jacquesm is right, there&#x27;s no actual scientific breakthrough here. We already know glutaraldehyde does a good job of preserving synaptic structure, that&#x27;s why we have used it to fix brains for electron microscopy analysis for roughly a century. I guess it&#x27;s cool that you can freeze a glut-fixed brain and then unfreeze it and that won&#x27;t have a dramatic effect on the structure. I&#x27;d be interested to know how quantitative their analysis was. Absence of evidence (of deformed synapses) is not evidence of absence. But anyways the synaptic ultrastructure probably isn&#x27;t everything. It&#x27;s necessary but not sufficient.