<35% and NYHA class II or Cardiac function sequence: Cine techniques at a median of 16 days without sustained VT: III without sustained VT, who images were acquired with a following the CMR. The ICD devices Japan NHMRC level n=122 (70%) LGE+ were referred with HF at their steady-state, free-precession were programmed to detect VF and VT. n=53 (30%) LGE– initial visit between January sequence in long-axis planes and Outcomes: 2005 and June 2014 contiguous short-axis slices. n=7 patients received an ICD n=17 patients received a HR for likelihood of having: Exclusion criteria: LGE sequence: SIGN: high CRT-D contraindications to CMR gradient-echo sequence quality with a low ICD implantation existed, including significant appropriate ICD therapy risk of bias Patient characteristics: Contrast agent: 0.1 mmol/kg renal dysfunction (GFR of life-threatening arrhythmic events age = 60 ± 15 years; ≤30 mL/min/1.73 m2) and in LGE+ patients compared with those implanted devices such as Time delay: 10 minutes male = 63%; that are LGE– pacemakers and/or LV function: Details not reported QRS interval = 121 ± defibrillators 31 milliseconds; LGE diagnosis: The presence or absence of LGE was visually LBBB = 33%; determined by 2 independent LVEF (Echo) = 29 ± 5.4%; blinded readers and divided into 6 presence of AF = 17%; groups according to the LGE pattern: documentation of VT = 5%; 1) septal subendocardial NYHA class: II = 31%, III = 69%; 2) lateral subendocardial medications: ACE 3) septal mid-wall, inhibitor/ARB = 95%, 4) lateral mid-wall = 94% 5) septal subepicardial Mean follow-up: 5.1 ± 3.3 years 6) lateral subepicardial 7) papillary muscle pattern. Cho et al. () Prospective N=79 patients with Inclusion criteria: patients Scanner: Gyroscan Intera system ICD implantation: Presence or with ECG-proven LV systolic
Japan NHMRC level SIGN: high quality with a low risk of bias without sustained VT: n=122 (70%) LGE+ n=53 (30%) LGE– n=7 patients received an ICD n=17 patients received a CRT-D Patient characteristics: age = 60 ± 15 years; male = 63%; QRS interval = 121 ± 31 milliseconds; LBBB = 33%; LVEF (Echo) = 29 ± 5.4%; presence of AF = 17%; documentation of VT = 5%; NYHA class: II = 31%, III = 69%; medications: ACE inhibitor/ARB = 95%, = 94% Mean follow-up: 5.1 ± 3.3 years <35% and NYHA class II or III without sustained VT, who were referred with HF at their initial visit between January 2005 and June 2014 Exclusion criteria: contraindications to CMR existed, including significant renal dysfunction (GFR of ≤30 mL/min/1.73 m2) and implanted devices such as pacemakers and/or defibrillators Cardiac function sequence: Cine images were acquired with a steady-state, free-precession sequence in long-axis planes and contiguous short-axis slices. LGE sequence: gradient-echo sequence Contrast agent: 0.1 mmol/kg Time delay: 10 minutes LV function: Details not reported LGE diagnosis: The presence or absence of LGE was visually determined by 2 independent blinded readers and divided into 6 groups according to the LGE pattern: 1) septal subendocardial 2) lateral subendocardial 3) septal mid-wall, 4) lateral mid-wall 5) septal subepicardial 6) lateral subepicardial 7) papillary muscle pattern. techniques at a median of 16 days following the CMR. The ICD devices were programmed to detect VF and VT. Outcomes: HR for likelihood of having: ICD implantation appropriate ICD therapy life-threatening arrhythmic events in LGE+ patients compared with those that are LGE– Cho et al. () Prospective N=79 patients with Inclusion criteria: patients with ECG-proven LV systolic Scanner: Gyroscan Intera system ICD implantation: Presence or
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