What is the visible aggregation of Agglutination particles caused by combination with specific antibody called? Antibodies that combine with particles Agglutinins are called? Antigens must be exposed and able to On the surface of the particle bind with the antibody because this reaction takes place where? What are the two steps in agglutination? Sensitization followed by lattice formation In order to form antibody bridges or Multiple antigenic/determiniant sites lattices, each particle must have? What are the different categories of Direct, passive, reverse passive, agglutination agglutination reactions? inhibition, and coagglutination In agglutination, what is the first reaction Sensitization step involving antigen-antibody combination through single antigenic determinants on the particle surface? The initial reaction in agglutination is Law of mass action rapid and reversible, it follows which law? The second step in agglutination is the Visible aggregates formation of cross-links that form? Sensitization can be affected by? the nature of the antibody molecule What determines how much an antibody Affinity and avidity remains attached? _____ with a potential valence of 10 is IgM, IgG over 700 times more efficient in agglutination that is ______ with a valence of 2. What is a key factor in the initial The nature of antigen-bearing surface sensitization process? What happens if epitopes are sparse or They are less likely to interact with an antibody obscured by other surface molecules? The second stage of agglutination is Environmental conditions, concentrations dependent on __________ and the relative _________of antigen and antibody. Lattice formation is governed by what Ionic strength, pH, and temperature factors? Antibodies must be able to bridge the One molecule being able to bind to two different gap between cells by? cells such as erythrocytes or bacterial They have a slight negative surface charge cells are difficult to bring together into lattice formation because?
What is the visible aggregation of particles caused by combination with specific antibody called? Agglutination Antibodies that combine with particles are called? Agglutinins Antigens must be exposed and able to bind with the antibody because this reaction takes place where? On the surface of the particle What are the two steps in agglutination? Sensitization followed by lattice formation In order to form antibody bridges or lattices, each particle must have? Multiple antigenic/determiniant sites What are the different categories of agglutination reactions? Direct, passive, reverse passive, agglutination inhibition, and coagglutination In agglutination, what is the first reaction involving antigen-antibody combination through single antigenic determinants on the particle surface? Sensitization step The initial reaction in agglutination is rapid and reversible, it follows which law? Law of mass action The second step in agglutination is the formation of cross-links that form? Visible aggregates Sensitization can be affected by? the nature of the antibody molecule What determines how much an antibody remains attached? Affinity and avidity _____ with a potential valence of 10 is over 700 times more efficient in agglutination that is ______ with a valence of 2. IgM, IgG What is a key factor in the initial sensitization process? The nature of antigen-bearing surface What happens if epitopes are sparse or obscured by other surface molecules? They are less likely to interact with an antibody The second stage of agglutination is dependent on __________ and the relative _________of antigen and antibody. Environmental conditions, concentrations Lattice formation is governed by what factors? Ionic strength, pH, and temperature Antibodies must be able to bridge the gap between cells by? One molecule being able to bind to two different cells such as erythrocytes or bacterial cells are difficult to bring together into lattice formation because? They have a slight negative surface charge
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