the virus is one of a group of mosquito-borne or arthropod-borne viruses, also called arboviruses, that can cause fever and meningitis or meningoencephalitis, mostly in adults. jamestown canyon virus disease is relatively rare; in the united states, the cdc found only 31 disease cases from 2000 to 2013, but it is likely under-recognized and probably endemic throughout most of the united states.