Younes et al Retrospective CS Patients with primary malignant solid tumour, primary Intervention: surgical resection 1. Adverse events: not defined. (2009) controlled or controllable, nodules confined to lung Level IV 2. Overall survival rate: Kaplan-Meier test. N = 529 (median resected: 1) Risk of bias: High Comparator: NA 3. Prognostic factors: univariate and multivariate Largest diameter: ≤ 1 cm 163/526 (31%); 1.1–3cm analyses. NR 256/526 (48.7%); >3cm 107/526 (20.3%) M/F ratio: 267:262 Age 0–12 years: 38/529 (7.2%); 13–40 years: 155/529 (29.3%); 65 years: 231/529 (43.7%); 70 years: 105/529 (19.8%) Primary tumours: Adenocarcinoma 154/528 (29.2%), osteosarcoma 86/528 (16.3%), squamous cell 81/528 (15.3%), soft tissue sarcoma 75/528 (14.2%), melanoma 48/528 (9.2%), other: 84/528 (15.9%)
Younes et al (2009) Retrospective CS Level IV Risk of bias: High NR Patients with primary malignant solid tumour, primary controlled or controllable, nodules confined to lung N = 529 (median resected: 1) Largest diameter: ≤ 1 cm 163/526 (31%); 1.1–3cm 256/526 (48.7%); >3cm 107/526 (20.3%) M/F ratio: 267:262 Age 0–12 years: 38/529 (7.2%); 13–40 years: 155/529 (29.3%); 65 years: 231/529 (43.7%); 70 years: 105/529 (19.8%) Primary tumours: Adenocarcinoma 154/528 (29.2%), osteosarcoma 86/528 (16.3%), squamous cell 81/528 (15.3%), soft tissue sarcoma 75/528 (14.2%), melanoma 48/528 (9.2%), other: 84/528 (15.9%) Intervention: surgical resection Comparator: NA 1. Adverse events: not defined. 2. Overall survival rate: Kaplan-Meier test. 3. Prognostic factors: univariate and multivariate analyses.