Pentasa® Mesalazine Pentasa® Mesalazine Enema: Enema (1g/100ml) One enema (1g/100ml) administered at bedtime Or Mesalazine suppositories 1g Available as: Salofalk® 1g Dose: Acute mild to moderate suppositories ulcerative proctitis, one choice) Salofalk 1g suppository once daily inserted into the rectum Or Pentasa® 1g Dose: acute attack of proctitis, suppositories 1g daily for 2-4 weeks Oral Treatment 1st choice Oral mesalazine Doses: Available as: Octasa® M/R tablets Octasa® M/R tablets 400mg, 400mg, 800mg 800mg: ulcerative colitis, acute attack, 2.4-4.8g once daily or in divided doses (doses over 2.4g daily in divided doses only) Pentasa® M/R tablets: Pentasa® M/R tablets treatment, up to 4g daily once 500mg, 1g; sachets 1g, daily or in divided doses 2g, 4g
Pentasa® Mesalazine Enema (1g/100ml) Pentasa® Mesalazine Enema: One enema (1g/100ml) administered at bedtime Or Mesalazine suppositories 1g Available as: Salofalk® 1g suppositories choice) Dose: Acute mild to moderate ulcerative proctitis, one Salofalk 1g suppository once daily inserted into the rectum Or Pentasa® 1g suppositories Dose: acute attack of proctitis, 1g daily for 2-4 weeks Oral Treatment 1st choice Oral mesalazine Available as: Octasa® M/R tablets 400mg, 800mg Pentasa® M/R tablets 500mg, 1g; sachets 1g, 2g, 4g Doses: Octasa® M/R tablets 400mg, 800mg: ulcerative colitis, acute attack, 2.4-4.8g once daily or in divided doses (doses over 2.4g daily in divided doses only) Pentasa® M/R tablets: treatment, up to 4g daily once daily or in divided doses
NI%20Formulary%20Chapter%201%20GI%20-%20draft%20for%20consultation.docx