Incidence, proximal colon 6-9 vs 0-2 points 0.84 (0.61-1.14) cancer, women Incidence, 56-88 vs 15-41 colorectal 0.71 (0.61-0.82) points cancer, men Incidence, 56-88 vs 13-41 proximal colon 0.75 (0.54-1.05) points cancer, women Incidence, distal 56-88 vs 15-41 colon cancer, 0.75 (0.75-0.96) points men Table WCRF score and colorectal cancer risk. Main characteristics of studies identified in the CUP SLR Cases/ Author, Year, Study name, Study size Case Exposure RR (95%CI) Adjustment WCRF Code, Outcome Comparison characteristics Follow-up ascertainment assessment Ptrend factors Country (years) Makarem, 2015 FHS-Offspring 63/ Death certificate Incidence, COL41060 Cohort, 2 983 and medical quantitative colorectal USA Prospective 11.5 years records FFQ cancer Age, sex, per 1 points 0.87 (0.68-1.12) Cohort, WCRF smoking status Age: 66 years, Score M/W Romaguera, EPIC, 3 880/ Cancer FFQ Incidence, per 1 points 0.88 (0.84-0.91) Age, sex,
Incidence, proximal colon cancer, women 6-9 vs 0-2 points 0.84 (0.61-1.14) Incidence, colorectal cancer, men 56-88 vs 15-41 points 0.71 (0.61-0.82) Incidence, proximal colon cancer, women 56-88 vs 13-41 points 0.75 (0.54-1.05) Incidence, distal colon cancer, men 56-88 vs 15-41 points 0.75 (0.75-0.96) Table WCRF score and colorectal cancer risk. Main characteristics of studies identified in the CUP SLR Author, Year, WCRF Code, Country Study name, characteristics Cases/ Study size Follow-up (years) Case ascertainment Exposure assessment Outcome Comparison RR (95%CI) Ptrend Adjustment factors Makarem, 2015 COL41060 USA FHS-Offspring Cohort, Prospective Cohort, Age: 66 years, M/W 63/ 2 983 11.5 years Death certificate and medical records FFQ WCRF Score Incidence, colorectal cancer per 1 points 0.87 (0.68-1.12) Age, sex, smoking status Romaguera, EPIC, 3 880/ Cancer FFQ Incidence, per 1 points 0.88 (0.84-0.91) Age, sex, quantitative