C9 DNP No data No data C6-10 Di-C6-10 Rat: Rat: PE 450 (F0): seminal vesicle weight 450: litter survival, pup weight ↓ ↓ ↓ Rat: C9-11 Di-C9-11 NE 500: skeletal variations (lumbar ↑ PE ribs) C9, C10 DIDP NE Two generation study: Rat: 134-352 (0.2%): pup survival in F2 ↓ Developmental study: Rat: 1000: skeletal variations (cervical and lumbar ribs) ↑ C10 DIUP No data No data C11 DUP No data No data C12-rich DITDP No data No data C13 DTDP NE NE LOAEL derived from exposure to adult male. F1 i.e. including prenatal exposure included for comparison. 1 f female; m male; NE not established – – –
C9 DNP No data No data C6-10 Di-C6-10 PE Rat: 450 (F0): ↓ seminal vesicle weight Rat: 450: ↓ litter survival, ↓ pup weight C9-11 Di-C9-11 PE NE Rat: 500: ↑ skeletal variations (lumbar ribs) C9, C10 DIDP NE Two generation study: Rat: 134-352 (0.2%): ↓ pup survival in F2 Developmental study: Rat: 1000: ↑ skeletal variations (cervical and lumbar ribs) C10 DIUP No data No data C11 DUP No data No data C12-rich DITDP No data No data C13 DTDP NE NE 1 LOAEL derived from exposure to adult male. F1 i.e. including prenatal exposure included for comparison. f – female; m – male; NE – not established
Phthalates-hazard-compendium.docx