This thesis explores the convergence of four different &amp;lsquo;bios&amp;rsquo; (biology, biopolicy, biotechnology and the biosphere) and the way their imminent and accelerating interaction results in a closed system model of biospheric entropy generation par excellence. By highlighting the nature of these convergences I seek to explore ways of negating and/or reversing this oxymoronic, &amp;lsquo;end driven&amp;rsquo; terminal logic, using generative approaches to &amp;ldquo;futuring&amp;rdquo; (Fry, 2009a) from contemporary art and design. I build on these approaches by targeting, as contemporary biopolitical interventions do, the individual &amp;lsquo;self&amp;rsquo; as the most salient agent capable of making transformative change. In this capacity I suggest that the soundest means to &amp;lsquo;construct&amp;rsquo; the future (&amp;ldquo;where it can no longer be assumed that we, en masse, have a future&amp;rdquo; (Fry, 2009a: 1)) is via the &amp;lsquo;deregulation&amp;rsquo; of the self.   Institutional and ideological deregulation will enable the species to spontaneously self-organise and (re) &amp;lsquo;construct&amp;rsquo;, albeit differently, the emergent conditions for life. By facilitating the exploration of idiosyncrasy and creativity to the nth degree, deregulation cultivates difference, diversity and unpredictability, qualities herein identified as key antidotes to biospheric entropy. The rise of &amp;lsquo;Do It Yourself&amp;rsquo; (DIY) cultures &amp;ndash; in particular the advent of DIY synthetic biology &amp;ndash; are the driving inspirations behind this hypothesis, with the core claim being that the individual artist (the deregulated self) is the best equipped to exploit such DIY cultures to the collective advantage of the species; that is, toward the construction of a &amp;ldquo;futuring&amp;rdquo; condition