Genevestigator is an online platform enabling researchers to globally explore public and proprietary expression data for research and clinical applications. It 's a software tool developed for biologists and medical researchers to identifynovel  targets and biomarkers, characterise and prioritise candidate genes, and in general to understand which factors cause genes to be regulated. Specifically, gene expression is visualised in the context of tissues, stimuli, drug treatments  , diseases, or genetic modifications. Results are processed from a very large database of manually curatedand quality-controlled microarrays and RNAseq samples from a large variety of tissues and conditions  . Currently, data is available for human, mouse, rat, monkey, pig, dog, drosophila, arabidopsis, barley,  rice, wheat , maize, medicago, tomato, tobacco, moss and soybean. Genevestigator was started in January 2004 by scientists from ETH Zurich and is currently developed and commercialized by Nebion AG. Tool for biologists and medical researchers More than 50 ,000 scientists have registered for GENEVESTIGATOR (mostly biologists) from the animal and plant research areas. Its tools have been used in molecular biology, toxicogenomics, and biomarker discovery/validation . As of 2018, its original articles have been cited more than 3,500 times by researchers using the tools . Three tool sets, each containing several tools , are available : CONDITION SEARCH tools: find conditions that are relevant for your genes of interest GENE SEARCH tools: find genes that are specifically expressed in conditions of interest SIMILARITY SEARCH tools: find genes that are similar within a data space.
Genevestigator is an application consisting of a gene expression database and tools to analyse the data. It exists in two versions, biomedical and plant, depending on the species of the underlying microarray and RNAseq data. It was started in January 2004 by scientists from ETH Zurich and is currently developed and commercialized by Nebion AG. Researchers and scientists from academia and industry use it to identify, characterize and validate novel drug targets and biomarkers, identify appropriate research models and in general to understand how gene expression changes with different treatments. Gene expression database The Genevestigator database comprises transciptomic data from numerous public repositories including GEO, Array Express and renowned cancer research projects as TCGA. Depending on the license agreement, it may also also contain data from private gene expression studies. All data are manually curated , quality-controlled and enriched for sample and experiment descriptions derived from corresponding scientific publications. The number of species from where the samples are derived is constantly increasing . Currently, the biomedical version contains data from human, mouse, rat, monkey, fruitfly and other species and used in biomedical research. Gene expression studies are from various research areas including oncology, immunology, neurology, dermatology and cardiovascular diseases. Samples comprise tissue biopsies and cell lines. The plant version contains both, widely used model species such as arabidopsis and medicago as well as major corp species such as maize, rice, wheat and soybean. Gene expression tools More than 60 ,000 scientists from academia and industry use GENEVESTIGATOR for their work in molecular biology, toxicogenomics, biomarker discovery/validation and further research areas. The original scientific publication has been cited over 3,500 times . The analysis tools are divided into three major sets : CONDITION SEARCH tools: find conditions such as a tissue, disease, treatment or genetic background that regulate the gene(s) of interest GENE SEARCH tools: find genes that are specifically expressed in the condition(s) of interest SIMILARITY SEARCH tools: find genes or conditions that show a similar gene expression pattern
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online platform enabling researchers to globally explore public and proprietary expression data for research and clinical applications. It 's a software tool developed for biologists and medical researchers to identifynovel
application consisting of a gene expression database and tools to analyse the data. It exists in two versions, biomedical and plant, depending on the species of the underlying microarray and RNAseq data. It was started in January 2004 by scientists from ETH Zurich and is currently developed and commercialized by Nebion AG.
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Researchers and scientists from academia and industry use it to identify, characterize and validate novel drug
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characterise and prioritise candidate genes, and
identify appropriate research models and
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which factors cause genes to be regulated. Specifically, gene expression is visualised in the context of tissues, stimuli, drug treatments
how gene expression changes with different treatments.
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Gene expression database The Genevestigator database comprises transciptomic data from numerous public repositories including GEO, Array Express and renowned cancer research projects as TCGA. Depending on the license agreement, it may also also contain data from private gene expression studies. All data are manually curated
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diseases, or genetic modifications. Results are processed from a very large database of manually curatedand
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microarrays and RNAseq samples from a large variety of tissues and conditions
and enriched for sample and experiment descriptions derived from corresponding scientific publications.
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The number of species from where the samples are derived is constantly increasing
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data is available for
the biomedical version contains data from
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pig, dog, drosophila, arabidopsis, barley,
fruitfly and other species and used in biomedical research. Gene expression studies are from various research areas including oncology, immunology, neurology, dermatology and cardiovascular diseases. Samples comprise tissue biopsies and cell lines.
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The plant version contains both, widely used model species such as arabidopsis and medicago as well as major corp species such as maize,
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, maize, medicago, tomato, tobacco, moss
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Genevestigator was started in January 2004 by scientists from ETH Zurich and is currently developed and commercialized by Nebion AG.
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Tool for biologists and medical researchers More than 50
Gene expression tools More than 60
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have registered for GENEVESTIGATOR (mostly biologists) from the animal and plant research areas. Its tools have been used
from academia and industry use GENEVESTIGATOR for their work
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and
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. As of 2018, its original articles have been cited more than
and further research areas. The original scientific publication has been cited over
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by researchers using the tools
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Three tool sets, each containing several tools , are available
The analysis tools are divided into three major sets
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that are relevant for your genes
such as a tissue, disease, treatment or genetic background that regulate the gene(s)
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conditions
the condition(s)
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that are similar within a data space.
or conditions that show a similar gene expression pattern