Supplementary Fig. S1 Rarefaction analysis of bacterial 16S and fungal 28S rRNA gene sequences for the analysis of (A) bacterial and (B) fungal diversities in the interior (solid lines) and exterior (dotted lines) regions during the entire doenjang-meju fermentation process. The rarefaction analysis was carried out within the MOTHUR program with a 97% OTU cutoff value and numbers beside the curves represent the fermentation time (in days) of the meju samples. Supplementary Table S1 List of adapters, rRNA primers, and barcode sequences in the PCR primer sets used in this study. Name Sequence (5'-3') Reference Adapter sequence A adapter CCATCTCATCCCTGCGTGTCTCCGACTCAG Roesch et al., 2007 B adapter CCTATCCCCTGTGTGCCTTGGCAGTCTCAG Roesch et al., 2007 rRNA primers 9F GAGTTTGATCMTGGCTCAG DeLong, 1992 541R WTTACCGCGGCTGCTGG DeLong, 1992 LR0R ACCCGCTGAACTTAAGC Liu et al., 2012 LR3 AG-CCGTGTTTCAAGACGGG Liu et al., 2012 Bacteria (exterior) 1 TCGTCAT This study 7 AGAGCTG This study 14 TCAGATG This study 21 TATGCAC This study 28 TCTGCAG This study 35 ATGCTGAG This study 42 ATGCAGAC This 49 TAGCTACG This study 63 TGACTCTG This study Bacteria (Interior) 1 ACTACACGC This study 7 ACTGAGT This study 14 CGATGAG This study 21 TCATATACGCG This study 28 CGTGTACTG This study 35 TACAGCAG This 42 CATGTAGC This study 49 TCGAGTAG This 63 ACACTGTG This study Fungi (Exterior) 7 CTGTGAT This study
Supplementary Fig. S1 Rarefaction analysis of bacterial 16S and fungal 28S rRNA gene sequences for the analysis of (A) bacterial and (B) fungal diversities in the interior (solid lines) and exterior (dotted lines) regions during the entire doenjang-meju fermentation process. The rarefaction analysis was carried out within the MOTHUR program with a 97% OTU cutoff value and numbers beside the curves represent the fermentation time (in days) of the meju samples. Supplementary Table S1 List of adapters, rRNA primers, and barcode sequences in the PCR primer sets used in this study. Name Sequence (5'-3') Reference Adapter sequence A adapter CCATCTCATCCCTGCGTGTCTCCGACTCAG Roesch et al., 2007 B adapter CCTATCCCCTGTGTGCCTTGGCAGTCTCAG Roesch et al., 2007 rRNA primers 9F GAGTTTGATCMTGGCTCAG DeLong, 1992 541R WTTACCGCGGCTGCTGG DeLong, 1992 LR0R ACCCGCTGAACTTAAGC Liu et al., 2012 LR3 AG-CCGTGTTTCAAGACGGG Liu et al., 2012 Bacteria (exterior) 1 TCGTCAT This study 7 AGAGCTG This study 14 TCAGATG This study 21 TATGCAC This study 28 TCTGCAG This study 35 ATGCTGAG This study 42 ATGCAGAC This 49 TAGCTACG This study 63 TGACTCTG This study Bacteria (Interior) 1 ACTACACGC This study 7 ACTGAGT This study 14 CGATGAG This study 21 TCATATACGCG This study 28 CGTGTACTG This study 35 TACAGCAG This 42 CATGTAGC This study 49 TCGAGTAG This 63 ACACTGTG This study Fungi (Exterior) 7 CTGTGAT This study