cancer, BMI Ptrend:0.12 0.52 (0.22-1.23) 76/ BMI < 25 vs ≥89.4 ≤80.9 Ptrend:0.16 3.34 56/ BMI >=30 vs ≥89.4 ≤80.9 Ptrend:0.02 4.22 No diabetes & 47/ vs ≥89.4 ≤80.9 BMI ≥30 Ptrend:0.01 Age, alcohol per 1 unit/day 1.05 (1.00-1.11) consumption, BMI, adjusted calcium, adjusted folate, energy-adjusted total fat, WHS, adjusted vitamin Higginbotham, Prospective 174/ d, energy 2004 Cohort, Incidence, 38 451 Cancer registry FFQ total 1.71 (0.98-2.98) COL00299 Age: 45- years, colorectal cancer 57 vs 49 7.9 years fibre, family USA W, Ptrend:0.04 history of nurses specific cancer, history of oral contraceptive use, HRT use, NSAID use, physical activity, smoking habits,
cancer, BMI Ptrend:0.12 76/ BMI < 25 ≥89.4 vs ≤80.9 0.52 (0.22-1.23) Ptrend:0.16 56/ BMI >=30 ≥89.4 vs ≤80.9 3.34 Ptrend:0.02 47/ No diabetes & BMI ≥30 ≥89.4 vs ≤80.9 4.22 Ptrend:0.01 Higginbotham, 2004 COL00299 USA WHS, Prospective Cohort, Age: 45- years, W, nurses 174/ 38 451 7.9 years Cancer registry FFQ Incidence, colorectal cancer per 1 unit/day 1.05 (1.00-1.11) Age, alcohol consumption, BMI, calcium, folate, energy-adjusted total fat, vitamin d, energy total fibre, family history of specific cancer, history of oral contraceptive use, HRT use, NSAID use, physical activity, smoking habits, 57 vs 49 1.71 (0.98-2.98) Ptrend:0.04 adjusted adjusted adjusted