Greater Manchester Police said the corrosive liquid hit a man and a woman in the eyes on Ashton Old Road, Openshaw, Manchester on Friday evening.
Shortly afterwards, bleach was thrown at a second man on the same road by a passenger in a silver Ford Fiesta heading towards Audenshaw.
Police said those affected were "lucky" to escape serious injury.
Insp Cherie Dunn, of Greater Manchester Police, said: "I am so thankful that none of the victims of these senseless attacks has been seriously injured.
"We could easily have been dealing with life-changing injuries.
"Anyone thinking that throwing bleach at people is funny or that a crime like this does not have consequences couldn't be more wrong.
"The victim's here were lucky. Bleach attacks could have had catastrophic consequences."

It was a second win of the campaign for Pete McGrath's Erne men who had lost three in a row and they move off the foot of the table.
Fermanagh's top scorer Tomas Corrigan limped off early on but Sean Quigley bagged eight points for the hosts with five frees, two 45s and one from play.
Derry are now bottom following their 5-15 to 2-15 defeat away to Galway.
Goals from Benny Heron and Emmett McGuckin helped Derry to a 2-10 to 2-7 lead at the break in Tuam Stadium, with Danny Cummins and Tom Flynn netting for the hosts.
Galway, with the wind in their favour, surged clear in the second half with Johnny Heaney netting before a Eamonn Brannigan penalty and Shane Walsh goal.
Fermanagh's last two matches are Meath away next week and a home match against Derry.
McGrath's men were 0-8 to 0-7 up at half-time and extended that lead with Aidan Breen scoring three points from play.
However, Keelan Sexton palmed in a 46th-minute goal for Clare against the run of play which proved a wake-up call for the hosts.
Fermanagh rattled off five points in a row to seal the valuable victory.
A pregnant woman was among three people targeted when bleach was thrown from a car in two separate attacks.
[NEXT_CONCEPT]
Fermanagh dug deep for a 0-18 to 1-10 win over Clare to boost their chances of survival in Division Two.