Table 7 Appendix 6 Inclusion/exclusion table for meta-analysis of supplemental vitamin D and colorectal cancer WCRFCode Author Year Name Subgroup SLR CUP CUP H Estimated values Exclusion reason Study Cancer Design outcome dose- vs. L response forest plot COL40668 Park SY 2007 Men New No Yes Missing PY Prospective Hawaii-Los colorectal Cohort Angeles cancer Multiethnic Cohort (MEC) Study Women colorectal New No Yes Missing PY cancer COL01690 Lin 2005 Prospective Women's Health Women colorectal Yes (Dose; H. vs.L) No Yes Missing standard Cohort Study cancer deviation value COL00314 Jarvinen 2001 Prospective Finland, Social No colorectal Yes (H. vs L.) No Yes No information for a Cohort Insurance cancer dose-response analysis Institution's Mobile Clinic COL00209 1998 Reviewed in text No Yes (but Missing exposure Zheng W. Prospective Iowa Women's Women - post rectal et al Cohort Health Study menopausal cancer only result available) COL01974 Sellers TA 1998 Prospective Iowa Women - no family colon Reviewed in text No Yes Missing PY Cohort Health Study history of CRC cancer - family colon Reviewed in text No Yes Missing PY history of CRC cancer COL00156 Kearney J 1996 Prospective health Men colon Yes (Dose; H. vs.L) Yes Yes Mid-exposure values + PY per quantile professionals et Cohort cancer follow-up study COL00131 Martinez 1996 Prospective Nurses' Health Women colorectal Yes (H. vs.L) No Yes No information for a Cohort Study Cohort cancer dose-response analysis COL01450 Bostick 1993 Prospective Iowa Women's Women colon Yes (Dose; H. vs.L) Yes No Mid-exposure values + nb of and PY For H vs L, results from Cohort Health Study cancer not provided for the multivariate model Sellers 1998 are more ==>taken from the age-ajusted recent. model Total no. of Total no. of no. of Total no. Total no. articles = 8 individual cohort individual cohort of studies of studies studies = 6 studies included = included included 5 (3 & 5 in = 2 in = 4 in CRC/COL dose- COL CRC; 2 in response and H vs. COL; 1 in L meta-analysis REC respectively)
Table 7 Appendix 6 Inclusion/exclusion table for meta-analysis of supplemental vitamin D and colorectal cancer WCRFCode Author Year Study Design Name Subgroup Cancer outcome SLR CUP dose- response CUP H vs. L forest plot Estimated values Exclusion reason COL40668 Park SY 2007 Prospective Cohort Hawaii-Los Angeles Multiethnic Cohort (MEC) Study Men colorectal cancer New No Yes Missing PY Women colorectal cancer New No Yes Missing PY COL01690 Lin 2005 Prospective Cohort Women's Health Study Women colorectal cancer Yes (Dose; H. vs.L) No Yes Missing standard deviation value COL00314 Jarvinen 2001 Prospective Cohort Finland, Social Insurance Institution's Mobile Clinic No colorectal cancer Yes (H. vs L.) No Yes No information for a dose-response analysis COL00209 Zheng W. et al 1998 Prospective Cohort Iowa Women's Health Study Women - post menopausal rectal cancer Reviewed in text No Yes (but only result available) Missing exposure COL01974 Sellers TA 1998 Prospective Cohort Iowa Health Study Women - no family history of CRC colon cancer Reviewed in text No Yes Missing PY - family history of CRC colon cancer Reviewed in text No Yes Missing PY COL00156 Kearney J et 1996 Prospective Cohort health professionals follow-up study Men colon cancer Yes (Dose; H. vs.L) Yes Yes Mid-exposure values + PY per quantile COL00131 Martinez 1996 Prospective Cohort Nurses' Health Study Cohort Women colorectal cancer Yes (H. vs.L) No Yes No information for a dose-response analysis COL01450 Bostick 1993 Prospective Cohort Iowa Women's Health Study Women colon cancer Yes (Dose; H. vs.L) Yes No Mid-exposure values + nb of and PY not provided for the multivariate model ==>taken from the age-ajusted model For H vs L, results from Sellers 1998 are more recent. Total no. of articles = 8 Total no. of individual cohort studies = 6 no. of individual cohort studies included = 5 (3 & 5 in CRC/COL dose- response and H vs. L meta-analysis respectively) Total no. of studies included = 2 in COL Total no. of studies included = 4 in CRC; 2 in COL; 1 in REC