What were the contributions of Meischer, Griffith, Chagraff, Luria et. al., Franklin, and Watson & to the understanding of DNA technology and molecular structure? What is the definition of DNA replication? How do the rules of directionality (3’ to 5” or 3’ to 5’) and semi-conservative replication apply to DNA replication? Who are the key enzyme players and roles in DNA replication? Describe the process of DNA replication? Describe the DOGMA” of molecular biology. “CENTRAL What is meant by a code” and what are the or codes “triplet “special” “specific” in DNA? Why is the DNA genetic codes redundant in the specification for some amino acids in a protein and yet not for other amino acids? What is the definition of DNA transcription and RNA translation? What is the process (steps) and who are the key players in transcription of DNA? What are the suspected roles of intron and exon sequences within the DNA? is the process (steps) are the key players in translation of RNA? What and who Which are the key organelles involved in protein synthesis for intracellular vs. extracellular protein? Molecular Biology Introduction I. A. History 1. Johannes Meischer 2. Frederick Griffith 3. Edwin Chagraff 4. Salvador Luria, Max Delbruck, Alfred Hershey & Martha Chase 5. Rosalind Franklin 6. James Watson & Francis Crick DNA Replication II. A. Definition and When? B. Rules 1. Directional 2. Semi-conservative C. Process by Enzyme Players
What were the contributions of Meischer, Griffith, Chagraff, Luria et. al., Franklin, and Watson & to the understanding of DNA technology and molecular structure? What is the definition of DNA replication? How do the rules of directionality (3’ to 5” or 3’ to 5’) and semi-conservative replication apply to DNA replication? Who are the key enzyme players and roles in DNA replication? Describe the process of DNA replication? Describe the “CENTRAL DOGMA” of molecular biology. What is meant by a “triplet code” and what are the “special” or “specific” codes in DNA? Why is the DNA genetic codes redundant in the specification for some amino acids in a protein and yet not for other amino acids? What is the definition of DNA transcription and RNA translation? What is the process (steps) and who are the key players in transcription of DNA? What are the suspected roles of intron and exon sequences within the DNA? What is the process (steps) and who are the key players in translation of RNA? Which are the key organelles involved in protein synthesis for intracellular vs. extracellular protein? Molecular Biology I. Introduction A. History 1. Johannes Meischer 2. Frederick Griffith 3. Edwin Chagraff 4. Salvador Luria, Max Delbruck, Alfred Hershey & Martha Chase 5. Rosalind Franklin 6. James Watson & Francis Crick II. DNA Replication A. Definition and When? B. Rules 1. Directional 2. Semi-conservative C. Process by Enzyme Players