TOF analyzer/High resolution mass analyzer with ion source and ion reflectron with increased mass resolution & accuracy. It should have positive and negative ion modes. The instrument should be capable of performing MS Scanning, MS/MS product ion scanning and simultaneous MS and MS/MS scanning. The system should capable to do both Data dependent and Data Independent analysis. The system should be capable of performing Qualitative and relative (label free) Quantitative analysis with the highest sensitivity, accuracy, precision and reproducibility. It should also be capable of performing unlabelled quantitation across the mass range like in SWATH/DIA/MSeetc. Desolvation temperature should be > 400oC or better System should be capable of doing intact mass analysis Mass Range of Quadruple Mass Range should be up to 2000 m/z or better for singly Quadrapole: charged ions. Mass Range of TOF Mass Range of the analyzer must be from 50 to 40,000 m/z or better. high resolution In case of orbitrap 6000 m/z maintaining high resolution in the same mode Mass System (TOF/Orbitrap system): Acquisition 30 spectra per second in case of TOF and 15 spectra or better per second in Rate: case of Orbitrap Technology over the entire mass range Resolution: >35,000 FWHM or better in broad range, in case of orbitrap resolution >100,000 FWHM or better. Mass 1ppm internal calibrate and 3 ppm external calibrate Accuracy: The instrument should be capable of internal reference mass correction by Reference Mass infusing calibrant on the run Introduction: Switching time: +/- ve switching time should be less than 2 sec Sensitivity: <300 fg standard signal/noise ratio, 100:1 S/ N ratio with reserpine. Dynamic Range: 4 order of dynamic range or better Gas generator Imported PEAK® gas generator with built-in compressor capable of cum providing all the gases at the required purity pressure and flow rate for compressor: the Mass Spectrometer must be quoted.
TOF analyzer/High resolution mass analyzer with ion source and ion reflectron with increased mass resolution & accuracy. It should have positive and negative ion modes. The instrument should be capable of performing MS Scanning, MS/MS product ion scanning and simultaneous MS and MS/MS scanning. The system should capable to do both Data dependent and Data Independent analysis. The system should be capable of performing Qualitative and relative (label free) Quantitative analysis with the highest sensitivity, accuracy, precision and reproducibility. It should also be capable of performing unlabelled quantitation across the mass range like in SWATH/DIA/MSeetc. Desolvation temperature should be > 400oC or better System should be capable of doing intact mass analysis Mass Range of Quadrapole: Mass Range of high resolution Mass System (TOF/Orbitrap system): Acquisition Rate: Resolution: Mass Accuracy: Reference Mass Introduction: Switching time: Sensitivity: Dynamic Range: Quadruple Mass Range should be up to 2000 m/z or better for singly charged ions. TOF Mass Range of the analyzer must be from 50 to 40,000 m/z or better. In case of orbitrap 6000 m/z maintaining high resolution in the same mode 30 spectra per second in case of TOF and 15 spectra or better per second in case of Orbitrap Technology over the entire mass range >35,000 FWHM or better in broad range, in case of orbitrap resolution >100,000 FWHM or better. 1ppm internal calibrate and 3 ppm external calibrate The instrument should be capable of internal reference mass correction by infusing calibrant on the run +/- ve switching time should be less than 2 sec <300 fg standard signal/noise ratio, 100:1 S/ N ratio with reserpine. 4 order of dynamic range or better Gas generator cum compressor: Imported PEAK® gas generator with built-in compressor capable of providing all the gases at the required purity pressure and flow rate for the Mass Spectrometer must be quoted.
EXPRESSION%20OF%20INTEREST%20FOR%20HI%20(2).docx