SIGN: high ≥3 months. Prior to male = 81%; pulse sequence HR for likelihood of having: quality with a low enrolment all patients QRS interval = 136 ± LGE sequence: standard, SCD or survived SCA risk of bias underwent ICA or CTCA to 30 milliseconds; segmented inversion recovery appropriate ICD discharge determine CM aetiology. gradient-echo pulse sequence non-SCD cardiac death LBBB = 44%; Exclusion criteria: standard Contrast agent: in LGE+ patients compared with those contraindications to LVEF (CMR) = 26 ± 7%; mmol/kg Gadovist that are LGE– inclusive of a GFR of ICM = 48%; ≤30 mL/min/1.73 m2 Time delay: 10–15 minutes HR for likelihood of having: primary prevention ICD = LV function: Cine images were SCD or survived SCA 56%; examined to determine the LV appropriate ICD discharge end-systolic volume, LV secondary prevention ICD = volume and LV mass by 8%; cardiac death (not SCD) semi-automated endocardial and CRT-D implantation = 36%; in NIDCM patients compared with ICM epicardial contour tracing. patients NYHA class = 2.5 ± 0.9; LGE diagnosis: The presence or absence of any LGE was visually medications: ACE inhibitor = determined by an experienced 71%, ARB = 25%, -blockers blinded CMR interpreter, and the = 80% most dominant pattern scored: N=59 patients with ICM: 1) subendocardial based all LGE+ 2) mid-wall N=65 patients with NIDCM: 3) subepicardial. n=46 (71%) LGE+ n=19 (29%) LGE– Mean follow-up: 632 ± 262 days Gulati et al. Prospective N=472 consecutive patients Inclusion criteria: patients Scanner: 1.5-T scanner and a ICD implantation: Not described () cohort with DCM confirmed by CMR with DCM of at least standardised protocol Outcomes: 6 months’ duration and
SIGN: high quality with a low risk of bias male = 81%; QRS interval = 136 ± 30 milliseconds; LBBB = 44%; LVEF (CMR) = 26 ± 7%; ICM = 48%; primary prevention ICD = 56%; secondary prevention ICD = 8%; CRT-D implantation = 36%; NYHA class = 2.5 ± 0.9; medications: ACE inhibitor = 71%, ARB = 25%, -blockers = 80% N=59 patients with ICM: all LGE+ N=65 patients with NIDCM: n=46 (71%) LGE+ n=19 (29%) LGE– Mean follow-up: 632 ± 262 days ≥3 months. Prior to enrolment all patients underwent ICA or CTCA to determine CM aetiology. Exclusion criteria: standard contraindications to inclusive of a GFR of ≤30 mL/min/1.73 m2 pulse sequence LGE sequence: standard, segmented inversion recovery gradient-echo pulse sequence Contrast agent: mmol/kg Gadovist Time delay: 10–15 minutes LV function: Cine images were examined to determine the LV end-systolic volume, LV volume and LV mass by semi-automated endocardial and epicardial contour tracing. LGE diagnosis: The presence or absence of any LGE was visually determined by an experienced blinded CMR interpreter, and the most dominant pattern scored: 1) subendocardial based 2) mid-wall 3) subepicardial. HR for likelihood of having: SCD or survived SCA appropriate ICD discharge non-SCD cardiac death in LGE+ patients compared with those that are LGE– HR for likelihood of having: SCD or survived SCA appropriate ICD discharge cardiac death (not SCD) in NIDCM patients compared with ICM patients Gulati et al. () Prospective cohort N=472 consecutive patients with DCM confirmed by CMR Inclusion criteria: patients with DCM of at least 6 months’ duration and Scanner: 1.5-T scanner and a standardised protocol ICD implantation: Not described Outcomes:
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