The development of melanocytes and melanoma depends on the presence of the microphthalmia-associated transcription factor (MITF), a member of the basic helix-loop-helix-leucine zipper (bHLH-LZ) transcription factor family.
Þroskun litfruma og myndun sortuæxla er háð umritunarþættinum microphthal-mia associated transcription factor (MITF) en hann tilheyrir basic-helix-loop-helix leucine zipper (bHLH-LZ) fjölskyldunni.