Table S1 Use and definition of WoE evaluation in key legislative texts, guidance documents, and opinions of scientific advisory groups Legislative text / guidance document / Reference to weight of evidence, definitions, and key elements Steps scientific opinion of advisory body or included committee Draft Commission Regulation setting out In order to implement those criteria, weight of evidence should be applied considering in scientific criteria for the determination of particular the approach provided for in Regulation (EC) No 1272/2008 of the European (1b) endocrine disrupting properties and amending Parliament and of the Council on the weight of evidence. In addition, the … Annex II to Regulation (EC) 1107/2009. implementation of the criteria should be based on all relevant scientific evidence… (SANTE-2016-12020-REV 2) Draft Annex to the Commission Regulation Note: The elements for health (HH) and non-target organisms are essentially similar. amending Annex II to Regulation (EC) Text which is specific to HH assessment has been highlighted in {cursive brackets and red 1107/2009 by setting out scientific criteria for font} and text specific to non-target organisms has been highlighted with [square brackets the determination of endocrine disrupting and blue font]. properties. (SANTE-2016-12020-REV 2)
Table S1 Use and definition of WoE evaluation in key legislative texts, guidance documents, and opinions of scientific advisory groups Legislative text / guidance document / scientific opinion of advisory body or committee Reference to weight of evidence, definitions, and key elements Steps included Draft Commission Regulation setting out scientific criteria for the determination of endocrine disrupting properties and amending Annex II to Regulation (EC) 1107/2009. (SANTE-2016-12020-REV 2) In order to implement those criteria, weight of evidence should be applied considering in particular the approach provided for in Regulation (EC) No 1272/2008 of the European Parliament and of the Council on the weight of evidence. … In addition, the implementation of the criteria should be based on all relevant scientific evidence… (1b) Draft Annex to the Commission Regulation amending Annex II to Regulation (EC) 1107/2009 by setting out scientific criteria for the determination of endocrine disrupting properties. (SANTE-2016-12020-REV 2) Note: The elements for health (HH) and non-target organisms are essentially similar. Text which is specific to HH assessment has been highlighted in {cursive brackets and red font} and text specific to non-target organisms has been highlighted with [square brackets and blue font].