Manion
Manion may refer to:

 Clarence Manion, American conservative and Dean of Notre Dame. Daniel Anthony Manion (born 1942), United States federal judge for the United States Court of Appeals for the Seventh Circuit
 Ed Manion, American saxophone player
 Jack Manion (1877–1959), San Francisco Police Sergeant
 John Manion (born 1931), retired Canadian civil servant
 Katherine Manion (1867–1956), American physician
 Robert James Manion (1881–1943), leader of the Conservative Party of Canada
 Manyam Zamindar of French Yanam. See also
 Mannion
 James Mannon, American sociologist