One hundred tracks by artists including Ben Howard, Kendrick Lamar and SBTRKT have been shortlisted with voting open until 9pm on 27 November.
Lana Del Rey, You Me At Six and Eminem also feature on the list.
Zane will count down from 100 to one between 1 to 4 December.
The 1975, whose track Chocolate topped the poll in 2013, also appear in this year's list with their track Medicine.
Why'd You Only Call Me When You're High? by Arctic Monkeys and Shadow Moses by Bring Me the Horizon completed the top three last year.
Ed Sheeran's Sing and Stay With Me by Sam Smith, which both went to number one in the UK, also appear on this year's shortlist.
Gecko (Overdrive) by Oliver Heldens and Becky Hill and Clean Bandit's Rather Be, which also topped the chart, feature in this year's top 100 too.
Mercury Prize nominees Bombay Bicycle Club, FKA Twigs, Royal Blood, Jungle and Nick Mulvey all appear as well.
Voting for the 100 Hottest Records is limited to one per person, full terms and conditions can be found on the Radio 1 website.
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Mr Hichilema was due to stand trial, but instead walked free from Lusaka's high court after 100 days in custody.
Sources say the charges against Mr Hichilema and five aides were dropped after a deal was negotiated by the Commonwealth.
He narrowly lost the election to President Edgar Lungu last year.
Mr Hichilema, the leader of the United Party for National Development (UPND), alleges the vote was fixed, and does not recognise Mr Lungu as president.
Mr Lungu, meanwhile, faces accusations of growing authoritarianism.
Mr Hichilema was arrested in April, accused of endangering the president's life after his motorcade allegedly refused to give way to the one transporting Mr Lungu.
He and his aides "strongly" denied the charge, which carries a sentence of at least 15 years. Those found guilty can also be sentenced to death.
But all charges have now been dropped, apparently after a visit by Commonwealth Secretary General Patricia Scotland, who was in Zambia last week and met Mr Lungu and Mr Hichilema.
She later hinted Mr Hichilema could be released in the public interest.
A source had earlier told the BBC he was "definitely being released today... unless there's a last minute development".
Throughout 2014 Zane Lowe has picked his hottest records in the world, and now it's time for you to pick your favourite.
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Zambia's opposition leader Hakainde Hichilema, who has been held in prison since April on treason charges, has been released.