2004 Prospective 38 451 colorectal cancer consumption, COL00299 Cohort, 7.9 years BMI, USA Age: 45- years, adjusted W, calcium, nurses adjusted folate, energy-adjusted total fat, adjusted vitamin d, energy total Ptrend:0.004 fibre, family history of specific cancer, history of oral contraceptive use, HRT use, NSAID use, physical activity, smoking habits, total energy Age, alcohol 2003 CNBSS, 616/ Breast cancer Quantitative Incidence, colon 0.95 (0.61-1.50) vs ≥185 ≤98 consumption, COL00561 Prospective 49 124 screening FFQ cancer Ptrend:0.49 BMI, Canada Cohort, 810 649 centres Incidence, 1.05 (0.73-1.53) educational Age: 40-59 vs ≥185 ≤98 colorectal cancer Ptrend:0.94 level, energy years, intake, folic acid W Incidence, rectal intake, hormone cancer replacement 1.34 (0.70-2.58) therapy, oral vs ≥185 ≤98 Ptrend:0.31 contraceptive use, parity, physical
2004 COL00299 USA Prospective Cohort, Age: 45- years, W, nurses 38 451 7.9 years colorectal cancer Ptrend:0.004 consumption, BMI, calcium, folate, energy-adjusted total fat, vitamin d, energy total fibre, family history of specific cancer, history of oral contraceptive use, HRT use, NSAID use, physical activity, smoking habits, total energy 2003 COL00561 Canada CNBSS, Prospective Cohort, Age: 40-59 years, W 616/ 49 124 810 649 Breast cancer screening centres Quantitative FFQ Incidence, colon cancer ≥185 vs ≤98 0.95 (0.61-1.50) Ptrend:0.49 Age, alcohol consumption, BMI, educational level, energy intake, folic acid intake, hormone replacement therapy, oral contraceptive use, parity, physical Incidence, colorectal cancer ≥185 vs ≤98 1.05 (0.73-1.53) Ptrend:0.94 Incidence, rectal cancer ≥185 vs ≤98 1.34 (0.70-2.58) Ptrend:0.31 adjusted adjusted adjusted