African and SBP: -4.80mmHg Caribbean pts. (SEM: 1.24, CI: -7.23, -2.37) Normal sodium period: 162 +59 DBP: (SEM: mmHg 0.67, CI: -3.51, -0.89) Low sodium period: 116 + 44 mmHg (p<0.001) Key features for bias assessment of randomised trials Citation Method of Allocation Blinding Loss to Use of Ceasing study Reporting Funding source randomisation concealment early for benefit all where outcome required results He et al. Low risk Low risk Participants: <10% loss to No (unclear risk) No (low risk) Yes (low UK Food (2009) (computer (computer low risk follow-up (low risk) Standards random generated random risk) Agency (low risk) Providers: low number) number, risk conducted by individuals not Outcome involved in the assessors: low conduct of the risk study)
African and Caribbean pts. Normal sodium period: 162 +59 mmHg Low sodium period: 116 + 44 mmHg (p<0.001) SBP: -4.80mmHg (SEM: 1.24, CI: -7.23, -2.37) DBP: (SEM: 0.67, CI: -3.51, -0.89) Key features for bias assessment of randomised trials Citation Method of randomisation Allocation concealment Blinding Loss to Use of where required Ceasing study early for benefit Reporting all outcome results Funding source He et al. (2009) Low risk (computer random number) Low risk (computer generated random number, conducted by individuals not involved in the conduct of the study) Participants: low risk Providers: low risk Outcome assessors: low risk <10% loss to follow-up (low risk) No (unclear risk) No (low risk) Yes (low risk) UK Food Standards Agency (low risk)
Sodium%20Supporting%20Document%201%20%20Systematic%20Literature%20Review.docx