Appendix 4. Example of method differences that prevent harmonisation (Koerbin, July 2013 Harmonisation Workshop)18 GGT Lipase LD g-Glutamyl-3-Carboxy- Spectro - Glutaric Acid IFCC Recommended Modular Ester Method Nitoanilide g-Glutamyl-3-Carboxy- Spectro - Glutaric Acid IFCC Recommended Integra Nitoanilide Ester Method g-Glutamyl-3-Carboxy- Pyruvate >0.7 mmolar Vitros Nitoanilide Spectro-diacetylglycerol (P-L) 1,2-Diglyceride subst./co- Lactate to Pyruvate Au2700 Mod IFCC (Szasz) lipase (NADH) g-Glutamyl-3-Carboxy- Lactate to Pyruvate Abbott Quinone dye Nitoanilide (NADH) g-Glutamyl-3-Carboxy- Spectro - Glutaric Acid Lactate to Pyruvate DxC Nitoanilide Ester (NADH) g-Glutamyl-3-Carboxy- Spectro - Glutaric Acid Lactate to Pyruvate Advia Nitoanilide Ester (NADH)
Appendix 4. Example of method differences that prevent harmonisation (Koerbin, July 2013 Harmonisation Workshop)18 GGT Lipase LD Modular g-Glutamyl-3-Carboxy- Nitoanilide Spectro - Glutaric Acid Ester IFCC Recommended Method Integra g-Glutamyl-3-Carboxy- Nitoanilide Spectro - Glutaric Acid Ester IFCC Recommended Method Vitros g-Glutamyl-3-Carboxy- Nitoanilide Spectro-diacetylglycerol Pyruvate >0.7 mmolar (P-L) Au2700 Mod IFCC (Szasz) 1,2-Diglyceride subst./co- lipase Lactate to Pyruvate (NADH) Abbott g-Glutamyl-3-Carboxy- Nitoanilide Quinone dye Lactate to Pyruvate (NADH) DxC g-Glutamyl-3-Carboxy- Nitoanilide Spectro - Glutaric Acid Ester Lactate to Pyruvate (NADH) Advia g-Glutamyl-3-Carboxy- Nitoanilide Spectro - Glutaric Acid Ester Lactate to Pyruvate (NADH)
Harmonisation.docx