(Lapierre et al. Fluoxetine 35 ± 8 No 6 T6 62 64.5 40.2± 10.7 No 11 10 Yes 1997)() (Learned et al. Venlafaxine XR 150-225 No 10 T10 133 39 43.0± 11.2 No 11 7 Yes (study 1) Placebo 126 37 41.9± 11.8 7 3 2012)() (Learned et al. Paroxetine 20-30 No 10 T10 166 33 44.4± 10.9 No 7 - Yes (study 2) Placebo 156 39 41.8± 10.9 8 - 2012)() (Lee et al. Fluoxetine 40 Yes 6 T6 31 74.2 51 ± 12 No 2 - Yes 2005)() Milnacipran 100 39 69.2 49 ± 15 0 - (Lee et al. Duloxetine 60 Yes 8 T8 237 65.5 39.0± 13.9 No - 27 Yes 2007)() Paroxetine 20 239 73.8 38.0± 15.2 - 27 (Lemoine et al. Agomelatine 25-50 No 6 T6 166 75.2 40.7± 10.7 No 1 7 Yes 2007)() Venlafaxine 75-150 168 67.1 39.6± 10.3 4 8 (Lenox-Smith Citalopram 51 Yes 12 T12 205 64.1 43±11.2 No 15 - No et al. 2008)() Venlafaxine 191 199 69 42±10.8 9 - (Lepola et al. Citalopram 28.4 Yes 8 T8 160 69.4 44±11 No 7 5 Yes 2003)() Escitalopram 14.0 155 74.8 43±11 10 8 Placebo 154 72.1 43±12 3 2 (Lieberman et Venlafaxine 75-150 No 8 T8 127 72 46±12 GAD,DAP, - 12 Yes al. 2008)() social anxiety Venlafaxine 150-225 117 70 42±12 - 22 disorder Desvenlafaxine 200-400 231 68 43±12 - 31 Placebo 245 65 42±12 - 16
(Lapierre et al. 1997)() Fluoxetine 35 ± 8 No 6 T6 62 64.5 40.2± 10.7 No 11 10 Yes (Learned et al. (study 1) 2012)() Venlafaxine XR Placebo 150-225 No 10 T10 133 126 39 37 43.0± 11.2 41.9± 11.8 No 11 7 7 3 Yes (Learned et al. (study 2) 2012)() Paroxetine Placebo 20-30 No 10 T10 166 156 33 39 44.4± 10.9 41.8± 10.9 No 7 8 - - Yes (Lee et al. 2005)() Fluoxetine Milnacipran 40 100 Yes 6 T6 31 39 74.2 69.2 51 ± 12 49 ± 15 No 2 0 - - Yes (Lee et al. 2007)() Duloxetine Paroxetine 60 20 Yes 8 T8 237 239 65.5 73.8 39.0± 13.9 38.0± 15.2 No - - 27 27 Yes (Lemoine et al. 2007)() Agomelatine Venlafaxine 25-50 75-150 No 6 T6 166 168 75.2 67.1 40.7± 10.7 39.6± 10.3 No 1 4 7 8 Yes (Lenox-Smith et al. 2008)() Citalopram Venlafaxine 51 191 Yes 12 T12 205 199 64.1 69 43±11.2 42±10.8 No 15 9 - - No (Lepola et al. 2003)() Citalopram Escitalopram Placebo 28.4 14.0 Yes 8 T8 160 155 154 69.4 74.8 72.1 44±11 43±11 43±12 No 7 10 3 5 8 2 Yes (Lieberman et al. 2008)() Venlafaxine Venlafaxine Desvenlafaxine Placebo 75-150 150-225 200-400 No 8 T8 127 117 231 245 72 70 68 65 46±12 42±12 43±12 42±12 GAD,DAP, social anxiety disorder - - - - 12 22 31 16 Yes