warkany syndrome 2, also known as chromosome 8 trisomy syndrome or trisomy 8, is a condition where chromosome 8 in humans has three sets of chromosomes, as opposed to the normal two. this condition is called "trisomy", and is where warkany syndrome 2 derives its alternative names. people born with warkany syndrome 2 typically have mental retardation and renal or skeletal malformations.