There are a ton of SBIR rules so you&#x27;ll have to be prepared with your accounting system, timekeeping policies for employees and other legal contracting.<p>First, check your company&#x27;s eligibility.  If you&#x27;re VC backed then I&#x27;m not sure your company is eligible for the SBIR program.  I remember there being some proposed changes but I&#x27;m not sure they were made official or not regarding VC-funded small businesses.  Also be aware that you are granting the government certain rights to the intellectual property that is generated under contract.  You can still commercialize based on that IP, but the government has some rights to use of that software.<p>If you want a general overview of the program I think you can google for the &quot;SBIR Coach&quot; and he has some free online resources that give an overview of the program.<p>If you&#x27;re planning to submit a proposal to an RFP, make sure to very carefully read all the instructions in the solicitation regarding formatting and everything.<p>Many government agencies participate in the SBIR program.  Which agency are you considering submitting a proposal for?<p>Let me know if you have more specific questions.  I worked in the SBIR industry for about 8 years.