the 1964 iowa state cyclones football team represented iowa state university in the big eight conference during the 1964 ncaa university division football season. in their seventh year under head coach clay stapleton, the cyclones compiled a 1–8–1 record (0–7 against conference opponents), finished in last place in the conference, and were outscored by opponents by a combined total of 155 to 72. they played their home games at clyde williams field in ames, iowa.