Baldotto 2013 Conference Brazil EGFR mutation Retrospective 189 of 336 May PCR; Sanger Cytological TATO abstract testing in study of EGFR screened May 2013 sequencing samples and NSCLC testing in one tumour tissue; centre after unclear how introduction of much was reflex testing; archival single centre Cankovic 2013a, Conference US EGFR mutation Four phase 111 cases tested Mar 2011-Sept Not reported Not reported TATO b abstract and ALK exercise to 2012 translocation streamline testing in process from NSCLC pre-analytic to reporting phase of molecular testing for EGFR/ALK mutations Ellis 2013 Full journal Canada EGFR mutation Prospective 2104 test Tests RT-PCR Blocks or Test failures article testing in validation/QC requests requested slides; not TATO advanced exercise for between Mar specified RATRS implementation 2010-Dec whether TATRR NSCLC of routine EGFR 2010 testing was on testing strategy newly in NSCLC acquired, involving 5 archive tissue testing or either laboratories Arriola 2014 Conference Spain EGFR mutation Retrospective 181 evaluable Patients RT-PCR Mainly biopsy TATO abstract in advanced observation patients diagnosed material NSCLC study of the 2010-Dec management 2011 patterns of advanced EGFR mutated NSCLC pts in
Baldotto 2013 Conference abstract Brazil EGFR mutation testing in NSCLC Retrospective study of EGFR testing in one centre after introduction of reflex testing; single centre 189 of 336 screened May May 2013 PCR; Sanger sequencing Cytological samples and tumour tissue; unclear how much was archival TATO Cankovic 2013a, b Conference abstract US EGFR mutation and ALK translocation testing in NSCLC Four phase exercise to streamline process from pre-analytic to reporting phase of molecular testing for EGFR/ALK mutations 111 cases tested Mar 2011-Sept 2012 Not reported Not reported TATO Ellis 2013 Full journal article Canada EGFR mutation testing in advanced NSCLC Prospective validation/QC exercise for implementation of routine EGFR testing strategy in NSCLC involving 5 testing laboratories 2104 test requests Tests requested between Mar 2010-Dec 2010 RT-PCR Blocks or slides; not specified whether testing was on newly acquired, archive tissue or either Test failures TATO RATRS TATRR Arriola 2014 Conference abstract Spain EGFR mutation in advanced NSCLC Retrospective observation study of the management patterns of advanced EGFR mutated NSCLC pts in 181 evaluable patients Patients diagnosed 2010-Dec 2011 RT-PCR Mainly biopsy material TATO
1331-Contracted_Assessment_Report-accessible.docx