(IHE 8/12) Mean age: 62 ± 8 years disease; pregnancy; atrial fibrillation; renal insufficiency (creatinine n=35/103 women (34%) clearance ≤60 mL/minute); and standard contraindications to CMR, adenosine and gadolinium 66% had intermediate or high PTP for CAD using the modified score CAD risk factors: hypertension 73% hypercholesterolaemia 80% smoker 14% diabetes 39% family history 20% Bruder et al. () Level IV: N=27,301 consecutive patients Exclusion criteria: CMR used according to the undergoing CMR according to the ACCF/ACR/SCCT/ Europe A case series with either Not reported ACCF/ACR/SCCT/SCMR/ASNC/NASCI/ SCMR/ASNC/NASCI/ SCAI/SIR post-test or SCAI/SIR 2006 consensus 2006 consensus outcomes appropriateness criteria for CMR imaging appropriateness criteria Low risk of bias from 57 participating centres (IHE 8/12) Mean age: 60 years (range 47–70) Women: 35% Primary indication of suspected CAD or ischaemia in known CAD: 34.2% Bunce et al. () Level IV: N=35 consecutive patients undergoing Exclusion criteria: Adenosine SP-CMR diagnostic ICA for the investigation of A case series with either An inability or unwillingness to give informed consent; unstable UK angina post-test or angina or recent MI; the presence of an implanted permanent outcomes Mean age: 56 ± 12 years (range 34–81) pacemaker, defibrillator or intracranial clips; significant n=8/35 women (23%) claustrophobia; bronchial asthma; or previous CABG surgery Moderate risk of bias Mean LVEF: 61 ± 12% (IHE 6.5/12) CAD risk factors: hypertension 34% smoker 46%
(IHE 8/12) Mean age: 62 ± 8 years n=35/103 women (34%) 66% had intermediate or high PTP for CAD using the modified score CAD risk factors: hypertension 73% hypercholesterolaemia 80% smoker 14% diabetes 39% family history 20% disease; pregnancy; atrial fibrillation; renal insufficiency (creatinine clearance ≤60 mL/minute); and standard contraindications to CMR, adenosine and gadolinium Bruder et al. () Europe Level IV: A case series with either post-test or outcomes Low risk of bias (IHE 8/12) N=27,301 consecutive patients undergoing CMR according to the ACCF/ACR/SCCT/SCMR/ASNC/NASCI/ SCAI/SIR 2006 consensus appropriateness criteria for CMR imaging from 57 participating centres Mean age: 60 years (range 47–70) Women: 35% Primary indication of suspected CAD or ischaemia in known CAD: 34.2% Exclusion criteria: Not reported CMR used according to the ACCF/ACR/SCCT/ SCMR/ASNC/NASCI/ SCAI/SIR 2006 consensus appropriateness criteria Bunce et al. () UK Level IV: A case series with either post-test or outcomes Moderate risk of bias (IHE 6.5/12) N=35 consecutive patients undergoing diagnostic ICA for the investigation of angina Mean age: 56 ± 12 years (range 34–81) n=8/35 women (23%) Mean LVEF: 61 ± 12% CAD risk factors: hypertension 34% smoker 46% Exclusion criteria: An inability or unwillingness to give informed consent; unstable angina or recent MI; the presence of an implanted permanent pacemaker, defibrillator or intracranial clips; significant claustrophobia; bronchial asthma; or previous CABG surgery Adenosine SP-CMR
1237-AssessmentReport-Final.docx