(participants instructed to information on (note data is for SBP: -6.7mmHg avoid all foods with baseline data placebo periods (SEM: 9.75, CI: added sodium and select in paper only) -25.81, 12.41) low sodium bread) DBP: 3.2mmHg (only groups 1 and 2 used (SEM: 5.91, CI: by Graudal in analysis) -8.38, 14.78) 3. regular diet + diuretics (100mg spironolactone + 100mg hydrochlorothiazide) 4. moderate sodium restriction + diuretics Key features for bias assessment of randomised trials Citation Method of Allocation Blinding Loss to Use of Ceasing Reporting all Funding source randomisation concealment study outcome results where early for required benefit
(participants instructed to avoid all foods with added sodium and select low sodium bread) (only groups 1 and 2 used by Graudal in analysis) 3. regular diet + diuretics (100mg spironolactone + 100mg hydrochlorothiazide) 4. moderate sodium restriction + diuretics information on baseline data in paper (note data is for placebo periods only) SBP: -6.7mmHg (SEM: 9.75, CI: -25.81, 12.41) DBP: 3.2mmHg (SEM: 5.91, CI: -8.38, 14.78) Key features for bias assessment of randomised trials Citation Method of randomisation Allocation concealment Blinding Loss to Use of where required Ceasing study early for benefit Reporting all outcome results Funding source
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx