Escitalopram 20 123 68 39.6±12.0 14 - Placebo 119 60 40.1±10.6 3 - (Byerley et al. Fluoxetine 20-80 Yes 6 T6 32 75 38.9±10.7 No 4 - Yes 1988)() Placebo 29 61 37.5±9.1 2 - (Calabrese et al. Citalopram 24.6 No 6 T6 55 73 43 No 2 1 Yes 2003)() (Chouinard et Paroxetine 25.5 Yes 12 T12 102 40.6± 10.7 No No al. 1999)() Fluoxetine 27.5 101 41.2± 10.7 (Claghorn et al. Paroxetine 30 No 6 T6 168 50 40.6 Personality 25 34 Yes 1992)() disorders Placebo 179 54 42.8 8 14 (Claghorn et al. Mirtazapine 16.5 Yes 6 T6 42 52.4 39 No - 27 Yes 1995)() Placebo 40 45 40 - 2 (Claghorn et al. Fluvoxamine 92.7 ± 46.9 No 6 T6 50 64 39.0±10.9 No 3 19 No 1996)() Placebo 50 64 5 4 (Clayton et al. Bupropion 300-450 Yes 8 T8 276 58 37±12 No 39 8 Yes 2006)() Escitalopram 10-20 281 57 36±11 28 22 Placebo 273 60 36±11 21 14 (Clerc et al. Venlafaxine 200 No 6 T6 33 69.7 49.0 No 0 - Yes 1994)() Fluoxetine 40 34 67.6 53.6 1 - et al. Fluvoxamine 200 Yes 6 T6 56 82.1 51.2± 12.6 No 1 6 Yes 2001)() Milnacipran 100 57 75.4 48.7± 15.1 0 1
Escitalopram Placebo 20 123 119 68 60 39.6±12.0 40.1±10.6 14 3 - - (Byerley et al. 1988)() Fluoxetine Placebo 20-80 Yes 6 T6 32 29 75 61 38.9±10.7 37.5±9.1 No 4 2 - - Yes (Calabrese et al. 2003)() Citalopram 24.6 No 6 T6 55 73 43 No 2 1 Yes (Chouinard et al. 1999)() Paroxetine Fluoxetine 25.5 27.5 Yes 12 T12 102 101 40.6± 10.7 41.2± 10.7 No No (Claghorn et al. 1992)() Paroxetine Placebo 30 No 6 T6 168 179 50 54 40.6 42.8 Personality disorders 25 8 34 14 Yes (Claghorn et al. 1995)() Mirtazapine Placebo 16.5 Yes 6 T6 42 40 52.4 45 39 40 No - - 27 2 Yes (Claghorn et al. 1996)() Fluvoxamine Placebo 92.7 ± 46.9 No 6 T6 50 50 64 64 39.0±10.9 No 3 5 19 4 No (Clayton et al. 2006)() Bupropion Escitalopram Placebo 300-450 10-20 Yes 8 T8 276 281 273 58 57 60 37±12 36±11 36±11 No 39 28 21 8 22 14 Yes (Clerc et al. 1994)() Venlafaxine Fluoxetine 200 40 No 6 T6 33 34 69.7 67.6 49.0 53.6 No 0 1 - - Yes et al. 2001)() Fluvoxamine Milnacipran 200 100 Yes 6 T6 56 57 82.1 75.4 51.2± 12.6 48.7± 15.1 No 1 0 6 1 Yes
JCP_00_00_2015_03_31_SERRETTI_JCP14173_SDC1.docx