Co-Beneldopa Dopamine. Can be Dyskinesia used at all stages of Drowsiness the disease process. Hallucinations Works well on Postural hypotension stiffness and bradykinesia Dopamine Agonist Pramipexole Stimulates post Nausea/vomiting Ropinerole synaptic Hallucinations dopaminergic Impulse Control receptors Disorder Confusion Monoamine Selegiline Slows the Drug is a stimulant, Rasagiline metabolism of therefore should be oxidase type B (MAO-B) inhibitors Dopamine taken in the morning COMT inhibitors Entacapone Blocks the Will increase side Stalevo metabolism of effects of L-dopa Dopamine Anticholinergics Trihexyphenidyl Blocks the action of Limited efficacy (Benzhexol) Acetylcholine (which Neuro-psychiatric breaks down side effects Dopamine) Amantadine Enhances the Mild effect Glutamate Agonist release of Dopamine. Short lived Anticholinergic Insomnia properties Appendix 2 COMMONLY USED DRUGS TO AVOID If patient already stabilised on therapy review and monitor Table highlighting drugs to avoid (and use) when treating hallucinations and nausea: Drug Treatment of Treatment of Vigilance is Hallucinations Nausea / Vomiting required with the /Confusion use of
Co-Beneldopa Dopamine. Can be used at all stages of the disease process. Works well on stiffness and bradykinesia Dyskinesia Drowsiness Hallucinations Postural hypotension Dopamine Agonist Pramipexole Ropinerole Stimulates post synaptic dopaminergic receptors Nausea/vomiting Hallucinations Impulse Control Disorder Confusion Monoamine oxidase type B (MAO-B) inhibitors Selegiline Rasagiline Slows the metabolism of Dopamine Drug is a stimulant, therefore should be taken in the morning COMT inhibitors Entacapone Stalevo Blocks the metabolism of Dopamine Will increase side effects of L-dopa Anticholinergics Trihexyphenidyl (Benzhexol) Blocks the action of Acetylcholine (which breaks down Dopamine) Limited efficacy Neuro-psychiatric side effects Glutamate Agonist Amantadine Enhances the release of Dopamine. Anticholinergic properties Mild effect Short lived Insomnia Appendix 2 COMMONLY USED DRUGS TO AVOID If patient already stabilised on therapy review and monitor Table highlighting drugs to avoid (and use) when treating hallucinations and nausea: Drug Treatment of Hallucinations /Confusion Treatment of Nausea / Vomiting Vigilance is required with the use of
Guideline%20-%20swallowing%20ACE%20Jan%202015.docx