Arterial stiffness I 23 studies Aim: to investigate the association between A significant increase in all arterial () preeclampsia and arterial stiffness. stiffness indices combined was observed in women with preeclampsia Method: A systematic review and vs women with normotensive was conducted using MEDLINE, pregnancies [SMD 1.62, 95%CI 0.73 to EMBASE, and the Cochrane Library. 2.50]; carotid-femoral pulse wave velocity (cfPWV) and augmentation index (AIx) were also significantly increased (WMD cfPWV 1.04, 95%CI 0.34 to 1.74; WMD AIx 15.10, 95%CI 5.08 to 25.11), whereas carotid-radial PWV (crPWV) increase did not reach significance (WMD crPWV 0.99, 95%CI 0.07 to 2.05). Periodontal disease Study ref LoE N Aim/ methods Findings Comments I 15 studies (13 Aim: to ascertain the relationship between Based on a random-effects () case-control; PD and preeclampsia. a significant association 2 cohort) between PD and preeclampsia was Methods: The PubMed database was identified (OR 2.79, 95% CI 2.01 to 3.01, 1,089 women searched up to January 12, 2013, for relevant P<0.0001). Although the causality with observational studies on an association remains unclear, the association between PD and the risk of preeclampsia. between PD and preeclampsia may Data were extracted and analyzed reflect the induction of PD by the independently by two authors. The preeclamptic state, or it may be part of was performed using comprehensive an overall exaggerated inflammatory meta-analysis software. response to pregnancy.
Arterial stiffness () I 23 studies Aim: to investigate the association between preeclampsia and arterial stiffness. Method: A systematic review and was conducted using MEDLINE, EMBASE, and the Cochrane Library. A significant increase in all arterial stiffness indices combined was observed in women with preeclampsia vs women with normotensive pregnancies [SMD 1.62, 95%CI 0.73 to 2.50]; carotid-femoral pulse wave velocity (cfPWV) and augmentation index (AIx) were also significantly increased (WMD cfPWV 1.04, 95%CI 0.34 to 1.74; WMD AIx 15.10, 95%CI 5.08 to 25.11), whereas carotid-radial PWV (crPWV) increase did not reach significance (WMD crPWV 0.99, 95%CI to 2.05). Periodontal disease Study ref LoE N Aim/ methods Findings Comments () I 15 studies (13 case-control; 2 cohort) 1,089 women with Aim: to ascertain the relationship between PD and preeclampsia. Methods: The PubMed database was searched up to January 12, 2013, for relevant observational studies on an association between PD and the risk of preeclampsia. Data were extracted and analyzed independently by two authors. The was performed using comprehensive meta-analysis software. Based on a random-effects a significant association between PD and preeclampsia was identified (OR 2.79, 95% CI 2.01 to 3.01, P<0.0001). Although the causality remains unclear, the association between PD and preeclampsia may reflect the induction of PD by the preeclamptic state, or it may be part of an overall exaggerated inflammatory response to pregnancy. 0.07
Preeclampsia%20evaluation%20report%2016May17.docx