When james was climbing he experiences a couple of symptoms. The most painful and long lasting was on his hands.  What might have happened to him?\nOptions:\n- calluses\n- loss of oxygen\n- vertigo\n- ascending\n- blisters
A step-by-step solution is:
blisters
Blisters can happen on hands.

Blisters are a symptom.

Blisters are painful and long-lasting.

.

Thus, the answer is blisters