I have had some interesting experiences, the most challenging being DMT.<p>It worked in the following way. During our daily lives, all inputs from out senses are filtered. I imagine that the brain filters the &quot;raw steam&quot; because it is way to much data to consistently process effectively. I think this is why you tend to notice things that have been moved in a room, even if you might not immediately know what it was that had moved. I believe that game programmers use these kind of visual screen drawing tricks all the time.<p>DMT gives you the ability to see the world without filters for a short period of time. At some point during that unfiltered view the brain can&#x27;t take it anymore, and it reboots.<p>Both parts of this experience are both fascinating and terrifying. When you reboot, there is no you. No ego. It takes a while for the brain to work out what you are, before who you are, and then finally what the fuck just happened!<p>It&#x27;s nickname is &quot;the businessman&#x27;s trip&quot;. There is no come down.