This is a great study, for nutritional science I am very impressed with the methodology.  It&#x27;s very large and very thorough.  It should be heavily noted that the goal of the study is not to create algorithms for healthy people, but for diabetic and pre-diabetic populations.<p>The only well supported long term consequences of post-prandial high glycemic response <i>in otherwise healthy people</i> is an increased psychological urge to eat.  Outside of that, the importance of insulin levels in healthy people is extremely overhyped.  These machine learning algorithms are cool, and may be useful for diabetic people, but for the general population monitoring your insulin levels is a waste of time.