Recovery group: no salivation was observed in the test or control group concentration and prothrombin time were observed; Haematology in females, leukocyte count was increased in males, platelet and reticulocyte counts were in males, Test increased while in females, hemoglobin high dose: increased in concentration and leukocyte counts were decreased platelet counts and decreased the various changes in the haematological in parameters tested on animals of the treated and haemoglobin control groups did not exceed the range of concentration, historical data for the testing laboratory and mean Recovery test therefore the above changes were considered to be corpuscular group: of minor toxicological importance haemoglobin Clinical in males, decreased aspartate amino transferase chemistry: Recovery (AST) and albumin globulin ratio were observed test group: in females, decreased glucose and chloride, and Test low dose: increased total protein and albumin were observed in both sexes, increased -glutamyl-p-nitroanilide high dose: in substrate, total cholesterol and calcium were females, observed increased albumin and in females, decreased alkaline phosphatase (ALP) decreased and albumin globulin ratio, and increased total chloride cholesterol were observed was observed the decrease in AST in males in high dose test
Recovery group: no salivation was observed in the test or control group Haematology Test high dose: Recovery test group: in males, increased in platelet counts and decreased in haemoglobin concentration, mean corpuscular haemoglobin concentration and prothrombin time were observed; in females, leukocyte count was increased in males, platelet and reticulocyte counts were increased while in females, hemoglobin concentration and leukocyte counts were decreased the various changes in the haematological parameters tested on animals of the treated and control groups did not exceed the range of historical data for the testing laboratory and therefore the above changes were considered to be of minor toxicological importance Clinical chemistry: Test low dose: high dose: Recovery test group: in females, increased albumin and decreased chloride was observed in males, decreased aspartate amino transferase (AST) and albumin globulin ratio were observed in females, decreased glucose and chloride, and increased total protein and albumin were observed in both sexes, increased -glutamyl-p-nitroanilide substrate, total cholesterol and calcium were observed in females, decreased alkaline phosphatase (ALP) and albumin globulin ratio, and increased total cholesterol were observed the decrease in AST in males in high dose test
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