12 hours PAG6 Synthesis of an Main chemical amino acid and protein – organic solid (paper chemistry, optical isomerism, enzyme The storyline then turns to chromatrography). catalysis and molecular recognition. the chemistry of proteins. Amino acid chemistry, Experiments involving the Accurate use of the following term will be optical isomerism and the hydrolysis of peptides and required: chiral. structure of proteins are carrying out paper The role of chemists in designing drugs is not introduced in relation to the chromatography for – required. structure of insulin. The example and . The role of enzymes in 'green' chemistry is storyline then moves to Test-tube experiments not required. testing for glucose in urine involving acids - for Enzyme kinetics: At low concentrations of as a basis for introducing example . substrate, the with respect to substrate is enzyme catalysis. Various one; at higher concentrations, the order with examples of medicines that respect to substrate is zero. work as enzyme inhibitors are then used to discuss molecular recognition. 3 hours Models of DNA and RNA Main chemical ideas: the structure and (HSW 1) function of DNA and RNA The storyline continues with the development of models Explaining the significance Development of the models of DNA or genetic of the DNA and RNA of hydrogen bonding in the fingerprinting is no longer required. structures and a description pairing of bases in DNA Structure of RNA is new content. Introductory of the Human Genome (HSW 2) notes are available in textbooks and websites project. such as . Discuss how this is taught with your A-level Biology teachers. Monomers of DNA and RNA, and some triplet base codes are given on the .
The storyline then turns to the chemistry of proteins. Amino acid chemistry, optical isomerism and the structure of proteins are introduced in relation to the structure of insulin. The storyline then moves to testing for glucose in urine as a basis for introducing enzyme catalysis. Various examples of medicines that work as enzyme inhibitors are then used to discuss molecular recognition. 12 hours PAG6 – Synthesis of an organic solid (paper chromatrography). Experiments involving the hydrolysis of peptides and carrying out paper chromatography – for example and . Test-tube experiments involving acids - for example . Main chemical amino acid and protein chemistry, optical isomerism, enzyme catalysis and molecular recognition. Accurate use of the following term will be required: chiral. The role of chemists in designing drugs is not required. The role of enzymes in 'green' chemistry is not required. Enzyme kinetics: At low concentrations of substrate, the with respect to substrate is one; at higher concentrations, the order with respect to substrate is zero. The storyline continues with the development of models of the DNA and RNA structures and a description of the Human Genome project. 3 hours Models of DNA and RNA (HSW 1) Explaining the significance of hydrogen bonding in the pairing of bases in DNA (HSW 2) Main chemical ideas: the structure and function of DNA and RNA Development of the models of DNA or genetic fingerprinting is no longer required. Structure of RNA is new content. Introductory notes are available in textbooks and websites such as . Discuss how this is taught with your A-level Biology teachers. Monomers of DNA and RNA, and some triplet base codes are given on the .