The membrane attack unit begins when? C6 to C5b C6 does what when it binds to C5b? It stabilizes it What attaches to the cell surface? The complex What binds to C5b6 forming a trimolecular C7 complex that has a high affinity for lipid constituents of the cell membrane? What allows for insertion of the C7 part of the The binding of C7 C5b67 complex into the membrane of the target cell? What binds to C7 and exposes a hydrophobic C8 region that interacts with the cell membrane to form a small hole in the membrane? Which protein is inserted into the lipid bilayer? C8 Lysis can be observed after which protein C8 binds? Which protein accelerates the lysis process? C9 Binding of C8 causes a loss of what from the potassium cell? What follows the leakage of potassium from the The leakage of amino acids and ribonucleotides cell? What polymerizes only when bound, and it is C9 believed that the C5–C8 complex acts as a catalyst to enhance the rate of reaction? What a hollow, thin-walled cylinder, which Polymerized C9 constitutes the transmembrane channel? Pathogens can be destroyed in the absence of the alternative pathway antibody in which pathway? pathway acts as part of innate or natural the alternative pathway immunity? Which pathway was originally named for the the alternative pathway protein properdin? What does not initiate this pathway but rather Properdin stabilizes the C3 convertase formed from activation of other factors? The alternative pathway does not involve which C2 and C4 proteins? Which pathway has to get to C3 without going the alternative pathway through C2 and no C4 and without antibodies? Some Ag’s, like LPS, directly trigger a little of C3 which protein to be cleaved? Which protein is unstable, and is the pivotal C3 molecule to activate? What protein acts on factor B? C3b What acts on Bb to create C3Bb? Factor D What binds to host cells to prevent lysis and Factor H inhibits C3 activation?
The membrane attack unit begins when? C6 to C5b C6 does what when it binds to C5b? It stabilizes it What attaches to the cell surface? The complex What binds to C5b6 forming a trimolecular complex that has a high affinity for lipid constituents of the cell membrane? C7 What allows for insertion of the C7 part of the C5b67 complex into the membrane of the target cell? The binding of C7 What binds to C7 and exposes a hydrophobic region that interacts with the cell membrane to form a small hole in the membrane? C8 Which protein is inserted into the lipid bilayer? C8 Lysis can be observed after which protein binds? C8 Which protein accelerates the lysis process? C9 Binding of C8 causes a loss of what from the cell? potassium What follows the leakage of potassium from the cell? The leakage of amino acids and ribonucleotides What polymerizes only when bound, and it is believed that the C5–C8 complex acts as a catalyst to enhance the rate of reaction? C9 What a hollow, thin-walled cylinder, which constitutes the transmembrane channel? Polymerized C9 Pathogens can be destroyed in the absence of antibody in which pathway? the alternative pathway pathway acts as part of innate or natural immunity? the alternative pathway Which pathway was originally named for the protein properdin? the alternative pathway What does not initiate this pathway but rather stabilizes the C3 convertase formed from activation of other factors? Properdin The alternative pathway does not involve which proteins? C2 and C4 Which pathway has to get to C3 without going through C2 and no C4 and without antibodies? the alternative pathway Some Ag’s, like LPS, directly trigger a little of which protein to be cleaved? C3 Which protein is unstable, and is the pivotal molecule to activate? C3 What protein acts on factor B? C3b What acts on Bb to create C3Bb? Factor D What binds to host cells to prevent lysis and inhibits C3 activation? Factor H