COL40662 Prospective 489 611 and national folate intake, person-years by colorectal cancer g/1000kcal/day Ptrend:0.96 USA Cohort, 5 years death Index physical exposure Age: 50-71 activity, red category. Incidence, years, meat intake, intakes in 15 vs 6 1.06 (0.88-1.25) 2 049/ colorectal cancer M/W smoking status, g/1000kcal/day g/1000kcal/day Ptrend:0.55 Men energy converted to intake g/day using Incidence, 15.9 vs 6.6 0.93 (0.72-1.18) Hormone use average energy 1 139/ proximal colon g/1000kcal/day Ptrend:0.68 intake per each cancer quantile Incidence, 17 vs 7 1.10 (0.84-1.43) 925/ colorectal g/1000kcal/day Ptrend:0.45 cancer, women Incidence, distal 15.9 vs 6.6 0.97 (0.73-1.28) 914/ colon cancer g/1000kcal/day Ptrend:0.80 1 138/ 191 011 Incidence, 16.5 vs 6.1 0.62 (0.48-0.79) MEC, 7.3 years colorectal g/kcal/day Ptrend:0.002 Prospective Cancer registry, cancer, men Nomura, 2007 Cohort, death certificate Quantitative 1 023/ COL40655 Age: 45-75 and national FFQ USA years, death Index 18.6 vs 7.5 0.88 (0.67–1.14) 972/ Women M/W g/kcal/day Ptrend:0.245 812/ Incidence, colon 16.5 vs 6.1 0.64 (0.48–0.86)
COL40662 USA Prospective Cohort, Age: 50-71 years, M/W 489 611 5 years and national death Index colorectal cancer g/1000kcal/day Ptrend:0.96 folate intake, physical activity, red meat intake, smoking status, energy intake Hormone use person-years by exposure category. intakes in g/1000kcal/day converted to g/day using average energy intake per each quantile 2 049/ Incidence, colorectal cancer Men 15 vs 6 g/1000kcal/day 1.06 (0.88-1.25) Ptrend:0.55 1 139/ Incidence, proximal colon cancer 15.9 vs 6.6 g/1000kcal/day 0.93 (0.72-1.18) Ptrend:0.68 925/ Incidence, colorectal cancer, women 17 vs 7 g/1000kcal/day 1.10 (0.84-1.43) Ptrend:0.45 914/ Incidence, distal colon cancer 15.9 vs 6.6 g/1000kcal/day 0.97 (0.73-1.28) Ptrend:0.80 Nomura, 2007 COL40655 USA MEC, Prospective Cohort, Age: 45-75 years, M/W 1 138/ 191 011 7.3 years Cancer registry, death certificate and national death Index Quantitative FFQ Incidence, colorectal cancer, men 16.5 vs 6.1 g/kcal/day 0.62 (0.48-0.79) Ptrend:0.002 1 023/ 972/ Women 18.6 vs 7.5 g/kcal/day 0.88 (0.67–1.14) Ptrend:0.245 812/ Incidence, colon 16.5 vs 6.1 0.64 (0.48–0.86)