Thofania d'Adamo
Thofania d'Adamo or Teofania di Adamo, Epifania d'Adamo or La Tofania (died 12 July 1633, Palermo) was an Italian poisoner. Case
She was executed for having poisoned her late spouse Francesco d'Adamo and for having trafficked in illegal lethal poison. She was preceded by Francesca La Sarda, who was executed for having trafficked in illegal lethal poison the year prior. The two women were accused to have sold poison together in Palermo. The case attracted a lot of attention and the investigation was conducted on the orders of Fernando Afán de Ribera. Legacy
The case is first mentioned in the Compendio di diversi successi in Palermo dall’anno 1632 by Baldassare Zamparrone (1581-1648). The contemporary diarist Gaetano Alessis described in Notizie piacevoli e curiose ossia aneddoti…, in which he claimed that the poison Aqua Tofana was invented by her and named after her. Thofania d'Adamo are known in history as the alleged mother of the famous poisoner Giulia Tofana. According to legend, Giulia Tofana fled to Rome after the execution of her mother Thofania d'Adamo, founded a new business selling poison in Rome, and named the poison Aqua Tofana after her mother. However, this appears to have been a myth, inspired by an hypothesis in the 19th-century. Giulia Tofana, whose actual name was Giulia Mangiardi, left Palermo for Rome in 1624 and not 1633; and while she does appear to have founded a business selling poison In Rome, which she eventuelly left to her stepdaughter Gironima Spana, there is nothing to indicate that Thofania d'Adamo was the mother of Giulia Mangiardi, although she may have been her disciple. References

Philip Wexler, Toxicology in the Middle Ages and Renaissance

1633 deaths
17th-century Italian businesswomen
17th-century Italian criminals
17th-century executions
Executed Italian serial killers
Executed Italian women
Italian female serial killers
Mariticides
People executed by Italy by hanging
People executed by the Kingdom of Sicily
People executed for witchcraft
People from Palermo
Poisoners
17th-century Italian businesspeople