Al-Ateah et al. Level III-2 MGIT N=239 specimens AFB (FL) 41 1 20 177 None reported () and/or L-J Xpert 58 0 4 177 Low risk of culture - AFB + NAAT 59 1 3 176 Kingdom of bias Saudi Arabia n=43 AFB +ve: Xpert 41 0 1 1 n=196 AFB –ve: Xpert 17 0 3 176 N=183 non-sputum AFB (FL) 10 1 13 159 Xpert 21 0 3 159 - AFB + NAAT 22 1 2 158 n=12 AFB +ve: Xpert 10 0 1 1 n=171 AFB –ve: Xpert 11 0 2 158 N=67 extrapulmonary AFB (FL) 6 0 11 50 Xpert 16 0 2 49 - AFB + NAAT 17 0 1 49 n=7 AFB +ve: Xpert 6 0 1 0 n=60 AFB –ve: Xpert 10 0 1 49 Malbruny et al. Level III-2 MGIT and N=180 specimens AFB (FL) 15 2 16 147 None reported () Coletsos Xpert 29 2 2 147 Low risk of slants - AFB + NAAT 29 4 2 145 France bias n=17 AFB +ve: Xpert 15 0 0 2 n=163 AFB –ve: Xpert 14 2 2 145 Malbruny et al. MGIT and N=162 non-sputum AFB (FL) 11 2 15 134 Level III-2 - () Coletsos Xpert 24 2 2 134 Low risk of slants - AFB + NAAT 24 4 2 132 France bias n=13 AFB +ve: Xpert 11 0 0 2 n=149 AFB –ve: Xpert 13 2 2 132 N=89 extrapulmonary AFB (FL) 4 1 10 74 Xpert 12 2 2 73 - AFB + NAAT 12 3 2 72 n=5 AFB +ve: Xpert 4 0 0 1 n=84 AFB –ve: Xpert 8 2 2 72 Solid L-J N=160 HIV+ sputum or HIV+ AFB (ZN) 8 2 4 146 Repeated Xpert Balcells et al. () Level III-2
Al-Ateah et al. () Kingdom of Saudi Arabia Level III-2 Low risk of bias MGIT and/or L-J culture N=239 specimens - n=43 n=196 N=183 non-sputum - n=12 n=171 N=67 extrapulmonary - n=7 n=60 AFB (FL) Xpert AFB + NAAT AFB +ve: Xpert AFB –ve: Xpert AFB (FL) Xpert AFB + NAAT AFB +ve: Xpert AFB –ve: Xpert AFB (FL) Xpert AFB + NAAT AFB +ve: Xpert AFB –ve: Xpert 41 58 59 41 17 10 21 22 10 11 6 16 17 6 10 1 0 1 0 0 1 0 1 0 0 0 0 0 0 0 20 4 3 1 3 13 3 2 1 2 11 2 1 1 1 177 177 176 1 176 159 159 158 1 158 50 49 49 0 49 None reported Malbruny et al. () France Level III-2 Low risk of bias MGIT and Coletsos slants N=180 specimens - n=17 n=163 AFB (FL) Xpert AFB + NAAT AFB +ve: Xpert AFB –ve: Xpert 15 29 29 15 14 2 2 4 0 2 16 2 2 0 2 147 147 145 2 145 None reported Malbruny et al. () France Level III-2 Low risk of bias MGIT and Coletsos slants N=162 non-sputum - n=13 n=149 N=89 extrapulmonary - n=5 n=84 AFB (FL) Xpert AFB + NAAT AFB +ve: Xpert AFB –ve: Xpert AFB (FL) Xpert AFB + NAAT AFB +ve: Xpert AFB –ve: Xpert 11 24 24 11 13 4 12 12 4 8 2 2 4 0 2 1 2 3 0 2 15 2 2 0 2 10 2 2 0 2 134 134 132 2 132 74 73 72 1 72 - Balcells et al. () Level III-2 Solid L-J N=160 HIV+ sputum or HIV+ AFB (ZN) 8 2 4 146 Repeated Xpert
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