concentration of cosolute. The buffering capacity of the protein itself will be used to control the pH. If this hypothesis proves to be correct, there is great potential for using cosolute mixtures of functional groups at bespoke ratios for desired characteristics in formulations. This thesis also aims to prove or disprove the occurrence of arginine self-association in solution through experimental data obtained from Nanoparticle Tracking Analysis (NTA), and to explore the mechanisms by which this clustering might occur.
concentration of cosolute. The buffering capacity of the protein itself will be used to control the pH. If this hypothesis proves to be correct, there is great potential for using cosolute mixtures of functional groups at bespoke ratios for desired characteristics in formulations. This thesis also aims to prove or disprove the occurrence of arginine self-association in solution through experimental data obtained from Nanoparticle Tracking Analysis (NTA), and to explore the mechanisms by which this clustering might occur.