E.coli O157:H7 causes Haemolytic Uremic Syndrome Salmonella enteritidis C. difficile diagnosed through detection of a cytopathic toxin in the stool. – General management for diarrhoea Ciprofloxacin (Quinolone) Severe bacterial – Doxycycline (Tetracycline) Broad spectrum – Amoxicillin (Beta lactam) spectrum, GI SE – Codeine Chronic and persistent – Tropical Disease / fever in returned traveller Entamboeba Histolytica (Amoebiasis) - faecal/ oral, intermittent fever, swelling in hypochondrium - liver abcess, Trophozoites remain in bowel or invade extra intestinal tissues, leaving GI ulcers severe amoebic dysentery “flask-shaped” – Intestinal Amoebiasis (Amoebic dysentery) Get tissue ulceration and necrosis. The presentation varies from mild bloody diarrhoea to fulminating colitis, with risk of dilatation, perforation and peritonitis Can get and mucus in the stool Increased incidence in tropical countries Amoebic Liver abscess If enters portal vein and then the liver. Get an abscess (usually single) with tender hepatomegaly, high swinging and profound malaise. Amoebic fluorescent antibody test (FAT) is positive in 90% of patients with abscess and 70% with active colitis Salmonella typhi (Typhoid eneteric fever) Think when has headache and GI symptoms – – Faecal/ oral spread, high fever, malaise and diarrhoea, CNS and delirium; Gram bacilli –ve Humans are the only known reservoir and spread is faecal-oral Incubation period of 10-14 days Insidious onset of headache, dry cough and constipation Rising and relative bradycardia
E.coli O157:H7 causes Haemolytic Uremic Syndrome Salmonella enteritidis C. difficile – diagnosed through detection of a cytopathic toxin in the stool. General management for diarrhoea Ciprofloxacin (Quinolone) – Severe bacterial Doxycycline (Tetracycline) – Broad spectrum Amoxicillin (Beta lactam) – spectrum, GI SE Codeine – Chronic and persistent Tropical Disease / fever in returned traveller Entamboeba Histolytica (Amoebiasis) - faecal/ oral, intermittent fever, swelling in hypochondrium - liver abcess, Trophozoites remain in bowel or invade extra intestinal tissues, leaving “flask-shaped” GI ulcers – severe amoebic dysentery Intestinal Amoebiasis (Amoebic dysentery) Get tissue ulceration and necrosis. The presentation varies from mild bloody diarrhoea to fulminating colitis, with risk of dilatation, perforation and peritonitis Can get and mucus in the stool Increased incidence in tropical countries Amoebic Liver abscess If enters portal vein and then the liver. Get an abscess (usually single) with tender hepatomegaly, high swinging and profound malaise. Amoebic fluorescent antibody test (FAT) is positive in 90% of patients with abscess and 70% with active colitis Salmonella typhi (Typhoid – eneteric fever) – Think when has headache and GI symptoms Faecal/ oral spread, high fever, malaise and diarrhoea, CNS and delirium; Gram –ve bacilli Humans are the only known reservoir and spread is faecal-oral Incubation period of 10-14 days Insidious onset of headache, dry cough and constipation Rising and relative bradycardia