a diabetes although 2009 and April 2010. disease, history of gestational intervention conduct of N=3,921, age diabetes). program, from study has low years. No further Excluded n=15 patients but no primary care level of bias. details reported. reasons given. family practices Applicable to in England. Australian setting as culturally similar and general practice setting. Appropriate cut-offs. Santos-Rey () Level III-2 Low risk of Consecutive patients Patients with two or more risk factors: Not Not FPG: Not ROC Seville, Spain bias in study aged 18–70 years obesity, dyslipidaemia, hypertension, reported reported 5.6 mmol/L≥ reported analysis for Study of design. with at least two risk previous IGT or family history of FPG IGT patients from a population factors recruited diabetes) were included. Patients <7.0 mmol/L; cardiovascular applicable to between March 2005 aged less than 18 years or 70 years risk clinic in a 7.8 mmol/L≥ population in and Nov 2008 from a or older were excluded. Only patients Spanish 2hPG question, cardiovascular risk with FPG <7.0 mmol/L had OGT tests Hospital; study <11.1 mmol/L although clinic. N=713, mean and are included in ROC analysis. primarily Spanish. age 51 ± 12 years, concerned with 50% male, 98% diagnosing IGT. Appropriate Caucasian. cut-offs. Snehalatha () Level III-2 Risk of bias Patients recruited Patients had no known history of Not Not Not reported FPG ROC Chennai, unclear due to from diabetes clinic diabetes. No other criteria described. reported reported >125 analysis Study of India inadequate between July and Dec patients who description of 1998, but recruitment underwent 2hPG population. not described. diabetes testing ≥200 Questionable N=1,261 participants, in a hospital applicability to mean age diabetes clinic Australia as 40 ± 12 years, 67% in India. Indian male. Many had population. strong family history Appropriate of diabetes or other cut-offs. risk factors, but not described.
a diabetes intervention program, from primary care family practices in England. although conduct of study has low level of bias. Applicable to Australian setting as culturally similar and general practice setting. Appropriate cut-offs. 2009 and April 2010. N=3,921, age years. No further details reported. disease, history of gestational diabetes). Excluded n=15 patients but no reasons given. Santos-Rey () Seville, Spain Level III-2 Study of patients from a cardiovascular risk clinic in a Spanish Hospital; study primarily concerned with diagnosing IGT. Low risk of bias in study design. population applicable to population in question, although Spanish. Appropriate cut-offs. Consecutive patients aged 18–70 years with at least two risk factors recruited between March 2005 and Nov 2008 from a cardiovascular risk clinic. N=713, mean age 51 ± 12 years, 50% male, 98% Caucasian. Patients with two or more risk factors: obesity, dyslipidaemia, hypertension, previous IGT or family history of diabetes) were included. Patients aged less than 18 years or 70 years or older were excluded. Only patients with FPG <7.0 mmol/L had OGT tests and are included in ROC analysis. Not reported Not reported FPG: 5.6 mmol/L≥ FPG <7.0 mmol/L; 7.8 mmol/L≥ 2hPG <11.1 mmol/L Not reported ROC analysis for IGT Snehalatha () Chennai, India Level III-2 Study of patients who underwent diabetes testing in a hospital diabetes clinic in India. Risk of bias unclear due to inadequate description of population. Questionable applicability to Australia as Indian population. Appropriate cut-offs. Patients recruited from diabetes clinic between July and Dec 1998, but recruitment not described. N=1,261 participants, mean age 40 ± 12 years, 67% male. Many had strong family history of diabetes or other risk factors, but not described. Patients had no known history of diabetes. No other criteria described. Not reported Not reported Not reported FPG >125 2hPG ≥200 ROC analysis
1267-FinalContractedAssessmentReport-accessible.DOCX