The evidence from suggests that gastrointestinal damage occurs in a very small proportion of SLE patients. and Figure 9 show that gastrointestinal system damage occurs early in the disease. The rate of damage accrual after the first year of the disease is relatively low. illustrates that damage in the musculoskeletal system is common in SLE patients. Petri et al. (170) find that avascular necrosis (osteonecrosis) as the most common musculoskeletal complication in SLE patients affecting 14.5% of patients. Table 18 reports the odds ratios for logistic regression for musculoskeletal damage and related events. Table : Odds ratios with confidence intervals estimated for risk factors for musculoskeletal damage First Date Damage outcome Disease Age Steroids Immunosuppressants Arthritis Author Activity name Stoll (179) 2001 Musculoskeletal 2.26 0.885 damage (OR) (0.65–10.32) (0.78–1.00) Gladman 2001 Osteonecrosis 18.5 2.7 4.2 (199) (OR) (3.2-359.6) (1.02-8.8) (1.6-13.7) 2006 Osteonecrosis 1.03 3.04 (OR) (1.00-1.05) (1.02 (200) OR Odds ratios
The evidence from suggests that gastrointestinal damage occurs in a very small proportion of SLE patients. and Figure 9 show that gastrointestinal system damage occurs early in the disease. The rate of damage accrual after the first year of the disease is relatively low. illustrates that damage in the musculoskeletal system is common in SLE patients. Petri et al. (170) find that avascular necrosis (osteonecrosis) as the most common musculoskeletal complication in SLE patients affecting 14.5% of patients. Table 18 reports the odds ratios for logistic regression for musculoskeletal damage and related events. Table : Odds ratios with confidence intervals estimated for risk factors for musculoskeletal damage First Author name Date Damage outcome Disease Activity Age Steroids Immunosuppressants Arthritis Stoll (179) 2001 Musculoskeletal damage (OR) 2.26 (0.65–10.32) 0.885 (0.78–1.00) Gladman (199) 2001 Osteonecrosis (OR) 18.5 (3.2-359.6) 2.7 (1.02-8.8) 4.2 (1.6-13.7) (200) 2006 Osteonecrosis (OR) 1.03 (1.00-1.05) 3.04 (1.02 OR Odds ratios
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