Results of the dissolution of aspirin tablets: (Bayer tablets, 300 mg) Dilution factor = Abs. Time ( total vol / vol Conc. = x dil factor x 5 at 265 % released =x 100 (min) taken from the (mg/500ml) nm sample) 5 10 15 20 25 30 45 Results of the dissolution of aspirin Micronized: ( ) Dilution factor = Abs. Time ( total vol / vol Conc. = x dil factor x 5 at 265 % released =x 100 (min) taken from the (mg/500ml) nm sample) 5 10 15 20 25 30 45 Plot the Time versus % release on graph paper and comment on the effect of the particle size on the drug released rate?? Determine the t80% of the drug?? Comment on the release of the drug from the products at 30 minute according to USP requirements
Results of the dissolution of aspirin tablets: (Bayer tablets, 300 mg) Time (min) Abs. at 265 nm Dilution factor = ( total vol / vol taken from the sample) Conc. = x dil factor x 5 (mg/500ml) % released =x 100 5 10 15 20 25 30 45 Results of the dissolution of aspirin Micronized: ( ) Time (min) Abs. at 265 nm Dilution factor = ( total vol / vol taken from the sample) Conc. = x dil factor x 5 (mg/500ml) % released =x 100 5 10 15 20 25 30 45 Plot the Time versus % release on graph paper and comment on the effect of the particle size on the drug released rate?? Determine the t80% of the drug?? Comment on the release of the drug from the products at 30 minute according to USP requirements
pht_414.docx