Section 12. Ecological information Toxicity for Daphnia Static EU EC C.1 Acute Chronic LCO 96 hours Fish >0.57 mg/I Toxicity for Fish Semi-static EU EC C.3 Algal Chronic NOEC 72 >0.42 mg/I Inhibition Test Static OECD OECD 202: Chronic NOEC 21 days Daphnia 0.316 mg/I Part II (Daphnia sp., Semi-static Reproduction Test 4,4'-Methylenediphenyl OECD 201 Alga, Acute EC50 72 hours Algae >1640 mg/I diisocyanate, oligomeric Growth Inhibition Static reaction products with butane- Test 1,3-diol, 2,4'- diisocyanatodiphenylmethane, 1,1'-methylenebis (4-isocyanatobenzene) homopolymer, [ (methylethylene)bis(oxy)] dipropanol and propane-1, 2-diol OECD 209 Acute EC50 3 hours Bacteria >100 mg/I Activated Sludge, Static Respiration Inhibition Test OECD 202 24 hours Acute EC50 Daphnia >1000 Daphnia sp. Acute Static Immobilization Test OECD 203 Fish, 96 hours Acute LC50 Fish >1000 Toxicity Test Static OECD 211 Daphnia Chronic NOEC 21 days Daphnia >10 Magna Semi-static Reproduction Test Persistence and degradability Result Product/ingredient name Test Period Diphenylmethane 4,4'- OECD 302C Inherent 28 days 0 % diisocyanate Biodegradability: Modified MITI Test Homopolymer of OECD (II) 302C Inherent 28 days 0 % methylenediphenyl Biodegradability: Modified MITI Test diisocyanate (II) 4,4'-Methylenediphenyl OECD 302C Inherent 28 days 0 % diisocyanate, oligomeric Biodegradability: Modified MITI Test reaction products with (II) 1,1'-methylenebis homopolymer, [ (methylethylene)bis(oxy)] dipropanol and propane-1, Conclusion/Summary : 4,4'-Methylenediphenyl Not biodegradable diisocyanate 8/5/2014. Not available. 15/20
Section 12. Ecological information Toxicity for Daphnia Static EU EC C.1 Acute Chronic LCO 96 hours Fish >0.57 mg/I Toxicity for Fish Semi-static EU EC C.3 Algal Chronic NOEC 72 >0.42 mg/I Inhibition Test Static OECD OECD 202: Chronic NOEC 21 days Daphnia 0.316 mg/I Part II (Daphnia sp., Reproduction Test Semi-static 4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with butane- OECD 201 Alga, Growth Inhibition Test Acute EC50 72 hours Static Algae >1640 mg/I 1,3-diol, 2,4'- diisocyanatodiphenylmethane, 1,1'-methylenebis (4-isocyanatobenzene) homopolymer, [ (methylethylene)bis(oxy)] dipropanol and propane-1, 2-diol OECD 209 Acute EC50 3 hours Bacteria >100 mg/I Activated Sludge, Respiration Static Inhibition Test OECD 202 Daphnia sp. Acute Acute EC50 24 hours Static Daphnia >1000 Immobilization Test OECD 203 Fish, Toxicity Test Acute LC50 96 hours Static Fish >1000 OECD 211 Daphnia Chronic NOEC 21 days Daphnia >10 Magna Semi-static Reproduction Test Persistence and degradability Product/ingredient name Test Period Result Diphenylmethane 4,4'- diisocyanate OECD 302C Inherent Biodegradability: Modified MITI Test (II) 28 days 0 % Homopolymer of methylenediphenyl diisocyanate OECD 302C Inherent Biodegradability: Modified MITI Test (II) 28 days 0 % 4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with 1,1'-methylenebis homopolymer, [ (methylethylene)bis(oxy)] dipropanol and propane-1, OECD 302C Inherent Biodegradability: Modified MITI Test (II) 28 days 0 % Conclusion/Summary : 4,4'-Methylenediphenyl Not biodegradable diisocyanate 8/5/2014. Not available. 15/20