the 1958 iowa state cyclones football team represented iowa state college of agricultural and mechanic arts (renamed iowa state university in 1959) in the big seven conference during the 1958 ncaa university division football season. in their first year under head coach clay stapleton, the cyclones compiled a 4–6 record (0–6 against conference opponents), finished in last place in the conference, and outscored their opponents by a combined total of 127 to 88. they played their home games at clyde williams field in ames, iowa.