Genetically Modified Organisms (Contained Use) Regulations 2014 (as amended) Control of Substances Hazardous to Health Regulations 2002 (as amended) Containment Level 3 Inspection Checklist For genetically modified micro-organisms (assigned to GM Class 3) and/or wild type pathogens (ACDP Hazard Group 3) Laboratory: Date of Inspection: This checklist is based on COSHH (bold), GMO (CU) Regulations, Dangerous Goods Transport and Biosecurity legislation, in order to conduct inspections of biological / GM Agent work at Containment Level 3 (CL3). Bullet points are added where ACDP / SACGM / HSE guidance recommends specific practical actions and key Industry Standards are referred to where applicable. There may be other H&S Regulations applicable to the work and other QMUL Policies / Guidance and checklists should also be utilised as required during inspections. This checklist can also be used as a ‘guide’ for CL3 facility planning, design and commissioning and must be used in conjunction with the detailed ACDP / SACGM, HSE requirements, QMUL Standards and relevant Industry / Sector Standards. No. Requirement Achieved Comments GMO CU BIOLOGICAL CONTAINMENT YES NO Reg 18 Sch MEASURES AND SAFETY (or 8/ ARRANGEMENTS N/A) COSHH Sch 3 or Reg LABORATORY M1 / Part Isolation from other areas in the II 1 building (required) (M1) Adequate spacing for staff and work undertaken (guidance) M2 / Part Sealable for fumigation – II 4 validated (required) Guidance Periodic checks for dust trails conducted e.g. visual, smoke – pencil test M14 / Laboratory proofed against Part II 7 disease vectors ( e.g. rodents, arthropods) (required) M19 / Observation window or Part II 11 alternative mechanism for viewing all occupants (required) M 4 / Entry to lab via airlock (required Guidance if the risk assessment shows) or lobby area (guidance) M5 / Part Maintain laboratory at negative II 6 pressure to atmosphere (required) Guidance Control panel for air handling
Genetically Modified Organisms (Contained Use) Regulations 2014 (as amended) Control of Substances Hazardous to Health Regulations 2002 (as amended) Containment Level 3 Inspection Checklist For genetically modified micro-organisms (assigned to GM Class 3) and/or wild type pathogens (ACDP Hazard Group 3) Laboratory: Date of Inspection: This checklist is based on COSHH (bold), GMO (CU) Regulations, Dangerous Goods Transport and Biosecurity legislation, in order to conduct inspections of biological / GM Agent work at Containment Level 3 (CL3). Bullet points are added where ACDP / SACGM / HSE guidance recommends specific practical actions and key Industry Standards are referred to where applicable. There may be other H&S Regulations applicable to the work and other QMUL Policies / Guidance and checklists should also be utilised as required during inspections. This checklist can also be used as a ‘guide’ for CL3 facility planning, design and commissioning and must be used in conjunction with the detailed ACDP / SACGM, HSE requirements, QMUL Standards and relevant Industry / Sector Standards. No. Requirement Achieved Comments GMO CU Reg 18 Sch 8/ COSHH Sch 3 or Reg BIOLOGICAL CONTAINMENT MEASURES AND SAFETY ARRANGEMENTS YES (or N/A) NO LABORATORY M1 / Part II 1 Isolation from other areas in the building (required) (M1) Adequate spacing for staff and work undertaken (guidance) M2 / Part II 4 Guidance Sealable for fumigation – validated (required) Periodic checks for dust trails conducted – e.g. visual, smoke pencil test M14 / Part II 7 Laboratory proofed against disease vectors ( e.g. rodents, arthropods) (required) M19 / Part II 11 Observation window or alternative mechanism for viewing all occupants (required) M 4 / Guidance Entry to lab via airlock (required if the risk assessment shows) or lobby area (guidance) M5 / Part II 6 Guidance Maintain laboratory at negative pressure to atmosphere (required) Control panel for air handling
QMUL_HS_095_March-2016_Containment-Level-3-Inspection-Checklist.docx