Despite the change in Fret of only 35% across the pathophysiological range (possibly 40% maximum change form no glucose to saturation), the sensor has been shown to decrease in functionality by only 20% after 450 days incubation at 37 °C and to monitor glucose as well as the Medtronic/Minimed CGMS sensor in animal models (mouse, pig, and dog); however their stated aim is to create a smart tattoo.