9.1.1 Oral Toxicity (2) Species/strain: rat/Sprague Dawley Number/sex of animals: 5/sex Observation period: 14 days Method of administration: gavage Clinical observations: none related to treatment Mortality: none Morphological findings: none related to treatment Test method: similar to OECD guidelines (7) > 5 000 mg.kg-1 LD50: Result: the notified chemical was of low oral toxicity in rats in a limit test - single dose of 5 000 mg.kg-1 9.1.2 Dermal Toxicity (3) Species/strain: rabbit/New Zealand White Number/sex of animals: 5/sex Observation period: 14 days Method of administration: semiocclusive dressing; 24 hour treatment Clinical observations: moderate to marked erythema were noted on 8 rabbits for 48 and on 7 rabbits for 72 moderate to marked oedema were on 5 rabbits for 48 hours and on one rabbit for 72 scaling was observed on the backs of all rabbits up to day 7; all observations resolved by day 14 Mortality: none
9.1.1 Oral Toxicity (2) Species/strain: Number/sex of animals: Observation period: Method of administration: Clinical observations: Mortality: Morphological findings: Test method: rat/Sprague Dawley 5/sex 14 days gavage none related to treatment none none related to treatment similar to OECD guidelines (7) LD50: > 5 000 mg.kg-1 Result: the notified chemical was of low oral toxicity in rats in a limit test - single dose of 5 000 mg.kg-1 9.1.2 Dermal Toxicity (3) Species/strain: rabbit/New Zealand White Number/sex of animals: 5/sex Observation period: 14 days Method of administration: semiocclusive dressing; 24 hour treatment Clinical observations: moderate to marked erythema were noted on 8 rabbits for 48 and on 7 rabbits for 72 moderate to marked oedema were on 5 rabbits for 48 hours and on one rabbit for 72 scaling was observed on the backs of all rabbits up to day 7; all observations resolved by day 14 Mortality: none
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