pharmacological methods of treatment include fludrocortisone, midodrine, somatostatin, erythropoietin, and other vasopressor agents. however, often a patient with pure autonomic failure can mitigate his or her symptoms with far less costly means. compressing the legs and lower body, through crossing the legs, squatting, or the use of compression stockings can help. use of an abdominal binder is even more effective. also, ingesting more water than usual can increase blood pressure and relieve some symptoms.