thiamine transporter 1, also known as thiamine carrier 1 (tc1) or solute carrier family 19 member 2 (slc19a2) is a protein that in humans is encoded by the "slc19a2" gene. slc19a2 is a thiamine transporter. mutations in this gene cause thiamine-responsive megaloblastic anemia syndrome (trma), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness.