Supplemental Table 8. Baseline Patient Characteristics Associated With Increased or Decreased Risk of TE Grade 3 ≥ Infection in the First 4 Months Found by Univariate Analysis Requested by Clinical Experts Patients With TE Patients, Variable Grade 3 Odds Ratio (CI) P Value ≥ n (%) Infections, % All patients (analysis set) 1 378 (100) 13.9 Serum 6 466 (33.8) 24.2 3.42 (2.5-4.7) 8.10 × β2-microglobulin ≥ mg/L† 10−15 Serum 3 mg/L 242 (17.6) 4.1 0.23 (0.1-0.4) 7.11 × β2-microglobulin ≤ † 10−8 Creatinine 1.2 mg/dL 445 (32.3) 20.4 2.14 (1.6-2.9) 1.36 × ≥ † 10−6 Lactate dehydrogenase 200 242 (17.6) 24.0 2.38 (1.7-3.4) 1.79 × ≥ U/L† 10−6 Hemoglobin 9 256 (18.6) 22.7 2.18 (1.5-3.1) 1.34 × ≤ g/dL† 10−5 Hemoglobin 11 496 (36.0) 8.3 0.44 (0.3-0.6) 2.43 × ≥ g/dL† 10−6 ISS stage < 2 290 (21.0) 6.6 0.37 (0.2-0.6) 1.17 × 10−5 ECOG PS < 415 (30.1) 8.2 0.46 (0.3-0.7) 2.38 × 1† 10−5 ECOG PS 280 (20.3) 22.5 2.20 (1.6-3.1) 5.97 × ≥ 2† 10−6 Albumin 3 g/dL 285 (20.7) 20.4 1.84 (1.3-2.6) 4.14 × ≤ 10−4 Platelets 100 × 109/L 59 (4.3) 28.8 2.66 (1.5-4.8) 1.67 × ≤ 10−3
Supplemental Table 8. Baseline Patient Characteristics Associated With Increased or Decreased Risk of TE Grade ≥ 3 Infection in the First 4 Months Found by Univariate Analysis Requested by Clinical Experts Variable Patients, n (%) Patients With TE Grade ≥ 3 Infections, % Odds Ratio (CI) P Value All patients (analysis set) 1 378 (100) 13.9 Serum β2-microglobulin ≥ 6 mg/L† 466 (33.8) 24.2 3.42 (2.5-4.7) 8.10 × 10−15 Serum β2-microglobulin ≤ 3 mg/L † 242 (17.6) 4.1 0.23 (0.1-0.4) 7.11 × 10−8 Creatinine ≥ 1.2 mg/dL † 445 (32.3) 20.4 2.14 (1.6-2.9) 1.36 × 10−6 Lactate dehydrogenase ≥ 200 U/L† 242 (17.6) 24.0 2.38 (1.7-3.4) 1.79 × 10−6 Hemoglobin ≤ 9 g/dL† 256 (18.6) 22.7 2.18 (1.5-3.1) 1.34 × 10−5 Hemoglobin ≥ 11 g/dL† 496 (36.0) 8.3 0.44 (0.3-0.6) 2.43 × 10−6 ISS stage < 2 290 (21.0) 6.6 0.37 (0.2-0.6) 1.17 × 10−5 ECOG PS < 1† 415 (30.1) 8.2 0.46 (0.3-0.7) 2.38 × 10−5 ECOG PS ≥ 2† 280 (20.3) 22.5 2.20 (1.6-3.1) 5.97 × 10−6 Albumin ≤ 3 g/dL 285 (20.7) 20.4 1.84 (1.3-2.6) 4.14 × 10−4 Platelets ≤ 100 × 109/L 59 (4.3) 28.8 2.66 (1.5-4.8) 1.67 × 10−3