Decision — Aim: to identify whether and under Under baseline assumptions, universal Compared with an initial () analytic what circumstances transabdominal transvaginal was the dominant TAUS screen, universal model ultrasound (TAUS) would be strategy. In comparison to TAUS, transvaginal ultrasound effective. universal transvaginal CL screening was a more cost-effective reduced preterm birth by 0.03%, strategy under most Methods: we compared an initial TAUS reduced costs by $1.2 million and assumptions. Optimizing CL screening approach with universal increased quality-adjusted life years TAUS testing transvaginal screening in a by 70 per 100,000 women. Although characteristics or applying hypothetical cohort of women with a robust to many changes in many a transabdominal singleton pregnancy. Cost, probability, estimates, the model was sensitive to screening strategy in lower and utility estimates were derived from the cost of a transvaginal ultrasound, risk populations may yield the existing literature. the prevalence of a short cervix and an initial TAUS to be the test characteristics (ie, sensitivity and specificity) of a TAUS screening examination for short CL.
() Decision analytic model — Aim: to identify whether and under what circumstances transabdominal ultrasound (TAUS) would be Methods: we compared an initial TAUS CL screening approach with universal transvaginal screening in a hypothetical cohort of women with a singleton pregnancy. Cost, probability, and utility estimates were derived from the existing literature. Under baseline assumptions, universal transvaginal was the dominant strategy. In comparison to TAUS, universal transvaginal CL screening reduced preterm birth by 0.03%, reduced costs by $1.2 million and increased quality-adjusted life years by 70 per 100,000 women. Although robust to many changes in many estimates, the model was sensitive to the cost of a transvaginal ultrasound, the prevalence of a short cervix and the test characteristics (ie, sensitivity and specificity) of a TAUS screening examination for short CL. Compared with an initial TAUS screen, universal transvaginal ultrasound was a more cost-effective strategy under most assumptions. Optimizing TAUS testing characteristics or applying a transabdominal screening strategy in lower risk populations may yield an initial TAUS to be effective.
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