Human Genetic Disorders Recognize that DNA contains hereditary information and the importance & Molecule to Phenotype application of the Human Genome Project. Chromosomal Disorders Describe how chromosomes can be damaged. Identify the gene or chromosomal mutation involved in human disorders such Human Genome as syndrome, disease, Hemophilia and Tay-Sachs Down’s Huntington’s Manipulating DNA disease. The Human Genome Project Recognize disorders caused by sex-linked genes and predict outcomes using Punnett squares. Causes of Genetic diseases Identify chromosomal disorders by looking at a karyotype. Non-disjunction during meiosis Identify types of diseases and/or disorders and list their effects upon the Damaged Chromosomes (duplication, deletion, inversion, and translocation) human body (degenerative, deficiency, hereditary, and contagious). Gene mutation (e.g. Tay-Sachs disease) Identify conditions or disorders presented in a pedigree. Summarize the methods of DNA analysis. Chromosomal Disorders State the goals of the Human Genome Project and explain what we have Autosomal Chromosomes (Down Syndrome or Trisomy 21) learned so far. Sex Chromosomes Syndrome & other Trisomy (Turner’s Syndrome, Klinefelter’s Describe the inheritance of a sex-linked gene such as color-blindness. conditions) Sex-Linked Genes Definition Disorders (Colorblindness and Hemophilia) Morgan and Fruit fly eye color Punnett square problems Examining Human Chromosomes & Traits Karyotype Pedigree (automosal or sex-linked, dominant or recessive; e.g. Huntington’s disease)
Human Genetic Disorders Molecule to Phenotype Chromosomal Disorders Human Genome Manipulating DNA The Human Genome Project Causes of Genetic diseases Non-disjunction during meiosis Damaged Chromosomes (duplication, deletion, inversion, and translocation) Gene mutation (e.g. Tay-Sachs disease) Chromosomal Disorders Autosomal Chromosomes (Down Syndrome or Trisomy 21) Sex Chromosomes (Turner’s Syndrome, Klinefelter’s Syndrome & other Trisomy conditions) Sex-Linked Genes Definition Disorders (Colorblindness and Hemophilia) Morgan and Fruit fly eye color Punnett square problems Examining Human Chromosomes & Traits Karyotype Pedigree (automosal or sex-linked, dominant or recessive; e.g. Huntington’s disease) Recognize that DNA contains hereditary information and the importance & application of the Human Genome Project. Describe how chromosomes can be damaged. Identify the gene or chromosomal mutation involved in human disorders such as Down’s syndrome, Huntington’s disease, Hemophilia and Tay-Sachs disease. Recognize disorders caused by sex-linked genes and predict outcomes using Punnett squares. Identify chromosomal disorders by looking at a karyotype. Identify types of diseases and/or disorders and list their effects upon the human body (degenerative, deficiency, hereditary, and contagious). Identify conditions or disorders presented in a pedigree. Summarize the methods of DNA analysis. State the goals of the Human Genome Project and explain what we have learned so far. Describe the inheritance of a sex-linked gene such as color-blindness.