We provide a platform SaaS so generate emails on behalf of our customers to their customers.While our spam rate is very low, at least 2/3's of the spam reports we do get are for what appear to be totally legitimate transactional emails (eg. purchase receipts).  Some could be typo's in an email address but I suspect the majority are misclicks on the end users part.Currently we unsubscribe all spam reporting addresses from all emails which causes some problems with support questions as to why people aren't getting emails they then expect as follow ups.How do people handle this: treat all spam reports as a hard 'never-going-to-email-you-again' to protect your email reputation or continue to send high priority transactional emails regardless, or ???