Table 3 Continued Reference Objective Population Study Design Disease Incidence Reinfection Limitations or Prevalence Results Niccolai et. Determine Sexually active Prospective cohort. Not provided 17.5% Unsure of infection al [21] relationship women; 14-19 Interviews and ct/gc origins; recall bias; between years old; 50% screening. small sample size. knowing your pregnant; partner has been history of STI treated for past STI and current infection Ellen et al. Examine risk for Men 13-25 Prospective cohort. N/A 6.5% Small sample size; [22] repeat infections from screening Interviews and ct/gc limited power; low with reducing project; screening acceptance rate; number of Asymptomatic; short follow-up sexual partners 2 U.S cities among men Magnus et al. Determine if Females Subanalysis of N/A 16.1% Selection bias; short [23] older sexual parent RCT follow-up; recall partners Infected with bias; not associated with ct generalizable; recurrent unable to link chlamydia 19.9% of partners among adolescent women Champion et Evaluate rate of 14-45 year old Subanalysis of Not provided 59.4% abused Recall bias; limited al [24] reinfection parent RCT 43.3% power in some risk stratified by unabused categories history of abuse women Niccolai et. Determine 14-19 year old Prospective cohort. Prevalence = 56.9% Did not confirm al [25] frequency and females; 10 Interviews, medical 52.6% STI history; did not patterns of public health record review, ct confirm treatment; chlamydia clinics screening, review of do not know if among health department screened between adolescent reports. follow-ups women
Table 3 Continued Reference Objective Population Study Design Disease Incidence or Prevalence Reinfection Results Limitations Niccolai et. al [21] Determine relationship between knowing your partner has been treated for past STI and current infection Sexually active women; 14-19 years old; 50% pregnant; history of STI Prospective cohort. Interviews and ct/gc screening. Not provided 17.5% Unsure of infection origins; recall bias; small sample size. Ellen et al. [22] Examine risk for repeat infections with reducing number of sexual partners among men Men 13-25 from screening project; Asymptomatic; 2 U.S cities Prospective cohort. Interviews and ct/gc screening N/A 6.5% Small sample size; limited power; low acceptance rate; short follow-up Magnus et al. [23] Determine if older sexual partners associated with recurrent chlamydia among adolescent women Females Infected with ct Subanalysis of parent RCT N/A 16.1% Selection bias; short follow-up; recall bias; not generalizable; unable to link 19.9% of partners Champion et al [24] Evaluate rate of reinfection stratified by history of abuse 14-45 year old women Subanalysis of parent RCT Not provided 59.4% abused 43.3% unabused Recall bias; limited power in some risk categories Niccolai et. al [25] Determine frequency and patterns of chlamydia among adolescent women 14-19 year old females; 10 public health clinics Prospective cohort. Interviews, medical record review, ct screening, review of health department reports. Prevalence = 52.6% 56.9% Did not confirm STI history; did not confirm treatment; do not know if screened between follow-ups
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