Citation Study Population Intervention Outcomes Sample Compliance to Results & design level measured size duration sodium target location of relevant to (urinary data) research question Jablonski II Adults (50 79 All participants Blood pressure 17 5 Normal sodium SBP: – (supine), total et al. years), with were instructed to diet: 153 + 27 Baseline: 138 + 7 mmHg cholesterol, (2013), high-normal or reduce dietary mmol/day LDL, HDL. UK Stage 1 systolic sodium intake to Low sodium: 128 + Note: vascular Low sodium study hypertension ~50mmol/day. 10mmHg (p<0.01) endothelial [] diet: 70 + 30 (SBP: 130 Participants were function – mmHg Normal sodium: 140 + 159mmHg, DBP: randomised to appears to be the primary 15mmHg <99mmHg) start one of two (p<0.001) outcome study arms: DBP: 1. Reduced salt Baseline: 83 + 7 mmHg diet with 100mmol sodium/day from Low sodium: 79 + 6mmHg NaCl tablets Normal sodium: 82 + 2. Reduced salt 6mmHg diet with placebo Total cholesterol: Baseline: 196 + 27 mg/dL Low sodium: 187 + 27mg/dL Normal sodium: 194 + 22 mg/dL
Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size duration Compliance to sodium target (urinary data) Results Jablonski et al. (2013), UK [] study II Adults (50 – 79 years), with high-normal or Stage 1 systolic hypertension (SBP: 130 – 159mmHg, DBP: <99mmHg) All participants were instructed to reduce dietary sodium intake to ~50mmol/day. Participants were randomised to start one of two study arms: 1. Reduced salt diet with 100mmol sodium/day from NaCl tablets 2. Reduced salt diet with placebo Blood pressure (supine), total cholesterol, LDL, HDL. Note: vascular endothelial function appears to be the primary outcome 17 5 Normal sodium diet: 153 + 27 mmol/day Low sodium diet: 70 + 30 mmHg (p<0.001) SBP: Baseline: 138 + 7 mmHg Low sodium: 128 + 10mmHg (p<0.01) Normal sodium: 140 + 15mmHg DBP: Baseline: 83 + 7 mmHg Low sodium: 79 + 6mmHg Normal sodium: 82 + 6mmHg Total cholesterol: Baseline: 196 + 27 mg/dL Low sodium: 187 + 27mg/dL Normal sodium: 194 + 22 mg/dL
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