(mmHg) PBS 47.1 [39.6-48.1] 7.158 [7.065-7.160] WT-MSCs 46.2 [43.3-49.8] 7.065 [7.003-7.097] PTX3-/--MSCs 50.6 [46.1-53.2] 7.134 [7.109-7.172] P-value 0.21 0.05 Kruskal Wallis Additional file 1: Table S2. Measures of lung edema, broncho-alveolar lavage (BAL) cells and OH-Proline content in the right vs. left lung in wild-type mice with acid aspiration acute lung injury. Wild type mice with acid aspiration acute lung injury 24 hours 2 weeks Wet to dry lung weight Total BAL cells count Total BAL PMNs OH-Pro content ratio (cells/µl) count (µg/g lung) (cells/µl) Treatment Right lung Left lung Right Left Right Left Right Left 270# 148 158# 31 PBS 6.00* ± 0.55 4.81 ± 0.44 857* ± 319 656 ± 236 [228-328] [133-260] [122-213] [22-146] 149 104 68# 37 5.60* ± 0.50 4.56 ± 0.25 613 ± 196 649 ± 262 WT-MSCs [106-190] [84-139] [53-109] [24-68] 220 202 108 57 PTX3-/--MSCs 5.72* ± 0.65 4.64 ± 0.35 698 ± 274 645 ± 356 [166-269] [138-297] [72-174] [22-186] * T-test: p<0.05 vs. Left # Mann-Whitney U test: p<0.05 vs. Left Additional file 1: Table S3. Oxygenation, lung edema and collagen deposition in PTX3-/- mice with acid aspiration acute lung injury treated by PBS and or PTX3-/--MSCs.
(mmHg) PBS 47.1 [39.6-48.1] 7.158 [7.065-7.160] WT-MSCs 46.2 [43.3-49.8] 7.065 [7.003-7.097] PTX3-/--MSCs 50.6 [46.1-53.2] 7.134 [7.109-7.172] P-value Kruskal Wallis 0.21 0.05 Additional file 1: Table S2. Measures of lung edema, broncho-alveolar lavage (BAL) cells and OH-Proline content in the right vs. left lung in wild-type mice with acid aspiration acute lung injury. Treatment Wild type mice with acid aspiration acute lung injury 24 hours 2 weeks Wet to dry lung weight ratio Total BAL cells count (cells/µl) Total BAL PMNs count (cells/µl) OH-Pro content (µg/g lung) Right lung Left lung Right Left Right Left Right Left PBS 6.00* ± 0.55 4.81 ± 0.44 270# [228-328] 148 [133-260] 158# [122-213] 31 [22-146] 857* ± 319 656 ± 236 WT-MSCs 5.60* ± 0.50 4.56 ± 0.25 149 [106-190] 104 [84-139] 68# [53-109] 37 [24-68] 613 ± 196 649 ± 262 PTX3-/--MSCs 5.72* ± 0.65 4.64 ± 0.35 220 [166-269] 202 [138-297] 108 [72-174] 57 [22-186] 698 ± 274 645 ± 356 * T-test: p<0.05 vs. Left # Mann-Whitney U test: p<0.05 vs. Left Additional file 1: Table S3. Oxygenation, lung edema and collagen deposition in PTX3-/- mice with acid aspiration acute lung injury treated by PBS and or PTX3-/--MSCs.