Phase 1 We will recruit 30 healthy volunteers that do not complain of any smell disorders and ask them to perform the identification part of the Sniffin’ Sticks test. This involves 16 odours being presented in turn and for each odour the subject must choose from 1 of 4 options (see table below – correct answers in bold). This takes approximately 5 minutes. The healthy volunteers will attend a research clinic once only to have their sense of smell assessed. We will also use the internal email system to invite potential volunteers from within hospital staff to participate. Outpatient attendants for non-rhinological conditions will also be invited to take part. 1 orange blackberry strawberry pineapple 2 smoke leather glue grass 3 honey vanilla chocolate cinnamon 4 chives peppermint wood onion 5 coconut banana walnut cherry 6 peach apple lemon grapefruit 7 liquorice gummibears chewing gum cookies 8 mustard rubber menthol turpentine 9 onion sauerkraut garlic carrot 10 cigarette coffee wine candle smoke 11 melon peach orange apple 12 cloves pepper cinnamon mustard 13 pear plum peach pineapple 14 camomile raspberry rose cherry 15 aniseed rum honey wood 16 bread fish cheese ham The responses will then be analysed to look for any unfamiliarity with the descriptors (alternative options). The test will then be revised as necessary to produce a British version of the test. It is expected that this will simply involve changing some of the descriptors for the alternative answers above. Phase 2 The adapted UK version of the Sniffin’ Sticks will be tested on 30 healthy volunteers for validation purposes allowing comparison with the original German version. This will be a repeat process of phase 1. Patients attending the Smell & Taste Clinic will also be invited to participate in the study. The olfactory testing is part of their routine assessment and will not represent a deviation from clinical practice. These patients are also asked to complete the olfactory disorders questionnaire routinely, but this is as yet unvalidated although it is based on one produced in Germany by Frasnelli and Hummel. One hundred patients attending the clinic will therefore be consented for use of their smell test and questionnaire data as part of this study. In order that potential volunteers will have sufficient time to read the patient information sheet, this will be posted to them along with their appointment letter for the clinic. Previous clinic visitors will also be invited by making the consent form and PIS available
Phase 1 We will recruit 30 healthy volunteers that do not complain of any smell disorders and ask them to perform the identification part of the Sniffin’ Sticks test. This involves 16 odours being presented in turn and for each odour the subject must choose from 1 of 4 options (see table below – correct answers in bold). This takes approximately 5 minutes. The healthy volunteers will attend a research clinic once only to have their sense of smell assessed. We will also use the internal email system to invite potential volunteers from within hospital staff to participate. Outpatient attendants for non-rhinological conditions will also be invited to take part. 1 orange blackberry strawberry pineapple 2 smoke leather glue grass 3 honey vanilla chocolate cinnamon 4 chives peppermint wood onion 5 coconut banana walnut cherry 6 peach apple lemon grapefruit 7 liquorice gummibears chewing gum cookies 8 mustard rubber menthol turpentine 9 onion sauerkraut garlic carrot 10 cigarette coffee wine candle smoke 11 melon peach orange apple 12 cloves pepper cinnamon mustard 13 pear plum peach pineapple 14 camomile raspberry rose cherry 15 aniseed rum honey wood 16 bread fish cheese ham The responses will then be analysed to look for any unfamiliarity with the descriptors (alternative options). The test will then be revised as necessary to produce a British version of the test. It is expected that this will simply involve changing some of the descriptors for the alternative answers above. Phase 2 The adapted UK version of the Sniffin’ Sticks will be tested on 30 healthy volunteers for validation purposes allowing comparison with the original German version. This will be a repeat process of phase 1. Patients attending the Smell & Taste Clinic will also be invited to participate in the study. The olfactory testing is part of their routine assessment and will not represent a deviation from clinical practice. These patients are also asked to complete the olfactory disorders questionnaire routinely, but this is as yet unvalidated although it is based on one produced in Germany by Frasnelli and Hummel. One hundred patients attending the clinic will therefore be consented for use of their smell test and questionnaire data as part of this study. In order that potential volunteers will have sufficient time to read the patient information sheet, this will be posted to them along with their appointment letter for the clinic. Previous clinic visitors will also be invited by making the consent form and PIS available
Protocol+validation+of+sniffin+sticks+1.4+(22.12.2014).docx