Summary table Citation Study Population Intervention Outcomes Sample Intervention Compliance to Results & design level measured size duration sodium target location of relevant to (urinary data) research question Maxwell II Participants were Blood pressure 30 12 weeks Low sodium Mean Obese adults, (seated) et al. randomised to supplement: 39 + difference with (1984), parallel consume one of two 4mEq/24hr between low hypertension USA design dietary supplements sodium Normal sodium (DBP: > study as meal replacements: supplement [] supplement: 200 + 90mmHg) and normal 1.320 calories/day as 30mEq/24hr sodium 30g of CHO and 45g of supplement: Note results are protein, plus 600mg from week 8 of 12 calcium, 350mg SBP: week study, results phosphorus, 150mg (SEM: 6.72, CI: from week 12 not magnesium, 100% -15.17, 11.17) given daily allowance of DBP: 2mmHg iron, copper, zinc, and (SEM: 3.84, CI: all vitamins. Total -5.53, 9.53) potassium intake was 60mEq/day, sodium was 40mEq/day 2. Same dietary supplement with same potassium intake, however sodium was
Summary table Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size Intervention duration Compliance to sodium target (urinary data) Results Maxwell et al. (1984), USA [] parallel design study II Obese adults, with hypertension (DBP: > 90mmHg) Participants were randomised to consume one of two dietary supplements as meal replacements: 1.320 calories/day as 30g of CHO and 45g of protein, plus 600mg calcium, 350mg phosphorus, 150mg magnesium, 100% daily allowance of iron, copper, zinc, and all vitamins. Total potassium intake was 60mEq/day, sodium was 40mEq/day 2. Same dietary supplement with same potassium intake, however sodium was Blood pressure (seated) 30 12 weeks Low sodium supplement: 39 + 4mEq/24hr Normal sodium supplement: 200 + 30mEq/24hr Note results are from week 8 of 12 week study, results from week 12 not given Mean difference between low sodium supplement and normal sodium supplement: SBP: (SEM: 6.72, CI: -15.17, 11.17) DBP: 2mmHg (SEM: 3.84, CI: -5.53, 9.53)
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