Previous experiments with organo-metallic compounds like ferrocene,nickelocene and magnesocene showed that a pure spectrum must be obtained on the residual gas mass analyvser before running successfully on the ion source.In collaboration with the chemistry department of the University of Caen.LCMT-ENSI Caen,the synthesis of these metallocene compounds has been studied to provide enriched isotopic compounds to GANIL's users.The chemical transformation yields were 90%,80% and 43%,respectively.Vanadocene,chromocene,colbatocene and ruthenocene compounds have first been studied with a gas mass analyser and then successfully tested on the ECR 4M ion source at GANIL.Some 15eμA of 51V11+,20eμA of 52Cr11+,22eμA of59Co11+,and 17eμA of 102 Ru11+ were achieved.The comparison between the results obtained on the gas mass analyser and the ion beams provided by the source has allowed us to validate this method of determining whether or not an organo-metallic compound could be a candidate for running on our ECR ion source.As the ECR ion sources are tuned and used alternately on the GANIL injectors,the available time for the tests is rare,so this method could be an alternative for the validation of new compounds.