total physical activity, use of HRT, vegetable intake Age, sex, area of vs ≥32.8 ≤16.7 0.60 (0.33-1.07) residence, BMI, ng/ml 229/ Incidence, MEC, family history of 434 controls colorectal cancer per 2 ngml 0.71 (0.53-0.95) Nested Case colon cancer, Woolcott, 2010 Cancer registry Control, Unit converted fasting per 2 ngml 0.68 (0.51-0.92) COL40799 and national Dietary recall Age: 45-75 to nmol/l condition, USA Index 170/ Incidence, years, processed meat, per 2 ngml 0.79 (0.56-1.10) 319 controls cancer M/W race, time, year of birth 43/ Incidence, rectal per 2 ngml 0.40 (0.19-0.85) Calcium intake 83 controls cancer 163/ Incidence, vs ≥32.1 ≤22.8 324 controls colorectal 0.73 (0.35-1.50) ng/ml 11.5 years cancer, men JPHC, Incidence, Nested Case 160/ vs Otani, 2007 Cancer ≥27 registry ≤18.6 colorectal cancer 1.10 (0.50-2.30) Control, 297 controls ng/ml COL40672 and death FFQ Age: 40-69 Japan certificates years, 119/ Incidence, colon vs ≥32.1 ≤22.8 1.20 (0.51-2.70) M/W 237 controls cancer, men ng/ml 106/ Incidence, colon vs ≥27 ≤18.6 2.10 (0.78-5.60) 195 controls cancer, women ng/ml
total physical activity, use of HRT, vegetable intake Woolcott, 2010 COL40799 USA MEC, Nested Case Control, Age: 45-75 years, M/W 229/ 434 controls Cancer registry and national Index Dietary recall Incidence, colorectal cancer ≥32.8 vs ≤16.7 ng/ml 0.60 (0.33-1.07) Age, sex, area of residence, BMI, family history of colon cancer, fasting condition, processed meat, race, time, year of birth Calcium intake Unit converted to nmol/l per 2 ngml 0.71 (0.53-0.95) per 2 ngml 0.68 (0.51-0.92) 170/ 319 controls Incidence, cancer per 2 ngml 0.79 (0.56-1.10) 43/ 83 controls Incidence, rectal cancer per 2 ngml 0.40 (0.19-0.85) Otani, 2007 COL40672 Japan JPHC, Nested Case Control, Age: 40-69 years, M/W 163/ 324 controls 11.5 years Cancer registry and death certificates FFQ Incidence, colorectal cancer, men ≥32.1 vs ≤22.8 ng/ml 0.73 (0.35-1.50) 160/ 297 controls Incidence, colorectal cancer ≥27 vs ≤18.6 ng/ml 1.10 (0.50-2.30) 119/ 237 controls Incidence, colon cancer, men ≥32.1 vs ≤22.8 ng/ml 1.20 (0.51-2.70) 106/ 195 controls Incidence, colon cancer, women ≥27 vs ≤18.6 ng/ml 2.10 (0.78-5.60)