Grade2 n=17 Grade3 n=1 et al Intra- patient RTOG and 78 Mepitel® /film Breast Moist 0% P<0.001 + 2014 RCT - Modified vs. aqueous desquamation intervention blinding not RISRAS cream 26% control possible Jensen et Single Centre ONS 66 WO1932 ( oil in Breast ONS 0-3 visit 3 (day P=0.059 + al 2011 RCT trial emulsion ) 47 +/- 7) vs. no normalised treatment skin higher in treatment n=14 vs. control n=6 Kirova et al III RCT RTOG 200 Hyaluronic Acid Breast Disappearance 20.4% in + 2011 VAS vs. control of erythema intervention EORTC emollient based arm P=0.46 Colormetric 13% in values control arm failure = n=23 (24.2%) p=0.15 interruption of in treatment intervention arm n=32 (33.7%) in control arm Paterson et Within RISRAS 74 Mepilex®lite Breast ( post RISRAS score Results (p<0.001) 0 al 2012 subjects RCT, dressings vs. mastectomy) showed no blinding aqueous cream improved average RISRAS scores for Mepilex ®lite compared
Grade2 n=17 Grade3 n=1 et al 2014 Intra- patient RCT - blinding not possible RTOG and Modified RISRAS 78 Mepitel® /film vs. aqueous cream Breast Moist desquamation 0% intervention 26% control P<0.001 + Jensen et al 2011 Single Centre RCT ONS 66 WO1932 ( oil in emulsion ) vs. no treatment Breast ONS 0-3 visit 3 (day 47 +/- 7) normalised skin higher in treatment n=14 vs. control n=6 P=0.059 + Kirova et al 2011 III RCT RTOG VAS EORTC 200 Hyaluronic Acid vs. control emollient Breast Disappearance of erythema based Colormetric values failure = interruption of treatment 20.4% in intervention arm 13% in control arm n=23 (24.2%) in intervention arm n=32 (33.7%) in control arm P=0.46 p=0.15 + Paterson et al 2012 Within subjects RCT, no blinding RISRAS 74 Mepilex®lite dressings vs. aqueous cream Breast ( post mastectomy) RISRAS score Results showed improved average RISRAS scores for Mepilex ®lite compared (p<0.001) 0 trial