The Protocol Advisory Sub-Committee (PASC) is a standing sub-committee of MSAC. Its primary objective is the determination of protocols to guide clinical and economic assessments of medical interventions proposed for public funding. Purpose of this document This document is intended to provide a protocol that will be used to guide the assessment of an intervention for a particular population of patients. Protocols are finalised after inviting relevant stakeholders to provide input. The protocol guiding the assessment of the health intervention has been developed using the widely accepted “PICO” approach. The PICO approach involves a clear articulation of the following aspects of the research question that the assessment is intended to answer: Patients – specification of the characteristics of the patients in whom the intervention is to be considered for use; Intervention – specification of the proposed intervention Comparator – specification of the therapy most likely to be replaced by the proposed intervention Outcomes – specification of the health outcomes and the healthcare resources likely to be affected by the introduction of the proposed intervention Purpose of application An application requesting Medicare Benefits Schedule (MBS) listing primarily of breast MRI to guide treatment in women newly diagnosed with breast cancer was received from Breast Surgeons of Australia and New Zealand Incorporated (BreastSurgANZ) by the Department of Health and Ageing in September 2012. The use of breast MRI is proposed to offer improved local staging and/or early treatment monitoring and planning. The proposed indications are: women newly diagnosed with breast cancer and undergoing preoperative (neo-adjuvant) chemotherapy women newly diagnosed with the lobular subtype of breast cancer women newly diagnosed with breast cancer who are aged <50 years and/or have very dense breasts which preclude mammographic assessment, and/or have a significant size discrepancy (≥1 cm) between mammogram and ultrasound findings have suspicious/malignant calcifications which may underestimate the extent of ductal carcinoma in situ (DCIS) disease
The Protocol Advisory Sub-Committee (PASC) is a standing sub-committee of MSAC. Its primary objective is the determination of protocols to guide clinical and economic assessments of medical interventions proposed for public funding. Purpose of this document This document is intended to provide a protocol that will be used to guide the assessment of an intervention for a particular population of patients. Protocols are finalised after inviting relevant stakeholders to provide input. The protocol guiding the assessment of the health intervention has been developed using the widely accepted “PICO” approach. The PICO approach involves a clear articulation of the following aspects of the research question that the assessment is intended to answer: Patients – specification of the characteristics of the patients in whom the intervention is to be considered for use; Intervention – specification of the proposed intervention Comparator – specification of the therapy most likely to be replaced by the proposed intervention Outcomes – specification of the health outcomes and the healthcare resources likely to be affected by the introduction of the proposed intervention Purpose of application An application requesting Medicare Benefits Schedule (MBS) listing primarily of breast MRI to guide treatment in women newly diagnosed with breast cancer was received from Breast Surgeons of Australia and New Zealand Incorporated (BreastSurgANZ) by the Department of Health and Ageing in September 2012. The use of breast MRI is proposed to offer improved local staging and/or early treatment monitoring and planning. The proposed indications are: women newly diagnosed with breast cancer and undergoing preoperative (neo-adjuvant) chemotherapy women newly diagnosed with the lobular subtype of breast cancer women newly diagnosed with breast cancer who are aged <50 years and/or have very dense breasts which preclude mammographic assessment, and/or have a significant size discrepancy (≥1 cm) between mammogram and ultrasound findings have suspicious/malignant calcifications which may underestimate the extent of ductal carcinoma in situ (DCIS) disease
1333-Breast-MRI-FinalProtocol-Accessible.DOCX