question: Assess the clinical significance (benign or pathogenic) of the variant at chromosome 15, position 88845544, gene ACAN (aggrecan). What disease(s) is it linked to if pathogenic?
answer: pathogenic; ['Short_stature_and_advanced_bone_age,_with_or_without_early-onset_osteoarthritis_and/or_osteochondritis_dissecans', 'Spondyloepimetaphyseal_dysplasia,_aggrecan_type', 'Spondyloepiphyseal_dysplasia,_Kimberley_type']