I loved this review. This is systems biology at its best: simple hypotheses let us build models that explain&#x2F;predict emergent behaviour.  How cool to explain that a biological oscillator can produce periodically repeating structures during development!<p>And the title is spot on: without getting hung up on the details we can look for structural insights. There&#x27;s no shame in the &quot;pathetic thinking&quot;. Keeping it simple eliminates the perils of overfitting.