9. Using Lay Language describe what happens to the animals from the time they are obtained until the time the project is completed. (Background Scientific Data should be included in Q 10). 10. Experimental Plan and Flow Chart (Attach if space is insufficient) If required, attach flow chart at end of document. 11. Administered substances Possible adverse Route Concentration effects of Administered Dose Rate (mg/ml) Frequency administration or substance (mg/kg) & needle total dose (mg) withdrawal of size to be given substance? Anaesthetic Agents Post-Operative Analgesia Tranquillisers Antibiotics Other Substances Research Compounds/Test substances/Devices/ Biologicals Humane Killing Agents 11.1 What experience do you have in using these agents? 11.2 If this project involves the use of an administered substance/ compound for which you do not have full knowledge of its effects, how are you going to manage this? E.g. perform a Pilot Study? 11.3 If novel test compounds are to be used in an experiment or screening assay, what is known about the toxicity of these compounds? Please explain how this information is to be found or the lack of knowledge managed. 12. Animal Number Justification
9. Using Lay Language describe what happens to the animals from the time they are obtained until the time the project is completed. (Background Scientific Data should be included in Q 10). 10. Experimental Plan and Flow Chart (Attach if space is insufficient) If required, attach flow chart at end of document. 11. Administered substances Administered substance Dose Rate (mg/kg) Frequency Route needle size Concentration (mg/ml) & total dose (mg) to be given Possible adverse effects of administration or withdrawal of substance? Anaesthetic Agents Post-Operative Analgesia Tranquillisers Antibiotics Other Substances Research Compounds/Test substances/Devices/ Biologicals Humane Killing Agents 11.1 What experience do you have in using these agents? 11.2 If this project involves the use of an administered substance/ compound for which you do not have full knowledge of its effects, how are you going to manage this? E.g. perform a Pilot Study? 11.3 If novel test compounds are to be used in an experiment or screening assay, what is known about the toxicity of these compounds? Please explain how this information is to be found or the lack of knowledge managed. 12. Animal Number Justification