(Cohn et al. Fluoxetine 20-80 No 6 T6 54 72.2 41 No 11 20 No 1985)() Placebo 58 63.6 44 4 9 (Cohn et al. Paroxetine 30.9 Yes 6 T6 40 60 42.3 No 8 9 No 1992)() Placebo 40 42.5 41.3 5 7 (Coleman et al. Bupropion 290 Yes 8 T8 119 56 38.1 No 24 - Yes 1999)() Sertraline 106 115 54 38.3 20 - Placebo 121 59 38.5 8 - (Coleman et al. Bupropion 319 No 8 T8 150 63 36.6 No 21 4 Yes 2001)() Fluoxetine 26 154 66 37.1 15 17 Placebo 152 61 36.7 10 6 (Cooper-Kazaz Sertraline + 85.5 ± 15.7 Yes 8 T8 50 58 41.0± 55.8 No 31 34 No et al. 2007)() Placebo (Corrigan et al. Fluoxetine 20 No 8 T8 33 - 42 No 6 3 No 2000)() Placebo 34 - 42 1 2 (Costa e Silva Fluoxetine 20-40 Yes 8 T8 185 77.8 39.8± 10.3 No 15 3 No 1998)() Venlafaxine 75-150 194 80.9 40.5± 10.7 12 16 (Cunha et al. Venlafaxine 75 No 6 T6 14 85.7 77.6 ±7.3 Mild or 0 1 No 2007)() moderate Placebo 17 64.7 77.6 ±5.8 2 1 dementia (Cunningham et Venlafaxine 156-160 Yes 6 T6 72 - 40.7 No - 31 Yes al. 1994)() Placebo 76 - 40.7 - 9 (Cunningham et Venlafaxine XR 115-125 Yes 12 T12 97 63.0 39.7± 11.0 No - 20 Yes al. 1997)() Venlafaxine IR 124-140 96 66.6 42.8± 11.4 - 23
(Cohn et al. 1985)() Fluoxetine Placebo 20-80 No 6 T6 54 58 72.2 63.6 41 44 No 11 4 20 9 No (Cohn et al. 1992)() Paroxetine Placebo 30.9 Yes 6 T6 40 40 60 42.5 42.3 41.3 No 8 5 9 7 No (Coleman et al. 1999)() Bupropion Sertraline Placebo 290 106 Yes 8 T8 119 115 121 56 54 59 38.1 38.3 38.5 No 24 20 8 - - - Yes (Coleman et al. 2001)() Bupropion Fluoxetine Placebo 319 26 No 8 T8 150 154 152 63 66 61 36.6 37.1 36.7 No 21 15 10 4 17 6 Yes (Cooper-Kazaz et al. 2007)() Sertraline + Placebo 85.5 ± 15.7 Yes 8 T8 50 58 41.0± 55.8 No 31 34 No (Corrigan et al. 2000)() Fluoxetine Placebo 20 No 8 T8 33 34 - - 42 42 No 6 1 3 2 No (Costa e Silva 1998)() Fluoxetine Venlafaxine 20-40 75-150 Yes 8 T8 185 194 77.8 80.9 39.8± 10.3 40.5± 10.7 No 15 12 3 16 No (Cunha et al. 2007)() Venlafaxine Placebo 75 No 6 T6 14 17 85.7 64.7 77.6 ±7.3 77.6 ±5.8 Mild or moderate dementia 0 2 1 1 No (Cunningham et al. 1994)() Venlafaxine Placebo 156-160 Yes 6 T6 72 76 - - 40.7 40.7 No - - 31 9 Yes (Cunningham et al. 1997)() Venlafaxine XR Venlafaxine IR 115-125 124-140 Yes 12 T12 97 96 63.0 66.6 39.7± 11.0 42.8± 11.4 No - - 20 23 Yes
JCP_00_00_2015_03_31_SERRETTI_JCP14173_SDC1.docx