Table 12: List of associations between abnormal radiological morphological charactertistics of hip shape and OA. Radiological Study Design Value Definition of Risk of developing OA Association with OA Morphological associated OA Characteristic with risk Lateral Longitudinal case series, 4-29 year f/up, n=18 (20-35 yrs <20 ROA All developed OA (Wiberg, 1939) Edge Angle of age), no OA at baseline (LCEA) Longitudinal case series, n=32 hips (age average 43 yrs), <20 ROA All developed OA (Cooperman et al. no OA at baseline, f/up 22 years 1983) Longitudinal cohort study, cases (n=74, OA before age 65) <16 KL≥2 No controls had a LCEA < 16 (Murphy et al. 1995) versus controls (n=43, no OA before age 65). Cross-sectional cohort study, cases (n=566, all with <20 minJSW≤ OR[95%CIs] = 10.1[2.9-35] (McWilliams et al. unilateral OA) versus controls (n=1108, no OA). 2.5mm 2010) Measurements taken from non-degenerate hip for cases. Longitudinal cohort study, cases (n=58, developed OA by <30 ROA OR[95%CIs] = 3.3[1.1-10.1] (Lane et al. 2000) 8 years) versus controls (n=118, did not develop OA), all females (mean age 70 years), f/up 8 years. Longitudinal cohort study, cases (n= 78, developed OA) <25 KL≥2 OR[95%CIs] = 2.4[1.2-4.7] (Reijman et al. 2005) versus controls (n=757, no OA), mean age 65 years, mean f/up 6.6 years Cross-sectional study, cases (presence of ROA) versus <20 KL≥2 OR[95%CIs] = 3.2[1.7-5.9] (Jacobsen et al. 2005) controls (no ROA), n=3859 total individuals.
Table 12: List of associations between abnormal radiological morphological charactertistics of hip shape and OA. Radiological Morphological Characteristic Study Design Value associated with risk Definition of OA Risk of developing OA Association with OA Lateral Angle (LCEA) Longitudinal case series, 4-29 year f/up, n=18 (20-35 yrs of age), no OA at baseline <20 ROA All developed OA (Wiberg, 1939) Longitudinal case series, n=32 hips (age average 43 yrs), no OA at baseline, f/up 22 years <20 ROA All developed OA (Cooperman et al. 1983) Longitudinal cohort study, cases (n=74, OA before age 65) versus controls (n=43, no OA before age 65). <16 KL≥2 No controls had a LCEA < 16 (Murphy et al. 1995) Cross-sectional cohort study, cases (n=566, all with unilateral OA) versus controls (n=1108, no OA). Measurements taken from non-degenerate hip for cases. <20 minJSW≤ 2.5mm OR[95%CIs] = 10.1[2.9-35] (McWilliams et al. 2010) Longitudinal cohort study, cases (n=58, developed OA by 8 years) versus controls (n=118, did not develop OA), all females (mean age 70 years), f/up 8 years. <30 ROA OR[95%CIs] = 3.3[1.1-10.1] (Lane et al. 2000) Longitudinal cohort study, cases (n= 78, developed OA) versus controls (n=757, no OA), mean age 65 years, mean f/up 6.6 years <25 KL≥2 OR[95%CIs] = 2.4[1.2-4.7] (Reijman et al. 2005) Cross-sectional study, cases (presence of ROA) versus controls (no ROA), n=3859 total individuals. <20 KL≥2 OR[95%CIs] = 3.2[1.7-5.9] (Jacobsen et al. 2005) Edge
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