2. Liquid dietary pressure) Low sodium Low sodium: 200 + 26 supplement reported diet: 10 + 10 mg%/100mL containing mmHg Intermediate sodium: 200 + 210mEq (p<0.05) 25 mg%/100mL sodium/day High sodium: 211 + 29 3. Liquid dietary mg%/100mL supplement containing 410mEq sodium/day Key features for bias assessment of randomised trials Citation Method of Allocation Blinding Loss to Use of Ceasing early Reporting Funding source randomisation concealment for benefit all where outcome required results Kirkendall Low risk (modified Unclear risk Participants: No loss to Not required No (low risk) Reported National et al. square (method of low risk follow up (low (low risk) no Institutes of (1975) design) allocation risk) significant Health (low risk) Providers: concealment not change in unclear risk described) BP, but only Outcome reported assessors: low mean BP risk values
2. Liquid dietary supplement containing 210mEq sodium/day 3. Liquid dietary supplement containing 410mEq sodium/day pressure) reported Low sodium diet: 10 + 10 mmHg (p<0.05) Low sodium: 200 + 26 mg%/100mL Intermediate sodium: 200 + 25 mg%/100mL High sodium: 211 + 29 mg%/100mL Key features for bias assessment of randomised trials Citation Method of randomisation Allocation concealment Blinding Loss to Use of where required Ceasing early for benefit Reporting all outcome results Funding source Kirkendall et al. (1975) Low risk (modified square design) Unclear risk (method of allocation concealment not described) Participants: low risk Providers: unclear risk Outcome assessors: low risk No loss to follow up (low risk) Not required (low risk) No (low risk) Reported no significant change in BP, but only reported mean BP values National Institutes of Health (low risk)
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx