Drug Recommended Dose Comments Hyoscine Butylbromide For colic: Useful for spasm of smooth 60mg – 120mg / 24 hours muscle (gastro-intestinal and Do not confuse with (higher doses sometimes used) ureteric colic) Hyoscine Hydrobromide Used to dry up noisy Usual starting dose 60mg respiratory secretions Available as: - Less likely to cause CNS 20mg / ml ampoules effects (including sedation) For respiratory secretions: than Hyoscine Hydrobromide 20mg – 60mg / 24 hours Acceptable combinations in syringe based on laboratory data and clinical practice at recommended doses and concentrations: 3 Drugs Hyoscine Butylbromide + Diamorphine + Levomepromazine or + Midazolam 2 Drugs Hyoscine Butylbromide + Diamorphine or + Haloperidol + Midazolam 7.9
Drug Recommended Dose Comments Hyoscine Butylbromide Do not confuse with Hyoscine Hydrobromide Available as: - 20mg / ml ampoules For colic: 60mg – 120mg / 24 hours (higher doses sometimes used) Usual starting dose 60mg For respiratory secretions: 20mg – 60mg / 24 hours Useful for spasm of smooth muscle (gastro-intestinal and ureteric colic) Used to dry up noisy respiratory secretions Less likely to cause CNS effects (including sedation) than Hyoscine Hydrobromide Acceptable combinations in syringe based on laboratory data and clinical practice at recommended doses and concentrations: 3 Drugs Hyoscine Butylbromide + Diamorphine + Levomepromazine or + Midazolam 2 Drugs Hyoscine Butylbromide + Diamorphine or + Haloperidol + Midazolam 7.9
procedure_for_the_use_of_the_syringe_pump_in_palliative_and_end_of_life_care1.docx