Table 2. Data source and methods adopted by included studies Methods for valuing productivity losses a Study Disease specification Basis of analyses Prospective Epidemiological Estimating Carer lost Patient lost Patient lost Results of productivity productivity productivity or approach resource sensitivity retrospective consumption due to due to analysis morbidity mortality reported? Behan et al [] Schizophrenia (both DSM-IV and Multiple source including the Retrospective Prevalence Mixed Opportunity HCA WTP No ICD-10 were used in patients National Inpatient Reporting cost identification) System, survey, census, published literature etc. Desai et al [] Schizophrenic disorder (ICD-9, code Medical Expenditure Panel Survey. Retrospective Prevalence Bottom-up Opportunity HCA HCA Yes 295) or other non-organic cost psychoses (ICD-9, code 298) Ekman et al [] Schizophrenia (ICD-10, codes F20; Northern Stockholm Psychiatry, the Retrospective Prevalence Bottom-up × HCA × No F21; F23.1,2,8,9; F25.1,8,9) National Board of Health and Welfare, Swedish Social Insurance Agency, and published studies. Evensen et al [] Schizophrenia and schizoaffective Comprehensive and mandatory Retrospective Prevalence Top-down × HCA × No disorder (ICD-10, F20 and F25) health and welfare registers in Norway. Frey [] Schizophrenia (ICD-10-GM, F20.‘x’) Data from Sickness fund (Techniker Retrospective Prevalence Econometric Opportunity FCA FCA Yes Krankenkasse, a public health cost insurance provider) and Federal Statistical Office. Goeree et al [] Schizophrenia A review of the published Retrospective Prevalence Mixed × HCA FCA Yes literature, secondary analysis of administrative datasets, and information collected directly from various federal and provincial government programs and services. Goeree et al [] Schizophrenia Published literature and direct Retrospective Prevalence Mixed × HCA FCA Yes contact with representatives from various provincial and federal programs. Guest et al [] Schizophrenia A discrete event model which was Retrospective Incidence Bottom-up Opportunity HCA HCA Yes populated by literature review and cost interviews among a panel of healthcare professionals. Schizophrenia A Markov model which was Retrospective Incidence Bottom-up Opportunity HCA × Yes [] populated by data obtained from cost published literature and assumptions.
Table 2. Data source and methods adopted by included studies Methods for valuing productivity losses a Study Disease specification Basis of analyses Prospective or retrospective Epidemiological approach Estimating resource consumption Carer lost productivity Patient lost productivity due to morbidity Patient lost productivity due to mortality Results of sensitivity analysis reported? Behan et al [] Schizophrenia (both DSM-IV and ICD-10 were used in patients identification) Multiple source including the National Inpatient Reporting System, survey, census, published literature etc. Retrospective Prevalence Mixed Opportunity cost HCA WTP No Desai et al [] Schizophrenic disorder (ICD-9, code 295) or other non-organic psychoses (ICD-9, code 298) Medical Expenditure Panel Survey. Retrospective Prevalence Bottom-up Opportunity cost HCA HCA Yes Ekman et al [] Schizophrenia (ICD-10, codes F20; F21; F23.1,2,8,9; F25.1,8,9) Northern Stockholm Psychiatry, the National Board of Health and Welfare, Swedish Social Insurance Agency, and published studies. Retrospective Prevalence Bottom-up × HCA × No Evensen et al [] Schizophrenia and schizoaffective disorder (ICD-10, F20 and F25) Comprehensive and mandatory health and welfare registers in Norway. Retrospective Prevalence Top-down × HCA × No Frey [] Schizophrenia (ICD-10-GM, F20.‘x’) Data from Sickness fund (Techniker Krankenkasse, a public health insurance provider) and Federal Statistical Office. Retrospective Prevalence Econometric Opportunity cost FCA FCA Yes Goeree et al [] Schizophrenia A review of the published literature, secondary analysis of administrative datasets, and information collected directly from various federal and provincial government programs and services. Retrospective Prevalence Mixed × HCA FCA Yes Goeree et al [] Schizophrenia Published literature and direct contact with representatives from various provincial and federal programs. Retrospective Prevalence Mixed × HCA FCA Yes Guest et al [] Schizophrenia A discrete event model which was populated by literature review and interviews among a panel of healthcare professionals. Retrospective Incidence Bottom-up Opportunity cost HCA HCA Yes [] Schizophrenia A Markov model which was populated by data obtained from published literature and assumptions. Retrospective Incidence Bottom-up Opportunity cost HCA × Yes