interventions for Japanese 2 hours after a meal); 110 mg/dL≥ diabetes population. FPG (3) 110 mg/dL≤ CPG <140 mg/dL prevention; <126 mg/dL; Cut-offs (more than 2 hours after a meal); subjects 2hPG different to (4) IGT by 75 g OGT at original recruited to <140 mg/dL current screen for recruitment to the RCT. have OGT test. criteria. Hajat () Level III-2 Risk of bias N=1,028 people Not reported. Unknown how many Not Not Not reported FPG ROC unclear as 18 years of age or were recalled for OGT test and how reported reported ≥7.0 analysis Abu Dhabi, Patients only patients older included, but not many actually had tests. United Arab recruited from with HbA1c described. Emirates 2hPG >6.1%, ≥11.1 random screening glucose program in ≥11.1 mmol/L community or missing setting in Abu data recalled Dhabi; after for OGT test. initial screen, patients with Middle possible Eastern diabetes population, so recalled for some further testing concerns including OGT. about applicability. Appropriate cut-offs. Hu () Level III-2 Low risk of N=2,298 participants, Participants had at least one of: Not Not IGT: FPG ROC Shanghai, bias in study 42% male, mean age family history of diabetes, history of reported reported ≥7.0 analysis Participants with FPG China design. Some 52.4 years (SD 13.3). gestational diabetes, obesity or at least one risk <7.0 mmol/L; concerns with history of IGT. Excluded subjects with factor for 7.8 mmol/L≥ or 2hPG applicability to previously diagnosed diabetes, diabetes were 2hPG ≥11.1 Australian receiving medication for diabetes or identified from <11.1 mmol/L; setting as who were pregnant. medical IFG: Chinese examination 6.1 mmol/L≥ population. database and FPG invited to attend Cut-offs <7.0 mmol/L; for diabetes appropriate. 2hPG
interventions for diabetes prevention; subjects recruited to have OGT test. Japanese population. Cut-offs different to current criteria. 2 hours after a meal); (3) 110 mg/dL≤ CPG <140 mg/dL (more than 2 hours after a meal); (4) IGT by 75 g OGT at original screen for recruitment to the RCT. 110 mg/dL≥ FPG <126 mg/dL; 2hPG <140 mg/dL Hajat () Abu Dhabi, United Arab Emirates Level III-2 Patients recruited from screening program in community setting in Abu Dhabi; after initial screen, patients with possible diabetes recalled for further testing including OGT. Risk of bias unclear as only patients with HbA1c >6.1%, random glucose ≥11.1 mmol/L or missing data recalled for OGT test. Middle Eastern population, so some concerns about applicability. Appropriate cut-offs. N=1,028 people 18 years of age or older included, but not described. Not reported. Unknown how many were recalled for OGT test and how many actually had tests. Not reported Not reported Not reported FPG ≥7.0 2hPG ≥11.1 ROC analysis Hu () Shanghai, China Level III-2 Participants with at least one risk factor for diabetes were identified from medical examination database and invited to attend for diabetes Low risk of bias in study design. Some concerns with applicability to Australian setting as Chinese population. Cut-offs appropriate. N=2,298 participants, 42% male, mean age 52.4 years (SD 13.3). Participants had at least one of: family history of diabetes, history of gestational diabetes, obesity or history of IGT. Excluded subjects with previously diagnosed diabetes, receiving medication for diabetes or who were pregnant. Not reported Not reported IGT: FPG <7.0 mmol/L; 7.8 mmol/L≥ 2hPG <11.1 mmol/L; IFG: 6.1 mmol/L≥ FPG <7.0 mmol/L; 2hPG FPG ≥7.0 or 2hPG ≥11.1 ROC analysis
1267-FinalContractedAssessmentReport-accessible.DOCX