Well you really shouldn&#x27;t be serving static content through Django, you should be serving it through a CDN. If you use something like Django-Storages for uploads, it&#x27;ll Just Work.<p>I&#x27;m not guaranteeing that everything will work out of the box on the first try, but I bet you&#x27;ll be very close. You  will have to make a few design decisions, but if you&#x27;re making the right ones it should just work. At the very least it should be far, far easier that GAE.<p>(The one thing you&#x27;ll have to watch out for are C-extensions, which, for now, require that you do your deployment from an x86_64 machine.)