&gt;<i>Why would you claim this? From what I have read 5-Hydroxytryptophan seem like a widely accepted supplement for issues with Serotonin and&#x2F;or depression and mood.</i><p>The problem is lots of the core science behind brain chemistry is sort of bogus, non reproducible stuff. And a lot of it is sponsored by pharma companies who have an extra motivation for getting (and showing) only the &quot;good&quot; results.