It has been developed a model of the DNA in MATLAB , where it has been taken into account each one of the component atoms. It is possible to have a sequence length of even 10000 basis pairs with the possibility for introducing all types of sequences. It was studied the DNA damage in a single strain and in double strain, SSB and DSB respectively as a product of ionising radiation from X-rays when interacting with the DNA immersed in water. This is a theoretical and experimental study in-vitro  that quantifies the SSB and DSB with respect to different Gy's of radiation, this allows the understanding and prediction about the exact risks of the exposition. It has been developed for energies corresponding to the 17.6 KeV however the energy parameters are also variable which allows the simulation of all type of ionising radiation. For this simulation it is also taken into account the indirect damage as a product of the free electrons and radicals from the water effects. The information of the spatial distribution of the electrones is obtained form Geant4 and afterwards it is implemented in Matlab where rays are created with tri-dimensional random trajectories through Monte Carlo simulations. The experimental confirmation was developed by radiating DNA samples immersed in water with a X-rays unit with Molibdeno targetand it is observed and quantified the damage level through Atomic Force Microscopy (AFM). It was obtained a direct relation between the damage and the radiation dose in the experiment and in the model and it is concluded that for 17.6 KeV the deterioration for interaction is observed very low doses but the mutagenic damage only appears until the 17 Gy .
This paper describes the model for DNA in MATLAB taking into account all of component atoms. In this model, it is possible to generate sequences with length 10000 basis pairs available for introducing all types of sequences. Once the strands are generated, it is studied the DNA damage in the single strand and double strand. The damage are outcomes of ionising radiation of X-rays when interacting with the DNA immersed in water. This is a theoretical and experimental in-vitro study that quantifies the single strand and double strand damage for different doses of radiation. This can be useful to predict the exact risks of expositions to radiations. In simulations, it is taken into account the damage caused by free electrons generated by the effect of the interaction with the water molecules, this is different to the effect considered in radiobiology, where indirect damages are due to chemical reactions. The spatial distribution of the electrons is obtained from Geant4 and here this distribution is used for the creation of rays as three-dimensional random trajectories through Monte Carlo simulations. It is also presented the experimental DNA damage through radiating DNA samples immersed in water with a X-rays unit with Molybdenum target. The damage level is quantified through Atomic Force Microscopy (AFM). It is possible to conclude a direct relation between the damage and the radiation doses with the experimental results .
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