imipenem MIC 4 Tumbarello Clinical, Meropenem CR Death (colistin alone vs. 11/22 vs. Overall advantage to K. 2012 [] retrospective (all (definitive 2 or 3-drug 12/37 combination. Pneumoniae bacteremia) therapy) combinations including (32%) Colistin-carbapenem colistin-meropenem not specifically combination) examined. 1 Unless otherwise stated, data the carbapenem was combined with colistin 2 Data obtained from Landman 2008 [] CI continuous infusion –
imipenem MIC 4 Tumbarello 2012 [] Clinical, retrospective (all bacteremia) Meropenem (definitive therapy) CR K. Pneumoniae Death (colistin alone vs. 2 or 3-drug combinations including colistin-meropenem combination) 11/22 vs. 12/37 (32%) Overall advantage to combination. Colistin-carbapenem not specifically examined. 1 Unless otherwise stated, data the carbapenem was combined with colistin 2 Data obtained from Landman 2008 [] CI – continuous infusion
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