NHL Burkitt-type Lymphoma Height cm – R- MTX Ara C Weight kg This alternates with Hyper-CVAD BSA M2 Infusion rate = mL/hr 125 X BSA Day Date Time Dose Route Instructions Doctor Nurse Check Start Stop 2100 Folinic acid 15 mg IV 3 2100 *Cytarabine mg/m2 mg IV In 500ml 0.9% saline over 2 hrs (Q12H) 1000ml 0.9S + 30mmol KCl and 50mmol NaHCO3 IV Infuse at 125ml/m2/hr ml/hr IV Infuse at 125ml/m2/hr 1000ml 0.9S + 30mmol KCl and 50mmol NaHCO3 ml/hr 4 Folinic acid 15 mg IV 0300 Dexamethasone 8 mg PO 30-60 minutes prior to chemo 0800 0800 Ondansetron 8 mg PO/IV 30-60 minutes to chemo Aim <0.1micromol/l. If > 0.1micromol/l increase folinic acid to 50mg IV Q12H until the level is 0900 Methotrexate level <0.1micromol/l. Notify labs if MTX levels will be required over a weekend. 0900 Folinic acid 15 mg IV 0900 *Cytarabine mg/m2 mg IV In 500ml 0.9% saline over 2 hrs (Q12H) Folinic acid 15 mg PO 1500 Ondansetron 8 mg PO/IV 2000 Aim <0.1micromol/l. If > 0.1micromol/l increase folinic acid to 50mg IV Q12H until the level is Folinic acid 15 mg 2100 <0.1micromol/l. Notify labs if MTX levels will be required over a weekend CHART ON QMR4. 5 0800 Dexamethasone 8 mg PO 0800 Ondansetron 8 mg PO/IV 1700 Pegylated GCSF 6 mg SC See intrathecal chemotherapy chart Cytarabine 100mg IT 8
NHL – Burkitt-type Lymphoma R- MTX Ara C This alternates with Hyper-CVAD Height cm Weight kg BSA M2 Infusion rate 125 X BSA = mL/hr Day Date Time Dose Route Instructions Doctor Nurse Check Start Stop 3 2100 Folinic acid 15 mg IV 2100 *Cytarabine mg/m2 (Q12H) mg IV In 500ml 0.9% saline over 2 hrs 1000ml 0.9S + 30mmol KCl and 50mmol NaHCO3 IV Infuse at 125ml/m2/hr ml/hr 4 1000ml 0.9S + 30mmol KCl and 50mmol NaHCO3 IV Infuse at 125ml/m2/hr ml/hr 0300 Folinic acid 15 mg IV 0800 Dexamethasone 8 mg PO 30-60 minutes prior to chemo 0800 Ondansetron 8 mg PO/IV 30-60 minutes to chemo 0900 Methotrexate level Aim <0.1micromol/l. If > 0.1micromol/l increase folinic acid to 50mg IV Q12H until the level is <0.1micromol/l. Notify labs if MTX levels will be required over a weekend. 0900 Folinic acid 15 mg IV 0900 *Cytarabine mg/m2 (Q12H) mg IV In 500ml 0.9% saline over 2 hrs 1500 Folinic acid 15 mg PO 2000 Ondansetron 8 mg PO/IV 2100 Folinic acid 15 mg Aim <0.1micromol/l. If > 0.1micromol/l increase folinic acid to 50mg IV Q12H until the level is <0.1micromol/l. CHART ON QMR4. Notify labs if MTX levels will be required over a weekend 5 0800 Dexamethasone 8 mg PO 0800 Ondansetron 8 mg PO/IV 1700 Pegylated GCSF 6 mg SC 8 Cytarabine 100mg IT See intrathecal chemotherapy chart
NHL%20Burkitt-type%20lymphoma%20Ritux%20MTX%20cytarabine%20cycles%202%20and%204.docx