Where is Transferrin in the body synthesized synthesized primarily in the liver and usually and how it migrates in electrophoresis? migrates in the on routine clinical β1-region electrophoresis of serum What is relationship between Transferrin and plasma concentrations are inversely related to iron concentration? iron concentration What is concentration of Transferrin and iron concentration is normal in hereditary saturation in hereditary hemochromatosis hemochromatosis (iron-overload state), but (iron-overload state)? iron saturation often exceeds 55% What is diurnal cycle for Transferrin? serum iron concentration usually is highest in the morning and decreases markedly in the evening What is level of Transferrin in pregnancy and high concentrations are present in pregnancy inflammation? and during estrogen administration is a negative APP, and low concentrations occur in inflammation and malignancy What is the of synthesis of Transferrin in Decreases following diseases? chronic liver disease, protein malnutrition, protein loss as seen in nephrotic syndrome or in protein-losing enteropathy What are laboratory considerations for Serum electrophoresis Transferrin determination? Immunoturbidimetry and Immunonephelometry methods Photometric assays for TIBC (Total Iron Binding Capacity) What is the formula for TIBC (Total Iron TIBC = UIBC + Iron Binding Capacity)? Where: TIBC = total iron binding capacity UIBC = unsaturated binding capacity Transferrin (TRF) migrates in…………on β1 –region routine electrophoresis. What is equation which TIBC is used to TRF (mg/dL) = 0.70 x TIBC (µg/dL) estimate TRF? or Iron % Transferrin saturation = --------------- x 100 TIBC What Low-Density Lipoprotein is termed on β-lipoprotein the of its electrophoretic mobility? What percentage of LDL is lipid? 80% What percentage of LDL is protein? 20% What is the main lipid component of LDL? cholesterol ester What is the main protein component of LDL? apolipoprotein B Increase in LDL concentration confer cardiovascular disease increased risk of ……………..? How concentration of LDL are assessed? assessed by calculation of LDL cholesterol that are based on other lipid measurements,
Where is Transferrin in the body synthesized and how it migrates in electrophoresis? synthesized primarily in the liver and usually migrates in the β1-region on routine clinical electrophoresis of serum What is relationship between Transferrin and iron concentration? plasma concentrations are inversely related to iron concentration What is concentration of Transferrin and iron saturation in hereditary hemochromatosis (iron-overload state)? concentration is normal in hereditary hemochromatosis (iron-overload state), but iron saturation often exceeds 55% What is diurnal cycle for Transferrin? serum iron concentration usually is highest in the morning and decreases markedly in the evening What is level of Transferrin in pregnancy and inflammation? high concentrations are present in pregnancy and during estrogen administration is a negative APP, and low concentrations occur in inflammation and malignancy What is the of synthesis of Transferrin in following diseases? chronic liver disease, protein malnutrition, protein loss as seen in nephrotic syndrome or in protein-losing enteropathy Decreases What are laboratory considerations for Transferrin determination? Serum electrophoresis Immunoturbidimetry and Immunonephelometry methods Photometric assays for TIBC (Total Iron Binding Capacity) What is the formula for TIBC (Total Iron Binding Capacity)? TIBC = UIBC + Iron Where: TIBC = total iron binding capacity UIBC = unsaturated binding capacity Transferrin (TRF) migrates in…………on routine electrophoresis. β1 –region What is equation which TIBC is used to estimate TRF? TRF (mg/dL) = 0.70 x TIBC (µg/dL) or Iron % Transferrin saturation = --------------- x 100 TIBC What Low-Density Lipoprotein is termed on the of its electrophoretic mobility? β-lipoprotein What percentage of LDL is lipid? 80% What percentage of LDL is protein? 20% What is the main lipid component of LDL? cholesterol ester What is the main protein component of LDL? apolipoprotein B Increase in LDL concentration confer increased risk of ……………..? cardiovascular disease How concentration of LDL are assessed? assessed by calculation of LDL cholesterol that are based on other lipid measurements,