vitamin B12, vitamin B6, total energy intake, family history of colorectal cancer, multivitamin supplement use, physical activity, previous polyps, sigmoidoscopy, smoking status IWHS, McCarl, 2006 Prospective 954/ Superseded by Incidence, vs ≥634.61 COL40633 Cohort, 35 197 SEER registry FFQ 0.73 (0.59-0.89) Age Razzak, 2012 colorectal cancer mcg ≤231.78 USA Age: 55-69 15 years COL40928 W NHS, Nested Case Mean exposure Feskanich, 2004 193/ Medical records Incidence, of blood Control, only COL01680 383 controls and writing or FFQ colorectal (mean exposure) draw, year of Age: 46-78 Superseded by USA 11 years by telephone cancer, birth years, Wei, 2004 W NHS, Age, alcohol Self-reported Prospective 428/ Incidence, colon consumption, Superseded by Fuchs, 2002 verified by Cohort, 88 758 cancer, no vs aspirin use, Wei, 2004, ≥400 ≤200 COL00415 medical records FFQ 0.91 (0.69-1.19) Age: 30-55 1 375 165 family history of mcg/day beef, pork, or COL00581 and USA and National years, crc lamb, BMI, Kim, 2010 Death Index W, energy-adjusted
vitamin B12, vitamin B6, total energy intake, family history of colorectal cancer, multivitamin supplement use, physical activity, previous polyps, sigmoidoscopy, smoking status McCarl, 2006 COL40633 USA IWHS, Prospective Cohort, Age: 55-69 W 954/ 35 197 15 years SEER registry FFQ Incidence, colorectal cancer ≥634.61 vs ≤231.78 mcg 0.73 (0.59-0.89) Age Superseded by Razzak, 2012 COL40928 Feskanich, 2004 COL01680 USA NHS, Nested Case Control, Age: 46-78 years, W 193/ 383 controls 11 years Medical records and writing or by telephone FFQ Incidence, colorectal cancer, (mean exposure) of blood draw, year of birth Mean exposure only Superseded by Wei, 2004 Fuchs, 2002 COL00415 USA NHS, Prospective Cohort, Age: 30-55 years, W, 428/ 88 758 1 375 165 Self-reported verified by medical records and National Death Index FFQ Incidence, colon cancer, no family history of crc ≥400 vs ≤200 mcg/day 0.91 (0.69-1.19) Age, alcohol consumption, aspirin use, beef, pork, or lamb, BMI, energy-adjusted Superseded by Wei, 2004, COL00581 and Kim, 2010