PART 4 OF EVIDENCE –SUMMARY Provide an overview of all key journal articles or research published in the public domain related to the proposed service that is for your application (limiting these to the English language only). Please do not attach full text articles, this is just intended to be a summary. Type of Title of journal article or research Short description of research (max 50 Website link to journal article or Date of study project (including any identifier or words)** research (if available) design* study lead if relevant) * Studies on Assessment of Patients with Small Bowel Crohn’s Disease 1. Retrospective Small Bowel (SB) Capsule Endoscopy The study cohort included consecutive 2015 (CE) in the Management of Established 187 patients with established SB CD who Crohn’s Disease: Clinical Impact, underwent Video Capsule Endoscopy Safety, and Correlation with (VCE) in 4 tertiary referral centres from study. Inflammatory Biomarkers January 2008 to October 2013. et al. 2. Prospective A prospective 52 week mucosal 108 capsule procedures were performed 2014 cohort study. healing assessment of bowel on 43 patients. Based on the Capsule Crohn's disease as detected by capsule Endoscopy Crohn's Disease Activity Index endoscopy. (CECDAI), 39 (90%) demonstrated active small bowel CD at baseline with 28 (65%) Hall et al. undergoing 52 week assessment. 3. Sub-study of a Sequential capsule endoscopy of the Consecutive patients with known 2014 prospective, bowel for follow-up of patients moderately active CD were prospectively randomized, with known Crohn's disease. recruited. A control group of 178 non-CD double blind patients was used for comparisons. Niv et al. CD patients were recruited and 19 controlled met the inclusion criteria. A total of 43 CE study. studies were performed over the time.
PART 4 –SUMMARY OF EVIDENCE Provide an overview of all key journal articles or research published in the public domain related to the proposed service that is for your application (limiting these to the English language only). Please do not attach full text articles, this is just intended to be a summary. Type of study design* Title of journal article or research project (including any identifier or study lead if relevant) Short description of research (max 50 words)** Website link to journal article or research (if available) Date of Studies on Assessment of Patients with Small Bowel Crohn’s Disease 1. study. Small Bowel (SB) Capsule Endoscopy (CE) in the Management of Established Crohn’s Disease: Clinical Impact, Safety, and Correlation with Inflammatory Biomarkers et al. The study cohort included consecutive 187 patients with established SB CD who underwent Video Capsule Endoscopy (VCE) in 4 tertiary referral centres from January 2008 to October 2013. 2015 2. Prospective cohort study. A prospective 52 week mucosal healing assessment of bowel Crohn's disease as detected by capsule endoscopy. Hall et al. 108 capsule procedures were performed on 43 patients. Based on the Capsule Endoscopy Crohn's Disease Activity Index (CECDAI), 39 (90%) demonstrated active small bowel CD at baseline with 28 (65%) undergoing 52 week assessment. 2014 3. Sub-study of a prospective, randomized, double blind study. Sequential capsule endoscopy of the bowel for follow-up of patients with known Crohn's disease. Niv et al. Consecutive patients with known moderately active CD were prospectively recruited. A control group of 178 non-CD patients was used for comparisons. CD patients were recruited and 19 met the inclusion criteria. A total of 43 CE studies were performed over the time. 2014 Retrospective controlled *
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