skin irritation rabbit severe irritant (Burnette, (F) 1980) corrosive skin corrosion rabbit (Nitka, 1983) (F) eye irritation rabbit severe irritant (Burnette, (F) 1980) skin sensitisation humans non-sensitiser (Shelanski, (E) 1959) 9.1.1 Oral Toxicity (Kresimir, 1998) rat/CD [Crl:CD(SD)BR] Species/strain: 5/sex for test Number/sex of animals: 2 000 mg/kg, notified chemical Dose 14 days Observation period: 1.96 mL/kg of test substance administered orally by gavage Method of administration: OECD Guideline TG 401 Test method: no of systemic toxicity Clinical observations: nil Mortality: none Morphological findings: > 2 000 mg/kg LD50: the notified chemical was of very low oral toxicity in Result: rats 9.1.2 Dermal Toxicity No data were submitted for acute dermal toxicity. The notifier states on the basis of very low acute oral toxicity, the expected low dermal absorption based on relatively high molecular weight (> 500) and low water-octanol partition coefficient (log Pow = -1), it is unlikely to be toxic via the dermal route. 9.1.3 Inhalation Toxicity No data were submitted for inhalation toxicity. The notifier states on the of very low acute oral toxicity and the expected low vapour pressure it is unlikely to be toxic via the inhalation route.
skin irritation (F) skin corrosion (F) rabbit rabbit severe irritant corrosive (Burnette, 1980) (Nitka, 1983) eye irritation (F) rabbit severe irritant (Burnette, 1980) skin sensitisation (E) humans non-sensitiser (Shelanski, 1959) 9.1.1 Oral Toxicity (Kresimir, 1998) Species/strain: rat/CD [Crl:CD(SD)BR] Number/sex of animals: 5/sex for test Dose 2 000 mg/kg, notified chemical Observation period: 14 days Method of administration: 1.96 mL/kg of test substance administered orally by gavage Test method: OECD Guideline TG 401 Clinical observations: no of systemic toxicity Mortality: nil Morphological findings: none LD50: > 2 000 mg/kg Result: the notified chemical was of very low oral toxicity in rats 9.1.2 Dermal Toxicity No data were submitted for acute dermal toxicity. The notifier states on the basis of very low acute oral toxicity, the expected low dermal absorption based on relatively high molecular weight (> 500) and low water-octanol partition coefficient (log Pow = -1), it is unlikely to be toxic via the dermal route. 9.1.3 Inhalation Toxicity No data were submitted for inhalation toxicity. The notifier states on the of very low acute oral toxicity and the expected low vapour pressure it is unlikely to be toxic via the inhalation route.