perspective on diagnosis, clinical features and management. Diagnosis is Refractory acute ITP on the recommendation of a Yes Which Haematologist Specialties of treating specialists are required to required clinical haematologist Speciality or General be identified within the Ig system. (A) Physician Diagnosis must No Which be verified Specialty Exclusion Criteria Indication for Refractory acute ITP — initial therapy. Refractory ITP and pregnancy have each been 1. Refractory acute ITP on the recommendation use split into 2 indications to support initial of a clinical haematologist treatment and then ongoing therapy in those Refractory acute ITP — splenectomy failed or patients requiring monthly Ig treatment. Eg Patients with severe thrombocytopenia (platelets contraindicated and second-line agent refractory ITP when splenectomy has failed and unsuccessful. ongoing treatment for ITP responders during <30x109/L) who have not responded to pregnancy. corticosteroid therapy. ITP with life-threatening haemorrhage or the 2. ITP with life-threatening haemorrhage or the potential for life-threatening haemorrhage. potential for life-threatening haemorrhage Initial therapy for ITP in pregnancy. Patients with severe thrombocytopenia (<30x109/L) with clinical evidence of a haemostatic defect (e.g. mucous membrane Ongoing treatment for ITP responders during haemorrhage) or active bleeding. pregnancy and the postpartum period.
perspective on diagnosis, clinical features and management. Diagnosis is required Refractory acute ITP on the recommendation of a clinical haematologist Yes Which Speciality Haematologist or General Physician Specialties of treating specialists are required to be identified within the Ig system. (A) Diagnosis must be verified No Which Specialty Exclusion Criteria Indication for use 1. Refractory acute ITP on the recommendation of a clinical haematologist Patients with severe thrombocytopenia (platelets <30x109/L) who have not responded to corticosteroid therapy. 2. ITP with life-threatening haemorrhage or the potential for life-threatening haemorrhage Patients with severe thrombocytopenia (<30x109/L) with clinical evidence of a haemostatic defect (e.g. mucous membrane haemorrhage) or active bleeding. Refractory acute ITP — initial therapy. Refractory acute ITP — splenectomy failed or contraindicated and second-line agent unsuccessful. ITP with life-threatening haemorrhage or the potential for life-threatening haemorrhage. Initial therapy for ITP in pregnancy. Ongoing treatment for ITP responders during pregnancy and the postpartum period. Refractory ITP and pregnancy have each been split into 2 indications to support initial treatment and then ongoing therapy in those patients requiring monthly Ig treatment. Eg refractory ITP when splenectomy has failed and ongoing treatment for ITP responders during pregnancy.