Special Precautions for Animal Work with Chemicals of High Chronic Toxicity: See Appendix E of this manual for definition and discussion of the meanings of chronic and acute toxicity. For large scale studies, special facilities with restricted access are preferable. When possible, administer the substance by injection or lavage instead of in diet. If administration is in the diet, use a caging system under negative pressure or under laminar air flow directed through HEPA filters prior to discharge. Devise procedures which minimize formation and dispersal of contaminated aerosols, including those from food, urine, and feces (e.g., use HEPA filtered vacuum equipment for cleaning; moisten contaminated bedding before removal from the cage; mix diets in closed containers in a hood). When working in the animal room, wear plastic or rubber gloves, fully buttoned laboratory coat or jumpsuit and, if needed because of incomplete suppression of aerosols, other apparel and equipment (shoe and head coverings, respirator). Dispose of contaminated animal tissues and excreta using approved methods. BIOLOGICAL HAZARDS Policies and procedures pertaining to biological safety are contained in the "Purdue University Biological Safety Manual." Contact the REM Environmental Health Section for a copy of this manual. RADIOACTIVE MATERIAL HAZARDS Use of radioactive materials at is strictly controlled. The policies and procedures for handling radioactive materials are contained in the "Purdue University Radiation Safety Manual." Contact the REM Radiation Safety Section if you are planning on using radioactive materials. IONIZING AND NON-IONIZING RADIATION HAZARDS Laser safety, x-ray safety, and all concerns pertaining to the hazards of ionizing and radiation are the purview of the REM Radiation Safety Section. Contact them at 47969 for information on training schedules as well as for printed training materials and policies and procedures documents TRANSPORTATION OF HAZARDOUS MATERIALS TRANSPORTATION OVER THE ROAD Any container of hazardous material transported on a road accessible to or used by the public is subject to the regulation by the U.S. Department of Transportation (DOT). DOT
Special Precautions for Animal Work with Chemicals of High Chronic Toxicity: See Appendix E of this manual for definition and discussion of the meanings of chronic and acute toxicity. For large scale studies, special facilities with restricted access are preferable. When possible, administer the substance by injection or lavage instead of in diet. If administration is in the diet, use a caging system under negative pressure or under laminar air flow directed through HEPA filters prior to discharge. Devise procedures which minimize formation and dispersal of contaminated aerosols, including those from food, urine, and feces (e.g., use HEPA filtered vacuum equipment for cleaning; moisten contaminated bedding before removal from the cage; mix diets in closed containers in a hood). When working in the animal room, wear plastic or rubber gloves, fully buttoned laboratory coat or jumpsuit and, if needed because of incomplete suppression of aerosols, other apparel and equipment (shoe and head coverings, respirator). Dispose of contaminated animal tissues and excreta using approved methods. BIOLOGICAL HAZARDS Policies and procedures pertaining to biological safety are contained in the "Purdue University Biological Safety Manual." Contact the REM Environmental Health Section for a copy of this manual. RADIOACTIVE MATERIAL HAZARDS Use of radioactive materials at is strictly controlled. The policies and procedures for handling radioactive materials are contained in the "Purdue University Radiation Safety Manual." Contact the REM Radiation Safety Section if you are planning on using radioactive materials. IONIZING AND NON-IONIZING RADIATION HAZARDS Laser safety, x-ray safety, and all concerns pertaining to the hazards of ionizing and radiation are the purview of the REM Radiation Safety Section. Contact them at 47969 for information on training schedules as well as for printed training materials and policies and procedures documents TRANSPORTATION OF HAZARDOUS MATERIALS TRANSPORTATION OVER THE ROAD Any container of hazardous material transported on a road accessible to or used by the public is subject to the regulation by the U.S. Department of Transportation (DOT). DOT
Evans2014CHP.docx