Laboratory testing If applicable, continue Confirm the diagnosis by Re-bleed animal or Confirm the diagnosis by routine testing of vectors repeating PCR tests on chicken, considering need repeating tests on for presence of MVEV the positive sample or by for extra number of previous serum samples virus culture and samples, consider (if available), first positive isolation, consider interstate reference and convalescent interstate reference testing if indicated. samples, arrange for testing if applicable Confirm diagnosis by convalescent samples if repeating tests on single bleed has been previous weeks samples, reported; consider the first positive test and reference testing if serum from repeat indicated bleeds; and referring specimens to human reference laboratories Surveillance Assess information from other surveillance mechanisms; consider targeted or enhanced surveillance of human cases or animal seroconversions Vector control Consider escalation of existing mosquito control activities or implementation of integrated mosquito management to reduce larvae and adult vectors (Appendix 3 details emergency vector control response options) Surveillance signal Abnormal numbers of Detection of MVEV in Recent MVEV Evidence of recent vectors mosquitoes seroconversion in MVEV infection in animals humans Communication Stakeholders and partners Notify Public Health Unit Notify Public Health Unit Notify Chief Health Notify Chief Health and/or State/Territory and/or State/Territory Officer or delegate Officer or delegate health department health department
Laboratory testing If applicable, continue routine testing of vectors for presence of MVEV Confirm the diagnosis by repeating PCR tests on the positive sample or by virus culture and isolation, consider interstate reference testing if applicable Re-bleed animal or chicken, considering need for extra number of samples, consider interstate reference testing if indicated. Confirm diagnosis by repeating tests on previous weeks samples, the first positive test and serum from repeat bleeds; and referring specimens to human reference laboratories Confirm the diagnosis by repeating tests on previous serum samples (if available), first positive and convalescent samples, arrange for convalescent samples if single bleed has been reported; consider reference testing if indicated Surveillance Assess information from other surveillance mechanisms; consider targeted or enhanced surveillance of human cases or animal seroconversions Vector control Consider escalation of existing mosquito control activities or implementation of integrated mosquito management to reduce larvae and adult vectors (Appendix 3 details emergency vector control response options) Surveillance signal Abnormal numbers of vectors Detection of MVEV in mosquitoes Recent MVEV seroconversion in animals Evidence of recent MVEV infection in humans Communication Stakeholders and partners Notify Public Health Unit and/or State/Territory health department Notify Public Health Unit and/or State/Territory health department Notify Chief Health Officer or delegate Notify Chief Health Officer or delegate
framework-mvev-2013v2.docx