as a member of the athens organizing committee for the olympic games, karyofylli was a part of the planning to make transportation in athens more accessible for paralympic competitors. in 2005, karyoflli was elected as a member of the european paralympic committee. in 2009, karyofylli was nominated to be a member of the ipc, but she was not elected. outside of her career in sports development, karyofylli was the head of mission for greece at the 2013 mediterranean games. in 2014, she was selected for a five year term as a city councillor for nea smyrni.