Single copies of chains A and B are seen in the molecular images in the above steps. In its storage form insulin has been shown to form hexameric assemblies. Select the Biological Assembly 3 from the Structure menu in the section to show this hexameric structure of insulin. It pull-down Structure Details should appear like the following: Examine the structure closely. What are the purple and green dots in the center of the structure? Q8. The title of the structure suggests that there is zinc in the structure. Where is it located? Q9. What is the function of the zinc ion(s)? Q10. e. Using the other visualization tools At the bottom of the JSmol graphics window select other viewers to see the same structure (PDB ID 1trz). The insulin molecule as visualized by and are shown below: PV NGL View in PV View in NGL Both the visualization software shown above have their own advantages. For example, PV allows viewing the molecule based on symmetry, while NGL displays superior speed even when displaying very large molecules. Complete the following questions for HW:
Single copies of chains A and B are seen in the molecular images in the above steps. In its storage form insulin has been shown to form hexameric assemblies. Select the Biological Assembly 3 from the Structure pull-down menu in the Structure Details section to show this hexameric structure of insulin. It should appear like the following: Examine the structure closely. Q8. What are the purple and green dots in the center of the structure? Q9. The title of the structure suggests that there is zinc in the structure. Where is it located? Q10. What is the function of the zinc ion(s)? e. Using the other visualization tools At the bottom of the JSmol graphics window select other viewers to see the same structure (PDB ID 1trz). The insulin molecule as visualized by PV and NGL are shown below: View in PV View in NGL Both the visualization software shown above have their own advantages. For example, PV allows viewing the molecule based on symmetry, while NGL displays superior speed even when displaying very large molecules. Complete the following questions for HW:
Insulin-tutorial.docx