the notified chemical was of very low oral Result: toxicity in rats Dermal Toxicity (McRae, 1996a) rat/Sprague-Dawley Species/strain: 5/sex Number/sex of animals: 14 days Observation period: the notified chemical was spread evenly over the Method of administration: clipped skin, then covered with an occlusive dressing for 24 slightly low bodyweight gains were recorded for 1 Clinical observations: male and 2 females on day 8, and 2 males and 1 female on day 15. nil Mortality: nil Morphological findings: OECD TG 402 (Organisation for Economic Co- Test method: operation and Development, 1995-1996) > 2 000 mg/kg LD50: the Draize scores were all zero in rats at 2 Remarks: 000 mg/kg for 15 days in this the notified chemical was of low dermal toxicity in Result: rats Inhalation Toxicity No inhalation toxicity study was available. Skin Irritation (Parcell, 1996b) rabbit/New Zealand White Species/strain: 3 males Number/sex of animals: 13 days Observation period: the notified chemical (0.5 mL) was applied to Method of administration: intact skin under a semi-occlusive dressing for 4 hours.
Result: the notified chemical was of very low oral toxicity in rats Dermal Toxicity (McRae, 1996a) Species/strain: rat/Sprague-Dawley Number/sex of animals: 5/sex Observation period: 14 days Method of administration: the notified chemical was spread evenly over the clipped skin, then covered with an occlusive dressing for 24 Clinical observations: slightly low bodyweight gains were recorded for 1 male and 2 females on day 8, and 2 males and 1 female on day 15. Mortality: nil Morphological findings: nil Test method: OECD TG 402 (Organisation for Economic Co- operation and Development, 1995-1996) LD50: > 2 000 mg/kg Remarks: the Draize scores were all zero in rats at 2 000 mg/kg for 15 days in this Result: the notified chemical was of low dermal toxicity in rats Inhalation Toxicity No inhalation toxicity study was available. Skin Irritation (Parcell, 1996b) Species/strain: rabbit/New Zealand White Number/sex of animals: 3 males Observation period: 13 days Method of administration: the notified chemical (0.5 mL) was applied to intact skin under a semi-occlusive dressing for 4 hours.
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