What is the cause of death in Infectious crises most frequent patients younger than 5 years? In what age does vasoocclusive disease develops? Between the ages of 12 months and 6 years. In pregnancy, there is no increase in disease Maternal mortality of 20% manifestation but there is an increase in the Fetal mortality of 20% following: The two main causes of erythropoietic Aplastic crises suppression are the following: Megaloblastic erythropoiesis Aplastic crises result from which virus infection? Parvovirus What is a significant cause of death in patients of Acute chest syndrome all ages who have sickle cell anemia? What percentage of patients with sickle cell 50% anemia survive beyond the fifth decade? What are the general signs and symptoms of Pain sickle cell anemia? Pulmonary complications Stroke What can be seen on peripheral smears if patient Sickled red cells (drepanocytes) is in acute crisis state? What are the laboratory features? Reticulocytosis (8% to 12%) An increased mean corpuscular volume (MCV) to levels up to 100 fL Elevated serum; unconjugated bilirubin and methemalbumin Decreased serum haptoglobin and hemopexin Increased serum lactate dehydrogenase (LDH) Mildly increased aspartate transaminase (AST) Increased urine urobilinogen
What is the most frequent cause of death in patients younger than 5 years? Infectious crises In what age does vasoocclusive disease develops? Between the ages of 12 months and 6 years. In pregnancy, there is no increase in disease manifestation but there is an increase in the following: Maternal mortality of 20% Fetal mortality of 20% The two main causes of erythropoietic suppression are the following: Aplastic crises Megaloblastic erythropoiesis Aplastic crises result from which virus infection? Parvovirus What is a significant cause of death in patients of all ages who have sickle cell anemia? Acute chest syndrome What percentage of patients with sickle cell anemia survive beyond the fifth decade? 50% What are the general signs and symptoms of sickle cell anemia? Pain Pulmonary complications Stroke What can be seen on peripheral smears if patient is in acute crisis state? Sickled red cells (drepanocytes) What are the laboratory features? Reticulocytosis (8% to 12%) An increased mean corpuscular volume (MCV) to levels up to 100 fL Elevated serum; unconjugated bilirubin and methemalbumin Decreased serum haptoglobin and hemopexin Increased serum lactate dehydrogenase (LDH) Mildly increased aspartate transaminase (AST) Increased urine urobilinogen
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