ciclosporin exhibits very poor solubility in water, and, as a consequence, suspension and emulsion forms of the medication have been developed for oral administration and for injection. ciclosporin was originally brought to market by sandoz (now novartis), under the brand name sandimmune, which is available as soft gelatin capsules, an oral solution, and a formulation for intravenous administration. these are all nonaqueous compositions. a newer microemulsion, orally-administered formulation, neoral, is available as a solution and as soft gelatin capsules. the neoral compositions are designed to form microemulsions in contact with water.