victor babeş discovered more than 50 germs and a cure for a disease named after him, babesiosis; biologist nicolae paulescu discovered insulin. another biologist, emil palade, received the nobel prize for his contributions to cell biology. george constantinescu created the theory of sonics, while lazăr edeleanu was the first chemist to synthesize amphetamine and also invented the modern method of refining crude oil. costin neniţescu found new methods for the synthesis of pirilium salts, of carbenes, tryptamine, serotonin, two new syntheses for the indole nucleus, and a new method of polymerisation of ethylene.