IIA 2.5.1.3 DACO The 13C-NMR and 1H-NMR spectra were NMR spectrum 2.13.2 obtained using of chemical …. Assignments of active shifts were reported in and are consistent with … substance the structure. IIA 2.5.1.4 DACO The mass spectrum for the PAI was obtained MS spectrum 2.13.2 using The interpretation of the signals was … of active reported in and is consistent with the structure. … substance IIA 2.5.1.6 The ratio of the enantiomers in the TGAI was Optical purity determined to be obtained using …, … of active substance / optical isomer ratio DACO IIA 2.5.2 Refer to confidential section of this review Spectra for 2.13.2 relevant impurities (i.e. of toxicological concern) IIA 2.6 OECD 105, The water solubility of the active ingredient was Solubility in DACO determined using The results are reported … 2.14.7, below: water OPPTS pH solubility (units) at …°C 830.7840, OPPTS 830.7860
IIA 2.5.1.3 NMR spectrum of active substance DACO 2.13.2 The 13C-NMR and 1H-NMR spectra were obtained using …. Assignments of chemical shifts were reported in … and are consistent with the structure. IIA 2.5.1.4 MS spectrum of active substance DACO 2.13.2 The mass spectrum for the PAI was obtained using … The interpretation of the signals was reported in … and is consistent with the structure. IIA 2.5.1.6 Optical purity of active substance / optical isomer ratio The ratio of the enantiomers in the TGAI was determined to be …, obtained using … IIA 2.5.2 Spectra for relevant impurities (i.e. of toxicological concern) DACO 2.13.2 Refer to confidential section of this review IIA 2.6 Solubility in water OECD 105, DACO 2.14.7, OPPTS 830.7840, OPPTS 830.7860 The water solubility of the active ingredient was determined using … The results are reported below: pH solubility (units) at …°C
final-tg-active-ingredient-product-chemistry-may-2016.docx