Anatomical Site (ACIP and the AAFP recommendations for intramuscular injections) For adults (persons 18 years of age and older) the deltoid muscle is recommended for routine intramuscular vaccinations. The suggested needle size is 1-1½ inches and 22-25 gauge. Precautions See precautions in package insert Latex allergy See WARNINGS in package insert for information about any latex – components in the prefilled syringes being used. The vial stopper is latex-free. It is not known whether the vaccine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. This vaccine should only be given to a pregnant woman only if clearly indicated. It is not known whether this vaccine is excreted in human milk, caution should be exercised when administered to a nursing woman. As with intramuscular injections, use with caution in patients on anticoagulant therapy Contraindications Individuals with: Allergy to vaccine components Allergy to Neomycin sulfate Allergy to protein Anaphylactic reaction to the vaccine or a constituent of the vaccine Acute, moderate or severe illness with or without fever Adverse Events See the product’s package insert See Adverse Events Following Vaccinations page of this section Storage and Handling Store in refrigerator at 36oF 46oF (2oC 8oC) – – DO NOT FREEZE; discard if product has been frozen. Important Notes If administered concomitantly with immune globulin (IG), use a separate syringe and different site. Postexposure prophylaxis (PEP) during hepatitis A outbreaks or as part of a contact investigation. TWINRIX vaccine should not be used for hepatitis A PEP. Use single antigen hepatitis A vaccine for hepatitis A PEP, when hepatitis A vaccine is indicated. See the Hepatitis A vaccine protocol for additional details. Last updated January 31, 2010 and August 1, 2012
Anatomical Site (ACIP and the AAFP recommendations for intramuscular injections) For adults (persons 18 years of age and older) the deltoid muscle is recommended for routine intramuscular vaccinations. The suggested needle size is 1-1½ inches and 22-25 gauge. Precautions See precautions in package insert Latex allergy – See WARNINGS in package insert for information about any latex components in the prefilled syringes being used. The vial stopper is latex-free. It is not known whether the vaccine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. This vaccine should only be given to a pregnant woman only if clearly indicated. It is not known whether this vaccine is excreted in human milk, caution should be exercised when administered to a nursing woman. As with intramuscular injections, use with caution in patients on anticoagulant therapy Contraindications Individuals with: Allergy to vaccine components Allergy to Neomycin sulfate Allergy to protein Anaphylactic reaction to the vaccine or a constituent of the vaccine Acute, moderate or severe illness with or without fever Adverse Events See the product’s package insert See Adverse Events Following Vaccinations page of this section Storage and Handling Store in refrigerator at 36oF – 46oF (2oC – 8oC) DO NOT FREEZE; discard if product has been frozen. Important Notes If administered concomitantly with immune globulin (IG), use a separate syringe and different site. Postexposure prophylaxis (PEP) during hepatitis A outbreaks or as part of a contact investigation. TWINRIX vaccine should not be used for hepatitis A PEP. Use single antigen hepatitis A vaccine for hepatitis A PEP, when hepatitis A vaccine is indicated. See the Hepatitis A vaccine protocol for additional details. Last updated January 31, 2010 and August 1, 2012