In the AQUIR 47E, mutant which, the mutation was supposed to eliminate a putative salt bridge between R 47-D 212 as well as to exchange the charge at this surface location.
Stökkbreytingunni AQUIR 47E var ætlað að taka út mögulega saltbrú á milli R 47-D 212 og að skipta um yfirborðshleðslu.