the terence v. powderly house is a historic house at 614 north main avenue in scranton, pennsylvania, united states. it was the home of terence v. powderly (1849-1924) from his early life until 1921. during this time he led the knights of labor, an early but unsuccessful attempt to establish a broad-based labor union. he also served as mayor of scranton for several terms. it was designated a national historic landmark in 1966. it has remained a private residence and is not open to the public.