Mask 1 Mask 2 Outcome Measure T 1 T 2 T 3 T 1 T2 T3 Interface Pressure Nose 84 132 94 102 121 158 ±54 (mmHg) mean ± sted.dev. ±39 ±63 ±49 ±52 ±55 Interface Pressure Right 32 42 39 41 36 cheek (mmHg) mean ± 54 ±24 ±18 ±21 ±12 ±21 ±20 sted.dev. Interface Pressure Left 37 30 32 38 33 cheek (mmHg) mean ± 42 ±24 ±17 ±13 ±21 ±26 ±29 sted.dev. 34 33 34 34 Temperature (deg C) 34 34 (32-36) median and range (32-35) 84 84 80 84 Humidity (% RH) median 83 84 (77-92) and (67-91) Discomfort 5 4 5 5 4 6 (0-7) (VAS /10)* median and (0-7) range * 1= very comfortable, 10 = very uncomfortable. 3.3 Cytokine Analysis It was evident that for IL-1α, there was a general increase in cytokine ratio at the highest strap tension (T3) for both masks. Indeed, this increase in ratio was significant for M2 (p<0.05), with a median ratio of 1.34 in IL-1α concentrations at T3 (Figure 2), representing increases for 10/13 (79%) of the participants. There was only modest increases in IL-1α ratio (median ratios of 0.97-1.18) between strap tension (T2) and the optimal fitting (T1), with differences not being statistically significant (p>0.05).
Outcome Measure Mask 1 Mask 2 T 1 T 2 T 3 T 1 T2 T3 Interface Pressure Nose (mmHg) mean ± sted.dev. 84 ±39 132 ±63 158 ±54 94 ±49 102 ±52 121 ±55 Interface Pressure Right cheek (mmHg) mean ± sted.dev. 32 ±18 42 ±21 54 ±24 39 ±12 41 ±21 36 ±20 Interface Pressure Left cheek (mmHg) mean ± sted.dev. 37 ±17 30 ±13 42 ±24 32 ±21 38 ±26 33 ±29 Temperature (deg C) median and range 34 (32-35) 34 34 (32-36) 33 34 34 Humidity (% RH) median and 83 (67-91) 84 84 (77-92) 84 80 84 Discomfort (VAS /10)* median and range 4 (0-7) 5 6 (0-7) 4 5 5 * 1= very comfortable, 10 = very uncomfortable. 3.3 Cytokine Analysis It was evident that for IL-1α, there was a general increase in cytokine ratio at the highest strap tension (T3) for both masks. Indeed, this increase in ratio was significant for M2 (p<0.05), with a median ratio of 1.34 in IL-1α concentrations at T3 (Figure 2), representing increases for 10/13 (79%) of the participants. There was only modest increases in IL-1α ratio (median ratios of 0.97-1.18) between strap tension (T2) and the optimal fitting (T1), with differences not being statistically significant (p>0.05).
Investigating%2520the%2520Effects%2520of%2520Strap%2520tension%2520during%2520Non-Invasive.docx