east of there, the road runs along small portion of the border with valdosta becoming west hill avenue then enters it completely just before encountering the quarter cloverleaf interchange with interstate 75 at exit 16, and from there also serves as the beginning of the interstate 75 business loop. us 84/221/i-bus 75/sr 83 makes a brief curve to the southeast before the intersection with the southern terminus of sr 133. after crossing over a railroad bridge and then intersecting north wells street, the routes become a one-way pair splitting between hill avenue (eastbound) and central avenue (westbound). further downtown, us 84/221/sr 38 encounters another one-way pair at us 41 business, the southbound road uses north patterson street, and the northbound road which is a block later is at north ashley street, which takes i-bl 75 with it. west hill and west central avenues become east hill and east central avenues east of patterson street. central avenue ends at hill avenue and forrest street making the routes bidirectional four-lane undivided highway with center-left turn provisions once again. after blanchard street, the road becomes a divided highway just before crossing a pair of bridges over knights creek, then passes by some radio towers for wjem (1150 am). the end of us 221's multiplex with us 84/sr 38 takes place at the intersection with us 41/srs 7/31 (inner perimeter road), and us 221 turns north along a new multiplex. after a curve to the northwest, the four routes intersect east park avenue. here, us 221/sr 31 split off to the northeast and then leaves the city, while us 41/sr 7 heads northwest towards i-75 at exit 22. east park avenue runs northeast becoming lakeland highway, and passes through spares residencies and occasional farm fields of little importance. the only site of any significance along this route is the bemiss auxiliary army airfield which is hidden off in a wooden area accessible only by a dirt road just south of the lowndes-lanier county line.