In his final year - 2004 - they finished in 3rd place again , and this time they reached the playoff final , but lost to Brighton & Hove Albion .


He was sacked within days and replaced by veteran player Brian Tinnion .


Yeovil Town manager Gary Johnson was recruited as his successor .


Assistant manager Keith Millen took charge as caretaker manager , and led a series of good results , resulting in a second successive tenth-place finish .


The battle for the last playoff spot came down to the final day , before Derby County managed to win their final game and clinch it .


His assistant , Dean Holden , was appointed as his replacement on 10 August 2020 .


Plymouth Argyle have also previously been considered rivals despite a distance of over 100 miles .


Their location and record-breaking salary offer lured star Huddersfield Town manager Herbert Chapman in 1925 .


His permanent replacement , Bruce Rioch , lasted for only one season , leaving the club after a dispute with the board of directors .


His final home match in charge was a 5 – 0 win over Burnley where his entrance was met to a standing ovation by supporters .


He would become the club 's first ever ' head coach ' , while also their second ever manager from outside the United Kingdom .


Former player and assistant first team coach Freddie Ljungberg was appointed as the interim head-coach .


Ivan Gazidis has been the club 's Chief executive since 2009 .


having surpassed Ian Wright 's total of 185 in October 2005 .


Some bioterrorism agents , like the smallpox virus , can be spread from person to person and some , like anthrax , cannot .


However , technologists such as Bill Joy have warned of the potential power which genetic engineering might place in the hands of future bio-terrorists .


In Oregon in 1984 , followers of the Bhagwan Shree Rajneesh attempted to control a local election by incapacitating the local population .


In September and October 2001 , several cases of anthrax broke out in the United States , apparently deliberately caused .


Health-related data such as that from hospital computer systems , clinical laboratories , electronic health record systems , medical examiner record-keeping systems , 911 call center computers , and veterinary medical record systems could be of help ; researchers are also considering the utility of data generated by ranching and feedlot operations , food processors , drinking water systems , school attendance recording , and physiologic monitors , among others .


In 299 he sacked their capital , Ctesiphon .


His palace eventually became the core of the modern-day city of Split in Croatia .


The modern historian Timothy Barnes takes his official birthday , 22 December , as his actual birthdate .


Augustus , the first Emperor , had nominally shared power with his colleagues , and more formal offices of Co-Emperor had existed from Marcus Aurelius onward .


There may have been a revolt in the eastern provinces at this time , as he brought settlers from Asia to populate emptied farmlands in Thrace .


He sought to identify himself with the warlike kings Ardashir ( r .


241 – 72 ) , who had defeated and imprisoned Emperor Valerian ( r .


The executions continued until at least 24 April 303 , when six individuals , including the bishop Anthimus , were decapitated .


The palace is preserved in great part to this day and forms the historic core of Split , the second-largest city of modern Croatia .


It entered service in 1997 as the second aircraft designed to have advanced stealth technology after the Lockheed F-117 Nighthawk attack aircraft .


In 1979 , designer Hal Markarian produced a sketch of the aircraft , that bore considerable similarities to the final design .


MIT engineers and scientists helped assess the mission effectiveness of the aircraft under a five-year classified contract during the 1980 s .


In 2010 , it was made public that the Air Force Research Laboratory had developed a new material to be used on the part of the wing trailing edge subject to engine exhaust , replacing existing material that quickly degraded .


Advanced training is conducted at the USAF Weapons School .


This technique , known as " continuous curvature " , was made possible by advances in computational fluid dynamics , and first tested on the Northrop Tacit Blue .


The use of JDAMs and precision-guided munitions effectively replaced the controversial tactic of carpet-bombing , which had been harshly criticized due to it causing indiscriminate civilian casualties in prior conflicts , such as the 1991 Gulf War .


During the Enlightenment , some thinkers continued to accept reason , along with features of the natural world , as a valid source of religious knowledge , but they rejected the validity of revelation .


This was the age of the Scientific Revolution ; some were animated by a new-found respect for science ( " natural philosophy " ) accompanied by a repugnance for superstition , irrationality , and nonsense .


This position became less and less plausible as thinkers such as David Hume began studying the natural history of religion and suggested that the origins of religion lay not in reason but in emotions such as the fear of the unknown .


Benjamin Franklin believed in reincarnation or resurrection .


Thomas Paine believed in the " probability " of immortality of the soul .


Some , such as Anthony Collins , actually were necessitarians .


Views differ on whether David Hume was a deist , an atheist , or something else .


They are the second-largest rodent in the world ( after the capybara ) .


In the same year , it was estimated that several dozen beavers live within the city limits of Vancouver .


This behavior is common and is seen in many other animal species , such as the elephant and fathead minnow .


He reasoned that if human civilization expanded energy demands long enough , there would come a time when it demanded the " total " energy output of the Sun .


George Dvorsky has advocated the use of self-replicating robots to overcome this limitation in the relatively near term .


Theoretically , any gas giant could be enclosed in a solid shell ; at a certain radius the surface gravity would be terrestrial , and energy could be provided by tapping the thermal energy of the planet .


Smaller bears climb trees to obtain mast ( edible reproductive parts , such as acorns ) .


Bears reach sexual maturity shortly after they disperse ; at around 3 – 6 years depending on the species .


Evidence of her worship has notably been found at Bern , itself named for the bear .


The call consists of weak staccato , chirping whistles , " kleek kik ik ik ik " , somewhat similar in cadence to a gull 's call .


In Southeast Alaska , fish comprise approximately 66 % of the year-around diet of bald eagles and 78 % of the prey brought to the nest by the parents .


For some time , the stronghold breeding population of bald eagles in the lower 48 states was in Florida , where over a thousand pairs have held on while populations in other states were significantly reduced by DDT use .


The bald eagle is the national bird of the United States of America .


The actual eagle has a much softer , chirpy voice , not in keeping with its popular image ; the call of the red-tailed hawk is often substituted in movies and television .


Commonly hunted game included deer , bear , bison , and wild turkey .


A number of fats and oils made from animals served to cook much of the colonial foods .


Many tribes would preserve their meat in the form of pemmican , needed greatly on long journeys or to survive harsh winters .


These included dishes such as stew and fish fried in olive oil , beef and bean stews , almond puddings , and egg custards .


Commonly hunted game included deer , bear , buffalo , and wild turkey .


Many homes had a sack made of deerskin filled with bear oil for cooking , while solidified bear fat resembled shortening .


Rendered pork fat made the most popular cooking medium , especially from the cooking of bacon .


The colonists enjoyed butter in cooking as well , but it was rare prior to the American Revolution , as cattle were not yet plentiful .


People had biscuits as part of their breakfast , along with healthy portions of pork .


If the family did n't grow wheat , then flour would also be purchased .


Another luxury was canned salmon , which was sometimes eaten for Sunday dinner .


Items purchased at the general store would be paid for with eggs , butter or some other food from the farm .


One contemporary writer from Michigan described October as cider season , when apple butter would be made .


Typical farmhouse fare included fried chicken , simmered green beans , boiled corn , chicken and dumplings , fried ham , boiled beans and beets , stewed tomatoes , potatoes , and coleslaw made of shredded cabbage .


Pork scraps and corn meal were cooked into a thick porridge and molded in loaf pans .


Pasteurization , homogenization , evaporation , condensation , and refrigeration along with glass milk bottles , wax paper cartons , and then plastic bottles made milk increasingly available and safe for urban consumers .


Fast food restaurants with standardized product and franchised service models began to appear and spread with the development of the highway system .


Franchising was introduced in 1921 by A&W Root Beer .


From 1912 to the end of the 1930 s researchers discovered and popularized the role of various vitamins and minerals in human health .


Synthetic thiamin ( vitamin B1 ) first became available after 1936 and bakers began voluntarily enriching bread with high-vitamin yeast or synthetic vitamins in the late 1930 s .


Examples include powdered milk , powdered eggs , potato flakes , and frozen concentrated orange juice .


One such example is the TV dinner in which a multi-course meal was assembled in aluminum packaging in a food factory and flash frozen , then reheated at home in a thermal oven to be served while watching TV .


Mid-twentieth century foods also added novelty packaging elements like spray cheese in an aerosol can , pimento stuffed olives , and drink pouches .


Microwave popcorn is an example of such a product .


Activists have raised concerns about the wholesomeness , safety , or humaneness of these innovations and recommend alternatives such as organic produce , veganism / vegetarianism , and locavore diets .


Excluding Alaska and Hawaii , the terrain spans from east to west and more than from north to south .


It includes the six states of Connecticut , Maine , Massachusetts , New Hampshire , Rhode Island , and Vermont , with its largest city and cultural capital Boston , founded in 1630 .


Most of the cuisine started with one-pot cookery , which resulted in such dishes as succotash , chowder , baked beans , and others .


Typical condiments include maple syrup , grown from the native sugar maple , molasses , and cranberry sauce .


Meat is present though not as prominent , and typically is either stewed in dishes like Yankee pot roast and New England boiled dinner or braised , as in a picnic ham ; these dishes suit the weather better as summers are humid and hot but winters are raw and cold , getting below 0 " °C for most of the winter and only just above it by March .


Large quahogs are stuffed with breadcrumbs and seasoning and baked in their shells , and smaller ones often find their way into clam chowder .


Other preparations include clams casino , clams on the half shell served stuffed with herbs like oregano and streaky bacon .


Like its neighbor Philadelphia , many rare and unusual liquors and liqueurs often find their way into a mixologist 's cupboard or restaurant wine list .


Whitefish salad , lox , and matzoh ball soup are now standard fare made to order at local diners and delicatessens , but started their life as foods that made up a strict dietary code .


Like other groups before them , many of their dishes passed into the mainstream enough so that they became part of diner fare by the end of the 20th century , a type of restaurant that is now more numerous in this region than any other and formerly the subject matter of artist Edward Hopper .


Today alongside the pierogi , the sausage is served on a long roll with mustard like a hot dog or as a Maxwell Street Polish , a sandwich that has caramelized onions as an essential ingredient .


Next to the hotdish at the potlucks usually is where the glorified rice is found : this is a dish made of a kind of rice pudding mixed with crushed pineapple and maraschino cherries .


Dessert is usually something like gooey butter cake , invented in the city in the 1930 s .


Peaches have been grown in this region since the 17th century and are a staple crop as well as a favorite fruit , with peach cobbler being a signature dessert .


Accompanying many meals is the southern style fluffy biscuit , where the leavening agent is baking soda and often includes buttermilk , and for breakfast they often accompany country ham , grits , and scrambled eggs .


Gumbos tend to be thickened with okra , or the leaves of the sassafrass tree .


One of the core favorite foodstuffs is Pacific salmon , native to many of the larger rivers of the area and often smoked or grilled on cedar planks .


In Alaska , wild game like ptarmigan and moose meat feature extensively since much of the state is wilderness .


Favorite grains are mainly wheat , and the region is known for sourdough bread .


Indeed , even national fast food chains operating in the state , such as McDonald 's , offer locally grown chile on many of their menu items .


Tortillas are still made the traditional way in this area and form an important component of the spicy breakfast burrito , which contains ham , eggs , and salsa or pico de gallo .


Nowhere is this fiery mix of spice more evident than in the dishes chili con carne , a meaty stew , and cowboy beans , both of which are a feature of regional cookoffs .


A typical accompaniment or appetizer of all these states is the tortilla chip , which sometimes includes cornmeal from cultivars of corn that are blue or red in addition to the standard yellow of sweetcorn , and is served with salsa of varying hotness .


California-style pizza tends to have disparate ingredients with an emphasis on vegetables , with any combination of chili oil , prawns , eggs , chicken , shiitake mushrooms , olives , bell pepper , goat cheese , and feta cheese .


Only during the 1970 s and 1980 s did television chefs such as James Beard and Jeff Smith shift the focus towards home-grown cooking styles , particularly those of the different ethnic groups within the nation .


During his reign , the authoritarian nature of his rule put him at sharp odds with the Senate , whose powers he drastically curtailed .


His 15-year reign was the longest since that of Tiberius .


He was succeeded the same day by his advisor Nerva .


To aid the advance , a large legionary fortress was constructed at Inchtuthil .


The most common explanation is that steel is named after Damascus , the capital city of Syria and one of the largest cities in the ancient Levant .


In August 1986 , he captured Farkhar in Takhar Province .


The " brown bear " ( " Ursus arctos " ) is a large bear species found across Eurasia and North America .


It is one of the largest living terrestrial members of the order Carnivora , rivaled in size only by its closest relative , the polar bear ( " Ursus maritimus " ) , which is much less variable in size and slightly bigger on average .


, this and the American black bear are the only bear species not classified as threatened by the IUCN .


A genetic analysis indicated that the brown bear lineage diverged from the cave bear species complex approximately 1.2 – 1.4 " million years ago , but did not clarify if " U. savini " persisted as a paraspecies for the brown bear before perishing .


Brown bear fossils discovered in Ontario , Ohio , Kentucky and Labrador show that the species occurred farther east than indicated in historic records .


The history of the bears of the Alexander Archipelago is unusual in that these island populations carry polar bear DNA , presumably originating from a population of polar bears that was left behind at the end of the Pleistocene , but have since been connected with adjacent mainland populations through movement of males , to the point where their nuclear genomes are now more than 90 % of brown bear ancestry .


The smallest brown bears , females during spring among barren-ground populations , can weigh so little as to roughly match the body mass of males of the smallest living bear species , the sun bear ( " Helarctos malayanus " ) , while the largest coastal populations attain sizes broadly similar to those of the largest living bear species , the polar bear .


Apart from the cinnamon subspecies of the American black bear ( " U. americanus cinnamonum " ) , the brown bear is the only modern bear species to typically appear truly brown .


Another extant ursine bear , the sloth bear ( " Melursus ursinus " ) , has a proportionately longer skull than the brown bear and can match the skull length of even large brown bear subtypes , presumably as an aid for foraging heavily on insect colonies for which a long muzzle is helpful as an evolved feature in several unrelated mammalian groups .


Their rarity in this area has led biologists to release bears , mostly female , from Slovenia in spring 2006 to reduce the imbalance and preserve the species ' presence in the area .


In Arctic areas , the potential habitat of the brown bear is increasing .


The warming of that region has allowed the species to move farther north into what was once exclusively the domain of the polar bear .


The Syrian brown bear ( " Ursus arctos syriacus " ) is very rare and it has been extirpated from more than half of its historic range .


This species is mostly solitary , although bears may gather in large numbers at major food sources ( e.g. , open garbage dumps or rivers holding spawning salmon ) and form social hierarchies based on age and size .


Similarly , in British Columbia , bears of the two sexes travel relatively compact home ranges of and .


In Yellowstone National Park , home ranges for females are up to and up to for males .


In Romania , the largest home range was recorded for adult males ( 3,143 " km , 1214 sq mi ) .


Wild females have been observed reproducing up to 28 years of age , which is the oldest known age for reproduction of any ursid in the wild .


Brown bears usually avoid areas where extensive development or urbanization has occurred , unlike the smaller , more inoffensive American black bear which can adapt to peri-urban regions .


In other areas , such as Alaska , dumps may continue to be an attractant for brown bears .


The saying " A fed bear is a dead bear " has come into use to popularize the idea that allowing a bear to scavenge human garbage , such as trash cans and campers ' backpacks , pet food , or other food sources that draw the bear into contact with humans , can result in the bear 's death .


In Scandinavia , there are only four known cases since 1902 of bear encounters which have resulted in death .


The grizzly bear is the state animal of Montana .


For example , during the 2008 flooding , Credit Island in the city 's southwest corner remained closed for 5 ½ months while crews worked on cleaning up damage and removing river debris .


NorthPark Mall is the city 's main shopping mall and has 160 stores .


Plans are being discussed to connect the two trails in Riverdale .


This mariner , of course , was Christopher Columbus .


It is often served with cold meat from the Sunday roast and pickles or brown sauce , or as an accompaniment to a full English breakfast .


However , its next recorded use was in its present sense , by Robert Southey in 1809 .


The University of Massachusetts Amherst gained a chapter in 1970 .


" ) ] " on Woodward and Bernstein by getting a first hand story " , and expressed the wish that he be transferred elsewhere .


He violated his parole by visiting India for religious study in 1987 – 1988 , which led to his final prison term , in federal prison , in 1990 .


He was the eldest son of Theodosius I and his first wife Aelia Flaccilla , and brother of Honorius .


A weak ruler , his reign was dominated by a series of powerful ministers and by his wife , Aelia Eudoxia .


He brought to trial two prominent military officers , Timasius and Abundantius .


Therefore , equatorial coordinates ( including declination ) are inherently relative to the year of their observation , and astronomers specify them with reference to a particular year , known as an epoch .


0 , which is January 1 , 2000 at 12:00 TT .


A star 's direction remains nearly fixed due to its vast distance , but its right ascension and declination do change gradually due to precession of the equinoxes and proper motion , and cyclically due to annual parallax .


Likewise , near the local winter solstice , the Sun remains below the horizon all day , which is called polar night .


The resulting album , " The " Chirping " Crickets " , was released on November 27 , 1957 .


" , with " Not Fade Away " on the B-side .


He wanted to make an album with Ray Charles and Mahalia Jackson .


More recently , it has been applied to emigrant groups that continue their involvement in their homeland from overseas , such as the category of long-distance nationalists identified by Benedict Anderson .


Much of Siberia 's population has its origins in internal migration – voluntary or otherwise – from European Russia since the 16th century .


In Africa , a new series of diasporas formed following the end of colonial rule .


In Latin America , following the 1959 Cuban Revolution and the introduction of communism , over a million people have left Cuba .


Thousands of refugees from deteriorating conditions in Zimbabwe have gone to South Africa .


The long war in Congo , in which numerous nations have been involved , has also spawned millions of refugees .


Most beer is fermented with a brewer 's yeast and flavoured with hops .


Grain is malted by soaking it in water , allowing it to begin germination , and then drying the partially germinated grain in a kiln .


This is because of its fibrous husk , which is important not only in the sparging stage of brewing ( in which water is washed over the mashed barley grains to form the wort ) but also as a rich source of amylase , a digestive enzyme that facilitates conversion of starch into sugars .


Other malted and unmalted grains ( including wheat , rice , oats , and rye , and , less frequently , maize ( corn ) and sorghum ) may be used .


In recent years , a few brewers have produced gluten-free beer made with sorghum with no barley malt for people who cannot digest gluten-containing grains like wheat , barley , and rye .


Hops are the female flower clusters or seed cones of the hop vine " Humulus lupulus " , which are used as a flavouring and preservative agent in nearly all beer made today .


Before the thirteenth century , beer was flavoured with plants such as yarrow , wild rosemary , and bog myrtle , and other ingredients such as juniper berries , aniseed and ginger , which would be combined into a mixture known as gruit and used as hops are now used ; between the thirteenth and the sixteenth century , during which hops took over as the dominant flavouring , beer flavoured with gruit was known as ale , while beer flavoured with hops was known as beer .


The wort is moved into a large tank known as a " copper " or kettle where it is boiled with hops and sometimes other ingredients such as herbs or sugars .


Mashing is a form of steeping , and defines the act of brewing , such as with making tea , sake , and soy sauce .


Technically , wine , cider and mead are not brewed but rather vinified , as there is no steeping process involving solids .


After mashing , the beer wort is boiled with hops ( and other flavourings if used ) in a large tank known as a " copper " or brew kettle – though historically the mash vessel was used and is still in some small breweries .


A hopback is a traditional additional chamber that acts as a sieve or filter by using whole hops to clear debris ( or " trub " ) from the unfermented ( or " green " ) wort , as the whirlpool does , and also to increase hop aroma in the finished beer .


It is during this stage that sugars won from the malt are converted into alcohol and carbon dioxide , and the product can be called beer for the first time .


Generally , warm-fermented beers , which are usually termed ale , are ready to drink within three weeks after the beginning of fermentation , although some brewers will condition or mature them for several months .


When a beer has been brewed using a cool fermentation of around , compared to typical warm fermentation temperatures of , then stored ( or lagered ) for typically several weeks ( or months ) at temperatures close to freezing point , it is termed a " lager " .


Kräusening is a conditioning method in which fermenting wort is added to the finished beer .


Brewing by-products are " spent grain " and the sediment ( or " dregs " ) from the filtration process which may be dried and resold as " brewers dried yeast " for poultry feed , or made into yeast extract which is used in brands such as Vegemite and Marmite .


In 1903 , he received his BA degree in mathematics at Cambridge , converted by payment to MA in 1907 .


Alexander Melville Bell ( 1867 ) devised an ingenious iconic phonetic alphabet which included an elaborate system for vowels .


He died at his home in Gerrards Cross on 4 December 1967 .


Nobel laureate Robert Burns Woodward described a parameter " h " as a measure of the height of the trigonal pyramid defined by the nitrogen ( as the apex ) and its three adjacent atoms .


, from the Atlantic Ocean in the west to the Arabian Sea in the east , and from the Mediterranean Sea in the north to the Horn of Africa and the Indian Ocean in the southeast .


Arabs arrived in the Palmyra in the late first millennium BCE .


They mainly settled in the Hauran region and spread to modern Lebanon , Palestine and Jordan .


They established garrison towns at Ramla , Raqqa , Basra , Kufa , Mosul and Samarra , all of which developed into major cities .


In the Netherlands 180,000 , and in Denmark 121,000 .


The first was a neo-classical movement which sought to rediscover the literary traditions of the past , and was influenced by traditional literary genres - such as the " maqama " - and works like " One Thousand and One Nights " .


The religious beliefs and practices of the nomadic bedouin were distinct from those of the settled tribes of towns such as Mecca .


Nomadic religious belief systems and practices are believed to have included fetishism , totemism and veneration of the dead but were connected principally with immediate concerns and problems and did not consider larger philosophical questions such as the afterlife .


This includes traditional star names such as Aldebaran , scientific terms like " alchemy " ( whence also " chemistry " ) , " algebra " , " algorithm " , " alcohol " , " alkali " , " cipher " , " zenith " , etc .


In Egypt , around 40 % of the population marry a cousin .


A 1992 survey in Jordan found that 32 % were married to a first cousin ; a further 17.3 % were married to more distant relatives .


The general idea of natural equations for obtaining curves from local curvature appears to have been first considered by Leonhard Euler in 1736 , and many examples with fairly simple behavior were studied in the 1800 s .


Starting with the work of Riemann , the " intrinsic " point of view was developed , in which one cannot speak of moving " outside " the geometric object because it is considered to be given in a free-standing way .


One jumper drowned in the Merced River while evading arresting park rangers , having declared " No way are they gonna get me .


The term was coined in 1969 by architect Paolo Soleri , who believed that a completed arcology would provide space for a variety of residential , commercial , and agricultural facilities while minimizing individual human environmental impact .


More recently authors such as Peter Hamilton in " Neutronium Alchemist " and Paolo Bacigalupi in " The Water Knife " explicitly used arcologies as part of their scenarios .


The " dhole " ( ; " Cuon alpinus " ) is a canid native to Central , South , East Asia , and Southeast Asia .


During the Pleistocene , the dhole ranged throughout Asia , Europe , and North America but became restricted to its historical range 12,000 – 18,000 " years ago .


The dhole is a highly social animal , living in large clans without rigid dominance hierarchies In tropical forests , the dhole competes with tiger and leopard , targeting somewhat different prey species , but still with substantial dietary overlap .


In appearance , the dhole has been variously described as combining the physical characteristics of the gray wolf and the red fox , The rostrum is shorter than that of domestic dogs and most other canids .


Its ears are somewhat rounded , but less so than the African wild dog .


The dhole still occurs in Tibet and possibly also in North Korea .


It once inhabited the alpine steppes extending into Kashmir to the Ladakh area , but has not been recorded in Pakistan .


One pack was sighted in the Qilian Mountains in 2006 .


It is also present in Arunachal Pradesh , Assam , Meghalaya , and West Bengal and in the Indo-Gangetic Plain 's Terai region .


Its presence was confirmed in the Kanchenjunga Conservation Area in 2011 by camera traps .


In February 2020 , dholes were sighted in the Vansda National Park , with camera traps confirming the presence of two individuals in May of the same year .


This was the first confirmed sighting of dholes in Gujarat since 1970 .


In Bhutan , the dhole is present in Jigme Dorji National Park .


In Bangladesh , it inhabits forest reserves in the Sylhet area , as well the Chittagong Hill Tracts in the southeast .


A disjunct dhole population was reported in the area of Trabzon and Rize in northeastern Turkey near the border with Georgia in the 1990 s .


In Thailand , clans rarely exceed three individuals .


Once weaning begins , the adults of the clan will regurgitate food for the pups until they are old enough to join in hunting .


They may suffer from rabies , canine distemper , mange , trypanosomiasis , canine parvovirus and endoparasites such as cestodes and roundworms .


Three dhole-like animals are featured on the coping stone of the Bharhut stupa dating from 100 BC .


It was also quickly determined that Mohamed Atta was the pilot among the hijackers .


This motion is named after the botanist Robert Brown , who first described the phenomenon in 1827 , while looking through a microscope at pollen of the plant " Clarkia pulchella " immersed in water .


In 1905 , almost eighty years later , theoretical physicist Albert Einstein published a paper where he modeled the motion of the pollen as being moved by individual water molecules , making one of his first major scientific contributions .


He attended Princeton University on academic and NROTC partial scholarships .


In 1959 , he moved on to become a staff assistant to Congressman Robert P. Griffin of Michigan .


While paying a visit to Columbia University , he met Isidor Isaac Rabi , who sparked in him an interest in recent discoveries related to the hyperfine structure of deuterium .


It is a militarised atoll just south of the equator in the central Indian Ocean , and the largest of 60 small islands comprising the Chagos Archipelago .


The atoll is located east of Tanzania 's coast , south-southwest of the southern tip of India ( at Kanyakumari ) , and west-northwest of the west coast of Australia ( at Cape Range National Park , Western Australia ) .


The Sebastian Cabot map ( Antwerp 1544 ) shows a number of islands to the south which may be the Mascarene Islands .


The island is a haven for several types of crustacean ; " warrior crabs " ( " Cardisoma carnifex " ) overrun the jungle at night .


The extremely large coconut crab or robber crab ( " Birgus latro " ) is found here in large numbers .


The house gecko ( " Hemidactylus frenatus " ) , the mourning gecko ( " Lepidodactylus lugubris " ) , the garden lizard ( an agamid ) ( " Calotes versicolor " ) , and the cane toad ( " Bufo marinus " ) .


This equipment was used during the Persian Gulf War , when the squadron transported equipment to Saudi Arabia .


This indicated that , for all their powers , they could not perform the Eucharist , and were in this respect outranked by every priest , reinforcing the prestige of the clergy .


However , this name refers only to FC Barcelona , the football club .


The first attributes the founding of the city to the mythological Hercules .


Pomponius Mela mentions it among the small towns of the district , probably as it was eclipsed by its neighbour " Tarraco " ( modern Tarragona ) , but it may be gathered from later writers that it gradually grew in wealth and consequence , favoured as it was with a beautiful situation and an excellent harbour .


The city minted its own coins ; some from the era of Galba survive .


The great plague of 1650 – 1654 halved the city 's population .


In the 18th century , a fortress was built at Montjuïc that overlooked the harbour .


For the year 2008 the city council calculated the population to 1,621,090 living in the 102.2 " km sized municipality , giving the city an average population density of 15,926 inhabitants per square kilometre with Eixample being the most populated district .


Half of the municipality or 50.2 " km , all of it located on the municipal edge is made up of the ten least densely populated neighbourhoods containing less than 10 % of the city 's population , the uninhabited Zona Franca industrial area and Montjuïc forest park .


It performs around 75 concerts per season and its current director is Eiji Oue .


The major thoroughfare of La Rambla is home to mime artists and street performers .


Peter Gelderloos estimates that there around 200 squatted buildings and 40 social centres across the city with thousands of inhabitants , making it one of the largest squatter movements in the world .


The famous boulevard of La Rambla , whilst no longer an important vehicular route , remains an important pedestrian route .


Especially remarkable is the work of architect Antoni Gaudí , which can be seen throughout the city .


The band has been through numerous lineup changes over the years ; vocalist Shagrath and rhythm guitarist Silenoz are the only original members who still remain , with lead guitarist Galder being a longstanding member .


He was then subsequently fired and replaced by Kimberly Goss for their 1997 / 1998 world tour .


They are found at elevations up to above sea level and have been seen on sea ice close to the North Pole .


It came to the isolated North Atlantic island at the end of the last ice age , walking over the frozen sea .


The young fox crossed the polar ice from Norway to Greenland in 21 days , a distance of .


She then moved on to Ellesmere Island in northern Canada , covering a total recorded distance of in 76 days , before her GPS tracker stopped working .


The IUCN has assessed it as being of " least concern " .


An alternative explanation of the red fox 's gains involves the gray wolf .


Its roots went earlier , and performers like Burl Ives , Woody Guthrie , Lead Belly , and Oscar Brand had enjoyed a limited general popularity in the 1930 s and 1940 s .


President Nursultan Nazarbayev attended the final .


Attending the meeting were also Minister of Sport , Tourism and Youth policy Vitaly Mutko and presidential adviser Igor Levitin .


After the release of the expansion , multimedia producer Michael Ely wrote a trilogy of novels based on the game .


They are found primarily in Syria , Lebanon and Israel , with small communities in Jordan .


According to most sources , he was born in Bukhara .


These concepts superseded all ritual , law and dogma and requirements for pilgrimage , fasting , holy days , prayer , charity , devotion , creed and particular worship of any prophet or person was downplayed .


For example , Muhammad is considered a " natiq " , Ali is considered an " asas " , but both are considered prophets .


They are found in Syria , Lebanon and Israel .


The community does celebrate Eid al-Adha , however , considered their most significant holiday .


This haplogroup originates from prehistoric South Asia and has spread from Pakistan into southern Iran .


In 2001 , A. L. Kennedy , who was a judge in 1996 , called the prize " a pile of crooked nonsense " with the winner determined by " who knows who , who 's sleeping with who , who 's selling drugs to who , who 's married to who , whose turn it is " .


Some commentators , such as John Calvin , attach no great importance to the precise dating .


According to the National Safety Council in the United States , 300,000 injuries are caused by doors every year .


Chapter 13 foretells the destruction of the kingdom at the hands of Assyria , because there has been no repentance .


It was first proposed by Edgar F. Codd as part of his relational model .


An influential commander named Abu Sabaya was killed at sea in June 2002 while trying to evade local forces .


The group was reported to have trained alongside Jemaah Islamiyah militants .


The plot was reported to have involved detonating a car bomb in Cebu City where the summit was to take place .


On 6 November , he was freed near Zamboanga City after payment of P1 .


The kidnappings were criticised by Indonesia .


Set in the reign of Jeroboam II ( 786 – 746 " BC ) , it was probably written in the post-exilic period , some time between the late 5th to early 4th century BC .


There are two standardized modern literary forms , Eastern Armenian and Western Armenian , with which most contemporary dialects are mutually intelligible .


After World War I , the existence of the two modern versions of the same language was sanctioned even more clearly .


The building houses five restaurants , both independently owned and international franchises such as Tim Hortons .


John Forrest was the longest-serving president , holding the office from 1885 to 1911 .


The school is working to build a new arena jointly with nearby Saint Mary 's University , whose facility is also aging .


Eight graduates have served as Lieutenant Governors : John Crosbie , Myra Freeman , Clarence Gosse , John Keiller MacKay , Henry Poole MacKeen , Fabian O'Dea , and Albert Walsh .


Twelve graduates have served as provincial premiers : Allan Blakeney , John Buchanan , Alex Campbell , Amor De Cosmos , Darrell Dexter , Joe Ghiz , John Hamm , Angus Lewis Macdonald , Russell MacLellan , Gerald Regan , Robert Stanfield , Clyde Wells , and Danny Williams .


Ashurbanipal was at the height of his glory .


It is the principal sound generation technique used by Eminent organs .


Also the composite sinusoidal modeling ( CSM ) used on a singing speech synthesis feature on Yamaha CX5M ( 1984 ) , is known to use a similar approach which was independently developed during 1966&ndash ; 1979 .


The computers sold well initially and attracted the interest of independent software developers including Microdeal .


In the sixth dispute , the people of Israel illustrate the extent of their disillusionment .


Of the three chapters in the book , the first two are a dialog between Yahweh and the prophet .


During World War II , these ships would become known as fleet carriers .


The Royal Australian Navy operates two s .


In May 2019 , the Center for Strategic and International Studies released satellite images of what they said was the third carrier under construction at Jiangnan Shipyard near Shanghai .


The carrier is being constructed by Cochin Shipyard .


Primary evidence for dark matter comes from calculations showing that many galaxies would fly apart , or that they would not have formed or would not move as they do , if they did not contain a large amount of unseen matter .


Fellow Dutchman and radio astronomy pioneer Jan Oort also hypothesized the existence of dark matter in 1932 .


One of the consequences of general relativity is massive objects ( such as a cluster of galaxies ) lying between a more distant source ( such as a quasar ) and an observer should act as a lens to bend the light from this source .


WIMPs coming from the direction in which the Sun travels ( approximately towards Cygnus ) may then be separated from background , which should be isotropic .


The older taxon Sporozoa , included in Protozoa , was created by Leuckart in 1879 and adopted by Bütschli in 1880 .


" Dermocystidium " was also thought to be sporozoan .


While TMV is capable of infecting many plant families these are primarily herbaceous dicots .


Fernet is most commonly enjoyed as a mixed drink with Coca-Cola .


It is important to local commercial fisheries and is also popular as a game fish .


The company has a licensing agreement with Tumi Inc. , launching a collection of eight co-branded luggage pieces in 2006 , sold through both of the brands ' retail outlets .


Canadian philosopher Christopher Tindale approaches somewhat different the " tu quoque " fallacy .


The philosopher Charles Taylor has argued that " ad hominem " reasoning ( discussing facts about the speaker or author relative to the value of his statements ) is essential to understanding certain moral issues due to the connection between individual persons and morality ( or moral claims ) , and contrasts this sort of reasoning with the apodictic reasoning ( involving facts beyond dispute or clearly established ) of philosophical naturalism .


The term " analysis of algorithms " was coined by Donald Knuth .


During the civil war and the ensuing Soviet–Afghan War , most of the country 's infrastructure was destroyed .


This concept shipped as the Data General Eclipse series , which offered the ability to add additional circuity to tailor the instruction set for scientific or data processing workloads .


Its external design has been reported to be the direct inspiration for the front panel of the MITS Altair ( 1975 ) microcomputer .


Mid-way into their effort the home computer revolution took off , leading to the addition of a keyboard and features to produce the Atari 800 and its smaller sibling , the 400 .


Additional hotels were also planned in Las Vegas , Denver , Chicago , Austin , Seattle , San Francisco , and San Jose .


The second strike was resolved after the province 's labour minister , Mark Parent , appointed a mediator , on 1 November , to facilitate an agreement .


A common non-traditional wood gaining popularity is sapele , which is tonally similar to mahogany but slightly lighter in color and possessing a deep grain structure that is visually appealing .


From the 1960 s through the 1980 s , " by far the most significant developments in the design and construction of acoustic guitars " were made by the Ovation Guitar Company .


Steel-string guitars are also important in the world of flatpicking , as utilized by such artists as Clarence White , Tony Rice , Bryan Sutton , Doc Watson and David Grier .


In January 1831 , he began publication of the " Millennial Harbinger " .


After the American Civil War , the schism grew .


The process that led to the separation had begun prior to the American Civil War .


It shares in the dialog and in the theological endeavors of the World Council of Churches .


Her presidency followed the presidency of Sharon E. Watkins , the first woman to lead a mainline denomination as their chief executive .


It works closely with Church World Service and church related organizations in countries around the world where disasters strike , providing emergency aid .


The movement established similar schools , especially in the years following the American Civil War .


Martin V was elected as new pope in 1417 .


This type of experiment was first performed , using light , by Thomas Young in 1801 , as a demonstration of the wave behavior of light .


Because it demonstrates the fundamental limitation of the ability of the observer to predict experimental results , Richard Feynman called it " a phenomenon which is impossible [ … ] to explain in any classical way , and which has in it the heart of quantum mechanics .


In 2012 , researchers at the University of Nebraska–Lincoln performed the double-slit experiment with electrons as described by Richard Feynman , using new instruments that allowed control of the transmission of the two slits and the monitoring of single-electron detection events .


According to the relational interpretation of quantum mechanics , first proposed by Carlo Rovelli , observations such as those in the double-slit experiment result specifically from the interaction between the observer ( measuring device ) and the object being observed ( physically interacted with ) , not any absolute property possessed by the object .


Buddhapālita ( 470 – 550 ) has been understood as the originator of the ' prāsaṅgika ' approach which is based on critiquing essentialism only through " reductio ad absurdum " arguments .


For Śāntarakṣita , Kamalaśīla and their defenders , reason is useful in establishing arguments that lead one to a correct understanding of emptiness , then , through the use of meditation , one can reach non-conceptual gnosis that does not rely on reason .


Franz Liszt , Franz Schubert , Ludwig van Beethoven , Johann Nepomuk Hummel and Franz Xaver Wolfgang Mozart were among the most famous of his pupils .


This was a pattern imitated by later composers , most famously and successfully by Wolfgang Amadeus Mozart in " Don Giovanni " .


A good high school baseball player , he tried out for the Kansas City Royals , but was released after an injury .


He has since said that he follows a vegan diet and is " extremely healthy " , eating no junk food as he is allergic to wheat and dairy .


He is also a professed fan of the Indianapolis Colts football team .


This avoided some difficult construction of bridges over the rivers of southern Connecticut .


The track is an homage to the music of Gerry Anderson 's " UFO " , composed by Barry Gray .


He also spoke of how he first came up with designs for the robots first as if they were making designs to appeal to toy companies , rather than how " Gundam " was created with a toy company wanting an anime to represent their new product .


The drama CD was written by series head writer Chiaki J. Konaka and featured the series ' voice cast .


It originated in Europe , where it is the universal standard , replacing earlier cordless phone standards , such as 900 " MHz CT1 and CT2 .


The DECT standard was developed by ETSI in several phases , the first of which took place between 1988 and 1992 when the first round of standards were published .


The original DECT frequency band ( 1880 – 1900 " MHz ) is used in all countries in Europe .


Opioid tolerance should not be confused with opioid-induced hyperalgesia .


Another example of this is in phytoplankton and zooplankton .


Some BIOSes contain a software licensing description table ( SLIC ) , a digital signature placed inside the BIOS by the original equipment manufacturer ( OEM ) , for example Dell .


AMD provided product specifications for some chipsets , and Google is sponsoring the project .


This state was first predicted , generally , in 1924 – 1925 by Albert Einstein following and crediting a pioneering paper by Satyendra Nath Bose on the new field now known as quantum statistics .


About four months later , an independent effort led by Wolfgang Ketterle at MIT condensed sodium-23 .


In 1970 , BECs were proposed by Emmanuel David Tannenbaum for anti-stealth technology .


In 2014 a potential dibaryon was detected at the Jülich Research Center at about 2380 MeV .


The law is used widely in infra-red spectroscopy and near-infrared spectroscopy for analysis of polymer degradation and oxidation ( also in biological tissue ) as well as to measure the concentration of various compounds in different food samples .


According to historian Justo L. González , apostolic succession is generally understood today as meaning a series of bishops , regardless of see , each consecrated by other bishops , themselves consecrated similarly in a succession going back to the apostles .


Cyprian also asserts that " if any one is not with the bishop , he is not in the church " ( " Ep. " 66.9 ) .


First , the ordination rite of Edward VI had removed language of a sacrificial priesthood .


The Anglican Communion " has never officially endorsed any one particular theory of the origin of the historic episcopate , its exact relation to the apostolate , and the sense in which it should be thought of as God given , and in fact tolerates a wide variety of views on these points " .


Eventually these were restored to the prophet Joseph Smith and various others in a series of divine conferrals and ordinations by angelic men who had held this authority during their lifetimes ( see this partial list of restoration events ) .


Among the first who rejected the doctrine of apostolic succession were John Calvin , and Martin Luther .


By the end of the 19th century , it had formed four governments under William Gladstone .


William Ewart Gladstone served as prime minister four times ( 1868 – 74 , 1880 – 85 , 1886 , and 1892 – 94 ) .


The cost was high , however , as the government was required by the king to call two general elections in 1910 to validate its position and ended up frittering away most of its large majority , being left once again dependent on the Irish Nationalists .


The country seemed to be on the brink of civil war when the First World War broke out in August 1914 .


He resigned as prime minister and was succeeded by Bonar Law .


The isomer is the one most often encountered : it occurs naturally in many foods , and is one form ( " vitamer " ) of vitamin C , an essential nutrient for humans and many animals .


It is used as a food additive and a dietary supplement for its antioxidant properties .


The ascorbate anion forms salts , such as sodium ascorbate , calcium ascorbate , and potassium ascorbate .


Another major use of - ascorbic acid is as dietary supplement .


Natural biosynthesis of vitamin C occurs in many plants , and animals , by a variety of processes .


The city became the 4th - largest in the nation in 1920 , after only New York City , Chicago and Philadelphia with the influence of the booming auto industry .


In November 1973 , the city elected Coleman Young as its first black mayor .


The Renaissance Center , a mixed-use office and retail complex , opened in 1977 .


In September 2008 , Mayor Kwame Kilpatrick ( who had served for six years ) resigned following felony convictions .


The state governor declared a financial emergency in March 2013 , appointing Kevyn Orr as emergency manager .


Together with the Renaissance Center , these buildings form a distinctive and recognizable skyline .


The oldest extant neighborhoods include West Canfield and Brush Park .


In 2011 , Mayor Dave Bing announced a plan to categorize neighborhoods by their needs and prioritize the most needed services for those neighborhoods .


Compuware completed its world headquarters in downtown in 2003 .


This dynamic is luring additional new residents , and former residents returning from other cities , to the city 's Downtown along with the revitalized Midtown and New Center areas .


Many of the area 's prominent museums are in the historic cultural center neighborhood around Wayne State University and the College for Creative Studies .


Joe Louis won the heavyweight championship of the world in 1937 .


Crime has since decreased and , in 2014 , the murder rate was 43.4 per 100,000 , lower than in St. Louis .


In 1973 , the city elected its first black mayor , Coleman Young .


The University of Detroit Mercy School of Law is Downtown across from the Renaissance Center .


The plan of 1691 , which had been proposed by William Paterson three years before , had not then been acted upon .


The first governor was Sir John Houblon , who is depicted in the £ 50 note issued in 1994 .


There are nine notes left in circulation ; one is housed at Tone Dale House , Wellington .


As of 2012 , the current director for financial stability is Andy Haldane .


Designers such as Elsa Schiaparelli used it for jewelry and also for specially designed dress buttons .


Bakelite was also used to make presentation boxes for Breitling watches .


The club is one of the five teams that has earned the right to keep the European Cup and to wear a multiple-winner badge ; they won consecutively in 1971 – 1973 .


Spanish midfielder Roger was the last player to wear the number .


As the bean pods mature , they turn yellow and dry up , and the beans inside change from green to their mature colour .


Phytic acid and phytates , present in grains , nuts , seeds and beans , interfere with bone growth and interrupt vitamin D metabolism .


Pioneering work on the effect of phytic acid was done by Edward Mellanby from 1939 .


After receiving his M.A. in 1905 , he began research on thermionic emission in the Cavendish Laboratory .


James Jeans contributed the important suggestion that stellar matter would certainly be ionized , but that was the end of any collaboration between the pair , who became famous for their lively debates .


At the front of the chest , the " breast tissue " can extend from the clavicle ( collarbone ) to the middle of the sternum ( breastbone ) .


The lymphatic drainage of the breasts is especially relevant to oncology because breast cancer is common to the mammary gland , and cancer cells can metastasize ( break away ) from a tumour and be dispersed to other parts of the body by means of the lymphatic system .


While it has been a common belief that breastfeeding causes breasts to sag , researchers have found that a woman 's breasts sag due to four key factors : cigarette smoking , number of pregnancies , gravity , and weight loss or gain .


The morphological structure of the human breast is identical in males and females until puberty .


Medical conditions can cause overdevelopment ( e.g. , virginal breast hypertrophy , macromastia ) or underdevelopment ( e.g. , tuberous breast deformity , micromastia ) in girls and women .


By mid-pregnancy , the breast is physiologically capable of lactation and some women can express colostrum , a form of breast milk .


In boys and men , abnormal breast development is manifested as gynecomastia , the consequence of a biochemical imbalance between the normal levels of estrogen and testosterone in the male body .


There were exceptions : Aphrodite , the goddess of love , was more frequently portrayed fully nude , though in postures that were intended to portray shyness or modesty , a portrayal that has been compared to modern pin ups by historian Marilyn Yalom .


Leonard Matlovich appeared on the cover of " Time " in 1975 .


Other lawsuits fighting discharges highlighted the service record of service members like Tracy Thorne and Margarethe ( Grethe ) Cammermeyer .


Plaintiffs introduced statements by President Barack Obama , from prepared remarks , that DADT " does n't contribute to our national security " , " weakens our national security " , and that reversal is " essential for our national security " .


The Center for American Progress issued a report in March 2010 that said a smooth implementation of an end to DADT required eight specified changes to the military 's internal regulations .


Representative Duncan D. Hunter announced plans in January 2011 to introduce a bill designed to delay the end of DADT .


Senior Airman Randy Phillips , after conducting a social media campaign seeking encouragement coming out and already out to his military co-workers , came out to his father on the evening of September 19 .


Retired Rear Adm. Alan M. Steinman became the highest-ranking person to come out immediately following the end of DADT .


Fortune-telling and other forms of divination were widespread through the Middle Ages .


In 813 , after the death of caliph Al-Amin , the palace was no longer used as the home for the caliph and his family .


Another was established by Sabur ibn Ardashir in 991 or 993 for the literary men and scholars who frequented his academy .


However , the Iran–Iraq War of the 1980 s was a difficult time for the city , as money was diverted by Saddam Hussein to the army and thousands of residents were killed .


The community has been subject to kidnappings , death threats , vandalism , and house burnings by Al-Qaeda and other insurgent groups .


The zoological park used to be the largest in the Middle East .


The city is located on a vast plain bisected by the Tigris river .


The " E. coli " DNA ligase is encoded by the " lig " gene .


DNA ligase in " E. coli " , as well as most prokaryotes , uses energy gained by cleaving nicotinamide adenine dinucleotide ( NAD ) to create the phosphodiester bond .


It can also ligate blunt-ended DNA with much greater efficiency than " E. coli " DNA ligase .


Designed with help from Gioacchino Colombo , the car failed to perform to expectations and the company 's attempts at automobile production were halted .


OCLC , a non-profit cooperative that serves libraries , currently maintains the system and licenses online access to " WebDewey " , a continuously updated version for catalogers .


It is not known who received copies or how many commented as only one copy with comments has survived , that of Ernest Cushing Richardson .


The 15th edition , edited by Milton Ferguson , implemented the growing concept of the " standard edition " , designed for the majority of general libraries but not attempting to satisfy the needs of the very largest or of special libraries .


She was followed by Dorcas Fellows , who was editor until her death in 1938 .


Since World War II , gun-armed tank destroyers have fallen out of favor as armies have favored multirole main battle tanks .


During World War II , most armored cars were engineered for reconnaissance and passive observation , while others were devoted to communications tasks .


In the 1930 s , a new sub-class of armored car emerged in the United States , known as the " scout car " .


This system was widely copied in various NATO forces .


Subsequent to the pandemic " the " furste moreyn " " ( first murrain ) or " first pestilence " was applied , to distinguish the mid-14 th century phenomenon from other infectious diseases and epidemics of plague .


The mechanism by which " Y. pestis " is usually transmitted was established in 1898 by Paul-Louis Simond and was found to involve the bites of fleas whose midguts had become obstructed by replicating " Y. pestis " several days after feeding on an infected host .


When the second population dies , the fleas move on to other hosts , including people , thus creating a human epidemic .


The importance of hygiene was recognised only in the nineteenth century with the development of the germ theory of disease ; until then streets were commonly filthy , with live animals of all sorts around and human parasites abounding , facilitating the spread of transmissible disease .


During 1348 , records show the city of Mosul suffered a massive epidemic , and the city of Baghdad experienced a second round of the disease .


Freckle-like spots and rashes , which could have been caused by flea-bites , were identified as another potential sign of plague .


The disease bypassed some areas , with the most isolated areas being less vulnerable to contagion .


Similarly , Green has argued that greater attention is needed to the range of ( especially non-commensal ) animals that might be involved in the transmission of plague .


Many scholars arguing for " Y. pestis " as the major agent of the pandemic suggest that its extent and symptoms can be explained by a combination of bubonic plague with other diseases , including typhus , smallpox and respiratory infections .


Baghdad has suffered severely from visitations of the plague , and sometimes two-thirds of its population has been wiped out .


One case of a drug-resistant form of the bacterium was found in Madagascar in 1995 .


An estimate of the case fatality rate for the modern bubonic plague , following the introduction of antibiotics , is 11 % , although it may be higher in underdeveloped regions .


Their first line of production took place in Düsseldorf .


An assembly plant was licensed in Ballincollig , County Cork , Ireland between 1952 and c .


After the season , key players like Tim de Cler , Danny Koevermans and Shota Arveladze left the team .


This was a historic achievement for the club as this was the first title-winning season for 28 years , and it also meant a return to the UEFA Champions League .


A week later , John van den Brom was appointed manager .


In December , it was announced free agent Ron Vlaar signed a contract until the end of the season after training with the club for a few weeks prior .


Per the European Federation of Biotechnology , biotechnology is the integration of natural science and organisms , cells , parts thereof , and molecular analogues for products and services .


These processes also were included in early fermentation of beer .


These processes were introduced in early Mesopotamia , Egypt , China and India , and still use the same basic biological methods .


Later , other cultures produced the process of lactic acid fermentation , which produced other preserved foods , such as soy sauce .


Before the time of Charles Darwin 's work and life , animal and plant scientists had already used selective breeding .


The first BioFET was the ion-sensitive field-effect transistor ( ISFET ) , invented by Piet Bergveld in 1970 .


To cite one example , in 1978 Genentech developed synthetic humanized insulin by joining its gene with a plasmid vector inserted into the bacterium " Escherichia coli " .


The results of a genetic test can confirm or rule out a suspected genetic condition or help determine a person 's chance of developing or passing on a genetic disorder .


The regulation of genetic engineering concerns approaches taken by governments to assess and manage the risks associated with the use of genetic engineering technology , and the development and release of genetically modified organisms ( GMO ) , including genetically modified crops and genetically modified fish .


For example , the most common form of congenital adrenal hyperplasia develops as a result of deficiency of 21-hydroxylase , an enzyme involved in an intermediate step of cortisol production .


The adrenal medulla is derived from neural crest cells , which come from the ectoderm layer of the embryo .


These disorders affect the gland either directly ( as with infections or autoimmune diseases ) or as a result of the dysregulation of hormone production ( as in some types of Cushing 's syndrome ) leading to an excess or insufficiency of adrenal hormones and the related symptoms .


When the zona glomerulosa produces excess aldosterone , the result is primary aldosteronism .


In 1981 he left the company and founded Living Videotext to develop this still-unfinished product .


The company was based in Mountain View , CA , and grew to more than 50 employees .


Instead , he froze the format and turned its ownership over to Harvard University .


The term " podcasting " was suggested by Ben Hammersley in February 2004 .


In addition to the deep chestnut colour of their coats , they have bright white stripes on their sides to help with camouflage .


Bongos have two heavy and slightly spiralled horns that slope over their backs , and like many other antelope species , both male and female bongos have horns .


Unlike deer , which have branched antlers shed annually , bongos and other antelopes have pointed horns they keep throughout their lives .


Such habitats may be promoted by heavy browsing by elephants , fires , flooding , tree-felling ( natural or by logging ) , and fallowing .


Bongos require salt in their diets , and are known to regularly visit natural salt licks .


This behavior has also been reported in the okapi .


Tragelaphus eurycerus " may suffer from goitre .


According to reports , these bunyips have round heads resembling a bulldog , prominent ears , no tail , and whiskers like a seal or otter .


The long-necked variety is allegedly between 5 and 15 feet long , and is said to have black or brown fur , large ears , small tusks , a head like a horse or emu , an elongated , maned neck about three feet long and with many folds of skin , and a horse-like tail .


Bunyip eggs are allegedly laid in platypus nests .


Ancient " Diprotodon " skeletons have sometimes been compared to the hippopotamus ; they are a land animal , but have sometimes been found in a lake or water course .


Explorer William Hovell , who examined the skull , also called it a ' katen-pai ' .


With steady success during the remainder of the 1960 s ( both as a solo artist and with a series of duet albums with Porter Wagoner ) , her sales and chart peak came during the 1970 s and continued into the 1980 s .


Most of her cherished memories of youth happened there , and it is the place about which she wrote the song " My Tennessee Mountain Home " in the 1970 s .


Around the same time , Elvis Presley indicated that he wanted to record the song .


Her influence on pop culture is reflected by the many performers covering her songs , including mainstream and crossover artists such as Olivia Newton-John , Emmylou Harris , and Linda Ronstadt .


The result , 1977 's " Here You Come Again , " became her first million-seller , topping the country album chart and reaching number 20 on the pop chart .


The theme song to the 1980 feature film " 9 to 5 " , in which she starred along with Jane Fonda and Lily Tomlin , " 9 to 5 " , not only reached number one on the country chart , but also , in February 1981 , reached number one on the pop and the adult-contemporary charts , giving her a triple number-one hit .


She was also on " The Love Boat " in 1977 , a short cameo in episode 13 as the boat captain 's silent wife .


Although her score ( as well as the musical debut of actress Allison Janney ) was praised , the show struggled , closing on September 6 , 2009 , after 24 previews and 148 performances .


As she suffered from endometriosis , a condition which eventually required her to undergo a hysterectomy , the couple have no children of their own .


For example , hundreds of individuals were found in Lake Callabonna with well-preserved lower bodies , but crushed and distorted heads .


" Diprotodon " superficially resembled a rhinoceros without a horn .


Evidence against the hypothesis is the fact that humans appear to have eliminated the megafauna of Tasmania without using fire to modify the environment there .


" Genetically modified maize " ( corn ) is a genetically modified crop .


The European corn borer causes about a billion dollars in damage to corn crops each year .


In recent years , traits have been added to ward off corn ear worms and root worms , the latter of which annually causes about a billion dollars in damages .


They examined levels of the European corn borer and corn earworm .


A private company Seedco has released 5 MSV cultivars .


While there , he appeared as a guest lead on " Hawaii Five-O " .


He made two appearances in " Charlie 's Angels " .


Having rejected conventional medical treatment , he credited his survival to the adoption of a macrobiotic diet recommended to him by actress Gloria Swanson .


Small samples of rock were extracted from the blast area immediately after the test to study the explosion products , but no isotopes with mass number greater than 257 could be detected , despite predictions that such isotopes would have relatively long half-lives of α-decay .


The latter element was named after Marie Curie and her husband Pierre who are noted for discovering radium and for their work in radioactivity .


It was discovered by Otto Hahn in 1906 .


This may be used to detect if an apparently single star is , in reality , a close binary , to measure the rotational speed of stars and galaxies , or to detect exoplanets .


The prefect of , Poenius Postumus , ignored the call , and a fourth legion , , had been routed trying to relieve , but nonetheless the governor now commanded an army of almost ten thousand men .


The statue was unveiled by David Lloyd George on 27 October 1916 .


After the invention of the telescope , measurements were made by observing occultations of stars by the Moon , which allowed the derivation of more closely spaced and more accurate values for Δ " T " .


The first of their two children , Rebecca , was born September 15 , 1962 .


Son-in-law Daniel Day-Lewis serves on the current board of directors .


A musical child , he sang in the boys ' choir at Salzburg Cathedral where he is believed to have taken music lessons with Michael Haydn .


The firm soon established a reputation in more serious music circles by championing the works of Franz Schubert .


The island is politically divided among three countries : Malaysia and Brunei in the north , and Indonesia to the south .


The largest river system is the Kapuas in West Kalimantan , with a length of .


It is the centre of the evolution and distribution of many endemic species of plants and animals , and the rainforest is one of the few remaining natural habitats for the endangered Bornean orangutan .


By 2001 , transmigrants made up 21 % of the population in Central Kalimantan .


Throughout much of the book she gives details on her side of the sexual harassment controversy , and her professional relationship with Clarence Thomas .


Aside from that , she also provides a glimpse of what her personal life was like all the way from her childhood days growing up in Oklahoma to her position as a law professor .


The company was founded in 1886 as the American Arithmometer Company , and after the 1986 merger with Sperry UNIVAC was renamed Unisys .


B205 tape drives were often seen in series such as " The Time Tunnel " and " Voyage to the Bottom of the Sea " .


James Cameron and Peter Jackson are two directors who publicly reject the label , preferring " extended edition " or " special edition " .


Examples of this architectural style can be found in modern-day Denmark , Germany , Poland , and Russia .


A clear distinction between the two styles only developed at the transition to Baroque architecture .


It was at this time in London that bright red brick was chosen for construction to make the buildings more visible in the heavy fog and to help prevent traffic accidents .


Most buildings in Colombia are made of brick , given the abundance of clay in equatorial countries like this one .


The focus of Air Force Systems Command limited the use of the fighter as a tool with which to train the front line tactical fighter pilots .


In 1995 , the federal government expanded the exclusionary area around the base to include nearby mountains that had hitherto afforded the only decent overlook of the base , prohibiting access to of land formerly administered by the Bureau of Land Management .


Paul Vixie started maintaining it in 1988 while working for Digital Equipment Corporation .


Two months after his divorce , he married Ditta Pásztory ( 1903 – 1982 ) , a piano student , ten days after proposing to her .


He also collected in Moldavia , Wallachia , and ( in 1913 ) Algeria .


Finally , in April 1944 , leukemia was diagnosed , but by this time , little could be done .


Aside from his widow and their son , other attendees included György Sándor .


The two unfinished works were later completed by his pupil Tibor Serly .


Richard argues that inversional symmetry is often a byproduct of another atonal procedure , the formation of chords from transpositionally related dyads .


The first , and still most widely used , is András Szőllősy 's chronological Sz .


On 1 January 2016 , his works entered the public domain in the European Union .


Its range covers the southeastern quadrant of the United States from the Great Lakes and southern Minnesota east to Pennsylvania and southern Massachusetts , and extending west to southern Nebraska , Kansas , Oklahoma , Colorado front-range foothills to 7,000 feet , and all but westernmost Texas .


It is absent from the southern tip of Florida and the highest elevations of the Appalachian Mountains , but occurs in eastern Mexico and in Cuba , Hispaniola , and Puerto Rico .


Isolated populations have been introduced in Oregon and Washington .


The northern bobwhite has also been introduced to New Zealand .


Northern bobwhite were introduced into Italy in 1927 , and are reported in the plains and hills in the northwest of the country .


Extra calcium is required , especially by laying hens ; it can be supplied in the form of shell grit , or cuttlefish bone .


It has long been suggested that there are Japanese quail hybrids being bred commercially ; however , there is a distinct lack of photographic proof to substantiate this .


The northern bobwhite is rated as a Near-threatened species by the International Union for Conservation of Nature .


This is usually the shrub " P. viridis " , Other plant ingredients often or occasionally used in the production of ayahuasca include " Justicia pectoralis " , one of the " Brugmansia " ( especially " Brugmansia insignis " and " Brugmansia versicolor " , or a hybrid breed ) or " Datura " species , and " mapacho " ( " Nicotiana rustica " ) .


Dennis McKenna later studied pharmacology , botany , and chemistry of ayahuasca and oo-koo-he , which became the subject of his master 's thesis .


It may induce intense vomiting and occasional diarrhea .


A diet low in foods containing tyramine has been recommended , as the speculative interaction of tyramine and MAOIs could lead to a hypertensive crisis ; however , evidence indicates that harmala alkaloids act only on MAO-A , in a reversible way similar to moclobemide ( an antidepressant that does not require dietary restrictions ) .


In the late 20th century , the practice of ayahuasca drinking began spreading to Europe , North America and elsewhere .


Also known as a manic episode , mania is a distinct period of at least one week of elevated or irritable mood , which can range from euphoria to delirium .


Mania can also present with increased self-esteem or grandiosity , racing thoughts , pressured speech that is difficult to interrupt , decreased need for sleep , disinhibited social behavior , To meet the definition for a manic episode , these behaviors must impair the individual 's ability to socialize or work .


In severe manic episodes , a person can experience psychotic symptoms , where thought content is affected along with mood .


The onset of a manic or depressive episode is often foreshadowed by sleep disturbance .


Symptoms of the depressive phase of bipolar disorder include persistent feelings of sadness , irritability or anger , loss of interest in previously enjoyed activities , excessive or inappropriate guilt , hopelessness , sleeping too much or not enough , changes in appetite and / or weight , fatigue , problems concentrating , self-loathing or feelings of worthlessness , and thoughts of death or suicide .


In bipolar disorder , a mixed state is an episode during which symptoms of both mania and depression occur simultaneously .


People with bipolar disorder often have other co-existing psychiatric conditions such as anxiety ( present in about 71 % of people with bipolar disorder ) , substance use ( 56 % ) , personality disorders ( 36 % ) and attention deficit hyperactivity disorder ( 10 – 20 % ) which can add to the burden of illness and worsen the prognosis .


This includes increased rates of metabolic syndrome ( present in 37 % of people with bipolar disorder ) , migraine headaches ( 35 % ) , obesity ( 21 % ) and type 2 diabetes ( 14 % ) .


A combination of bipolar I , II , and cyclothymia similarly produced rates of 42 % and 11 % ( identical and fraternal twins , respectively ) .


Less commonly , bipolar disorder or a bipolar-like disorder may occur as a result of or in association with a neurological condition or injury including stroke , traumatic brain injury , HIV infection , multiple sclerosis , porphyria , and rarely temporal lobe epilepsy .


Mental disorders that can have symptoms similar to those seen in bipolar disorder include schizophrenia , major depressive disorder , A key difference between bipolar disorder and borderline personality disorder is the nature of the mood swings ; in contrast to the sustained changes to mood over days to weeks or longer , those of the latter condition ( more accurately called emotional dysregulation ) are sudden and often short-lived , and secondary to social stressors .


The United States spent approximately $ 202.1 billion on people diagnosed with bipolar disorder I ( excluding other subtypes of bipolar disorder and undiagnosed people ) in 2015 .


One analysis estimated that the United Kingdom spent approximately £ 5.2 billion on the disorder in 2007 .


In 2000 , actress Carrie Fisher went public with her bipolar disorder diagnosis .


Several celebrities have also publicly shared that they have bipolar disorder ; in addition to Carrie Fisher and Stephen Fry these include Catherine Zeta-Jones , Mariah Carey , Jane Pauley , and Demi Lovato .


The 2014 ABC medical drama , " Black Box " , featured a world-renowned neuroscientist with bipolar disorder .


The idea was introduced by the architect Christopher Alexander and has been adapted for various other disciplines , notably software engineering .


Christopher Alexander describes common design problems as arising from " conflicting forces " - such as the conflict between wanting a room to be sunny and wanting it not to overheat on summer afternoons .


The Western Armenian affix - է " - ē " ( definite - էն " - ēn " ) derives from the classical singular ; the Eastern Armenian affix - ից " - ic ’ " ( both indefinite and definite ) derives from the classical plural .


Elizabethan scholar John Dee makes references to an occult or angelic language recorded in his private journals and those of spirit medium Edward Kelley .


It occurs as the primary psychoactive alkaloid in several plants including " Mimosa tenuiflora " , " Diplopterys cabrerana " , and " Psychotria viridis " .


DMT is found as a minor alkaloid in snuff made from Virola bark resin in which 5-MeO - DMT is the main active alkaloid .


In a study conducted from 1990 through 1995 , University of New Mexico psychiatrist Rick Strassman found that some volunteers injected with high doses of DMT reported experiences with perceived alien entities .


Since 1955 , DMT has been found in a host of organisms : in at least fifty plant species belonging to ten families , and in at least four animal species , including one gorgonian and three mammalian species ( including humans ) .


As of March 21 , 2009 , a federal judge says members of the church in Ashland can import , distribute and brew ayahuasca .


Some dominatrices practice financial domination , or findom , a fetish in which a submissive is aroused by sending money or gifts to a dominatrix at her instruction .


The props she may brandish will strongly signify her role as dominatrix , such as bearing a flogger , whip or riding crop as illustrated in the artwork of Bruno Zach in the early 20th century , in conventional representation .


He had four plays running simultaneously on Broadway in 1920 .


The RYB model was used for colour printing by Jacob Christoph Le Blon as early as 1725 .


These minerals were crushed , ground into powder , and then mixed with a quick-drying binding agent , such as egg yolk ( tempera painting ) ; or with a slow-drying oil , such as linseed oil , for oil painting .


It was confirmed by Albert Einstein in 1911 .


Raphael was a master of this technique , carefully balancing the reds and the blues so no one colour dominated the picture .


Titian created his rich blues by using many thin glazes of paint of different blues and violets which allowed the light to pass through , which made a complex and luminous colour , like stained glass .


The rise of the colour blue in fashion in the 12th and 13th centuries led to a blue dye industry in several cities , notably Amiens , Toulouse , and Erfurt .


Prussian blue was used by both Hokusai , in his famous wave paintings , and Hiroshige .


J. M. W. Turner experimented with the new cobalt blue , and of the twenty colours most used by the Impressionists , twelve were new and synthetic colours , including cobalt blue , ultramarine and cerulean blue .


Blue was first used as a gender signifier just prior to World War I ( for either girls or boys ) , and first established as a male gender signifier in the 1940 s .


Blue features on the logo of football 's governing body FIFA , as well as featuring highly in the design of their website .


A team from Toronto , Ontario are nicknamed the Blue Jays .


Ten teams prominently feature the colour , with two teams ( Columbus Blue Jackets and St. Louis Blues ) featuring the colour in their nicknames .


Alkaloids have a wide range of pharmacological activities including antimalarial ( " e.g. " quinine ) , antiasthma ( " e.g. " ephedrine ) , anticancer ( " e.g. " homoharringtonine ) , cholinomimetic ( " e.g. " galantamine ) , vasodilatory ( " e.g. " vincamine ) , antiarrhythmic ( " e.g. " quinidine ) , analgesic ( " e.g. " morphine ) , antibacterial ( " e.g. " chelerythrine ) , and antihyperglycemic activities ( " e.g. " piperine ) .


For example , medicinal plants have been known in Mesopotamia from about 2000 BC .


Alkaloids are generated by various living organisms , especially by higher plants " – about 10 to 25 % of those contain alkaloids .


Beside plants , alkaloids are found in certain types of fungi , such as psilocybin in the fungus of the genus " Psilocybe " , and in animals , such as bufotenin in the skin of some toads Many marine organisms also contain alkaloids .


For example , aporphine alkaloid liriodenine produced by the tulip tree protects it from parasitic mushrooms .


In addition , the presence of alkaloids in the plant prevents insects and chordate animals from eating it .


One example of an organism that uses alkaloids for protection is the " Utetheisa ornatrix " , more commonly known as the ornate moth .


Another example of alkaloids being utilized occurs in the poison hemlock moth ( " Agonopterix alstroemeriana ) .


A fire ant venom alkaloid known as solenopsin has been demonstrated to protect queens of invasive fire ants during the foundation of new nests , thus playing a central role in the spread of this pest ant species around the world .


The largest church within the movement - the Seventh-day Adventist Church - had more than 19 million baptized members in 2015 .


of which Sylvester Bliss was the editor until his death in 1863 .


The Seventh-day Adventist Church officially formed in 1863 .


It publishes the " Adventist Review " , which evolved from several early church publications .


The archbishop of Canterbury is also a president of Churches Together in England ( an ecumenical organisation ) .


It is dedicated to W. V. O. Quine , " teacher and friend " .


The use of oil for healing purposes is referred to in the writings of Hippocrates .


A table is prepared , upon which is set a vessel containing wheat .


Anointing may also be given during Forgiveness Vespers and Great Week , on Great and Holy Wednesday , to all who are prepared .


He grew up on the campus of Stanford University , where his father was a professor , and attended the International School of Geneva in 1958 – 59 .


At least by the time of Agaja , the kingdom had developed a standing army that remained encamped wherever the king was .


Eventually , however , the corps became respected enough that King Ghezo ordered every family to send him their daughters , with the fittest being chosen as soldiers .


It was introduced by Nadia Magnenat Thalmann , and Daniel Thalmann .


The philosopher Edmund Burke called the sensation of pleasure derived from pain " sublime " .


In addition , such parties offer both exhibitionists and voyeurs a forum to indulge their inclinations without social criticism .


A 2009 study on two separate samples of male undergraduate students in Canada found that 62 to 65 % , depending on the sample , had entertained sadistic fantasies , and 22 to 39 % engaged in sadistic behaviors during sex .


They were , however , not any more likely to have been coerced , unhappy , anxious , or experiencing sexual difficulties .


Roy Baumeister ( 2010 ) actually had more male masochists in his study than female , and fewer male dominants than female .


These are referred to by a number of ancient authors , including Pausanius ( III , 16 : 10 - 11 ) .


The artists Helmut Newton and Robert Mapplethorpe are the most prominent examples of the increasing use of BDSM-related motives in modern photography and the public discussions still resulting from this .


Critics also object to the wording of the law which puts sado-masochists in the same category as pedophiles and pederasts .


Although examples of literature catering to BDSM and fetishistic tastes were created in earlier periods , BDSM literature as it exists today cannot be found much earlier than World War II .


A common part of many of the poems of Pablo Neruda is a reflection on feelings and sensations arising from the relations of EPE or erotic exchange of power .


In the 21st century , a number of prestigious university presses , such as Duke University , Indiana University and University of Chicago , have published books on BDSM written by professors , thereby lending academic legitimacy to this once taboo topic .


Blizzards can bring whiteout conditions , and can paralyze regions for days at a time , particularly where snowfall is unusual or rare .


In Antarctica , blizzards are associated with winds spilling over the edge of the ice plateau at an average velocity of .


The " Oxford English Dictionary " concludes the term " blizzard " is likely onomatopoeic , derived from the same sense as " blow , blast , blister , and bluster " ; the first recorded use of it for weather dates to 1829 , when it was defined as a " violent blow " .


When the rapidly moving cold front collides with warmer air coming north from the Gulf of Mexico , strong surface winds , significant cold air advection , and extensive wintry precipitation occur .


It killed 400 people , mostly in New York .


After a snowfall lasting nearly a week , an area the size of Wisconsin was entirely buried in snow .


Emperor Napoleon often formed complete divisions out of his 30 dragoon regiments and used them as battle cavalry to break the enemy 's main resistance .


In Japan , in the late 19th century / early 20th century , dragoons were deployed in the same way as in other armies , but were dressed as hussars .


The uniform was designed by Debret , in white and red , with plumed bronze helmets .


The Royal Canadian Mounted Police were accorded the formal status of a regiment of dragoons in 1921 .


After World War II the dragoon regiments were reorganized as armoured reconnaissance units .


Philip V created several additional dragoon regiments to perform the functions of a police corps in the New World .


Among the conditions were a common draft and a championship game played between the two league champions first played in early 1967 , which would eventually become known as the Super Bowl .


On June 9 , 1960 , the league signed a five-year television contract with ABC , which brought in revenues of approximately US $ 2,125,000 per year for the entire league .


As part of the merger agreement , additional expansion teams would be awarded by 1970 or soon thereafter to bring the league to 28 franchises ; this requirement was fulfilled when the Seattle Seahawks and the Tampa Bay Buccaneers began play in 1976 .


Among specific teams , the 1964 Buffalo Bills stood out by holding their opponents to a pro football record 913 yards rushing on 300 attempts , while also recording fifty quarterback sacks in a 14-game schedule .


Clothing designer Louis Réard introduced his new , smaller design in July .


He named the swimsuit after the Bikini Atoll , where the first public test of a nuclear bomb had taken place only four days before .


No runway model would wear it , so he hired a nude dancer from the Casino de Paris named Micheline Bernardini to model it at a review of swimsuit fashions .


Similar photographs were taken of Anita Ekberg and Sophia Loren , among others .


She also posed in a bikini for the glossy " Filmfare " magazine .


For most parts of the Middle East , bikinis are either banned or is highly controversial .


Competitors Natalie Cook and Holly McPeak Many female beach volleyball players have suffered injuries by over-straining the abdominal muscles while many others have gone through augmentation mammoplasty to look appealing in their uniforms .


Sports commentator Jeanne Moos commented , " Beach volleyball has now joined go-go girl dancing as perhaps the only two professions where a bikini is the required uniform .


The 1970 s saw the rise of the lean ideal of female body and figures like Cheryl Tiegs .


As bikinis leave most of the body exposed to potentially dangerous UV radiation , overexposure can cause sunburn , skin cancer , as well as other acute and chronic health effects on the skin , eyes , and immune system .


Notable among his sons are Humayun , Kamran Mirza and Hindal Mirza .


He finally went to Tashkent , which was ruled by his maternal uncle , but he found himself less than welcome there .


In his first marriage , he was " bashful " towards Aisha Sultan Begum , later losing his affection for her .


The couple had one daughter , Fakhr-un-Nissa , who died within a year in 1500 .


The following season also saw the departure of Walter Samuel for € 25 " million and Emerson for € 28 " million , which decreased the strength of the squad .


The club also sold and released defender John Arne Riise , goalkeeper Doni and forwards Jérémy Ménez and Mirko Vučinić .


Notable diseases like smallpox , herpes , and the chickenpox are caused by such DNA viruses .


A virus with a novel method of genome packing infecting species of the genus " Sulfolobus " has been described .


These were isolated from Chile and Australia respectively .


An even larger genus , Pithovirus , has since been discovered , measuring about 1.5 " µm in length .


Isolates from this group have also been isolated from the cerebrospinal fluid and brains of patients with multiple sclerosis .


Ten new circular viruses have been isolated from dragonfly larvae .


A virus with a circular genome - sea turtle tornovirus 1 - has been isolated from a sea turtle with fibropapillomatosis .


A virus has been isolated from the mud flat snail ( " Amphibola crenata " ) .


A circo-like virus has been isolated from the shrimp ( " Penaeus monodon " ) .


The vertebrate herpesviruses initially evolved ~ and underwent subsequent evolution on the supercontinent Pangaea .


The beginnings of Clairvaux Abbey were trying and painful .


North of the city , a fertile and gently undulating steppe extends far north into neighboring Kazakhstan .


The allergen-IgE-FcRε interaction mediates allergic signal transduction to induce conditions such as asthma .


Seeking stable employment , the family migrated from La Libertad to the provincial capital of Juigalpa , and then to a working-class neighborhood in Managua .


We are breaking relations with the terrorist policy practiced by Álvaro Uribe 's government " .


The relations were restored with the resolution at a Rio Group summit held in Santo Domingo , Dominican Republic , on March 7 , 2008 .


The film also stars Sophie Marceau , Patrick McGoohan and Catherine McCormack .


The score was composed and conducted by James Horner and performed by the London Symphony Orchestra .


On Rotten Tomatoes the film has an approval rating of 78 % , with an average score of 7.29 / 10 , based on 81 reviews .


After the war , he worked as a bookseller in Oxford .


and an interview with William S. Burroughs in the second .


Before World War II , destroyers were light vessels with little endurance for unattended ocean operations ; typically a number of destroyers and a single destroyer tender operated together .


At that time , and even into World War I , the only function of destroyers was to protect their own battle fleet from enemy torpedo attacks and to make such attacks on the battleships of the enemy .


The first classes of ships to bear the formal designation " torpedo boat destroyer " ( TBD ) were the of two ships and of two ships of the Royal Navy .


Another house guest was Walter Hayes , vice-president of Ford of Europe .


In 2016 , the company selected St Athan , South Wales as the site of its new factory .


The facility featured three existing ‘ super-hangars ’ of MOD St Athan .


The car was previously driven by Carroll Shelby and Stirling Moss .


In August 1825 , he passed entrance exams at Harvard University , though when the college requested payment of tuition fees for the first two years , he chose not to attend .


He and his commander , Colonel John Selden Roane , had several differences of opinion .


He next joined a Masonic Lodge , where he became extremely active in the affairs of the organization .


She had a number of affairs , her lovers including reporter-turned-playwright Charles MacArthur and the publisher Seward Collins .


It is bordered by Telangana to the north-west , Chhattisgarh to the north , Odisha to the north-east , Tamil Nadu to the south , Karnataka to the west and the Bay of Bengal to the east .


The largest city and commercial hub of the state , Visakhapatnam being the executive capital while Amaravati and Kurnool serve as legislative and judicial capitals respectively .


Hyderabad will remain as a joint capital for not exceeding ten years .


The state has varied topography ranging from the hills of Eastern Ghats and Nallamala Hills to the shores of Bay of Bengal that support varied ecosystems , the rich diversity of flora and fauna .


There are two cities with more than one million inhabitants , namely Visakhapatnam and Vijayawada .


He was succeeded by two other Congressmen , the last resigning over the impending division of Telangana .


Besides rice , farmers also grow jowar , bajra , maize , minor millet , coarse grain , many varieties of pulses , oil seeds , sugarcane , cotton , chili pepper , mango nuts and tobacco .


With a long seacoast along the Bay of Bengal , it also has many ports for sea trade .


The railway station of Shimiliguda was the first highest broad gauge railway station in the country .


In 1938 , they settled in Laugharne , Carmarthenshire , and brought up their three children .


Richard Burton starred in the first broadcast in 1954 , and was joined by Elizabeth Taylor in a subsequent film .


A position further west was unnecessary , as that area of the North Sea could be patrolled by air using blimps and scouting aircraft .


Dozens of crewmen were instantly killed , but far larger destruction was averted when the mortally wounded turret commander – Major Francis Harvey of the Royal Marines – promptly ordered the magazine doors shut and the magazine flooded .


In response to public outrage , the First Lord of the Admiralty Arthur Balfour asked Winston Churchill to write a second report that was more positive and detailed .


During 2000 – 2016 a series of diving and marine survey expeditions involving veteran shipwreck historian and archaeologist Innes McCartney has located all of the wrecks sunk in the battle .


In 1959 , the band received its first glockenspiel from TV host Peter Frankenfeld on the occasion of a TV appearance .


Most probably he had a streptococcal infection and subsequent rheumatic fever leading to valvular heart disease , heart failure and kidney failure .


This was also the first season behind the bench for Jack Adams , who would be the face of the franchise for the next 36 years as either coach or general manager .


The team then lost in the semi-finals to the New York Rangers .


He was succeeded by minor league coach Tommy Ivan .


In 1991 , the team signed free agent Ray Sheppard , who would score a career-best 52 goals three years later .


Also acquired at the trade deadline were defenseman Ulf Samuelsson , winger Wendel Clark , and goaltender Bill Ranford .


Russian prospect Pavel Datsyuk also joined the team .


The team was eliminated in the first round by the Tampa Bay Lightning .


Games are carried on both stations unless there is a conflict with Detroit Tigers baseball .


There are several affiliate stations throughout Michigan and Southwestern Ontario .


The most recent retired number is Red Kelly 's No. 4 , which was retired on February 1 , 2019 .


Plotinus also elucidates the equation of matter with nothing or non-being in " The Enneads " which more correctly is to express the concept of idealism or that there is not anything or anywhere outside of the " mind " or " nous " ( c.f. pantheism ) .


In his study of 1888 , Józef Ignacy Kraszewski wrote that " her tomb was discovered in Gniezno Cathedral .


The logo was redesigned by Massimo Vignelli in 1967 .


Traces of human settlement go back to the Stone Age .


The city is growing dynamically and developing at full speed on an east–west axis along the shores of the Caspian Sea .


Most of the public houses and bars are located near Fountains Square and are usually open until the early hours of the morning .


The track measures 6.003 " km ( 3.735 " mi ) , and it has been on the Formula One calendar since its 2016 debut .


Significant amounts of energy and time were devoted to support and foster the formal study of the balalaika , from which highly skilled ensemble groups such as the Osipov State Russian Folk Orchestra emerged .


In particular , Alexey Arkhipovsky is well known for his solo performances .


SSRIs are a second-line treatment of adult obsessive–compulsive disorder ( OCD ) with mild functional impairment and as first-line treatment for those with moderate or severe impairment .


Antidepressants are recommended as an alternative or additional first step to self-help programs in the treatment of bulimia nervosa .


Similar recommendations apply to binge eating disorder .


Clinical trials have generated mostly negative results for the use of SSRIs in the treatment of anorexia nervosa .


Antidepressants are also used to control some symptoms of narcolepsy .


Antidepressants may be used to relieve pain in people with active rheumatoid arthritis however , further research is required .