CX 66 participants wireless group P2 Cohort study Hakanson et Level III-2 45 volunteers 0 complications 0 complications NS al. (2009) and 47 patients Quality: 14/26 (simultaneous CX recording) P2 Case-control study Gillies et al. Level III-2 100 27% no overall discomfort 3% no overall discomfort <0.0001 (2007) participants Quality: 13.5/26 23% discomfort score >5 45% discomfort score >5 NS catheter group CX 86% no impact on work attendance 18% no impact on work attendance <0.0001 85 participants P2 wireless group Non-randomised (but 100 controlled trial studies) Pandolfino et Level III-2 30 participants Satisfaction (the lower the better): 0.8 ± 0.1 Satisfaction (the lower the better): 1.9 ± 0.2 <0.001 Wireless group: 2 al. (2003) catheter group subjects had Quality: 11.5/26 Throat discomfort: 4/29 Throat discomfort: 22/30 <0.001 discomfort to the 29 participants CX Oesophageal discomfort: 10/29 Oesophageal discomfort: 5/30 <0.05 extent that the wireless group P3 Change daily routine: 0/29 Change daily routine: 11/30 capsule had to be Case-control Affected diet: 3% Affected diet: 47% <0.001 removed; 1 study Affected activity: 0% Affected activity: 60% <0.001 4 had moderate chest pain Disrupted sleep: 2/22 Disrupted sleep: 9/30 NS Schneider et Level III-2 55 participants Throat discomfort: 3 (3.8%) Throat discomfort: 52 (94.5%) 0.001 al. (2007) catheter group Quality: 9/26 Oesophagus discomfort: 14 (17.9%) Oesophagus discomfort: 18 (32.7%) NS 78 participants CX Reduced activities: 5 (6.4%) Reduced activities: 55 (100%) 0.0001 wireless group P3 Reliability: 75 (96.1%) Reliability: 54 (98.1%) NS Non-randomised controlled trial
CX P2 Cohort study 66 participants wireless group Hakanson et al. (2009) Level III-2 Quality: 14/26 CX P2 Case-control study 45 volunteers and 47 patients (simultaneous recording) 0 complications 0 complications NS Gillies et al. (2007) Level III-2 Quality: 13.5/26 CX P2 Non-randomised controlled trial 100 participants catheter group 85 participants wireless group (but 100 studies) 27% no overall discomfort 23% discomfort score >5 86% no impact on work attendance 3% no overall discomfort 45% discomfort score >5 18% no impact on work attendance <0.0001 NS <0.0001 Pandolfino et al. (2003) Level III-2 Quality: 11.5/26 CX P3 Case-control study 30 participants catheter group 29 participants wireless group Satisfaction (the lower the better): 0.8 ± 0.1 Throat discomfort: 4/29 Oesophageal discomfort: 10/29 Change daily routine: 0/29 Affected diet: 3% Affected activity: 0% Disrupted sleep: 2/22 Satisfaction (the lower the better): 1.9 ± 0.2 Throat discomfort: 22/30 Oesophageal discomfort: 5/30 Change daily routine: 11/30 Affected diet: 47% Affected activity: 60% Disrupted sleep: 9/30 <0.001 <0.001 <0.05 <0.001 <0.001 NS Wireless group: 2 subjects had discomfort to the extent that the capsule had to be removed; 1 4 had moderate chest pain Schneider et al. (2007) Level III-2 Quality: 9/26 CX P3 Non-randomised controlled trial 55 participants catheter group 78 participants wireless group Throat discomfort: 3 (3.8%) Oesophagus discomfort: 14 (17.9%) Reduced activities: 5 (6.4%) Reliability: 75 (96.1%) Throat discomfort: 52 (94.5%) Oesophagus discomfort: 18 (32.7%) Reduced activities: 55 (100%) Reliability: 54 (98.1%) 0.001 NS 0.0001 NS
1203-ContractedAssessmentReport-Catheter-free%20ambulatory%20pH%20test%20for%20GORD%20accessible.docx