TOHP, Unclear risk Low risk Participants: <5% loss to Yes (low risk) No (low risk) Yes (low National II (method of (Concealment of unclear risk follow-up (low risk) Lung, and Blood randomisation not allocation at a risk) Institute, Providers: described) central location) National high risk Institutes of Health (low risk) Outcome assessors: low risk Summary table Citation Study Population Intervention Sample Compliance to Results & design level size sodium target location of measured (urinary data) relevant to research question Schorr et II Normotensive Participants were all Resting 16 4 weeks 24 hour Comparison between high sodium BP, lipids, al. adults (aged counselled to reduce per urinary chloride and placebo treatment 24 hour placebo dietary salt intake to (from Graudal which compared <100mmol/day prior
TOHP, II Unclear risk (method of randomisation not described) Low risk (Concealment of allocation at a central location) Participants: unclear risk Providers: high risk Outcome assessors: low risk <5% loss to follow-up (low risk) Yes (low risk) No (low risk) Yes (low risk) National Lung, and Blood Institute, National Institutes of Health (low risk) Summary table Citation & location Study design level of Population Intervention measured relevant to research question Sample size Compliance to sodium target (urinary data) Results Schorr et al. placebo II Normotensive adults (aged Participants were all counselled to reduce dietary salt intake to <100mmol/day prior Resting BP, lipids, 24 hour 16 4 weeks per 24 hour urinary Comparison between high sodium chloride and placebo treatment (from Graudal which compared
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