North Caroline Central Cancer Registry Pancreatic () Total TFA Country: Netherlands Dietary gender, age, TEI, No intake of TFA Intake: No assoc. TFA NLCS assessment: smoking, & pancreatic cancer in and pancreatic cancer Pancreatic N=120 852, 48% M Self-administered alcohol, T2D, the total population in risk cancer risk & Age: 61.7 (55-69)y validated 150 HTN, BMI, age and gender Prospective fat intake 13y FU item FFQ Vegetables, adjusted & 350 incident cases Database multivariable TRANSFAIR study adjusted. TFA intake: (g/day) 2.91±1.241 Outcome dx: vs quintiles of ↑ ↓ Netherlands intake: Cancer Registry & RR 1.14 (0.79-1.64) Netherlands Pathology Registry () Total TFA Country: US Dietary Smoking, BMI, vs quintile of TFA Intake: No assoc. TTFA ↑ ↓ NHS assessment: Hx T2D, TEI, Ht. intake: and pancreatic cancer Pancreatic N=88 802 F 61 item SFFQ PAL, RR 0.91 (95%CI 0.58, risk Prospective cancer & diet Age: 46.8 (30-55)y 1980, menopausal 1.43) p=0.44 18y FU 131 item status, 178 dx glycaemic load ’84,’86,’90 TFA intake: median intake. g/day): Outcome dx: Q1=2.5, Q2=3.3, Self-reported via Q3=3.9, Q4=4.6, Medical Q5=5.7 records obtained for confirmation
North Caroline Central Cancer Registry Pancreatic () Prospective Total TFA Pancreatic cancer risk & fat intake Country: Netherlands NLCS N=120 852, 48% M Age: 61.7 (55-69)y 13y FU 350 incident cases TFA intake: (g/day) 2.91±1.241 Dietary assessment: Self-administered validated 150 item FFQ Database TRANSFAIR study Outcome dx: Netherlands Cancer Registry & Netherlands Pathology Registry gender, age, TEI, smoking, alcohol, T2D, HTN, BMI, Vegetables, No intake of TFA & pancreatic cancer in the total population in age and gender adjusted & multivariable adjusted. ↑ vs ↓ quintiles of intake: RR 1.14 (0.79-1.64) Intake: No assoc. TFA and pancreatic cancer risk () Prospective Total TFA Pancreatic cancer & diet Country: US NHS N=88 802 F Age: 46.8 (30-55)y 18y FU 178 dx TFA intake: median g/day): Q1=2.5, Q2=3.3, Q3=3.9, Q4=4.6, Q5=5.7 Dietary assessment: 61 item SFFQ 1980, 131 item ’84,’86,’90 Outcome dx: Self-reported via Medical records obtained for confirmation Smoking, BMI, Hx T2D, TEI, Ht. PAL, menopausal status, glycaemic load intake. ↑ vs ↓ quintile of TFA intake: RR 0.91 (95%CI 0.58, 1.43) p=0.44 Intake: No assoc. TTFA and pancreatic cancer risk