Table ES. Sensitivity and specificity estimates for MRI, CT and X-ray in patients with LBP Suspected Type Study ID, Quality Study type Source Sensit. (%) Specif (%) AUROC LR+ LR- DOR indication a (number of included studies) Lumbar disc CT Moranjkic (2011), 1 study, Study 1 92.3 85.7 0.624 N/A N/A N/A herniation Fair (direct comparison with MRI) Van Rijn (2012), SR (pooled Pooled 77 74 N/A 2.94 0.31 9.61 Good analysis of 6 estimates studies) Jarvik and Deyo SR (2 direct Study 1 88-94 57-64 0.85-0.86 2.1-6.9d 0.11-0.54d N/A (2002), Poor b comparative Study 2 60 86 N/A N/A N/A N/A studies) MRI Moranjkic (2011), 1 study Study 1 91.6 66.7 0.875 N/A N/A N/A Fair (direct comparison with CT) Wassenaar (2012), SR (pooled Pooled 75 77 –c 3.3 0.33 10.12 Fair analysis of 5 estimates studies) Jarvik and Deyo SR (2 direct Study 1 89-100 43-57 0.81-0.84 1.1-33d 0-0.93d N/A (2002), Poor b comparative Study 2 64 87 N/A 1.1-33d 0-0.93d N/A studies) LDH with nerve MRI Wassenaar (2012), SR (2 Study 1 81 100 N/A N/A N/A N/A root Fair studies) Study 2 92 52 N/A N/A N/A N/A compression Spinal stenosis CT Jarvik and Deyo SR (13 Range 70-100 80-96 N/A N/A N/A N/A
Table ES. Sensitivity and specificity estimates for MRI, CT and X-ray in patients with LBP Suspected indication Type Study ID, Quality a Study type (number of included studies) Source Sensit. (%) Specif (%) AUROC LR+ LR- DOR Lumbar disc herniation CT Moranjkic (2011), Fair 1 study, (direct comparison with MRI) Study 1 92.3 85.7 0.624 N/A N/A N/A Van Rijn (2012), Good SR (pooled analysis of 6 studies) Pooled estimates 77 74 N/A 2.94 0.31 9.61 Jarvik and Deyo (2002), Poor b SR (2 direct comparative studies) Study 1 88-94 57-64 0.85-0.86 2.1-6.9d 0.11-0.54d N/A Study 2 60 86 N/A N/A N/A N/A MRI Moranjkic (2011), Fair 1 study (direct comparison with CT) Study 1 91.6 66.7 0.875 N/A N/A N/A Wassenaar (2012), Fair SR (pooled analysis of 5 studies) Pooled estimates 75 77 –c 3.3 0.33 10.12 Jarvik and Deyo (2002), Poor b SR (2 direct comparative studies) Study 1 89-100 43-57 0.81-0.84 1.1-33d 0-0.93d N/A Study 2 64 87 N/A 1.1-33d 0-0.93d N/A LDH with nerve root compression MRI Wassenaar (2012), Fair SR (2 studies) Study 1 81 100 N/A N/A N/A N/A Study 2 92 52 N/A N/A N/A N/A Spinal stenosis CT Jarvik and Deyo SR (13 Range 70-100 80-96 N/A N/A N/A N/A