Age: 35-101 height, category. years, of 102/ Women 42.3 vs 10.7 g 0.79 (0.49-1.28) M/W smoking, physical activity 733/ Incidence, Age, alcohol 61 433 vs 0-1.9 ≥4 colorectal 1.22 (0.98-1.53) consumption, Distribution of 855 585 servings/week cancer, BMI, calcium, person-years by SMC, exposure educational Prospective category. Incidence, Larsson, 2005 energy intake, vs 0-1.9 ≥4 Cohort, of 234/ proximal colon 1.10 (0.74-1.64) COL01849 Cancer registry Questionnaire fish, folate, servings/week Age: 40-75 exposure cancer, Sweden fruits, poultry, categories. years, saturated fat, Conversion from Incidence, rectal vs 0-1.9 W ≥4 230/ 1.08 (0.72-1.62) vegetables, servings/week to cancer, servings/week whole-grain g/day. Incidence, distal vs 0-1.9 foods ≥4 155/ 1.99 (1.26-3.14) colon cancer, servings/week Incidence, 1 329/ Age, sex, colorectal per 100 g/day 1.21 (1.02-1.43) 478 040 alcohol cancer, 2 279 075 consumption, vs person-years ≥80 ≤10 EPIC, body weight, 1.17 (0.92-1.49) Continuous g/day Prospective centre location, 2005 results were Cohort, energy from fat per 100 g/day 1.20 (0.96-1.48) COL01698 Cancer registry Questionnaire directly used in Age: 21-83 Incidence, colon sources, energy 855/ Europe dose-response cancer, vs years, from non-fat ≥80 ≤10 1.20 (0.88-1.61) analysis g/day M/W sources, fibre, height, physical per 100 g/day 1.23 (0.94-1.62) activity, Incidence, rectal 474/ smoking status vs cancer, ≥80 ≤10 1.13 (0.74-1.71) g/day
Age: 35-101 years, M/W height, of smoking, physical activity category. 102/ Women 42.3 vs 10.7 g 0.79 (0.49-1.28) Larsson, 2005 COL01849 Sweden SMC, Prospective Cohort, Age: 40-75 years, W 733/ 61 433 855 585 Cancer registry Questionnaire Incidence, colorectal cancer, ≥4 vs 0-1.9 servings/week 1.22 (0.98-1.53) Age, alcohol consumption, BMI, calcium, educational energy intake, fish, folate, fruits, poultry, saturated fat, vegetables, whole-grain foods Distribution of person-years by exposure category. of exposure categories. Conversion from servings/week to g/day. 234/ Incidence, proximal colon cancer, ≥4 vs 0-1.9 servings/week 1.10 (0.74-1.64) 230/ Incidence, rectal cancer, ≥4 vs 0-1.9 servings/week 1.08 (0.72-1.62) 155/ Incidence, distal colon cancer, ≥4 vs 0-1.9 servings/week 1.99 (1.26-3.14) 2005 COL01698 Europe EPIC, Prospective Cohort, Age: 21-83 years, M/W 1 329/ 478 040 2 279 075 person-years Cancer registry Questionnaire Incidence, colorectal cancer, per 100 g/day 1.21 (1.02-1.43) Age, sex, alcohol consumption, body weight, centre location, energy from fat sources, energy from non-fat sources, fibre, height, physical activity, smoking status Continuous results were directly used in dose-response analysis ≥80 vs ≤10 g/day 1.17 (0.92-1.49) 855/ Incidence, colon cancer, per 100 g/day 1.20 (0.96-1.48) ≥80 vs ≤10 g/day 1.20 (0.88-1.61) 474/ Incidence, rectal cancer, per 100 g/day 1.23 (0.94-1.62) ≥80 vs ≤10 g/day 1.13 (0.74-1.71)