Record concomitant medications. Perform a complete physical examination. Perform and record vital signs. Perform and record oximetry. Perform and record results of blood pressure testing. Collect blood for clinical laboratory tests (chemistry, hematology, prothrombin time, pregnancy test, methemoglobin, and serum nitrate). Perform and record spirometry. Collect sputum for culture. Obtain an echocardiogram. Obtain a chest x-ray. Schedule subject for Visit 2 in XX days. List all additional procedures, such as Randomize subject, Dispense study drug, Initiate subject diary, etc. Visit 2 (Day/Week/Month # include visit window) Record any Adverse Experiences and/or Review subject diary for adverse experiences and dosing compliance. Concomitant medications review. Perform abbreviated physical examination. Perform and record vital signs. Perform and record oximetry. Perform and record spirometry. List all additional procedures. Visit 3 (Day/Week/Month # include visit window) Record any Adverse Experiences and/or Review subject diary for adverse experiences and dosing compliance. Record changes to concomitant medications. Perform abbreviated physical examination. Perform and record vital signs.
Record concomitant medications. Perform a complete physical examination. Perform and record vital signs. Perform and record oximetry. Perform and record results of blood pressure testing. Collect blood for clinical laboratory tests (chemistry, hematology, prothrombin time, pregnancy test, methemoglobin, and serum nitrate). Perform and record spirometry. Collect sputum for culture. Obtain an echocardiogram. Obtain a chest x-ray. Schedule subject for Visit 2 in XX days. List all additional procedures, such as Randomize subject, Dispense study drug, Initiate subject diary, etc. Visit 2 (Day/Week/Month # include visit window) Record any Adverse Experiences and/or Review subject diary for adverse experiences and dosing compliance. Concomitant medications review. Perform abbreviated physical examination. Perform and record vital signs. Perform and record oximetry. Perform and record spirometry. List all additional procedures. Visit 3 (Day/Week/Month # include visit window) Record any Adverse Experiences and/or Review subject diary for adverse experiences and dosing compliance. Record changes to concomitant medications. Perform abbreviated physical examination. Perform and record vital signs.