EVALUATION OF TOXICOLOGICAL DATA The notified chemical decomposes in the presence of water to antimony trioxide and acetic acid. Therefore, studies conducted with antimony trioxide are included in this section. Acute Toxicity Summary of the toxicity of antimony triacetate Test Species Outcome Reference acute oral toxicity severe irritant No. 1 LD50 > 2.5 rat severe irritant study No. 2 g/kg LD50 = 7 rat study No. 3 g/kg rat acute dermal (Heenehan et al., LD50 >50 - < 5000 toxicity 1977b) (Fegley, mg/kg rabbit 1967b) (Budd, No. 1 rabbit study No. 2 1967) LD50 > 2 g/kg rabbit study No. 3 LD50 > 2 g/kg rabbit LD50 > 12.8 study No. 4 (Budd, 1967) g/kg LD50 > 8 skin irritation (Heenehan et al., g/kg rabbit 1977a) (Fegley, 1967a) study No. 1 rabbit study No. 2 (Gabriel, undated) Corrosive rabbit study No. 3 slight irritant (Stachowiak & Baker, moderate to severe rabbit study No. 4 1975) (Edmonds, 1967b) irritant rabbit study No. 5 (Budd, 1967) severe irritant rabbit No. 6 severe irritant (Heenehan et al., corrosive under eye irritation 1977c) (Gabriel, humid conditions rabbit No. 1 undated) (Chang, 1981) rabbit No. 2 severe irritant rabbit No. 3
EVALUATION OF TOXICOLOGICAL DATA The notified chemical decomposes in the presence of water to antimony trioxide and acetic acid. Therefore, studies conducted with antimony trioxide are included in this section. Acute Toxicity Summary of the toxicity of antimony triacetate Test Species Outcome Reference acute oral toxicity No. 1 study No. 2 study No. 3 acute dermal toxicity No. 1 study No. 2 study No. 3 study No. 4 skin irritation study No. 1 study No. 2 study No. 3 study No. 4 study No. 5 No. 6 eye irritation No. 1 No. 2 No. 3 rat rat rat rabbit rabbit rabbit rabbit rabbit rabbit rabbit rabbit rabbit rabbit rabbit rabbit rabbit LD50 > 2.5 g/kg LD50 = 7 g/kg LD50 >50 - < 5000 mg/kg LD50 > 2 g/kg LD50 > 2 g/kg LD50 > 12.8 g/kg LD50 > 8 g/kg Corrosive slight irritant moderate to severe irritant severe irritant severe irritant corrosive under humid conditions severe irritant severe irritant severe irritant (Heenehan et al., 1977b) (Fegley, 1967b) (Budd, 1967) (Budd, 1967) (Heenehan et al., 1977a) (Fegley, 1967a) (Gabriel, undated) (Stachowiak & Baker, 1975) (Edmonds, 1967b) (Budd, 1967) (Heenehan et al., 1977c) (Gabriel, undated) (Chang, 1981)