in march 2015, ruth negga was cast as tulip o'hare, the ex-girlfriend of jesse custer, and joe gilgun was cast as cassidy, an irish vampire and the best friend of custer. in april 2015, lucy griffiths was cast as emily woodrow, a character described as a no-nonsense single mother of three who is a waitress, the church organist, bookkeeper and jesse's loyal right hand." also in april, it was confirmed that dominic cooper would play custer.