Hematemesis; melena; hemoglobin 6.9; large duodenal ulcer in bulb; nodular 17 y M gastropathy 3 3 H. pylori 3 TABLE 1 LEGEND Demographic, clinical, pathological and immunostain data from 42 pediatric α-synuclein endoscopic biopsies. Pediatric cases were selected with pathological and/or clinical diagnoses of gastritis, duodenitis, and gastropathy. Slides were stained with and scored H. pylori, α-synuclein for by two pathologists for neurite presence and intensity, as well as inflammation α-synuclein as follows: 1, slight; 2, moderate; 3, high. Acute and chronic inflammation was scored as 1, slight; 2, moderate; 3, intense, based on the degree of infiltration of neutrophils or mononuclear cells, respectively. and inflammation scores are the average of the two readings. α-synuclein TABLE 2A Age at Sex of Underlying Donor Organs Patient Viral infection timeline Comment transplant recipient condition age transplanted 0 months: Norovirus [RNA PCR] 1 2 y M Volvulus 0.4 y Li/SB/Pa - 8 years: Rotavirus (x4) [Rota antigen, stool] + 2 months: Norovirus [RNA PCR] Persistent norovirus 0 months: Norovirus [RNA PCR] infection at 2 1.5 y F NEC 1 y SB - 2 months: [C. diff toxin biopsy C. difficile gene PCR, stool] - 2 years: CMV [CMV IgG, blood]
17 y M Hematemesis; melena; hemoglobin 6.9; large duodenal ulcer in bulb; nodular gastropathy 3 3 H. pylori 3 TABLE 1 LEGEND Demographic, clinical, pathological and α-synuclein immunostain data from 42 pediatric endoscopic biopsies. Pediatric cases were selected with pathological and/or clinical diagnoses of gastritis, duodenitis, H. pylori, and gastropathy. Slides were stained with α-synuclein and scored for by two pathologists for neurite α-synuclein presence and intensity, as well as inflammation as follows: 1, slight; 2, moderate; 3, high. Acute and chronic inflammation was scored as 1, slight; 2, moderate; 3, intense, based on the degree of infiltration of neutrophils or mononuclear cells, respectively. α-synuclein and inflammation scores are the average of the two readings. TABLE 2A Patient Age at transplant Sex of recipient Underlying condition Donor age Organs transplanted Viral infection timeline Comment 1 2 y M Volvulus 0.4 y Li/SB/Pa 0 months: Norovirus [RNA PCR] - 8 years: Rotavirus (x4) [Rota antigen, stool] 2 1.5 y F NEC 1 y SB + 2 months: Norovirus [RNA PCR] 0 months: Norovirus [RNA PCR] - 2 months: C. difficile [C. diff toxin gene PCR, stool] - 2 years: CMV [CMV IgG, blood] Persistent norovirus infection at biopsy