Cognitive behavioural therapy for insomnia with an adjunctive psychological intervention Study 1 Study 2 Study 3 4 Study 5 Authors & year Germain et al., 2012 Harb et al., 2009 Margolies et al., Swanson et al., 2009 Ulmer et al., 2011 Design RCT with four Single group RCT Single pre-post RCT month follow-up Intervention (I) I1: Behavioural I: Cognitive I: Cognitive I: Cognitive behavioural I: Cognitive behavioural and sleep intervention behavioural therapy behavioural therapy therapy with adjunctive therapy for insomnia and Comparison (C) incorporating for insomnia for insomnia with exposure, relaxation and imagery rehearsal therapy cognitive combined with adjunctive imagery rescripting therapy C: Usual care behavioural therapy imagery rehearsal rehearsal therapy for insomnia and (when participants imagery rehearsal reported problem therapy nightmares) I2: C: Waitlist Pharmacotherapy C2: Placebo Population US veterans with US OIF veterans US OEF/OIF veterans US veterans (90% US veterans with insomnia Mean age (SD) sleep complaints recently post with PTSD and Vietnam) with PTSD and and PTSD Gender (%) Mean age: 40.9 deployment with insomnia insomnia Mean age: 46 (11.1) (13.2) PTSD and recurrent Mean age: 37.7 (9.1) Mean age: 59 (4.0) Gender: Male (68%) Gender: Male (90%) nightmares Gender: Male (90%) Gender: Male (100%) Mean age: 37.3 (9.2) Gender: Male (100%) Delivered to Individual Individual Individual Group Individual Five to eight Six sessions Four sessions, 60 Ten sessions, 90 minutes Six sessions, 60 minutes Dosage (total number of sessions, 45 CBT; three IRT) minutes each each each sessions) minutes each Primary - Insomnia (Sleep - Insomnia (PSQI; - Insomnia (Sleep - Insomnia (Sleep diary: - Insomnia (Sleep diary: total Outcome diary: total sleep sleep diary) diary: total wake time; total sleep time; sleep sleep time; sleep onset
Cognitive behavioural therapy for insomnia with an adjunctive psychological intervention Study 1 Study 2 Study 3 4 Study 5 Authors & year Germain et al., 2012 Harb et al., 2009 Margolies et al., Swanson et al., 2009 Ulmer et al., 2011 Design RCT with four month follow-up Single group RCT Single pre-post RCT Intervention (I) and Comparison (C) I1: Behavioural sleep intervention incorporating cognitive behavioural therapy for insomnia and imagery rehearsal therapy I2: Pharmacotherapy C2: Placebo I: Cognitive behavioural therapy for insomnia combined with imagery rehearsal I: Cognitive behavioural therapy for insomnia with adjunctive imagery rehearsal therapy (when participants reported problem nightmares) C: Waitlist I: Cognitive behavioural therapy with adjunctive exposure, relaxation and rescripting therapy I: Cognitive behavioural therapy for insomnia and imagery rehearsal therapy C: Usual care Population Mean age (SD) Gender (%) US veterans with sleep complaints Mean age: 40.9 (13.2) Gender: Male (90%) US OIF veterans recently post deployment with PTSD and recurrent nightmares Mean age: 37.3 (9.2) Gender: Male (100%) US OEF/OIF veterans with PTSD and insomnia Mean age: 37.7 (9.1) Gender: Male (90%) US veterans (90% Vietnam) with PTSD and insomnia Mean age: 59 (4.0) Gender: Male (100%) US veterans with insomnia and PTSD Mean age: 46 (11.1) Gender: Male (68%) Delivered to Individual Individual Individual Group Individual Dosage (total number of sessions) Five to eight sessions, 45 minutes each Six sessions CBT; three IRT) Four sessions, 60 minutes each Ten sessions, 90 minutes each Six sessions, 60 minutes each Primary Outcome - Insomnia (Sleep diary: total sleep - Insomnia (PSQI; sleep diary) - Insomnia (Sleep diary: total wake time; - Insomnia (Sleep diary: total sleep time; sleep - Insomnia (Sleep diary: total sleep time; sleep onset