Dermal Toxicity (Krueger, 1997b) rat/Wistar Species/strain: 5/sex Number/sex of animals: 14 days Observation period: the undiluted notified chemical was given dermally Method of administration: for 24 hours under a semi-occlusive dressing moderate to severe dermal irritation was observed Clinical observations: in animals none Mortality: none Morphological findings: according to OECD Guidelines (Organisation for Test method: Economic Co-operation and Development, 1995- 1996) > 2 000 mg.kg-1 LD50: the notified chemical was of low acute Result: dermal toxicity in rats Skin Irritation (Krueger, 1997c) rabbit/White Russian Species/strain: 3 females Number/sex of animals: 14 days Observation period: a single application to the shorn intact skin under a Method of administration: semi-occlusive dressing for 4 hours
Dermal Toxicity (Krueger, 1997b) Species/strain: rat/Wistar Number/sex of animals: 5/sex Observation period: 14 days Method of administration: the undiluted notified chemical was given dermally for 24 hours under a semi-occlusive dressing Clinical observations: moderate to severe dermal irritation was observed in animals Mortality: none Morphological findings: none Test method: according to OECD Guidelines (Organisation for Economic Co-operation and Development, 1995- 1996) LD50: > 2 000 mg.kg-1 Result: the notified chemical was of low acute dermal toxicity in rats Skin Irritation (Krueger, 1997c) Species/strain: rabbit/White Russian Number/sex of animals: 3 females Observation period: 14 days Method of administration: a single application to the shorn intact skin under a semi-occlusive dressing for 4 hours
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