grandma wolfe was the deceased grandmother on george's side of the family and the rude wife of hiram wolfe and the grandmother of heffer, cindy, and peter. she appears to be very old and bitter and has no soul, as she is spending her afterlife in heck. in the episode "heff in a handbasket", when peaches tried to keep heffer in heck for all eternity after he sold his soul, he is stopped by grandma wolfe who refuses to spend her afterlife with heffer, and she eats his contract. she is voiced by tom kenny.