Table 2 Maternal HIV Parameters and CCI CMV+ CMV- N (row%) N (row%) OR (95% CI) p-value Maternal log10 viral load 1.29 (0.94-1.71) 0.1106 Maternal viral load (copies/mL) >100,00 8 (6.84) 109 (93.16) 2.06 (0.42-10.0) 0.3724 10,000-99,999 36 (7.84) 423 (92.16) 2.38 (0.56-10.2) 0.2408 1,000-9,999 18 (5.81) 292 (94.19) 1.73 (0.39-7.65) 0.4723 400-999 0 (0.00) 45 (100.0) 0.00 (0.00-Inf) 0.9750 0-399 2 (3.45) 56 (96.55) 1.00 Maternal CD4 count (/100 copies/mL) 1.02 (0.94-1.10) 0.7120 Maternal CD4 counts (cells/mL) <350 21 (6.27) 314 (93.73) 0.93 (0.52-1.66) 0.7983 350 to 499 13 (6.25) 195 (93.75) 0.92 (0.47-1.82) 0.8191 500+ 29 (6.73) 402 (93.27) 1.00 Maternal virus load at delivery & maternal CD4 cell counts at delivery were NOT associated with CCI Table 3 Parameters associated with CCI OR (95% CL) p HIV infection status Unknown 5.47 (2.01-14.9) 0.0009 In utero 5.98 (2.96-12.1) <0.0001 Adjusted Intrapartum 1.97 (0.56-6.91) 0.29 multivariate Negative 1.0 Geography logistic US 15.6 (1.26-193) 0.03 regression Brazil 5.14 (1.40-18.8) 0.01 analysis South Africa 1.00 Race Black 1.80 (0.86-3.76) 0.12 Mulatto 1.99 (0.96-4.09) 0.06 White 1.00
Table 2 Maternal HIV Parameters and CCI CMV+ N (row%) CMV- N (row%) OR (95% CI) p-value Maternal log10 viral load Maternal viral load (copies/mL) >100,00 10,000-99,999 1,000-9,999 400-999 0-399 Maternal CD4 count (/100 copies/mL) Maternal CD4 counts (cells/mL) <350 350 to 499 500+ 8 (6.84) 36 (7.84) 18 (5.81) 0 (0.00) 2 (3.45) 21 (6.27) 13 (6.25) 29 (6.73) 109 (93.16) 423 (92.16) 292 (94.19) 45 (100.0) 56 (96.55) 314 (93.73) 195 (93.75) 402 (93.27) 1.29 (0.94-1.71) 2.06 (0.42-10.0) 2.38 (0.56-10.2) 1.73 (0.39-7.65) 0.00 (0.00-Inf) 1.00 1.02 (0.94-1.10) 0.93 (0.52-1.66) 0.92 (0.47-1.82) 1.00 0.1106 0.3724 0.2408 0.4723 0.9750 0.7120 0.7983 0.8191 Maternal virus load at delivery & maternal CD4 cell counts at delivery were NOT associated with CCI Table 3 Parameters associated with CCI OR (95% CL) p HIV infection status Unknown In utero Intrapartum Negative Geography US Brazil South Africa Race Black Mulatto White 5.47 (2.01-14.9) 5.98 (2.96-12.1) 1.97 (0.56-6.91) 1.0 15.6 (1.26-193) 5.14 (1.40-18.8) 1.00 1.80 (0.86-3.76) 1.99 (0.96-4.09) 1.00 0.0009 <0.0001 0.29 0.03 0.01 0.12 0.06 Adjusted multivariate logistic regression analysis