Gluten enteropathy -> circulatinG IgA complexes containing transglutaminase, lodge in —Aetiology: skin And cause inflammation Coeliac antibodies +ve e.g. antiendomysial —Ix: Gluten free diet life long. Dapsone. —Tx: Erythema nodosum. Nodular, red, raised, tender, not itchy, ill-defined, typically shin. Due to panniculitis = fat inflammation. —Associations: TB, post-streptococcus —Infections: OCP, antibiotics. —Drugs: SLE, sarcoidosis, IBD —Systemic: & idiopathic —Pregnancy
—Aetiology: Gluten enteropathy -> circulatinG IgA complexes containing transglutaminase, lodge in skin And cause inflammation —Ix: Coeliac antibodies +ve e.g. antiendomysial —Tx: Gluten free diet life long. Dapsone. Erythema nodosum. Nodular, red, raised, tender, not itchy, ill-defined, typically shin. Due to panniculitis = fat inflammation. —Associations: —Infections: TB, post-streptococcus —Drugs: OCP, antibiotics. —Systemic: SLE, sarcoidosis, IBD —Pregnancy & idiopathic