bis-choline tetrathiomolybdate (or tiomolibdate usan, trade name decuprate), is a salt of tetrathiomolybdate (ttm, mos) and choline currently under investigation as a therapy against wilson's disease, a rare and potentially fatal disease in which the body cannot regulate copper. wilson's disease is an autosomal recessive genetic disorder that is manifested by serious hepatic, neurologic or psychiatric symptoms. the disease is fatal if left undiagnosed and untreated. it is estimated that approximately 1 individual in every 30,000 worldwide have wilson's disease, corresponding to approximately 15,000 individuals in the european union and approximately 11,000 in the united states.