0.5 mL of the test substance as a single 4 hour Method of administration: occlusive application to intact skin OECD TG 404 Test method: Draize scores: Time after Animal # treatment 1 2 3 (days) Erythema 1 1a 0 0 2 1 0 0 3 0 0 0 Oedema 1 0 0 0 2 0 0 0 3 0 0 0 a see Attachment 1 for Draize scales The relative humidity in the animal room was out of for Comment: 4 of 5 intervals. The notified chemical was slightly irritating to the skin of Result: rabbits. 9.1.5 Eye Irritation (Huntington Life Sciences, New Zealand White rabbits Species/strain: 1 male, 2 females Number/sex of animals: 3 days Observation period: 0.1 mL of the test substance into the conjunctival sac of one Method of administration: eye of each animal. OECD TG 405 Test method: The only irritation observed was a slight to moderate Comment: conjunctival redness and severe discharge in all 3 animals 1 hour post application. effects had cleared by 24 hours post application. No eye irritation was observed-all Draize scores were zero. The notified chemical was not irritating to the eyes of Result: rabbits.
Method of administration: 0.5 mL of the test substance as a single 4 hour application to intact skin Test method: OECD TG 404 Draize scores: Time after Animal # treatment (days) 1 2 3 Erythema 1 1a 0 0 2 1 0 0 3 0 0 0 Oedema 1 0 0 0 2 0 0 0 3 0 0 0 a see Attachment 1 for Draize scales Comment: The relative humidity in the animal room was out of for 4 of 5 intervals. Result: The notified chemical was slightly irritating to the skin of rabbits. 9.1.5 Eye Irritation (Huntington Life Sciences, Species/strain: New Zealand White rabbits Number/sex of animals: 1 male, 2 females Observation period: 3 days Method of administration: 0.1 mL of the test substance into the conjunctival sac of one eye of each animal. Test method: OECD TG 405 Comment: The only irritation observed was a slight to moderate conjunctival redness and severe discharge in all 3 animals 1 hour post application. effects had cleared by 24 hours post application. No eye irritation was observed-all Draize scores were zero. Result: The notified chemical was not irritating to the eyes of rabbits. occlusive
NA967FR.docx