question: A genetic alteration at chromosome 4, position 70642685, in gene ENAM (enamelin)—benign or pathogenic? If pathogenic, which disease(s) is involved?
answer: pathogenic; ['Amelogenesis_imperfecta_-_hypoplastic_autosomal_dominant_-_local', 'Amelogenesis_imperfecta_type_1C', 'ENAM-related_disorder']