many specific groups have been targeted for studying the effects of reminiscence therapy and were evaluated using different measures based on their previously existing condition and the problems associated with it. those ranking higher in their depression rating showed a greater rate of improvement of their symptoms compared to those exhibiting less depressive symptoms before the therapy began, although improvements were seen across depression levels. across studies, reminiscence therapy positively influenced patients with dementia evaluated using various measures specifically in vascular dementia, cortical glucose metabolism increase in areas important for social interaction and remote memories. those with alzheimer's disease had improved blood flow to areas in brain, as previously discussed, and positive changes in evaluated behavioural traits. in patients with leprosy, the greatest positive effects were seen in those with depression but reminiscence therapy did not effect the stage of dementia or cognitive scores.