Rethinking the role of superhydrophobicity in non-cell-adhesive biomaterial surfaces. Abstract. The potential of superhydrophobic surfaces have gained increased interest in the last decades. In the research field of anti-fouling and anti-coagulation of materials, this phenomenon is of particular interest due to its ability to prevent cell-adhesion in medical devices and implants. Even though publications including the new advanced fabrication methods of superhydrophobic materials are being widely spread, the role of the nanostructured surface remains unclear. Reports reveal contradictive results in the stability of the superhydrophobic state, and the influence on all interfacial factors involved in cell response remain unsure. Elucidating and understanding the underlying technical and physiological mechanisms involved in the utility of superhydrophobic materials is obligate to ensure optimal biocompatibility. To establish an accelerated movement from superhydrophobic fabrication method to medical applications, the reasons behind the conflicting results and theories should be revealed. Only then superhydrophobic surfaces can be transformed from theory to practice.
Rethinking the role of superhydrophobicity in non-cell-adhesive biomaterial surfaces. Abstract. The potential of superhydrophobic surfaces have gained increased interest in the last decades. In the research field of anti-fouling and anti-coagulation of materials, this phenomenon is of particular interest due to its ability to prevent cell-adhesion in medical devices and implants. Even though publications including the new advanced fabrication methods of superhydrophobic materials are being widely spread, the role of the nanostructured surface remains unclear. Reports reveal contradictive results in the stability of the superhydrophobic state, and the influence on all interfacial factors involved in cell response remain unsure. Elucidating and understanding the underlying technical and physiological mechanisms involved in the utility of superhydrophobic materials is obligate to ensure optimal biocompatibility. To establish an accelerated movement from superhydrophobic fabrication method to medical applications, the reasons behind the conflicting results and theories should be revealed. Only then superhydrophobic surfaces can be transformed from theory to practice.