Felker et al. No Case series III-2 USA n: 49 3.0T 2 Fellowship TRUSGB + TP, TN, NA (2016) trained cog-MRI FP, FN Retrospective Tertiary Age: mean 65 (range 47-80) Coil: NR genitourinary hospital Consecutive PSA: median 5 (IQR 2.5-6.4) Contrast: NR radiologists with Gleason: 6 >1,000 mpMRIs experience Margel et al. Single TRUSGB + TP, TN, No Case series III-2 Canada n: 60 1.5T NA (2012) experienced cog-MRI FP, FN Prospective Tertiary Age: G1 mean 62.6 (SD 7), G2 Coil: PPAC + radiologist hospital mean 63.5 (SD 6), G3 mean 64 (SD ERC Consecutive 8.2) Contrast: PSA: G1 median 5.9 (range 1.7-10), G2 median 4.4 (range 1.1-9.1), G3 median 4.1 (range 1.1-9.9) acid Gleason: ≤ 6 Mullins et al. No Case series III-2 USA n: 37 3.0T Single TRUSGB TP, TN, NA 2013 radiologists with FP, FN Retrospective Tertiary Age: median 67 (range 49-80) Coil: body coil + >10 years’ hospital ERC Consecutive PSA: median 4.5 (range 0.4-18.6) experience in Contrast: Gleason: ≤ 6 prostate MRI gadopentetate Sahibzada et No Case series III-2 UK n: 100 1.5T or 3.0T Single TRUSGB TP, TN, NA al. 2016 radiologists with FP, FN Retrospective Tertiary Age: mean 69.8 (range 59.1-85.9) Coil: NR >10 years’ hospital Consecutive PSA: mean 6.5 (range 3.4-17.5) Contrast: NR experience in Gleason: ≤ 6 prostate MRI
Felker et al. (2016) No Case series Retrospective Consecutive III-2 USA Tertiary hospital n: 49 Age: mean 65 (range 47-80) PSA: median 5 (IQR 2.5-6.4) Gleason: 6 3.0T Coil: NR Contrast: NR 2 Fellowship trained genitourinary radiologists with >1,000 mpMRIs experience TRUSGB + cog-MRI TP, TN, FP, FN NA Margel et al. (2012) No Case series Prospective Consecutive III-2 Canada Tertiary hospital n: 60 Age: G1 mean 62.6 (SD 7), G2 mean 63.5 (SD 6), G3 mean 64 (SD 8.2) PSA: G1 median 5.9 (range 1.7-10), G2 median 4.4 (range 1.1-9.1), G3 median 4.1 (range 1.1-9.9) Gleason: ≤ 6 1.5T Coil: PPAC + ERC Contrast: acid Single experienced radiologist TRUSGB + cog-MRI TP, TN, FP, FN NA Mullins et al. 2013 No Case series Retrospective Consecutive III-2 USA Tertiary hospital n: 37 Age: median 67 (range 49-80) PSA: median 4.5 (range 0.4-18.6) Gleason: ≤ 6 3.0T Coil: body coil + ERC Contrast: gadopentetate Single radiologists with >10 years’ experience in prostate MRI TRUSGB TP, TN, FP, FN NA Sahibzada et al. 2016 No Case series Retrospective Consecutive III-2 UK Tertiary hospital n: 100 Age: mean 69.8 (range 59.1-85.9) PSA: mean 6.5 (range 3.4-17.5) Gleason: ≤ 6 1.5T or 3.0T Coil: NR Contrast: NR Single radiologists with >10 years’ experience in prostate MRI TRUSGB TP, TN, FP, FN NA
1397_Final_MSAC_Assessment_Report.docx