Norway, Solberg et al. (2011) No RCT II n: 875 TRUSGB Urinary obstruction Sweden Consecutive Age: 66.1 (5.9) Cores: NR Pain Multiple Prospective PSA: 16 (8-27) Enema: 0 hospitals Prior biopsy: 100 Needle: NR Utrera et al. (2011a) No Case series IV Spain n: 220 TRUSGB Urinary obstruction Non-consecutive Tertiary Age: 69.5 (7.9) Cores: 13.5 (1.7) Bacteraemia hospital Bacteriuria Prospective PSA: 12.7 (28.7) Enema: 100 Fever Prior biopsy: mix Needle: NR Hospitalisation Utrera et al. (2011b) No Case series IV Spain n: 144 TRUSGB Major infection Non-consecutive Tertiary Age: 66 (6.4) Cores: 30.4 (3.8) Urinary obstruction hospital Retrospective PSA: 14.4 (12.6) Enema: 100 Haematuria Prior biopsy: 100 Needle: NR Prostatitis Rectal bleeding Loeb et al. (2013) No Systematic review IV USA n: 11 studies, 2,705 patients TRUSGB Haematuria NR Multiple Age: NR Cores: NR Haematospermia hospitals Rectal bleeding NR PSA: NR Enema: NR Erectile dysfunction Prior biopsy: NR Needle: NR a: Describes consecutive or non-consecutive enrolment. b: Describes a retrospective or prospective study design. c: Source: = not reported, PSA = prostate specific antigen, TRUSGB = trans-rectal ultrasound guided biopsy, RCT = randomised controlled trial, UTI = urinary tract infection, PICO = participant intervention comparator outcome.
Solberg et al. (2011) No RCT Consecutive Prospective II Norway, Sweden Multiple hospitals n: 875 Age: 66.1 (5.9) PSA: 16 (8-27) Prior biopsy: 100 TRUSGB Cores: NR Enema: 0 Needle: NR Urinary obstruction Pain Utrera et al. (2011a) No Case series Non-consecutive Prospective IV Spain Tertiary hospital n: 220 Age: 69.5 (7.9) PSA: 12.7 (28.7) Prior biopsy: mix TRUSGB Cores: 13.5 (1.7) Enema: 100 Needle: NR Urinary obstruction Bacteraemia Bacteriuria Fever Hospitalisation Utrera et al. (2011b) No Case series Non-consecutive Retrospective IV Spain Tertiary hospital n: 144 Age: 66 (6.4) PSA: 14.4 (12.6) Prior biopsy: 100 TRUSGB Cores: 30.4 (3.8) Enema: 100 Needle: NR Major infection Urinary obstruction Haematuria Prostatitis Rectal bleeding Loeb et al. (2013) No Systematic review NR NR IV USA Multiple hospitals n: 11 studies, 2,705 patients Age: NR PSA: NR Prior biopsy: NR TRUSGB Cores: NR Enema: NR Needle: NR Haematuria Haematospermia Rectal bleeding Erectile dysfunction a: Describes consecutive or non-consecutive enrolment. b: Describes a retrospective or prospective study design. c: Source: = not reported, PSA = prostate specific antigen, TRUSGB = trans-rectal ultrasound guided biopsy, RCT = randomised controlled trial, UTI = urinary tract infection, PICO = participant intervention comparator outcome.
1397_Final_MSAC_Assessment_Report.docx