None Mortality: Hunched posture, piloerection, dyspnea; symptoms resolved Clinical observations: within 5 days. No deviations from normal morphology were observed. Morphological findings: None Comment: > 2000mg/kg LD50: The notified chemical was of very low oral toxicity in Result: rats. 9.1.2 Dermal Toxicity (Hartmann, 1991b) Rats, Tif:RAIf Species/strain: 5 males, 5 females Number/sex of animals: 14 days Observation period: Test substance applied to shaved intact skin under Method of administration: semiocclusive dressing. OECD TG 402 Test method: None Mortality: Piloerection; symptoms resolved within 2 days. Clinical observations: No deviations from normal morphology were observed. Morphological findings: No assessments of skin irritation were provided. Comment: > 2000mg/kg LD50: The notified chemical was of low dermal toxicity in rats. Result: Inhalation toxicity No information was provided. 9.1.4 Skin Irritation (Hagemann, 1991a) Rabbits, New Zealand White Species/strain: 3 Number/sex of animals:
Mortality: None Clinical observations: Hunched posture, piloerection, dyspnea; symptoms resolved within 5 days. Morphological findings: No deviations from normal morphology were observed. Comment: None LD50: > 2000mg/kg Result: The notified chemical was of very low oral toxicity in rats. 9.1.2 Dermal Toxicity (Hartmann, 1991b) Species/strain: Rats, Tif:RAIf Number/sex of animals: 5 males, 5 females Observation period: 14 days Method of administration: Test substance applied to shaved intact skin under semiocclusive dressing. Test method: OECD TG 402 Mortality: None Clinical observations: Piloerection; symptoms resolved within 2 days. Morphological findings: No deviations from normal morphology were observed. Comment: No assessments of skin irritation were provided. LD50: > 2000mg/kg Result: The notified chemical was of low dermal toxicity in rats. Inhalation toxicity No information was provided. 9.1.4 Skin Irritation (Hagemann, 1991a) Species/strain: Rabbits, New Zealand White Number/sex of animals: 3
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