<s>[INST] This exercise is designed to test your knowledge of ethical and conceptual issues in medical research on human beings. 
A drug company is promoting a new experimental drug for migraines, and there is some urgency since it must be ingested within the first few hours after migraine symptoms begin. Look at the potential biases in the following study designs, and tell me if you would approve the study as is. 

Scenario: In the study design, patients who decided on their own to seek medical attention for migraine within a couple of hours after migraine symptoms began would be compared with patients who also decided on their own to seek medical attention more than 2 hours after the symptoms began. Would you approve this study as is?[/INST]