Section(s) involved Amendment The title of SMI document ID 3 referred to in the Scope of document. text has been updated. Taxonomy updated. More information has been added to the Characteristics section. Removal of two sentences Introduction. on PCR from this section. Section on Principles of Identification has been updated to reflect the four preliminary tests used in identification of Corynebacterium species. Updated to include information regarding use of Technical sheep blood agar media and variability of the Information/Limitations. nitrate test. This section has been updated to include the Safety considerations. laboratory - acquired infections as well as guidelines laid out by the DH Green book. Updates have been done on 3.3, 3.4 and 3.6 to reflect standards in practice. The table has also been updated with references and two more columns to include the catalase and pyrazinamidase tests. The footnote in the table has also been updated. TP 36 Urease Test has been hyperlinked. Variable test results for nitrate test in C. Identification. pseudotuberculosis have also been mentioned. Referral of isolate to the Reference Laboratory has been updated. References used for the table are listed in the footnote. Subsection 3.5 has been updated to include the Rapid Molecular Methods. Addition of flowchart for identification of Identification Flowchart. Corynebacterium species has been developed for guidance. Subsections 5.1, 5.2, 5.4, 5.5 and 5.6 have been updated to reflect reporting practice. Reporting. The webpage link in section 5.4 and 5.5 has been removed as it is not accessible. Referral. The address of the Reference Laboratory has
Section(s) involved Amendment Scope of document. The title of SMI document ID 3 referred to in the text has been updated. Introduction. Taxonomy updated. More information has been added to the Characteristics section. Removal of two sentences on PCR from this section. Section on Principles of Identification has been updated to reflect the four preliminary tests used in identification of Corynebacterium species. Technical Information/Limitations. Updated to include information regarding use of sheep blood agar media and variability of the nitrate test. Safety considerations. This section has been updated to include the laboratory - acquired infections as well as guidelines laid out by the DH Green book. Identification. Updates have been done on 3.3, 3.4 and 3.6 to reflect standards in practice. The table has also been updated with references and two more columns to include the catalase and pyrazinamidase tests. The footnote in the table has also been updated. TP 36 Urease Test has been hyperlinked. Variable test results for nitrate test in C. pseudotuberculosis have also been mentioned. Referral of isolate to the Reference Laboratory has been updated. References used for the table are listed in the footnote. Subsection 3.5 has been updated to include the Rapid Molecular Methods. Identification Flowchart. Addition of flowchart for identification of Corynebacterium species has been developed for guidance. Reporting. Subsections 5.1, 5.2, 5.4, 5.5 and 5.6 have been updated to reflect reporting practice. The webpage link in section 5.4 and 5.5 has been removed as it is not accessible. Referral. The address of the Reference Laboratory has
ID_2i4.1.docx