GPT
GPT may refer to:

Computing
 Generative pre-trained transformer, a type of artificial intelligence language model
 ChatGPT, a chatbot developed by OpenAI, based on generative pre-trained transformer technology
 GUID Partition Table, a disk partitioning standard

Biology
 Alanine transaminase or glutamate pyruvate transaminase
 Goniopora toxin
 UDP-N-acetylglucosamine—undecaprenyl-phosphate N-acetylglucosaminephosphotransferase

Companies
 GEC Plessey Telecommunications, a defunct British telecommunications manufacturer
 GPT Group, an Australian property investment company

Other uses
 Gulfport–Biloxi International Airport, in Mississippi
 General-purpose technology, in economics
 Generalized probabilistic theory, a framework to describe the features of physical theories
 Grounded practical theory, a social science theory