Pharmacotherapy Anxious symptoms – Nguyen RCT with French 100% Intervention: Intervention: 150 Hamilton N = 191 et al. 1 week outpatients adjustment Etifoxine mg/day for 28 days Anxiety (2006) follow-up seeing GPs disorder with Control: 2 mg/day Rating Scale after anxiety anxiolytic) for 28 days (HAM-A) Intervention: Control: Clinical Age: 44.0 Lorazepam Global (13.4) Stressor: 41% (benzodiazepine) Impression Male: 38% family-related; Scale (CGI) 30% work Sheehan Control: related; 9% Disability Age: 42.0 health; 20% Scale (SDS) (13.1) other Social Male: 30% Adjustment Scale
Pharmacotherapy – Anxious symptoms Nguyen et al. (2006) RCT with 1 week follow-up after French outpatients seeing GPs Intervention: Age: 44.0 (13.4) Male: 38% Control: Age: 42.0 (13.1) Male: 30% 100% adjustment disorder with anxiety Stressor: 41% family-related; 30% work related; 9% health; 20% other Intervention: Etifoxine anxiolytic) Control: Lorazepam (benzodiazepine) Intervention: 150 mg/day for 28 days Control: 2 mg/day for 28 days Hamilton Anxiety Rating Scale (HAM-A) Clinical Global Impression Scale (CGI) Sheehan Disability Scale (SDS) Social Adjustment Scale N = 191