Engineering Design Challenge Rubric 4 3 2 1 NDDM* successfully NDDM successfully NDDM successfully touches NDDM successfully touches Targeting of cancer attaches to and bound attaches to, but may not at least one cancer cell and at least one cancer cell and to at least one cancer cell stay to, at least one only one normal cells two or more normal cells and zero normal cells cancer cell and zero normal cells Elimination of NDDM causes 100% NDDM causes 50-99% NDDM causes minimal NDDM causes damage to cancer cells destruction of at one destruction of at least one damage to at least one both cancer and normal cells cancer cell cancer cell cancer cell Materials At least six different At least five different Only 3 different materials Only 2 different materials are materials are chosen materials are chosen based are chosen at random, with chosen with no thought as to based on structure and on structure and function of little thought as to function function function of materials materials Delivery NDDM is easily delivered NDDM is delivered through NDDM is delivered through NDDM is delivered through a through a modeled a modeled bloodstream a modeled bloodstream with modeled bloodstream with bloodstream to the target with some difficulty to the major difficulty to an major difficulty to an organ. All parts of model target organ. All parts of unspecified location. unspecified location. Missing are accurately labeled. model are accurately Missing one accurate label two or more accurately labels labeled. on model. on model. Scale (note: it It is clear that NDDM is at It is clear that NDDM is NDDM and target cells are NDDM is larger than target would be least half of the size of the smaller than target cells about the same size impossible to make target cells a model exactly to scale!) * - Nano-drug delivery mechanism
Engineering Design Challenge Rubric 4 3 2 1 Targeting of cancer NDDM* successfully attaches to and bound to at least one cancer cell and zero normal cells NDDM successfully attaches to, but may not stay to, at least one cancer cell and zero normal cells NDDM successfully touches at least one cancer cell and only one normal cells NDDM successfully touches at least one cancer cell and two or more normal cells Elimination of cancer cells NDDM causes 100% destruction of at one cancer cell NDDM causes 50-99% destruction of at least one cancer cell NDDM causes minimal damage to at least one cancer cell NDDM causes damage to both cancer and normal cells Materials At least six different materials are chosen based on structure and function of materials At least five different materials are chosen based on structure and function of materials Only 3 different materials are chosen at random, with little thought as to function Only 2 different materials are chosen with no thought as to function Delivery NDDM is easily delivered through a modeled bloodstream to the target organ. All parts of model are accurately labeled. NDDM is delivered through a modeled bloodstream with some difficulty to the target organ. All parts of model are accurately labeled. NDDM is delivered through a modeled bloodstream with major difficulty to an unspecified location. Missing one accurate label on model. NDDM is delivered through a modeled bloodstream with major difficulty to an unspecified location. Missing two or more accurately labels on model. Scale (note: it would be impossible to make a model exactly to scale!) It is clear that NDDM is at least half of the size of the target cells It is clear that NDDM is smaller than target cells NDDM and target cells are about the same size NDDM is larger than target * - Nano-drug delivery mechanism
Nano.chemo_.printables.docx