The Genetics Revolution 3 CHAPTER 1 Which of three major groups (domains) of life in Figure 1-11 is not represented by a model organism? Answer: Archaea Figure 1-13b the human chromosomes in a single cell. The green dots show the location of a gene called Is the cell in this figure a sex cell (gamete)? Explain your answer. BAPX1. Answer: It is not a sex cell. Cloned gene has hybridized to two chromosomes in the cell, BAPXI indicating there are two copies of the gene. If it were a gamete, it would have only one BAPXI copy of each chromosome and of the gene. BAPXI Figure 1-15 shows the family tree or pedigree for Louise Benge (Individual VI-1) who suffers from the disease ACDC because she has two mutant copies of the gene. She has four CD73 siblings (VI- 2, VI-3, VI-4, and VI-5) who have this disease for the same reason. Do all the 10 children of Louise and her siblings have the same number of mutant copies of the gene, or CD73 might this number be different for some of the 10 children? Answer: All 10 children have one mutant copy of the gene. Children get one copy CD73 CD73 from mom and one from their dad. Since Louise and her four siblings each carry two defective genes, all their children will get one mutant copy. CD73 BASIC QUESTIONS Below is the sequence of a single strand of a short DNA molecule. On a piece of paper, rewrite this sequence and then write the sequence of the complementary strand below it. GTTCGCGGCCGCGAAC Comparing the top and bottom strands, what do you notice the relationship between them? Answer: GTTCGCGGCCGCGAAC CAAGCGCCGGCGCTTG They are complementary to each other and run in the opposite direction (antiparallel). The sequences are also palindromic; they read the same in either direction. Mendel studied a variety of pea plants with stems that are 20 cm long and a variety with tall dwarf stems that are only 12 cm long. Under blending theory, how long would you expect the stems of first and second hybrids to be? Under Mendelian rules, what would you expect to observe in the second-generation hybrids if all the first-generation hybrids were tall?
CHAPTER 1 The Genetics Revolution 3 Which of three major groups (domains) of life in Figure 1-11 is not represented by a model organism? Answer: Archaea Figure 1-13b the human chromosomes in a single cell. The green dots show the location of a gene called BAPX1. Is the cell in this figure a sex cell (gamete)? Explain your answer. Answer: It is not a sex cell. Cloned BAPXI gene has hybridized to two chromosomes in the cell, indicating there are two copies of the BAPXI gene. If it were a gamete, it would have only one copy of each chromosome and of the BAPXI gene. Figure 1-15 shows the family tree or pedigree for Louise Benge (Individual VI-1) who suffers from the disease ACDC because she has two mutant copies of the CD73 gene. She has four siblings (VI- 2, VI-3, VI-4, and VI-5) who have this disease for the same reason. Do all the 10 children of Louise and her siblings have the same number of mutant copies of the CD73 gene, or might this number be different for some of the 10 children? Answer: All 10 children have one mutant copy of the CD73 gene. Children get one CD73 copy from mom and one from their dad. Since Louise and her four siblings each carry two defective genes, all their children will get one mutant CD73 copy. BASIC QUESTIONS Below is the sequence of a single strand of a short DNA molecule. On a piece of paper, rewrite this sequence and then write the sequence of the complementary strand below it. GTTCGCGGCCGCGAAC Comparing the top and bottom strands, what do you notice the relationship between them? Answer: GTTCGCGGCCGCGAAC CAAGCGCCGGCGCTTG They are complementary to each other and run in the opposite direction (antiparallel). The sequences are also palindromic; they read the same in either direction. Mendel studied a tall variety of pea plants with stems that are 20 cm long and a dwarf variety with stems that are only 12 cm long. Under blending theory, how long would you expect the stems of first and second hybrids to be? Under Mendelian rules, what would you expect to observe in the second-generation hybrids if all the first-generation hybrids were tall?
IGA_11e_SM_Ch_01.docx