Table S1: Changes in volumetry in NPC patients compared to controls. ROI analysis found significantly decreased volumes in NPC patients in the corpus callosum, the basal ganglia and the superior cerebral peduncle in particular. m : mean; SD : standard deviation; min : minimum; max : maximum, L : left; R: right. NPC Controls ROI p (m% ± SD min-max) (m% ± SD min-max) 3rd Ventricle 0.1±0.04 0.07±0.01 0.003 0.04-0.2 0.04-0.1 4th Ventricle 0.2±0.04 0.1±0.05 0.019 0.1-0.2 0.09-0.3 L 0.3±0.1 0.4±0.04 0.002 0.1-0.6 0.3-0.4 Putamen R 0.3±0.1 0.4±0.04 0.009 0.1-0.5 0.3-0.4 L 0.2±0.05 0.2±0.02 0.022 0.2-0.3 0.2-0.3 Caudate R 0.2±0.07 0.3±0.02 0.022 0.1-0.4 0.2-0.3 L 0.4±0.08 0.5±0.03 <0.001 0.3-0.6 0.4-0.6 Thalamus R 0.4±0.05 0.5±0.02 <0.001 0.3-0.4 0.46-0.53 Anterior Corpus callosum 0.04 ± 0.01 0.06±0.01 0.006 0.02-0.07 0.04-0.09 Superior Cerebral Peduncle 0.01 ±0.002 0.02±0.002 0.029 0.01-0.02 0.01-0.02
Table S1: Changes in volumetry in NPC patients compared to controls. ROI analysis found significantly decreased volumes in NPC patients in the corpus callosum, the basal ganglia and the superior cerebral peduncle in particular. m : mean; SD : standard deviation; min : minimum; max : maximum, L : left; R: right. ROI NPC (m% ± SD min-max) Controls (m% ± SD min-max) p 3rd Ventricle 0.1±0.04 0.04-0.2 0.07±0.01 0.04-0.1 0.003 4th Ventricle 0.2±0.04 0.1-0.2 0.1±0.05 0.09-0.3 0.019 Putamen L 0.3±0.1 0.1-0.6 0.4±0.04 0.3-0.4 0.002 R 0.3±0.1 0.1-0.5 0.4±0.04 0.3-0.4 0.009 Caudate L 0.2±0.05 0.2-0.3 0.2±0.02 0.2-0.3 0.022 R 0.2±0.07 0.1-0.4 0.3±0.02 0.2-0.3 0.022 Thalamus L 0.4±0.08 0.3-0.6 0.5±0.03 0.4-0.6 <0.001 R 0.4±0.05 0.3-0.4 0.5±0.02 0.46-0.53 <0.001 Anterior Corpus callosum 0.04 ± 0.01 0.02-0.07 0.06±0.01 0.04-0.09 0.006 Superior Cerebral Peduncle 0.01 ±0.002 0.01-0.02 0.02±0.002 0.01-0.02 0.029
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