Foreign-body Pandolfino et al. Cohort study 44 controls (13 males, 31 females, Inclusion: Index test: sensation () aged 23–53 years) Not stated System: Bravo™ wireless capsule system Chest pain Northwestern Level: III-2 Insertion: transorally Throat discomfort University 41 patients (26 males, 15 females, Quality: 11.5/26 Exclusion: Placement: 6 cm above the SCJ Late detachment Feinberg School aged 32–72 years) of Medicine, Oesophageal CX Controls: abdominal symptoms, use of Chicago, Illinois, discomfort antacids or antisecretory medication, P3 Comparator: USA Eating and drinking abnormal endoscopy System: not stated (catheter-based) Activity Patients: history of surgical manipulation Insertion: transnasally Sleep patterns of the upper GI tract, history of bleeding diathesis or coagulopathy, stroke or Placement: not stated transient ischemic attack in the past Duration: 24 hours 6 months, significant medical illness, oesophageal varices Chest discomfort Pandolfino et al. 10 normal control subjects (7 males Case series Inclusion: Index test: Foreign-body () and 3 females, aged 21–53 years) Controls: no history of heartburn, reflux, System: Bravo™ wireless capsule system sensation Division of chest pain or atypical symptoms Level: IV Insertion: transorally Gastroenterology, 10 patients with GORD (6 males and Patients: oesophagitis (3) or an abnormal Quality: Q2 Placement: 1 cm proximal to SCJ Department of 4 females, aged 20–54 years) 24-hour oesophageal pH study prior to Medicine, CX (no Duration: 24 hours this study Feinberg School comparator) Comparator: NA Exclusion: of Medicine, P3 Northwestern History of surgical manipulation of the University, upper GI tract, anticoagulation therapy, Chicago, Illinois, significant medical disease USA Controls: abdominal symptoms, use of antacids, abnormal upper endoscopy
Pandolfino et al. () Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA Cohort study Level: III-2 Quality: 11.5/26 CX P3 44 controls (13 males, 31 females, aged 23–53 years) 41 patients (26 males, 15 females, aged 32–72 years) Inclusion: Not stated Exclusion: Controls: abdominal symptoms, use of antacids or antisecretory medication, abnormal endoscopy Patients: history of surgical manipulation of the upper GI tract, history of bleeding diathesis or coagulopathy, stroke or transient ischemic attack in the past 6 months, significant medical illness, oesophageal varices Index test: System: Bravo™ wireless capsule system Insertion: transorally Placement: 6 cm above the SCJ Comparator: System: not stated (catheter-based) Insertion: transnasally Placement: not stated Duration: 24 hours Foreign-body sensation Chest pain Throat discomfort Late detachment Oesophageal discomfort Eating and drinking Activity Sleep patterns Pandolfino et al. () Division of Gastroenterology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA Case series Level: IV Quality: Q2 CX (no comparator) P3 10 normal control subjects (7 males and 3 females, aged 21–53 years) 10 patients with GORD (6 males and 4 females, aged 20–54 years) Inclusion: Controls: no history of heartburn, reflux, chest pain or atypical symptoms Patients: oesophagitis (3) or an abnormal 24-hour oesophageal pH study prior to this study Exclusion: History of surgical manipulation of the upper GI tract, anticoagulation therapy, significant medical disease Controls: abdominal symptoms, use of antacids, abnormal upper endoscopy Index test: System: Bravo™ wireless capsule system Insertion: transorally Placement: 1 cm proximal to SCJ Duration: 24 hours Comparator: NA Chest discomfort Foreign-body sensation
1203-ContractedAssessmentReport-Catheter-free%20ambulatory%20pH%20test%20for%20GORD%20accessible.docx