SUPPLEMENTARY MATERIAL New pregnane glycoside derivative from (Ehrenb) Caralluma retrospiciens Mahmoud Fahmi Elsebaia,c,*, Ietidal EL-Tahir Mohamedb aDepartment of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt. bDepartment of Botany, Faculty of Science, University of Khartoum, Khartoum, Sudan. cDepartment of Chemistry, University of Oulu, Oulu, Finland. * Corresponding authors: Mahmoud Fahmi Elsebai: Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt. Tel: 2 Fax+2-050- 2247496. E-mail: elsebai72@yahoo.com Abstract Retrospinoside (1) is a new polyoxypregnane glycoside which was isolated and characterised from the aerial parts of (Ehrenb.) N. E. Caralluma retrospiciens Br., family Apocynaceae. The structure was established as 4β-pregnane. Its structural elucidation was performed through extensive spectroscopic measurements including 1D- and 2D-NMR, and HRMS, in addition to chemical methods. plant natural products; pregnane glycosides; polyoxypregnanes; Keywords: Caralluma retrospiciens
SUPPLEMENTARY MATERIAL New pregnane glycoside derivative from Caralluma retrospiciens (Ehrenb) Mahmoud Fahmi Elsebaia,c,*, Ietidal EL-Tahir Mohamedb aDepartment of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt. bDepartment of Botany, Faculty of Science, University of Khartoum, Khartoum, Sudan. cDepartment of Chemistry, University of Oulu, Oulu, Finland. * Corresponding authors: Mahmoud Fahmi Elsebai: Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt. Tel: Fax+2-050- 2247496. E-mail: elsebai72@yahoo.com Abstract Retrospinoside (1) is a new polyoxypregnane glycoside which was isolated and characterised from the aerial parts of Caralluma retrospiciens (Ehrenb.) N. E. Br., family Apocynaceae. The structure was established as 4β-pregnane. Its structural elucidation was performed through extensive spectroscopic measurements including 1D- and 2D-NMR, and HRMS, in addition to chemical methods. Keywords: plant natural products; pregnane glycosides; polyoxypregnanes; Caralluma retrospiciens 2
gnpl_a_1003186_sm6944.docx