result is non-motile” MRSA has the appearance of a of (Alexander, 2010). ‘bunch grapes’ under the microscope due to of the 2012). the, “activity coagulase enzyme” ("bioquell.com", Habitat The natural habitat of S. epidermidis is, and warm, typically on catheters, surgical “protein-rich wound, synthetic knees, hips or plates, and pins at fracture sites ("eHow," 2013) which are common in the hospital setting. S. aureus thrives in the hospital setting and are extremely virulent, resistant to most antibiotics and in use ("eHow," 2013). Staph is disinfectants” currently also known to common sites of colonization include the nostrils, thrive in, “warm, moist places; belly button, underarms, and 2012) which are common in over populated groin” (“cdc.gov,” areas within the community. Genetic Mechanism Resistance of MRSA has been identified as resistance to methicillin [which] having, “High-level is caused by the mecA gene, the presence of the mec gene is an absolute requirement for S. aureus to express methicillin resistance (Lowy, 2013) which [then] encodes an alternative penicillin-binding protein, PBP 2a” (Wielders, Fluit, Brisse, Verhoef, & Schmitz). “HA-MRSA and CA-MRSA differ at the genetic level and have distinct biologic properties. These differences suggest that CA-MRSA strains may spread more easily from person to person or cause more skin disease than HA-MRSA. At least three different strains of staph that causes CA-MRSA” (Baylor College of Medicine, 2013). The mecA gene is part of a 21- to 60-kb Staphylococcal Chromosome Cassette mec (SCCmec), a mobile genetic element that may also contain genetic structures such as Tn554, pUB110, and pT181 which encode resistance to non-β-lactam et mecA has been detected in antibiotics” (Wielders al.). “By using DNA microarray technology,
result is non-motile” (Alexander, 2010). MRSA has the appearance of a ‘bunch of grapes’ under the microscope due to the, “activity of the coagulase enzyme” ("bioquell.com", 2012). Habitat The natural habitat of S. epidermidis is, “protein-rich and warm, typically on catheters, surgical wound, synthetic knees, hips or plates, and pins at fracture sites ("eHow," 2013) which are common in the hospital setting. S. aureus thrives in the hospital setting and are extremely virulent, resistant to most antibiotics and disinfectants” currently in use ("eHow," 2013). Staph is also known to thrive in, “warm, moist places; common sites of colonization include the nostrils, belly button, underarms, and groin” (“cdc.gov,” 2012) which are common in over populated areas within the community. Genetic Mechanism Resistance of MRSA has been identified as having, “High-level resistance to methicillin [which] is caused by the mecA gene, the presence of the mec gene is an absolute requirement for S. aureus to express methicillin resistance (Lowy, 2013) which [then] encodes an alternative penicillin-binding protein, PBP 2a” (Wielders, Fluit, Brisse, Verhoef, & Schmitz). “HA-MRSA and CA-MRSA differ at the genetic level and have distinct biologic properties. These differences suggest that CA-MRSA strains may spread more easily from person to person or cause more skin disease than HA-MRSA. At least three different strains of staph that causes CA-MRSA” (Baylor College of Medicine, 2013). The mecA gene is part of a 21- to 60-kb Staphylococcal Chromosome Cassette mec (SCCmec), a mobile genetic element that may also contain genetic structures such as Tn554, pUB110, and pT181 which encode resistance to non-β-lactam antibiotics” (Wielders et al.). “By using DNA microarray technology, mecA has been detected in
HospitalandcommunityaquiredMRSA.docx