USY
USY may refer to:

 United Synagogue Youth, a Jewish youth group
 University of Sanya, a Chinese university
 USY, the Uyghur Cyrillic alphabet
 Usy, Tatarstan, a place in Russia
 Ultrastable zeolite Y, high-silica synthesized faujasite that had its aluminium removed

See also 
 Usie, a term for group selfies
 United States Youth Soccer Association (USYS), a youth soccer organization