Results of the dissolution of paracetamol tablets Official Test: Dilution factor = Conc. =[(abs-a)/b]x dil factor % released = Time Abs. ( total vol / vol x 900 /1000 (conc./original (min) at 243 nm taken from the (mg/900ml) strength) x 100 sample) 5 10 15 20 25 30 Results of the dissolution of paracetamol tablets Unufficial Test (Methylcellulose): Dilution factor = Conc. =[(abs-a)/b]x dil factor % released = Time Abs. ( total vol / vol x 900 /1000 (conc./original (min) at 243 nm taken from the (mg/900ml) strength) x 100 sample) 5 10 15 20 25 30 Results of the dissolution of paracetamol tablets Unofficial Test (Simple syrup): Dilution factor = Conc. =[(abs-a)/b]x dil factor % released = Time Abs. ( total vol / vol x 900 /1000 (conc./original (min) at 243 nm taken from the (mg/900ml) strength) x 100 sample) 5 10 15 20 25 30 Plot the Time versus % release on graph paper and comment on the effect of the Viscosity on the drug released rate?? Determine the t80% of the drug?? Comment on the release of the drug from the products at 30 minute according to USP requirements (For phosphate buffer pH 5.8 in water)
Results of the dissolution of paracetamol tablets Official Test: Time (min) Abs. at 243 nm Dilution factor = ( total vol / vol taken from the sample) Conc. =[(abs-a)/b]x dil factor x 900 /1000 (mg/900ml) % released = (conc./original strength) x 100 5 10 15 20 25 30 Results of the dissolution of paracetamol tablets Unufficial Test (Methylcellulose): Time (min) Abs. at 243 nm Dilution factor = ( total vol / vol taken from the sample) Conc. =[(abs-a)/b]x dil factor x 900 /1000 (mg/900ml) % released = (conc./original strength) x 100 5 10 15 20 25 30 Results of the dissolution of paracetamol tablets Unofficial Test (Simple syrup): Time (min) Abs. at 243 nm Dilution factor = ( total vol / vol taken from the sample) Conc. =[(abs-a)/b]x dil factor x 900 /1000 (mg/900ml) % released = (conc./original strength) x 100 5 10 15 20 25 30 Plot the Time versus % release on graph paper and comment on the effect of the Viscosity on the drug released rate?? Determine the t80% of the drug?? Comment on the release of the drug from the products at 30 minute according to USP requirements (For phosphate buffer pH 5.8 in water)
pht_414.docx