Stampfer MJ et 33 volunteers Randomised to aspirin 325mg, one of Bleeding times, platelet aggregation Plain and EC aspirin were equally efficacious Short study time of 7 days. Alternate day al.14 two EC aspirin preparations 325mg, or and TXA2 levels before and after a in prolonging bleeding time, inhibition of dosing used. No indication of actual clinical placebo. Tablets were taken every other single dose, and after seven platelet aggregation and suppression of TXA2. outcomes of participants 1986 day doses RCT
Stampfer MJ et al.14 1986 RCT 33 volunteers Randomised to aspirin 325mg, one of two EC aspirin preparations 325mg, or placebo. Tablets were taken every other day Bleeding times, platelet aggregation and TXA2 levels before and after a single dose, and after seven doses Plain and EC aspirin were equally efficacious in prolonging bleeding time, inhibition of platelet aggregation and suppression of TXA2. Short study time of 7 days. Alternate day dosing used. No indication of actual clinical outcomes of participants