Comparative study Rosario et al. (2012) No III-2 UK n: 1,147 TRUSGB Haematuria with concurrent Multiple Age: 62.1 (5.1) Cores: NR Rectal bleeding controls hospitals Haematospermia PSA: 4.2 (3.5-5.8) Enema: NR Non-consecutive Pain Prior biopsy: 0 Needle: NR Fever Prospective Simsir et al. (2010) No Case series IV Turkey n: 2,023 TRUSGB Major infection Consecutive Tertiary Age: 64.3 (10.1) Cores: 12 [10-20] Death hospital Retrospective PSA: 26.7 Enema: 100 Prior biopsy: mix Needle: NR Zaytoun et al. (2011) No Case series IV USA n: 1,348 TRUSGB Minor infection Non-consecutive Tertiary Age: 64.4 (8.7) Cores: 12 [10-20] Major infection hospital Retrospective PSA: 8.0 (4.0-8.1) Enema: 35 Urinary obstruction Prior biopsy: NR Needle: NR Haematuria Rectal bleeding Haematospermia Helfand et al. (2012) No Case series IV USA n: 85 TRUSGB Erectile dysfunction Non-consecutive Tertiary Age:61.0 (8.3) Cores: 12 hospital Prospective PSA: 52 (3.4) Enema: NR Prior biopsy: 0 Needle: NR Kariotis et al. (2010) No Comparative study III-2 Greece n: 434 TRUSGB Haematuria with concurrent Tertiary Age: 65.4 Cores: 12 + targeted Rectal bleeding controls hospital Haematospermia PSA: 7.4 Enema: NR Non-consecutive Prior biopsy: 0 Needle: 18G Prospective
Rosario et al. (2012) No Comparative study with concurrent controls Non-consecutive Prospective III-2 UK Multiple hospitals n: 1,147 Age: 62.1 (5.1) PSA: 4.2 (3.5-5.8) Prior biopsy: 0 TRUSGB Cores: NR Enema: NR Needle: NR Haematuria Rectal bleeding Haematospermia Pain Fever Simsir et al. (2010) No Case series Consecutive Retrospective IV Turkey Tertiary hospital n: 2,023 Age: 64.3 (10.1) PSA: 26.7 Prior biopsy: mix TRUSGB Cores: 12 [10-20] Enema: 100 Needle: NR Major infection Death Zaytoun et al. (2011) No Case series Non-consecutive Retrospective IV USA Tertiary hospital n: 1,348 Age: 64.4 (8.7) PSA: 8.0 (4.0-8.1) Prior biopsy: NR TRUSGB Cores: 12 [10-20] Enema: 35 Needle: NR Minor infection Major infection Urinary obstruction Haematuria Rectal bleeding Haematospermia Helfand et al. (2012) No Case series Non-consecutive Prospective IV USA Tertiary hospital n: 85 Age:61.0 (8.3) PSA: 52 (3.4) Prior biopsy: 0 TRUSGB Cores: 12 Enema: NR Needle: NR Erectile dysfunction Kariotis et al. (2010) No Comparative study with concurrent controls Non-consecutive Prospective III-2 Greece Tertiary hospital n: 434 Age: 65.4 PSA: 7.4 Prior biopsy: 0 TRUSGB Cores: 12 + targeted Enema: NR Needle: 18G Haematuria Rectal bleeding Haematospermia