Summary table Citation Study Population Intervention Outcomes Sample Compliance to Results & design level measured size sodium target location of relevant to duration (urinary data) research question Cobiac et II Older adults During the 2 week run-in Blood pressure 106 (54 in 4 weeks Sunflower oil Mean changes (seated after al. aged 60 80 phase, all participants were sunflower groups: between low – at least 5 min (1992), parallel years, encouraged to reduce oil sodium diet to rest) Normal sodium Australia design sodium intake to less than groups, normal sodium period: 152 + 10 study and mildly 70mmol/day. Participants 52 in fish diet: [] mmol/24hr hypertensive were also provided with oil Sunflower oil (DBP: < NaCl tablets providing groups) Low sodium period: groups: 105mmHg) 80mmol sodium/day and 79 + 7 mmol/24hr (mean 8g sunflower oil capsules (p<0.001 compared SBP: -2.7mmHg during this time. to run-in phase) (SEM: 4.99, CI: Participants were then 7.08) Fish oil groups: randomised to one of four DBP: 0.6mmHg groups: Normal sodium (SEM: 3.92, CI: period: 145 + 8 1. sunflower oil (5g) with 8.28) mmol/24hr normal sodium (with Fish oil groups: tablets providing 80mmol Low sodium period: sodium/day) 70 + SBP: -3.1mmHg (SEM: 5.86, CI: 8.39)
Summary table Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size duration Compliance to sodium target (urinary data) Results Cobiac et al. (1992), Australia [] parallel design study II Older adults aged 60 – 80 years, and mildly hypertensive (DBP: < 105mmHg) (mean During the 2 week run-in phase, all participants were encouraged to reduce sodium intake to less than 70mmol/day. Participants were also provided with NaCl tablets providing 80mmol sodium/day and 8g sunflower oil capsules during this time. Participants were then randomised to one of four groups: 1. sunflower oil (5g) with normal sodium (with tablets providing 80mmol sodium/day) Blood pressure (seated after at least 5 min rest) 106 (54 in sunflower oil groups, 52 in fish oil groups) 4 weeks Sunflower oil groups: Normal sodium period: 152 + 10 mmol/24hr Low sodium period: 79 + 7 mmol/24hr (p<0.001 compared to run-in phase) Fish oil groups: Normal sodium period: 145 + 8 mmol/24hr Low sodium period: 70 + Mean changes between low sodium diet to normal sodium diet: Sunflower oil groups: SBP: -2.7mmHg (SEM: 4.99, CI: 7.08) DBP: 0.6mmHg (SEM: 3.92, CI: 8.28) Fish oil groups: SBP: -3.1mmHg (SEM: 5.86, CI: 8.39)
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