Supplementary table S3 General characteristics and main findings of the 144 meta-analyses of observational studies Reported N N N Type of Effect model Concordance in Author Year Outcome Population Comparison summary effect Studies Participants Cases metric reported overlapped MA (95% CI) Cardiovascular outcomes Tamariz ADDIN EN.CITE Atrial fibrillation Highest vs lowest SUA 2014 General 3 138,306 3,466 RR Random 1.67 (1.23, 2.27) incidence category YES ADDIN EN.CITE Atrial fibrillation Xu12 2015 General Hyper vs normal 7 85,530 NA RR Random 1.80 (1.37, 2.38) incidence Atrial fibrillation Xu12 2015 General Hyper vs normal 5 84,837 NA RR Random 1.66 (1.22, 2.26) new-onset Atrial fibrillation Zhang13 2016 General Hyper vs normal 6 426,159 7,595 RR Random 1.49 (1.24, 1.79) incidence Tamariz ADDIN Atrial fibrillation vs 2014 Atrial fibrillation SUA level (mg/dl) 6 7,930 1,603 SMD Random 0.42 (0.27, 0.58) EN.CITE controls
Supplementary table S3 General characteristics and main findings of the 144 meta-analyses of observational studies Author Year Outcome Population Comparison N Studies N Participants N Cases Type of metric Effect model reported Reported summary effect (95% CI) Concordance in overlapped MA Cardiovascular outcomes Tamariz ADDIN EN.CITE 2014 Atrial fibrillation incidence General Highest vs lowest SUA category 3 138,306 3,466 RR Random 1.67 (1.23, 2.27) YES ADDIN EN.CITE Xu12 2015 Atrial fibrillation incidence General Hyper vs normal 7 85,530 NA RR Random 1.80 (1.37, 2.38) Xu12 2015 Atrial fibrillation new-onset General Hyper vs normal 5 84,837 NA RR Random 1.66 (1.22, 2.26) Zhang13 2016 Atrial fibrillation incidence General Hyper vs normal 6 426,159 7,595 RR Random 1.49 (1.24, 1.79) Tamariz ADDIN EN.CITE 2014 Atrial fibrillation Atrial fibrillation vs controls SUA level (mg/dl) 6 7,930 1,603 SMD Random 0.42 (0.27, 0.58)