similar to OECD TG 401 (Organisation for Test method: Economic Co-operation and Development, > 2 000 mg.kg-1 LD50: the notified chemical is of low acute oral toxicity in Result: rats 9.1.2 Dermal Toxicity (Tuffnell, 1992b) rat/Sprague-Dawley Species/strain: 5/sex Number/sex of animals: 14 days Observation period: dose of 2 000 mg.kg-1 of the notified chemical was Method of administration: applied to an area of shaved skin for 24 hours under an occlusive dressing no signs of systemic toxicity were observed; Clinical observations: desquamation was noted at the treatment sites of four females three to six days after dosing and persisted in two females seven days after dosing nil Mortality: nil Morphological findings: similar to OECD TG 402 (Organisation for Test method: Economic Co-operation and Development, > 2 000 mg.kg-1 LD50: the notified chemical is of low acute toxicity when Result: applied dermally to rats 9.1.3 Inhalation Toxicity No study was provided by the notifier. 9.1.4 Skin Irritation (Tuffnell, 1992c) rabbit/New Zealand White Species/strain:
Test method: similar to OECD TG 401 (Organisation for Economic Co-operation and Development, LD50: > 2 000 mg.kg-1 Result: the notified chemical is of low acute oral toxicity in rats 9.1.2 Dermal Toxicity (Tuffnell, 1992b) Species/strain: rat/Sprague-Dawley Number/sex of animals: 5/sex Observation period: 14 days Method of administration: dose of 2 000 mg.kg-1 of the notified chemical was applied to an area of shaved skin for 24 hours under an occlusive dressing Clinical observations: no signs of systemic toxicity were observed; desquamation was noted at the treatment sites of four females three to six days after dosing and persisted in two females seven days after dosing Mortality: nil Morphological findings: nil Test method: similar to OECD TG 402 (Organisation for Economic Co-operation and Development, LD50: > 2 000 mg.kg-1 Result: the notified chemical is of low acute toxicity when applied dermally to rats 9.1.3 Inhalation Toxicity No study was provided by the notifier. 9.1.4 Skin Irritation (Tuffnell, 1992c) Species/strain: rabbit/New Zealand White