7-Methylxanthine
7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). It is a non-selective antagonist of the adenosine receptors. The compound may slow the progression of myopia (nearsightedness). It is under investigation for this purpose in children with myopia. It is shown that systemic treatment with 7-mx appears to be efficient in retarding axial elongation and myopia progression among myopic children. The treatment is safe and without side effects, and may be continued until 18–20 years of age, when age-related cross-linking of collagen prevents further elongation of the eye. Additionally, further studies show that oral intake of 7-MX was associated with reduced myopia progression and reduced axial elongation in this sample of myopic children from Denmark. Randomised controlled trials are needed to determine whether the association is causal. Further clinical trials will be conducted to ascertain the full efficacy of this new drug for the use of controlling the progression of Myopia. References 

Adenosine receptor antagonists
Experimental drugs
Human drug metabolites
Ophthalmology drugs
Xanthines