Study Level Study population Inclusion criteria / Exclusion criteria / Study Outcomes assessed for change in Quality appraisal Objective management Bruder et al. (2013) Level IV: 3,511 patients Inclusion criteria: CMR imaging Myocarditis/CM indication: undergoing CMR for Europe (57 centres in Quality: good Consecutive patients undergoing CMR 88% of patients Total (out of 11,040): myocarditis/CM according to the received a 15 countries) (31.9% of total who Risk of bias: low Completely new diagnoses ACCF/ACR/SCCT/SCMR/ASNC/NASCI/SIR contrast underwent CMR) consensus appropriateness criteria for CMR agent Therapeutic consequences: Patient imaging, in centres included in the (1.28 mmol/kg Prospective - changes in medication characteristics: EuroCMR registry bodyweight) multicentre cohort - invasive procedure age (years) Exclusion criteria: study - hospital discharge <44 58.2%, NR 45–59 32.5%, - hospital admission 60–74 21.2%, Impact on management (new diagnosis >75 14.5% Objective: and/or therapeutic procedure) Evaluate indications, image quality, safety Non-invasive imaging ordered after CMR: and impact on patient management of routine CMR imaging in Europe transthoracic Echo - - transoesophageal Echo - computed tomography Imaging failure rate Note that results are not separated for myocarditis and other CMs. Taylor, AJ et al. Level IV Total number of Inclusion criteria: CMR imaging: Number of cardiac surgical interventions scans = 732 Scanner 1.5-T, averted by CMR (defined as the number of (2013) Quality: Good All patients referred to the Alfred Hospital, cardiac coil, planned interventions who at 6 months Number of CM Melbourne, Australia for clinical CMR electrocardiographic post CMR did not undergo, and had no Australia Risk of bias: low scans = 488 (67%) between 1 July 2007 and 30 June 2009, gating plan to undergo, the intervention that was referred and funded a under 4 pre-specified Prospective planned prior to CMR scanning) For CM: clinical pathways: CM, viability, Data collection observational study, tumour/mass and ARVC instrument: Change to device plan single centre Patient Questionnaire sent characteristics:
Study Level Quality appraisal Study population Inclusion criteria / Exclusion criteria / Objective Study Outcomes assessed for change in management Bruder et al. (2013) Europe (57 centres in 15 countries) Prospective multicentre cohort study Level IV: Quality: good Risk of bias: low 3,511 patients undergoing CMR for myocarditis/CM (31.9% of total who underwent CMR) Patient characteristics: age (years) <44 58.2%, 45–59 32.5%, 60–74 21.2%, >75 14.5% Inclusion criteria: Consecutive patients undergoing CMR according to the ACCF/ACR/SCCT/SCMR/ASNC/NASCI/SIR consensus appropriateness criteria for CMR imaging, in centres included in the EuroCMR registry Exclusion criteria: NR Objective: Evaluate indications, image quality, safety and impact on patient management of routine CMR imaging in Europe CMR imaging 88% of patients received a contrast agent (1.28 mmol/kg bodyweight) Myocarditis/CM indication: Total (out of 11,040): Completely new diagnoses Therapeutic consequences: - changes in medication - invasive procedure - hospital discharge - hospital admission Impact on management (new diagnosis and/or therapeutic procedure) Non-invasive imaging ordered after CMR: - transthoracic Echo - transoesophageal Echo - computed tomography Imaging failure rate Note that results are not separated for myocarditis and other CMs. Taylor, AJ et al. (2013) Australia Prospective observational study, single centre Level IV Quality: Good Risk of bias: low Total number of scans = 732 Number of CM scans = 488 (67%) For CM: Patient characteristics: Inclusion criteria: All patients referred to the Alfred Hospital, Melbourne, Australia for clinical CMR between 1 July 2007 and 30 June 2009, referred and funded a under 4 pre-specified clinical pathways: CM, viability, tumour/mass and ARVC CMR imaging: Scanner 1.5-T, cardiac coil, electrocardiographic gating Data collection instrument: Questionnaire sent Number of cardiac surgical interventions averted by CMR (defined as the number of planned interventions who at 6 months post CMR did not undergo, and had no plan to undergo, the intervention that was planned prior to CMR scanning) Change to device plan
1393-CMRforDCM.docx