gemident was developed at stanford university by adam kapelner from june, 2006 until january, 2007 in the lab of dr. peter lee under the tutelage of professor susan holmes. the concept was inspired by data kohrt et al. who analyzed immune profiles of lymph nodes in breast cancer patients. hence, gemident works well when identifying cells in ihc-stained tissue imaged via automated light microscopy when the nuclear background stain and membrane/cytoplasmic stain are well-defined. in 2008, it was adapted to support multispectral imaging techniques.