Table 308 Recreational physical activity and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR meta-analysis Cases/ Author, Year, Study name, Study size Case Exposure RR (95%CI) Adjustment Reasons for WCRF Code, Outcome Comparison characteristics Follow-up ascertainment assessment Ptrend factors exclusion Country (years) Batty, 2010 Whitehall Study, 104/ NHS central Questionnaire Mortality, Age, BMI, job Inactive vs active 1.00 (0.64-1.8) Outcome is COL40838 Prospective 6 928 registry colon cancer classification, mortality, UK Cohort, 40 years forced Mortality, insufficient Age: 40-69 expiratory rectal cancer number of years, Inactive vs active 1.80 (0.79-4.12) volume in 1 studies M, second, smoking Employed men Yun, 2008 1 827/ Cancer registry Self-report Incidence, Age, BMI, COL40946 Prospective 444 963 colorectal dietary Outcome is Korea Cohort, 6 years cancer preference, colorectal cancer Age: 40- years, moderate-high vs employment, 0.98 (0.90-1.08) not enough M low fasting studies to update sugar, smoking analysis status, alcohol drinking Age, alcohol Wolin, 2007 The Nurses's 302/ Follow up Questionnaire Incidence, intake, aspirin COL40700 Health Study 79 295 questionnaires; proximal vs ≥21.5 ≤2 0.97 (0.68-1.38) use, BMI, USA Cohort, 1 230 354 medical records; colon cancer hours/week calcium intake, Prospective person-years pathology family history of Cohort, reports; national 245/ Incidence, colon cancer, Age: 40-65 death index vs ≥21.5 ≤2 Superseded by distal colon 0.54 (0.34-0.84) history of years, Wei, 2009 cancer endoscopy, W, history of nurses 547/ Incidence, polyps, colon cancer vs 2.1-4.5 ≥21.5 multivitamin 0.77 (0.58-1.01) met-hours/week use, red meat intake, smoking
Table 308 Recreational physical activity and colorectal cancer risk. Main characteristics of studies excluded from the CUP SLR meta-analysis Author, Year, WCRF Code, Country Study name, characteristics Cases/ Study size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Reasons for exclusion Batty, 2010 COL40838 UK Whitehall Study, Prospective Cohort, Age: 40-69 years, M, Employed men 104/ 6 928 40 years NHS central registry Questionnaire Mortality, colon cancer Inactive vs active 1.00 (0.64-1.8) Age, BMI, job classification, forced expiratory volume in 1 second, smoking Outcome is mortality, insufficient number of studies Mortality, rectal cancer Inactive vs active 1.80 (0.79-4.12) Yun, 2008 COL40946 Korea Prospective Cohort, Age: 40- years, M 1 827/ 444 963 6 years Cancer registry Self-report Incidence, colorectal cancer moderate-high vs low 0.98 (0.90-1.08) Age, BMI, dietary preference, employment, fasting sugar, smoking status, alcohol drinking Outcome is colorectal cancer not enough studies to update analysis Wolin, 2007 COL40700 USA The Nurses's Health Study Cohort, Prospective Cohort, Age: 40-65 years, W, nurses 302/ 79 295 1 230 354 person-years Follow up questionnaires; medical records; pathology reports; national death index Questionnaire Incidence, proximal colon cancer ≥21.5 vs ≤2 0.97 (0.68-1.38) Age, alcohol intake, aspirin use, BMI, calcium intake, family history of colon cancer, history of endoscopy, history of polyps, multivitamin use, red meat intake, smoking Superseded by Wei, 2009 245/ Incidence, distal colon cancer ≥21.5 vs ≤2 0.54 (0.34-0.84) 547/ Incidence, colon cancer ≥21.5 vs 2.1-4.5 met-hours/week 0.77 (0.58-1.01) hours/week