vitamin b6 Age, sex, 1 023/ alcohol, BMI, Incidence, educational 99 523 0.81 (0.66–0.99) colorectal cancer level, 15 years endoscopy, energy intake, CPS II-Nutrition Superseded by family history of Cohort, Pooling Project Cancer registry Stevens, 2011 colorectal Incidence, colon Prospective vs <422 Kim, 2010 for ≥1224 799 and medical FFQ 0.83 (0.66–1.04) COL40887 cancer, HRT cancer Cohort, mcg/day colon cancer USA use, low-fat records Age: 50-74 dose response dairy products, M/W meta-analysis. non-steriodal Incidence, rectal 219 0.73 (0.47–1.16) drug use, race, cancer red meat, smoking BCDDP 349 Follow-up CPS II 816 Kim, 2010 questionnaires Incidence, vs <240 ≥560 HPFS 456 FFQ 0.87 (0.78-0.98) Pooling Project and medical mcg/day IWHS 799 records NYS 558
vitamin b6 Stevens, 2011 COL40887 USA CPS II-Nutrition Cohort, Prospective Cohort, Age: 50-74 M/W 1 023/ 99 523 15 years Cancer registry and medical records FFQ Incidence, colorectal cancer ≥1224 vs <422 mcg/day 0.81 (0.66–0.99) Age, sex, alcohol, BMI, educational level, endoscopy, energy intake, family history of colorectal cancer, HRT use, low-fat dairy products, non-steriodal drug use, race, red meat, smoking Superseded by Pooling Project Kim, 2010 for colon cancer dose response meta-analysis. 799 Incidence, colon cancer 0.83 (0.66–1.04) 219 Incidence, rectal cancer 0.73 (0.47–1.16) Kim, 2010 Pooling Project BCDDP CPS II HPFS IWHS NYS 349 816 456 799 558 Follow-up questionnaires and medical records FFQ Incidence, ≥560 vs <240 mcg/day 0.87 (0.78-0.98)