NCT02799303 A Randomized Clinical ≤ 50 years of age Sunnybrook NR 3 years Not yet June 2020 III-2 Trial Comparing the Health Sciences open for Other Efficacy of MRI Versus Centre Canada PSA for Prostate Cancer Screening: The MVP Study (MRI vs PSA) Serial mpMRI Scanning in Men with biopsy University Not yet January III-3, NCT02721784 10 6 months Prostate Cancer After confirmed PCa who had College, London open for 2018 diagnostic Population 2 Androgen Deprivation mpMRI scan of the case-control UK Therapy and prostate pre-biopsy study RadioTherapy (SMART) NCT02524860 Targeted Prostate Biopsy Candidates for fusion Focal NR 1 year Not yet July 2016 III-3, Using a Novel biopsy; Elevated PSA open for diagnostic Healthcare Inc. Population 1 Fusion Device levels; mpMRI with lesions case-control Canada in Patients With an having a Prostate Imaging study Elevated PSA and a Reporting and Data Positive Multiparametric System (PI-RADS) score MRI greater than or equal to 3 NCT02380027 PRostate Evaluation for Suspicious PSA and DRE University 470 1 month Recruiting September III-2, single Clinically Important College, London 2017 blind RCT Population 1 Disease: Sampling Using UK Image-guidance Or Not? (PRECISION) NCT02745496 Multiparametric Magnetic Men aged 40-75 years, University of 600 4 years Recruiting January III-2 Resonance Imaging with suspicious PSA Dundee 2019 Population 1 Characterization and and/or DRE UK Guided Biopsy of the Prostate in Men Suspected of Having Prostate Cancer NCT02678481 MR-targeted vs. Random Patients with negative Fondazione del 90 3 months Recruiting August III-2 TRUS-guided Prostate biopsy Piemonte per 2016 Other Biopsy in Patients With l'Oncologia Italy
NCT02799303 Other Canada A Randomized Clinical Trial Comparing the Efficacy of MRI Versus PSA for Prostate Cancer Screening: The MVP Study (MRI vs PSA) ≤ 50 years of age Sunnybrook Health Sciences Centre NR 3 years Not yet open for June 2020 III-2 NCT02721784 Population 2 UK Serial mpMRI Scanning in Prostate Cancer After Androgen Deprivation Therapy and RadioTherapy (SMART) Men with biopsy confirmed PCa who had mpMRI scan of the prostate pre-biopsy University College, London 10 6 months Not yet open for January 2018 III-3, diagnostic case-control study NCT02524860 Population 1 Canada Targeted Prostate Biopsy Using a Novel Fusion Device in Patients With an Elevated PSA and a Positive Multiparametric MRI Candidates for fusion biopsy; Elevated PSA levels; mpMRI with lesions having a Prostate Imaging Reporting and Data System (PI-RADS) score greater than or equal to 3 Focal Healthcare Inc. NR 1 year Not yet open for July 2016 III-3, diagnostic case-control study NCT02380027 Population 1 UK PRostate Evaluation for Clinically Important Disease: Sampling Using Image-guidance Or Not? (PRECISION) Suspicious PSA and DRE University College, London 470 1 month Recruiting September 2017 III-2, single blind RCT NCT02745496 Population 1 UK Multiparametric Magnetic Resonance Imaging Characterization and Guided Biopsy of the Prostate in Men Suspected of Having Prostate Cancer Men aged 40-75 years, with suspicious PSA and/or DRE University of Dundee 600 4 years Recruiting January 2019 III-2 NCT02678481 Other Italy MR-targeted vs. Random TRUS-guided Prostate Biopsy in Patients With Patients with negative biopsy Fondazione del Piemonte per l'Oncologia 90 3 months Recruiting August 2016 III-2
1397_Final_MSAC_Assessment_Report.docx