This is a baseless critique.<p>No one has to address alternative hypotheses that don&#x27;t make any sense.  Are you unaware that Sanger Sequencing exists, and the actual lesions can be read?  Or that heterologous genes are being introduced with CRISPR methods?  Neither of these common results can be explained by the spontaneous insertion of hundreds of nucleotides that happen to precisely match the sequence of the construct being inserted.<p>Again, this is utter nonsense and demonstrates a complete absence of basic understanding in molecular biology.