Q6. How does each MFR identify and display outliers in their images. Should QIBA specify a standard handling? [Section 3.7] Q7. ROI location in most homogenous region of SWS color map? [Should this be a closed issue – if agreed upon or is there a way to decrease variability amongst users]. Q. ROI Size - If user selected – how big? (size of homogenous region versus variance) Q. DICOM conformance – Are new header fields needed? Q. Number of values averaged for each pixel in the color image. [Image reconstruction section of Profile] Q. Color Maps – Should these be QIBA specified? Color scale and number of colors in the map. Q. Give stiffness in m/sec or kPa? Closed Issues: The following issues have been considered closed by the biomarker committee. They are provided here to forestall discussion of issues that have already been raised and resolved, and to provide a record of the rationale behind the resolution. Q. At what point in the respiratory cycle should acquisition occur? A. Suspended tidal respiration (references needed) Q. Should the patient fast prior to acquisition? A. At least 3 hours prior to acquisition (references needed) Q. Does Steatosis affect assessment of liver fibrosis using elastography A. No. [References: End of Document] Q. How to best acquire from patients where intercostal approach is not feasible (narrow intercostal spacing, COPD)? If intercostal approach is unavailable, we recommend excluding the patient. [Consider MRE].
Q6. How does each MFR identify and display outliers in their images. Should QIBA specify a standard handling? [Section 3.7] Q7. ROI location in most homogenous region of SWS color map? [Should this be a closed issue – if agreed upon or is there a way to decrease variability amongst users]. Q. ROI Size - If user selected – how big? (size of homogenous region versus variance) Q. DICOM conformance – Are new header fields needed? Q. Number of values averaged for each pixel in the color image. [Image reconstruction section of Profile] Q. Color Maps – Should these be QIBA specified? Color scale and number of colors in the map. Q. Give stiffness in m/sec or kPa? Closed Issues: The following issues have been considered closed by the biomarker committee. They are provided here to forestall discussion of issues that have already been raised and resolved, and to provide a record of the rationale behind the resolution. Q. At what point in the respiratory cycle should acquisition occur? A. Suspended tidal respiration (references needed) Q. Should the patient fast prior to acquisition? A. At least 3 hours prior to acquisition (references needed) Q. Does Steatosis affect assessment of liver fibrosis using elastography A. No. [References: End of Document] Q. How to best acquire from patients where intercostal approach is not feasible (narrow intercostal spacing, COPD)? If intercostal approach is unavailable, we recommend excluding the patient. [Consider MRE].
QIBA_Profile_04112016_BSG_Edited_discussed_with_MD4-10-16.docx