79 pts (40 VCE 39 PE) Not specified RCT VCE – 72.5% et al 2015(8) VCE vs PE PE – 48.7% Aniwan et al DBE vs VCE 30 pts; massive OGIB Not specified DBE – 87% 2014(9) VCE 60% He et al Randomized, 127 pts with OGIB Capsule MSCT – 47.56% 2014(10) single blinded, including overt and retention - CE – 68.66% MSCT vs CE obscure 1.47% Katsinelos et al Prospective CE 66.9% Not specified 118 pts 2014(11) multicenter median age 66 Khan et al Retrospective 122 pts 70% with Overall diagnostic Not specified 2013(12) obscure GI bleeding yield 52% Leung et al Prospective 60 pts with OGIB Not specified CE – 53.3% 2012(13) randomized Angio - 20% CE vs angiography Shishido et al Prospective 118 pts with OGIB CE - 44.9% Not specified 2012(14) (mean age 62.9 +/- 18.4) CE vs DBE DBE – 53.4% Lecleire et al Retrospective 5744 pts with severe CE – 67% Not specified 2012(15) OGIB who underwent emergency CE in 24-48 hrs following negative upper and lower endoscopy Heo et al Retrospective 30 pts with OGIB CE - 57% Not specified 2012(16) receiving CE after negative CT enterography Cuyle et al (17) Retrospective 120 pts with OGIB CE – 47.5% 1 case capsule retention No difference between overt and occult group Presence of CVS comorbidity was assoc with statistically significant increase in diagnostic yield Calabrese et al Retrospective 346 pts with OGIB CE - 59.5% Capsule
et al 2015(8) RCT VCE vs PE 79 pts (40 VCE 39 PE) VCE – 72.5% PE – 48.7% Not specified Aniwan et al 2014(9) DBE vs VCE 30 pts; massive OGIB DBE – 87% VCE 60% Not specified He et al 2014(10) Randomized, single blinded, MSCT vs CE 127 pts with OGIB including overt and obscure MSCT – 47.56% CE – 68.66% Capsule retention - 1.47% Katsinelos et al 2014(11) Prospective multicenter 118 pts median age 66 CE 66.9% Not specified Khan et al 2013(12) Retrospective 122 pts 70% with obscure GI bleeding Overall diagnostic yield 52% Not specified Leung et al 2012(13) Prospective randomized CE vs angiography 60 pts with OGIB CE – 53.3% Angio - 20% Not specified Shishido et al 2012(14) Prospective CE vs DBE 118 pts with OGIB (mean age 62.9 +/- 18.4) CE - 44.9% DBE – 53.4% Not specified Lecleire et al 2012(15) Retrospective 5744 pts with severe OGIB who underwent emergency CE in 24-48 hrs following negative upper and lower endoscopy CE – 67% Not specified Heo et al 2012(16) Retrospective 30 pts with OGIB receiving CE after negative CT enterography CE - 57% Not specified Cuyle et al (17) Retrospective 120 pts with OGIB CE – 47.5% No difference between overt and occult group Presence of CVS comorbidity was assoc with statistically significant increase in diagnostic yield 1 case capsule retention Calabrese et al Retrospective 346 pts with OGIB CE - 59.5% Capsule
Final%20report%20from%20the%20Gastroenterology%20Clinical%20Committee.docx