Citation Method of Allocation Blinding Loss to Use of Ceasing Reporting Funding source randomisation concealment early for benefit all where outcome required results Melander Unclear risk Unclear risk Participants: 15% loss to No (high risk) No (low risk) Yes (low Swedish et al. (method of (method of low risk follow-up (and risk) Medical (2007) randomisation not allocation unclear from Research Providers: low stated) concealment not study Council and risk stated) period) other research – unclear risk bodies (low risk) Outcome assessors: unclear Summary table Citation Study Population Intervention Outcomes Sample Intervention Compliance to Results & design level measured size duration sodium target location of relevant to (urinary data) research question Morgan II Adult males Participants Blood pressure 62 2 Restricted sodium Mean difference (supine), et al. (more than 50 randomly divided group: 157 (SEM: 7) between restricted mortality (1978), parallel years), with into four groups: mmol/24hr and control sodium Australia design borderline diet: BP also 1. Control group hypertension measured [] (no treatment) Supine: standing,
Citation Method of randomisation Allocation concealment Blinding Loss to Use of where required Ceasing early for benefit Reporting all outcome results Funding source Melander et al. (2007) Unclear risk (method of randomisation not stated) Unclear risk (method of allocation concealment not stated) Participants: low risk Providers: low risk Outcome assessors: unclear 15% loss to follow-up (and unclear from study period) – unclear risk No (high risk) No (low risk) Yes (low risk) Swedish Medical Research Council and other research bodies (low risk) Summary table Citation & location Study design level of Population Intervention Outcomes measured relevant to research question Sample size Intervention duration Compliance to sodium target (urinary data) Results Morgan et al. (1978), Australia [] parallel design II Adult males (more than 50 years), with borderline hypertension Participants randomly divided into four groups: 1. Control group (no treatment) Blood pressure (supine), mortality BP also measured standing, 62 2 Restricted sodium group: 157 (SEM: 7) mmol/24hr Mean difference between restricted and control sodium diet: Supine: