Pulmonary 1 (5) 0 Pneumonitis 1 (5) 0 Renal 1 (5) 0 Creatinine increased 1 (5) 0 Tubulointerstitial nephritis 1 (5) 0 Skin 15 (71) 0 Rash 10 (48) 0 Pruritus 4 (19) 0 Skin hypopigmentation 2 (10) 0 Erythema 1 (5) 0 Erythematous rash 1 (5) 0 Exfoliative rash 1 (5) 0 Generalized rash 1 (5) 0 Macular rash 1 (5) 0 Papular rash 1 (5) 0 Pruritic rash 1 (5) 0 Skin exfoliation 1 (5) 0 Based on a September 2016 database lock. aNo grade 4 or 5 events were reported. AE, adverse event; ALT, alanine aminotransferase; AST, aspartate aminotransferase; NSCLC, non-small cell lung cancer.
Pulmonary Pneumonitis 1 (5) 1 (5) 0 0 Renal Creatinine increased Tubulointerstitial nephritis 1 (5) 1 (5) 1 (5) 0 0 0 Skin Rash Pruritus Skin hypopigmentation Erythema Erythematous rash Exfoliative rash Generalized rash Macular rash Papular rash Pruritic rash Skin exfoliation 15 (71) 10 (48) 4 (19) 2 (10) 1 (5) 1 (5) 1 (5) 1 (5) 1 (5) 1 (5) 1 (5) 1 (5) 0 0 0 0 0 0 0 0 0 0 0 0 Based on a September 2016 database lock. aNo grade 4 or 5 events were reported. AE, adverse event; ALT, alanine aminotransferase; AST, aspartate aminotransferase; NSCLC, non-small cell lung cancer.