Cardiovascular Not assessed in 4 0.6% ( 0.1-1.2%) n/a n/a n/a No CRF cities study per 10 ug/m3 Some evidence However, cited recommended. () () from Hong Kong study Random effects epidemiological which showed no No effect in 15-64 years: No estimate. studies but evidence of Australian 2-cities effect 24-hour average. inconsistent threshold for effect meta-analysis (). 65+ years: No effect Weak evidence of toxicological at 5-40ug/m3 () publication bias. studies, and effect 24-hour average. May use the CRF 1-hour maximum CRF not intended estimate not robust () from COMEAP () Lag 01 for health risk to co-pollutant () in a sensitivity Meta-analysis of 2 assessment. adjustment. analysis. cities - Brisbane, () Sydney. Low heterogeneity. ICD9: 390-459; ICD10: I00-I99 (excluding I67.3, I68.0, I88, I97.8, I97.9, I98.0), G45 (excluding G45.3), G46, M30, M31, R58 Cardiac Not assessed in 4 2.4% (1.6-3.3%) per n/a n/a n/a No CRF cities study 10 ug/m3 recommended. () () Random effects No effect in 15-64 years: No estimate. Australian 2-cities effect 24-hour average. meta-analysis (). 65+ years: No effect No evidence of () publication bias. May use the CRF 1-hour maximum. CRF not intended from COMEAP () Lag 01. for health risk in a sensitivity
Cardiovascular Not assessed in 4 cities study () 15-64 years: No effect 65+ years: No effect () 1-hour maximum Lag 01 Meta-analysis of 2 cities - Brisbane, Sydney. Low heterogeneity. ICD9: 390-459; ICD10: I00-I99 (excluding I67.3, I68.0, I88, I97.8, I97.9, I98.0), G45 (excluding G45.3), G46, M30, M31, R58 0.6% ( 0.1-1.2%) per 10 ug/m3 () Random effects estimate. 24-hour average. Weak evidence of publication bias. CRF not intended for health risk assessment. n/a n/a Some evidence from epidemiological studies but inconsistent toxicological studies, and effect estimate not robust to co-pollutant adjustment. () n/a However, cited Hong Kong study which showed no evidence of threshold for effect at 5-40ug/m3 24-hour average. () () No CRF recommended. No effect in Australian 2-cities meta-analysis (). May use the CRF from COMEAP () in a sensitivity analysis. Cardiac Not assessed in 4 cities study () 15-64 years: No effect 65+ years: No effect () 1-hour maximum. Lag 01. 2.4% (1.6-3.3%) per 10 ug/m3 () Random effects estimate. 24-hour average. No evidence of publication bias. CRF not intended for health risk n/a n/a n/a No CRF recommended. No effect in Australian 2-cities meta-analysis (). May use the CRF from COMEAP () in a sensitivity
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