some stis can also be spread in ways other than having sex. for example, herpes simplex and hepatitis b could be caught by a virgin without having sex, but can also be caught through sex. some types of stis can spread from contact between the genitals, mouth, anus, skin, eyes, and (rarely) infected surfaces; this depends a lot on the type of sti and how it spreads. some common diseases like hpv can cause warts and cancer in the genitals or anus or throat.