activity, processed meat, smoking, vitamin d Meng, 2013 HPFS, 1 029/ Questionnaire Incidence, 1.00 (0.71-1.42) COL40931 Prospective 45 592 colorectal cancer Age, aspirin use, Ptrend:0.89 USA Cohort, 22 years BMI, Age: 40-75 endoscopy, 811/ Incidence, colon 1.09 (0.76-1.58) years, family history of cancer Ptrend:0.90 M, colorectal Health 345/ Questionnaire Incidence, vs ≥1/day cancer, physical 1.35 (0.80-2.28) professionals proximal cancer <1/month activity, Ptrend:0.43 smoking Alcohol, beef, pork or lamb as 314/ Incidence, distal a main dish, cancer 1.01 (0.55, 1.86) calcium, energy, folate, processed meat, vitamin d 218/ Questionnaire Incidence, rectal vs 0.60 (0.22-1.66) ≥1/day cancer <1/month Ptrend:0.56 McCullough, CPS 1 130/ II, Incidence, Cancer registry FFQ 1.03 (0.77-1.37) 2012 Prospective 99 700 colorectal cancer 1+ vs and <1 death /month Ptrend:0.67 COL40919 Cohort, 7 years certificates and USA M/W medical records 579/ Men 1.10 (0.74-1.64) 1+ vs <1 /month Ptrend:0.26
activity, processed meat, smoking, vitamin d Meng, 2013 COL40931 USA HPFS, Prospective Cohort, Age: 40-75 years, M, Health professionals 1 029/ 45 592 22 years Questionnaire Incidence, colorectal cancer ≥1/day vs <1/month 1.00 (0.71-1.42) Ptrend:0.89 Age, aspirin use, BMI, endoscopy, family history of colorectal cancer, physical activity, smoking Alcohol, beef, pork or lamb as a main dish, calcium, energy, folate, processed meat, vitamin d 811/ Incidence, colon cancer 1.09 (0.76-1.58) Ptrend:0.90 345/ Questionnaire Incidence, proximal cancer 1.35 (0.80-2.28) Ptrend:0.43 314/ Incidence, distal cancer 1.01 (0.55, 1.86) 218/ Questionnaire Incidence, rectal cancer ≥1/day vs <1/month 0.60 (0.22-1.66) Ptrend:0.56 McCullough, 2012 COL40919 USA CPS II, Prospective Cohort, M/W 1 130/ 99 700 7 years Cancer registry and death certificates and medical records FFQ Incidence, colorectal cancer 1+ vs <1 /month 1.03 (0.77-1.37) Ptrend:0.67 579/ Men 1+ vs <1 /month 1.10 (0.74-1.64) Ptrend:0.26