Examples of OST and SDC trials. Each large circle represents an individual trial; Figure 1. represent OST trials 1-4 while and represent interspersed SDC trials. OST1-OST4 SDC1 SDC2 The small circles represent 18 possible stimulus locations in the apparatus. A letter represents a specific odor in a location; letters & indicate different odor stimuli (e.g. A, B, C, D, X, Y A= apple, banana). A plus sign next to a letter (e.g. indicates that selection of that stimulus B= A+) (A) would produce a sugar pellet. A minus (e.g. indicates that no pellet is available for B-) selection of that odor (B). Notice that possible negative stimuli increase as OST trials increment: 1 possible negative (A) for 2 (A, B) for 3 (A, B, C) for and so on. During all OST2, OST3, OST4, SDC trials selection of X (X+) always produced a sugar pellet, while a selection of Y (Y-) did not. Means for percent correct, consecutive correct, and latency for the PCP group. Figure 2. Top shows the effects of PCP on percent correct (circles) and omissions (bars) for the OST panel (closed circles, dark bars) and SDC task (open circles, light bars). shows span Middle panel (closed circles) and longest run (open circles). shows latency to first response for Bottom panel OST (closed circles) and SDC task (open circles). indicate SEM. Vertical lines Individual subject graphs show the effects of PCP on percent correct (circles) and Figure 3. omissions (bars) for the OST (closed circles, dark bars) and SDC task (open circles, light bars).
Figure 1. Examples of OST and SDC trials. Each large circle represents an individual trial; OST1-OST4 represent OST trials 1-4 while SDC1 and SDC2 represent interspersed SDC trials. The small circles represent 18 possible stimulus locations in the apparatus. A letter represents a specific odor in a location; letters A, B, C, D, X, & Y indicate different odor stimuli (e.g. A= apple, B= banana). A plus sign next to a letter (e.g. A+) indicates that selection of that stimulus (A) would produce a sugar pellet. A minus (e.g. B-) indicates that no pellet is available for selection of that odor (B). Notice that possible negative stimuli increase as OST trials increment: 1 possible negative (A) for OST2, 2 (A, B) for OST3, 3 (A, B, C) for OST4, and so on. During all SDC trials selection of X (X+) always produced a sugar pellet, while a selection of Y (Y-) did not. Figure 2. Means for percent correct, consecutive correct, and latency for the PCP group. Top panel shows the effects of PCP on percent correct (circles) and omissions (bars) for the OST (closed circles, dark bars) and SDC task (open circles, light bars). Middle panel shows span (closed circles) and longest run (open circles). Bottom panel shows latency to first response for OST (closed circles) and SDC task (open circles). Vertical lines indicate SEM. Figure 3. Individual subject graphs show the effects of PCP on percent correct (circles) and omissions (bars) for the OST (closed circles, dark bars) and SDC task (open circles, light bars).
NMDAMathews_ECPdraft.docx