Chemistry Specifications for Chemistry Services Contractors National Toxicology Program High Throughput Screen (HTS) Support Final August 11, 2016 1. Introduction Requirements related to chemicals designated for general high throughput screen evaluations have been discussed in previous sections of these specifications. Requirements discussed in this section apply to sets of chemicals, test articles, and/or mixtures (chemicals) that are currently sent for evaluation in the high throughput screen program known as Tox21 run by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health. Functional Activities in this section cover the procurement, handling and characterization of sets of chemicals for the Tox21 program. These activities are intended to apply to a set of chemicals, which constitute one complete plate used in the Tox21 program. Currently Tox21 plates consist of 1536 wells, containing 1408 individual chemicals or chemical mixtures. A typical set of chemicals addressed by the requirements in this section would therefore contain 1408 test articles (chemicals or chemical mixtures). 2. HTS Chemical Procurement (HCP)
Chemistry Specifications for Chemistry Services Contractors National Toxicology Program High Throughput Screen (HTS) Support Final August 11, 2016 1. Introduction Requirements related to chemicals designated for general high throughput screen evaluations have been discussed in previous sections of these specifications. Requirements discussed in this section apply to sets of chemicals, test articles, and/or mixtures (chemicals) that are currently sent for evaluation in the high throughput screen program known as Tox21 run by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health. Functional Activities in this section cover the procurement, handling and characterization of sets of chemicals for the Tox21 program. These activities are intended to apply to a set of chemicals, which constitute one complete plate used in the Tox21 program. Currently Tox21 plates consist of 1536 wells, containing 1408 individual chemicals or chemical mixtures. A typical set of chemicals addressed by the requirements in this section would therefore contain 1408 test articles (chemicals or chemical mixtures). 2. HTS Chemical Procurement (HCP)
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