation Blinding Loss to Use of Ceasing study Reporting all Funding randomisation concealment early for benefit outcome source where results required Dubbert Low risk (random Unclear risk Participants: >20% (high No (high risk) No (low risk) Unclear risk Department et al. number table) (randomisation unclear risk risk) (Limited detail of Veteran’s (1995) procedure available on Affairs (low Providers: high stratified by race) significance risk) risk level of changes in Outcome urinary assessors: sodium levels) unclear risk Summary table Citation Study Population Intervention Outcomes Sample Intervention Compliance Results & design level measured size duration to sodium location of relevant to target research (urinary question data) II Adults with Participants Blood pressure 94 24 weeks During Mean difference between (after 10 mins et al. mild allocated to either: (placebo placebo low sodium diet to normal supine rest (1984), parallel hypertension duration 12 period: sodium diet (from Graudal, and after 2 1. Normal diet design (DBP: 95 weeks) not clear if this is placebo – mins Normal study 110mmHg) period only): 2. Sodium standing), sodium cholesterol restricted diet – [] period: 130 + and HDL
Citation Method of randomisation Allocation concealment Blinding Loss to Use of where required Ceasing study early for benefit Reporting all outcome results Funding source Dubbert et al. (1995) Low risk (random number table) Unclear risk (randomisation procedure stratified by race) Participants: unclear risk Providers: high risk Outcome assessors: unclear risk >20% (high risk) No (high risk) No (low risk) Unclear risk (Limited detail available on significance level of changes in urinary sodium levels) Department of Veteran’s Affairs (low risk) Summary table Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size Intervention duration Compliance to sodium target (urinary data) Results et al. (1984), [] parallel design study II Adults with mild hypertension (DBP: 95 – 110mmHg) Participants allocated to either: 1. Normal diet 2. Sodium restricted diet – Blood pressure (after 10 mins supine rest and after 2 mins standing), cholesterol and HDL 94 24 weeks (placebo duration 12 weeks) During placebo period: Normal sodium period: 130 + Mean difference between low sodium diet to normal sodium diet (from Graudal, not clear if this is placebo period only):
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