regular health DBP: 0.5mmHg no advice hours (SEM: 4.91, related to sodium 95%CI: -9.12, Control group: restriction 10.12) At 12 months: 159.5mmol/24 hours (based on available urinary data for 11 out of 16 participants), mean change from baseline: +26.35mmol/day Key features for bias assessment of randomised trials Citation Method of Allocation Blinding Loss to Use of Ceasing study Reporting all Funding randomisation concealment early for benefit outcome source where results required Silman et Unclear (no Unclear (no Participants: <10%, low risk Unclear, used No (Low risk) Yes (Low risk) Unclear, al (1983) description of description of not blinded as weighted mean assume method of method of given advice average of hospital sequence concealment of but blinded to available data funding generation) allocation) purpose of urinary sodium
regular health no advice related to sodium restriction hours Control group: At 12 months: 159.5mmol/24 hours (based on available urinary data for 11 out of 16 participants), mean change from baseline: +26.35mmol/day DBP: 0.5mmHg (SEM: 4.91, 95%CI: -9.12, 10.12) Key features for bias assessment of randomised trials Citation Method of randomisation Allocation concealment Blinding Loss to Use of where required Ceasing study early for benefit Reporting all outcome results Funding source Silman et al (1983) Unclear (no description of method of sequence generation) Unclear (no description of method of concealment of allocation) Participants: not blinded as given advice but blinded to purpose of urinary sodium <10%, low risk Unclear, used weighted mean average of available data No (Low risk) Yes (Low risk) Unclear, assume hospital funding