Sahin et al. (2015) 480 6.9% 0.6% 6.2% . . Turkey Solberg et al. (2011) 875 . . . 21% . Pain 64% Norway, Sweden Utrera et al. (2011a) 220 . . . Mild 24.1 %, . Bacteraemia 4.5% Spain Intense 0.9% Bacteriuria 4.5% Fever 3.2% Hospitalisation 0.5% Utrera et al. (2011b) 144 . 0.7% . 5.6% 0.7% Prostatitis 1.4% Spain Rectal bleeding 0.7% Loeb et al. (2013) 2,243 . . . . 27.9-63.0% Haematospermia 6.0-13.8% (Systematic review) patients Rectal bleeding 11.5-39.0% Erectile dysfunction 2.2-91.3% (11 studies) UTI = urinary tract infection, . = not reported. Table Safety of trans-perineal biopsy Study ID Patients Infection Urinary Haematuria Hospitalisation Mild haematuria Others obstruction Mai et al. (2016) 3,007 0.03% 1.9% 47% 2.1% 0.1% Haematospermia 6.1% China Perineal haematoma 0.5% Rectal bleeding 0% Chang et al. (2013) 8,044 patients 0.0% 0.4-38.0% 0.2-57.0% 0.7-1.4% . UTI 1.1-8.0% Systematic review (34 studies) Fever 1.0-5.3% Loeb et al. (2013) 3,203 patients 0.0% 1.6-20.6% 0.3-5.2% . 3.7-45.3% . Systematic review (17 studies) UTI = urinary tract infection, NR. = not reported
Sahin et al. (2015) Turkey 480 6.9% 0.6% 6.2% . . Solberg et al. (2011) Norway, Sweden 875 . . . 21% . Pain 64% Utrera et al. (2011a) Spain 220 . . . Mild 24.1 %, Intense 0.9% . Bacteraemia 4.5% Bacteriuria 4.5% Fever 3.2% Hospitalisation 0.5% Utrera et al. (2011b) Spain 144 . 0.7% . 5.6% 0.7% Prostatitis 1.4% Rectal bleeding 0.7% Loeb et al. (2013) (Systematic review) 2,243 patients (11 studies) . . . . 27.9-63.0% Haematospermia 6.0-13.8% Rectal bleeding 11.5-39.0% Erectile dysfunction 2.2-91.3% UTI = urinary tract infection, . = not reported. Table Safety of trans-perineal biopsy Study ID Patients Infection Urinary obstruction Haematuria Hospitalisation Mild haematuria Others Mai et al. (2016) China 3,007 0.03% 1.9% 47% 2.1% 0.1% Haematospermia 6.1% Perineal haematoma 0.5% Rectal bleeding 0% Chang et al. (2013) Systematic review 8,044 patients (34 studies) 0.0% 0.4-38.0% 0.2-57.0% 0.7-1.4% . UTI 1.1-8.0% Fever 1.0-5.3% Loeb et al. (2013) Systematic review 3,203 patients (17 studies) 0.0% 1.6-20.6% 0.3-5.2% . 3.7-45.3% . UTI = urinary tract infection, NR. = not reported
1397_Final_MSAC_Assessment_Report.docx