Table 1: The Role of Interleukins 1to10 (IL-1 to IL-10) in Healing INTERLEUKIN ROLE SOURCE IL-1 Induces fever, ACTH release, Macrophages, mast cells, keratinocytes, enhances TNF-, IFN-; activates lymphocytes. granulocytes, endothelial cells, stimulates haematopoiesis. IL-2 Activates macrophages, T Macrophages, mast cells, lymphocytes, NK cells, stimulates keratinocytes, differentiation of B lymphocyte; T lymphocytes. induces fever. IL-3 Stimulates bone marrow stem cells T lymphocyte IL-4 Early: Stimulates fibroblast Mast cells. proliferation; Late: Downregulates cytokine expression IL-5 B-cell differentiation, eosinophil TH2 lymphocytes and IgA production
Table 1: The Role of Interleukins 1to10 (IL-1 to IL-10) in Healing INTERLEUKIN ROLE SOURCE IL-1 Induces fever, ACTH release, enhances TNF-, IFN-; activates granulocytes, endothelial cells, stimulates haematopoiesis. Macrophages, mast cells, keratinocytes, lymphocytes. IL-2 Activates macrophages, T lymphocytes, NK cells, stimulates differentiation of B lymphocyte; induces fever. Macrophages, mast cells, keratinocytes, T lymphocytes. IL-3 Stimulates bone marrow stem cells T lymphocyte IL-4 Early: Stimulates fibroblast proliferation; Late: Downregulates cytokine expression Mast cells. IL-5 B-cell differentiation, eosinophil and IgA production TH2 lymphocytes
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