This question is facetious, almost as facetious as the &quot;10,000 calories of sawdust&quot;. Almost. The human body can only process so much fat at once based on bile production. On top of all that, I would say no, I wouldn&#x27;t gain several pounds of fat after consuming a whole bottle of olive oil because it wouldn&#x27;t be 3500 calories (12floz = 24 tablespoons * 119 calories = 2856 calories), even assuming I don&#x27;t poop most of it out (as can be seen on Youtube videos). That doesn&#x27;t change the fact that a tablespoon of olive oil contains 119 calories and up to a certain volume the human digestive tract will extract energy from it.<p>Second, I don&#x27;t think three random people would gain the equivalent amount of weight; that&#x27;s one of my points I&#x27;ve made elsewhere. TDEE for different people is different, based on height, weight (heavier people have higher TDEEs, which is ironic because it makes it easier for them to lose weight), and activity level. If you&#x27;re talking three people of the same height, weight, strictly controlled activity level <i>and</i> strictly controlled intake, <i>then</i> I would expect their weight gain to be as close to identical as to make no difference. There&#x27;s always some variance (within 200-300 Kcal: <a href="http:&#x2F;&#x2F;examine.com&#x2F;faq&#x2F;does-metabolism-vary-between-two-people&#x2F;" rel="nofollow">http:&#x2F;&#x2F;examine.com&#x2F;faq&#x2F;does-metabolism-vary-between-two-peop...</a>)<p>Since we&#x27;re cherry picking completely unrealistic intakes, I&#x27;ll pose back to you: if three random people consumed 3500 calories worth of refined sugar, and that exceeded their TDEE by 3500 calories, then yes, each and every one of them would gain 1lb of adipose tissue. Seeing that many in the US easily approach an intake of this much refined sugar in the form of soda, the results (of the population, 2&#x2F;3 is overweight, and 1&#x2F;3 is obese) should not be surprising.