Age: 45-74 registries and 35.45-46.25 vs activity, smoking status, years, 228/ death cert. Women 21.6-27.1 0.82 (0.56-1.21) total energy intake, area M/W mets/day 36.25-46.25 vs Incidence, rectal 162/ 21.6-27.1 0.88 (0.57-1.36) cancer, men mets/day 35.45-46.25 vs 86/ Women 21.6-27.1 1.79 (0.99-3.23) mets/day 290/ Incidence, 43.75 vs 28.25 65 022 colorectal 0.69 (0.49-0.97) 6 cancer, men JPHC Age, alcohol intake, 43.75 vs 28.5 I and II, Active patient 196/ 1.16 (0.76-1.77) BMI, folate intake, red met/hours/day Lee, 2007 Prospective notification from meat intake, smoking COL40644 Cohort, hospitals, cancer Incidence, colon 43.75 vs 28.5 habits, study area, 140/ 0.89 (0.54-1.49) Japan Age: 40-69 registries and questionnaire cancer, women met/hours/day family history of years, death cert. colorectal cancer, fibre Incidence, rectal 43.75 vs 28.25 M/W 93/ 1.06 (0.56-2.00) cancer, men met/hours/day 43.75 vs 28.5 56/ Women 2.23 (0.99-5.01) met/hours/day 243/ Self-report, Age, alcohol intake, Calton, 2006 Prospective 31 783 pathology Incidence, colon 65-98.1 vs aspirin use, BMI, COL40618 Questionnaire 1.15 (0.76-1.75) Cohort, 270 325 report, national cancer met hr/day calcium intake, USA W years death index, educational level,
years Age: 45-74 years, M/W registries and death cert. activity, smoking status, total energy intake, area 228/ Women 35.45-46.25 vs 21.6-27.1 mets/day 0.82 (0.56-1.21) 162/ Incidence, rectal cancer, men 36.25-46.25 vs 21.6-27.1 mets/day 0.88 (0.57-1.36) 86/ Women 35.45-46.25 vs 21.6-27.1 mets/day 1.79 (0.99-3.23) Lee, 2007 COL40644 Japan JPHC I and II, Prospective Cohort, Age: 40-69 years, M/W 290/ 65 022 6 Active patient notification from hospitals, cancer registries and death cert. questionnaire Incidence, colorectal cancer, men 43.75 vs 28.25 0.69 (0.49-0.97) Age, alcohol intake, BMI, folate intake, red meat intake, smoking habits, study area, family history of colorectal cancer, fibre 196/ 43.75 vs 28.5 met/hours/day 1.16 (0.76-1.77) 140/ Incidence, colon cancer, women 43.75 vs 28.5 met/hours/day 0.89 (0.54-1.49) 93/ Incidence, rectal cancer, men 43.75 vs 28.25 met/hours/day 1.06 (0.56-2.00) 56/ Women 43.75 vs 28.5 met/hours/day 2.23 (0.99-5.01) Calton, 2006 COL40618 USA Prospective Cohort, W 243/ 31 783 270 325 Self-report, pathology report, national death index, Questionnaire Incidence, colon cancer 65-98.1 vs met hr/day 1.15 (0.76-1.75) Age, alcohol intake, aspirin use, BMI, calcium intake, educational level,