= seizure threshold aminophylline ↓ Not a MH trigger Produces anesthesia” Does not trigger MH “dissociative Dissociation between Antiemetic at low doses- 10 15 mg Thalamocortical + limbic system Increased incidence of PONV – Cataleptic state = eyes open with Antipruritic with neuraxial opioids (10 slow nystagmic gaze mg) Does not produce analgesia Amnestic and analgesic Anticonvulsant - duration in Pain on injection Does not trigger MH ↓seizure pt’s undergoing ECT No histamine release Oculocardiac Reflex in pedi strabismus Can use with acute hypovolemia ↑ surgery Do not use with critically ill pt. b/c of ↓ Five and Dime response = catecholamine stores asystole Misc. Vagal stimulation Inhibits platelet aggregation Inc. potential of this w/propofol Analgesia subanesthetic doses –at Aquavan H2O soluble prodrug that Good for somatic pain – becomes propofol in the body Inhibits spinal NMDA receptors Does not same anesthetic Analgesia during labor w/o effect, pain on injection, neonate depression infection, hypertriglyceridemia Not for first option intervention as propofol Has a large Vd and higher Varying degree of hypertonus and potency than propofol purposeful skeletal muscle movement independent of surgical stimulation Prolonged infusion can have green urine (r/t phenols) or cloudy urine (r/t uric acid crystals) both not harmful –
aminophylline = ↓ seizure threshold Misc. Not a MH trigger Antiemetic at low doses- 10 – 15 mg Antipruritic with neuraxial opioids (10 mg) Anticonvulsant - ↓seizure duration in pt’s undergoing ECT ↑ Oculocardiac Reflex in pedi strabismus surgery Five and Dime response = asystole Vagal stimulation Inc. potential of this w/propofol Aquavan – H2O soluble prodrug that becomes propofol in the body Does not same anesthetic effect, pain on injection, infection, hypertriglyceridemia as propofol Has a large Vd and higher potency than propofol Prolonged infusion can have green urine (r/t phenols) or cloudy urine (r/t uric acid crystals) – both not harmful Produces “dissociative anesthesia” Dissociation between Thalamocortical + limbic system Cataleptic state = eyes open with slow nystagmic gaze Amnestic and analgesic Does not trigger MH No histamine release Can use with acute hypovolemia Do not use with critically ill pt. b/c of ↓ catecholamine stores Inhibits platelet aggregation Analgesia –at subanesthetic doses Good for somatic pain Inhibits spinal NMDA receptors Analgesia during labor w/o neonate depression Not for first option intervention Varying degree of hypertonus and purposeful skeletal muscle movement independent of surgical stimulation Does not trigger MH Increased incidence of PONV Does not produce analgesia Pain on injection