The head part was synthesized from a commercially available carboxylic acid protected with an ethyl ester or a special orthoester and then lengthened via copper mediated coupling with a propargyl subunit.
Hausinn var smíðaður úr, alkýn karboxýlsýru, sem vernduð var annaðhvort sem etýlester eða s.k. OBO ortho ester og svo lengd með própargýl hóp.