The ever-increasing amount of information flowing through Social Media presents numerous opportunities for the generation of Business Intelligence. Challenges exist in the leveraging of these data sources due to their heterogeneity and unstructured content. This paper presents the application of Semantic Computing to Social Media for industrial application, focusing on topic identification and behavior prediction. The methodologies described can benefit many areas of an organization including support of marketing, customer service, engineering and public relations. Results demonstrate that business operations can be substantially enhanced through application of Semantic Computing to Social Media.