after their move to the american league, the houston astros signed bédard to a minor-league deal on january 21, 2013. he recorded his first career save on opening day, march 31, 2013 with 3 1/3 innings of relief against rival texas rangers. on july 21, 2013, he pitched 6 and 1/3 innings of a no hitter when he asked to leave his no-hitter after 109 pitches. in 32 appearances (26 starts) for the astros, he was 4–12 with a 4.59 era.