studies were maximal, respirable concentrations, which are well in excess of defined occupational exposure limits. Fertility effects : No known significant effects or critical hazards. Numerical measures of toxicity Acute toxicity estimates Inhalation (dusts and mists) 1.5 mg/I Other information : Not available Section 12. Ecological information Toxicity Product/ingredient name Test Endpoint Exposure Species Result 24 hours Diphenylmethane 4,4'- OECD 202 Acute EC50 Daphnia >1000 mg/I Static diisocyanate Daphnia sp. Acute Immobilization Test OECD 203 Fish, 96 hours Acute LC50 Fish >1000 mg/I Acute Toxicity Test Static OECD 211 Daphnia Chronic NOEC 21 days Daphnia >10 mg/I Semi-static Reproduction Test OECD 201 Alga, Chronic 72 hours Algae 1640 mg/I Growth Inhibition Static Test Homopolymer of OECD 201 Alga, Acute EC50 72 hours >1640 mg/I methylenediphenyl Growth Inhibition Static diisocyanate Test OECD 209 EC50 3 hours Bacteria >100 mg/I Activated Sludge, Static Respiration Inhibition Test OECD 202 Acute EC50 24 hours Daphnia >1000 mg/I Daphnia sp. Static Immobilization Test OECD 203 Fish, LC50 96 hours Fish >1000 mg/I Acute Toxicity Test Static OECD 211 Daphnia Chronic NOEC 21 days Daphnia >10 mg/I Magna Semi-static Reproduction Test 2,6-di-tert-butyl-p-cresol EU EC C.3 Algal Acute EC50 72 Algae >0.4 mg/I Inhibition Test Static EU EC 88/302/EC Acute EC50 3 hours Bacteria >10000 mg/I Static OECD 202 Daphnia EC50 48 Daphnia 0.61 mg/I sp. Acute Static Immobilization Test EU EC 88/302/EC Chronic ECO 3 hours Bacteria 1000 mg/I Static EU EC C.2 Acute Chronic ECO 48 hours Daphnia >0.31 mg/I 8/5/2014. Not available. 14/20
studies were maximal, respirable concentrations, which are well in excess of defined occupational exposure limits. Fertility effects : No known significant effects or critical hazards. Numerical measures of toxicity Acute toxicity estimates Inhalation (dusts and mists) Other information : Not available 1.5 mg/I Section 12. Ecological information Toxicity Product/ingredient name Test Endpoint Exposure Species Result Diphenylmethane 4,4'- diisocyanate OECD 202 Daphnia sp. Acute Acute EC50 24 hours Static Daphnia >1000 mg/I Immobilization Test OECD 203 Fish, Acute Toxicity Test Acute LC50 96 hours Static Fish >1000 mg/I OECD 211 Daphnia Chronic NOEC 21 days Daphnia >10 mg/I Semi-static Reproduction Test OECD 201 Alga, Growth Inhibition Chronic 72 hours Static Algae 1640 mg/I Test Homopolymer of methylenediphenyl diisocyanate OECD 201 Alga, Growth Inhibition Test Acute EC50 72 hours Static >1640 mg/I OECD 209 EC50 3 hours Bacteria >100 mg/I Activated Sludge, Respiration Static Inhibition Test OECD 202 Daphnia sp. Acute EC50 24 hours Static Daphnia >1000 mg/I Immobilization Test OECD 203 Fish, Acute Toxicity Test LC50 96 hours Static Fish >1000 mg/I OECD 211 Daphnia Chronic NOEC 21 days Daphnia >10 mg/I Magna Semi-static Reproduction Test 2,6-di-tert-butyl-p-cresol EU EC C.3 Algal Acute EC50 72 Algae >0.4 mg/I Inhibition Test Static EU EC 88/302/EC Acute EC50 3 hours Bacteria >10000 mg/I Static OECD 202 Daphnia sp. Acute EC50 48 Static Daphnia 0.61 mg/I Immobilization Test EU EC 88/302/EC Chronic ECO 3 hours Bacteria 1000 mg/I Static EU EC C.2 Acute Chronic ECO 48 hours Daphnia >0.31 mg/I 8/5/2014. Not available. 14/20