van Dijk 2008 Cutaneous Cases with no initial diagnosis 160/1837 (8.7%) Expert pathology panel unable to provide 67/1837 (3.6%) melanocytic lesions specific diagnosis Cases with a differential diagnosis 435/1837 (23.7%) Expert pathology panel unable to provide 42/1837 (2.3%) N=1837 Cases with a provisional diagnosis 1217/1837 (66.2%) specific diagnosis but able to provide a presumed working diagnosis Expert pathology panel unable to provide 25/1837 (1.4%) specific diagnosis but able to provide a presumed working diagnosis + advice for further diagnostic and/or therapeutic procedures Veenhuizen 1997 Skin lesions Cases with no initial diagnosis 90/1069 (8.4%) Expert or expert pathology panel unable to 7/1069 (0.7%) provide a diagnosis N=1069 Cases with a differential diagnosis 131/1069 (12.3%) Expert or expert pathology panel able to 23/1069 (2.2%) Cases with a provisional diagnosis 798/1069 (74.6%) provide differential diagnosis Expert pathology panel provided 81/90 (90.0%) unequivocal diagnosis in cases with no initial diagnosis Expert pathology panel provided 122/131 (93.1%) unequivocal diagnosis in cases with initial differential diagnosis ORAL AND - - - - - MAXILLOFACIAL Jones 2010 Oral and Cases with no initial diagnosis 7/142 (4.9%) NR NR maxillofacial Cases with a provisional diagnosis 135/142 (95.1%) pathology N=142 cases UROTHELIAL - - - - - Tavora 2009 Urothelial lesions of Cases with no initial diagnosis 0/76 (0%) NR NR the renal pelvis and Cases with a provisional diagnosis 76/76 (100%) mid-upper ureter N=76 LUNG - - - - - Hutton Klein 2010 Granulomatous or Cases with no initial diagnosis 25/80 (31.3%) Expert pathologist provided a confident 27/100 (27.0%)g giant cell reactions diagnosis Cases with a provisional diagnosis 55/80 (68.8%) in the lung Expert pathologist provided a probable 34/100 (34.0%)g (strongly favoured) diagnosis
van Dijk 2008 Cutaneous melanocytic lesions N=1837 Cases with no initial diagnosis Cases with a differential diagnosis Cases with a provisional diagnosis 160/1837 (8.7%) 435/1837 (23.7%) 1217/1837 (66.2%) Expert pathology panel unable to provide specific diagnosis Expert pathology panel unable to provide specific diagnosis but able to provide a presumed working diagnosis Expert pathology panel unable to provide specific diagnosis but able to provide a presumed working diagnosis + advice for further diagnostic and/or therapeutic procedures 67/1837 (3.6%) 42/1837 (2.3%) 25/1837 (1.4%) Veenhuizen 1997 Skin lesions N=1069 Cases with no initial diagnosis Cases with a differential diagnosis Cases with a provisional diagnosis 90/1069 (8.4%) 131/1069 (12.3%) 798/1069 (74.6%) Expert or expert pathology panel unable to provide a diagnosis Expert or expert pathology panel able to provide differential diagnosis Expert pathology panel provided unequivocal diagnosis in cases with no initial diagnosis Expert pathology panel provided unequivocal diagnosis in cases with initial differential diagnosis 7/1069 (0.7%) 23/1069 (2.2%) 81/90 (90.0%) 122/131 (93.1%) ORAL AND MAXILLOFACIAL - - - - - Jones 2010 Oral and maxillofacial pathology N=142 cases Cases with no initial diagnosis Cases with a provisional diagnosis 7/142 (4.9%) 135/142 (95.1%) NR NR UROTHELIAL - - - - - Tavora 2009 Urothelial lesions of the renal pelvis and mid-upper ureter N=76 Cases with no initial diagnosis Cases with a provisional diagnosis 0/76 (0%) 76/76 (100%) NR NR LUNG - - - - - Hutton Klein 2010 Granulomatous or giant cell reactions in the lung Cases with no initial diagnosis Cases with a provisional diagnosis 25/80 (31.3%) 55/80 (68.8%) Expert pathologist provided a confident diagnosis Expert pathologist provided a probable (strongly favoured) diagnosis 27/100 (27.0%)g 34/100 (34.0%)g
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