hormone use, randomized treatment assignment, red meat intake, smoking status, total energy intake, vitamin b6 intake Jacobs, 2003 CPS II, 797/ Self-reported FFQ Incidence, Age, sex, BMI, COL00313 Prospective 145 260 and National colorectal calcium supplement, USA Cohort, 5 years Index Multivitamins cancer, vs educational level, ≥16 ≤0 0.71 (0.57-0.89) Age: 30- years, (no details) times/month fibre, physical activity, M/W, saturated fat, vitamin c subgroup of supplement CPS-II cohort 564/ Incidence, colon vs ≥16 ≤0 0.72 (0.55-0.94) cancer, 232/ Incidence, rectal vs ≥16 ≤0 0.69 (0.46-1.04) cancer, times/month Sanjoaquin, OVS, 91/ Cancer registry FFQ Incidence, 2004 Prospective 10 998 Vitamin colorectal Age, sex, alcohol COL01182 Cohort, 17 years supplements (no cancer, 1.00 (0.63-1.59) used vs not used consumption, smoking UK Age: 18-89 details) Ptrend:0.993 habits years, M/W Kato, 1999 New York 150/ Follow-up Incidence, Age, beer COL00436 University 81 questionnaire FFQ colorectal consumption, date of USA Women's Health cancer, enrolment, date of Study, Any subsequent blood, any vs none 0.67 (0.42-1.06) Nested Case vitamin/mineral family history of Control, (no details) specific cancer, Age: 62 years, menopausal status, W occult blood testing,
hormone use, randomized treatment assignment, red meat intake, smoking status, total energy intake, vitamin b6 intake Jacobs, 2003 COL00313 USA CPS II, Prospective Cohort, Age: 30- years, M/W, subgroup of CPS-II cohort 797/ 145 260 5 years Self-reported and National Index FFQ Multivitamins (no details) Incidence, colorectal cancer, ≥16 vs ≤0 times/month 0.71 (0.57-0.89) Age, sex, BMI, calcium supplement, educational level, fibre, physical activity, saturated fat, vitamin c supplement 564/ Incidence, colon cancer, ≥16 vs ≤0 0.72 (0.55-0.94) 232/ Incidence, rectal cancer, ≥16 vs ≤0 times/month 0.69 (0.46-1.04) Sanjoaquin, 2004 COL01182 UK OVS, Prospective Cohort, Age: 18-89 years, M/W 91/ 10 998 17 years Cancer registry FFQ Vitamin supplements (no details) Incidence, colorectal cancer, used vs not used 1.00 (0.63-1.59) Ptrend:0.993 Age, sex, alcohol consumption, smoking habits Kato, 1999 COL00436 USA New York University Women's Health Study, Nested Case Control, Age: 62 years, W 150/ 81 Follow-up questionnaire FFQ Any vitamin/mineral (no details) Incidence, colorectal cancer, any vs none 0.67 (0.42-1.06) Age, beer consumption, date of enrolment, date of subsequent blood, family history of specific cancer, menopausal status, occult blood testing,