Drug treatment For contraindications or further information please see the current BNF or summary of product characteristics for the individual drug Drug, dose & TLS listing Adverse effects Therapeutic Consultant Clinical relevant drug monitoring interactions GP 1. STIMULANT DRUG TREATMENT 1.1 Methylphenidate [AMBER] Controlled Drug (Schedule 2) Short acting Insomnia 6 monthly height & of hypertensive MAOI’s risk < 6years - unlicensed weight crisis Lost appetite >6 years up to 60mg daily in 6 monthly BP & pulse Moclobemide risk of GI upset – divided doses hypertensive crisis Annually discuss and Headache Long acting consider with the Clonidine, serious adverse Hypertension Concerta XL patient/parent/carer events reported (causality not Reduced weight gain or weight loss < 6years unlicensed interruption of treatment established) Tics >6 years up to 54mg once daily Side effects Rarely blood disorder including Equasym XL Symptom control leucopenia and thrombocytopenia < 6years unlicensed >6 years up to 60mg once daily Medikinet XL < 6years unlicensed >6 years up to 60mg once daily 1.2 Dexamfetamine [AMBER] Controlled Drug (Schedule 2) 4-6yrs - 2.5mg daily (increase by Insomnia 6 monthly height & risk of hypertensive MAOI’s 2.5mg daily at intervals of 1 week) weight crisis Restlessness >6yrs - 5-10mg daily increasing by Moclobemide risk of Anorexia 6 monthly BP & pulse 5mg daily at weekly intervals to a hypertensive crisis GI symptoms Annually discuss and
Drug treatment For contraindications or further information please see the current BNF or summary of product characteristics for the individual drug Drug, dose & TLS listing Adverse effects Therapeutic monitoring Consultant Clinical relevant drug interactions GP 1. STIMULANT DRUG TREATMENT 1.1 Methylphenidate [AMBER] Controlled Drug (Schedule 2) Short acting < 6years - unlicensed >6 years – up to 60mg daily in divided doses Long acting Concerta XL < 6years unlicensed >6 years up to 54mg once daily Equasym XL < 6years unlicensed >6 years up to 60mg once daily Medikinet XL < 6years unlicensed >6 years up to 60mg once daily Insomnia Lost appetite GI upset Headache Hypertension Reduced weight gain or weight loss Tics Rarely blood disorder including leucopenia and thrombocytopenia 6 monthly height & weight 6 monthly BP & pulse Annually discuss and consider with the patient/parent/carer interruption of treatment MAOI’s risk of hypertensive crisis Moclobemide risk of hypertensive crisis Clonidine, serious adverse events reported (causality not established) Side effects Symptom control 1.2 Dexamfetamine [AMBER] Controlled Drug (Schedule 2) 4-6yrs - 2.5mg daily (increase by 2.5mg daily at intervals of 1 week) >6yrs - 5-10mg daily increasing by 5mg daily at weekly intervals to a Insomnia Restlessness Anorexia GI symptoms 6 monthly height & weight 6 monthly BP & pulse Annually discuss and MAOI’s risk of hypertensive crisis Moclobemide risk of hypertensive crisis