Supplementary material Supplementary 1. Notations. Let us consider two drugs A and B in combination. the dose of drug A administered the dose of drug B administered the effect of drug A at dose the effect of drug B at dose the effect of the combination of doses and the single dose of drug A reaching the combination effect the single dose of drug B reaching the combination effect the maximum effect of drug A the maximum effect of drug B the half maximum effective dose of drug A The half maximum effective dose of drug B
Supplementary material Supplementary 1. Notations. Let us consider two drugs A and B in combination. the dose of drug A administered the dose of drug B administered the effect of drug A at dose the effect of drug B at dose the effect of the combination of doses and the single dose of drug A reaching the combination effect the single dose of drug B reaching the combination effect the maximum effect of drug A the maximum effect of drug B the half maximum effective dose of drug A The half maximum effective dose of drug B
prp20003-e00149-sd1.docx