Eye Irritation (6) rabbit/not provided Species/strain: 3/not provided Number/sex of animals: 72 days Observation period: undiluted; not provided Method of administration: Draize scores (9) of unirrigated slight conjunctival redness was observed in all 3 eyes: animals, reversible within 48 hours according to OECD guidelines (8) Test method: the notified chemical was a slight eye irritant in Result: rabbits Skin Sensitisation (7) guinea pig/not provided Species/strain: not provided Number of animals: 5% (w/v) of notified chemical in arachis oil injected; Induction procedure: undiluted chemical for topical application (time not recorded) occluded application of undiluted notified chemical Challenge procedure: no evidence of contact hypersensitivity Challenge outcome: (details not provided) according to OECD guidelines (8) Test method: the notified chemical was not a skin sensitiser in Result: albino guinea pigs Repeated Dose Toxicity (11) rat/Wistar Species/strain: 60/sex (5/sex/dose group and 5/sex/ recovery Number/sex of animals: group ) gavage; vehicle polyethylene glycol 400 Method of administration:
Eye Irritation (6) Species/strain: rabbit/not provided Number/sex of animals: 3/not provided Observation period: 72 days Method of administration: undiluted; not provided Draize scores (9) of unirrigated eyes: slight conjunctival redness was observed in all 3 animals, reversible within 48 hours Test method: according to OECD guidelines (8) Result: the notified chemical was a slight eye irritant in rabbits Skin Sensitisation (7) Species/strain: guinea pig/not provided Number of animals: not provided Induction procedure: 5% (w/v) of notified chemical in arachis oil injected; undiluted chemical for topical application (time not recorded) Challenge procedure: occluded application of undiluted notified chemical Challenge outcome: no evidence of contact hypersensitivity (details not provided) Test method: according to OECD guidelines (8) Result: the notified chemical was not a skin sensitiser in albino guinea pigs Repeated Dose Toxicity (11) Species/strain: rat/Wistar Number/sex of animals: 60/sex (5/sex/dose group and 5/sex/ recovery group ) Method of administration: gavage; vehicle polyethylene glycol 400
NA619FR.docx