significant effect (RR 0.96 (95% CI 0.74 to 1.25) for any complication, RR 0.99 (95% CI 0.70 to 1.40) for wound complications). J et al, Systematic Smoking Smoking cessation 72 trials are included. 56 RCTs + Include 2009 Review Behaviour and interventions in pregnancy (over 20,000 pregnant women) Perinatal reduce the proportion of and 9 cluster-RCTs (over 5000 Interventions Outcomes women who continue to pregnant women) provided data in Pregnancy smoke in late pregnancy, and on smoking cessation outcomes. reduce low birthweight and Significant reduction in smoking Smoking preterm birth. Smoking in late pregnancy following Cessation cessation interventions in interventions (risk ratio (RR) pregnancy need to be 0.94, 95% confidence interval Prenatal, implemented in all maternity (CI) 0.93 to 0.96), an absolute maternal care settings. Given the difference of six in 100 women health and difficulty many pregnant who stopped smoking during early years women addicted to tobacco pregnancy. However, there is have quitting during significant heterogeneity in the pregnancy, population-based combined data (I2 > 60%). measures to reduce smoking In the trials with the lowest risk and social inequalities should of bias, the interventions had be supported less effect (RR 0.97, 95% CI 0.94 to 0.99), and lower heterogeneity (I2 = 36%). Eight trials of smoking relapse prevention (over 1000 women) showed no statistically significant reduction in relapse. Smoking cessation interventions reduced low birthweight (RR 0.83, 95% CI 0.73 to 0.95) and
significant effect (RR 0.96 (95% CI 0.74 to 1.25) for any complication, RR 0.99 (95% CI 0.70 to 1.40) for wound complications). J et al, 2009 Interventions in Pregnancy Smoking Cessation Prenatal, maternal health and early years Systematic Review Smoking Behaviour and Perinatal Outcomes Smoking cessation interventions in pregnancy reduce the proportion of women who continue to smoke in late pregnancy, and reduce low birthweight and preterm birth. Smoking cessation interventions in pregnancy need to be implemented in all maternity care settings. Given the difficulty many pregnant women addicted to tobacco have quitting during pregnancy, population-based measures to reduce smoking and social inequalities should be supported 72 trials are included. 56 RCTs (over 20,000 pregnant women) and 9 cluster-RCTs (over 5000 pregnant women) provided data on smoking cessation outcomes. Significant reduction in smoking in late pregnancy following interventions (risk ratio (RR) 0.94, 95% confidence interval (CI) 0.93 to 0.96), an absolute difference of six in 100 women who stopped smoking during pregnancy. However, there is significant heterogeneity in the combined data (I2 > 60%). In the trials with the lowest risk of bias, the interventions had less effect (RR 0.97, 95% CI 0.94 to 0.99), and lower heterogeneity (I2 = 36%). Eight trials of smoking relapse prevention (over 1000 women) showed no statistically significant reduction in relapse. Smoking cessation interventions reduced low birthweight (RR 0.83, 95% CI 0.73 to 0.95) and + Include
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