Segment Assets We manage our assets on a total company basis, not by operating segment. Therefore, our chief operating decision maker does not regularly review any asset information by operating segment and, accordingly, we do not report asset information by operating segment. Earnings Depreciation and Amortization (a) Three Months Ended Three Months Ended June 30, June 30, (MILLIONS OF DOLLARS) 2019 2018 2019 2018 U.S. Revenue $ 780 $ 677 Cost of sales 158 140 Gross profit 622 537 Gross margin 79.7 % 79.3 % Operating expenses 127 116 Other (income)/deductions   U.S. Earnings 495 421 $ 9 $ 8 International Revenue (b) 742 728 Cost of sales 218 229 Gross profit 524 499 Gross margin 70.6 % 68.5 % Operating expenses 146 147 Other (income)/deductions  2 International Earnings 378 350 12 12 Total operating segments 873 771 21 20 Other business activities (79 ) (82 ) 6 6 Reconciling Items: Corporate (178 ) (139 ) 16 14 Purchase accounting adjustments (58 ) (23 ) 55 22 Acquisition-related costs (22 )    Certain significant items (c) (3 ) (7 )   Other unallocated (78 ) (83 )  1 Total Earnings (d) $ 455 $ 437 $ 98 $ 63 (a) Certain production facilities are shared. Depreciation and amortization is allocated to the reportable operating segments based on estimates of where the benefits of the related assets are realized. (b) Revenue denominated in euros was $184 million and $191 million for the three months ended June 30, 2019 , and June 30, 2018 , respectively. (c) For the three months ended June 30, 2019 , primarily represents product transfer costs and consulting fees related to our supply network strategy. For the three months ended June 30, 2018 primarily represents: (i) employee termination costs of $1 million related to our operational efficiency initiative, (ii) consulting fees and exit costs of $3 million related to our supply network strategy, and (iii) employee termination costs of $3 million in Europe as a result of initiatives to better align our organization structure. (d) Defined as income before provision for taxes on income. Earnings Depreciation and Amortization (a) Six Months Ended Six Months Ended June 30, June 30, (MILLIONS OF DOLLARS) 2019 2018 2019 2018 U.S. Revenue $ 1,498 $ 1,311 Cost of sales 305 280 Gross profit 1,193 1,031 Gross margin 79.6 % 78.6 % Operating expenses 237 212 Other (income)/deductions   U.S. Earnings 956 819 $ 19 $ 16 International Revenue (b) 1,460 1,454 Cost of sales 428 463 Gross profit 1,032 991 Gross margin 70.7 % 68.2 % Operating expenses 278 280 Other (income)/deductions  3 International Earnings 754 708 25 23 Total operating segments 1,710 1,527 44 39 Other business activities (159 ) (163 ) 11 11 Reconciling Items: Corporate (340 ) (292 ) 30 27 Purchase accounting adjustments (124 ) (46 ) 110 45 Acquisition-related costs (27 ) (1 )   Certain significant items (c) (73 ) (10 )   Other unallocated (151 ) (161 ) 1 1 Total Earnings (d) $ 836 $ 854 $ 196 $ 123 (a) Certain production facilities are shared. Depreciation and amortization is allocated to the reportable operating segments based on estimates of where the benefits of the related assets are realized. (b) Revenue denominated in euros was $365 million and $375 million for the six months ended June 30, 2019 , and June 30, 2018 , respectively. (c) For the six months ended June 30, 2019 , primarily represents a change in estimate related to inventory costing of $68 million , and product transfer costs and consulting fees of $5 million related to our supply network strategy. For the six months ended June 30, 2018 , primarily represents: (i) employee termination costs of $1 million related to our operational efficiency initiative, (ii) consulting fees, employee termination costs and exit costs of $5 million related to our supply network strategy, and (iii) employee termination costs of $3 million in Europe as a result of initiatives to better align our organization structure, and (iv) a charge of $1 million related to the implementation of new accounting guidance as a result of the enactment of the Tax Act. (d) Defined as income before provision for taxes on income.