Author/year Number Age Patient Definition Healing Healing Follow-up Factors related to outcome Mortality Comments of selection of healing rate time patients 10 64 (50-83) Diabetes + Yes 8/10 64 days 3 years Not reported 0% Case series of efficacy of Walsh et al (DM) (mean) calcanectomy. Small patient sample. 2013120 non diabetes (5/7 in 77 (50-87) DM (non DM) patients) 37 62 ±14 Diabetes No 89% 6 (4-7) Minimum 1 Not reported 0% 11% major amputation Shojaiefard et months year al 2013115 42 61±16.6 Diabetes + No Not Not reported 41±26 Not reported 12% Study on partial calcanectomy for Oliver et al non diabetes reported months heel ulcers. Question is whether 2015121 64±16 resection of more or less than 50% of calcaneus has an influence on outcome. It does not. 29% major amputation. 50 52.9±11 Diabetes Yes 54% 20 Not Not reported 0% from Sudan. Compares Yosuf et al (cohort specified outcome of forefoot ulcers vs heel 2015122 100 ulcers. patients) 63 56 (range Diabetes Yes 84% 1991-2003 6 years Smoking, heel 3% (30 day Studies free flap transfer for heel Kallio et al 21) nephropathy, ulcer diameter mortality) ulcers. 2015117 56% >10 cm associated with Amputation rate 11% (30 day amp 33% increased amputation risk rate). 30% major amputation during follow-up. 12 73 (65-79) Diabetes No 75% Not reported 2 weeks to 3 Not reported 8% Included patients with near total Lin et al years occlusive PVD. 2016116 Primary wound closure in all cases. 768 73 (17-98) Diabetes Yes 66% 17 (1-416) Until Vascular surgery, 25% 12% major amputation Örneholm et weeks healing or nephropathy, oedema, al 2016Paper death creatinine <91 µmol/L III
Author/year Number of patients Age Patient selection Definition of healing Healing rate Healing time Follow-up Factors related to outcome Mortality Comments Walsh et al 2013120 10 64 (50-83) (DM) 77 (50-87) (non DM) Diabetes + non diabetes Yes 8/10 (5/7 in DM patients) 64 days (mean) 3 years Not reported 0% Case series of efficacy of calcanectomy. Small patient sample. Shojaiefard et al 2013115 37 62 ±14 Diabetes No 89% 6 (4-7) months Minimum 1 year Not reported 0% 11% major amputation Oliver et al 2015121 42 61±16.6 64±16 Diabetes + non diabetes No Not reported Not reported 41±26 months Not reported 12% Study on partial calcanectomy for heel ulcers. Question is whether resection of more or less than 50% of calcaneus has an influence on outcome. It does not. 29% major amputation. Yosuf et al 2015122 50 (cohort 100 patients) 52.9±11 Diabetes Yes 54% 20 Not specified Not reported 0% from Sudan. Compares outcome of forefoot ulcers vs heel ulcers. Kallio et al 2015117 63 56 (range 21) Diabetes Yes 84% 56% 33% 1991-2003 6 years Smoking, heel nephropathy, ulcer diameter >10 cm associated with increased amputation risk 3% (30 day mortality) Studies free flap transfer for heel ulcers. Amputation rate 11% (30 day amp rate). 30% major amputation during follow-up. Lin et al 2016116 12 73 (65-79) Diabetes No 75% Not reported 2 weeks to 3 years Not reported 8% Included patients with near total occlusive PVD. Primary wound closure in all cases. Örneholm et al 2016Paper III 768 73 (17-98) Diabetes Yes 66% 17 (1-416) weeks Until healing or death Vascular surgery, nephropathy, oedema, creatinine <91 µmol/L 25% 12% major amputation
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