frequent mobilisation protocol N= 8,590 sore of 0-2. pneumonia) or neurological (stroke also change as they are within 24 h of stroke onset is not progression, recurrent strokes). updated. better than usual care. Outcome Difference in risk N if implemented Health Economic Impact QALY Economic Total Economic Impact between control at 65% service on health service impact per impact on and treatment cost per costs if person QALYS if person or implemented implemented day Primary Based on $ difference for Functional outcomes treatment and at 3 months (Rankin -5,584 -$65 -$0.4m -$9,953 -$56m -$56m QALY between scale score). treatment and control groups. Secondary None statistically - - - - - - - significant. Change in -$2m intervention costs Totals -$0.4m -$56m -$58m Columns may not sum due to rounding. Negative values are savings in the calculations. PE = pulmonary embolism. DVT = deep vein thrombosis. UTI = urinary tract infection. Health Health Service service/outcome Explanation and costing assumptions Reference or Outcome cost per person or day Tan Tanny et al. (2013). Cost-Effectiveness of Thrombolysis Within 4.5 Incremental difference between functional outcomes at 3 months are translated Hours of Acute Ischemic Stroke. Stroke. 44:2269-2274. into treatment costs and QALYs preserved. Functional Service cost: Harald Hannerz et al. (2001). Life Expectancies Among Survivors of Treatment costs for stroke are based on cost breakdown by functional outcome outcomes at 3 -$65 Acute Cerebrovascular Disease. in Tan Tanny (2013). months (Rankin scale score) Slot et al. (2008). Impact of functional status at six months on long term QALY: -$9,953 Life expectancies for these patients range from an additional 0 to 6.4 years, survival in patients with ischaemic stroke: prospective cohort studies. based on average age of patients in the study. Additional reference is taken from Harald Hannerz et al. (2001). Cross-checked with Slot et al. (2008) and Hong et al. (2010). Years of Optimum Health Lost Due to Complications
frequent mobilisation protocol within 24 h of stroke onset is not better than usual care. sore of 0-2. pneumonia) or neurological (stroke progression, recurrent strokes). also change as they are updated. N= 8,590 Outcome Difference in risk between control and treatment N if implemented at 65% Health service cost per person or day Economic Impact on health service costs if implemented QALY impact per person Economic impact on QALYS if implemented Total Economic Impact Primary Functional outcomes at 3 months (Rankin scale score). Based on $ difference for treatment and QALY between treatment and control groups. -5,584 -$65 -$0.4m -$9,953 -$56m -$56m Secondary None statistically significant. - - - - - - - Change in intervention costs Totals -$2m -$0.4m -$56m -$58m Columns may not sum due to rounding. Negative values are savings in the calculations. PE = pulmonary embolism. DVT = deep vein thrombosis. UTI = urinary tract infection. Health Service or Outcome Health service/outcome cost per person or day Explanation and costing assumptions Reference Functional outcomes at 3 months (Rankin scale score) Service cost: -$65 QALY: -$9,953 Incremental difference between functional outcomes at 3 months are translated into treatment costs and QALYs preserved. Treatment costs for stroke are based on cost breakdown by functional outcome in Tan Tanny (2013). Life expectancies for these patients range from an additional 0 to 6.4 years, based on average age of patients in the study. Additional reference is taken from Harald Hannerz et al. (2001). Cross-checked with Slot et al. (2008) and Tan Tanny et al. (2013). Cost-Effectiveness of Thrombolysis Within 4.5 Hours of Acute Ischemic Stroke. Stroke. 44:2269-2274. Harald Hannerz et al. (2001). Life Expectancies Among Survivors of Acute Cerebrovascular Disease. Slot et al. (2008). Impact of functional status at six months on long term survival in patients with ischaemic stroke: prospective cohort studies. Hong et al. (2010). Years of Optimum Health Lost Due to Complications