Table S1 Characteristics of Included Studies Study Population Resting Cardiac Treatments Physical Description of Exercise and Hypertension Abnormalities Activity Exercise Hypertension Quality of Evidence Agnoletti et al., N = 8 N = 8 VSD, N = 3 8 Direct suture Not reported 30 Exercise 2 SBP >270 Adults 5 9 Extended stress tests mmHg Grade: 3A and 7 on of Reconstruction 15 7 SBP >250 Quality: 10 Children Great 3 Banding of 15 mmHg 7-29 treatment Arteries, N Pulmonary Trunk Mean 22 9 “Mild” years = 1 3 De-banding months 5 “Severe” Mean 17 2 VSD Closure post-surgery 3 adults years 1 Synthetic Patch Treadmill SBP >250 1 Arterial Switch Bruce mmHg Operation protocol 13 children Exercise SBP >95th terminated: percentile 1 claudication of legs, 2 exercise Balderston et N = 31 Aortic 8 Subclavian Flap VO2max 27 Exercise N = 6 “usually al., 19923 Children normal” Repair 48 ± 1 stress tests 3A 7-17 Resting N = 21 End to End Mean 93 Quality: 9 years SBP 111 ± 24 Anastomosis months Mean 11 4.7 mmHg Aortic 1 Patch Aortoplasty post-surgery years 1 Tubular Graft Treadmill with VSD 6 Recurrent Bruce or AS, N = Obstruction Repair protocol 7 4 Aortic or SubAS Repair
Table S1 Characteristics of Included Studies Study and Quality of Evidence Population Resting Hypertension Cardiac Abnormalities Treatments Physical Activity Description of Exercise Exercise Hypertension Agnoletti et al., Grade: 3A Quality: 10 N = 8 Adults and 7 Children 7-29 years Mean 17 years N = 8 5 treatment VSD, N = 3 of Great Arteries, N = 1 8 Direct suture 9 Extended Reconstruction 3 Banding of Pulmonary Trunk 3 De-banding 2 VSD Closure 1 Synthetic Patch 1 Arterial Switch Operation Not reported 30 Exercise stress tests 15 15 Mean 22 months post-surgery Treadmill Bruce protocol Exercise terminated: 1 claudication of legs, 2 exercise 2 SBP >270 mmHg 7 SBP >250 mmHg 9 “Mild” 5 “Severe” 3 adults SBP >250 mmHg 13 children SBP >95th Balderston et al., 19923 3A Quality: 9 N = 31 Children 7-17 years Mean 11 years “usually normal” Resting SBP 111 ± 4.7 mmHg Aortic N = 24 Aortic with VSD or AS, N = 7 8 Subclavian Flap Repair 21 End to End Anastomosis 1 Patch Aortoplasty 1 Tubular Graft 6 Recurrent Obstruction Repair 4 Aortic or SubAS Repair VO2max 48 ± 1 27 Exercise stress tests Mean 93 months post-surgery Treadmill Bruce protocol N = 6 percentile on
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