Table : Summary of diagnostic accuracy for HbA1c testing vs WHO criteria (2006) for diagnosing diabetes and pre-diabetes in people with and without anaemia Patients Reference HbA1c Sensitivity Specificity PPV NPV Concordance standard cut-off [95%CI] 95%CI] [95%CI] [95%CI] (mmol/L) point N = 77 FPG ≥6.1 5.7% 37.5% [13.7, 84.1% [73.7, 21.4% [7.6, 92.1% [82.7, 0.162 [0.000, 69.4] 90.9] 47.6] 96.6] 0.527] 2hPG ≥7.8 anaemic patients N = 39 75.0% [30.0, 62.9% [46.3, 18.8% [6.6, 95.7% [79.0, 0.163 [0.000, FPG ≥6.1 5.7% 95.4] 76.8] 43.0] 99.2] 0.514] 2hPG ≥7.8 patients Source: Hardikar ()
Table : Summary of diagnostic accuracy for HbA1c testing vs WHO criteria (2006) for diagnosing diabetes and pre-diabetes in people with and without anaemia Patients Reference standard (mmol/L) HbA1c cut-off point Sensitivity [95%CI] Specificity 95%CI] PPV [95%CI] NPV [95%CI] Concordance N = 77 patients FPG ≥6.1 2hPG ≥7.8 5.7% 37.5% [13.7, 69.4] 84.1% [73.7, 90.9] 21.4% [7.6, 47.6] 92.1% [82.7, 96.6] 0.162 [0.000, 0.527] N = 39 anaemic patients FPG ≥6.1 2hPG ≥7.8 5.7% 75.0% [30.0, 95.4] 62.9% [46.3, 76.8] 18.8% [6.6, 43.0] 95.7% [79.0, 99.2] 0.163 [0.000, 0.514] Source: Hardikar ()