while the art can be incredibly realistic or cartoonish, characters often have large eyes (female characters usually have larger eyes than male characters), small noses, tiny mouths, and flat faces. psychological and social research on facial attractiveness has pointed out that the presence of childlike facial features increases attractiveness. manga artists often play on this to increase the appeal of protagonists. large eyes have become a permanent fixture in manga and anime since the 1960s when osamu tezuka was inspired by disney cartoons from the united states and started drawing them in this way.