28 days Sex not Veterans Grundy, 1986 Randomized 1. 3.8 26.9 7.7 Initial: 7, final: 7 reported Administration No dropouts crossover design Mean age: 58 National Institutes USA 2. 6.4 6.4 6.4 reported years of Health with two Southwestern interventions Medical Foundation Mead Johnson and Company Experimental Moss Heart period: Foundation 28 days 37 men and 23 The Netherlands Brussaard et al., Randomized 1. 8.0 10.0 3.0 Initial: 60, final: 60 women Heart Foundation No dropouts 1980 parallel design Diet 1: 16 2. 10.0 8.0 11.0 reported subjects with four The Netherlands Diet 2: 15 interventions 3. 11.0 8.0 19.0 subjects Diet 3: 15 Experimental 4. 18.0 16.0 3.0 subjects period: Diet 4: 14 subjects 35 days
28 days Grundy, 1986 USA Randomized crossover design with two interventions Experimental period: 28 days 1. 2. 3.8 6.4 26.9 6.4 7.7 6.4 Initial: 7, final: 7 No dropouts reported Sex not reported Mean age: 58 years Veterans Administration National Institutes of Health Southwestern Medical Foundation Mead Johnson and Company Moss Heart Foundation Brussaard et al., 1980 The Netherlands Randomized parallel design with four interventions Experimental period: 35 days 1. 2. 3. 4. 8.0 10.0 11.0 18.0 10.0 8.0 8.0 16.0 3.0 11.0 19.0 3.0 Initial: 60, final: 60 No dropouts reported 37 men and 23 women Diet 1: 16 subjects Diet 2: 15 subjects Diet 3: 15 subjects Diet 4: 14 subjects The Netherlands Heart Foundation