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What are needed to demonstrate completely success vaccines? of DC delivery Why are immunization protocols important? Protocols are important adjunct to traditional therapies What is the first step of traditional tumor therapy? Tumors will first be de-bulked In tumor therapy what will eradicate immune system after tumors will be Residual tumor and micro metastases What is the reason of active and increased optimism in recent years? The increased understanding of tumor immunology The specific immune response to bacterial infections includes formation of what? antibodies Antibodies in a response to bacterial infection are produced to what? to exotoxins or other secreted bacterial products Antibody formation is the main defense against what bacteria? extracellular bacteria What is helpful in attacking intracellular bacteria? cell-mediated immunity Why Bacteria have developed several ways? to inhibit the immune response Why Bacteria have developed several ways? make it more difficult for the immune response to occur What is one of the mechanism of bacterial development to inhibit immune response? avoiding antibody What is one of the mechanism of bacterial development to inhibit immune response? blocking phagocytosis What is one of the mechanism of bacterial development to inhibit immune response? inactivating the complement cascade How does the mechanism of avoiding the effects of antibody occur? through altering bacterial antigens (epitopes) The mechanism of avoiding the effects of antibody through altering bacterial antigens (epitopes) as a result of what? genetic mutations How some bacteria can avoid effect of antibodies? By down-regulation of MHC molecules How some bacteria can effect of antibodies? produce proteases that degrade IgA What is a target of most of the evasion mechanisms of bacteria? the process of phagocytosis What are the stages of bacterial defense in the process of phagocytosis? chemotaxis, adhesion, and digestion
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