Belfiore et al (2013) Retrospective CS Patients with primary or secondary lung cancer who were Intervention: CT-guided 1. Adverse events: non-specified not suitable for surgical procedures due to tumour extension MTA Italy Level IV or concomitant disease Conscious sedation Risk of bias: High N = 56 (69) Duration: 6–10 minutes Hospital setting Maximum diameter mean (SD): 30 (9) Comparator: N/A NR M/F ratio: 35:21 Mean age (SD): 61.5 (9.13) years 44 patients had lung cancer (31 adenocarcinomas, 10 squamous carcinomas, 3 small cell carcinomas). 12 patients had metastatic disease (9 had primary colorectal cancer and 3 had primary breast cancer) Carafiello et al Retrospective CS Patients with NSCLC stages IA-IV or metastases, all Intervention: CT-guided 1. Safety: defined as the frequency of intra-, peri- and (2014) patients judged to be inoperable or refusing surgery MTA adverse events. All patients were evaluated for Level IV the presence of post ablation syndrome. Pain was Italy N = 24 (26) Conscious sedation Risk of bias: High evaluated with VAS Mean index of max diameter (range): 30.96 (8–100) mm Duration: NR Hospital setting M/F ratio: 15:9 Comparator: N/A mean (range): 9.9 months (3–26) Mean age (range): 71.7 (46–83) years Primary cancers were: 6 squamous cell, 7 adenocarcinomas, 1 neuroendocrine carcinoma. There were 11 metastases and 1 microcytoma.
Belfiore et al (2013) Italy Retrospective CS Level IV Risk of bias: High Hospital setting NR Patients with primary or secondary lung cancer who were not suitable for surgical procedures due to tumour extension or concomitant disease N = 56 (69) Maximum diameter mean (SD): 30 (9) M/F ratio: 35:21 Mean age (SD): 61.5 (9.13) years 44 patients had lung cancer (31 adenocarcinomas, 10 squamous carcinomas, 3 small cell carcinomas). 12 patients had metastatic disease (9 had primary colorectal cancer and 3 had primary breast cancer) Intervention: CT-guided MTA Conscious sedation Duration: 6–10 minutes Comparator: N/A 1. Adverse events: non-specified Carafiello et al (2014) Italy Retrospective CS Level IV Risk of bias: High Hospital setting mean (range): 9.9 months (3–26) Patients with NSCLC stages IA-IV or metastases, all patients judged to be inoperable or refusing surgery N = 24 (26) Mean index of max diameter (range): 30.96 (8–100) mm M/F ratio: 15:9 Mean age (range): 71.7 (46–83) years Primary cancers were: 6 squamous cell, 7 adenocarcinomas, 1 neuroendocrine carcinoma. There were 11 metastases and 1 microcytoma. Intervention: CT-guided MTA Conscious sedation Duration: NR Comparator: N/A 1. Safety: defined as the frequency of intra-, peri- and adverse events. All patients were evaluated for the presence of post ablation syndrome. Pain was evaluated with VAS
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