BRCA 2 participates in repair of double stranded breaks in DNA through homologous recombination. Cells deficient in homologous recombination have more genomic instability, which can cause somatic copy number variations (CNVs).
BRCA 2 tekur þátt í við-gerð tvíþátta brota DNA með samstæðri endurröðun, skortur á starfsemi þess eykur óstöðugleika erfðamengisins, sem m.a. getur valdið áunnum DNA eintakafjöldabreyt-ingum (copy number variations, CNVs).