the optimal variable subspace and approximation model found by a cop/mop procedure can also be used for a pre-optimization before global optimizers (evolutionary algorithms, adaptive response surface methods, gradient-based methods, biological-based methods) are used for a direct single-objective optimization. after conducting a sensitivity analysis using mop/cop, also a multi-objective optimization can be performed to determine the optimization potential within opposing objectives and to derive suitable weighting factors for a following single-objective optimization. finally this single-objective optimization determines an optimal design.