Clinical prone Evidence Description of sleeping included Type of studies: 28 Outcome: source: systematic Reduction in Systematic reviews, RCTs, or incidence of review observational SIDS studies met the Interventions: inclusion criteria. Evidence National statement campaigns to Quality of E: There is good reduce the risk included evidence to of SIDS studies: GRADE suggest that this evaluation of the intervention has Relevant quality of a sound Outcomes: evidence for theoretical basis Reductions in interventions. or that work in the incidence of this area is likely SIDS Synthesis: to have an Narrative impact but this Study has not been Population: demonstrated in Infants under 1 Findings: Two trials (this would year narrative apply to systematic interventions for Searches reviews of which RCTs were retrospective would be conducted case control particularly between: studies, which difficult or 1966 and April identified 19 unethical) 2007 studies, have found an Intervention: association National Included study types: between SIDS campaigns Observational and prone giving advice to studies sleeping position. tobacco One more recent smoke exposure systematic review, including Outcome: all 19 studies Reduction in the from the previous incidence of reviews plus 12 SIDS additional studies, reported Evidence that prone statement sleeping position Grade E: There
Clinical Evidence Type of source: Systematic review Interventions: National campaigns to reduce the risk of SIDS Relevant Outcomes: Reductions in the incidence of SIDS Study Population: Infants under 1 year Searches were conducted between: 1966 and April 2007 Included study types: Observational studies Description of included studies: 28 systematic reviews, RCTs, or observational studies met the inclusion criteria. Quality of included studies: GRADE evaluation of the quality of evidence for interventions. Synthesis: Narrative Findings: Two narrative systematic reviews of retrospective case control studies, which identified 19 studies, have found an association between SIDS and prone sleeping position. One more recent systematic review, including all 19 studies from the previous reviews plus 12 additional studies, reported that prone sleeping position prone sleeping Outcome: Reduction in incidence of SIDS Evidence statement E: There is good evidence to suggest that this intervention has a sound theoretical basis or that work in this area is likely to have an impact but this has not been demonstrated in trials (this would apply to interventions for which RCTs would be particularly difficult or unethical) Intervention: National campaigns giving advice to tobacco smoke exposure Outcome: Reduction in the incidence of SIDS Evidence statement Grade E: There