What is the rate of ultrasounds in these countries?  This deformity is very detectable.  I know that the only treatment, if one can call it that, is termination, but this may be important in coming years.<p>In many communities mothers would commonly opt to terminate these pregnancies.  It&#x27;s harsh and vicious, but it does happen.  We need to think about such sociological differences when predicting this disease.  The wave of birth defects hitting Brazil may not be replicated in countries where ultrasounds are standard and attitudes to termination differ.