It has been known for quite some time now that inherited germline mutation in the tumour suppressor genes BRCA 1 and BRCA 2 can increase the likelihood of cancer progression dramatically.
Arfgengar kímlínustökkbreytingar eins og þekktar eru í BRCA 1 og BRCA 2 genunum geta aukið líkur á að krabbamein myndist margfalt.