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# Fatty liver and cirrhosis are a threat to your health
### Fatty Liver & Liver Cirrhosis Are At Epidemic Levels!
* 100,000,000 Americans have a fatty liver.  Most don't know it.
* 20,000,000 will develop liver fibrosis disease or NAFLD (nonalcoholic fatty liver disease) as a result.
* 5,000,000 million will progress to liver cirrhosis or NASH (nonalcoholic steatohepatitis) and possibly end stage liver failure.
* Some will be lucky enough to be listed for a transplant, the only cure for late stage liver disease, but 30% of those listed will die waiting.  Death by liver failure is long and difficult.
* We want to help you avoid this kind of death by helping you understand how you may be killing yourself slowly.  And, what you can do about it.
* If you are already ill, we will do our best to help you with that process.
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### Our Mission
***To improve the diagnosis, treatment & support of Americans with fatty liver, NAFLD or NASH through awareness, education, screening and patient advocacy.***
### We Advocate Early Screening
Typically, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are silent diseases.  *They have no symptoms.* Even if cirrhosis has developed, there are often no symptoms until the liver has become so damaged that the only option is a liver transplant.
There *is* currently a quick, easy and economical method to screen for fatty liver disease called transient elastography. The Fatty Liver Foundation is championing a nationwide program to provide liver screening services to make it possible for people who have a concern for their liver health to get an inexpensive scan.
If you would like to watch some very good videos about liver disease,
### ****
Fatty Liver Foundation copyright 2025 all rights reserved
The information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information should not be used as a substitute for professional diagnosis or treatment. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. The Fatty Liver Foundation, its officers or contributors expressly disclaim responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site.
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## clinical trials
Clinical Trial Overview
!
Clinical Trial Finder
**If you have diabetes and are overweight, you can have silent liver disease too**
Learn about fatty liver disease and NASH, and see if you may qualify for a clinical trial.
**About NASH**
If you have diabetes or struggle with your weight, you may have fatty liver disease. A severe form of fatty liver disease, called nonalcoholic steatohepatitis (NASH), often has no symptoms but can cause significant damage to your liver if not diagnosed early.
**About the Clinical Trial**
The MK-3655 Clinical Trial is evaluating the safety and effectiveness of MK-3655, an investigational medication for people with NASH. This trial will test MK-3655 compared to placebo. A placebo looks like the study medication but contains no active ingredient.
**You may be able to participate if you: \***
* Are a male or postmenopausal female, 18 to 80 years of age [in Japan: 20 to 80 years of age]
* Have NASH confirmed by a liver biopsy
* Do not have type 2 diabetes OR have type 2 diabetes that is well controlled by diet or a stable dose of diabetes medication
* Have had a stable weight for at least 3 months
**If you qualify and decide to participate:**
* Your liver and your overall health will be monitored closely by an experienced study team
* You will receive the investigational medication and study-related doctor visits at no charge
* The information gathered may help advance medical knowledge about NASH and may improve patient care in the future
* Participation is voluntary and you are free to withdraw from the study at any time. Your privacy will be maintained throughout the clinical trial
To learn more, including the possible risks and benefits of participation, visit .
For a copy of this information, you can download .
*\*There may be additional requirements to participate. The study doctor can provide you with more information. Additional potential risks and benefits will be fully described to you by your study team.*
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