Introduction; 4.2 Membrane Separation Processes: of membrane; Membrane processes; Nature of synthetic membranes; General membrane equation; Cross-flow microfiltration; Ultrafiltration; Reverse osmosis; Membrane modules. 4.3 Advanced Downstream Processing in Biotechnology: Introduction; Protein products; Cell disruption; Protein purification; General problems associated with conventional techniques; Fluidised bed adsorption; Design and operation of fluidised beds; Interfaced and integrated fluidised bed/expanded bed system. 4.4 Immobilized Enzymes and Immobilized Cells: Advantages of immobilized biocatalysts in general; Methods of immobilizing enzymes; Methods for the immobilization of cells; Practical Application of Immobilized Biological Catalyst Systems; Bioreactors Designs for Usage in Biocatalysis ; Immobilised cell reactor(ICR) experiments and ICR rate model. List of experiment 1 Amylase Production: Screening, Optimization, production and Purification (affinity chromatography) 2 Protease Production: Screening, Optimization, Production and Purification (Salt precipitation, ion exchange chromatography) 3 Immobilization of enzyme 4 Estimation aeration efficiency 5 Reverse micelle formation 6 Screening of Organic acid producer microorganism 7 Screening of Antibiotic producer microorganism 8 Operation of fermentation 9 Sterility testing Reference Book :- No Book Name 1 Modern Industrial Microbiology and biotechnology. Okafor 2 Biochemical Engineering and Biotechnology. Najafpour 3 Biochemical engineering. Shigeo 4 Principles of fermentation technology. Whittaker 5 Microbial Biotechnology. Alexander 6 Techniques in Applied Microbiology Sikyta 7 Fermentation and Biochemical Engineering Handbook. 8 Practical Fermentation Technology. Mcneil 9 Bioprocess engineering Principle. Doran 10 Modern Biotechnology. Nathan
4.2 Membrane Separation Processes: Introduction; of membrane; Membrane processes; Nature of synthetic membranes; General membrane equation; Cross-flow microfiltration; Ultrafiltration; Reverse osmosis; Membrane modules. 4.3 Advanced Downstream Processing in Biotechnology: Introduction; Protein products; Cell disruption; Protein purification; General problems associated with conventional techniques; Fluidised bed adsorption; Design and operation of fluidised beds; Interfaced and integrated fluidised bed/expanded bed system. 4.4 Immobilized Enzymes and Immobilized Cells: Advantages of immobilized biocatalysts in general; Methods of immobilizing enzymes; Methods for the immobilization of cells; Practical Application of Immobilized Biological Catalyst Systems; Bioreactors Designs for Usage in Biocatalysis ; Immobilised cell reactor(ICR) experiments and ICR rate model. List of experiment 1 Amylase Production: Screening, Optimization, production and Purification (affinity chromatography) 2 Protease Production: Screening, Optimization, Production and Purification (Salt precipitation, ion exchange chromatography) 3 Immobilization of enzyme 4 Estimation aeration efficiency 5 Reverse micelle formation 6 Screening of Organic acid producer microorganism 7 Screening of Antibiotic producer microorganism 8 Operation of fermentation 9 Sterility testing Reference Book :- No Book Name 1 Modern Industrial Microbiology and biotechnology. Okafor 2 Biochemical Engineering and Biotechnology. Najafpour 3 Biochemical engineering. Shigeo 4 Principles of fermentation technology. Whittaker 5 Microbial Biotechnology. Alexander 6 Techniques in Applied Microbiology Sikyta 7 Fermentation and Biochemical Engineering Handbook. 8 Practical Fermentation Technology. Mcneil 9 Bioprocess engineering Principle. Doran 10 Modern Biotechnology. Nathan
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