hypertension 68% hypercholesterolaemia 70% smoker 57% diabetes 14% Plein et al. () Level IV N=92 patients who were suspected of Exclusion criteria: Adenosine SP-CMR having or known to have CAD and were UK A case series with either Obstructive airway disease; cardiac arrhythmias; and scheduled to undergo conventional ICA post-test or contraindications to cardiac CMR owing to clinical referral outcomes Mean age, 58 ± 11 years Moderate risk of bias n=24 women (26%) (IHE 6.5/12) Previous MI 21% CAD risk factors: hypertension 33% hypercholesterolaemia 59% smoker 38% diabetes 9% family history 43% Regenfus et Level IV N=427 CA segments from 61 patients Exclusion criteria: Nitroglycerin SP-CMR al. () referred for diagnostic ICA due to clinically A case series with either Patients with arrhythmias; in unstable clinical condition; or with suspected CAD Germany post-test or contraindications to CMR imaging (e. g. cardiac pacemakers, other outcomes Mean age, 63 ± 6 years ferromagnetic implants or claustrophobia) n=9 women (15%) Moderate risk of bias (IHE 6/12) Sakuma et al. Level IV N=40 patients with suspected CAD Inclusion criteria: Dipyridamole SP-CMR + LGE () A case series with either Mean age, 64.6 ± 9.0 years Underwent stress first-pass contrast-enhanced CMR, stress Japan post-test or n=12 women (30%) thallium-201 SPECT and ICA within 4 weeks outcomes Exclusion criteria: Moderate risk of bias Previous MI; abnormal Q-wave on ECG; chest pain at rest; (IHE 5/12) abnormal myocardial wall motion; severe arrhythmia; and coronary
hypertension 68% hypercholesterolaemia 70% smoker 57% diabetes 14% Plein et al. () UK Level IV A case series with either post-test or outcomes Moderate risk of bias (IHE 6.5/12) N=92 patients who were suspected of having or known to have CAD and were scheduled to undergo conventional ICA owing to clinical referral Mean age, 58 ± 11 years n=24 women (26%) Previous MI 21% CAD risk factors: hypertension 33% hypercholesterolaemia 59% smoker 38% diabetes 9% family history 43% Exclusion criteria: Obstructive airway disease; cardiac arrhythmias; and contraindications to cardiac CMR Adenosine SP-CMR Regenfus et al. () Germany Level IV A case series with either post-test or outcomes Moderate risk of bias (IHE 6/12) N=427 CA segments from 61 patients referred for diagnostic ICA due to clinically suspected CAD Mean age, 63 ± 6 years n=9 women (15%) Exclusion criteria: Patients with arrhythmias; in unstable clinical condition; or with contraindications to CMR imaging (e. g. cardiac pacemakers, other ferromagnetic implants or claustrophobia) Nitroglycerin SP-CMR Sakuma et al. () Japan Level IV A case series with either post-test or outcomes Moderate risk of bias (IHE 5/12) N=40 patients with suspected CAD Mean age, 64.6 ± 9.0 years n=12 women (30%) Inclusion criteria: Underwent stress first-pass contrast-enhanced CMR, stress thallium-201 SPECT and ICA within 4 weeks Exclusion criteria: Previous MI; abnormal Q-wave on ECG; chest pain at rest; abnormal myocardial wall motion; severe arrhythmia; and coronary Dipyridamole SP-CMR + LGE
1237-AssessmentReport-Final.docx