Four clinical of MS have been described: Four clinical types of MS have been described: relapsing/remitting MS (RRMS), primary relapsing/remitting MS (RRMS), primary progressive MS (PPMS), secondary progressive MS progressive MS (PPMS), secondary progressive MS (SPMS), and progressive/relapsing MS (PRMS). (SPMS), and progressive/relapsing MS (PRMS). Diagnosis requires two or more episodes of New evidence and consensus in 2010 has led to symptoms and two or more signs that reflect further revision of the McDonald Criteria for pathology in anatomically non-contiguous white diagnosis of multiple sclerosis. The use of imaging matter tracts of the CNS. Symptoms must last >24 for demonstration of dissemination of central hours and occur as separate episodes at least one nervous system lesions in space and time is month apart. At least one of the two signs must be defined. The 2010 revisions simplify the diagnostic present on neurological examination, while the criteria, maintain their diagnostic sensitivity and other may be detected by paraclinical tests such as specificity and support earlier diagnosis and more intrathecal IgG (oligoclonal bands and visual evoked uniform and widespread use. (Ann Neurol 2011 potentials). Feb; 69(2): 292-302. Diagnosis is Clinically definite Yes neurologist By which specialty Yes - Neurologist Diagnosis to be made by a neurologist required RRMS as defined according to McDonald 2010 (A) by McDonald et al (2001) criteria Diagnosis Diagnosis must be No By trial specialty must be confirmed by a verified neurologist Exclusion Primary progressive MS. Primary progressive MS. Unchanged Criteria
Four clinical of MS have been described: relapsing/remitting MS (RRMS), primary progressive MS (PPMS), secondary progressive MS (SPMS), and progressive/relapsing MS (PRMS). Diagnosis requires two or more episodes of symptoms and two or more signs that reflect pathology in anatomically non-contiguous white matter tracts of the CNS. Symptoms must last >24 hours and occur as separate episodes at least one month apart. At least one of the two signs must be present on neurological examination, while the other may be detected by paraclinical tests such as intrathecal IgG (oligoclonal bands and visual evoked potentials). Four clinical types of MS have been described: relapsing/remitting MS (RRMS), primary progressive MS (PPMS), secondary progressive MS (SPMS), and progressive/relapsing MS (PRMS). New evidence and consensus in 2010 has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time is defined. The 2010 revisions simplify the diagnostic criteria, maintain their diagnostic sensitivity and specificity and support earlier diagnosis and more uniform and widespread use. (Ann Neurol 2011 Feb; 69(2): 292-302. Diagnosis is required Clinically definite RRMS as defined by McDonald et al (2001) criteria Yes neurologist By which specialty Yes - Neurologist Diagnosis to be made by a neurologist according to McDonald 2010 (A) Diagnosis must be verified Diagnosis must be confirmed by a neurologist No By specialty Exclusion Criteria Primary progressive MS. Primary progressive MS. Unchanged trial
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