Similarly, possible to unrealistic draw any -The variations in the conclusions summary base-case model on the benefit inputs were robustness of measure was required for TD the estimate the median to be cost-saving measures, time to the over UC. owing to the initial lack of definitive information. intervention. This was The two-way obtained Validity of sensitivity analysis using a estimate of revealed that the modelling measure of three variables approach. benefit that showed the potential of having -Indirect The summary thresholds cost was benefit (although at very only measure was extreme values) accounted specific to the were the for in the intervention probability of a sensitivity considered in TD patient being analysis. the study and scheduled for a is not clinic visit, clinic comparable visit cost, and -It was with the travel cost. assumed that benefits of a other health dermatology care clinic visit interventions. would take a The inclusion of
-The summary benefit measure was the median time to the initial definitive intervention. This was obtained using a modelling approach. -Indirect cost was only accounted for in the sensitivity analysis. -It was assumed that a dermatology clinic visit would take a Similarly, unrealistic variations in the base-case model inputs were required for TD to be cost-saving over UC. The two-way sensitivity analysis revealed that the three variables that showed the potential of having thresholds (although at very extreme values) were the probability of a TD patient being scheduled for a clinic visit, clinic visit cost, and travel cost. The inclusion of possible to draw any conclusions on the robustness of the estimate measures, owing to the lack of information. Validity of estimate of measure of benefit The summary benefit measure was specific to the intervention considered in the study and is not comparable with the benefits of other health care interventions.
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