Matthew Cryer, 17, from Killamarsh, north Derbyshire, suffered head injuries outside a bar in the beach resort of Laganas in 2008.
At the time, Greek police said he died from excessive drinking, but a UK inquest heard evidence he had been attacked and sustained 20 injuries.
Lawyers for Matthew's family have now said charges could be imminent.
His family has campaigned for justice since his death, and in 2011 police on the Greek island reopened the case.
This week, his mother Jo Froud said she had been told that prosecutors are close to charging suspects with exposure to harm.
Mrs Froud said if a prosecution went ahead, it would then be for a judge to decide whether the case should go to a trial.
"There's still a small possibility that it might not go ahead so we can't get our hopes up just yet," she said.
"We have waited for so long now. Over the years we have had to develop patience and the art of compromise.
"Matthew will always be missing from our lives and there's nothing we can do about that, but if we can get this court case and what we think is a reasonable kind of justice for him, then we can move forward."
An inquest in Chesterfield in 2009 found Matthew was unlawfully killed. A coroner said he had been dragged from inside the nightclub, attacked and allowed to fall down steep steps outside.
The coroner at the time criticised Greek authorities saying no attempts were made to find out how Matthew sustained his fatal injuries.

The victim, in his 30s, was shot in Swancote Green, Bracknell after answering the door to two men at about 18:00 BST last Sunday.
He was treated in hospital and later released.
Police said 28-year-old Scott Kennedy of Sturdee Close, Frimley, Surrey, is accused of one count of attempted murder.
A 63-year-old man, also from Frimley, Surrey, arrested in connection with the shooting has been bailed until 26 June.
Mr Kennedy is due to appear before Reading Magistrates' Court.

The slow left-armer, who had managed only six wickets in his previous 17 Tests, helped dismiss India after tea despite the home side winning the toss.
Murali Vijay top-scored with 75, while leg-spinner Imran Tahir claimed 2-23.
South Africa struggled to 28-2 in the 20 overs possible before the close, with opener Elgar unbeaten on 13.
Off-spinner Ravichandran Ashwin, opening the bowling, trapped Stiaan van Zyl lbw for five before Faf du Plessis - also playing no shot - was bowled by Ravindra Jadeja.
Nine of the 12 wickets in the day fell to spin, with Vijay - lbw attempting to sweep Simon Harmer - part of a collapse from 102-3.
"This is not a good Test pitch wicket though it's a result-oriented one," said Elgar. "We sort of expected it to play like that but we didn't expect it to crumble so early.
"It was right up there with the hardest ever Test cricket I've played. Let's hope that it backfires [on India] and turns out to be a great victory for us."
India's batting coach Sanjay Bangar responded: "It's a very challenging wicket where run-making is not easy.
"It says 201 runs on the scoreboard but it's worth far more. But I think runs can be made on this wicket as Vijay showed. It's going to be a test of patience both for batsmen and bowlers."
This Test is followed by matches in Bangalore, Nagpur and Delhi.
The family of a teenager who died while on holiday in Zante five years ago are hopeful of a breakthrough in the case.
[NEXT_CONCEPT]
A man has been charged with the attempted murder of a man who was shot in the chest at his Berkshire home.
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Part-time spinner Dean Elgar took 4-22 as South Africa bowled out India for 201 in Mohali, on the opening day of the four-Test series.