we become aware of illness. CB5h Antibiotics B5.16 Explain that antibiotics can 1) Write the word Explain to students that many Clinical trials are a only be used to treat 'antibiotic' in the middle plants contain substances that application of the bacterial infections because of the board, then give help protect them against idea of a fair test that they inhibit cell processes in students a minute or two attack by microorganisms. students use in their the bacterium but not the in pairs or small groups Some of these have been own work. Help host organism to think of related words developed into medicines to students to compare the B5.20 Describe that the process of or terms. help treat our diseases. Make way they carry out their developing new medicines, sure that students understand practical investigations including antibiotics, has 2) Tell students that a that a clear area around a disc and the way clinical many stages including new medicine is being indicates where bacteria have trials by discussing the discovery, development, developed to help people been killed. following aspects: preclinical and clinical testing suffering from a particular disease. Ask Bacterial lawn plates and plant Trial size/ sample size students to work in pairs extracts will need preparing or small groups to jot before the lesson. Suitable Using controls down the questions that extracts include: chilli powder, need answering during cinnamon, cloves, fennel, placebos and 'blind' the development. garlic, paprika, pepper, thyme. trials (more able To make an extract, grind 3 g students only) crushed or ground plant material with 10 cm3 ethanol Digital: TBC (IDA) and shake vigorously for 10 minutes. Give each group two of the plant extracts to use. Results for all extracts will need to be compared across the class.
we become aware of illness. CB5h Antibiotics B5.16 B5.20 Explain that antibiotics can only be used to treat bacterial infections because they inhibit cell processes in the bacterium but not the host organism Describe that the process of developing new medicines, including antibiotics, has many stages including discovery, development, preclinical and clinical testing 1) Write the word 'antibiotic' in the middle of the board, then give students a minute or two in pairs or small groups to think of related words or terms. 2) Tell students that a new medicine is being developed to help people suffering from a particular disease. Ask students to work in pairs or small groups to jot down the questions that need answering during the development. Explain to students that many plants contain substances that help protect them against attack by microorganisms. Some of these have been developed into medicines to help treat our diseases. Make sure that students understand that a clear area around a disc indicates where bacteria have been killed. Bacterial lawn plates and plant extracts will need preparing before the lesson. Suitable extracts include: chilli powder, cinnamon, cloves, fennel, garlic, paprika, pepper, thyme. To make an extract, grind 3 g crushed or ground plant material with 10 cm3 ethanol (IDA) and shake vigorously for 10 minutes. Give each group two of the plant extracts to use. Results for all extracts will need to be compared across the class. Clinical trials are a application of the idea of a fair test that students use in their own work. Help students to compare the way they carry out their practical investigations and the way clinical trials by discussing the following aspects: Trial size/ sample size Using controls placebos and 'blind' trials (more able students only) Digital: TBC
gcse-science-planning-document-term-3.docx