Response was defined as when any follow-up symptom value was equal to 0. Patients who continued to have 0 symptoms throughout the follow-up period were defined as a sustained response. Overall response to treatment for adjustment disorder participants was 33-100% and sustained response over 4 months was achieved for 33-100% of patients. No specific SSRI was found to be more effective than any other. Özten et Case Psychiatric 100% Pharmacotherapy Sertraline (SSRI) Sertraline (25 mg/day Hamilton N = 1 al. (2015) study patient adjustment started and 50 mg/day) for a Depression – disorder with discontinued due to week, then fluoxetine Rating Scale Age: 34 years side effects; (20m/g day) for 7 (HDRS) Female Fluoxetine (SSRI) weeks Hamilton mood started and Anxiety maintained + Rating Scale Stressor: Couples (HAS) Interpersonal psychotherapy Beck Depression Inventory (BDI) Pre-treatment scores were 18 (HDRS); 12 (HAS); and 24 (BDI), after 2 months of treatment scores had dropped to 11, 6, and 9. Pharmacotherapy Anxious symptoms – Nguyen et RCT with French 100% Pharmacotherapy Intervention: Intervention: 150 Hamilton N = 191 al. (2006) 1 week outpatients adjustment Etifoxine mg/day for 28 days Anxiety follow-up seeing GPs disorder with
Response was defined as when any follow-up symptom value was equal to 0. Patients who continued to have 0 symptoms throughout the follow-up period were defined as a sustained response. Overall response to treatment for adjustment disorder participants was 33-100% and sustained response over 4 months was achieved for 33-100% of patients. No specific SSRI was found to be more effective than any other. Özten et al. (2015) Case study Psychiatric patient Age: 34 years Female 100% adjustment disorder with mood Stressor: Interpersonal Pharmacotherapy Sertraline (SSRI) started and discontinued due to side effects; Fluoxetine (SSRI) started and maintained + Couples psychotherapy Sertraline (25 mg/day – 50 mg/day) for a week, then fluoxetine (20m/g day) for 7 weeks Hamilton Depression Rating Scale (HDRS) Hamilton Anxiety Rating Scale (HAS) Beck Depression Inventory (BDI) N = 1 Pre-treatment scores were 18 (HDRS); 12 (HAS); and 24 (BDI), after 2 months of treatment scores had dropped to 11, 6, and 9. Pharmacotherapy – Anxious symptoms Nguyen et al. (2006) RCT with 1 week follow-up French outpatients seeing GPs 100% adjustment disorder with Pharmacotherapy Intervention: Etifoxine Intervention: 150 mg/day for 28 days Hamilton Anxiety N = 191
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