Supplementary Table 3. Characteristics of T-ALL cell lines used for xenograft experiments. Molecular-genetic Mutations subtypes Cell line Patient at: Age Sex activation) fusion fusion deletion HOXA deletion deletion deletion in deletion deletion deletion amplification deletion HOX11 HOX11L NOXA9 SIL-TAL1 MLLT3 MTAP MYB Immuno-phenotype CASP8AP2 CDKN2A CDKN2B NUP214-ABL1 SIL-TAL PTEN SET-NUP214 LEF (results Y Y * LOUCY Diagnosis (no remission achieved) 1 1 1 38 female ALL-SIL Relapse 2 2 Y Y 17 male 8
Supplementary Table 3. Characteristics of T-ALL cell lines used for xenograft experiments. Mutations Molecular-genetic subtypes Cell line Patient at: SIL-TAL1 HOX11 HOX11L NOXA9 Age Sex Immuno-phenotype SIL-TAL deletion LEF deletion CASP8AP2 deletion MLLT3 deletion MTAP deletion CDKN2A deletion CDKN2B deletion PTEN deletion MYB amplification NUP214-ABL1 fusion SET-NUP214 fusion (results in HOXA activation) LOUCY Diagnosis (no remission achieved) 1 1 1 Y Y 38 female * ALL-SIL Relapse 2 2 Y Y 17 male 8