clinical presentation of an infection is ill-defined, but most individuals may present a skin rash and flu like symptoms, such as elevated body temperature and fatigue. in more severe infections, such as in immunodeficient individuals, peritonitis and pleuritis, and may lead to multi-organ failure. in the case of invasive infections, surgical intervention may be required to remove fungal mass from body tissues. due to limited, ill-defined cases and the variance in clinical presentation and species identification, no optimal treatments are available. "a. strictum" and other "acremonium" species are generally resistant to most antifungals, but antifungal susceptibility testing is recommended to select the most appropriate treatment for the strain of "a. strictum" that is the infection agent. amphotericin b therapy coupled with ketoconazole is usually recommended as the best available treatment.