However, tissues are ensembles of cells that may each have their own epigenetic profile and therefore inter-individual difference in cellular heterogeneity may compromise these studies.
Vefir eru hins vegar samsettir úr fjölda frumutegunda sem hver um sig hefur mögulega einkennandi utangenaerðamerki og þar af leiðandi getur breytileyki í hlutfallslegum frumufjölda milli einstaklinga gruggað (e.confound) þessar rannsóknir.