Gates et Unclear risk (no Unclear risk (not Participants: No loss to Not required No (low risk) Yes (low National Institute al. (2004) description of described) low risk follow up (low (low risk) risk) of NCRR method of risk) General Clinical Providers: low sequence Research Centre, risk generation) American Heart Association (low Outcome risk) assessors: unclear risk Summary table Citation Study Population Intervention Outcomes Sample Intervention Compliance to Results & design level measured size duration sodium target location of relevant to (urinary data) research question Gillies et II Adults with Participants Blood pressure 24 6 Salt restriction Mean difference (supine and al. moderate randomly allocated resulted in between low sodium standing), (1984), hypertension, to on one of decrease from diet to normal sodium MAP Australia over some receiving two cross-over 169mmol/24hr diet: study arms: (SEM: 13) to Note: specific [] Supine: 92mmol/24hr values for 1. Dietary advice medication (SEM: 7) unclear MAP not given – SBP: -2.4mmHg (SEM: for moderate in study, (information on if this change was 2.51, CI: -7.32, 2.52) dietary salt stated as number of from baseline or restriction having no participants on
Gates et al. (2004) Unclear risk (no description of method of sequence generation) Unclear risk (not described) Participants: low risk Providers: low risk Outcome assessors: unclear risk No loss to follow up (low risk) Not required (low risk) No (low risk) Yes (low risk) National Institute of NCRR General Clinical Research Centre, American Heart Association (low risk) Summary table Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size Intervention duration Compliance to sodium target (urinary data) Results Gillies et al. (1984), Australia [] study II Adults with moderate hypertension, some receiving medication (information on number of participants on Participants randomly allocated to on one of two cross-over arms: 1. Dietary advice for moderate dietary salt restriction Blood pressure (supine and standing), MAP Note: specific values for MAP not given in study, stated as having no 24 6 Salt restriction resulted in decrease from 169mmol/24hr (SEM: 13) to 92mmol/24hr (SEM: 7) – unclear if this change was from baseline or Mean difference between low sodium diet to normal sodium diet: Supine: SBP: -2.4mmHg (SEM: 2.51, CI: -7.32, 2.52) over
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