10. Why is Oscar's endogenous circulating level of ACTH significantly elevated? 11. What is the cause of Oscar's hyperpigmentation? How is this related to his high levels of ACTH? 12. What type of replacement therapy be required for Oscar? Will the replacement of one hormone suffice to treat all his symptoms? 13. Diagram the feedback loops for this endocrine disorder. 14. What is the long-term outlook for Might one expect Oscar's abnormal pigmentation to resolve once his treatment has begun? Explain.
10. Why is Oscar's endogenous circulating level of ACTH significantly elevated? 11. What is the cause of Oscar's hyperpigmentation? How is this related to his high levels of ACTH? 12. What type of replacement therapy be required for Oscar? Will the replacement of one hormone suffice to treat all his symptoms? 13. Diagram the feedback loops for this endocrine disorder. 14. What is the long-term outlook for Might one expect Oscar's abnormal pigmentation to resolve once his treatment has begun? Explain.