progressive symptoms In 19/648 evaluated segments, curve fitting was not possible N=102 segments because of artefacts or noise: Interobserver variability: r = 0.96 intraobserver variability: r = 0.99 Cury et al. () Level III-1 N=32/33 patients SP-CMR Per artery NR 19 9 8 60 Poor-quality CMR images: 1/33 suspected of having CAD patients Brazil Low risk of SP-CMR + LGE ICA ≥70% DS 20 6 7 63 bias N=96 coronary territories Groothuis et Level III-1 N=88/192 patients with SP-CMR + LGE FFR ≤ 0.75 30% 22 11 4 51 8/210 patients had no or low or intermediate PTP incomplete CMR al. () Some risk of of having CAD unknown prior claustrophobia: The bias 3/210 Netherlands Intraobserver agreement for CMR: kappa = 0.78 + 0.09 Interobserver agreement for CMR: kappa = 0.81 + 0.09 Heitner et al. Level III-1 N=60/68 patients with SP-CMR ICA ≥50% DS 13% 7 5 1 47 Withdrew consent before () acute chest discomfort + clinical imaging: 5/68 High risk of LGE viability 3 9 5 43 and an intermediate PTP follow-up USA bias Could not undergo CMR due to: of CAD SP-CMR + LGE 8 4 0 48 large body circumference: 2/68 claustrophobia: 1/68 Merkle et al. Level III-2 N=73 patients with SP-CMR ICA ≥50% DS 27% 16 8 4 45 - () suspected CAD Low risk of n=32 women 5 1 1 25 Germany bias n=41 men 11 7 3 20 Cheng et al. Level III-2 N=61/65 patients with SP-CMR ICA ≥50% DS 66% 39 5 1 16 No CMR results due to: () suspected CAD Claustrophobia: 2/65 patients Low risk of Adenosine intolerance: 1/65 UK bias ICA was cancelled for 1/65
progressive symptoms N=102 segments In 19/648 evaluated segments, curve fitting was not possible because of artefacts or noise: Interobserver variability: r = 0.96 intraobserver variability: r = 0.99 Cury et al. () Brazil Level III-1 Low risk of bias N=32/33 patients suspected of having CAD N=96 coronary territories SP-CMR SP-CMR + LGE Per artery ICA ≥70% DS NR 19 20 9 6 8 7 60 63 Poor-quality CMR images: 1/33 patients Groothuis et al. () The Netherlands Level III-1 Some risk of bias N=88/192 patients with low or intermediate PTP of having CAD SP-CMR + LGE FFR ≤ 0.75 30% 22 11 4 51 8/210 patients had no or incomplete CMR unknown prior claustrophobia: 3/210 Intraobserver agreement for CMR: kappa = 0.78 + 0.09 Interobserver agreement for CMR: kappa = 0.81 + 0.09 Heitner et al. () USA Level III-1 High risk of bias N=60/68 patients with acute chest discomfort and an intermediate PTP of CAD SP-CMR LGE viability SP-CMR + LGE ICA ≥50% DS + clinical follow-up 13% 7 3 8 5 9 4 1 5 0 47 43 48 Withdrew consent before imaging: 5/68 Could not undergo CMR due to: large body circumference: 2/68 claustrophobia: 1/68 Merkle et al. () Germany Level III-2 Low risk of bias N=73 patients with suspected CAD SP-CMR n=32 women n=41 men ICA ≥50% DS 27% 16 5 11 8 1 7 4 1 3 45 25 20 - Cheng et al. () UK Level III-2 Low risk of bias N=61/65 patients with suspected CAD SP-CMR ICA ≥50% DS 66% 39 5 1 16 No CMR results due to: Claustrophobia: 2/65 patients Adenosine intolerance: 1/65 ICA was cancelled for 1/65