Parallel To test the 34 overweight All subjects Compliance by Participants Significant Increased water Robitaille 2005 plasma premenopausal women consumed an returned uneaten were increase in intake in oat lipoprotein/ lipid (18-53y). Cholesterol NCEP step 1 diet. muffins. Dietary at significant group. No response to an status was not The treatment intake by 3d food baseline. Oat, decrease in total adverse effects. oat bran-rich specified. consumed 2 records. Blood but not control, cholesterol/HDL-C supplement in muffins enriched lipids measured group prepared ratio. overweight in oat-bran per enzymatically, muffins. day (28g/day of LDL-C calculated. changes in total women. oat bran; 2.31 g ANOVA and t-test cholesterol, analysis. and TG. 2wk run-in then 4wk test period. Rondanelli To compare the 24 mildly Diet provided as Compliance Minimised by Significant Intervention was effects of hypercholesterolaemic 7d rotating menu. assessed at cross-over decrease in total well tolerated. 2011 (from men (18-60y). During barley weekly visits, design and cholesterol and barley bran) with period subjects unclear method. provision of LDL-C. the effect of rice consumed 5.99g Dietary intake by whole diet. bran on extracted -glucan 3d food record increase in concentration in in pasta, rice to study and mildly cakes, soup and calculated from sauce. In rice provided foods men. period subjects during study. ate rice bran Blood lipids enriched foods. measured 3wk run-in, 2x 4wk enzymatically, intervention with LDL-C measured 3wk washout. directly. Statistical analysis by t-test and multilevel mixed-effects linear regression.
Robitaille 2005 Parallel To test the plasma lipoprotein/ lipid response to an oat bran-rich supplement in overweight women. 34 overweight premenopausal women (18-53y). Cholesterol status was not specified. All subjects consumed an NCEP step 1 diet. The treatment consumed 2 muffins enriched in oat-bran per day (28g/day of oat bran; 2.31 g 2wk run-in then 4wk test period. Compliance by returned uneaten muffins. Dietary intake by 3d food records. Blood lipids measured enzymatically, LDL-C calculated. ANOVA and t-test analysis. Participants were at baseline. Oat, but not control, group prepared muffins. Significant increase in significant decrease in total cholesterol/HDL-C ratio. changes in total cholesterol, and TG. Increased water intake in oat group. No adverse effects. Rondanelli 2011 To compare the effects of (from barley bran) with the effect of rice bran on concentration in mildly men. 24 mildly hypercholesterolaemic men (18-60y). Diet provided as 7d rotating menu. During barley period subjects consumed 5.99g extracted -glucan in pasta, rice cakes, soup and sauce. In rice period subjects ate rice bran enriched foods. 3wk run-in, 2x 4wk intervention with 3wk washout. Compliance assessed at weekly visits, unclear method. Dietary intake by 3d food record to study and calculated from provided foods during study. Blood lipids measured enzymatically, LDL-C measured directly. Statistical analysis by t-test and multilevel mixed-effects linear regression. Minimised by cross-over design and provision of whole diet. Significant decrease in total cholesterol and LDL-C. increase in Intervention was well tolerated.