state route 46 (sr 46) is a state highway in cleburne county in the eastern part of the u.s. state of alabama. the western terminus of the highway is at an intersection with u.s. route 78 (us 78) (which also carries the unsigned sr 4) in heflin. the eastern terminus of the route is at the georgia state line, east of ranburne, where the roadway continues as georgia state route 166.