21. Explain how exposure to intense sunshine or tanning lamps can increase a person's risk of developing melanoma. 22. Some people inherit a mutation that causes their cells to have defective DNA repair mechanisms. Explain why these people have an increased risk of cancer. This figure shows how, over a lifetime, mutations can accumulate in a cell line (a cell and its descendants). The development of a cancer requires the accumulation of multiple mutations in a single cell line. Mutations that contribute to the development of cancer are relatively rare, so it typically takes decades for a cell line to accumulate the multiple mutations that cause cancer. 1 (From: Stratton, M. R. (2013), Journeys into the genome of cancer cells. EMBO Mol Med, 5: 169–172. doi:10.1002/emmm.201202388). 23. Give two examples of environmental and lifestyle exposures that can increase a risk of person’s cancer. 24. Explain how your behavior as a teenager (e.g. high exposure to the UV in sunlight or tanning beds) can affect your risk of developing cancer decades later as an older adult. 25. If a cell is unable to repair DNA damage, molecular processes within the cell may result in cell suicide (programmed cell death). When a cell in your body has DNA damage that the cell cannot repair, how could cell suicide be helpful?
21. Explain how exposure to intense sunshine or tanning lamps can increase a person's risk of developing melanoma. 22. Some people inherit a mutation that causes their cells to have defective DNA repair mechanisms. Explain why these people have an increased risk of cancer. This figure shows how, over a lifetime, mutations can accumulate in a cell line (a cell and its descendants). The development of a cancer requires the accumulation of multiple mutations in a single cell line. Mutations that contribute to the development of cancer are relatively rare, so it typically takes decades for a cell line to accumulate the multiple mutations that cause cancer. 1 (From: Stratton, M. R. (2013), Journeys into the genome of cancer cells. EMBO Mol Med, 5: 169–172. doi:10.1002/emmm.201202388). 23. Give two examples of environmental and lifestyle exposures that can increase a person’s risk of cancer. 24. Explain how your behavior as a teenager (e.g. high exposure to the UV in sunlight or tanning beds) can affect your risk of developing cancer decades later as an older adult. 25. If a cell is unable to repair DNA damage, molecular processes within the cell may result in cell suicide (programmed cell death). When a cell in your body has DNA damage that the cell cannot repair, how could cell suicide be helpful?
HaloferaxUVUnivProtocol.docx