Table 3 – Predictive ability of modifications to the GRACE score in COPD patients Method for obtaining M-H pooled RR C-statistic Hosmer-Lemshow predicted risk of (95% CI) for death death at 6 months adjusted for predicted risk of death Normal GRACE score 1.29 (1.28-1.33) 0.8166 >0.999 (comparator for 1) 1. Normal GRACE 0.99 (0.96-1.01) 0.8181 >0.999 score – multiply risk of (p<0.001)* death by 1.3 for COPD patients MINAP derived 1.23 (1.20-1.26) 0.8322 >0.999 GRACE score (comparator for 2-3) 2. MINAP derived 1.20 (1.17-1.23) 0.8323 >0.999 GRACE score + (p=0.274)* smoking 3. MINAP derived 1.00 (0.94-1.02) 0.8333 >0.999 GRACE score + COPD (p<0.001)* *p-values compare the C-statistics for the modified models compared to either the normal GRACE score or the MINAP derived GRACE score.
Table 3 – Predictive ability of modifications to the GRACE score in COPD patients Method for obtaining predicted risk of death M-H pooled RR (95% CI) for death at 6 months adjusted for predicted risk of death C-statistic Hosmer-Lemshow Normal GRACE score (comparator for 1) 1.29 (1.28-1.33) 0.8166 >0.999 1. Normal GRACE score – multiply risk of death by 1.3 for COPD patients 0.99 (0.96-1.01) 0.8181 (p<0.001)* >0.999 MINAP derived GRACE score (comparator for 2-3) 1.23 (1.20-1.26) 0.8322 >0.999 2. MINAP derived GRACE score + smoking 1.20 (1.17-1.23) 0.8323 (p=0.274)* >0.999 3. MINAP derived GRACE score + COPD 1.00 (0.94-1.02) 0.8333 (p<0.001)* >0.999 *p-values compare the C-statistics for the modified models compared to either the normal GRACE score or the MINAP derived GRACE score.
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