Table 3.2.5. Distributions of characteristics and logistic model results regarding presence of positive non-sentinel nodes (NSNs) Metastasis found in Univariate Multivariate NSN(s)? Characteristic No Yes Crude OR Adjusted OR (N=263) (N=60) (95%CI) (95%CI) N (%) N (%) Age at SNB#*$ 51.7 ± 54.7 ± 1.11 0.224 1.08 0.406 16.9 17.2 Gender Male 157 1 1 Female (79.3) 41(20.7) 0.69 0.217 0.73 0.319 106 (84.8) 19(15.2) Tumor thickness (mm) 79 (82.3) 17 (17.7) 1 1 ≤2.0 110 23 (17.3) 0.97 0.935 0.45 0.061 2.1-4.0 (82.7) 20 (22.2) 0.442 0.376 >4.0 70 (77.8) 1.33 0.68 Ulceration No 149 24(13.9) 1 1 Yes (86.1) 35(26.5) 2.24 0.006 2.06 0.042 97 (73.5) Mitotic rate (mitoses/mm2) ≤5 163 28 (14.7) 1 1 6-10 (85.3) 16 (22.9) 1.73 0.120 1.75 0.137 >10 54 (76.1) 15 (28.3) 0.024 0.092 38 (71.7) 2.30 2.02 Number of 2.1 ± 1.1 1.8 ± 1.0 0.80 0.119 0.79 0.124 sentinel nodes removed # SNB=sentinel node biopsy *Mean ± SD $ Adjusted odds ratio for age in 10 year increments Figure 3.2.5. Survival tree model for sentinel node (SN) positive patients (non-sentinel node = NSN; sentinel node biopsy = SNB).
Table 3.2.5. Distributions of characteristics and logistic model results regarding presence of positive non-sentinel nodes (NSNs) Metastasis found in NSN(s)? Univariate Multivariate Characteristic No (N=263) N (%) Yes (N=60) N (%) Crude OR (95%CI) Adjusted OR (95%CI) Age at SNB#*$ 51.7 ± 16.9 54.7 ± 17.2 1.11 0.224 1.08 0.406 Gender Male Female 157 (79.3) 106 (84.8) 41(20.7) 19(15.2) 1 0.69 0.217 1 0.73 0.319 Tumor thickness (mm) ≤2.0 2.1-4.0 >4.0 79 (82.3) 110 (82.7) 70 (77.8) 17 (17.7) 23 (17.3) 20 (22.2) 1 0.97 1.33 0.935 0.442 1 0.45 0.68 0.061 0.376 Ulceration No Yes 149 (86.1) 97 (73.5) 24(13.9) 35(26.5) 1 2.24 0.006 1 2.06 0.042 Mitotic rate (mitoses/mm2) ≤5 6-10 >10 163 (85.3) 54 (76.1) 38 (71.7) 28 (14.7) 16 (22.9) 15 (28.3) 1 1.73 2.30 0.120 0.024 1 1.75 2.02 0.137 0.092 Number of sentinel nodes removed 2.1 ± 1.1 1.8 ± 1.0 0.80 0.119 0.79 0.124 # SNB=sentinel node biopsy *Mean ± SD $ Adjusted odds ratio for age in 10 year increments Figure 3.2.5. Survival tree model for sentinel node (SN) positive patients (non-sentinel node = NSN; sentinel node biopsy = SNB).