suggested within Austrian product also includes the literature to be nitrogen as an excipient – the impact unclear “safest”. medac Benzyl alcohol, Citric acid, Similar content: UK product contains benzyl alcohol GmbH(Eposin) anhydrous, Ethanol, Macrogol Austrian product also includes Other excipients may be different 300, Polysorbate 80 Same content nitrogen as an excipient impact concentrations – Currently used in unclear UK practice. Accord Healthcare Benzyl alcohol, Citric acid, Similar content except: UK product contains benzyl alcohol Limited anhydrous, Ethanol, Austrian product also includes Other excipients may be different Same content anhydrous, Macrogol 300, nitrogen impact unclear concentrations – Polysorbate 80 Actavis UK Ltd Citric acid, anhydrous, Similar content except: Similar content except: Similar content except: Ethanol, anhydrous, Macrogol UK product does not contain UK product does not contain benzyl UK product utilises macrogol 400 400, Polysorbate 80 benzyl alcohol potentially alcohol potentially beneficial instead of macrogol 300 impact – – – beneficial UK product utilises macrogol 400 unclear UK product utilises macrogol instead of macrogol 300 impact – 400 instead of macrogol 300 unclear – impact unclear Austrian product also includes nitrogen impact unclear – Cipla (EU) Limited Benzyl alcohol, Citric acid, Similar content: UK product contains benzyl alcohol anhydrous, Ethanol, Macrogol Austrian product also includes Other excipients may be different Same content 300, Polysorbate 80 nitrogen as an excipient impact concentrations – unclear Fresenius Kabi Benzyl alcohol, Citric acid, Similar content: UK product contains benzyl alcohol Oncology Plc. Ethanol Anhydrous, Macrogol Austrian product also includes Other excipients may be different Same content 300, Polysorbate 80 nitrogen as an excipient impact concentrations – unclear
suggested within the literature to be the “safest”. Austrian product also includes nitrogen as an excipient – impact unclear medac GmbH(Eposin) Currently used in UK practice. Benzyl alcohol, Citric acid, anhydrous, Ethanol, Macrogol 300, Polysorbate 80 Same content Similar content: Austrian product also includes nitrogen as an excipient – impact unclear UK product contains benzyl alcohol Other excipients may be different concentrations Accord Healthcare Limited Benzyl alcohol, Citric acid, anhydrous, Ethanol, anhydrous, Macrogol 300, Polysorbate 80 Same content Similar content except: Austrian product also includes nitrogen – impact unclear UK product contains benzyl alcohol Other excipients may be different concentrations Actavis UK Ltd Citric acid, anhydrous, Ethanol, anhydrous, Macrogol 400, Polysorbate 80 Similar content except: UK product does not contain benzyl alcohol – potentially beneficial UK product utilises macrogol 400 instead of macrogol 300 – impact unclear Similar content except: UK product does not contain benzyl alcohol – potentially beneficial UK product utilises macrogol 400 instead of macrogol 300 – impact unclear Austrian product also includes nitrogen – impact unclear Similar content except: UK product utilises macrogol 400 instead of macrogol 300 – impact unclear Cipla (EU) Limited Benzyl alcohol, Citric acid, anhydrous, Ethanol, Macrogol 300, Polysorbate 80 Same content Similar content: Austrian product also includes nitrogen as an excipient – impact unclear UK product contains benzyl alcohol Other excipients may be different concentrations Fresenius Kabi Oncology Plc. Benzyl alcohol, Citric acid, Ethanol Anhydrous, Macrogol 300, Polysorbate 80 Same content Similar content: Austrian product also includes nitrogen as an excipient – impact unclear UK product contains benzyl alcohol Other excipients may be different concentrations
Etoposide-Intrathecal-Use-final.docx