Chronic mucosal STAT1-GOF, Defective Th17, candidiasis deficiency, AIRE-deficiency autoantiobodies against (APECED), IL17F/IL-17RA ACT1 deficiency, IL17RC deficiency, DOCK8 deficiency Aspergillosis CGD, Defective ROS production, GATA2 deficiency defective Th17/neutrophil recruitment, defective haematopoiesis Deep dermatophytosis CARD9-deficiency, defective Th17/neutrophil recruitment Cryptococcosis Autoantibodies against Neutralization of GM-CSF/IFNγ or IFNγ, primary CD4 bioactivity, defective Th lymphopenia, function, defective deficiency haematopoiesis Dimorphic fungi Interleukin-12Rb1 Defective Th1 function, deficiency, IFNγR deficiency, defective Th17 function, STAT1-GOF, GATA2 defective haematopoiesis deficiency Pneumocystosis SCID, X-linked CD40 ligand Defective CD4 lymphocyte deficiency, CARD11 function, defective NFkB deficiency, MHC class II modulation deficiency, NEMO deficiency Abbreviations: dimorphic fungi (histoplasmosis, coccidioidomycosis, paracoccidioidomycosis), APECED (autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy), CGD (chronic granulomatous disease), Th (T-helper lymphocyte)
Chronic mucosal candidiasis STAT1-GOF, AIRE-deficiency (APECED), IL17F/IL-17RA deficiency, ACT1 deficiency, IL17RC deficiency, DOCK8 deficiency Defective Th17, autoantiobodies against Aspergillosis CGD, GATA2 deficiency Defective ROS production, defective Th17/neutrophil recruitment, defective haematopoiesis Deep dermatophytosis CARD9-deficiency, defective Th17/neutrophil recruitment Cryptococcosis Autoantibodies against or IFNγ, primary CD4 lymphopenia, deficiency Neutralization of GM-CSF/IFNγ bioactivity, defective Th function, defective haematopoiesis Dimorphic fungi Interleukin-12Rb1 deficiency, IFNγR deficiency, STAT1-GOF, GATA2 deficiency Defective Th1 function, defective Th17 function, defective haematopoiesis Pneumocystosis SCID, X-linked CD40 ligand deficiency, CARD11 deficiency, MHC class II deficiency, NEMO deficiency Defective CD4 lymphocyte function, defective NFkB modulation Abbreviations: dimorphic fungi (histoplasmosis, coccidioidomycosis, paracoccidioidomycosis), APECED (autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy), CGD (chronic granulomatous disease), Th (T-helper lymphocyte)
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