deletion of the "trpc4" gene decreases levels of sociability in a social exploration task. these results suggest that trpc4 may play a role in regulating social anxiety in a number of different disorders. however deletion of the trpc4 gene had no impact on basic or complex strategic learning. given that the trpc4 gene is expressed in a select population of midbrain dopamine neurons it has been proposed that is may have an important role in dopamine related processes including addiction and attention.