SUMMARY The following details will be published in the NICNAS Chemical Gazette: ASSESSMENT APPLICANT(S) CHEMICAL OR HAZARDOUS INTRODUCTION USE REFERENCE TRADE NAME SUBSTANCE VOLUME LTD/1509 Estee Lauder Pty 2-Butenedioic acid Yes Component of cosmetic ≤ 1 tonne per Ltd (2E)-, annum products esters (INCI Name: Di-C12-15 Alkyl Fumarate) CONCLUSIONS AND REGULATORY OBLIGATIONS Hazard classification Based on the available information, the notified chemical is recommended for hazard classification according to the as adopted for Globally Harmonised System for the Classification and Labelling of Chemicals (GHS), industrial chemicals in Australia. The recommended hazard classification is presented in the following table. Hazard classification Hazard statement Skin Sensitisation (Category 1) H317 May cause an allergic skin reaction – Based on the available information, the notified chemical is recommended for hazard classification according to the (NOHSC, 2004), with the following risk phrase(s): Approved Criteria for Classifying Hazardous Substances R43: May Cause sensitisation by skin contact Human health risk assessment Under the conditions of the occupational settings described, the notified chemical is not considered to pose an unreasonable risk to the health of workers. When used at 10% in body lotion, 6% in other leave-on cosmetic products and 10% in rinse-off cosmetic ≤ ≤ ≤ products, the notified chemical is not considered to pose an unreasonable risk to public health. Environmental risk assessment On the basis of the reported use pattern, the notified chemical is not considered to pose an unreasonable risk to the environment. Recommendations Hazard Classification and Labelling The notified chemical should be classified as follows: Skin Sensitisation (Category 1): H317 May cause an allergic skin reaction – The following should be used for products/mixtures containing the notified chemical: H317 Conc. ≥ 1%: The Delegate (and/or the Advisory Committee on Chemicals Scheduling) should consider the notified chemical for listing on the SUSMP. Occupational Health and Safety If beauty care professionals are frequently applying cosmetic products containing the notified chemical to clients, employers should implement the following safe work practices to minimise occupational exposure of workers to the notified chemical: Avoid contact with skin
SUMMARY The following details will be published in the NICNAS Chemical Gazette: ASSESSMENT REFERENCE APPLICANT(S) CHEMICAL OR TRADE NAME HAZARDOUS SUBSTANCE INTRODUCTION VOLUME USE LTD/1509 Estee Lauder Pty Ltd 2-Butenedioic acid (2E)-, esters (INCI Name: Di-C12-15 Alkyl Fumarate) Yes ≤ 1 tonne per annum Component of cosmetic products CONCLUSIONS AND REGULATORY OBLIGATIONS Hazard classification Based on the available information, the notified chemical is recommended for hazard classification according to the Globally Harmonised System for the Classification and Labelling of Chemicals (GHS), as adopted for industrial chemicals in Australia. The recommended hazard classification is presented in the following table. Hazard classification Hazard statement Skin Sensitisation (Category 1) H317 – May cause an allergic skin reaction Based on the available information, the notified chemical is recommended for hazard classification according to the Approved Criteria for Classifying Hazardous Substances (NOHSC, 2004), with the following risk phrase(s): R43: May Cause sensitisation by skin contact Human health risk assessment Under the conditions of the occupational settings described, the notified chemical is not considered to pose an unreasonable risk to the health of workers. When used at ≤ 10% in body lotion, ≤ 6% in other leave-on cosmetic products and ≤ 10% in rinse-off cosmetic products, the notified chemical is not considered to pose an unreasonable risk to public health. Environmental risk assessment On the basis of the reported use pattern, the notified chemical is not considered to pose an unreasonable risk to the environment. Recommendations Hazard Classification and Labelling The notified chemical should be classified as follows: Skin Sensitisation (Category 1): H317 – May cause an allergic skin reaction The following should be used for products/mixtures containing the notified chemical: Conc. ≥ 1%: H317 The Delegate (and/or the Advisory Committee on Chemicals Scheduling) should consider the notified chemical for listing on the SUSMP. Occupational Health and Safety If beauty care professionals are frequently applying cosmetic products containing the notified chemical to clients, employers should implement the following safe work practices to minimise occupational exposure of workers to the notified chemical: Avoid contact with skin