With placement of Cefazolin Vancomycin (preferred)* Cefazolin prosthesis (if surgery 30 mg/kg IV (max: 2 g) at 15 mg/kg IV (max: 1 g) at induction of 30 mg/kg IV at induction of anesthesia involves traversing mucous induction of anesthesia anesthesia OR (if beta-lactam allergy) membranes, use regimen OR OR Vancomycin (preferred)* for clean contaminated as Clindamycin Clindamycin 15 mg/kg IV at induction of anesthesia above) 15 mg/kg IV (max: 600 15 mg/kg IV (max: 600 mg) at induction OR mg) at induction of of anesthesia Clindamycin anesthesia *25% S. aureus are resistant to 7.5 mg/kg IV at induction of anesthesia clindamycin *25% are resistant to clindamycin S. aureus Insertion of tissue Cefazolin Clindamycin Cefazolin expander 30 mg/kg IV (max: 2 g) at 15 mg/kg IV (max: 600 mg) at induction 30 mg/kg IV (max: 2 g) at induction of induction of anesthesia of anesthesia anesthesia OR if near oral cavity OR If near oral cavity Clindamycin Clindamycin 15 mg/kg IV (max: 600 7.5 mg/kg IV at induction of anesthesia mg) at induction of OR (if beta-lactam allergy) anesthesia Vancomycin (preferred)* 15 mg/kg IV at induction of anesthesia OR Clindamycin 7.5 mg/kg IV at induction of anesthesia (If near oral cavity, Clindamycin 7.5 mg/kg IV at induction of anesthesia) *25% S. aureus are resistant to clindamycin Pectus excavatum Cefazolin Vancomycin (preferred)* n/a 30 mg/kg IV (max: 2 g) at 15 mg/kg IV at induction of anesthesia induction of anesthesia OR Clindamycin 15 mg/kg IV (max: 600 mg) at induction of anesthesia *25% are resistant to S. aureus clindamycin
With placement of prosthesis (if surgery involves traversing mucous membranes, use regimen for clean contaminated as above) Cefazolin 30 mg/kg IV (max: 2 g) at induction of anesthesia OR Clindamycin 15 mg/kg IV (max: 600 mg) at induction of anesthesia Vancomycin (preferred)* 15 mg/kg IV (max: 1 g) at induction of anesthesia OR Clindamycin 15 mg/kg IV (max: 600 mg) at induction of anesthesia *25% S. aureus are resistant to clindamycin Cefazolin 30 mg/kg IV at induction of anesthesia OR (if beta-lactam allergy) Vancomycin (preferred)* 15 mg/kg IV at induction of anesthesia OR Clindamycin 7.5 mg/kg IV at induction of anesthesia *25% S. aureus are resistant to clindamycin Insertion of tissue expander Cefazolin 30 mg/kg IV (max: 2 g) at induction of anesthesia OR if near oral cavity Clindamycin 15 mg/kg IV (max: 600 mg) at induction of anesthesia Clindamycin 15 mg/kg IV (max: 600 mg) at induction of anesthesia Cefazolin 30 mg/kg IV (max: 2 g) at induction of anesthesia OR If near oral cavity Clindamycin 7.5 mg/kg IV at induction of anesthesia OR (if beta-lactam allergy) Vancomycin (preferred)* 15 mg/kg IV at induction of anesthesia OR Clindamycin 7.5 mg/kg IV at induction of anesthesia (If near oral cavity, Clindamycin 7.5 mg/kg IV at induction of anesthesia) *25% S. aureus are resistant to clindamycin Pectus excavatum Cefazolin 30 mg/kg IV (max: 2 g) at induction of anesthesia Vancomycin (preferred)* 15 mg/kg IV at induction of anesthesia OR Clindamycin 15 mg/kg IV (max: 600 mg) at induction of anesthesia *25% S. aureus are resistant to clindamycin n/a
SLA_2014_08_19_SO_1400863_SDC1.docx