vascular (or arterial) claudication typically occurs after activity or ambulation for a distance with resultant vascular insufficiency (lack of blood flow) where the muscular demands of oxygen outweighs the supply. symptoms are lower extremity cramping. resting from activity even in a standing position may help relieve the symptoms. spinal or neurogenic claudication may be differentiated from arterial claudication based on activity and position. in neurogenic claudication, positional changes lead to increased stenosis (narrowing) of the spinal canal and compression of nerve roots and resultant lower extremity symptoms. standing and extension of the spine narrows the spinal canal diameter. sitting and flexion of the spine increases spinal canal diameter. a person with neurogenic claudication will have worsening of leg cramping with standing erect or standing and walking. symptoms may be relieved by sitting down (flexing the spine) or even by walking while leaning over (flexion of the spine) a shopping cart.