Q1 What is the prevalence and incidence of pre-eclampsia, including population-specific groups Estimated prevalence and incidence of pre-eclampsia in cohort studies Study ref LoE N Aim/ methods Findings Comments III-2 5,784 Aim: To examine the effect of a combination There were 12 (0.4%) cases of early PE in () of screening and treatment with low-dose the observational cohort and one aspirin on the prevalence of early-onset (0.04%) in the interventional cohort (PE). (P<0.01). Among all women with PE delivering before 37 weeks, 25 (0.83%) Methods: Retrospective analysis of two were in the observational cohort and 10 consecutive cohorts of women screened for (0.37%) in the interventional cohort early PE. The first was observed to determine (P=0.03). whether algorithms developed to screen for PE at 11 to 13+6 weeks gestation could be applied to our population. High-risk women in the second cohort were offered aspirin (150mg at night), with treatment starting immediately after screening. The prevalence of early PE and the proportion of women with PE delivering at 34-37 weeks' gestation were compared. III-2 3,014 Aim: to validate the Fetal Medicine Of women who had a live birth, 12 were () Foundation (FMF) multiple logistic regression delivered before 34 weeks due to early algorithm for prediction of risk of pre-eclampsia (0.4%) and 71 (2.4%) due in an Australian population. to late pre-eclampsia (after 34 weeks). Methods: All women who attended first trimester screening were assessed. After delivery, risks of early-onset (delivery prior to 34 weeks) pre-eclampsia, late pre-eclampsia and gestational hypertension were calculated using the FMF risk algorithm.
Q1 What is the prevalence and incidence of pre-eclampsia, including population-specific groups Estimated prevalence and incidence of pre-eclampsia in cohort studies Study ref LoE N Aim/ methods Findings Comments () III-2 5,784 Aim: To examine the effect of a combination of screening and treatment with low-dose aspirin on the prevalence of early-onset (PE). Methods: Retrospective analysis of two consecutive cohorts of women screened for early PE. The first was observed to determine whether algorithms developed to screen for PE at 11 to 13+6 weeks gestation could be applied to our population. High-risk women in the second cohort were offered aspirin (150mg at night), with treatment starting immediately after screening. The prevalence of early PE and the proportion of women with PE delivering at 34-37 weeks' gestation were compared. There were 12 (0.4%) cases of early PE in the observational cohort and one (0.04%) in the interventional cohort (P<0.01). Among all women with PE delivering before 37 weeks, 25 (0.83%) were in the observational cohort and 10 (0.37%) in the interventional cohort (P=0.03). () III-2 3,014 Aim: to validate the Fetal Medicine Foundation (FMF) multiple logistic regression algorithm for prediction of risk of in an Australian population. Methods: All women who attended first trimester screening were assessed. After delivery, risks of early-onset (delivery prior to 34 weeks) pre-eclampsia, late pre-eclampsia and gestational hypertension were calculated using the FMF risk algorithm. Of women who had a live birth, 12 were delivered before 34 weeks due to early pre-eclampsia (0.4%) and 71 (2.4%) due to late pre-eclampsia (after 34 weeks).
Preeclampsia%20evaluation%20report%2016May17.docx