short arms of some chromosomes that is of no clinical significance. These variations are known as ‘polymorphic variants’, ‘polymorphisms’ or ‘normal variants’. In a few cases, it is necessary to distinguish between such variation and a true abnormality. It may therefore be necessary to karyotype the parents or to carry out further tests on a repeat sample. On rare instances, technical limitations associated with some of the technologies used may be present. Cytogenetics Tests Karyotyping Requirements Specimen Quantity Container Maximum Transit Referral Turnaround Time Time Price Peripheral Li-Heparin bottle (sterile, 2 – 4 ml 48 hours 7 days 43 blood vacutainer, plastic) Fetal Li-Heparin bottle (sterile, 0.5 – 1 ml 48 hours 7 days 43 blood/Cord plastic) Bone marrow and Li-Heparin bottle (sterile, 2 - 5 ml 24 hours 5 days 55 unstimulated plastic) blood Universal container or 16 Amniotic Fluid 15 – 20 ml 24 hours 14 days 75 ml conical tube (sterile, plastic) Chorionic Universal container Villus 2 - 25 mg 24 hours 14 days 80 (sterile, plastic). In sterile Sampling media. Universal container Products Of Variable 24 hours 14 days 80 (sterile, plastic). In sterile Conception saline.
short arms of some chromosomes that is of no clinical significance. These variations are known as ‘polymorphic variants’, ‘polymorphisms’ or ‘normal variants’. In a few cases, it is necessary to distinguish between such variation and a true abnormality. It may therefore be necessary to karyotype the parents or to carry out further tests on a repeat sample. On rare instances, technical limitations associated with some of the technologies used may be present. Cytogenetics Tests Karyotyping Requirements Specimen Quantity Container Maximum Transit Time Turnaround Time Referral Price Peripheral blood 2 – 4 ml Li-Heparin bottle (sterile, vacutainer, plastic) 48 hours 7 days 43 Fetal blood/Cord 0.5 – 1 ml Li-Heparin bottle (sterile, plastic) 48 hours 7 days 43 Bone marrow and unstimulated blood 2 - 5 ml Li-Heparin bottle (sterile, plastic) 24 hours 5 days 55 Amniotic Fluid 15 – 20 ml Universal container or 16 ml conical tube (sterile, plastic) 24 hours 14 days 75 Chorionic Villus Sampling 2 - 25 mg Universal container (sterile, plastic). In sterile media. 24 hours 14 days 80 Products Of Conception Variable Universal container (sterile, plastic). In sterile saline. 24 hours 14 days 80
1336042047MOLECULAR%20GENETICS%20(word%20doc).docx