Cross-sectional (cohort type accuracy False 136 85 24 study) positives (102–178) (64–111) (18–31) - ICA cut-off 70% DS - - - - - 44% - True N=190 patients Not serious Not serious Not serious Not serious None 134 392 757 High k=6 studies positives (124–140) (365–409) (705–791) ⊕⊕⊕⊕ Cross-sectional (cohort type accuracy False study) 16 48 93 negatives (10–26) (31–75) (59–145) True N=241 patients Not serious Serious Not serious Not serious None 705 465 125 Moderate negatives k=6 studies (612–774) (403–510) (108–137) ⊕⊕⊕⨀ (substantial Cross-sectional heterogeneity; (cohort type accuracy I2 = study) False 145 95 25 positives (76–238) (50–157) (13–42) - All studies - - - - - 45% - True N=486 patients Not serious Not serious Not serious Not serious None 128 383 722 High positives k=16 studies (123–132) (369–396) (697–748) ⊕⊕⊕⊕ Cross-sectional (cohort type accuracy False study) 22 67 128 negatives (18–27) (54–81) (102–153) True N=604 patients Not serious Not serious Not serious Not serious None 722 468 128 High negatives k=16 studies (689–748) (446–484) (122–132) ⊕⊕⊕⊕ False Cross-sectional positives (cohort type accuracy study) 128 82 22 (102–161) (66–104) (18–28)
False positives Cross-sectional (cohort type accuracy study) 136 85 24 (102–178) (64–111) (18–31) - ICA cut-off 70% DS - - - - - 44% - True positives False negatives N=190 patients k=6 studies Cross-sectional (cohort type accuracy study) Not serious Not serious Not serious Not serious None 134 392 757 (124–140) (365–409) (705–791) 16 48 93 (10–26) (31–75) (59–145) High ⊕⊕⊕⊕ True negatives False positives N=241 patients k=6 studies Cross-sectional (cohort type accuracy study) Not serious Serious (substantial heterogeneity; I2 = Not serious Not serious None 705 465 125 (612–774) (403–510) (108–137) 145 95 25 (76–238) (50–157) (13–42) Moderate ⊕⊕⊕⨀ - All studies - - - - - 45% - True positives False negatives N=486 patients k=16 studies Cross-sectional (cohort type accuracy study) Not serious Not serious Not serious Not serious None 128 383 722 (123–132) (369–396) (697–748) 22 67 128 (18–27) (54–81) (102–153) High ⊕⊕⊕⊕ True negatives False positives N=604 patients k=16 studies Cross-sectional (cohort type accuracy study) Not serious Not serious Not serious Not serious None 722 468 128 (689–748) (446–484) (122–132) 128 82 22 (102–161) (66–104) (18–28) High ⊕⊕⊕⊕
1237-AssessmentReport-Final.docx