A concept of two different reaction zones was proposed based on the FCC reaction mechanism. The concept was used to design a novel reactor with corresponding operation measures. Experiments were conducted on the newly designed pilot-plant riser reactor. In comparison with the conventional FCC at relatively equivalent conversion, the pilot-plant test results showed that the olefin content in the cracked naphtha dropped by 12.4%, and both contents of iso-paraffin and aromatic increased by 6%, and its MON increased by 1.3 units while maintaining the RON of the naphtha unchanged, and its sulfur content reduced by 15% with a significant extension of its induction period for Shengli VGO+VR. The run test results of commercial trial were conformable with the results of pilot-plant test.