accuracy secondary studies) spinal care setting published full infection/inflammation reports with spondylolisthesis, sufficient data spondylolysis, spinal to construct a fractures two-by-two AS table disc displacement comparison osteoporotic fractures with a other degenerative disc reference diseases standard Sidiropoulos search to Aug Guideline X-ray sensitivity Patients with ankylosing Not clear Not mentioned No MRI 2008 2006 included 467 specificity spondylitis and evident or CT papers (CPG) appropriate positive LR suspected sacroiliitis covering study Poor quality negative diagnosis, population LR treatment relevant and outcomes monitoring with data on Setting not selected outcome specified measures excluded case reports, studies with TNF-α antagonists, animal studies, narrative
accuracy published full reports with sufficient data to construct a two-by-two table comparison with a reference standard secondary care setting spinal infection/inflammation spondylolisthesis, spondylolysis, spinal fractures AS disc displacement osteoporotic fractures other degenerative disc diseases studies) Sidiropoulos 2008 (CPG) Poor quality search to Aug 2006 appropriate study population relevant outcomes with data on selected outcome measures excluded case reports, studies with TNF-α antagonists, animal studies, narrative Guideline included 467 papers covering diagnosis, treatment and monitoring Setting not specified Patients with ankylosing spondylitis and evident or suspected sacroiliitis X-ray MRI CT Not clear Not mentioned sensitivity specificity positive LR negative LR No