In addition, for treatment of ankylosing spondylitis: Requires a response to 18 years of age or older treatment Trial and failure of all of the following: 2 formulary NSAIDs within the last 60 days (or documented contraindication or intolerance to NSAIDs) Enbrel or Humira for 3 consecutive months (or documented contraindication or intolerance to Enbrel and Humira) In addition, for treatment of moderate to severe active Crohn’s Disease: 6 years of age or older Trial and failure of all of the following: Oral corticosteroids (for moderate to severe CD) or intravenous corticosteroids (for severe and fulminant CD) for one (or documented contraindication or intolerance to PO or IV corticosteroids) Azathioprine or mercaptopurine for 3 consecutive months (or documented contraindication or intolerance to azathioprine or mercaptopurine) Trial and failure of parenteral methotrexate (Adults) Humira for 3 consecutive months (or documented contraindication or intolerance to Humira) In addition, for treatment of fistulizing Crohn’s Disease: 18 of age or older Diagnosis of fistulizing Crohn’s Disease In addition, for treatment of chronic severe plaque psoriasis: 18 years of age or older Trial and failure of all of the following: UVB or PUVA therapy or contraindication to therapy Methotrexate for 3 consecutive months (or contraindication/intolerance to methotrexate) Enbrel or Humira for 3 consecutive months (or contraindication/ intolerance to Enbrel and Humira)
In addition, for treatment of ankylosing spondylitis: 18 years of age or older Trial and failure of all of the following: 2 formulary NSAIDs within the last 60 days (or documented contraindication or intolerance to NSAIDs) Enbrel or Humira for 3 consecutive months (or documented contraindication or intolerance to Enbrel and Humira) In addition, for treatment of moderate to severe active Crohn’s Disease: 6 years of age or older Trial and failure of all of the following: Oral corticosteroids (for moderate to severe CD) or intravenous corticosteroids (for severe and fulminant CD) for one (or documented contraindication or intolerance to PO or IV corticosteroids) Azathioprine or mercaptopurine for 3 consecutive months (or documented contraindication or intolerance to azathioprine or mercaptopurine) Trial and failure of parenteral methotrexate (Adults) Humira for 3 consecutive months (or documented contraindication or intolerance to Humira) In addition, for treatment of fistulizing Crohn’s Disease: 18 of age or older Diagnosis of fistulizing Crohn’s Disease In addition, for treatment of chronic severe plaque psoriasis: 18 years of age or older Trial and failure of all of the following: UVB or PUVA therapy or contraindication to therapy Methotrexate for 3 consecutive months (or contraindication/intolerance to methotrexate) Enbrel or Humira for 3 consecutive months (or contraindication/ intolerance to Enbrel and Humira) Requires a response to treatment