Tympanic membrane retraction
Tympanic membrane retraction describes a condition in which a part of the eardrum lies deeper within the ear than its normal position. The eardrum comprises two parts: the pars tensa, which is the main part of the eardrum, and the pars flaccida, which is a smaller part of the eardrum located above the pars tensa. Either or both of these parts may become retracted. The retracted segment of eardrum is often known as a retraction pocket. The terms atelectasis or sometimes adhesive otitis media can be used to describe retraction of a large area of the pars tensa. Tympanic membrane retraction is fairly common and has been observed in one quarter of a population of British school children. Retraction of both eardrums is less common than having a retraction in just one ear. It is more common in children with cleft palate. Tympanic membrane retraction also occurs in adults. Attempts have been made to categorise the extent of tympanic membrane retraction  though the validity of these classifications is limited. Presentation 
The majority of tympanic membrane retractions do not cause any symptoms. Some cause hearing loss by restricting sound-induced vibrations of the eardrum. Permanent conductive hearing loss can be caused by erosion of the ossicles (hearing bones). Discharge from the ear often indicates that the retraction pocket has developed into a cholesteatoma. Pathogenesis 
Three factors must occur for the tympanic membrane to become retracted:

Negative middle ear pressure 

When gas pressure within the middle ear is less than atmospheric pressure, the eardrum can become sucked into the middle ear space. This may be caused by disrupted gas exchange in the middle ear mucosa, inadequate opening of the Eustachian tube or a combination of these factors. People with a patulous Eustachian tube may also cause negative middle ear pressure by repeatedly sniffing to try to keep their Eustachian tube closed. Weakness of the tympanic membrane 

The middle layer of the pars tensa is strengthened by fibers of collagen protein. This layer may be weaker in the postero-superior quadrant (top rear quarter) or after the eardrum heals after perforation or tympanostomy tubes (grommets) so predispose to retraction in these areas. The pars flaccida is prone to retraction as it does not contain the same stiffening layer of collagen. Increase in surface area of the tympanic membrane 

All over the body, new skin cells are continually produced to replace old skin cells which dry out and slough off. Growth of new cells on the surface of the eardrum is unusual in that the new cells migrate over the surface and move out along the ear canal. Even if migration along the ear canal is blocked, new cells continue to grow so the surface of the eardrum becomes larger. This process of proliferation and migration can result in enlargement of a retraction pocket so that the eardrum expands and grows deeper into the ear. Natural history 
The majority of tympanic membrane retractions remain stable for long periods of time, or may even resolve spontaneously so that the eardrum becomes normal again. Not all retractions are able to resolve even if middle ear pressure normalizes, as the retracted segment may become adherent to other structures within the middle ear. Some retractions continue to progress and grow more deeply into the ear. This can result in erosion of bone and cholesteatoma formation. Asymptomatic deep pars tensa retractions tend to remain stable in adults. However, behaviour of symptomatic pars tensa retractions significantly differ between children and adults. There is a likelihood that such ears in children will recover spontaneously. There is no simple clinical means of identifying which ears will deteriorate to accumulate keratin debris in the pars tensa retraction, a phenomenon that is not influenced by age. In children, the pars tensa retraction may remain unchanged while the pars flaccida deteriorates to form cholesteatoma. Bone erosion  

As the middle ear is only a narrow space, the eardrum only has to retract a short distance before it touches boney structures within the middle ear such as the ossicles. It may become adherent to these bones and in some cases, this contact leads to erosion of the bone. As well as ossicular erosion, the bone of the ear canal (e.g. the scutum) and even bone over the cochlea (the promontory) can become eroded. Keratin entrapment 

As skin cells die they form a barrier of dry protein called keratin. This layer of keratin is normally pushed out of the ear by migration of skin cells along the ear canal and is turned into wax. Clearance of keratin can be disrupted by tympanic membrane retraction so that keratin accumulates within the retraction pocket. When keratin becomes trapped deep inside the ear and cannot be cleaned out, it is known as cholesteatoma. Growth of bacteria in the trapped keratin causes smelly discharge from the ear and can spread to cause serious infection. Treatment 
Various strategies may be used to manage tympanic membrane retraction, with the aims of preventing or relieving hearing loss and cholesteatoma formation. Observation 

As retraction pockets may remain stable or resolve spontaneously, it may be appropriate to observe them for a period of time before considering any active treatment. Increase middle ear pressure 

The Valsalva maneuver increases middle ear pressure and can push a retracted eardrum out of the middle ear if it is not adherent to middle ear structures. Hearing may improve as a result, however it can be a painful maneuver. The benefits are typically only temporary. Middle ear pressure can also be increased by Politzerization and with commercially available devices (e.g. Otovent and Ear Popper). Ventilation tubes 

A ventilation tube, also known as a tympanostomy tube or a grommet, may be placed through the eardrum to equalize middle ear pressure. Although this intervention may be effective, research has not yet shown whether it provides better results than simple observation. Further weakness or perforation of the eardrum may occur. Nasal treatments 

These are intended to improve Eustachian tube function. Adenoidectomy can improve middle ear function  and nasal steroid sprays can reduce adenoid size  but it is not known whether these treatments alter tympanic membrane retraction. Eustachian tube surgery 

Enlargement of the Eustachian tube opening in the nose with laser or balloon dilatation is being evaluated as a potential treatment for tympanic membrane retraction. There are two methods for this technique: Dennis Poe popularized the transnasal introduction of the balloon catheter to dilate the distal (nose end of the Eustachian tube). Muaaz Tarabichi pioneered the  dilatation of the proximal (ear side of the eustachian tube) through transtympanic (trans-ear) introduction of the balloon catheter. Retraction pocket surgery 

Excision of the retracted segment of an eardrum, with or without placement of a tympanostomy tube has been advocated. Healing of the area can result in a more normal eardrum. Laser therapy has been used to shrink and stiffen retraction pockets. Tympanoplasty 

Tympanoplasty is the surgical technique of removal of the retracted area from the middle ear and reconstruction of the tympanic membrane. Some surgeons use cartilage (taken from the outer ear) to stiffen the eardrum with the aim of preventing further retraction. Surgical removal is required once a cholesteatoma has formed. References

Diseases of middle ear and mastoid