Principi Computer Unspecified. States that the States that both LI and Much higher percentage Apparently free of calculations et al. generated. patients and intensity staining were withdrawal in intervention selective outcome provided but (2013)24 investigators calculated by two than control group. 7 out of reporting - all stated required sample were blinded to independent observers in 30 patients withdrew from outcomes reported. size not met. assignment a blinded fashion without the intervention group (4 without providing any further withdrew consent before providing any information. T60 colonoscopy and 3 were further lost to T60 colonoscopy). 3 information. out of 30 patients withdrew from the control group (3 withdrew consent before T60 colonoscopy). Shimizu Not described. Unspecified. No blinding of States that endoscopists 8 patients were lost to Apparently free of calculations et al. participants were blinded to the study follow up in intervention selective outcome not provided. (2008)22 because the group but no further arm only as they could not reporting - all stated control group information provided. be reached from the day outcomes reported. received no after the initiation of the placebo trial. No intention to treat supplement. analysis included. Author refers to it in the discussion and states that the results were insignificant.
Principi et al. (2013)24 Computer generated. Unspecified. States that the patients and investigators were blinded to assignment without providing any further information. States that both LI and intensity staining were calculated by two independent observers in a blinded fashion without providing any further information. Much higher percentage withdrawal in intervention than control group. 7 out of 30 patients withdrew from the intervention group (4 withdrew consent before T60 colonoscopy and 3 were lost to T60 colonoscopy). 3 out of 30 patients withdrew from the control group (3 withdrew consent before T60 colonoscopy). Apparently free of selective outcome reporting - all stated outcomes reported. calculations provided but required sample size not met. Shimizu et al. (2008)22 Not described. Unspecified. No blinding of participants because the control group received no placebo supplement. States that endoscopists were blinded to the study group but no further information provided. 8 patients were lost to follow up in intervention arm only as they could not be reached from the day after the initiation of the trial. No intention to treat analysis included. Author refers to it in the discussion and states that the results were insignificant. Apparently free of selective outcome reporting - all stated outcomes reported. calculations not provided.
Paper_systematic_review_diet_int_CRC_survivors_with_amendments_FINAL_CLEAN_VERSION2_incl_tables.docx