After hosting the British Science Festival last year the university wants to capitalise on its success.
Visitors will be able to see demonstrations and workshops based on everyday science through to the latest cutting-edge innovations.
"We continue to inspire the next generation of scientists," said Professor Hilary Lappin-Scott.
The university's senior pro-vice-chancellor added hosting the British Science Festival was an "enormous success" and she wants it to create a "science legacy for Swansea".
It brought tens of thousands of people to the city to celebrate developments and talk about issues affecting our culture and society.
The new festival will be held at the city's National Waterfront Museum from 8-10 September.

A report by NHS Shetland has suggested the move, in a bid to curb excessive drinking.
About three-quarters of all alcohol consumed in Scotland is now bought from supermarkets or off licences.
The proposal will be considered by the local licensing board after the council elections next year.
Elizabeth Robinson, one of the report authors from NHS Shetland, told BBC Scotland: "People with alcohol problems have told us that they can go out the next morning and buy alcohol at 10am.
"If there was just a bit of a longer break until some time in the afternoon that would really help them.
"You can buy your 14 units a week for about Â£3 in Shetland.
"People tend to pour larger drinks at home."
However, shopkeeper Jordan Thomason said: "I think such a drastic increase in time runs the risk of people buying too much alcohol and then it could have the opposite effect of what they are trying to do."

James Tarrant, 66, from Essex, walked into a police station in Breda in the Netherlands on Saturday, the National Crime Agency (NCA) said.
He fled the UK after being arrested in 2009 when drugs, a gun and cash were found at a house in Waltham Abbey.
He was jailed for 15 years in his absence. Extradition proceedings have begun to bring him back to the UK.
The Metropolitan Police first detained Tarrant after finding cannabis blocks, two kilos of cocaine, a handgun, ammunition, body armour and approximately Â£5,000 at a property in Essex.
But he disappeared while on conditional bail.
Tarrant was one of eight "most-wanted" British criminals thought to be hiding in the Netherlands, and was featured on BBC programme Crimestoppers in December.
Dave Allen, head of the NCA's international crime bureau, said: "These fugitives really do have nowhere to hide and I would urge any of the remaining individuals to save yourself the trouble and hand yourself in."
Tarrant was arrested as part of Operation Return, a joint NCA, Crimestoppers, Bel M (Dutch Crimestoppers) and Netherlands law enforcement scheme to locate UK fugitives believed to be hiding out in and around Amsterdam.

Doug Paulley, from Wetherby, was denied access to a First Group bus when a woman with a pushchair refused to move.
Senior judges overturned an earlier ruling which said the firm's wheelchair policy was discriminatory and breached the Equality Act.
Mr Paulley has now lodged permission to appeal papers with the Supreme Court.
According to the appeal papers the Court of Appeal's decision was "wholly inconsistent with the policy of the Equality Act 2010".
Mr Paulley said he was prepared to take the case "as far as it needs to go".
"Disabled people chained themselves to buses in the 1990s to make sure accessible buses were put on routes, but there's no point in having them if you can't use them," he said.
In 2013 Leeds County Court ruled First Group's "first come first served" policy was unlawful and said disabled users should have priority access to wheelchair spaces.
However, last year the Court of Appeal said the "proper remedy" for wheelchair users to get improvements was to ask Parliament.
A spokeswoman for solicitors Unity Law, which represents Mr Paulley, said First Bus Group had indicated it objects to the application.
She said a panel of Law Lords will have to consider whether to allow the appeal.
Mr Paulley's case is being supported and funded by the Equality and Human Rights Commission (EHRC).
A spokeswoman said: "This case is of enormous importance to the thousands of wheelchair users who may wish to use public transport such as buses without having the anxiety of being told they cannot travel because the space is being occupied by buggies."
First Group told the BBC it was preparing a response.
Swansea University will celebrate its achievements and research by holding a new science festival in September.
[NEXT_CONCEPT]
A proposal that supermarkets and off licences should only be able to sell alcohol later in the day is to be considered in Shetland.
[NEXT_CONCEPT]
A convicted drugs trafficker who has been on the run for five years has handed himself into Dutch police.
[NEXT_CONCEPT]
A disabled man who won a court ruling over bus wheelchair access which was later overturned has launched a bid to take the case to the Supreme Court.