duffy made her film debut playing the character of sissy in the 2010 drama film "patagonia", directed by marc evans. sissy's character is "a welsh student who livens up the holiday of a young argentinian man on a trip to wales". the film is about welsh argentines living in y wladfa, patagonia. "patagonia" premiered at the seattle international film festival on 10 june 2010, and was released in october 2010.