1 randomised not serious not serious not serious serious a none 22/137 (16.1%) 14/135 RR 1.55 57 more per 1,000 CRITICAL trials (10.4%) (0.83 to 2.90) (from 18 to 197 more) MODERATE Duration of mechanical ventilation (Days) 1 randomised not serious not serious not serious serious a none 137 135 - MD 0 IMPORTANT trials (2.63 lower to 2.63 higher) MODERATE ICU length of stay 1 randomised not serious not serious not serious serious a none 137 135 - MD 1 higher IMPORTANT trials (1.26 lower to 3.26 higher) MODERATE Proportion of days with delirium 1 randomised not serious not serious not serious serious a none 137 135 - MD 3 higher IMPORTANT trials (4.01 lower to 10.01 higher) MODERATE CI: Confidence interval; RR: Risk ratio; MD: Mean difference a. 95% CI embraces benefit and harm. Population: patients with delirium Background: Intervention: statins Comparison: placebo Main outcomes: Hospital Mortality Duration of mechanical ventilation (Days) ICU length of stay Proportion of days with delirium Setting: Intensive care unit Criteria Judgements Research evidence
1 randomised trials not serious not serious not serious serious a none 22/137 (16.1%) 14/135 (10.4%) RR 1.55 (0.83 to 2.90) 57 more per 1,000 (from 18 to 197 more) MODERATE CRITICAL Duration of mechanical ventilation (Days) 1 randomised trials not serious not serious not serious serious a none 137 135 - MD 0 (2.63 lower to 2.63 higher) MODERATE IMPORTANT ICU length of stay 1 randomised trials not serious not serious not serious serious a none 137 135 - MD 1 higher (1.26 lower to 3.26 higher) MODERATE IMPORTANT Proportion of days with delirium 1 randomised trials not serious not serious not serious serious a none 137 135 - MD 3 higher (4.01 lower to 10.01 higher) MODERATE IMPORTANT CI: Confidence interval; RR: Risk ratio; MD: Mean difference a. 95% CI embraces benefit and harm. Population: patients with delirium Background: Intervention: statins Comparison: placebo Main outcomes: Hospital Mortality Duration of mechanical ventilation (Days) ICU length of stay Proportion of days with delirium Setting: Intensive care unit Criteria Judgements Research evidence