Up to 6,500 homes in the Castlemilk and Croftfoot areas of Glasgow and some parts of Rutherglen in South Lanarkshire had been affected.
Some properties lost all water supply, while others experienced low pressure or discoloured water.
A water main in Castlemilk Drive burst at about 07:00 on Saturday.
Scottish Water said engineers were still working on the repair but had been able to restore normal water supplies to the "vast majority" of affected properties.
Homes still without water are likely to be on higher parts of the network.
The company said in a statement: "When normal supplies are restored, affected customers might experience discoloured water as the system recharges.
"If so, customers are advised to run the cold water tap in their kitchen gently until the water starts to run clear.
"Scottish Water apologises to all affected customers for the inconvenience and thanks them for their patience and understanding."
The road where the burst occurred remains closed to allow engineers to work on the pipe.

The Kitchener memorial in Orkney is among those in line for financial assistance.
The monument, which sits on an exposed cliff edge, and faces extensive weathering - is getting £30,000.
Memorials in Helensburgh, Edinburgh, Glasgow, Huntly, Tullibody and Keiss have also received War Memorials Trust funding.
The recipients are:
Frances Moreton, the director of War Memorials Trust, said: "The charity is delighted at the level of interest in this scheme and the enthusiasm of people across the country to do something about the condition of their memorials.
"There are still plenty of funds available for the right projects so get in touch to see if we can help your local war memorial."

Walker was a passenger in the Porsche driven by his friend when it hit a pole and burst into flames in November 2013.
His daughter Meadow filed a wrongful death case in September claiming the carmaker took safety shortcuts.
But Porsche has said the actor "knowingly and voluntarily assumed all risk" of being a passenger in the car.
The star of the high-action Fast and Furious movies was "a knowledgeable and sophisticated user of the 2005 Carrera GT", Porsche said in legal papers filed last week.
"PCNA [Porsche Cars North America] alleges that Mr Walker knowingly and voluntarily assumed all risk, perils and danger in respect to the use of the subject 2005 Carrera GT," said the manufacturer.
It added: "The perils, risk and danger were open and obvious and known to him, and he chose to conduct himself in a manner so as to expose himself to such perils, dangers and risks, thus assuming all the risks involved in using the vehicle."
Porsche also said in its defence papers that the car in which the actor was travelling, had been "abused and altered" and was "misused and improperly maintained".
It adds: "At the time the subject 2005 Carrera GT was originally manufactured, sold and delivered, it comported with state of the art."
After a four-month investigation following the crash on 30 November 2013, the police said the Porsche, driven by Walker's friend Roger Rodas who also died, was travelling at 94mph (151kph) in a 45mph zone when it hit a lamp post.
Meadow Walker's legal claim contends the car was travelling much slower when it went out of control and that her father's seatbelt was defective.
Ms Walker's legal documents allege the car lacked "features that could have prevented the accident or, at a minimum, allowed Paul Walker to survive the crash".
In response to Porsche's defence, a representative for Ms Walker told TMZ: "It is beyond regrettable that Porsche is trying to deflect its own responsibility by blaming the victim, Paul Walker, for his own death by getting into the passenger seat of its Carrera GT.
The statement continued: "Contrary to Porsche's assertions, the facts are clear:  Paul was the passenger in a car that was not designed to protect its occupants, in a crash on a dry, empty straightaway in broad daylight and at speeds well below the vehicle's advertised capabilities."
Mr Rodas' widow filed a similar case last year, but Porsche said the crash was his fault, rather than down to design flaw.
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Water has been restored to most of the homes which lost their supply after a mains pipe burst, Scottish Water has said.
[NEXT_CONCEPT]
Grants totalling £190,000 have been offered to restore 21 First World War memorials across Scotland.
[NEXT_CONCEPT]
Porsche says Fast and Furious actor Paul Walker was responsible for his own death in a high-speed crash of a 2005 Carrera GT.