weeks (W) STEP HVTN 071 Merck Ad5 HIV-1 Ad5: W0, 4, 26 NCT00095576 NCT00486408 Gag/Pol/Nef (clade B) [5] Sample: W52 & Phambili n = 16 (MRKAd5) NCT00413725 VRC multiclade HIV-1 DNA plasmid (clade B IAVI V001 group Gag/Pol/Nef, clades DNA: W0, 4, 8 C ABC Env) & multiclade Ad5: W24 HVTN 505 [8,11,12] NCT00124007* Ad5 vector (expressing NCT00865566 n = 12 same genes without Sample: W30, Nef) 48 (VRC DNA/Ad5) ALVAC-HIV (vCP1521) vCP1521: W0, RV135 & VaxGen gp120 4, 12, 24 NCT Not RV144 (clades B/E ) AIDSVAX: W12, [15,16,46] available NCT00223080 (ALVAC/AIDSVAX) 24 n = 21 Sample: W28 *Equivalent regimen also tested in clinical trial HVTN 204, NCT00125970 Abbreviations NCT: National clinical trial, information at , a service of the U.S. National Institutes of Health PU: Particle units
weeks (W) HVTN 071 NCT00486408 n = 16 Merck Ad5 HIV-1 Gag/Pol/Nef (clade B) (MRKAd5) Ad5: W0, 4, 26 Sample: W52 STEP NCT00095576 & Phambili NCT00413725 [5] IAVI V001 group C NCT00124007* n = 12 VRC multiclade HIV-1 DNA plasmid (clade B Gag/Pol/Nef, clades ABC Env) & multiclade Ad5 vector (expressing same genes without Nef) (VRC DNA/Ad5) DNA: W0, 4, 8 Ad5: W24 Sample: W30, 48 HVTN 505 NCT00865566 [8,11,12] RV135 NCT Not available n = 21 ALVAC-HIV (vCP1521) & VaxGen gp120 (clades B/E ) (ALVAC/AIDSVAX) vCP1521: W0, 4, 12, 24 AIDSVAX: W12, 24 Sample: W28 RV144 NCT00223080 [15,16,46] *Equivalent regimen also tested in clinical trial HVTN 204, NCT00125970 Abbreviations NCT: National clinical trial, information at , a service of the U.S. National Institutes of Health PU: Particle units
Hayes%20Adenovirus%20resubmission%20manuscript%20260216.docx