The first minister will say Wales needs two Labour governments to ensure the economy works "for everyone".
The party says it will deliver tidal lagoons, rail electrification and the Wylfa Newydd Nuclear Plant.
It will also create a Development Bank of Wales, if in power in Cardiff and London.
The party says it will ensure the level of funding Wales currently receives from the European Union continues beyond Brexit.
Welsh Labour has so far been attempting to run a largely separate election campaign, fronted by First Minister Carwyn Jones rather than UK leader Jeremy Corbyn.
At a launch for the campaign in Cardiff two weeks ago, Mr Jones made no reference to Mr Corbyn, and three of the five pledges unveiled related to the work of the Labour-run Welsh Government in Cardiff Bay, rather than issues under Westminster control.
Speaking at the launch in the Delyn constituency in north Wales later today, Mr Jones will say: "Our manifesto is an ambitious, comprehensive plan of what Welsh Labour can do, together, working in the assembly and Westminster."
He will add: "Working in partnership, Welsh Labour will commit to protecting the funding that would have come to Wales through the EU.
"That money will be spent in Wales, and on Welsh priorities, and not stashed away in Whitehall as the Tories now threaten."
The first minister will say a Labour government at Westminster would ensure an "estimated Â£1.5bn extra" will come to Wales every year.
The general election manifesto says Welsh Labour will also work with a UK Labour government to abolish the Severn bridges tolls and hand over responsibility for policing from Whitehall to the Welsh Assembly.

The former presidential candidate will release her untitled tome on 26 September, says Simon & Schuster. Financial terms were not revealed.
The publisher said Mrs Clinton will use some of her favourite quotes to "tell stories from her life".
The Democrat lost the election to Republican Donald Trump in a stunning upset, even though she won more votes.
"These are the words I live by," former secretary of state Mrs Clinton said in a statement of her forthcoming book.
"These quotes have helped me celebrate the good times, laugh at the absurd times, persevere during the hard times and deepen my appreciation of all life has to offer.
"I hope by sharing these words and my thoughts about them, the essays will be meaningful for readers," she added.
The 69-year-old is also resuming her relationship with the Harry Walker Agency, the speakers' bureau she left in 2013 as secretary of state.
Her money-spinning career as a speaker, including talks sponsored by Goldman Sachs, were a festering subject of criticism from political opponents.
She is set to speak at an International Women's Day event next month organised by Vital Voices, an organisation founded by Mrs Clinton and then-Secretary of State Madeleine Albright in 1997.
The event was not organised by the Harry Walker Agency, according to Clinton spokesman Nick Merrill.
Her plans to return to that agency are seen as making it unlikely that she might launch a bid for the mayoralty of New York City, as Clinton-watchers have speculated.
She is also set to appear at an LGBT community centre gala in New York on 20 April and deliver the commencement address at her alma mater, Wellesley College.
Mrs Clinton has kept a low profile since the election, but attended Mr Trump's inauguration last month and has criticised his policies.
Welsh Labour is promising a "real partnership" with a Labour government in Westminster as it launches its manifesto on Monday.
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Hillary Clinton is writing a book of personal essays, including reflections on last year's US election.