Mariana J. Kaplan
Mariana J. Kaplan is a rheumatologist and physician-scientist. She researches mechanisms of immune dysregulation, organ damage, and premature vascular disease in systemic autoimmunity. Kaplan is chief of the systemic autoimmunity branch at the National Institute of Arthritis and Musculoskeletal and Skin Diseases. Life 
Kaplan obtained her medical degree at the National Autonomous University of Mexico and did her internal medicine residency at the Salvador Zubirán National Institute of Health Sciences and Nutrition. She completed a rheumatology fellowship and postdoctoral training at the University of Michigan, where she was a member of the faculty for fifteen years and an active member of their multidisciplinary lupus clinic. She was a professor of medicine in the division of rheumatology at the University of Michigan. In 2013, Kaplan joined the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) as chief of the systemic autoimmunity branch. She is also deputy scientific director. Kaplan's research has focused on identifying mechanisms of immune dysregulation, organ damage, and premature vascular disease in systemic autoimmunity. She investigates how innate immunity (in particular, type I interferons and myeloid cells) promote autoimmune responses and end-organ damage in systemic lupus erythematosus, rheumatoid arthritis, and other systemic autoimmune diseases. Kaplan was inducted into the American Society for Clinical Investigation and the Association of American Physicians. In 2021, she was elected to the National Academy of Medicine for seminal contributions that have significantly advanced the understanding of the pathogenic role of the innate immune system in systemic autoimmune diseases, atherosclerosis, and immune-mediated vasculopathies. References 

Living people
Year of birth missing (living people)
Place of birth missing (living people)
National Autonomous University of Mexico alumni
University of Michigan faculty
National Institutes of Health people
21st-century American women physicians
21st-century American physicians
Mexican emigrants to the United States
Mexican medical researchers
Women medical researchers
American medical researchers
Physician-scientists
American rheumatologists
Mexican women physicians
21st-century Mexican physicians
Members of the American Society for Clinical Investigation
Members of the National Academy of Medicine
Hispanic and Latino American women scientists