<i>Performers with stage fright have been using beta blockers for year as an off-label treatment for performance anxiety.</i><p>I read about that a few years ago, so gave it a go before high-pressure situations where, previously, my mind and attitude were fine but my body was going nuts, and.. the fight-or-flight response has either been heavily diminished or even absent. I consider them a major win with only occasional (several times a year) low dose use but YMMV.