the married life was short and not happy. 20-year-old isabella had to deal with 52-year-old husband who complained of gout and overall ill health. in spring 1540, zápolya traveled to quell a revolt in transylvania by . isabella stayed in buda as she was pregnant. their son john sigismund zápolya was born on 7 july 1540. zápolya succeeded in subduing the rebels, but he died on 22 july from cerebral hemorrhage.