<s>[INST] A patient is allergic to cow milk and has returned to clinic after a period of some days for a follow-up visit. When administered a challenge with 10g of cow milk protein, the patient's IgE antibodies against cow milk protein show an anaphylactic reaction. After obtaining baseline measurements, the patient is treated with 50mg of an Anti-IgE antibody. Following this, another challenge with 10g of cow milk protein is administered. 

Choose the best answer:

1. Anaphylactic reaction will not occur because the Anti-IgE antibody will bind to all the patient's IgE antibodies, leaving no free IgE molecules to bind to the cow milk protein.
2. The anaphylactic reaction will not occur because the Anti-IgE antibody will bind directly to the cow milk protein, thus neutralizing its reactivity in the patient.
3. Anaphylactic reaction will occur but will be less severe due to incomplete binding of the Anti-IgE antibody to the patient's IgE antibodies.
4. Anaphylactic reaction will occur as the Anti-IgE drug would require at least a few days to few weeks to show significant clinical effects.

Which option is the best answer?[/INST]