<s>[INST] Together with my team, I have to investigate the bioaccumulation of a certain substance (food context) and I'm trying to write an experimental protocol. I know that in the literature there are several standardized methods for this type of analysis, e.g., Committee of European Normalization—methods (amongst others), but do you think it is possible, safely and legally, to create a new protocol with modifications, in order to adapt to the instrument and the substance under investigation?[/INST]