I&#x27;m not 100% sure. I think so, possibly in the same way that exposure therapy can be helpful.<p>On rare occasions when I&#x27;ve forgotten to take my propranolol dose, I think I experienced less severe panic reactions to provoking stimuli compared to in the past. This might be due to higher levels of &#x27;exposure&#x27; when taking propranolol without a concurrent onset of panic symptoms, leading to a partial reversal of &#x27;fear conditioning&#x27; (perhaps better characterised as &#x27;re-conditioning&#x27;?)<p>In my case I&#x27;ve found it to be very effective at treating the symptoms of my panic disorder, which are mostly physical&#x2F;autonomic nervous system mediated. I think beta-blockers wouldn&#x27;t be as effective for anxiety disorders where the symptoms are mostly &#x27;mental&#x27; (e.g. catastrophic thinking, irrational anxious beliefs etc.).<p>tl;dr - Propranolol is great for &#x27;physical&#x27; anxiety, possibly not as effective for &#x27;mental&#x27; anxiety