babel-register is not recommended for production use.<p><a href="https:&#x2F;&#x2F;phabricator.babeljs.io&#x2F;T6940" rel="nofollow">https:&#x2F;&#x2F;phabricator.babeljs.io&#x2F;T6940</a><p>That being said I&#x27;ve used in production for quite a while, but the memory foot print is a lot higher.  I&#x27;d recommend compiling to a separate file for production.<p>I recently put in the pull request to suggest not using register in production just as babel-node is not recommended.