the Purépecha in present-day Michoacán and surrounding areas, and the Aztecs/Mexica, who, from their central capital at Tenochtitlan, dominated much of the centre and south of the country (and the non-Aztec inhabitants of those areas) when Hernán Cortés first landed at Veracruz.
Where was the Aztec's central capital located?
Tenochtitlan