text: Funding for this research was provided by:
  Science and Technology Key Project Foundation of Henan Province (132102110126)
  National Natural Science Foundation of China (U1504326)
  Received: 1 March 2018
  Accepted: 29 October 2018
  First Online: 12 November 2018
  Ethics approval and consent to participate
  : All animal experiments were performed in accordance with the principles in the Chinese law on the humane use of animals for scientific use, and approved by the Institutional Animal Care and Use Committee in Tsinghua University with the animal protocol number 14-ZJR1.
  : Not applicable
  : The authors declare that they have no competing interests.
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