Placebo 100 58.6 39.9± 10.1 - 9 (Currier et al. Bupropion 265± 65 No 6 T6 20 30 41.0 ±7.0 No 4 - Yes 2003)() (Currier et al. Citalopram 31.3± 11.1 No 6 T6 17 29.4 42.9± 8.4 Dysthymia 3 - Yes 2004)() (Dam et al. Fluoxetine + 20 No 6 T6 17 - - No 2 0 Yes 1998)() Placebo (Serretti et al. Fluvoxamine - Yes 6 T6 61 73.4 55.7 Personality 2 - No 2005)() disorders (De Montigny Venlafaxine 260 No 8 T8 158 72.2 42.9± 9.2 Dysthymia 74 - Yes et al. 1999)() et al. Fluoxetine 31.4 No 6 T6 18 61.1 35.4± 8.6 No 3 7 Yes 1988)() (DeMartinis et Desvenlafaxine 100 No 8 T8 118 65 40.4±12.1 No 26 24 Yes al. 2007)() Desvenlafaxine 200 116 61 40.7±12.8 21 25 Desvenlafaxine 400 116 54 39.0±12.6 35 30 Placebo 120 68 40.0±12.8 10 10 (Demir et al. Reboxetine 8-10 No 8 T8 24 83.3 - No 7 - No 2002)() (Detke et al. Duloxetine 60 Yes 9 T9 128 66 41±13 No 21 13 Yes 2002)() Placebo 139 71 41±15 19 9
Placebo 100 58.6 39.9± 10.1 - 9 (Currier et al. 2003)() Bupropion 265± 65 No 6 T6 20 30 41.0 ±7.0 No 4 - Yes (Currier et al. 2004)() Citalopram 31.3± 11.1 No 6 T6 17 29.4 42.9± 8.4 Dysthymia 3 - Yes (Dam et al. 1998)() Fluoxetine + Placebo 20 No 6 T6 17 - - No 2 0 Yes (Serretti et al. 2005)() Fluvoxamine - Yes 6 T6 61 73.4 55.7 Personality disorders 2 - No (De Montigny et al. 1999)() Venlafaxine 260 No 8 T8 158 72.2 42.9± 9.2 Dysthymia 74 - Yes et al. 1988)() Fluoxetine 31.4 No 6 T6 18 61.1 35.4± 8.6 No 3 7 Yes (DeMartinis et al. 2007)() Desvenlafaxine Desvenlafaxine Desvenlafaxine Placebo 100 200 400 No 8 T8 118 116 116 120 65 61 54 68 40.4±12.1 40.7±12.8 39.0±12.6 40.0±12.8 No 26 21 35 10 24 25 30 10 Yes (Demir et al. 2002)() Reboxetine 8-10 No 8 T8 24 83.3 - No 7 - No (Detke et al. 2002)() Duloxetine Placebo 60 Yes 9 T9 128 139 66 71 41±13 41±15 No 21 19 13 9 Yes
JCP_00_00_2015_03_31_SERRETTI_JCP14173_SDC1.docx