Table 8. Published manuscripts reporting 18F-FMISO human imaging studies mCi injected MBq injected Year Clinical Condition N Reference Narita 2012 Glioma 2 12.2 450 (Japan 2012) Toma-dasu 10 370 2012 Head & Neck Cancer 7 (Belgium 2012) Hirata 10.8 400 2012 Glioma 23 (Japan 2012) 0.1 mCi/kg 3.7 MBq/kg Yamamoto 2012 Glioma 30 (Japan 2012) Max 7 Max 260 Mammar 0.14 mCi/kg 5 MBq/kg 2012 Skull Base Chordoma 7 (France 2012) Yasuda 10.8 400 2012 Head & Neck Cancer 40 (Japan 2012) Chen 0.2 + 0.05 mCi/kg 7.3 + 1.7 MBq/kg 2012 Head & Neck Cancer 12 (USA 2012) Zips 6.8-8.1 250-300 2012 Head & Neck Cancer 25 (Germany 2012) 0.1 mCi/kg 3.7 MBq/kg McKeage 2012 Various cancers 17 (New Zealand 2012) <10 <370 5.3-9.4 197-348 Kawai 2011 Glioma 10 (Japan 2011) Median = 8.3 Median = 308 Non-Small Cell Lung Vera 0.05 mCi/kg 2.0 MBq/kg 2011 5 Cancer (France 2011) Eary 7 259 2011 Sarcoma 10 (USA 2011) Head & Neck 13.7-19.4 510-718 Kikuchi 2011 Squamous Cell 17 (Japan 2011) Mean 16 Median=592 Carcinoma 0.1 mCi/kg 3.7 MBq/kg Hendrickson 2011 Head & Neck Cancer 10 (USA 2011) Max 7 Max 370 De Clermont 307 2011 Glioma 1 8.3 (France 2011) Hugonnet 0.14 mCi/kg 5 MBq/kg 2011 Renal Cell Carcinoma 53 (France 2011) Abolmaali 6.9 256 + 37 2011 Head and Neck Cancer 23 (Germany 2011) Head & Neck 13.7-19.4 510-718 Yamane 2011 Squamous Cell 13 (Japan 2010) Mean 16 Median= 592 Carcinoma Choi 20 740 2010 Head & Neck Cancer 8 (Korea 2010)
Table 8. Published manuscripts reporting 18F-FMISO human imaging studies Year Clinical Condition N mCi injected MBq injected Reference 2012 Glioma 2 12.2 450 Narita (Japan 2012) 2012 Head & Neck Cancer 7 10 370 Toma-dasu (Belgium 2012) 2012 Glioma 23 10.8 400 Hirata (Japan 2012) 2012 Glioma 30 0.1 mCi/kg Max 7 3.7 MBq/kg Max 260 Yamamoto (Japan 2012) 2012 Skull Base Chordoma 7 0.14 mCi/kg 5 MBq/kg Mammar (France 2012) 2012 Head & Neck Cancer 40 10.8 400 Yasuda (Japan 2012) 2012 Head & Neck Cancer 12 0.2 + 0.05 mCi/kg 7.3 + 1.7 MBq/kg Chen (USA 2012) 2012 Head & Neck Cancer 25 6.8-8.1 250-300 Zips (Germany 2012) 2012 Various cancers 17 0.1 mCi/kg <10 3.7 MBq/kg <370 McKeage (New Zealand 2012) 2011 Glioma 10 5.3-9.4 Median = 8.3 197-348 Median = 308 Kawai (Japan 2011) 2011 Non-Small Cell Lung Cancer 5 0.05 mCi/kg 2.0 MBq/kg Vera (France 2011) 2011 Sarcoma 10 7 259 Eary (USA 2011) 2011 Head & Neck Squamous Cell Carcinoma 17 13.7-19.4 Mean 16 510-718 Median=592 Kikuchi (Japan 2011) 2011 Head & Neck Cancer 10 0.1 mCi/kg Max 7 3.7 MBq/kg Max 370 Hendrickson (USA 2011) 2011 Glioma 1 8.3 307 De Clermont (France 2011) 2011 Renal Cell Carcinoma 53 0.14 mCi/kg 5 MBq/kg Hugonnet (France 2011) 2011 Head and Neck Cancer 23 6.9 256 + 37 Abolmaali (Germany 2011) 2011 Head & Neck Squamous Cell Carcinoma 13 13.7-19.4 Mean 16 510-718 Median= 592 Yamane (Japan 2010) 2010 Head & Neck Cancer 8 20 740 Choi (Korea 2010)
FMISO_IB_2013_WORD.docx