135,441 122,583 111,000 100,561 82,656 68,068 61,814 42,231 29,059 1.50% 20,132 164,781 149,137 135,045 122,345 100,561 82,813 75,204 51,380 35,353 2.50% 24,494 200,095 181,099 163,987 148,565 122,112 100,561 91,321 62,391 42,930 3.50% 29,743 220,342 199,423 180,580 163,597 134,468 110,736 100,561 68,704 47,274 4.00% 32,752 322,513 291,895 264,314 239,457 196,820 162,084 147,191 100,561 69,195 6.00% 47,940 468,711 424,213 384,130 348,004 286,041 235,558 213,914 146,146 100,561 8.00% 69,671 676,525 612,298 554,442 502,300 412,864 339,998 308,757 210,944 145,147 10.00% 100,561 Healthcare payer perspective From the perspective of the healthcare payer only, increasing or decreasing frequency of CI or HA replacements had no impact on the ICER, as all costs related to these events were borne by the families of children implanted. As expected, favourable ICERs were observed for CI when higher discount rates were applied for costs than QALYs. Duration between replacements (HAs)
1.50% 135,441 122,583 111,000 100,561 82,656 68,068 61,814 42,231 29,059 20,132 2.50% 164,781 149,137 135,045 122,345 100,561 82,813 75,204 51,380 35,353 24,494 3.50% 200,095 181,099 163,987 148,565 122,112 100,561 91,321 62,391 42,930 29,743 4.00% 220,342 199,423 180,580 163,597 134,468 110,736 100,561 68,704 47,274 32,752 6.00% 322,513 291,895 264,314 239,457 196,820 162,084 147,191 100,561 69,195 47,940 8.00% 468,711 424,213 384,130 348,004 286,041 235,558 213,914 146,146 100,561 69,671 10.00% 676,525 612,298 554,442 502,300 412,864 339,998 308,757 210,944 145,147 100,561 Healthcare payer perspective From the perspective of the healthcare payer only, increasing or decreasing frequency of CI or HA replacements had no impact on the ICER, as all costs related to these events were borne by the families of children implanted. As expected, favourable ICERs were observed for CI when higher discount rates were applied for costs than QALYs. Duration between replacements (HAs)