I 39 studies Aim: to outline the evidence on the risk of preterm Depression — in studies with a low risk of bias OR () associated with antenatal depression, anxiety, and stress. ranged from 1.13 to 3.93 with narrow confidence intervals. One study found no clear link between Methods: Four electronic database searches were major depressive episode and PTB but a conducted to identify quantitative population-based, significant increase in risk for PTB with multi-centre, cohort studies and randomised-controlled antidepressant use (OR = 2.1 [95%CI 1.0–4.6]). trial studies focusing on the association between antenatal depression, anxiety, and stress, and preterm Anxiety — three of four studies found a birth published in English between 1980 and 2013. significant association, with OR ranging from 1.48 to 2.73. Perceived stress — five studies consistently demonstrated a statistically significant relationship. Of the three studies with low risk of bias two demonstrated increased risk from OR 1.14 to RR 1.75. {Ding, 2014 I 12 studies To investigate the association between maternal anxiety Maternal anxiety during pregnancy was #1375} and preterm birth(PTB)and/or low birthweight(LBW). associated with significant increased risk of PTB 17,304 to Literature was searched until June 2013. Only prospective (pooled RR 1.50, 95%CI 1.33 1.70). women cohort studies that reported data on maternal anxiety during pregnancy with PTB and/or LBW were included. Pooled relative risks (RRs) with 95% confidence intervals fixed (CIs) were calculated using or random effects models depending on the size of heterogeneity. I 25 studies Aim: to provide a summary of the published evidence of The odds ratio for prenatal maternal anxiety was () the relationship between prenatal maternal anxiety and 1.70 (95%CI 1.33 to 2.18) for PTB and 1.67 (95%CI PTB while examining methodological and statistical 1.35 to 2.07) for spontaneous PTB comparing sources of heterogeneity. higher levels of anxiety to lower levels. Methods. Published studies from MEDLINE, CINAHL, PsycINFO, and EMBASE, until June 2015, were extracted and reviewed.
() I 39 studies Aim: to outline the evidence on the risk of preterm associated with antenatal depression, anxiety, and stress. Methods: Four electronic database searches were conducted to identify quantitative population-based, multi-centre, cohort studies and randomised-controlled trial studies focusing on the association between antenatal depression, anxiety, and stress, and preterm birth published in English between 1980 and 2013. Depression — in studies with a low risk of bias OR ranged from 1.13 to 3.93 with narrow confidence intervals. One study found no clear link between major depressive episode and PTB but a significant increase in risk for PTB with antidepressant use (OR = 2.1 [95%CI 1.0–4.6]). Anxiety — three of four studies found a significant association, with OR ranging from 1.48 to 2.73. Perceived stress — five studies consistently demonstrated a statistically significant relationship. Of the three studies with low risk of bias two demonstrated increased risk from OR 1.14 to RR 1.75. {Ding, 2014 #1375} I 12 studies 17,304 women To investigate the association between maternal anxiety and preterm birth(PTB)and/or low birthweight(LBW). Literature was searched until June 2013. Only prospective cohort studies that reported data on maternal anxiety during pregnancy with PTB and/or LBW were included. Pooled relative risks (RRs) with 95% confidence intervals (CIs) were calculated using fixed or random effects models depending on the size of heterogeneity. Maternal anxiety during pregnancy was associated with significant increased risk of PTB (pooled RR 1.50, 95%CI 1.33 to 1.70). () I 25 studies Aim: to provide a summary of the published evidence of the relationship between prenatal maternal anxiety and PTB while examining methodological and statistical sources of heterogeneity. Methods. Published studies from MEDLINE, CINAHL, PsycINFO, and EMBASE, until June 2015, were extracted and reviewed. The odds ratio for prenatal maternal anxiety was 1.70 (95%CI 1.33 to 2.18) for PTB and 1.67 (95%CI 1.35 to 2.07) for spontaneous PTB comparing higher levels of anxiety to lower levels.
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