1 0.7 0.79 1.9 – 1 0.6 0.69 1.6 – 1 0.5 0.59 1.4 – 1 0.4 0.49 1.1 – Expected Number of Volume of Blincyto vials Dose Cassette Duration BSA (m2) Reconstituted required* BLINCYTO 3 1.5 1.59 5.8 – 2 1.4 1.49 5.4 – 2 1.3 1.39 5 – 2 1.2 1.29 4.7 – 2 1.1 1.19 4.3 – 2 1 1.09 3.9 – 72 hours 2 0.9 0.99 3.5 – 2 0.8 0.89 3.2 – 1 0.7 0.79 2.8 – 1 0.6 0.69 2.4 – 1 0.5 0.59 2 – 1 0.4 0.49 1.7 – 3 1.5 1.59 7.7 – 3 1.4 1.49 7.2 – 96 hours 3 1.3 1.39 6.7 – 3 1.2 1.29 6.2 – 3 1.1 1.19 5.7 –
1 0.7 – 0.79 1.9 1 0.6 – 0.69 1.6 1 0.5 – 0.59 1.4 1 0.4 – 0.49 1.1 Dose Cassette Duration Expected Number of Blincyto vials required* BSA (m2) Volume of Reconstituted BLINCYTO 72 hours 3 1.5 – 1.59 5.8 2 1.4 – 1.49 5.4 2 1.3 – 1.39 5 2 1.2 – 1.29 4.7 2 1.1 – 1.19 4.3 2 1 – 1.09 3.9 2 0.9 – 0.99 3.5 2 0.8 – 0.89 3.2 1 0.7 – 0.79 2.8 1 0.6 – 0.69 2.4 1 0.5 – 0.59 2 1 0.4 – 0.49 1.7 96 hours 3 1.5 – 1.59 7.7 3 1.4 – 1.49 7.2 3 1.3 – 1.39 6.7 3 1.2 – 1.29 6.2 3 1.1 – 1.19 5.7