Port Isabel
Port Isabel may refer to:

Places
Port Isabel, Texas, USA; a city in Cameron County
Port Isabel, Sonora, Mexico; a former port (1864-1879) at the mouth of the Colorado River
Port Isabel Independent School District, Cameron County, Texas, USA
Port Isabel Slough, Sonora, Mexico; a slough in the Colorado River

Facilities and structures
Port Isabel-Cameron County Airport, Texas, USA
Port Isabel Air Force Station, Brownsville, Texas, USA
Port Isabel Detention Center, Los Fresnos, Texas, USA; a federal ICE detention center
Port Isabel High School, Port Isabel, Texas, USA

See also

 Point Isabel (disambiguation)
 Isabel (disambiguation)
 Port (disambiguation)