rat/ Sprague-Dawley. Species/strain: 5/sex Number/sex of animals: 14 days. Observation period: Under semi-occluded gauze dressing for 24 hours, dose Method of administration: 2000 mg/kg. OECD TG 402 Test method: None. Mortality: None. Clinical observations: None. Morphological findings: All scores zero. Draize scores: > 2000 mg/kg. LD50: The notified chemical was of low dermal toxicity in rats. Result: Inhalation Toxicity Data not provided. 9.1.4 Skin Irritation (Safepharm Laboratories, rabbit/New Zealand White (NZW). Species/strain: 3 males. Number/sex of animals: 7 days. Observation period: 0.5 mL, single, 4-hour, semi-occluded application. Method of administration: OECD TG 404 Test method: Draize scores: Time after Animal treatment 1 2 3 (days) Erythema 1 hour 1a 1 1
Species/strain: rat/ Sprague-Dawley. Number/sex of animals: 5/sex Observation period: 14 days. Method of administration: Under semi-occluded gauze dressing for 24 hours, dose 2000 mg/kg. Test method: OECD TG 402 Mortality: None. Clinical observations: None. Morphological findings: None. Draize scores: All scores zero. LD50: > 2000 mg/kg. Result: The notified chemical was of low dermal toxicity in rats. Inhalation Toxicity Data not provided. 9.1.4 Skin Irritation (Safepharm Laboratories, Species/strain: rabbit/New Zealand White (NZW). Number/sex of animals: 3 males. Observation period: 7 days. Method of administration: 0.5 mL, single, 4-hour, semi-occluded application. Test method: OECD TG 404 Draize scores: Time after Animal treatment (days) 1 2 3 Erythema 1 hour 1a 1 1
NA907FR.docx