FTS, CVS, amniocentesis – see above Resources provided in association with comparator – confirmatory testing for women testing positive for common trisomies FTS, CVS, amniocentesis – see above Resources used to manage women with identified fetal trisomy Hospital admission Hospital Hospital To be estimated in To be for elective SBA based on positive verified in termination result rate with NIPT, SBA. Cost has invasive testing been uptake, and PPV of estimated at NIPT $1,106 (Harris 2004) Resources used to manage unidentified fetal trisomy Management of Health care Health care All women giving birth To be Down syndrome system system to infants with T21 verified in SBA. Mean annual cost has been estimated at $4,209 (Geelhoed et al 2011) [Year 1 cost if one year horizon is chosen] Management of trisomies 18 and 13
FTS, CVS, amniocentesis – see above Resources provided in association with comparator – confirmatory testing for women testing positive for common trisomies FTS, CVS, amniocentesis – see above Resources used to manage women with identified fetal trisomy Hospital admission for elective termination Hospital Hospital To be estimated in SBA based on positive result rate with NIPT, invasive testing uptake, and PPV of NIPT To be verified in SBA. Cost has been estimated at $1,106 (Harris 2004) Resources used to manage unidentified fetal trisomy Management of Down syndrome Health care system Health care system All women giving birth to infants with T21 To be verified in SBA. Mean annual cost has been estimated at $4,209 (Geelhoed et al 2011) [Year 1 cost if one year horizon is chosen] Management of trisomies 18 and 13