Baseline 1 (B1) Test when exposure-free for 30 days Baseline 2 (B2) Re-test 3-14 days later, exposure-free Baseline 3 (B3) Re-test only if (B1)-(B2) exceeds 20% Average of Baseline Compare test results results to Baseline results Test date RBC Plasma Timing Comment Cholinesterase Cholinesterase % fall in (kU/L) (kU/L) cholinesterase Pre-shift Post-shift Pre-shift Post-shift Pre-shift Post-shift Note: Baseline Ideally two pre-exposure tests should be performed at least three days apart, no sooner than 30 days after – prior exposure. Reliability is indicated by the two tests being within 10% of each other. Periodic testing should occur during the period of organophosphate pesticide use (latter half of work day). 20% fall in cholinesterase Re-test ≥ – 40% fall in cholinesterase Remove from exposure until test results return to baseline level. ≥ – 6B Urinary metabolite test (dialkyl phosphate (DAP) metabolites) – Test date Timing Comment Urinary DAP metabolites (µmol/mol creatinine) Pre-shift Post-shift Next day Pre-shift Post-shift Next day Pre-shift Post-shift Next day Note: <100 µmol/mol creatinine considered low work exposure. – 100-1000 µmol/mol creatinine indicates work exposure review workplace controls to reduce exposure levels. – – >1000 µmol/mol creatinine indicates high work exposure; may be associated with a fall in blood cholinesterase levels. – RECOMMENDATIONS (by Medical Practitioner) () all relevant boxes Suitable for work with organophosphate pesticides Counselling required
Baseline 1 (B1) Test when exposure-free for 30 days Baseline 2 (B2) Re-test 3-14 days later, exposure-free Baseline 3 (B3) Re-test only if (B1)-(B2) exceeds 20% Average of Baseline results Compare test results to Baseline results Test date RBC Cholinesterase (kU/L) Plasma Cholinesterase (kU/L) Timing Comment % fall in cholinesterase Pre-shift Post-shift Pre-shift Post-shift Pre-shift Post-shift Note: Baseline – Ideally two pre-exposure tests should be performed at least three days apart, no sooner than 30 days after prior exposure. Reliability is indicated by the two tests being within 10% of each other. Periodic testing should occur during the period of organophosphate pesticide use (latter half of work day). ≥ 20% fall in cholinesterase – Re-test ≥ 40% fall in cholinesterase – Remove from exposure until test results return to baseline level. 6B – Urinary metabolite test (dialkyl phosphate (DAP) metabolites) Test date Urinary DAP metabolites (µmol/mol creatinine) Timing Comment Pre-shift Post-shift Next day Pre-shift Post-shift Next day Pre-shift Post-shift Next day Note: <100 µmol/mol creatinine – considered low work exposure. 100-1000 µmol/mol creatinine – indicates work exposure – review workplace controls to reduce exposure levels. >1000 µmol/mol creatinine – indicates high work exposure; may be associated with a fall in blood cholinesterase levels. RECOMMENDATIONS (by Medical Practitioner) () all relevant boxes Suitable for work with organophosphate pesticides Counselling required
hazardous-chemicals-requiring-health-monitoring.docx