An Update On Dianna's Health

Some information about MECFS:

MECFS is one of the most poorly funded illnesses in terms of research despite it being known about for decades. There is no known cure and no established successful treatments.

Life expectancy for people with MECFS is around 20 years below the average.

MECFS affects women more than men - the ratio is about 4 to 1.

It is believed that many different viruses/bacteria can lead to MECFS. Some people with MECFS say their illness started with an intestinal infection, some with respiratory infections (like from Covid-19), some from bacterial infections such as from the bacteria carried by ticks that can cause Lyme disease. It is also thought there me be a hereditary link with MECFS.

MECFS ranges in severity from mild to very severe. People with mild MECFS are sometimes still able to work in some capacity but are forced to reduce working hours and social life. Dianne appears to have developed a very severe form of MECFS. People who are very severe are generally bed bound, need help going to the bathroom, and are unable to feed themselves so have to be tube fed.

Some research suggests MECFS involves a broken or poorly functioning aerobic energy system which results in an over-reliance on anerobic energy systems. People with MECFS appear to be permanently hovering around or beyond anaerobic exhaustion. Normal energy pathways in the TCA (Krebs) cycle inside mitochondria appear to be in some way blocked or malfunctioning.

Some hypotheses suggest MECFS is an immune disease where the immune system is permanently stuck in the on position.

There are numerous symptoms other than fatigue that are associated with MECFS including nausea, dizziness, light and sound sensitivity, orthostatic intolerance, POTS, PEM (post exertional malaise), fibromyalgia, unrefreshing sleep, brain fog and other cognitive and memory problems.

Long Covid has its own pathology associated with it on top of the MECFS ones mentioned above such as reduced blood flow caused by microclotting in the blood and damaged endothelium which potentially adds to symptoms.

Please share the video and help the world become more aware of this cruel, life destroying illness and if possible help with campaigning for increased research funding.