Histamine agonist
A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes. H2: Betazole and Impromidine are examples of agonists used in diagnostics to increase histamine. H3: Betahistine is a weak Histamine1 agonist and a very strong antagonist of the Histamine3 autoreceptor. Antagonizing H3 increases histaminergic tone. See also
 Histamine antagonist

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