When is CRP increases rapidly? after infection, surgery, or trauma Within 48 hours after infection, the levels of Levels can rise to 1000 fold CRP can increase with how much? How will the levels decline? The levels decline rapidly when the stimulus stops Elevated CRP levels are found in bacterial infections, rheumatic viral infections, malignant diseases, tuberculosis, and after a heart attack CRP acts like an antibody and is capable of optimization, agglutination, precipitation, and activation of complement CRP binds to specific receptors on monocytes, macrophages and neutrophils, promotes phagocytosis Because the levels of CRP rise and then decline acute inflammation so rapidly, it is the most widely used indicator of CRP is a nonspecific indicator of disease or follow a disease process and observe the trauma, but it can be used to response to treatment of inflammation and infection CRP is also used to monitor what? malignancy and transplantation rejection How can CRP used to monitor malignancy and A rise in its level may mean a return of transplantation rejection? malignancy, or beginning of organ rejection An increased level of CRP is also a significant myocardial infarction and ischemic stroke in risk factor for people who have no previous history of cardiovascular disease Another major protein whose concentration can Serum amyloid A rise 1000 fold is Where can Serum amyloid A found? It is made in the liver and circulates in the plasma What is the role of Serum amyloid A? it is associated with HDL cholesterol, and is thought to play a role in metabolism of cholesterol By removing cholesterol from macrophages at cleaning up of the area the site tissue injury, amyloid A contributes to the Serum amyloid A levels increases in what types more in bacterial infection than in viral of infections? infections A series of serum proteins that are normally Complement present and whose function is mediation of inflammation refers to How many complement proteins are there? 9 Complements are activated by antibodies When are the complement proteins activated by in an event called classical complement cascade antibodies? Several additional proteins are involved in the alternate pathway The alternate pathway is triggered by microorganisms The major functions of complement are opsinization, chemotaxis, and of cells
When is CRP increases rapidly? after infection, surgery, or trauma Within 48 hours after infection, the levels of CRP can increase with how much? Levels can rise to 1000 fold How will the levels decline? The levels decline rapidly when the stimulus stops Elevated CRP levels are found in bacterial infections, rheumatic viral infections, malignant diseases, tuberculosis, and after a heart attack CRP acts like an antibody and is capable of optimization, agglutination, precipitation, and activation of complement CRP binds to specific receptors on monocytes, macrophages and neutrophils, promotes phagocytosis Because the levels of CRP rise and then decline so rapidly, it is the most widely used indicator of acute inflammation CRP is a nonspecific indicator of disease or trauma, but it can be used to follow a disease process and observe the response to treatment of inflammation and infection CRP is also used to monitor what? malignancy and transplantation rejection How can CRP used to monitor malignancy and transplantation rejection? A rise in its level may mean a return of malignancy, or beginning of organ rejection An increased level of CRP is also a significant risk factor for myocardial infarction and ischemic stroke in people who have no previous history of cardiovascular disease Another major protein whose concentration can rise 1000 fold is Serum amyloid A Where can Serum amyloid A found? It is made in the liver and circulates in the plasma What is the role of Serum amyloid A? it is associated with HDL cholesterol, and is thought to play a role in metabolism of cholesterol By removing cholesterol from macrophages at the site tissue injury, amyloid A contributes to the cleaning up of the area Serum amyloid A levels increases in what types of infections? more in bacterial infection than in viral infections A series of serum proteins that are normally present and whose function is mediation of inflammation refers to Complement How many complement proteins are there? 9 Complements are activated by antibodies When are the complement proteins activated by antibodies? in an event called classical complement cascade Several additional proteins are involved in the alternate pathway The alternate pathway is triggered by microorganisms The major functions of complement are opsinization, chemotaxis, and of cells