Monitoring Criteria and Scores RAT – General criteria 0 1 2 Activity i.e. Normal mobile and Somewhat and/or Will only move if – – movement around active intermittent stillness approached or reluctant to the cage as compared to move when touched. others Moderately reduced activity, Bright, Alert, dull, lethargic Responsive (BAR) Body Posture Normal Somewhat and/or Moderate/continuous intermittent hunched hunching and still appearance Gait Normal Somewhat and/or Moderate/continuous intermittent lameness lameness or other gait or other gait abnormality abnormality Social Behaviour Normal Somewhat or Completely separate or intermittently isolated from others (only relevant for separate from others group housed animals) Coat quality/Skin Normal. Coat flat and Somewhat ruffled or Moderately ruffled or condition glossy, showing unkempt or mild moderate piloerection evidence of normal piloerection. consistent with failure to grooming behaviour Somewhat scaly, groom. Moderate scale and scurfy or reddened or scurf, scratches or discolouration of moderate discolouration of skin. skin. Body Condition Animal is NA Animal is under conditioned. Segmentation (see diagram below) Vertebrae and dorsal of vertebral column evident. pelvis not prominent; Dorsal pelvic bones readily palpable with slight palpable. pressure. (see diagram BC 2) (see diagram BC 3) Facial Expression Normal Slight or intermittent Moderate narrowing of the narrowing of the eyes and/or flattening of (see diagram below) eyes and/or the ears. (as per diagram) flattening of the ears. (as per diagram) presenting signs/symptoms Slight or intermittent Moderate or consistent or or possible deviation definite deviation from Although the most relevant monitoring from normal for this normal but not marked, for criteria have been selected, if a sign. this sign. circumstance arises where there are additional presenting signs or behaviours, these must be acknowledged, scored, recorded and reported to the AWO as an adverse event.
Monitoring Criteria and Scores – RAT General criteria 0 1 2 Activity – i.e. movement around the cage Bright, Alert, Responsive (BAR) Normal – mobile and active Somewhat and/or intermittent stillness as compared to others Will only move if approached or reluctant to move when touched. Moderately reduced activity, dull, lethargic Body Posture Normal Somewhat and/or intermittent hunched appearance Moderate/continuous hunching and still Gait Normal Somewhat and/or intermittent lameness or other gait abnormality Moderate/continuous lameness or other gait abnormality Social Behaviour (only relevant for group housed animals) Normal Somewhat or intermittently separate from others Completely separate or isolated from others Coat quality/Skin condition Normal. Coat flat and glossy, showing evidence of normal grooming behaviour Somewhat ruffled or unkempt or mild piloerection. Somewhat scaly, scurfy or reddened or discolouration of skin. Moderately ruffled or moderate piloerection consistent with failure to groom. Moderate scale and scurf, scratches or moderate discolouration of skin. Body Condition (see diagram below) Animal is Vertebrae and dorsal pelvis not prominent; palpable with slight pressure. (see diagram BC 3) NA Animal is under conditioned. Segmentation of vertebral column evident. Dorsal pelvic bones readily palpable. (see diagram BC 2) Facial Expression (see diagram below) Normal Slight or intermittent narrowing of the eyes and/or flattening of the ears. (as per diagram) Moderate narrowing of the eyes and/or flattening of the ears. (as per diagram) presenting signs/symptoms Although the most relevant monitoring criteria have been selected, if a circumstance arises where there are additional presenting signs or behaviours, these must be acknowledged, scored, recorded and reported to the AWO as an adverse event. Slight or intermittent or possible deviation from normal for this sign. Moderate or consistent or definite deviation from normal but not marked, for this sign.
Monitoring-Criteria-RAT.docx