Peewee [1] is my tool of choice because of its convenience and flexibility combined. I can create pretty complex queries using its Query API, but also execute arbitrary queries when I know I need something a little more nonstandard. Plus the maintainer (Charles Leifer) is an awesome dude who has always been really helpful to his users.<p>[1] Peewee: <a href="https:&#x2F;&#x2F;github.com&#x2F;coleifer&#x2F;peewee" rel="nofollow">https:&#x2F;&#x2F;github.com&#x2F;coleifer&#x2F;peewee</a>