OECD TG 404 Test method: Draize scores: Time Animal # treatment 1 2 3 Erythema 1 hour a1 0 1 24 hours 0 0 0 48 hours 0 0 0 72 hours 0 0 0 Oedema Draize scores for oedema were zero for all animals during the study. a see Attachment 1 for Draize scales Yellow coloured staining was noted at all treated skin sites Comment: throughout the study. This staining did not interfere with evaluation of skin reactions. The notified chemical was slightly irritating to the skin of Result: rabbits. 9.1.5 Eye Irritation (Safepharm Laboratories Ltd, 1998c) Rabbit/New Zealand Species/strain: 3 Number/sex of animals: 72 hours Observation period: A dose of 0.1 mL (65 mg notified chemical) was applied to Method of administration: conjunctival sac of one eye. The untreated eye served as the control. OECD TG 405 Test method: Draize scores of unirrigated eyes: Time after instillation
Test method: OECD TG 404 Draize scores: Time Animal # treatment 1 2 3 Erythema 1 hour a1 0 1 24 hours 0 0 0 48 hours 0 0 0 72 hours 0 0 0 Oedema Draize scores for oedema were zero for all animals during the study. a see Attachment 1 for Draize scales Comment: Yellow coloured staining was noted at all treated skin sites throughout the study. This staining did not interfere with evaluation of skin reactions. Result: The notified chemical was slightly irritating to the skin of rabbits. 9.1.5 Eye Irritation (Safepharm Laboratories Ltd, 1998c) Species/strain: Rabbit/New Zealand Number/sex of animals: 3 Observation period: 72 hours Method of administration: A dose of 0.1 mL (65 mg notified chemical) was applied to conjunctival sac of one eye. The untreated eye served as the control. Test method: OECD TG 405 Draize scores of unirrigated eyes: Time after instillation
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