A single region located in an intragenic CpG island in the HHEX gene was selected for further study, and comparing DNAm levels between 214 cases and 164 controls, lower average DNAm levels were observed in individuals with T 2 DM.
Eitt svæðanna, sem staðsett er í CpG eyju innan HHEX gensins, var valið til frekari skoðunar. Lægri meðaltals DNA metýlun greindist í einstaklingum með SST 2 í þessu svæði þegar 214 sykursjúkir og 164 einstaklingar án sjúkdómsins voru bornir saman.