question: Does the variant on chromosome 20 at location 18527577 affecting gene SEC23B (SEC23 homolog B, COPII coat complex component) have a clinical significance of benign or pathogenic? If pathogenic, what disease(s) is associated?
answer: pathogenic; ['Congenital_dyserythropoietic_anemia', 'Congenital_dyserythropoietic_anemia,_type_II', 'Cowden_syndrome_7']