Anticholinergics No No studies comparing Although evidence of anticholinergic to benefit over placebo is placebo. lacking, anticholinergics can be tried on an Weak evidence that individual patient basis. glycopyrronium may be superior to hyoscine Glycopyrronium may be hydrobromide (76) more effective than other anti-cholinergics. No difference between atropine, hyoscine hydrobromide or hyoscine butylbromide (78) Octreotide No No evidence that Although there is no octreotide is better than evidence that octreotide is placebo or better than any other anticholinergics (79) medcation for management of secretions, it could be tried if anti-cholinergics fail.
Anticholinergics No No studies comparing anticholinergic to placebo. Weak evidence that glycopyrronium may be superior to hyoscine hydrobromide (76) No difference between atropine, hyoscine hydrobromide or hyoscine butylbromide (78) Although evidence of benefit over placebo is lacking, anticholinergics can be tried on an individual patient basis. Glycopyrronium may be more effective than other anti-cholinergics. Octreotide No No evidence that octreotide is better than placebo or anticholinergics (79) Although there is no evidence that octreotide is better than any other medcation for management of secretions, it could be tried if anti-cholinergics fail.