In double-blind tests, one deliberately changes only one variable and compares&#x2F;observes two groups where individual do not know whether they take a new drug or a placebo.  If the drug has a positive effect, the double-blind test is an accepted method of proof, but unfortunately this limits our options severely.  If cancer can be cured by changing _two_ variables, we will never find a cure. NEVER! Remember that we already do research for 50+ years and have spent trillions, so I tend to think that Einstein was right: it is insane to repeat the same experiments and to expect a different outcome.<p>Let&#x27;s jump to Alzheimer, a feared disease with also a lot of research and not so good drugs.  Dr Bredesen has made a protocol with 35 variables to cure Alzheimer.  And in his first test, he reversed Alzheimer in 9 out of 10 patients.  The scientific purists say that there is no double-blind study, so no proof.  I am convinced that Dr Bredesen in on the right path, not only because of the results but also because of his reasoning.  The treatment has no drug, but a health optimization in all possible ways.  And then the body heals itself in 4 months.  Please do not comment with &quot;that cannot be true&quot; unless you proof that it cannot be true (I do not belief that you can provide proof).<p>So the state of current research methods is weak.  Medical research only focuses on one variable, one drug, that will cure a disease.  The results of this way of doing medical research are VERY disappointing.  Trillions are spent and no drugs that cure cancer, AIDS or Alzheimer have been found.  Dr Bredesen has chosen a different path and I support him.