immune complexes to the liver and spleen? What is the most efficient cofactor for factor MCP cleavage of C3b? How does MCP also help to control the Since binding of factor B to C3b is inhibited alternative pathway? What is capable of dissociating both classical DAF and alternative pathway C3 convertases? What portion of DAF is covalently attached to a The carboxy-terminal glycophospholipid anchor that is inserted into the outer layer of the membrane lipid bilayer? What is the reason that DAF can C3 arrangement of DAF in the lipid bilayer allows convertase sites that are not immediately DAF mobility within the membrane adjacent to it? What is the reason that the presence of DAF on because foreign do not possess DAF host cells protects them from bystander lysis and is one of the main mechanisms used in discrimination of self from nonself? What is the principal soluble regulator of the factor H alternative pathway? Which factor acts by binding to C3b, thus factor H preventing the binding of factor B? C3b in the fluid phase has a hundredfold greater factor H affinity for which factor than for factor B? On cell surfaces, C3b preferentially binds which Factor B factor? Which factor accelerates the dissociation of the Factor H C3bBb complex on cell surfaces? Which factor acts as a cofactor that allows Factor H factor I to break down C3b Which protein is also known as vitronectin? S protein Which protein interacts with the C5b67 S protein complex as it forms in the fluid phase and prevents it from binding to cell membranes? What causes binding of C8 and C9 to still S protein proceed, but polymerization of C9 does not occur, and the complex is unable to insert itself into the cell membrane or to produce lysis? What also acts to formation of the Membrane inhibitor of reactive lysis (MIRL), or membrane attack complex besides S protein? CD59 What protein’s main function is to bind to C8 Membrane inhibitor of reactive lysis (MIRL), or and prevent insertion of C9 into host cell CD59 membranes? What protein plays an important role as part of CR2 the B-cell coreceptor for antigen?
immune complexes to the liver and spleen? What is the most efficient cofactor for factor cleavage of C3b? MCP How does MCP also help to control the alternative pathway? Since binding of factor B to C3b is inhibited What is capable of dissociating both classical and alternative pathway C3 convertases? DAF What portion of DAF is covalently attached to a glycophospholipid anchor that is inserted into the outer layer of the membrane lipid bilayer? The carboxy-terminal What is the reason that DAF can C3 convertase sites that are not immediately adjacent to it? arrangement of DAF in the lipid bilayer allows DAF mobility within the membrane What is the reason that the presence of DAF on host cells protects them from bystander lysis and is one of the main mechanisms used in discrimination of self from nonself? because foreign do not possess DAF What is the principal soluble regulator of the alternative pathway? factor H Which factor acts by binding to C3b, thus preventing the binding of factor B? factor H C3b in the fluid phase has a hundredfold greater affinity for which factor than for factor B? factor H On cell surfaces, C3b preferentially binds which factor? Factor B Which factor accelerates the dissociation of the C3bBb complex on cell surfaces? Factor H Which factor acts as a cofactor that allows factor I to break down C3b Factor H Which protein is also known as vitronectin? S protein Which protein interacts with the C5b67 complex as it forms in the fluid phase and prevents it from binding to cell membranes? S protein What causes binding of C8 and C9 to still proceed, but polymerization of C9 does not occur, and the complex is unable to insert itself into the cell membrane or to produce lysis? S protein What also acts to formation of the membrane attack complex besides S protein? Membrane inhibitor of reactive lysis (MIRL), or CD59 What protein’s main function is to bind to C8 and prevent insertion of C9 into host cell membranes? Membrane inhibitor of reactive lysis (MIRL), or CD59 What protein plays an important role as part of the B-cell coreceptor for antigen? CR2
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