(hMSCs) with the enhanced collector Ligaments) mechanobiological properties Human tendon Parallel-aligned Solid nanofiber (430±170nm) Single PLA [] stem/progenitor cells nanofibers needle/rotating (hTSPCs) collector Hydrophilic mitomycin-C Encapsulation of Solid microfibers Single needle; PLA [] (MMC)/hyaluronan (HA) hydrophilic drug; (1.51±0.51~2.24±0.35μm) static collector; hydrosols/NIH/3T3 controlled release micro-sol fibroblasts electrospinning. Basic fibroblast growth Sustained release; Solid nanofiber Single PLGA [] factor (bFGF)/ bone marrow facilitated bone needle/static stem cell (BMSC) marrow stromal collector cells (BMSC) proliferation Patellar tendon cells High cell Solid nanofiber (400-800nm) Single PLGA [] infiltration and needle/static matrix deposition collector Adipose-derived stem cells/ Flexor tendon Solid nanofiber (600-1200nm) Single PLGA [] ECM- like needle/static (GDF-5)/ primary rat structure; collector adipose-derived stem cells (ADSCs) Tendon cells (TCs) Nanoyarn Solid nanofiber (643±97nm) Single PLLACL/collagen [] consisted of needle/rotating twisted nanofibers; collector high porosity; Human ligament fibroblast Parallel-aligned Solid nanofiber (657±183nm) Single PU [] (HLF) nanofibers; needle/rotating biomimetic collector structure; mechanical stimulation pluripotent Well-aligned Solid nanofiber (891±71nm) Single Chitosan/gelatin/PLA/PEO [] stem cells (hiPSCs); ultrafine mat needle/rotating mimicking the collector native tendon's microstructure and mechanical properties
Ligaments) (hMSCs) with the enhanced mechanobiological properties collector Human tendon stem/progenitor cells (hTSPCs) Parallel-aligned nanofibers Solid nanofiber (430±170nm) Single needle/rotating collector PLA [] Hydrophilic mitomycin-C (MMC)/hyaluronan (HA) hydrosols/NIH/3T3 fibroblasts Encapsulation of hydrophilic drug; controlled release Solid microfibers (1.51±0.51~2.24±0.35μm) Single needle; static collector; micro-sol electrospinning. PLA [] Basic fibroblast growth factor (bFGF)/ bone marrow stem cell (BMSC) Sustained release; facilitated bone marrow stromal cells (BMSC) proliferation Solid nanofiber Single needle/static collector PLGA [] Patellar tendon cells High cell infiltration and matrix deposition Solid nanofiber (400-800nm) Single needle/static collector PLGA [] Adipose-derived stem cells/ (GDF-5)/ primary rat adipose-derived stem cells (ADSCs) Flexor tendon ECM- like structure; Solid nanofiber (600-1200nm) Single needle/static collector PLGA [] Tendon cells (TCs) Nanoyarn consisted of twisted nanofibers; high porosity; Solid nanofiber (643±97nm) Single needle/rotating collector PLLACL/collagen [] Human ligament fibroblast (HLF) Parallel-aligned nanofibers; biomimetic structure; mechanical stimulation Solid nanofiber (657±183nm) Single needle/rotating collector PU [] pluripotent stem cells (hiPSCs); Well-aligned ultrafine mat mimicking the native tendon's microstructure and mechanical properties Solid nanofiber (891±71nm) Single needle/rotating collector Chitosan/gelatin/PLA/PEO []