A television documentary has alleged Blatter has stayed away from the country since 2011 over a Federal Bureau of Investigation (FBI) probe.
But the 79-year-old Swiss said: "I know that in the US there is an investigation against former people who have been in my government.
"There is nothing against me."
The investigation into alleged football corruption reportedly involves ex-Fifa executive committee members, American Chuck Blazer and Trinidadian Jack Warner.
Blatter added he plans to visit the US in June 2016, to coincide with next year's Copa America tournament.
He last visited the US in May 2011 for a meeting of North American confederation Concacaf, and it had been suggested - including in an ESPN documentary this week - that he had deliberately stayed away since then due to the probe.
However, Blatter, who is currently running for a fifth term as president of football's world governing body, said: "I will be there if elected. Even if not elected, they will invite me I am sure."
Earlier on Friday, Blatter sent a letter to all 209 Fifa member associations identifying several areas where "there is still work to be done", including promoting women's football, combating discrimination and racism, and cracking down on match fixing.
A Fifa spokesman said it was unconnected to Blatter's bid for re-election.
Election rules state that candidates must not mix campaign activities with duties connected to their official positions.
Fifa's member associations will appoint their next president when they meet in Zurich on 29 May.

Desmond D'Mello faces a fitness to practice hearing at the General Dental Council (GDC) next week.
In 2014, more than 22,000 patients in Daybrook, Nottingham, were recalled, with 4,500 tested for viruses.
Mr D'Mello faces 56 misconduct charges including hygiene failures and prescribing antibiotics without seeing patients.
Dental nurse Caroline Surgey - who worked with Mr D'Mello at the Daybrook Dental Surgery - faces 28 similar charges.
A spokesman for the GDC said: "The charges in full against Mr D'Mello allege that in June 2014, he failed to maintain adequate infection control by not wearing gloves, failing to change gloves between patients and other related hygiene issues.
"It is also alleged that Mr D'Mello managed patients in an inadequate manner, including the way in which he issued prescriptions."
This included allegedly prescribing antibiotics without seeing the patient or making a diagnosis.
The pair's hearing is due to start on 8 August and last three weeks.
Mr D'Mello was originally suspended in August 2014 over hygiene concerns. He later volunteered to stop working in the UK.
Thousands were tested for blood borne viruses and five tested positive for hepatitis C.
One of his patients, Amy Duffield, died shortly after treatment but a coroner concluded her death was not connected to the treatment.
Fifa chief Sepp Blatter says he is not being investigated by United States authorities - but admitted former colleagues are.
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Details of the allegations against a dentist involved in the "biggest recall in NHS history" have been released.