measures. In a third study comparing laser versus resection therapy, only one outcome (maximum flow) presented significant differences in favour of resection. Also EQ5D reported greater gains for resection than laser therapy (p value N/A). In a fourth study, while the number of leaks avoided did not show any significant reduction for the three comparisons between active treatment arms, EQ5D showed statistically significant gains for 2 of three comparisons (p<0.05) Devine Chronic Low Poor EQ5D Effect size The pooled mean effect size for the EQ5D Back Pain was 0.78 +- 0.12. Haywood Older Poor EQ5D 1 Difference One study reported that EQ5D had the population between ability to discriminate over treatment treatment arms groups (p N/R) Hill Spinal Cord Poor SF6D 1 Difference In one study it was reported that SF6D Injury between could discriminate between the two groups treatment arms (p values N/R). Janssen Diabetes type 2 Good EQ5D 4 Change over In one study a significant decline in health time over a 2 years period was found for the EQ5D index (f=5.97, p=0.003) and the
measures. In a third study comparing laser versus resection therapy, only one outcome (maximum flow) presented significant differences in favour of resection. Also EQ5D reported greater gains for resection than laser therapy (p value N/A). In a fourth study, while the number of leaks avoided did not show any significant reduction for the three comparisons between active treatment arms, EQ5D showed statistically significant gains for 2 of three comparisons (p<0.05) Devine Chronic Low Back Pain Poor EQ5D Effect size The pooled mean effect size for the EQ5D was 0.78 +- 0.12. Haywood Older population Poor EQ5D 1 Difference between treatment arms One study reported that EQ5D had the ability to discriminate over treatment groups (p N/R) Hill Spinal Cord Injury Poor SF6D 1 Difference between treatment arms In one study it was reported that SF6D could discriminate between the two groups (p values N/R). Janssen Diabetes type 2 Good EQ5D 4 Change over time In one study a significant decline in health over a 2 years period was found for the EQ5D index (f=5.97, p=0.003) and the
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