MONITORING REQUIREMENTS Monitoring schedule More frequent monitoring (monthly) is appropriate in patients at higher risk of toxicity. Contact specialist team urgently and consider interruption in treatment if any of the following develop: Whilst absolute values are useful indicators, trends are equally important, and any rapid fall or consistent downward trend in any parameter warrants extra vigilance. This list is not exhaustive; refer to the Summary of Product Characteristics (SMPC) or BNF for further guidance. OTHER WARNING SIGNS Rash or oral ulceration: Check FBC and withhold treatment until results available Abnormal bruising or severe sore throat: Check FBC and withhold treatment until results available This list is not exhaustive; refer to the Summary of Product Characteristics (SMPC) or BNF for further guidance.
MONITORING REQUIREMENTS Monitoring schedule More frequent monitoring (monthly) is appropriate in patients at higher risk of toxicity. Contact specialist team urgently and consider interruption in treatment if any of the following develop: Whilst absolute values are useful indicators, trends are equally important, and any rapid fall or consistent downward trend in any parameter warrants extra vigilance. This list is not exhaustive; refer to the Summary of Product Characteristics (SMPC) or BNF for further guidance. OTHER WARNING SIGNS Rash or oral ulceration: Check FBC and withhold treatment until results available Abnormal bruising or severe sore throat: Check FBC and withhold treatment until results available This list is not exhaustive; refer to the Summary of Product Characteristics (SMPC) or BNF for further guidance.