family history 53% Klem et al. () Level IV N=100 consecutive patients with Exclusion criteria: Adenosine SP-CMR + LGE suspected CAD scheduled for ICA USA A case series with either Patients with known CAD including those with prior MI or post-test or Mean age: 58 ± 11.5 years revascularisation procedures; and contraindications to CMR (e.g. outcomes n=47/92 women (51%) pacemaker) or adenosine (e.g. high-grade AV-block) Low risk of bias Angina according to Rose chest pain (IHE 8/12) questionnaire: 34% CAD risk factors: hypertension 64% hypercholesterolaemia 54% smoker 39% diabetes 23% family history 52% Korosoglou et Level IV: N=1,493 consecutive patients with Exclusion criteria: Dobutamine SP-CMR, using a al. () suspected or known CAD underwent standard protocol in a 1.5-T A case series with either Non-sinus rhythm; unstable angina; severe arterial hypertension dobutamine SP-CMR magnetic resonance scanner Germany post-test or (200/120 mm Hg), moderate or severe valvular disease; and general contraindications to CMR (e.g. implanted pacemakers or outcomes Mean age: 65 ± 13 years defibrillators) Some risk of bias n=383 women (26%) (IHE 7.5/12) CAD risk factors: hypertension 71% hyperlipidaemia 53% smoker 18% diabetes 19% family history 22%
family history 53% Klem et al. () USA Level IV A case series with either post-test or outcomes Low risk of bias (IHE 8/12) N=100 consecutive patients with suspected CAD scheduled for ICA Mean age: 58 ± 11.5 years n=47/92 women (51%) Angina according to Rose chest pain questionnaire: 34% CAD risk factors: hypertension 64% hypercholesterolaemia 54% smoker 39% diabetes 23% family history 52% Exclusion criteria: Patients with known CAD including those with prior MI or revascularisation procedures; and contraindications to CMR (e.g. pacemaker) or adenosine (e.g. high-grade AV-block) Adenosine SP-CMR + LGE Korosoglou et al. () Germany Level IV: A case series with either post-test or outcomes Some risk of bias (IHE 7.5/12) N=1,493 consecutive patients with suspected or known CAD underwent dobutamine SP-CMR Mean age: 65 ± 13 years n=383 women (26%) CAD risk factors: hypertension 71% hyperlipidaemia 53% smoker 18% diabetes 19% family history 22% Exclusion criteria: Non-sinus rhythm; unstable angina; severe arterial hypertension (200/120 mm Hg), moderate or severe valvular disease; and general contraindications to CMR (e.g. implanted pacemakers or defibrillators) Dobutamine SP-CMR, using a standard protocol in a 1.5-T magnetic resonance scanner
1237-AssessmentReport-Final.docx