It seems this would be under the assumption that the &quot;dark&quot; network is simply disconnected from the &quot;primary&quot; network, if indeed such a thing exists.<p>One would assume, especially with the measurable loss in gray matter, that these networks are being destroyed and thus couldn&#x27;t be reconnected even if stimulated to do so.<p>But perhaps pruning isn&#x27;t such a binary process and it is these damaged -- but not destroyed -- networks which cause such severe dysfunction.<p>I&#x27;m excited and grateful to the brilliant minds which give hope to so many.  A+, would science again.