There are lots of major advances left. You can&#x27;t look at the past or present as a way of saying there are no major advances left. People throughout history could and have done this, only to be proven wrong. Don&#x27;t equate breakthroughs&#x2F;advances with scientific research, a lot of the breakthroughs and advances we take for granted today came out of some random human beings imagination. Disruptive breakthroughs does not take the game incremental and linear ahead through a predictable path - it shows a path no one before had thought of existed or even though possible.