Table 034 Characteristics of included systematic reviews of diagnostic accuracy of imaging for low back pain Literature Number of search date and studies, Ref ID and Intervention Reference Outcome Study eligibility Number of Patient population Comparators Meta-analysis Qualitya index test standard measures patients and Setting N/A van Rijn search to Dec 7 Adult patients with LBP CT surgical sensitivity Yes (6 out of 2012 2009 observational or sciatica suspected to findings (6 the 7 studies) specificity studies be caused by specific studies) Good prospective or positive pathology: quality retrospective N=498 discs expert panel LR cohort or opinion (1 All identified radicular syndrome negative case-control study) studies were spinal stenosis LR studies in the diagnostic spinal tumours assessing secondary work-up (0 spinal diagnostic care setting studies) infection/inflammation accuracy MRI (0 spondylolisthesis, published full studies) spondylolysis, spinal reports with fractures sufficient data AS to construct a disc displacement two-by-two osteoporotic fractures table other degenerative disc comparison diseases with a reference standard Wassenaar 8 surgical sensitivity search to Dec Adult patients with LBP or MRI N/A Yes (5 out of the 2012 observational findings (7 2009 specificity sciatica suspected to be 8 studies) studies studies) Fair quality positive LR prospective or caused by lumbar N=467 expert panel negative retrospective spinal pathology: patients consensus (1 LR cohort or radicular syndrome study) All identified control studies spinal stenosis studies were diagnostic assessing spinal tumours in the work-up (0 diagnostic
Table 034 Characteristics of included systematic reviews of diagnostic accuracy of imaging for low back pain Ref ID and Qualitya Literature search date and Study eligibility Number of studies, Number of patients and Setting Patient population index test Comparators Reference standard Outcome measures Meta-analysis van Rijn 2012 Good quality search to Dec 2009 prospective or retrospective cohort or case-control studies assessing diagnostic accuracy published full reports with sufficient data to construct a two-by-two table comparison with a reference standard 7 observational studies N=498 discs All identified studies were in the secondary care setting Adult patients with LBP or sciatica suspected to be caused by specific pathology: radicular syndrome spinal stenosis spinal tumours spinal infection/inflammation spondylolisthesis, spondylolysis, spinal fractures AS disc displacement osteoporotic fractures other degenerative disc diseases CT N/A surgical findings (6 studies) expert panel opinion (1 study) diagnostic work-up (0 studies) MRI (0 studies) sensitivity specificity positive LR negative LR Yes (6 out of the 7 studies) Wassenaar 2012 Fair quality search to Dec 2009 prospective or retrospective cohort or studies assessing diagnostic 8 observational studies N=467 patients All identified studies were in the Adult patients with LBP or sciatica suspected to be caused by lumbar spinal pathology: radicular syndrome spinal stenosis spinal tumours MRI N/A surgical findings (7 studies) expert panel consensus (1 study) diagnostic work-up (0 sensitivity specificity positive LR negative LR Yes (5 out of the 8 studies) control Intervention