years) with a history () () meta-analysis. of wheezing in () CRF from previous 12 months. () 20+ years: 1.017 Sydney. CRFs for those with All children. (1.002-1.032) per asthma. Lower respiratory 10 µg/m3 () from a Wheezing: 3.149 NOT included in symptoms include meta-analysis. (1.495-6.631) per impact assessment wheeze, chest 10 µg/m3 in the UK because tightness, shortness Australian studies () of doubts about the of breath, cough. are single site 32 children (mean transferability of the studies CRFs are age about 9.2 data and lack of UK 20+ years: 1.017 for individual years) with a history studies. (1.002-1.032) per symptoms. of wheezing in 10 µg/m3 previous 12 months. () Sydney. () CRF from analysis of five panel studies. Symptomatic adults only: wheeze, chest tightness, phlegm, shortness of breath, cough. Acute respiratory n/a n/a 1.0049 n/a n/a No CRF symptoms per 1 recommended. µg/m3 () CRF from Krupnick () et al () may be used All ages in a sensitivity Whole population. analysis. Note that Only for sensitivity CRF is statistically analysis marginally Presence of any
years) with a history of wheezing in previous 12 months. Sydney. Wheezing: 3.149 (1.495-6.631) per 10 µg/m3 () 32 children (mean age about 9.2 years) with a history of wheezing in previous 12 months. Sydney. () () () CRFs for those with asthma. NOT included in impact assessment in the UK because of doubts about the transferability of the data and lack of UK studies. () CRF from All children. Lower respiratory symptoms include wheeze, chest tightness, shortness of breath, cough. 20+ years: 1.017 (1.002-1.032) per 10 µg/m3 () () CRF from of five panel studies. Symptomatic adults only: wheeze, chest tightness, phlegm, shortness of breath, cough. meta-analysis. 20+ years: 1.017 (1.002-1.032) per 10 µg/m3 () from a meta-analysis. Australian studies are single site studies CRFs are for individual symptoms. Acute respiratory symptoms n/a n/a 1.0049 per 1 µg/m3 () () All ages Whole population. Only for sensitivity analysis Presence of any n/a n/a No CRF recommended. CRF from Krupnick et al () may be used in a sensitivity analysis. Note that CRF is statistically marginally analysis
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