III-2 2,261 Aim: to investigate whether multivitamin use Body mass index (BMI)>25 was () during pregnancy is associated with a associated with increased in reduced risk of pre-eclampsia. risk (OR 1.97; 95%CI 0.93 to 4.16). First trimester multivitamin use was Methods: The effect of multivitamin use on associated with a 67% reduction in incidence of pre-eclampsia in lean and risk (95%CI: 0.14 to 0.75). overweight/obese women was analysed Stratification by BMI demonstrated a using data collected between 2006 and 2011 55% reduction in pre-eclampsia risk as part of the Environments for Healthy Living (95%CI: 0.30 to 0.86) in overweight (BMI: Project, Griffith University, Australia. 25-29.9) and 62% risk reduction (95%CI: 0.16, 0.92) in obese (BMI:>30) cohorts that supplemented with multivitamins in the first trimester of pregnancy. First trimester folate supplementation demonstrated significance upon stratification by overweight status for women with BMI >25 (AOR 0.55 95%CI: 0.31 to 0.96). Women aged 45 years or older Study ref LoE N Aim/ methods Findings Comments III-2 49,126 Aim: to determine maternal and perinatal There was weak evidence for an () outcomes of pregnancies in women aged 45 increased risk of pre-eclampsia (OR years or older compared to women aged 1.86; 95% 0.9 to 3.6; p=0.052). years. Methods: Data on births at 20 or more weeks' gestation were obtained from the Victorian Perinatal Data Collection for the years 2005 and 2006 and selected maternal and perinatal outcomes for women of very advanced maternal age (VAMA) aged 45 years or older (n=217) compared to women aged 30-34 years (n=48,909).
() III-2 2,261 Aim: to investigate whether multivitamin use during pregnancy is associated with a reduced risk of pre-eclampsia. Methods: The effect of multivitamin use on incidence of pre-eclampsia in lean and overweight/obese women was analysed using data collected between 2006 and 2011 as part of the Environments for Healthy Living Project, Griffith University, Australia. Body mass index (BMI)>25 was associated with increased in risk (OR 1.97; 95%CI 0.93 to 4.16). First trimester multivitamin use was associated with a 67% reduction in risk (95%CI: 0.14 to 0.75). Stratification by BMI demonstrated a 55% reduction in pre-eclampsia risk (95%CI: 0.30 to 0.86) in overweight (BMI: 25-29.9) and 62% risk reduction (95%CI: 0.16, 0.92) in obese (BMI:>30) cohorts that supplemented with multivitamins in the first trimester of pregnancy. First trimester folate supplementation demonstrated significance upon stratification by overweight status for women with BMI >25 (AOR 0.55 95%CI: 0.31 to 0.96). Women aged 45 years or older Study ref LoE N Aim/ methods Findings Comments () III-2 49,126 Aim: to determine maternal and perinatal outcomes of pregnancies in women aged 45 years or older compared to women aged years. Methods: Data on births at 20 or more weeks' gestation were obtained from the Victorian Perinatal Data Collection for the years 2005 and 2006 and selected maternal and perinatal outcomes for women of very advanced maternal age (VAMA) aged 45 years or older (n=217) compared to women aged 30-34 years (n=48,909). There was weak evidence for an increased risk of pre-eclampsia (OR 1.86; 95% 0.9 to 3.6; p=0.052).
Preeclampsia%20evaluation%20report%2016May17.docx