Built as a successor to the 342 America, The 375 used the new 4.5 L (4,522 cc) "long block" Lampredi designed V12 engine that produced up to 300 horsepower at 6300 rpm, with three Weber 40DCF (or DCZ) carburettors, and allowed it do 0-60 mph in under seven seconds and reach a top speed of almost 160 mph (257.5 kmh).