(Tollefson et al. Fluoxetine 20 Yes 6 T6 335 53.7 67.7±5.7 No 61 - Yes 1995)() Placebo 336 55.4 67.7±5.7 42 - et al. Duloxetine 83.5 Yes 12 T12 27 40.7 63.6 ±10.9 No 1 - Yes 2011)() (Tourian et al. Duloxetine 60 No 8 T8 157 66 39±12 No 29 23 Yes 2009)() Desvenlafaxine 50 148 69 41±13) 16 9 Desvenlafaxine 100 150 66 39±12 21 17 Placebo 160 58 39±13 5 4 (Tzanakaki et Fluoxetine 20-60 Yes 6 T6 54 83.3 49±10 No 1 - Yes al. 2000)() Venlafaxine 75-225 55 74.5 47±11 7 - (Tzeng et al. Mirtazapine 33.2 No 7 T7 58 55.2 47.7 ±16.6 SUD - 4 No 2009)() (Urbina et al. Fluoxetine 20 Yes 6 T6 20 95 34.4± 1.8 No 5 - No 1999)() (Vanderkooy et Bupropion 143.3±25.8 No 8 T8 15 73.3 41.1± 8.8 No 5 3 No al. 2002)() Sertraline 105.4±217.5 37 81.1 39.5± 11.4 5 12 81.4±58.4 Venlafaxine 62 61.3 40.8± 11.2 16 17 18.7±6.1 Paroxetine 55 38.2 38.1± 11.3 7 16 (Ventura et al. Escitalopram 10 Yes 8 T8 104 54.8 40.6± 13.7 No 14 12 Yes 2007)() Sertraline 113.6 107 59.8 38.1± 11.5 18 6 (Versiani et al. Fluoxetine 20 No 8 T8 77 - - No 3 11 No 1999)() (Versiani et al. Reboxetine 10 Yes 6 T6 28 46.4 41.7 No 7 - Yes 2000)()
(Tollefson et al. 1995)() Fluoxetine Placebo 20 Yes 6 T6 335 336 53.7 55.4 67.7±5.7 67.7±5.7 No 61 42 - - Yes et al. 2011)() Duloxetine 83.5 Yes 12 T12 27 40.7 63.6 ±10.9 No 1 - Yes (Tourian et al. 2009)() Duloxetine Desvenlafaxine Desvenlafaxine Placebo 60 50 100 No 8 T8 157 148 150 160 66 69 66 58 39±12 41±13) 39±12 39±13 No 29 16 21 5 23 9 17 4 Yes (Tzanakaki et al. 2000)() Fluoxetine Venlafaxine 20-60 75-225 Yes 6 T6 54 55 83.3 74.5 49±10 47±11 No 1 7 - - Yes (Tzeng et al. 2009)() Mirtazapine 33.2 No 7 T7 58 55.2 47.7 ±16.6 SUD - 4 No (Urbina et al. 1999)() Fluoxetine 20 Yes 6 T6 20 95 34.4± 1.8 No 5 - No (Vanderkooy et al. 2002)() Bupropion Sertraline Venlafaxine Paroxetine 143.3±25.8 105.4±217.5 81.4±58.4 18.7±6.1 No 8 T8 15 37 62 55 73.3 81.1 61.3 38.2 41.1± 8.8 39.5± 11.4 40.8± 11.2 38.1± 11.3 No 5 5 16 7 3 12 17 16 No (Ventura et al. 2007)() Escitalopram Sertraline 10 113.6 Yes 8 T8 104 107 54.8 59.8 40.6± 13.7 38.1± 11.5 No 14 18 12 6 Yes (Versiani et al. 1999)() Fluoxetine 20 No 8 T8 77 - - No 3 11 No (Versiani et al. 2000)() Reboxetine 10 Yes 6 T6 28 46.4 41.7 No 7 - Yes
JCP_00_00_2015_03_31_SERRETTI_JCP14173_SDC1.docx