FISH Requirements Maximum Average Referral Tests Quantity Container Transit Turnaround Price Time Time Amniotic Fluid, Blood, Chorionic Villus Sampling (CVS) 55 Trisomy 13 [Patau Syndrome] Trisomy 18 [Edward’s Syndrome] 55 Amniotic Fluid in 55 Trisomy 21 [Down’s Syndrome] Universal container or conical 55 Rapid sexing ( X and Y ) tube, (sterile, plastic) 200 Prader Willi Li-Heparin 1 - 2 Within 3 ml bottle / working 24 hours EDTA days whole Digeorge 200 blood (sterile, plastic) 400 Miller Dieker CVS in media (sterile, Trisomy 21, XY 95 plastic) Trisomy 13, 18 and 21 130 155 Trisomy 13, 18, 21 and XY Preimplantation Genetic Diagnosis (PGD) Fixated Salinated Within 24 50 For each N/A PGD Blastomere Slide hours embryo Bone Marrow and Unstimulated Blood 70 BCR/ABL: t(9;22) [CML/ALL] 100 GLI: (12q13) [CLL] 100 ATM: (11q22) [CLL] Li-Heparin 100 p53: (17p13) [CLL] bottle 24 hours 100 1 - 2 ml (sterile, 2 - 3 days DLEU: 13q14 [CLL] plastic) 100 ETO/AML: t(8;21) [AML/M2] 100 CBFB: inv(16) [AML/M4] 100 PML/RARA: t(15;17) [AML/M3] 100 TEL/AML: t(12;21) [ALL]
FISH Requirements Tests Quantity Container Maximum Transit Time Average Turnaround Time Referral Price Amniotic Fluid, Blood, Chorionic Villus Sampling (CVS) Trisomy 13 [Patau Syndrome] 3 ml Amniotic Fluid in Universal container or conical tube, (sterile, plastic) Li-Heparin bottle / EDTA whole blood (sterile, plastic) CVS in media (sterile, plastic) Within 24 hours 1 - 2 working days 55 Trisomy 18 [Edward’s Syndrome] 55 Trisomy 21 [Down’s Syndrome] 55 Rapid sexing ( X and Y ) 55 Prader Willi 200 Digeorge 200 Miller Dieker 400 Trisomy 21, XY 95 Trisomy 13, 18 and 21 130 Trisomy 13, 18, 21 and XY 155 Preimplantation Genetic Diagnosis (PGD) PGD Fixated Blastomere Salinated Slide N/A Within 24 hours 50 For each embryo Bone Marrow and Unstimulated Blood BCR/ABL: t(9;22) [CML/ALL] 1 - 2 ml Li-Heparin bottle (sterile, plastic) 24 hours 2 - 3 days 70 GLI: (12q13) [CLL] 100 ATM: (11q22) [CLL] 100 p53: (17p13) [CLL] 100 DLEU: 13q14 [CLL] 100 ETO/AML: t(8;21) [AML/M2] 100 CBFB: inv(16) [AML/M4] 100 PML/RARA: t(15;17) [AML/M3] 100 TEL/AML: t(12;21) [ALL] 100
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