with MPI without addressing the diagnostic accuracy of coronary artery stenosis or occlusion, and studies including patients treated with coronary stents or bypass grafts Beanlands et al. () 18% To define Canadian Search period: Multidetector CTCA ICA: DS cut-off (2/11) recommendations for the at 50% or above Canada Up to June 2005 16-slice: k=19 clinical use of advanced Poor imaging modalities Databases searched: 64slice: k=4 quality with a high risk Medline, EMBASE, Cochrane library, and other evidence-based medicine Web Dobutamine of bias sites, such as that of the Agency for Healthcare Research and Quality CMR: k=11 Searches were divided into 4 categories: CAD and/or Inclusion criteria: PET: k=14 ischemia detection and A systematic search of the literature, using validated British Medical Journal filters diagnosis; CAD for diagnosis and prognosis, was used to identify the best evidence for use of prognostication; myocardial CTCA and CMR. viability detection; and viability prognostication Exclusion criteria: Analysis at patient and None reported segment level Chen et al. () 55% To use direct comparative Search period: Both SP-CMR and ICA: DS cut-off (6/11) studies or RCTs to compare SPECT evaluated in at 50% or above China Publication date no later than June 2013 the accuracy of CMR and the same patient Moderate SPECT for the detection of population: k=6 Databases searched: quality with obstructive CAD a moderate PubMed, EMBASE, Web of Science and the Cochrane Library risk of bias Inclusion criteria: Adult patients with CAD or Direct comparative studies or randomised controlled trials. The data reported in the suspected of having CAD primary studies were sufficient for the calculation of true-positive, false-positive, Analysis at patient and true-negative or false-negative values. coronary artery level Exclusion criteria: Review articles, letters, comments, case reports and unpublished articles were excluded.
with MPI without addressing the diagnostic accuracy of coronary artery stenosis or occlusion, and studies including patients treated with coronary stents or bypass grafts Beanlands et al. () Canada 18% (2/11) Poor quality with a high risk of bias To define Canadian recommendations for the clinical use of advanced imaging modalities Searches were divided into 4 categories: CAD and/or ischemia detection and diagnosis; CAD prognostication; myocardial viability detection; and viability prognostication Analysis at patient and segment level Search period: Up to June 2005 Databases searched: Medline, EMBASE, Cochrane library, and other evidence-based medicine Web sites, such as that of the Agency for Healthcare Research and Quality Inclusion criteria: A systematic search of the literature, using validated British Medical Journal filters for diagnosis and prognosis, was used to identify the best evidence for use of CTCA and CMR. Exclusion criteria: None reported Multidetector CTCA 16-slice: k=19 64slice: k=4 Dobutamine k=11 PET: k=14 ICA: DS cut-off at 50% or above Chen et al. () China 55% (6/11) Moderate quality with a moderate risk of bias To use direct comparative studies or RCTs to compare the accuracy of CMR and SPECT for the detection of obstructive CAD Adult patients with CAD or suspected of having CAD Analysis at patient and coronary artery level Search period: Publication date no later than June 2013 Databases searched: PubMed, EMBASE, Web of Science and the Cochrane Library Inclusion criteria: Direct comparative studies or randomised controlled trials. The data reported in the primary studies were sufficient for the calculation of true-positive, false-positive, true-negative or false-negative values. Exclusion criteria: Review articles, letters, comments, case reports and unpublished articles were excluded. Both SP-CMR and SPECT evaluated in the same patient population: k=6 ICA: DS cut-off at 50% or above CMR:
1237-AssessmentReport-Final.docx