generated -advanced non–small-cell lung cancer sensorineural hearing loss, and paediatric neurodevelopmental disorders of unknown genetic aetiology. Hydatidiform Moles Type of study Title of journal Short description of Website link to Date of design* article or research research (max 50 journal article or project (including words)** research (if any trial identifier available) or study lead if relevant) 1. Study of Furtado LV, Paxton A study of molecular 2 Jan diagnostic CN, Jama MA, et al: genotyping for 2013 accuracy Diagnostic utility of diagnosing and microsatellite classifying genotyping for hydatidiform mole to molar pregnancy distinguish differences testing. Arch Pathol in risk for persistent Lab Med 137:55-63, gestational 2013 trophoblastic disease. Data on 102 cases were presented; 48 were classified as hydatidiform mole (31 complete hydatidiform mole; 17 partial hydatidiform mole) demonstrating the utility of microsatellite genotyping for accurate classification of hydatidiform mole. 2. Study of LeGallo RD, Stelow A study of HER2 FISH 2008 diagnostic EB, Ramirez NC, for the diagnosis and accuracy Atkins KA. classification of 54 Diagnosis of cases of hydatidiform hydatidiform moles moles (HM) using p57 demonstrating the utility of HER2 FISH and HER2 and IHC for p57 in the fluorescent in situ evaluation of HM, hybridization. Am J especially when Clin Pathol. triploid content is
generated -advanced non–small-cell lung cancer sensorineural hearing loss, and paediatric neurodevelopmental disorders of unknown genetic aetiology. Hydatidiform Moles Type of study design* Title of journal article or research project (including any trial identifier or study lead if relevant) Short description of research (max 50 words)** Website link to journal article or research (if available) Date of 1. Study of diagnostic accuracy Furtado LV, Paxton CN, Jama MA, et al: Diagnostic utility of microsatellite genotyping for molar pregnancy testing. Arch Pathol Lab Med 137:55-63, 2013 A study of molecular genotyping for diagnosing and classifying hydatidiform mole to distinguish differences in risk for persistent gestational trophoblastic disease. Data on 102 cases were presented; 48 were classified as hydatidiform mole (31 complete hydatidiform mole; 17 partial hydatidiform mole) demonstrating the utility of microsatellite genotyping for accurate classification of hydatidiform mole. 2 Jan 2013 2. Study of diagnostic accuracy LeGallo RD, Stelow EB, Ramirez NC, Atkins KA. Diagnosis of hydatidiform moles using p57 and HER2 fluorescent in situ hybridization. Am J Clin Pathol. A study of HER2 FISH for the diagnosis and classification of 54 cases of hydatidiform moles (HM) demonstrating the utility of HER2 FISH and IHC for p57 in the evaluation of HM, especially when triploid content is 2008