Table 3.1: Summary of PFOS immunomodulation animal data (serum concentrations mg/L). et et al. et et al. et et et et et et et et et et 2008 2011 2009 2011 2009 2011 2012a 2012b 2009a 2010a 2010b 2009 al. Qazi Qazi Qazi Guruge Dong Dong Dong Dong Keil Fair Zheng Zheng al. 2011 al. 2008 al. al. al. al. al. al. al. al. al. Lefebvre et 2008 al. Species Mouse Mouse Mouse Rat Mouse B6C3 SD B6C3F1 & ♀ ♂ ♀ Strain B6C3F1 C57BL/6 C57BL/6 ♀ ♂ ♂ ♂ F1♂,♀ Route Gavage Gavage Diet Diet Gavage Days GD 28 28 28 7d 7d 60 60 60 60 10 10 28 28 21d exposed 1-17 a TAD ♂ ♀ mg/kg <LOQ <LOR <LOR 0.048 0.05 ± 0.04 ± 0.04 ± 0.029± 0.04 ± 0.47 ± 0.95 ± 0.002 ± 0 0.005 0.001 ± 0.01 0.01 0.01 0.01 0.01 0.002 0.27 0.51 0.0003 ND 0.05 0.05 0.018 ± 0.004 0.092 1.07 ± 0.58 ± 0.05 ± 0.022 0.11 0.19 0.13 <LOQ 0.189 ± 0.1 ±0.015 0.014 0.67 ± 1.16 ± 0.67 ± 0.67 ± 0.5 0.11 0.09 0.17 0.047 ♀ 2.15 ± 2.36 ± 4.35 ± 4.35 ± ND 1 ND ND 0.55 0.47 0.63 0.63 ~ 1
Table 3.1: Summary of PFOS immunomodulation animal data (serum concentrations mg/L). et al. 2008 Fair et al. 2011 et al. 2011 Keil et al. 2008 Zheng et al. 2009 Zheng et al. 2011 Dong et al. 2009 Dong et al. 2011 Dong et al. 2012a Dong et al. 2012b Qazi et al. 2009a Qazi et al. 2010a Qazi et al. 2010b Lefebvre et al. 2008 Guruge et al. 2009 Species Mouse Mouse Mouse Rat Mouse Strain B6C3 F1♂,♀ B6C3F1 ♀ C57BL/6 ♂ C57BL/6 ♂ ♂ SD ♂ & ♀ B6C3F1 ♀ Route Gavage Gavage Diet Diet Gavage Days exposed 28 28 28 GD 1-17 7d 7d 60 60 60 60 10 10 28 28 21d TAD a mg/kg ♂ ♀ 0 ND <LOR 0.05 <LOR 0.05 0.048 ± 0.01 0.05 ± 0.01 0.04 ± 0.01 0.04 ± 0.01 0.029± 0.01 0.04 ± 0.002 0.47 ± 0.27 0.95 ± 0.51 0.002 ± 0.0003 0.005 0.018 ± 0.004 0.05 0.092 ± 0.022 1.07 ± 0.11 0.58 ± 0.19 0.1 0.13 ±0.015 0.189 ± 0.014 0.5 0.67 ± 0.11 ♀ 1.16 ± 0.09 0.67 ± 0.17 0.67 ± 0.047 1 ND 2.15 ± 0.55 ND ND ~ 1 2.36 ± 0.47 4.35 ± 0.63 4.35 ± 0.63 <LOQ <LOQ 0.001