Parallel To compare 21 males with Conducted in a Intake monitored Groups matched Significant Anderson 1991 effects of hypercholesterolaemia. metabolic ward in metabolic ward. for BMI. decrease in soluble (oat) and 20 completed study, 10 with food prepared Blood lipids Baseline and LDL-C, insoluble fibre per group. with either oat or measured daily. cholesterol (wheat) on blood trial bran. Food LDL-C calculated ~10% higher decrease in lipids and weighed before daily and and average lipoproteins and after meals. measured directly participant age 8 Test diet provided on first and last year younger in 13.4 g soluble day of oat group. fibre per day, intervention. Analysis of amount of -glucan and HDL-C covariance not specified. reported as a indicated no 1wk run-in then mean of last 3 effect of these 3wk intervention. days. differences. Statistical analysis by t-test Beck 2010 Parallel To test the 67 overweight females. 3 strata. All Blood lipid Groups Non-significant Power effects of 57 completed, 56 received dietary measured at generally well decrease in calculation incorporating included in final advice for weight accredited matched, except cholesterol, performed for from oat analysis. loss with either no, pathology baseline fasting and HDL-C. weight loss. bran into an 16 in control trial, 21 in moderate or high laboratory. glucose was energy restricted moderate and 19 (of 20 intake of -glucan RMANOVA higher in the diet for weight completions) in the from oat bran. analysis. high -glucan loss. high -glucan group. 12wk intervention. group. Behall 1997 To test the 23 mildly Diets provided Blood lipids Minimised by Significant Data as least over effects of hypercholesterolaemic with added oat measured by design. decrease in total square means. incorporating an subjects (30% male). fibre extract automated and LDL-C, oat fibre extract containing either methods, LDL-C Compared to 7d into the diet on low (1.6-2g) or calculated. decrease in maintenance blood lipids. high (5.9-8.4g) Statistical analysis diet, test diets soluble of covariance. were 5% less energy from fat. 1wk control period followed by 2 x 5wk periods.
Anderson 1991 Parallel To compare effects of soluble (oat) and insoluble fibre (wheat) on blood lipids and lipoproteins 21 males with hypercholesterolaemia. 20 completed study, 10 per group. Conducted in a metabolic ward with food prepared with either oat or bran. Food weighed before and after meals. Test diet provided 13.4 g soluble fibre per day, amount of -glucan not specified. 1wk run-in then 3wk intervention. Intake monitored in metabolic ward. Blood lipids measured daily. LDL-C calculated daily and measured directly on first and last day of intervention. and HDL-C reported as a mean of last 3 days. Statistical analysis by t-test Groups matched for BMI. Baseline cholesterol ~10% higher and average participant age 8 year younger in oat group. Analysis of covariance indicated no effect of these differences. Significant decrease in and LDL-C, decrease in Beck 2010 Parallel To test the effects of incorporating from oat bran into an energy restricted diet for weight loss. 67 overweight females. 57 completed, 56 included in final analysis. 16 in control 21 in moderate and 19 (of 20 completions) in the high -glucan group. 3 strata. All received dietary advice for weight loss with either no, moderate or high intake of -glucan from oat bran. 12wk intervention. Blood lipid measured at accredited pathology laboratory. RMANOVA analysis. Groups generally well matched, except baseline fasting glucose was higher in the high -glucan group. Non-significant decrease in cholesterol, and HDL-C. Power calculation performed for weight loss. Behall 1997 To test the effects of incorporating an oat fibre extract into the diet on blood lipids. 23 mildly hypercholesterolaemic subjects (30% male). Diets provided with added oat fibre extract containing either low (1.6-2g) or high (5.9-8.4g) soluble 1wk control period followed by 2 x 5wk periods. Blood lipids measured by automated methods, LDL-C calculated. Statistical analysis of covariance. Minimised by design. Significant decrease in total and LDL-C, decrease in Data as least square means. Compared to 7d maintenance diet, test diets were 5% less energy from fat. over trial trial,