&gt;  I do not think delaying puberty is reversible<p>Then you are wrong. Simple as that. There&#x27;s been plenty of published research investigating these drugs and their effect, both physical and otherwise.<p>&gt; Puberty is an integral part of growing up and maturing into an adult. Delaying it will change the child&#x27;s mental make-up and I do not consider that to be natural or something that should be done with anybody.<p>Going through puberty as the &quot;wrong gender&quot; for someone with gender dysphoria is associated with a long range of substantial mental health issues that <i>also</i> changes a child mental make-up, and in very negative ways.<p>&gt; IMO the safest thing is to let the child attain majority, and then allow them to make whatever choice they want.<p>The research disagrees with you. These drugs are not used for fun. They are used because they have been shown to ameliorate substantial health issues for these patients. Waiting until they attain majority is too late - the damage has already been done.