(Nierenberg et Duloxetine 60 Yes 8 T8 273 63.4 41.1±11.6 No 22 16 Yes al. 2007)() Escitalopram 10 274 67.9 43.3±13.0 21 18 Placebo 137 63.5 42.5±12.3 9 5 (Nonacs et al. Bupropion 262.5 Yes 8 T8 8 100 31.5 GAD,DAP, 2 - Yes 2005)() anxiety disorder NOS (Oliè et al. Escitalopram 12.1± 4.2 Yes 12 T12 790 70.5 44.5 ±12.5 Anxiety 30 12 Yes 2007)() disorders (Onder et al. Fluoxetine 20 No 12 T12 34 50 35.6± 7.7 No 7 - No 2003)() Fluoxetine 40 32 53.1 34.5± 8.6 17 - (Otsubo et al. Fluvoxamine 95.1 Yes 8 T8 36 50 45.3± 13.9 No - 12 No 2005)() (Ou et al. Citalopram 27.6 No 6 T6 117 53.8 36.4± 12.3 No 4 - No 2010)() Escitalopram 13.9 115 58.3 36.7± 12.5 3 - (Pae et al. Paroxetine 20-40 Yes 8 T8 52 59.6 43.0± 15.0 No 2 10 Yes 2004)() (Pae et al. Escitalopram 18.3 No 8 T8 17 70.6 43.9± 11.2 No 1 3 Yes 2008)() (Park et al. Escitalopram 9.0 ± 3.8 Yes 12 T12 79 100 49.1±7.6 No - 5 Yes 2012)() (Patris et al. Citalopram 20 Yes 8 T8 173 79.2 44 No 8 - Yes 1996)() Fluoxetine 20 184 75.5 43 10 - (Perahia et al. Duloxetine 80 Yes 8+26 T8 93 66.7 46.5 ±12.7 No 3 1 Yes 2006)() Duloxetine 120 103 74.8 44.0± 10.8 6 3
(Nierenberg et al. 2007)() Duloxetine Escitalopram Placebo 60 10 Yes 8 T8 273 274 137 63.4 67.9 63.5 41.1±11.6 43.3±13.0 42.5±12.3 No 22 21 9 16 18 5 Yes (Nonacs et al. 2005)() Bupropion 262.5 Yes 8 T8 8 100 31.5 GAD,DAP, anxiety disorder NOS 2 - Yes (Oliè et al. 2007)() Escitalopram 12.1± 4.2 Yes 12 T12 790 70.5 44.5 ±12.5 Anxiety disorders 30 12 Yes (Onder et al. 2003)() Fluoxetine Fluoxetine 20 40 No 12 T12 34 32 50 53.1 35.6± 7.7 34.5± 8.6 No 7 17 - - No (Otsubo et al. 2005)() Fluvoxamine 95.1 Yes 8 T8 36 50 45.3± 13.9 No - 12 No (Ou et al. 2010)() Citalopram Escitalopram 27.6 13.9 No 6 T6 117 115 53.8 58.3 36.4± 12.3 36.7± 12.5 No 4 3 - - No (Pae et al. 2004)() Paroxetine 20-40 Yes 8 T8 52 59.6 43.0± 15.0 No 2 10 Yes (Pae et al. 2008)() Escitalopram 18.3 No 8 T8 17 70.6 43.9± 11.2 No 1 3 Yes (Park et al. 2012)() Escitalopram 9.0 ± 3.8 Yes 12 T12 79 100 49.1±7.6 No - 5 Yes (Patris et al. 1996)() Citalopram Fluoxetine 20 20 Yes 8 T8 173 184 79.2 75.5 44 43 No 8 10 - - Yes (Perahia et al. 2006)() Duloxetine Duloxetine 80 120 Yes 8+26 T8 93 103 66.7 74.8 46.5 ±12.7 44.0± 10.8 No 3 6 1 3 Yes
JCP_00_00_2015_03_31_SERRETTI_JCP14173_SDC1.docx