VVO2max
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vV̇O2max (velocity at maximal oxygen uptake), also known as maximal aerobic speed (MAS), is an intense running or swimming pace. This is the minimum speed for which the organism's maximal oxygen uptake (VO2 max) is reached, after a few minutes of constantly maintaining this exercise intensity. At higher paces, any additional increase in power is provided by anaerobic processes. In an incremental exercise test, it is the first speed at which any increase in exercise intensity fails to elicit an increase in oxygen consumption. The vV̇O2max of world class middle- and long-distance runners may exceed  or 2:30/km pace ( or about 4:00/mile), making this speed slightly comparable to 3000 m race pace. For many athletes, vV̇O2max may be slightly slower than  or mile race pace. Measuring vV̇O2max 

While a sophisticated lab may be required to obtain precise measures of vV̇O2max, it can be estimated using a simple field test on a 400 m running track. In a 2015 study of 28 male rugby players, the authors measured vV̇O2max and then had the subjects perform short time trials (TT) of various distances on the track. Using the average speed of a 2000 m TT gave the best estimate of vV̇O2max, with the limits of agreement estimated as ±5%. For a better estimate, several time trials at distances varying from 1200–2200 m could be run, with adequate rest between them (e.g. 48 h in Bellenger et al.). Then vV̇O2max may be estimated from the following linear equation

vV̇O2max = TTs × (0.117 × TTd + 0.766)

where TTs is the average time trial speed, and TTd is the time trial distance in km. Training at vV̇O2max 
Research by Véronique Billat has shown that training at vV̇O2max pace improves both V̇O2max and the economy required to maintain pace at this intensity. Training at vV̇O2max takes the form of interval workouts. For example, 3 ×  with 3 minutes recovery between each repetition. Determining vV̇O2max from VO2max 
The formula from Léger and Mercier links the V̇O2max to the vV̇O2max, supposing an ideal running technique. vV̇O2max = V̇O2max / 3.5
where vV̇O2max is in km/h and V̇O2max is in mL/(kg•min). Note: This formula is identical to that used to calculate the metabolic equivalent of task (MET) score for a given V̇O2max estimation. See also 
High-intensity interval training
Lactate threshold
Respirometry
Running economy
Training effect
VDOT

References

Exercise physiology
Running