diagnosed with non-TB mycobacterial infection All TB ascertained by 2,950 14,274 1.18 Leegaard et al Denmark January, Northern Danish Cases: first time DM ascertained by in- or 7 Matched by: age (±5 ICD–8: 010–019; ICD–10: (0.96–1.45) (2011) [] population hospital contact outpatient hospital contact years), sex, country A15–A19 codes. A subset with principal involving diabetes, any use of origin, & place & microbiologically 2008 diagnosis of TB of oral anti-diabetes drugs length of residence confirmed TB obtained from or insulin, at least one visit in Denmark (±1 DNRP who lived in to a chiropodist for year) Northern Denmark diabetes foot care, at least Adjusted for: age, for ≥6 months since five glucose-related sex, country of the TB diagnosis services in general practice origin, place & date in 1 year, or at least two length of residence glucose-related services in Denmark, Controls: TB-free each year during 5 comorbidities individuals from subsequent years. (myocardial Danish civilian infarction, registration system Patients under 30 on congestive heart therapy = Type 1DM, rest failure, peripheral Type 2DM. vascular disease, HbA1c where available for CVD, dementia, a subset of controls and COPD, connective cases. tissue disease , ulcer 2.59 disease, mild liver (0.44–15.29) disease, hemiplegia, moderate to severe Type 1 DM renal disease, any 1.17 tumor, leukemia, (0.95–1.44) lymphoma, metastatic solid Type 2 DM tumor, & HIV/AIDS), alcoholism-related disorders, marital status, number of children <15 years, & degree of urbanization
diagnosed with non-TB mycobacterial infection Leegaard et al (2011) [] Denmark January, 2008 Northern Danish population Cases: first time hospital contact with principal diagnosis of TB obtained from DNRP who lived in Northern Denmark for ≥6 months since the TB diagnosis date Controls: TB-free individuals from Danish civilian registration system DM ascertained by in- or outpatient hospital contact involving diabetes, any use of oral anti-diabetes drugs or insulin, at least one visit to a chiropodist for diabetes foot care, at least five glucose-related services in general practice in 1 year, or at least two glucose-related services each year during 5 subsequent years. Patients under 30 on therapy = Type 1DM, rest Type 2DM. HbA1c where available for a subset of controls and cases. Type 1 DM Type 2 DM All TB ascertained by ICD–8: 010–019; ICD–10: A15–A19 codes. A subset microbiologically confirmed TB 2,950 14,274 1.18 (0.96–1.45) 2.59 (0.44–15.29) 1.17 (0.95–1.44) 7 Matched by: age (±5 years), sex, country of origin, & place & length of residence in Denmark (±1 year) Adjusted for: age, sex, country of origin, place & length of residence in Denmark, comorbidities (myocardial infarction, congestive heart failure, peripheral vascular disease, CVD, dementia, COPD, connective tissue disease , ulcer disease, mild liver disease, hemiplegia, moderate to severe renal disease, any tumor, leukemia, lymphoma, metastatic solid tumor, & HIV/AIDS), alcoholism-related disorders, marital status, number of children <15 years, & degree of urbanization