1-up (disambiguation)
A 1-up, or extra life, is a video game item. 1-UP, 1UP, 1Up, or one-up may also refer to:
 1Up.com, a defunct video game website
 1UP!, a 2009 album by illScarlett
 1UP (T-Pain album), a 2019 album by T-Pain
 1-Up Studio, a Japanese video game studio formerly known as Brownie Brown
 One-upmanship, successively outdoing a competitor
 1Up (film), a movie from 2022