The victim was found with serious injuries at a house in Unsworth Way in Oldham, Greater Manchester, at about 19:50 GMT on Thursday.
He was taken to hospital and died a short time later. Details of his injuries have not yet been revealed.
The house was cordoned off while police carried out an investigation. A 58-year-old woman has been taken into custody for questioning.

Officers described the incident near Blairhill Station, in Coatbridge, North Lanarkshire, on Sunday night as "stupid and dangerous".
The shopping trolley was hurled through overhead power lines which could have electrocuted the person.
A train hit the trolley, but there was no serious damage to the vehicle or any injuries on board.
British Transport Police have appealed for anyone with information to contact them.
PC Mark Harrington said: "We believe the trolley was thrown onto the tracks before the train struck it.
"It's incredible that whoever threw it was not electrocuted, as the trolley has gone between the overhead wires.
"This was a stupid and dangerous thing to do and could have had very serious consequences, not only for the person throwing the trolley but also for the driver and all the passengers of the train that collided with it.
"This happened in a residential area so it is likely that someone will have seen or heard people by the tracks around the time of the incident.
"I would like to speak to anyone who has any information that could help with this investigation."

The Mystery Plays were first performed in York in the 14th Century and traditionally involve just one professional actor.
The plays will return to the Minster in June 2016. More than 28,000 people attended its last productions in 2000.
The 800-year-old gothic cathedral will host a month-long staging of the plays.
The Very Reverend Vivienne Faull, Dean of York Minster, said: "After a gap of 16 years it is a great pleasure and enormously exciting to confirm the staging of this second, landmark production of the Mystery Plays at York Minster."
In 2014 the plays were staged on wagons travelling around the city's streets.
The plays are described as telling the story of the world from the beginning of all things to the end of all things.
The performances traditionally take place on the feast day of Corpus Christi, which can fall in either May or June.
Nicola Corp, who has worked on projects for the BBC and Capital Radio, has been appointed to produce the event.

Madeley took to Twitter when he spotted the device above the house he shares in Cornwall with his wife, 67-year-old fellow presenter Judy Finnigan.
The star, 59, said he chased the drone user and published his van registration number on the social media site.
Madeley said "minutes after" his tweet the man reported himself to the police.
Devon and Cornwall Police confirmed they were investigating whether a drone had been used legally.
Madeley said the man "called himself in to police with babbled excuses and apologies" following the incident in Talland Bay, near Looe, at about 14:00 BST on Tuesday.
A force spokesman said: "Police are looking into the use of the drone and if it was being used in accordance with the law."
Drones fitted with cameras must not be flown within 50m (164ft) of people, vehicles, buildings or structures, according to the Civil Aviation Authority's code.
A woman has been arrested on suspicion of murdering a 56-year-old man.
[NEXT_CONCEPT]
A person who threw a trolley onto train tracks is lucky to be alive, transport police have said.
[NEXT_CONCEPT]
A centuries-old series of plays performed by amateur actors is set to return to York Minster for the first time in 16 years.
[NEXT_CONCEPT]
TV's Richard Madeley has hailed "Twitterpower" after a "peeping Tom" drone was allegedly flown over the garden of his idyllic seaside home.