Table 3 Economic model: Net costs and QALYs of PEd compared with TAU Net cost, Net QALY, Net cost Probability PEd cost effective (95% CI) per QALY, £ (95% CI) WTPT = £20K WTPT = £25K WTPT = £30K per QALY per QALY per QALY Probability of relapse higher in TAU than PEd1 15% higher 97 0.010 9700 0.48 0.50 0.51 (-0.266; 0.269) (-6613; 4890) 20% higher 18 0.014 1286 0.50 0.51 0.52 (-0.277; 0.290) (-7404; 5065) 25% higher -60 0.017 PEd dominates 0.51 0.52 0.53 (-0.292; 0.312) (-8142; 5136) Probability and time to relapse2 Probability 10% higher, £103 0.010 £10,300 0.48 0.49 0.50 (-0.233; 0.240) time 10% lower (-5912; 4320) Probability 15% higher, -£18 0.015 PEd dominates 0.50 0.51 0.52 (-0.233; 0.263) time 15% lower (-6710; 4123) Probability 20% higher, £-141 0.020 PEd dominates 0.52 0.53 0.54 (-0.239; 0.288) time 20% (-7558; 4135) 1probability of relapse in PEd = 0.58 (95% CI 0.50-0.66) 2mean time (weeks) to relapse in PEd = 29.63 (95% CI 24.21-35.06) WTPT = willingness to pay threshold
Table 3 Economic model: Net costs and QALYs of PEd compared with TAU Net cost, (95% CI) Net QALY, (95% CI) Net cost per QALY, £ Probability PEd cost effective WTPT = £20K per QALY WTPT = £25K per QALY WTPT = £30K per QALY Probability of relapse higher in TAU than PEd1 15% higher 97 (-6613; 4890) 0.010 (-0.266; 0.269) 9700 0.48 0.50 0.51 20% higher 18 (-7404; 5065) 0.014 (-0.277; 0.290) 1286 0.50 0.51 0.52 25% higher -60 (-8142; 5136) 0.017 (-0.292; 0.312) PEd dominates 0.51 0.52 0.53 Probability and time to relapse2 Probability 10% higher, time 10% lower £103 (-5912; 4320) 0.010 (-0.233; 0.240) £10,300 0.48 0.49 0.50 Probability 15% higher, time 15% lower -£18 (-6710; 4123) 0.015 (-0.233; 0.263) PEd dominates 0.50 0.51 0.52 Probability 20% higher, time 20% £-141 (-7558; 4135) 0.020 (-0.239; 0.288) PEd dominates 0.52 0.53 0.54 1probability of relapse in PEd = 0.58 (95% CI 0.50-0.66) 2mean time (weeks) to relapse in PEd = 29.63 (95% CI 24.21-35.06) WTPT = willingness to pay threshold
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