SLR I 24 cohort, To assess the effects of use of who used cannabis during pregnancy Aim: () cannabis during pregnancy on maternal had an increase in the odds of anaemia and outcomes. (pooled OR (pOR) 1.36: 95%CI 1.10 to 1.69) and compared with women who did not. Infants Methods: Seven electronic databases exposed to cannabis in utero had a decrease were searched from inception to 1 April studies in birth weight (low birth weight pOR 1.77: 95% 2014. Case-control studies, cross-sectional CI 1.04 to 3.01; pooled mean difference and cohort studies that investigated the (pMD) for birth weight 109.42 g: 38.72 to effects of use of cannabis during 180.12) compared with infants were not. pregnancy on maternal and fetal Infants exposed to cannabis in utero were outcomes were included. Data synthesis also more likely to need placement in the was undertaken via systematic review and neonatal intensive care unit compared with meta-analysis of available evidence. infants whose mothers did not use cannabis Meta-analyses were conducted on during pregnancy (pOR=2.02: 1.27 to 3.21). variables that had three or more studies that measured an outcome in a consistent As use of cannabis gains social acceptance, manner, these included: anaemia, birth pregnant women and their providers weight, low birth weight, neonatal length, could benefit from health education on placement in the neonatal intensive care potential adverse effects of use of cannabis unit, gestational age, head circumference during pregnancy. and preterm birth. 1.5 Excluded studies Background papers Background information will inform revision of the narrative.
() SLR I 24 cohort, and studies Aim: To assess the effects of use of cannabis during pregnancy on maternal and outcomes. Methods: Seven electronic databases were searched from inception to 1 April 2014. Case-control studies, cross-sectional and cohort studies that investigated the effects of use of cannabis during pregnancy on maternal and fetal outcomes were included. Data synthesis was undertaken via systematic review and meta-analysis of available evidence. Meta-analyses were conducted on variables that had three or more studies that measured an outcome in a consistent manner, these included: anaemia, birth weight, low birth weight, neonatal length, placement in the neonatal intensive care unit, gestational age, head circumference and preterm birth. who used cannabis during pregnancy had an increase in the odds of anaemia (pooled OR (pOR) 1.36: 95%CI 1.10 to 1.69) compared with women who did not. Infants exposed to cannabis in utero had a decrease in birth weight (low birth weight pOR 1.77: 95% CI 1.04 to 3.01; pooled mean difference (pMD) for birth weight 109.42 g: 38.72 to 180.12) compared with infants were not. Infants exposed to cannabis in utero were also more likely to need placement in the neonatal intensive care unit compared with infants whose mothers did not use cannabis during pregnancy (pOR=2.02: 1.27 to 3.21). As use of cannabis gains social acceptance, pregnant women and their providers could benefit from health education on potential adverse effects of use of cannabis during pregnancy. 1.5 Excluded studies Background papers Background information will inform revision of the narrative.
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