Evidence Profile COGNITIVE THERAPIES Study 1 Study 2 Author’s & Year Mohr, C.; Ho, Duffecy, Reifler, Sokol, Serfaty, Haworth, Blanchard, Burns, Jin & Siddique, 2012 Buszewicz, Murad & King, 2009 RCT RCT Design Intervention (I) and (I): Telephone-administered cognitive (I): Cognitive behavioural Comparison (C) behavioural therapy (T-CBT) therapy (CBT) + TAU (GP contact) (C): Face-to-face cognitive behavioural therapy (CBT) (C): Talking control group + TAU (GP contact) (C): TAU (GP contact) Country USA UK 18 weekly sessions. T-CBT patients Up to 12 (average of 50 attended significantly more sessions (mean minute sessions 16) than those receiving CBT (mean 14) (Individual) Intervention Delivery (Individual) methods, frequency, duration, (delivered to) Met criteria for MDD and scored on Geriatric Mental State Diagnosis ≥16 Depression Diagnosis Ham-D of Depression Primary Outcome Discontinuation vs. non-discontinuation of Depression symptoms ( BDI-II) domain (Measure(s)) treatment before week 18 Secondary Outcome Depression symptoms (HRSD; PHQ-9) Anxiety (BAI) domain (Measure(s)) Social functioning (SFQ) Quality of life (Euroqol) Characteristics of N = 325 N = 204 Sample Aged ≥65 Participants: I N = 163 N = 70 age (M=48, SD=14) age (M=74, SD=8) 77% female 84% female Participants: C N = 162 N = 67 age (M= 48, SD=13) (Talking control + TAU) 78% female
Evidence Profile COGNITIVE THERAPIES Study 1 Study 2 Author’s & Year Mohr, C.; Ho, Duffecy, Reifler, Sokol, Burns, Jin & Siddique, 2012 Serfaty, Haworth, Blanchard, Buszewicz, Murad & King, 2009 Design RCT RCT Intervention (I) and Comparison (C) (I): Telephone-administered cognitive behavioural therapy (T-CBT) (C): Face-to-face cognitive behavioural therapy (CBT) (I): Cognitive behavioural therapy (CBT) + TAU (GP contact) (C): Talking control group + TAU (GP contact) (C): TAU (GP contact) Country USA UK Intervention Delivery methods, frequency, duration, (delivered to) 18 weekly sessions. T-CBT patients attended significantly more sessions (mean 16) than those receiving CBT (mean 14) (Individual) Up to 12 (average of 50 minute sessions (Individual) Depression Diagnosis Met criteria for MDD and scored ≥16 on Ham-D Geriatric Mental State Diagnosis of Depression Primary Outcome domain (Measure(s)) Discontinuation vs. non-discontinuation of treatment before week 18 Depression symptoms ( BDI-II) Secondary Outcome domain (Measure(s)) Depression symptoms (HRSD; PHQ-9) Anxiety (BAI) Social functioning (SFQ) Quality of life (Euroqol) Characteristics of Sample N = 325 N = 204 Aged ≥65 Participants: I N = 163 age (M=48, SD=14) 77% female N = 70 age (M=74, SD=8) 84% female Participants: C N = 162 age (M= 48, SD=13) 78% female N = 67 (Talking control + TAU)