when ms. deter died of septicemia on 8 april 1906, alzheimer was informed and her brain was sent to munich for him to study. studying samples of her brain under a microscope he noticed neurofibriallry tangles and bundles made up of beta-amyloid plaque, which are two of the main features of the disease. on 3 november 1906, alzheimer presented the results of his findings in auguste's case at the conference of south-west german psychiatrists in tübingen, and he published his findings in the case in 1907.