Eighteen people were arrested during the four-day operation and 63 vehicles were seized.
Forty-two of the vehicles had no insurance and/or licence.
A further 21 had no Vehicle Excise Licence, the Hampshire and Thames Valley operation discovered.
Hampshire Constabulary and Thames Valley Police said the joint operation earlier this month aimed to make the roads safer for people living and working in the region.
The "large quantity" of the substance believed to be cocaine was discovered in a car in the Iver and Denham area, officers said.
Other items seized included a stolen digger worth £12,000.
The lorry driver asleep in his cab was in a vehicle "piggy-backing" another vehicle in Portsmouth.
Both drivers were given fines totalling £1,000.

She may continue to exercise some functions, but her role will be very limited.
Sinn FÃ©in has seven days to re-nominate a new deputy first minister following Mr McGuinness' resignation.
However, the party is adamant it will not replace him.
From the evening of Monday 16 January, the baton passes to Northern Ireland Secretary James Brokenshire. The law says he shall call an election.
The usual time period for an Assembly election campaign is six weeks. If Mr Brokenshire moved immediately, then voters in Northern Ireland would be going to the polls in seven weeks' time.
However, a previous court case indicated that the Northern Ireland Secretary did not necessarily need to call an Assembly election immediately, but within a reasonable period of time.
Mr Brokenshire could use this flexibility to allow for more negotiations.
What he cannot do as the law stands is suspend the Stormont Assembly and Executive.
That power was used by previous governments on a number of occasions, but it was removed from the statute book as part of the 2006 St Andrew's Agreement.
It would require a fresh emergency law to be passed by Westminster for suspension to be used again in the future.
During the 2015 crisis over welfare reform and IRA activity, the Northern Ireland Office was adamant that, in the event of a breakdown, it would not try to bring back suspension powers, but allow fresh elections to take place.
Government sources indicate that thinking has not changed, even though a potentially polarising campaign might not make the restoration of devolution in spring any easier.
Sinn FÃ©in say their rift with the DUP is far wider than the latest Renewable Heat Incentive  scandal.
But whilst the Stormont parties go into election mode, it seems unlikely there will be any progress on either recouping the potential RHI losses, or agreeing an independent investigation into the affair.

The 19-year-old has spent the summer on trial in the Championship club's development system.
Phillips was released by Liverpool in May after 10 years at the Anfield club, having joined as a nine-year-old from Blackburn.
"It's a great move for me and a great opportunity to come to a club like Norwich," said Phillips.
Find all the latest football transfers on our dedicated page.
A lorry driver asleep at the wheel and a car thought to be carrying £100,000 of cocaine were among the discoveries made during a police crackdown on motoring offences.
[NEXT_CONCEPT]
Once Martin McGuinness' resignation takes effect, under the joint protocols that govern Stormont's power sharing government, First Minister Arlene Foster also loses her office.
[NEXT_CONCEPT]
Norwich City have signed former Liverpool youngster Adam Phillips on an initial two-year contract.