rabbits; no erythema or oedema was observed in any animal at any time point Eye Irritation (Gardner, 1990; Gardner, 1992) Shell Brake Fluid Dot 4 rabbit/New Zealand Species/strain: 3/sex Number/sex of animals: 72 hours Observation period: 0.1 mL of undiluted test substance into the lower Method of administration: conjunctival sac of one eye of each animal EEC Method B5 Test method: the notified chemical was a slight eye irritant Result: in rabbits no corneal or iridal effects were observed; slight conjunctival redness was observed in 5 rabbits from 1 24 hours and in the 6th animal also at 48 hours; – slight chemosis was observed in 4 rabbits at 1 and 4 hours, in 2 rabbits at 4 hours only and slight discharge occurred in 2 rabbits at 1 and 4 hours and in 1 rabbit at 4 hours only Shell Brake Fluid Dot 4 Super rabbit/New Zealand White Species/strain: 3/sex Number/sex of animals: 72 hours Observation period: 0.1 mL of undiluted test substance into the lower Method of administration: conjunctival sac of one eye of each animal OECD TG 405 Test method: the notified chemical was a slight eye irritant Result: in rabbits no corneal or iridal effects were observed; slight conjunctival redness was observed in all rabbits at
rabbits; no erythema or oedema was observed in any animal at any time point Eye Irritation (Gardner, 1990; Gardner, 1992) Shell Brake Fluid Dot 4 Species/strain: rabbit/New Zealand Number/sex of animals: 3/sex Observation period: 72 hours Method of administration: 0.1 mL of undiluted test substance into the lower conjunctival sac of one eye of each animal Test method: EEC Method B5 Result: the notified chemical was a slight eye irritant in rabbits no corneal or iridal effects were observed; slight conjunctival redness was observed in 5 rabbits from 1 – 24 hours and in the 6th animal also at 48 hours; slight chemosis was observed in 4 rabbits at 1 and 4 hours, in 2 rabbits at 4 hours only and slight discharge occurred in 2 rabbits at 1 and 4 hours and in 1 rabbit at 4 hours only Shell Brake Fluid Dot 4 Super Species/strain: rabbit/New Zealand White Number/sex of animals: 3/sex Observation period: 72 hours Method of administration: 0.1 mL of undiluted test substance into the lower conjunctival sac of one eye of each animal Test method: OECD TG 405 Result: the notified chemical was a slight eye irritant in rabbits no corneal or iridal effects were observed; slight conjunctival redness was observed in all rabbits at