The show's creator, Ryan Murphy, tweeted the announcement saying: "Kathy Bates is running the Hotel. â€ª#AHSSeason5."
It's unclear exactly what her job will be, but it sounds like she'll be in charge of the hotel.
The 66-year-old actress played lead roles in previous seasons American Horror Story: Coven and American Horror Show: Freak Show.
Chloe Sevigny, Lady Gaga, Wes Bentley, Matt Bomer and Cheyenne Jackson all have parts in the fifth series.
Kathy Bates played a bearded lady, Ethel Darling in Freak Show and won an Emmy for her role in Coven playing Madame Delphine Lalaurie.
The actress is arguably best known for her role as a psychopathic nurse in Misery in 1990 for which she won the best actress Academy Award and a Golden Globe.
She later received two more Oscar nominations for 1998's Primary Colors and 2002's About Schmidt.
Filming for AHS: Hotel is expected to begin in the next few months with the premiere in October.
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Trescothick made 153 and Abell hit 131 - his maiden first-class hundred - as they put on 272 for the first wicket.
Cooper struck 118 at number three and James Hildreth made 71 as the hosts built a huge first innings lead of 329.
Somerset, who led eighth-placed Hampshire by five points at the start of play, have eight bonus points.
Hampshire on the other hand have only taken one batting and one bowling bonus point from the game.
Resuming on 147-0, Trescothick and Abell took the hosts past Hampshire's first innings total of 240 before Abell was trapped lbw by Gareth Berg.
Skipper Trescothick, who signed a new one-year deal with the county on Wednesday, struck 29 fours in his 261-ball innings which came to an end when he was bowled by West Indies paceman Fidel Edwards.
Cooper then continued the fine work of the openers in glorious batting conditions as he brought up his first century for Somerset off just 103 deliveries and put on 142 with Hildreth.
Hildreth passed 1,200 Championship runs for the season before he was bowled by Liam Dawson (3-130) shortly before the close on a day in which 422 runs were scored.

The visitors went behind early when goalkeeper Tom King fumbled Andy Haworth's corner and presented Jason Walker with a close-range gift.
Andy Cook doubled the advantage with his 20th goal of the season as he latched on to Jordan Williams' assist.
Barrow have now gone nine games unbeaten while defeat leaves Braintree are one point off the top five.
Kathy Bates is to star in the new series of American Horror Story: Hotel.
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Marcus Trescothick, Tom Abell and Tom Cooper all hit centuries as Somerset piled up 569-5 on day two against relegation rivals Hampshire at Taunton.
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Barrow registered a fourth successive win as they dented Braintree's National League play-off hopes.