pyelonephritis (kidney infection) is treated more aggressively than a simple bladder infection using either a longer course of oral antibiotics or intravenous antibiotics. seven days of the oral fluoroquinolone ciprofloxacin is typically used in geographic areas where the resistance rate is less than 10%. if the local resistance rates are greater than 10%, a dose of intravenous ceftriaxone often is prescribed. people with more severe symptoms are sometimes admitted a hospital for ongoing antibiotics. if symptoms do not improve following two or three days of treatment, it can mean that the urinary tract is blocked by a kidney stone.