The hypothesis was that the strength of the subunit association is variable depending on the variant and that the dimer association also is dependent on how tightly the magnesium ion in the enzyme reaction site is bound.
Tilgátan var sú að tengsl undireininganna séu missterk eftir því hvaða afbrigði eigi í hlut og að tengslin séu einnig háð því hversu fast magnesíumjónin í hvarfstöð ensímsins binst.