P2 Heartburn (n=7), regurgitation (n=6) severe oesophagitis (Los Angeles grade or both symptoms (n=26) C or above), pregnancy, women who were not using reliable contraception Foreign-body Domingues, Retrospective 100 patients Inclusion: Index test: sensation Moraes-Filho & case series (probe successfully attached in 95 Patients referred to a GI motility System: Bravo™ wireless capsule system Chest pain Domingues () patients) laboratory to investigate GORD with Insertion: 5 cm above the upper border of Motility laboratory typical or atypical symptoms, persistent Level: IV 39 female, 61 male the LOS (manometry) or 6 cm above the (Gastro GORD symptoms on medical therapy or LOS (endoscopy) Quality: Q2 Mean age: 53 years (range 18– 81) Resolucao recurrent GORD symptoms after surgical Placement: transorally Diagnostico, fundoplication, between 2004 and 2009 CX (no Indications: Laboratorio de comparator) Duration: 48 hours Exclusion: 82% were referred to diagnose Motilidade P2 GORD, 18% were referred due to Comparator: NA <18 years of age, history of bleeding Digestive), Rio de persistent symptoms despite PPI use tendency or coagulopathy, significant Janeiro, Brazil concomitant medical co-morbidities, severe GI bleeding in the past 6 months, a history of upper GI surgery, medication with PPIs, presence of oesophageal varices, Barrett’s oesophagus, oesophageal stenosis, erosive oesophagitis, pacemaker or implantable cardiac defibrillator in situ Mucosal tear with Fajardo et al. () Case report 1 patient Inclusion: Index test: oesophageal Division of 76 year old woman NA System: Bravo™ wireless capsule system perforation Gastroenterology Level: NA Indication: Exclusion: Insertion: not stated and Hepatology, Recurrent GORD, failing to respond NA Placement: not stated Mayo Clinic to medical therapy College of Duration: NA Medicine, Comparator: NA Rochester, Minnesota, USA Severe chest pain Francis, DL () Retrospective 76 patients Inclusion: Index test: Capsule case series Miles and Shirley Not stated System: Bravo™ wireless capsule system
P2 Heartburn (n=7), regurgitation (n=6) or both symptoms (n=26) severe oesophagitis (Los Angeles grade C or above), pregnancy, women who were not using reliable contraception Domingues, Moraes-Filho & Domingues () Motility laboratory (Gastro Resolucao Diagnostico, Laboratorio de Motilidade Digestive), Rio de Janeiro, Brazil Retrospective case series Level: IV Quality: Q2 CX (no comparator) P2 100 patients (probe successfully attached in 95 patients) 39 female, 61 male Mean age: 53 years (range 18– 81) Indications: 82% were referred to diagnose GORD, 18% were referred due to persistent symptoms despite PPI use Inclusion: Patients referred to a GI motility laboratory to investigate GORD with typical or atypical symptoms, persistent GORD symptoms on medical therapy or recurrent GORD symptoms after surgical fundoplication, between 2004 and 2009 Exclusion: <18 years of age, history of bleeding tendency or coagulopathy, significant concomitant medical co-morbidities, severe GI bleeding in the past 6 months, a history of upper GI surgery, medication with PPIs, presence of oesophageal varices, Barrett’s oesophagus, oesophageal stenosis, erosive oesophagitis, pacemaker or implantable cardiac defibrillator in situ Index test: System: Bravo™ wireless capsule system Insertion: 5 cm above the upper border of the LOS (manometry) or 6 cm above the LOS (endoscopy) Placement: transorally Duration: 48 hours Comparator: NA Foreign-body sensation Chest pain Fajardo et al. () Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA Case report Level: NA 1 patient 76 year old woman Indication: Recurrent GORD, failing to respond to medical therapy Inclusion: NA Exclusion: NA Index test: System: Bravo™ wireless capsule system Insertion: not stated Placement: not stated Duration: NA Comparator: NA Mucosal tear with oesophageal perforation Francis, DL () Miles and Shirley Retrospective case series 76 patients Inclusion: Not stated Index test: System: Bravo™ wireless capsule system Severe chest pain Capsule