Table Profiles of studies on Surgery included in the systematic literature review Study design Author Level of evidence Study population characteristics: (Year) Risk of bias A N (lesions, tumour size, male/female ratio, age, Relevant outcomes: measurement and methods Location Median follow-up B prior therapy, primary cancer (P2/3 only) Description of Intervention and Comparator of analysis POPULAITON 2 Renaud et al Retrospective CS Lung metastases originating from a CRC who Intervention: surgical resection 1. Postoperative mortality: death occurring during (2014) underwent resection with curative intent hospitalisation or within 30 days of surgery Level IV N = 320 (median number of resected lesions=2) 2. Overall survival: Kaplan-Meier test Risk of bias: High Comparator: NA Tumour size NR 21.6 months (0–192) M/F ratio: 215:105 Median age: 63 (IQR: 13.75) years Primary cancer: colon - 164/320 patients (51%), rectum - 156/320 patients (49%)
Table Profiles of studies on Surgery included in the systematic literature review Author (Year) Location Study design Level of evidence Risk of bias A Median follow-up B Study population characteristics: N (lesions, tumour size, male/female ratio, age, prior therapy, primary cancer (P2/3 only) Description of Intervention and Comparator Relevant outcomes: measurement and methods of analysis POPULAITON 2 Renaud et al (2014) Retrospective CS Level IV Risk of bias: High 21.6 months (0–192) Lung metastases originating from a CRC who underwent resection with curative intent N = 320 (median number of resected lesions=2) Tumour size NR M/F ratio: 215:105 Median age: 63 (IQR: 13.75) years Primary cancer: colon - 164/320 patients (51%), rectum - 156/320 patients (49%) Intervention: surgical resection Comparator: NA 1. Postoperative mortality: death occurring during hospitalisation or within 30 days of surgery 2. Overall survival: Kaplan-Meier test
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