Posting a picture of a letter addressed to "Mrs Clegg" on Instagram, she noted the "irony" of the situation.
The event, on 8 March, is designed to "celebrate women's success", she added.
Ms Gonzalez Durantez is a lawyer specialising in international and EU trade law.
She wrote: "The irony of being invited to speak at an International Women's Day event to celebrate women's success, addressed to me as 'Mrs Clegg'."
Ms Gonzalez Durantez set up the Inspiring Women group, which recruits women with successful careers to visit and speak to girls at state schools in England.
This is not the first time she has criticised the way she is perceived or described.
Last year she told Marie Claire magazine: "I find people say of me 'She wears the trousers' and as you can see, it is true, I have very nice trousers.
"Or if my husband and I share the school run, it's me who has forced him, dragged him away from his work.
"But when people, or in my case the media, are using that label on you, they are not saying you are strong, they are saying you should get back in your box. You should make the dinner and have his slippers ready with a gin and tonic."

Tech stocks had fallen on Friday and Monday, with some analysts saying that share prices in the sector had become overblown.
But after dropping 2.5% on Monday, shares in tech giant Apple were up 1.2% at the close.
Google owner Alphabet was also up 1.1% while shares in social media giant Facebook rose 1.5%.
The tech-focused Nasdaq index rose 44.90 points, or 0.7%, to 6,220.37.
The Dow Jones climbed 93.28 points to 21,328.95, while wider S&P 500 index added 10.96 points to 2,440.35, with both indexes setting fresh record highs.
Traders expect an interest rate increase when the Fed concludes a two-day meeting on Wednesday.
Miriam Gonzalez Durantez, whose husband is former Deputy Prime Minister Nick Clegg, has complained after being invited to an International Women's Day event in her married name.
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Stocks on Wall Street have closed higher, with tech stocks recovering some of the ground lost in recent days.