Common abbreviations Abbreviation Meaning ACR20 American College of Rheumatology response 20% improvement ≥ American College of Rheumatology response 50% improvement ≥ ACR70 American College of Rheumatology response 70% improvement ≥ ACSOM Advisory Committee on the Safety of Medicines ADA Anti-drug antibody ADCC Antibody dependent cell mediated cytotoxicity AE Adverse event ALT Alanine transaminase AST Aspartate transaminase AUC Area under the curve AUCinf Area under the curve from time zero to infinity AUClast Area under the curve up to last measurable concentration CCF Cell culture fluid CDC Complement-dependent cytotoxicity CEX Cation Exchange chromatography CI Confidence interval Cmax Maximum plasma concentration CMI Consumer Medicines Information
Common abbreviations Abbreviation Meaning ACR20 American College of Rheumatology response ≥ 20% improvement American College of Rheumatology response ≥ 50% improvement ACR70 American College of Rheumatology response ≥ 70% improvement ACSOM Advisory Committee on the Safety of Medicines ADA Anti-drug antibody ADCC Antibody dependent cell mediated cytotoxicity AE Adverse event ALT Alanine transaminase AST Aspartate transaminase AUC Area under the curve AUCinf Area under the curve from time zero to infinity AUClast Area under the curve up to last measurable concentration CCF Cell culture fluid CDC Complement-dependent cytotoxicity CEX Cation Exchange chromatography CI Confidence interval Cmax Maximum plasma concentration CMI Consumer Medicines Information