Parameter/biomarker Obese controls Obese Lean controls P value Body weight (g) 35.9a 41.1a,b 30.9c 0.002 (32.7-44.3) (35.7-47.6) (29.2-33.6) (n=10) (n=12) (n=10) BMIs 4.4a 4.5a,b 3.3c <0.001 (4.1-4.8) (4.0-4.9) (3.1-3.5) (n=10) (n=12) (n=10) Weight cecum 191a 314a,b 128a,c 0.003 contents (mg) (104-234) (198-439) (93-152) Relative thickness of 0.64 (0.6-0.7) 0.73 (0.7-0.8) 0.72 (0.6-0.7) 0.08 outer colon wall Different letters state statistical significance difference. mRNA levels of biomarkers involved in inflammation, cellular Supplementary Table S5. stress, and gut barrier function in colonic mucosal cells.
Parameter/biomarker Obese controls Obese Lean controls P value Body weight (g) 35.9a (32.7-44.3) (n=10) 41.1a,b (35.7-47.6) (n=12) 30.9c (29.2-33.6) (n=10) 0.002 BMIs 4.4a (4.1-4.8) (n=10) 4.5a,b (4.0-4.9) (n=12) 3.3c (3.1-3.5) (n=10) <0.001 Weight cecum contents (mg) 191a (104-234) 314a,b (198-439) 128a,c (93-152) 0.003 Relative thickness of outer colon wall 0.64 (0.6-0.7) 0.73 (0.7-0.8) 0.72 (0.6-0.7) 0.08 Different letters state statistical significance difference. Supplementary Table S5. mRNA levels of biomarkers involved in inflammation, cellular stress, and gut barrier function in colonic mucosal cells.