if we followed the rules  er the m r c rules strictly  one of the lower risk group of patients was a g three p t one tumour and that patient er progressed and in fact all the patients who progressed, all the four out of the hundred and fifty nine patients who progressed erm from the total group had either g two or g three p t one tumours at diagnosis, and i think there's a very strong case for making these a totally separate group of patients erm for follow up.